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Disturbance-induced degradation and failure evolution of cavity-containing sandstone:Rockburst prevention insights 认领 引用
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作者 Guorui Feng Xiaoze Wen +8 位作者 Jun Guo Shaofeng Wang Wenpu Li Jinwen Bai Quan Liu Ruipeng Qian Cheng Song Jiahao Zhang Daniel Dias 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2026年第5期917-940,共24页
Understanding the mechanisms and mitigation strategies for disturbance-induced rockbursts is essential for ensuring safety in deep rock engineering.To evaluate the effectiveness of drilling pressure relief,uniaxial co... Understanding the mechanisms and mitigation strategies for disturbance-induced rockbursts is essential for ensuring safety in deep rock engineering.To evaluate the effectiveness of drilling pressure relief,uniaxial compression tests were conducted on high-stress,cavity-containing sandstone under low-frequency disturbance loading at various amplitudes.Progressive damage was monitored using acoustic emission and digital image correlation.The threshold disturbance amplitude required to trigger dynamic failure was 25%of uniaxial compressive strength,which was significantly higher than that of intact sandstone.During the stable-damage stage,damage accumulated primarily through small-scale tensile fracturing,whereas large-scale shear fractures developed at later stages,initiating and propagating macrocracks that signalled impending structural instability.The energy-storage limit of cavitycontaining sandstone was found to be independent of the loading path.The input energy during disturbance was stored as elastic strain energy and rapidly exceeded its storage limit,thereby driving crack propagation and rockburst failure.An energy pre-release ratio(EPR)was introduced to quantify the premature release of elastic strain energy induced by cavity instability.For all disturbance amplitudes,the EPR exceeded 45%,demonstrating that the cavity effectively mitigates disturbance-induced rockbursts.The results of this study provide a theoretical basis for evaluating the effectiveness of drilling pressure relief in mitigating disturbance-induced rockbursts. 展开更多
关键词 Low-frequency dynamic disturbance Cavity-containing sandstone AE characteristics Evolution of cracks around the cavity Energy pre-release ratio
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Formation Control of Multi-Agent Systems With Position Constraints on a Closed Curve 认领 引用
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作者 Cheng Song Yongqin He +1 位作者 Jianbin Qiu Shengyuan Xu 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2026年第4期1004-1006,共3页
Dear Editor,This letter deals with the formation control problem of a multiagent system that moves along a closed curve and is subject to position constraints.A distributed formation control law is developed under whi... Dear Editor,This letter deals with the formation control problem of a multiagent system that moves along a closed curve and is subject to position constraints.A distributed formation control law is developed under which the position constraint of each agent can always be satisfied.Due to the existence of position constraints,prescribed formations generally cannot be achieved by the agents. 展开更多
关键词 position constraint multi agent systems distributed formation control law closed curve formation control multiagent system
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Optimization and Sensory Evaluation of the Volatile Oil Extracts from Peucedanum praeruptorum Using Response Surface Methodology and HS-SPME-GC/MS Detection 认领 引用
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作者 Yuxian Liu Jinzhuo Yao +1 位作者 Bangxing Han Cheng Song 《Phyton-International Journal of Experimental Botany》 SCIE 2026年第5期195-212,共18页
Essential oil is one of the main active ingredients in the medicinal herb Peucedanum praeruptorum.However,limited studies have been conducted on the quality evaluation of this essential oil.Here,we performed an optimi... Essential oil is one of the main active ingredients in the medicinal herb Peucedanum praeruptorum.However,limited studies have been conducted on the quality evaluation of this essential oil.Here,we performed an optimization and evaluation of P.praeruptorum volatile oil extraction using response surface methodology.Partial least squares discriminant analysis(PLS-DA)was employed to screen relevant biomarkers.A sensory evaluation of the volatile oil components of P.praeruptorum was conducted across different time periods,and aroma differences were examined.The optimal extraction process involved an extraction time of 4 h,a soaking time of 2 h,a liquid-to-solid ratio of 12 mL/g and an extraction temperature of 132◦C.HS-SPME-GC/MS analysis of the volatile oil composition from different origins,periods and plant parts identified various chemical components,including terpenes,aldehydes,hydrocarbons and ketones.The main components identified were composed ofα-pinene,(-)-β-pinene,3-carene,β-myrcene,D-limonene,β-phellandrene,and other terpenes.The principal component analysis(PCA)revealed clear differences from different origins and time periods.The PLS-DA identified 39 key differential components in the aboveground parts and 20 in the underground parts with variable importance in projection(VIP)values>1.The sensory evaluation analysis described the aroma of P.praeruptorum volatile oil as grassy,woody,spicy,earthy and reminiscent of pine resin,with the most prominent note being spicy.This was highly correlated withβ-pinene,which accounted for the highest proportion.The prominent spicy note was found to be derived from three components:(–)-β-pinene,β-phellandrene,and o-cymene.Our study provides a scientific basis for the evaluation,development and application of volatile oil from P.praeruptorum. 展开更多
关键词 Volatile oil terpenes GC-MS response surface method sensory evaluation
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Multi-Omics Approach in the Transcriptional Regulation of Coumarin Biosynthetic Pathway 认领 引用
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作者 Cheng Song 《Phyton-International Journal of Experimental Botany》 SCIE 2026年第3期98-112,共15页
Coumarin,a significant secondary metabolite derived from the phenylpropanoid pathway,exhibits a broad spectrum of biological activities and medicinal properties.Structurally,coumarins are categorized into simple and a... Coumarin,a significant secondary metabolite derived from the phenylpropanoid pathway,exhibits a broad spectrum of biological activities and medicinal properties.Structurally,coumarins are categorized into simple and angular types based on variations in the core structure of the parent skeleton,with further classifications as furanocoumarins and pyranocoumarins depending on their carbon atom count.In nature,coumarins are predominantly found in plants within families such as Apiaceae,Asteraceae,and Thymelaeaceae.The structural diversity observed among coumarins in higher plants is largely driven by coevolutionary interactions between herbivorous insects and their host plants.With recent advancements in multi-omics technologies,research has increasingly focused on unraveling the transcriptional regulation of key genes in the coumarin biosynthetic pathway.This review consolidates recent findings from genomics,transcriptomics,proteomics,and metabolomics studies to identify,characterize,and regulate coumarin-related genes.These insights provide a foundational reference for further research efforts in gene discovery,molecular regulation,and synthetic biology applications in the context of coumarin biosynthesis. 展开更多
关键词 Coumarin biosynthesis phenylpropanoid transcriptional mechanism medicinal plants genomics
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Preoperative butyrylcholinesterase activity and risk of postoperative delirium:A meta-analysis 认领 引用
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作者 Yuan-Li Qiu Cheng Song +1 位作者 Cui-Wan Huang Wei-Gang Shen 《World Journal of Psychiatry》 SCIE 2026年第1期385-399,共15页
BACKGROUND Postoperative delirium(POD)is a common and serious complication in surgical patients,particularly older adults.Alterations in cholinergic function have been implicated in its pathophysiology.AIM To evaluate... BACKGROUND Postoperative delirium(POD)is a common and serious complication in surgical patients,particularly older adults.Alterations in cholinergic function have been implicated in its pathophysiology.AIM To evaluate the association between preoperative serum cholinesterase(ChE)activity—specifically butyrylcholinesterase(BuChE)and acetylcholinesterase(AChE)—and the risk of POD in adult surgical patients in a meta-analysis.METHODS A systematic search was conducted in PubMed,EMBASE,and Web of Science up to March 28,2025 for studies reporting preoperative serum BuChE or AChE activity in relation to subsequent POD incidence.Standardized mean differences(SMDs)and odds ratios(ORs)with 95%confidence intervals(CIs)were pooled using random-effects models.Subgroup and sensitivity analyses were performed based on follow-up duration and analytic models.RESULTS Thirteen studies(n=2730 patients)were included.Patients who developed POD had significantly lower preoperative BuChE activity than those who did not(SMD=-0.28;95%CI:-0.39 to-0.16;I2=18%).Higher BuChE activity was associated with a reduced risk of POD(OR per 100 unit increment=0.97;95%CI:0.95-0.99;I2=0%).In contrast,pooled AChE activity did not differ significantly between POD and non-POD groups(SMD=-0.25;95%CI:-0.53 to 0.03;P=0.08;I2=80%),and the ORs per 1 unit increment in AChE activity were not statistically significant(OR=0.98;95%CI:0.95-1.01).CONCLUSION Lower preoperative serum BuChE activity is associated with an increased risk of POD in adults undergoing surgery.BuChE activity may serve as a potential preoperative biomarker for POD risk stratification. 展开更多
关键词 Acetylcholinesterase Butyrylcholinesterase Activity Postoperative delirium Meta-analysis
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基于频域介电特性的油浸式变压器局部绝缘老化程度评估方法 认领 引用
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作者 张明泽 邵迪 +3 位作者 刘骥 程嵩 刘贺千 池明赫 《高电压技术》 EI CAS CSCD 北大核心 2026年第7期3405-3416,共12页
油纸绝缘作为油浸式变压器的主要绝缘体系,承受了复杂、苛刻的运行工况,长期运行下变压器内部局部绝缘老化程度增加,绝缘性能下降,严重影响变压器的稳定安全运行,因此明确油浸式变压器局部绝缘老化状态的评估方法,对保障电网稳定运行至... 油纸绝缘作为油浸式变压器的主要绝缘体系,承受了复杂、苛刻的运行工况,长期运行下变压器内部局部绝缘老化程度增加,绝缘性能下降,严重影响变压器的稳定安全运行,因此明确油浸式变压器局部绝缘老化状态的评估方法,对保障电网稳定运行至关重要。该文在实验室环境下针对变压器油、油浸纸板开展了不同温度下的频域介电响应测试,揭示了水分含量、绝缘老化程度、测试温度对其交流电导率变化的影响规律;同时,基于变压器高低压绕组主绝缘结构,构建了变压器主绝缘分布等效电导率计算模型,提出了基于介电响应数据自适应扩充的油浸式变压器局部绝缘老化状态评估方法,实现了多参数耦合方程组的求解,并通过不均匀老化缩比模型试验,验证了该方法的有效性。该研究结果可为电力部门运维决策提供一定的理论依据及技术参考。 展开更多
关键词 油纸绝缘 交流电导特性 频域介电响应 优化算法 绝缘状态评估
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平衡结算规则下多环节电力市场出清算法设计 认领 引用
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作者 周鑫 程松 +2 位作者 任景 高敏 李文萱 《自动化仪表》 CAS 2026年第8期111-114,120,共4页
新能源出力不确定性问题制约电力系统的安全、经济运行,增加了市场出清的难度,降低了出清算法的灵活性。为此,设计了平衡结算规则下多环节电力市场出清算法。设计市场运作模式并将该模式纳入平衡结算规则,以应对新能源出力不确定性挑战... 新能源出力不确定性问题制约电力系统的安全、经济运行,增加了市场出清的难度,降低了出清算法的灵活性。为此,设计了平衡结算规则下多环节电力市场出清算法。设计市场运作模式并将该模式纳入平衡结算规则,以应对新能源出力不确定性挑战,实现电力市场稳定运行和供需平衡。在此基础上,考虑输电和配电系统的要求,建立多环节市场出清模型。在求解模型前,对模型中的非线性项和非线性约束作线性化处理,并恢复二阶锥松弛误差,以得到最优的市场出清结果。试验结果表明:所提算法计算效率高、出清效果好。该算法在实际应用中具有较强的灵活性。 展开更多
关键词 新能源 平衡结算规则 出力不确定性 市场运作模式 多环节电力市场 出清算法
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Development of recombinase-aided amplification assays with realtime fluorescence and lateral flow dipstick for the rapid detection of Actinobacillus pleuropneumoniae 认领 引用 被引量：1
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作者 Haoran Kang Deyu Li +6 位作者 Cheng Song Yongning Zhang Lei Zhou Xinna Ge Jun Han Xin Guo Hanchun Yang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2025年第12期4815-4820,共6页
Porcine Contagious Pleuropneumonia(PCP)is a respiratory infectious disease of pigs caused by Actinobacillus pleuropneumoniae.The disease has been prevalent in pig farms since it was first identified in 1957(Pattison e... Porcine Contagious Pleuropneumonia(PCP)is a respiratory infectious disease of pigs caused by Actinobacillus pleuropneumoniae.The disease has been prevalent in pig farms since it was first identified in 1957(Pattison et al.1957). 展开更多
关键词 porcine contagious pleuropneumonia pcp recombinase aided amplification Actinobacillus pleuropneumoniae lateral flow dipstick actinobacillus pleuropneumoniaethe respiratory infectious disease Porcine contagious pleuropneumonia realtime fluorescence
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猫源支气管败血波氏杆菌的分离鉴定及致病性研究 认领 引用 被引量：1
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作者 李皖萧 王佳玲 +9 位作者 胡青海 张子晨 王锦斌 程松 丛雁方 王桂军 李传峰 孟春春 朱杰 刘光清 《中国动物传染病学报》 CAS 北大核心 2026年第1期47-52,共6页
本研究从罹患上呼吸道感染的猫鼻拭子样本中分离到1株疑似菌株,并进行了病原菌的分离培养、革兰氏染色和镜检、麦康凯和鲍-姜氏培养基筛选,对筛选到的病原菌进一步进行生化试验和16S rRNA鉴定,最后对病原菌进行药敏试验和动物回归试验。... 本研究从罹患上呼吸道感染的猫鼻拭子样本中分离到1株疑似菌株,并进行了病原菌的分离培养、革兰氏染色和镜检、麦康凯和鲍-姜氏培养基筛选,对筛选到的病原菌进一步进行生化试验和16S rRNA鉴定,最后对病原菌进行药敏试验和动物回归试验。16S rRNA基因检测与测序结果表明,该菌株属于典型猫支气管败血波氏杆菌,与GenBank上公布的多株参考序列同源性为98.0%~100%,该细菌可以在鲍-姜氏平板上生长,菌落呈现圆形、光滑、边缘整齐。生化反应试验结果显示,该菌株符合波氏菌属细菌典型反应特征;药敏试验结果显示,该菌对氯霉素、新霉素、红霉素等敏感,对氨苄西林、链霉素、利福平、磷霉素和呋喃唑酮耐药。该菌株对小鼠的半数致死量为6.25×108 CFU;对猫的感染试验结果显示,该菌株对猫具有较强的致病性,能引起典型上呼吸道症状。综上所述,我们成功分离到1株对猫具有强致病性的支气管败血波氏杆菌,为宠物支气管败血波氏杆菌的检测和疫苗研发奠定了物质基础。 展开更多
关键词 支气管败血波氏杆菌 分离鉴定 生化试验 耐药性 致病性
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Integrating biochemical pathways,transcriptional regulation,proteomics,and genetic approaches for enhancing salt stress tolerance in crops 认领 引用
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作者 Muhammad Usman Muhammad Azam +4 位作者 Cheng Song Nousheen Yousaf Zishan Ahmad Ghulam Murtaza Muhammad Aamir Manzoor 《Tropical Plants》 CSCD 2025年第1期113-128,共16页
Excessive salt concentrations in plants disrupt vital biochemical and physiological processes,damaging organelles like mitochondria and chloroplasts.To mitigate these effects,plants utilize osmolytes such as glycerol,... Excessive salt concentrations in plants disrupt vital biochemical and physiological processes,damaging organelles like mitochondria and chloroplasts.To mitigate these effects,plants utilize osmolytes such as glycerol,sorbitol,proline(Pro),glycine betaine(GB),and gamma-aminobutyric acid(GABA),which help maintain cellular turgor and water balance under osmotic stress.Antioxidant defense mechanisms,including enzymatic(e.g.,peroxidase,superoxide dismutase,catalase)and non-enzymatic compounds,are essential for salt stress tolerance(SST).These enzymes,upregulated under salt stress,detoxify reactive oxygen species(ROS)and protect cells from oxidative damage.Transcription factors(TFs)such as AP2/EREBP,WRKY,bZIP,GRAS,MYB,GATA,bHLH,and NAC regulate stress-responsive genes and are critical for plant adaptation to abiotic stresses.bZIPs enhance SST in rice,while GATAs are induced by salt stress across various species.NAC TFs interact with hormone signaling pathways like ABA to modulate gene expression in response to oxidative stress and ion imbalance.Additionally,specialized ion transporters(e.g.,Na+/H+antiporters and HKT1)and phytohormones such as ABA play pivotal roles in maintaining ion homeostasis and orchestrating stress responses under salinity.Advancements in metabolomics,proteomics,transcriptomics,and genomics have significantly advanced our understanding of the molecular mechanisms underlying salt stress tolerance.By studying biochemical pathways,protein dynamics,gene expression,and genomic variations,researchers are uncovering critical networks involved in ion homeostasis,ROS detoxification,and osmotic regulation.This review synthesizes current data,demonstrating how multi-omics approaches enhance our knowledge of salt stress adaptation and offering promising avenues for biotechnological interventions aimed at improving crop resilience. 展开更多
关键词 biochemical pathways osmolytes proteomics genetic approaches biochemical physiological processesdamaging transcriptional regulation salt stress tolerance defense mechanismsincluding
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Characterization of pyrolytic properties of pyrite in the terahertz frequency band 认领 引用
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作者 Tong Zhang Cheng Song +4 位作者 Zhi-Yuan Zheng Si-Qi Zhang Hao-Chong Huang Jun-Feng Shen Xiao-Wei Li 《Applied Geophysics》 SCIE CSCD 2025年第4期1351-1358,1500,共8页
A systematic terahertz spectroscopy study of the mineral phase transformation process of natural pyrite samples heated in a nitrogen atmosphere is conducted.In addition,the pyrolysis process of pyrite in the 400℃–80... A systematic terahertz spectroscopy study of the mineral phase transformation process of natural pyrite samples heated in a nitrogen atmosphere is conducted.In addition,the pyrolysis process of pyrite in the 400℃–800℃temperature range is analyzed and discussed.This study is based on X-ray diffraction(XRD)and thermogravimetric–derivative thermogravimetric(TG-DTG)analysis of the corresponding thermal transformation sequences of pyrite,magnetopyrite,and sulfurous pyrite as the desulfurization process proceeds.Terahertz time-domain spectroscopy is employed to characterize the optical properties of the pyrolysis products.The results show that pyrite,magnetopyrite and sulfurous pyrite exhibit different absorption coefficients and refractive indices in the terahertz frequency band.The different optical properties of these products provide useful information for the investigation of the pyrolysis process of pyrite and the magnetic properties of environmental sediments. 展开更多
关键词 Pyrite pyrolysis process terahertz technology absorption coefficient
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Probing the Néel Order in Altermagnetic RuO2 Films via X-Ray Magnetic Linear Dichroism 认领 引用
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作者 Yi-Chi Zhang Hua Bai +8 位作者 Dong-Hui Zhang Chong Chen Lei Han Shi-Xuan Liang Rui-Yue Chu Jian-Kun Dai Maciek Sawicki Feng Pan Cheng Song 《Chinese Physics Letters》 SCIE EI CAS CSCD 2025年第2期78-87,共10页
The emerging altermagnetic RuO2with both compensated magnetic moments and broken time-reversal symmetry possesses nontrivial magneto-electronic responses and nonrelativistic spin currents that are closely related t... The emerging altermagnetic RuO2with both compensated magnetic moments and broken time-reversal symmetry possesses nontrivial magneto-electronic responses and nonrelativistic spin currents that are closely related to the magnetic easy axis.Ru M3-edge X-ray magnetic linear dichroism(XMLD)measurements were performed to probe the Néel order in RuO2.For epitaxial RuO2 films,characteristic XMLD signals were observed for either RuO2(100)or RuO2(110)at normal incidence or RuO2(001)at oblique incidence.The signals disappeared when the test temperature exceeded the Néel temperature.For non-epitaxial RuO2 films,the flat lines in the XMLD patterns of RuO2(100)and RuO2(110)demonstrate that there is no in-plane uniaxial alignment of the Néel order in these samples because of the counterbalanced Néel order of the twin crystals,as evidenced by X-ray diffraction phi-scan measurements.Our experimental results unambiguously demonstrate antiferromagnetism in RuO2 films and reveal the spatial relation of the Néel order parallel to the RuO2[001]crystalline axis.These findings deepen the understanding of RuO2 and other attractive altermagnetic materials used in the field of spintronics. 展开更多
关键词 temperature magnetic nontrivial
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Melatonin Biosynthesis, Growth Regulation, and Adaptability to Environmental Stress in Plants 认领 引用
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作者 Xiaomei He Xiaoting Wan +4 位作者 Muhammad Arif Ziyang Hu Haiyu Wang Muhammad Aamir Manzoor Cheng Song 《Phyton-International Journal of Experimental Botany》 SCIE 2025年第10期2985-3002,共18页
Melatonin is a multifunctional molecule found in all organisms that has been shown to play a crucial role in plant growth, development, and stress response. Plant melatonin is typically synthesized in organelles terme... Melatonin is a multifunctional molecule found in all organisms that has been shown to play a crucial role in plant growth, development, and stress response. Plant melatonin is typically synthesized in organelles termed chloroplasts, and the mechanisms of its synthesis and metabolic pathways have been extensively studied. Melatonin serves a significant regulatory function in plant growth and development, influencing the morphological and physiological characteristics of plants by modulating biological processes. While studies on plant melatonin receptors are in their early stages compared to studies in animal receptors, the binding mechanism with melatonin is now recognized as the key initiating step that triggers a series of downstream protective effects. This suggests that melatonin in plants may exert its effects through two main modes of target binding. The CAND2/PMTR1 protein binds to melatonin with a high degree of affinity. This binding activates downstream heterotrimeric G proteins, which trigger rapid intracellular signaling cascades. These cascades include activating the MAPK pathway and modulating ion channel activity. This action swiftly regulates stomatal closure in response to physiological processes such as drought stress. Additionally, melatonin has been demonstrated to regulate the plant stress response through two main mechanisms. First, it directly inhibits the accumulation of reactive oxygen species. Second, it indirectly influences the stress response pathways. This paper examines plant melatonin from three perspectives: the synthesis pathways of melatonin, its effects on plant growth, and its applications in plants under stress. Finally, the prospects for melatonin study and its applications in plants are discussed. 展开更多
关键词 Melatonin biosynthetic pathway secondary metabolism growth regulation environmental stress
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低密度聚乙烯基碳纳米管的制备及其电磁波吸收性能评价 认领 引用
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作者 陶畅 程松 +8 位作者 邢宝林 孟卫波 毋浩楠 康伟伟 曾会会 屈笑笑 郝睿 张传祥 方纪 《化工进展》 EI CAS CSCD 北大核心 2026年第5期3156-3168,共13页
以低密度聚乙烯(LDPE)为原料,FeCo/MnO为催化剂前体,通过原位热解法制备了碳纳米管(CNTs)基氧化锰复合吸波材料(CNT@MnO),并评价了其电磁波(EMW)吸收性能,提出了具有良好EMW吸收性能的LDPE基碳纳米管制备有效方法。系统地研究了热解温度... 以低密度聚乙烯(LDPE)为原料,FeCo/MnO为催化剂前体,通过原位热解法制备了碳纳米管(CNTs)基氧化锰复合吸波材料(CNT@MnO),并评价了其电磁波(EMW)吸收性能,提出了具有良好EMW吸收性能的LDPE基碳纳米管制备有效方法。系统地研究了热解温度(600~800℃)以及预催化剂中MnO添加量对CNTs@MnO形貌结构的影响机制,优化了CNTs@MnO的制备工艺,建立了不同制备条件与CNTs@MnO微观结构间的内在关系,揭示了CNTs的生长机理,构建了不同形貌结构CNTs@MnO与其EMW吸附性能之间的“构效”关系。研究结果表明,在700℃下能够获得形貌结构较好的CNTs,增加催化剂中MnO的含量会使竹状CNTs含量下降,管状CNTs增加。透射电镜及扫描电镜结果显示,CNTs包含顶端和底端两种生长机制,且温度和催化剂组成会影响竹状CNTs的形成。预催化剂FeCo/MnOx1在700℃制备条件下获得的CNTs@MnO具有最佳的吸波性能,在2.5mm的涂层厚度下能够达到-53.35dB的最大反射损耗,在1.9mm的涂层厚度下有效吸收宽度为4.43GHz(13.24~17.67GHz)。CNTs@MnO的主要电磁损耗机制为传导损耗,MnO的存在使得CNTs的阻抗匹配得到优化,避免了EMW在其表面的反射。 展开更多
关键词 低密度聚乙烯 碳纳米管 催化剂 碳氢化合物 电磁波吸收材料
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1株猫源鹦鹉热衣原体的分离与鉴定 认领 引用
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作者 王诗诗 朱雯琪 +4 位作者 庞帅赛 邓应坤 程松 刘光清 孟春春 《中国兽医学报》 CAS CSCD 北大核心 2026年第5期1047-1052,共6页
为了解猫源鹦鹉热衣原体(Chlamydia felis,C.felis)在宠物猫中的流行情况及潜在的公共卫生风险,本研究对1只疑似患有上呼吸道感染(upper respiratory tract disease,URTD)的病死猫脏器进行相关病原检测。将处理后的样品利用SPF鸡胚进行... 为了解猫源鹦鹉热衣原体(Chlamydia felis,C.felis)在宠物猫中的流行情况及潜在的公共卫生风险,本研究对1只疑似患有上呼吸道感染(upper respiratory tract disease,URTD)的病死猫脏器进行相关病原检测。将处理后的样品利用SPF鸡胚进行分离培养,通过吉姆萨染色、透射电镜观察等方法对分离株进行鉴定。结果表明,病死猫的肺脏检出衣原体特异性核酸。样品研磨液接种SPF鸡胚后,病死鸡胚的胚体出现衣原体样典型病变。使用鹦鹉热衣原体国标ompA鉴定引物可扩增出阳性条带。鸡胚半数致死量(median egg lethal dose,ELD50)试验表明,该分离株第4代的滴度为1.9×105 ELD50/0.1 mL;通过Giemsa染色可在病死鸡胚卵黄囊膜中观察到圆形或椭圆形的包涵体,电镜下可观察到原体(elementary body,EB)和网状体(rticulate body,RB)的典型结构。对该分离株ompA基因的核苷酸序列进行遗传进化树分析,发现与猫衣原体Fe/C-56株在同一分支并且与鹦鹉热衣原体6BC亲缘性最近。综上,研究分离到1株C.felis,并命名为C.felis-SH 23。该研究为后续C.felis的致病力检测和疫苗研发提供了生物材料支持。 展开更多
关键词 猫源鹦鹉热衣原体 分离鉴定 ompA基因
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利奈唑胺联合亚胺培南西司他丁辅助常规抗结核疗法治疗肺结核合并重症肺炎临床研究 认领 引用
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作者 李娅敏 成松 +3 位作者 孙景坤 张礼营 彭乐 袁苗 《中国药业》 CAS 2026年第1期99-103,共5页
目的探讨利奈唑胺联合亚胺培南西司他丁辅助常规抗结核疗法治疗肺结核合并重症肺炎的临床疗效与安全性。方法选取医院结核科与重症监护室2020年1月至2024年3月收治的肺结核合并重症肺炎住院患者312例,按随机数字表法分为对照组和观察组,... 目的探讨利奈唑胺联合亚胺培南西司他丁辅助常规抗结核疗法治疗肺结核合并重症肺炎的临床疗效与安全性。方法选取医院结核科与重症监护室2020年1月至2024年3月收治的肺结核合并重症肺炎住院患者312例,按随机数字表法分为对照组和观察组,各156例。对照组患者采用常规抗结核疗法联合亚胺培南西司他丁治疗,观察组患者在对照组治疗基础上加用利奈唑胺。两组患者均连续治疗2周,随访12个月。结果观察组治疗总有效率为85.90%,细菌清除率为88.46%,1年生存率为92.31%,分别显著高于对照组的77.56%,64.74%,85.26%(P0.05)。观察组与对照组患者不良反应发生率相当(4.49%比3.85%,P>0.05)。结论利奈唑胺联合亚胺培南西司他丁辅助常规抗结核疗法治疗肺结核合并重症肺炎的临床疗效良好,展现了强效协同抑菌的特性,在促进机体免疫功能恢复及减轻炎性损伤方面优势明显,且安全性较好。 展开更多
关键词 利奈唑胺 亚胺培南西司他丁 肺结核 重症肺炎 抗病毒 免疫功能 T淋巴细胞亚群 临床疗效
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Zinc Oxide Nanoparticle Alleviates the Inhibition of Dendrobium huoshanense Photosynthesis by Cadmium through Enhancing Antioxidant Enzyme System 认领 引用
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作者 Cheng Song Iftikhar Hussein Shah +2 位作者 Ghulam Abbas Ashraf Muhammad Arif Muhammad Aamir Manzoor 《Phyton-International Journal of Experimental Botany》 SCIE 2025年第11期3427-3451,共25页
Heavy metal pollution has become a pervasive environmental issue affecting numerous regions worldwide.Recently,there has been significant attention given to the application of nano-enabled technologies with the purpos... Heavy metal pollution has become a pervasive environmental issue affecting numerous regions worldwide.Recently,there has been significant attention given to the application of nano-enabled technologies with the purpose of enhancing plant development and alleviating heavy metal stress.This study aimed to illustrate the potential of zinc oxide nanoparticles(ZnO-NPs)to enhance the morphological traits of D.huoshenense exposed to cadmium(Cd)stress.The chemical structure and elemental composition of the ZnO-NPs were characterised by a series of analytical methods,including X-ray diffraction,UV-Vis spectrometry,XPS,andTEM.Plant samples usedwere collected at 0,5,and 15 days in order to assess physiological and biochemical parameters under different Cd treatments.ZnONPs administered in pot experiments have been shown to enhance plant proliferation through the modulation of Cd enrichment levels.The results revealed that ZnO-NPs enhanced plant growth by increasing soluble sugars and proline levels,enhancing activities of antioxidant enzymes(SOD,POD,CAT,APX)and reducing electrolyte leakage(EL)and malondialdehyde(MDA)content.Furthermore,ZnO-NPs enhanced the net photosynthetic rate,transpiration,stomatal conductance,and chlorophyll content in leaves subjected to Cd stress at the 10-day sampling stage.Exogenous ZnO-NPs significantly elevated the expression of genes associated with flavonoid biosynthesis,potentially facilitating the accumulation of medicinal compounds to mitigate Cd stress.Taken together,these findings provide a novel perspective on the strategies employed by medicinal plants in response to Cd. 展开更多
关键词 Zn oxide nanoparticles cadmium plant physiology photosynthesis antioxidant enzymes Dendrobium huoshenense
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Plant Secondary Metabolism and Functional Biology 认领 引用
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作者 Cheng Song Muhammad Abdullah Muhammad Aamir Manzoor 《Phyton-International Journal of Experimental Botany》 SCIE 2025年第9期2949-2955,共7页
1 Plant SecondaryMetabolism and Functional Biology Progress Plants have long been recognized as biochemical powerhouses,producing a vast array of compounds through their secondary metabolic pathways[1].Although histor... 1 Plant SecondaryMetabolism and Functional Biology Progress Plants have long been recognized as biochemical powerhouses,producing a vast array of compounds through their secondary metabolic pathways[1].Although historically referred to as‘secondary’due to their perceived non-essential role in basic plant survival,it is now understood that these metabolites are integral to plant growth,development and adaptation to environmental challenges.Secondary metabolites,such as alkaloids,terpenoids,phenolics and flavonoids,serve as critical mediators of plant-environment interactions,conferring resistance to biotic and abiotic stressors[2].Beyond their ecological functions,these compounds are invaluable to humans,supporting industries ranging from pharmaceuticals and nutrition to agrochemicals and chemical additives. 展开更多
关键词 alkaloids flavonoids secondary metabolic pathways biochemical powerhouses functional biology terpenoids phenolics plant secondary metabolism
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基于聚类与SDC算法的智能仓储系统分类识别技术研究 认领 引用
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作者 侯晓辉 王金山 +2 位作者 吴艳明 程嵩 齐佳丽 《工业仪表与自动化装置》 2026年第2期84-89,共6页
该文以YOLOv8为基本框架,在主干框架中添加SDC增加图像特性提取能力,并在检测头中添加改进损失函数强化位置识别能力;使用聚类算法和神经网络耦合来输出货物信息。该文提出的改进模型在5种不同类别货物检测中,相比于无锚框算法YOLOv8,P... 该文以YOLOv8为基本框架,在主干框架中添加SDC增加图像特性提取能力,并在检测头中添加改进损失函数强化位置识别能力;使用聚类算法和神经网络耦合来输出货物信息。该文提出的改进模型在5种不同类别货物检测中,相比于无锚框算法YOLOv8,PA值分别提升了8.04%,8.26%,8.18%,7.49%和7.41%,mPA值提升了7.35%。在图像特征采集后,基于概率的聚类分析展现出良好地分类效果,对于货架层、地面层和地面货架混合层的货物进行测试。货架层和地面层的识别准确率分别为97.1%和96.8%。而混合环境下,准确率为94.2%。 展开更多
关键词 智能仓储 聚类分析 SDC 机器视觉 分类识别
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Copper-catalyzed regioselective acyloxy-trifluoromethylation of allenamides with togni'sⅡreagent 认领 引用
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作者 TONG Xiang-yan CHENG Song +4 位作者 ZHAO Qi LUO Cheng-xiang PENG Lin-Jie LI Xiao-xiao ZHAO Zhi-gang 《化学研究与应用》 CAS 北大核心 2025年第3期631-643,共13页
An efficient copper-catalyzed regioselective acyloxy-trifluoromethylation of allenamides using Togni'sⅡreagent as the source of both the trifluoromethyl and acyloxy moieties was developed to create a workable rou... An efficient copper-catalyzed regioselective acyloxy-trifluoromethylation of allenamides using Togni'sⅡreagent as the source of both the trifluoromethyl and acyloxy moieties was developed to create a workable route to CF3-substituted allylic esters.The reaction exhibited good functional group tolerance and high efficiency,affording the products in moderate to good yields.Mechanistic investigations indicated a radical process was likely involved in this transformation. 展开更多
关键词 allenamides Togni's reagent acyloxy-trifluoromethylation copper-catalyzed
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