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Sphenopalatine ganglion stimulation:Clinical applications and innovative development 认领 引用
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作者 Ling-li QIN Yue GAO +5 位作者 Jian-wu SHEN Ran LUO Dian CHEN Wan-ying XIA Jin-sheng YANG Lu ZHANG 《World Journal of Acupuncture-Moxibustion》 CAS CSCD 2026年第1期61-66,共6页
The sphenopalatine ganglion(SPG)is a critical parasympathetic ganglion located beneath the maxillary nerves.Its anatomical structure and function play key roles in the regulation of cerebral blood vessels,the autonomi... The sphenopalatine ganglion(SPG)is a critical parasympathetic ganglion located beneath the maxillary nerves.Its anatomical structure and function play key roles in the regulation of cerebral blood vessels,the autonomic nervous system,and various headache-related disorders.In recent years,SPG stimulation(SPGS)has been widely applied in both invasive and acupuncture-mediated clinical practice.This paper outlines the current clinical applications of SPGS in treating conditions such as headaches,strokes,and rhinitis,and explores how innovative technologies,including ultrasound-guided techniques and singleuse sterile electrode acupuncture needles,may enhance therapeutic efficacy.The potential future development of SPGS in the field of neuromodulation is also discussed. 展开更多
关键词 Sphenopalatine ganglion Sphenopalatine ganglion stimulation technology Neuromodulation Single-use sterile electrode acupuncture needle
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Modeling of bolted beam utilizing modified joint element and identification of contact parameters at the joint 认领 引用
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作者 Xiang Li Zhousuo Zhang +1 位作者 Zhuofan Zhou Dian Chen 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2026年第2期374-382,共9页
Research on the modeling of bolted connection structures primarily centers on the characterization of the connection interface.Accurate equivalent modeling of the connection interface is crucial for the effective mode... Research on the modeling of bolted connection structures primarily centers on the characterization of the connection interface.Accurate equivalent modeling of the connection interface is crucial for the effective modeling of bolted connection structures.This article considers the misalignment between the bolt plane and the beam plane,and establishes a modified joint element representing the bolted connection by using the seriesstiffness method.The contact stiffness in this modified joint element are identified using a genetic algorithm with an “emperor selection” strategy.The bolted connection beam model is achieved by refining the Euler-Bernoulli beam model through the incorporation of a modified joint element.The maximum error between the model calculation results and experimental results for each order of natural frequency is 2.39%.This demonstrates the feasibility of accurately characterizing the bolted connection beam through the utilization of the modified joint element for equivalent modeling.This research proposes a modeling method for bolted connection beams that accounts for the misalignment between the bolt plane and the beam plane,significantly enhancing modeling accuracy. 展开更多
关键词 Bolted joints Modified joint element Genetic algorithm Parameter identification
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NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts 认领 引用 被引量：5
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作者 Ling Ye Feng Lou +11 位作者 Fanyuan Yu Demao Zhang Chenglin Wang Fanzi Wu Xin Li Yilin Ping Xiao Yang Jing Yang Dian Chen Bo Gao Dingming Huang Peng Liu 《Bone Research》 SCIE CAS CSCD 2018年第4期368-382,共15页
The adaptor protein NUMB is involved in asymmetric division and cell fate determination and recognized as an antagonist of Notch.Previous studies have proved that Notch activation in osteoblasts contributes to a high ... The adaptor protein NUMB is involved in asymmetric division and cell fate determination and recognized as an antagonist of Notch.Previous studies have proved that Notch activation in osteoblasts contributes to a high bone mass. In this study, however, an osteopenic phenotype was found in 9-week-old mice using osteoblastic specific Col1a1–2.3-Cre to ablate both Numb and its homologue Numbl. The trabecular bone mass decreased dramatically while the cortical bone mass was unaffected. Here, the Notch signal was not activated,while the tensin homologue deleted on human chromosome 10(PTEN), which dephosphorylates phosphatidylinositide 3-kinases, was elevated, attenuating protein kinase B(Akt). The ubiquitination assay revealed that NUMB may physiologically promote PTEN ubiquitination in the presence of neural precursor cell-expressed developmentally downregulated protein 4–1. In addition, the deficiency of Numb/Numbl also activated the Hedgehog pathway through GLI1. This process was found to improve the ratio of the receptor activator of nuclear factor-k B ligand to osteoprotegerin, which enhanced the differentiation of osteoclasts and bone resorption. In conclusion, this study provides an insight into new functons of NUMB and NUMBL on bone homeostasis. 展开更多
关键词 NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts GLI RANKL
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The impact of the Rural Minimum Living Standard Guarantee(Rural Dibao)Program on child nutrition outcomes 认领 引用 被引量：1
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作者 Dian Chen Xiangming Fang +3 位作者 Yu Chen Xiaodong Zheng Zhuo Chen Rodney B.W.Smith 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第2期444-456,共13页
The Rural Minimum Living Standard Guarantee(Rural Dibao)is an important unconditional cash transfer program to alleviate poverty in rural China.Despite the importance of children’s nutrition in breaking poverty cycle... The Rural Minimum Living Standard Guarantee(Rural Dibao)is an important unconditional cash transfer program to alleviate poverty in rural China.Despite the importance of children’s nutrition in breaking poverty cycles,little is known about the impact of Rural Dibao on child nutrition outcomes.Using China Family Panel Studies(CFPS),this paper examines the effects of Rural Dibao on child nutrition outcomes and investigates potential pathways and heterogeneous effects.We exploit propensity score matching and difference-in-differences techniques to evaluate the effects of the Rural Dibao program on child nutrition outcomes.Our results suggest that Rural Dibao significantly impacts the nutrition outcomes of children up to 15 years of age.Specifically,our results suggest that Rural Dibao improves child height-to-age z-scores by 1.05 standard deviations and lowers the probability of stunting by 11.9 percentage points.Additional analyses suggest that increased protein intake is the main pathway through which Rural Dibao participation contributes to better nutrition outcomes.We also find that the effect of the program is more pronounced among girls,children who are non-left-behind or live with highly educated mothers,and those from low-income families and poor areas.Our findings suggest that Rural Dibao participation helps improve child nutrition outcomes through improving diet quality. 展开更多
关键词 Rural Minimum Living Standard Guarantee nutrition height-to-age z-scores stunting rural China
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Staphylococcus aureus bacteremia and infective endocarditis in a patient with epidermolytic hyperkeratosis:A case report 认领 引用
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作者 Yu Chen Dian Chen +2 位作者 Hao Liu Chen-Guang Zhang Lin-Lin Song 《World Journal of Clinical Cases》 SCIE 2022年第36期13418-13425,共8页
BACKGROUND Staphylococcus aureus bacteraemia(SAB)is among the leading causes of bacteraemia and infectious endocarditis.The frequency of infectious endocarditis(IE)among SAB patients ranges from 5%to 10%-12%.In adults... BACKGROUND Staphylococcus aureus bacteraemia(SAB)is among the leading causes of bacteraemia and infectious endocarditis.The frequency of infectious endocarditis(IE)among SAB patients ranges from 5%to 10%-12%.In adults,the characteristics of epidermolytic hyperkeratosis(EHK)include hyperkeratosis,erosions,and blisters.Patients with inflammatory skin diseases and some diseases involving the epidermis tend to exhibit a disturbed skin barrier and tend to have poor cellmediated immunity.CASE SUMMARY We describe a case of SAB and infective endocarditis in a 43-year-old male who presented with fever of unknown origin and skin diseases.After genetic tests,the skin disease was diagnosed as EHK.CONCLUSION A breached skin barrier secondary to EHK,coupled with inadequate sanitation,likely provided the opportunity for bacterial seeding,leading to IE and deepseated abscess or organ abscess.EHK may be associated with skin infection and multiple risk factors for extracutaneous infections.Patients with EHK should be treated early to minimize their consequences.If patients with EHK present with prolonged fever of unknown origin,IE and organ abscesses should be ruled out,including metastatic spreads. 展开更多
关键词 Staphylococcus aureus bacteremia Infective endocarditis Epidermolytic hyperkeratosis Case report
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云南纳板河热带季节雨林20 ha动态监测样地的树种组成与群落分类 认领 引用 被引量：20
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作者 施国杉 刘峰 +2 位作者 陈典 邓云 林露湘 《生物多样性》 CAS CSCD 北大核心 2021年第1期10-20,共11页
大型森林动态监测样地是研究物种共存、群落演替等生态学核心问题的重要平台。纳板河流域国家级自然保护区管理局与中国科学院西双版纳热带植物园合作, 于2016–2017年参照美国史密森热带森林科学中心的技术标准, 在纳板河流域国家级自... 大型森林动态监测样地是研究物种共存、群落演替等生态学核心问题的重要平台。纳板河流域国家级自然保护区管理局与中国科学院西双版纳热带植物园合作, 于2016–2017年参照美国史密森热带森林科学中心的技术标准, 在纳板河流域国家级自然保护区内建立了一块热带季节雨林20 ha动态监测样地。本研究分析了该样地的树种组成特征, 并进行了群落数量分类。结果表明: 该样地中DBH ≥ 1 cm的木本植物个体共有59,498株, 分属63科197属296种;个体数超过1,000株的常见物种有15个, 个体数小于20株的稀有物种有126个。科的区系分布型以热带成分为主, 占总科数的65.08%, 温带成分占17.46%。属的区系分布型以热带成分为主, 占总属数的88.32%, 温带成分占10.66%。该样地群落类型的形成主要受海拔和凹凸度这两个地形因子的影响, 500个20m×20m的样方可以分为4个群丛, 分别为: (1)灰毛浆果楝+粗糠柴-假山萝+番龙眼群丛(Cipadessa baccifera+Mallotus philippensis-Harpullia cupanioides+Pometia pinnata Association);(2)长梗三宝木+腋球苎麻–顶果木+番龙眼群丛(Trigonostemon thyrsoideus+Boehmeria glomerulifera-Acrocarpus fraxinifolius+Pometia pinnata Association);(3)云南银柴+大果山香圆-湄公锥+普文楠群丛(Aporusa yunnanensis+Turpinia pomifera-Castanopsis mekongensis+Phoebe puwenensis Association);(4)歪叶榕+密花火筒树-毒药树+番龙眼群丛(Ficus cyrtophylla+Leea compactiflora-Sladenia celastrifolia+Pometia pinnata Association)。 展开更多
关键词 大型森林动态监测样地 植物区系特征 多元回归树 群丛
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西双版纳热带季节雨林木本植物的beta多样性:空间、环境与林分结构的作用 认领 引用 被引量：2
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作者 施国杉 刘峰 +6 位作者 曹光宏 陈典 夏尚文 邓云 王彬 杨效东 林露湘 《生物多样性》 CAS CSCD 北大核心 2024年第12期56-68,共13页
Beta多样性能够度量物种组成的时空变化格局,其驱动因子(例如空间与环境)一直是生态学研究的热点之一。然而,林分结构作为森林群落重要的特征参数,其对木本植物beta多样性的驱动作用还知之甚少。本研究以云南纳板河热带季节雨林20ha动... Beta多样性能够度量物种组成的时空变化格局,其驱动因子(例如空间与环境)一直是生态学研究的热点之一。然而,林分结构作为森林群落重要的特征参数,其对木本植物beta多样性的驱动作用还知之甚少。本研究以云南纳板河热带季节雨林20ha动态样地的木本植物为研究对象,在不同取样尺度将beta多样性分解为物种周转组分和物种丰富度差异组分,通过基于距离矩阵的多元回归分析和方差分解,解析空间、环境和林分结构在beta多样性及其两个组分格局形成中的相对作用。结果表明:(1)Beta多样性、物种周转组分和物种丰富度差异组分随取样尺度的增大而减小,物种周转组分始终在beta多样性构成中占主导部分。(2)环境距离对beta多样性和物种周转组分具有相对较高的解释率,随着取样尺度增大,单纯的环境距离对beta多样性的解释率从8.8%增长到23.9%,对物种周转组分的解释率从5.1%增长到26.5%;而环境距离对物种丰富度差异组分几乎没有作用。(3)不同取样尺度林分结构距离对beta多样性均具有相对较高的解释率(11.3%-25.1%),并且对物种周转组分和物种丰富度差异组分始终保持一定的解释率。同时,无论是否包含林分结构距离作为解释变量,单纯的空间距离对beta多样性及其两个组分的解释率都很低。本研究支持环境过滤对beta多样性和物种周转组分的相对重要性随着取样尺度的增大而增大的观点,同时发现扩散限制在局域尺度beta多样性格局形成中的作用却十分有限。本研究进一步揭示了能够指示光的可利用性和异质性的林分结构,与地形、土壤等其他环境因子一样,也是beta多样性格局形成的重要驱动力,建议未来深入研究林分结构在木本植物多样性格局形成中的作用机制。 展开更多
关键词 物种周转组分 物种丰富度差异组分 环境过滤 扩散限制 方差分解 取样尺度
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Hydrogen sulfide attenuates oxidative stress-induced cellular senescence via the Sirt3/SOD2 signaling pathway in chronic obstructive pulmonary disease 认领 引用
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作者 Sha Liao Dian Chen +7 位作者 Huanyu Long Simin Jiang Jing Fan Shurun Li Yongfen Qi Lixiang Xue Yanling Ding Yahong Chen 《Chinese Medical Journal》 SCIE CAS CSCD 2026年第6期866-879,共14页
Background:Senescence significantly participates in shaping the pathobiological process underlying chronic obstructive pulmonary disease(COPD).Currently,the mechanisms underlying the anti-aging effects of hydrogen sul... Background:Senescence significantly participates in shaping the pathobiological process underlying chronic obstructive pulmonary disease(COPD).Currently,the mechanisms underlying the anti-aging effects of hydrogen sulfide(H2S)in COPD are not fully illustrated.Methods:Immunohistochemistry(IHC)staining was performed on human lung tissue to detect the expression levels of sirtuin 3(Sirt3),cyclin-dependent kinase 4 inhibitor(P16),and cystathionin gamma lyase(CTH).An animal COPD model including wild-type(WT)and Sirt3 knockout(KO)mice was established by exposing them to cigarette smoking(CS)for 24 weeks,with or without intraperitoneal injection of sodium hydrosulfide(NaHS,50μmol∙L−1∙kg−1)30 min prior to CS exposure.Lung function was assessed.The expression levels of P16,cyclin-dependent kinase inhibitor 1A(P21),Sirt3,manganese superoxide dismutase(SOD2),manganese acetylated superoxide dismutase(ac-SOD2),interleukin-6(IL-6),IL-8,malondialdehyde(MDA),and glutathione(GSH),as well as the activity of SOD2 and Sirt3,were evaluated.Human bronchial epithelial BEAS-2B cells were subjected to diverse cigarette smoking extract(CSE)concentrations for 48 h with or without sodium hydrosulfide(NaHS).Subsequently,the levels of total intracellular reactive oxygen species(T-ROS),mitochondrial reactive oxygen species(mitoROS),mitochondrial membrane potential(MMP),senescence-associated β-galactosidase(SA-β-gal)staining positive cells,and related marker proteins and cytokines were assessed.Furthermore,the Sirt3-specific inhibitor 3-TYP and small interfering RNAs(siRNAs)of Sirt3 were used to examine the mechanisms whereby H2S inhibits oxidative stress and senescence in COPD.Results:IHC showed a significant reduction of CTH and Sirt3 protein levels in the lung tissue of COPD with smoking patients and smokers without COPD compared to non-smokers.Furthermore,the expression of the aging marker protein P16 was notably elevated in the COPD with smoking group compared to the smokers without COPD and non-smoker groups.Furthermore,our results demonstrated that exposure to CS resulted in imbalanced oxidative and cellular senescence,including elevated mitoROS,T-ROS,MDA,and ac-SOD2,along with increased proportions of SA-β-gal staining positive cells and the increased expression levels of IL-6,IL-8,P21,and P16,as well as decreased GSH levels,SOD2 and Sirt3 activities,and Sirt3 expression,which ultimately contribute to emphysema development and impaired lung function.However,pretreatment with NaHS effectively reversed these detrimental effects.Nevertheless,the protective effect of NaHS was alleviated in Sirt3 KO mice and in cellular models treated with Sirt3 siRNA and 3-TYP.Conclusion:Our study indicates that H2S inhibits oxidative stress and cellular senescence by modulating the Sirt3/SOD2 signaling pathway,therefore attenuating the emphysema and impaired lung function induced by CS. 展开更多
关键词 Hydrogen sulfide Cigarette smoking Cellular senescence Chronic obstructive pulmonary disease Oxidative stress Sirtuin 3
Cluster analysis of comorbidity profiles reveals heterogeneity in hospitalized patients with chronic obstructive pulmonary disease 认领 引用 被引量：2
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作者 Haijie Chen Dian Chen +1 位作者 Jing Zhang Yahong Chen 《Chinese Medical Journal》 SCIE CAS CSCD 2025年第4期475-477,共3页
To the Editor:Chronic obstructive pulmonary disease(COPD)is a global health challenge because of its high prevalence and associated mortality.[1]Multimorbidity is a distinguishing feature of COPD in addition to airflo... To the Editor:Chronic obstructive pulmonary disease(COPD)is a global health challenge because of its high prevalence and associated mortality.[1]Multimorbidity is a distinguishing feature of COPD in addition to airflow obstruction.Evaluation from a comorbidity perspective forms part of the comprehensive assessment of COPD.The aim of this study was to analyze the distribution of comorbidities and their impact on the prognosis of patients who are hospitalized with COPD. 展开更多
关键词 hospitalization obstructive pulmonary disease copd comorbidity perspective heterogeneity analyze distribution comorbidities comorbidity chronic obstructive pulmonary disease prognosis
Nested relation extraction with iterative neural network 认领 引用 被引量：6
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作者 Yixuan CAO Dian CHEN +2 位作者 Zhengqi XU Hongwei LI Ping LUO 《Frontiers of Computer Science》 SCIE EI CSCD 2021年第3期109-122,共14页
Most existing researches on relation extraction focus on binary flat relations like Bomln relation between a Person and a Location.But a large portion of objective facts de-scribed in natural language are complex,espe... Most existing researches on relation extraction focus on binary flat relations like Bomln relation between a Person and a Location.But a large portion of objective facts de-scribed in natural language are complex,especially in professional documents in fields such as finance and biomedicine that require precise expressions.For example,“the GDP of the United States in 2018 grew 2.9%compared with 2017”describes a growth rate relation between two other relations about the economic index,which is beyond the expressive power of binary flat relations.Thus,we propose the nested relation extraction problem and formulate it as a directed acyclic graph(DAG)structure extraction problem.Then,we propose a solution using the Iterative Neural Network which extracts relations layer by layer.The proposed solution achieves 78.98 and 97.89 FI scores on two nested relation extraction tasks,namely semantic cause-and-efFect relation extraction and formula extraction.Furthermore,we observe that nested relations are usually expressed in long sentences where entities are mentioned repetitively,which makes the annotation difficult and error-prone.Hence,we extend our model to incorporate a mention-insensitive mode that only requires annotations of relations on entity concepts(instead of exact mentions)while preserving most of its performance.Our mention-insensitive model performs better than the mention sensitive model when the random level in mention selection is higher than 0.3. 展开更多
关键词 nested relation extraction mention insensitive relation iterative neural network
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Twenty years of changes in the definition of early chronic obstructive pulmonary disease 认领 引用 被引量：9
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作者 Dian Chen Jeffrey L.Curtis Yahong Chen 《Chinese Medical Journal Pulmonary and Critical Care Medicine》 2023年第2期84-93,共10页
Chronic obstructive pulmonary disease(COPD)is a chronic inflammatory airway disease that affects the quality of life of nearly one-tenth of the global population.Due to irreversible airflow obstruction and progressive... Chronic obstructive pulmonary disease(COPD)is a chronic inflammatory airway disease that affects the quality of life of nearly one-tenth of the global population.Due to irreversible airflow obstruction and progressive lung function decline,COPD is characterized by high mortality and disability rates,which imposes a huge economic burden on society.In recent years,the importance of intervention in the early stage of COPD has been recognized and the concept of early COPD has been proposed.Identifying and intervening in individuals with early COPD,some of whom have few or no symptoms,might halt or reverse the progressive decline in lung function,improve the quality of life,and better their prognosis.However,understanding of early COPD is not yet well established,and there are no unified and feasible diagnostic criteria,which complicates clinical research.In this article,we review evolution of the definition of early COPD over the past 20 years,describe the changes in awareness of this concept,and propose future research directions. 展开更多
关键词 Chronic obstructive pulmonary disease(COPD) Early COPD Global initiative for chronic obstructive lung disease(GOLD)0 Diagnosis
Common susceptibility loci in both systemic sclerosis and localized scleroderma identified using genetic analysis 认领 引用
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作者 Yun Li Wen-Jun Wang +17 位作者 Wei-Wei Chen Xue Fan Lu Cao Ze-Yu Xing Qi Zhen Qiong-Qiong Xu Chen-Yu Zhu Hui-Yao Ge Dian Chen Rui-Xue Zhang Chang Shu Wei Du Shi-Rui Chen Xie Yuan Hui Zhang Xia Hu Xu-Ming Mao Qiu-Ning Sun 《Chinese Medical Journal》 SCIE CAS CSCD 2020年第19期2370-2372,共3页
Scleroderma is an autoimmune fibrosing disorder that can be further subclassified as localized scleroderma(LSc)and systemic sclerosis(SSc).LSc is characterized by sclerotic and pigmented skin lesions,while SSc is a mo... Scleroderma is an autoimmune fibrosing disorder that can be further subclassified as localized scleroderma(LSc)and systemic sclerosis(SSc).LSc is characterized by sclerotic and pigmented skin lesions,while SSc is a more generalized disorder of the connective tissue involving a number of organs.SSc is characterized by the thickening of dermal collagen bundles,fibrosis,and vascular abnormalities in the visceral organs.[1]Despite the differences in their morphologic features and clinical presentation,these two diseases do share some characteristics including endothelial cell dysfunction,T helper 2(Th2)cell dominance during immune activation and excess fibrosis of the skin with similar pathologic findings,leading to the hypothesis that SSc and LSc share an underlying mechanism of pathogensis.Currently,multiple lines of evidence suggest that genetic factors may contribute to SSc susceptibility. 展开更多
关键词 organs susceptibility spite
Identifying the potential transcriptional regulatory network in Hirschsprung disease by integrated analysis of microarray datasets 认领 引用
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作者 Wenyao Xu Hui Yu +9 位作者 Dian Chen Weikang Pan Weili Yang Jing Miao Wanying Jia Baijun Zheng Yong Liu Xinlin Chen Ya Gao Donghao Tian 《World Journal of Pediatric Surgery》 CSCD 2023年第2期103-114,共12页
Objective Hirschsprung disease(HSCR)is one of the common neurocristopathies in children,which is associated with at least 20 genes and involves a complex regulatory mechanism.Transcriptional regulatory network(TRN)has... Objective Hirschsprung disease(HSCR)is one of the common neurocristopathies in children,which is associated with at least 20 genes and involves a complex regulatory mechanism.Transcriptional regulatory network(TRN)has been commonly reported in regulating gene expression and enteric nervous system development but remains to be investigated in HSCR.This study aimed to identify the potential TRN implicated in the pathogenesis and diagnosis of HSCR.Methods Based on three microarray datasets from the Gene Expression Omnibus database,the multiMiR package was used to investigate the microRNA(miRNA)-target interactions,followed by Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses.Then,we collected transcription factors(TFs)from the TransmiR database to construct the TF-miRNA-mRNA regulatory network and used cytoHubba to identify the key modules.Finally,the receiver operating characteristic(ROC)curve was determined and the integrated diagnostic models were established based on machine learning by the support vector machine method.Results We identified 58 hub differentially expressed microRNAs(DEMis)and 16 differentially expressed mRNAs(DEMs).The robust target genes of DEMis and DEMs mainly enriched in several GO/KEGG terms,including neurogenesis,cell-substrate adhesion,PI3K-Akt,Ras/mitogen-activated protein kinase and Rho/ROCK signaling.Moreover,2 TFs(TP53and TWIST1),4 miRNAs(has-miR-107,has-miR-10b-5p,has-miR-659-3p,and has-miR-371a-5p),and 4 mRNAs(PIM3,CHUK,F2RL1,and CA1)were identified to construct the TF-miRNA-mRNA regulatory network.ROC analysis revealed a strong diagnostic value of the key TRN regulons(all area under the curve values were more than 0.8).Conclusion This study suggests a potential role of the TF-miRNA-mRNA network that can help enrich the connotation of HSCR pathogenesis and diagnosis and provide new horizons for treatment. 展开更多
关键词 diagnosis microarray network
黑潮延伸体综合观测浮标的研制与应用 认领 引用 被引量：3
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作者 陈店 任国庆 +3 位作者 魏兆强 江帆 马昕 陈朝晖 《科学通报》 EI CAS CSCD 北大核心 2023年第17期2250-2257,共8页
浮标是获取水文、气象等环境参数的重要观测技术手段,是现代海洋环境立体监测系统的重要组成部分.西太平洋黑潮延伸体海域是全球海洋动力过程最为复杂、海洋-大气相互作用最为关键的区域之一,也是全球系统性海洋观测相对缺乏的海区之一... 浮标是获取水文、气象等环境参数的重要观测技术手段,是现代海洋环境立体监测系统的重要组成部分.西太平洋黑潮延伸体海域是全球海洋动力过程最为复杂、海洋-大气相互作用最为关键的区域之一,也是全球系统性海洋观测相对缺乏的海区之一,传统的大型海气浮标很难在该海区长期存活.基于此,中国海洋大学研发了一种适用于中纬度海区高海况条件下的大型海气综合观测浮标系统(China Kuroshio Extension Observatory,CKEO).该系统面向深远海大浪、强流、狂风等复杂的工作环境,对高海况下的浮标系统、深水锚系系统、观测系统等做了针对性设计,增强了浮标在高海况下的稳定性和可靠性.截至2022年底,该系列浮标已连续在位工作3年,支撑了对黑潮延伸体海域海-气物质能量交换等科学问题的研究,为“透明海洋”立体观测网络提供了重要的深远海长期观测节点. 展开更多
关键词 浮标 黑潮延伸体 深海综合观测 锚系系统
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