Understanding the creep deformation behavior and the evolution of pore-fracture structures(FPSs)in coal under cyclic loading-unloading is crucial for safe extraction and efficient methane utilization.Coal samples were...Understanding the creep deformation behavior and the evolution of pore-fracture structures(FPSs)in coal under cyclic loading-unloading is crucial for safe extraction and efficient methane utilization.Coal samples were subjected to cyclic loading-unloading creep experiments using online Nuclear Magnetic Resonance(NMR)and Nuclear Magnetic Resonance Imaging(NMRI)techniques.The results revealed the significance of instantaneous plastic and viscoplastic strains during creep,with creep failure modes analyzed using NMRI data and macroscopic fracture distribution.Viscoplastic strain was identified as a key indicator of accelerated failure,and NMRI revealed a transition from splitting-shear to V-shaped shear failure under increasing confining pressure.From a microscopic perspective,real-time T2 spectra monitoring tracked the evolution of FPS at different loading levels,and the geometric mean of the pore structure(T2g)quantitatively described the co-evolution of various pore types.A generalized model was developed to describe coal creep under cyclic loading-unloading,integrating microscopic and macroscopic deformation features and refined using fractal theory.These findings provide theoretical insights and practical guidance for coal extraction and methane management under cyclic loading-unloading creep.展开更多
In high-speed multiuser Time Reversal(TR)downlink systems,the transmission rate is degraded due to the presence of severe inter-user and inter-symbol interference.Moreover,maximizing the weighted sum rate in such syst...In high-speed multiuser Time Reversal(TR)downlink systems,the transmission rate is degraded due to the presence of severe inter-user and inter-symbol interference.Moreover,maximizing the weighted sum rate in such systems is a critical objective,since the weighting factors represent the priority of different users in different applications.However,it faces significant challenges as it is an NP-hard and non-convex problem.In order to suppress these interferences and maximize the weighted sum rate,in this paper we present a novel approach for the joint design of the pre-filters.The proposed method applies successive convex approximation to transform the original problem into a Second-Order Cone Programming(SOCP)problem.Then,a low-complexity iterative algorithm is provided to effectively solve the resulting SOCP problem.According to the simulation results,the proposed method reaches a local optimum within a few iterations and demonstrates superior performance in terms of weighted sum rate compared to the current algorithm.展开更多
Chlorophyll(Chl),a natural pigment with broad applications in food systems,faces challenges due to its instability under light exposure.This study explores the relationship between solvent polarity,charge transfer(CT)...Chlorophyll(Chl),a natural pigment with broad applications in food systems,faces challenges due to its instability under light exposure.This study explores the relationship between solvent polarity,charge transfer(CT)in Chl self-aggregation,and photostability enhancement.By adjusting ethanol/water ratios(10-100%ethanol),environmental polarity was modulated to investigate its impact on CT dynamics using fluorescence spectroscopy,conductivity analysis,and quantum chemistry calculations.Results demonstrated that higher solvent polarity significantly strengthened CT interactions between Chl molecules,primarily mediated by porphyrin rings,while the hydrophobic phytyl tail influenced aggregate configurations and indirectly modulated CT pathways.Light stability tests revealed that Chl retention in high-polarity solvents(10%-40%ethanol)surpassed low-polarity groups(60%-90%ethanol)by 213.04%and 302.61%on days 4 and 8,respectively,highlighting the critical role of CT-driven aggregation in mitigating photodegradation.Quantum calculations further elucidated that phytyl tail removal altered CT efficiency depending on porphyrin spacing:in'sandwich'dimers,phytyl absence enhanced CT,whereas in'face-to-face'configurations,partial removal optimized electron redistribution.These findings underscore solvent polarity as a key regulator of CT-mediated aggregation,offering a mechanism to stabilize Chl through non-covalent interactions.The study advances the understanding of Chl aggregation mechanisms and proposes physical strategies,such as electric-field-induced CT modulation,to enhance the stability of photosensitive natural pigments in food processing and storage.展开更多
Chlorophyll(Chl),the most widely distributed natural pigment in nature,is limited in use due to its poor stability.This study refers to the aggregation structure of Chl and carotene(Car)in natural photosynthetic syste...Chlorophyll(Chl),the most widely distributed natural pigment in nature,is limited in use due to its poor stability.This study refers to the aggregation structure of Chl and carotene(Car)in natural photosynthetic systems,hoping to improve the photostability of Chl by constructing Chl/Car aggregates.The stability protection effect of Car on Chl was explored by designing different ratios of Chl and Car aggregation systems.The configuration of Chl/Car aggregates was optimized through ab initio molecular dynamics,and the aggregation mechanism of the aggregates and the photoprotection mechanism of Chl by Car were elucidated through quantum chemical calculations and wave function analysis.Chl/Car had a 27.22% higher Chl retention rate than free Chl after 7 d of illumination,with a Chl to Car ratio of 1.66:1.A configuration of the Chl/Car aggregates which Car's conjugated olefin chain interacts extensively with the porphyrin ring and bent phytyl chain of Chl made them more stable.The photoprotective mechanism of Car on Chl in the Chl/Car aggregates is elucidated.Car's conjugated polyene chain provides HOMO orbitals to the Chl/Car aggregates.It demonstrated that Car supplies electrons in the low-lying excited states S2 and S4,indicating it is more susceptible to damage,protecting Chl.This research will promote the development of natural color formulas and ensure the health of consumers.展开更多
The security incidents ion networks are sudden and uncertain,it is very hard to precisely predict the network security situation by traditional methods.In order to improve the prediction accuracy of the network securi...The security incidents ion networks are sudden and uncertain,it is very hard to precisely predict the network security situation by traditional methods.In order to improve the prediction accuracy of the network security situation,we build a network security situation prediction model based on Wavelet Neural Network(WNN)with optimized parameters by the Improved Niche Genetic Algorithm(INGA).The proposed model adopts WNN which has strong nonlinear ability and fault-tolerance performance.Also,the parameters for WNN are optimized through the adaptive genetic algorithm(GA)so that WNN searches more effectively.Considering the problem that the adaptive GA converges slowly and easily turns to the premature problem,we introduce a novel niche technology with a dynamic fuzzy clustering and elimination mechanism to solve the premature convergence of the GA.Our final simulation results show that the proposed INGA-WNN prediction model is more reliable and effective,and it achieves faster convergence-speed and higher prediction accuracy than the Genetic Algorithm-Wavelet Neural Network(GA-WNN).Genetic Algorithm-Back Propagation Neural Network(GA-BPNN)and WNN.展开更多
Guizhou Province is an important distribution area of wild onion resources,and a large area of wild( Chinese) chives are distributed in Hezhang County. In order to understand and study the distribution of wild chives,...Guizhou Province is an important distribution area of wild onion resources,and a large area of wild( Chinese) chives are distributed in Hezhang County. In order to understand and study the distribution of wild chives,the geographical distribution,habitats and climate of wild chives in Hezhang County were investigated,and the main nutrition components of wild chives were analyzed. The results indicated that there were mainly three kinds of wild chives distributed in Hezhang County, including Allium wallichii Kunth., Allium ovalifolium Hand.-Mazz.( tentatively named),and Allium hookeri Thwaites( tentatively named). Among the 17 kinds of amino acids,except for proline,the content of other amino acids in wild chives was higher than that of the cultivated chives( Allaum tuberosum Rottler ex Spreng.). The sugar content of wild chives was significantly lower than the cultivated chives. Among nine trace elements,the manganese,zinc and iron content of A. ovalifolium Hand.-Mazz. were significantly higher than that of the cultivated chives and other wild chives. Among the four kinds of heavy metals,cadmium content in the three kinds of wild chives exceeded the limitation of the national standard,and cadmium content in A. ovalifolium Hand.-Mazz. was significantly higher than that of the others. Arsenic,mercury and lead content in A. ovalifolium Hand.-Mazz. also exceeded the limitation of the national standard. Vitamin C content in leaves and stalk of A. wallichii Kunth. in the original habits was higher than that of the cultivated chives. The biological characteristics and nutrition components of the wild chives from Hezhang County were significantly different from that of the cultivated chives. The collection and preservation of these resources are of great significance to the enriching of diversity of Chinese chive resources and has great development and utilization value to the improvement of nutritional quality of Chinese chives.展开更多
N6-methyladenosine (m6A) methylation is the most prevalent and abundant internal post-transcriptional RNA modification in eukaryotic cells, playing an important regulatory role in various biological processes. The bio...N6-methyladenosine (m6A) methylation is the most prevalent and abundant internal post-transcriptional RNA modification in eukaryotic cells, playing an important regulatory role in various biological processes. The biological functions of m6A modification are dynamically and reversibly mediated by methyltransferases (writers), demethylases (erasers), and m6A binding proteins (readers). Acute lung injury (ALI) is a common critical condition characterized by diffuse edema within the pulmonary interstitium and alveoli, and is associated with high morbidity and mortality. Recent studies have identified that aberrant expression of m6A regulators is closely associated with ALI development. This review highlights the progress in research on m6A writers, erasers, and readers in ALI, focusing on their molecular regulatory mechanisms. Elucidating the molecular mechanisms of m6A and its associated proteins in ALI may reveal new therapeutic strategies and targets.展开更多
基金supported by Deep Earth Probe and Mineral Resources Exploration-National Science and Technology Major Project(No.2024ZD1003902)S&T Innovation and Development Project of Information Institution of Ministry of Emergency Management(No.2025506)+2 种基金Special Project for Intergovernmental Cooperation in Scientific and Technological Innovation of National Key Research and Development Program(No.2025YFE0109800)National Natural Science Foundation of China(Nos.52121003 and 51827901)European Commission Horizon Europe Marie Skłodowska-Curie Actions Staff Exchanges Project-LOC3G(No.101129729)。
摘要Understanding the creep deformation behavior and the evolution of pore-fracture structures(FPSs)in coal under cyclic loading-unloading is crucial for safe extraction and efficient methane utilization.Coal samples were subjected to cyclic loading-unloading creep experiments using online Nuclear Magnetic Resonance(NMR)and Nuclear Magnetic Resonance Imaging(NMRI)techniques.The results revealed the significance of instantaneous plastic and viscoplastic strains during creep,with creep failure modes analyzed using NMRI data and macroscopic fracture distribution.Viscoplastic strain was identified as a key indicator of accelerated failure,and NMRI revealed a transition from splitting-shear to V-shaped shear failure under increasing confining pressure.From a microscopic perspective,real-time T2 spectra monitoring tracked the evolution of FPS at different loading levels,and the geometric mean of the pore structure(T2g)quantitatively described the co-evolution of various pore types.A generalized model was developed to describe coal creep under cyclic loading-unloading,integrating microscopic and macroscopic deformation features and refined using fractal theory.These findings provide theoretical insights and practical guidance for coal extraction and methane management under cyclic loading-unloading creep.
基金partially supported by the following funding sources:The National Natural Science Foundation of China(No.61771084)the Chongqing Graduate Scientific Research Innovation Project(No.CYB21200)。
摘要In high-speed multiuser Time Reversal(TR)downlink systems,the transmission rate is degraded due to the presence of severe inter-user and inter-symbol interference.Moreover,maximizing the weighted sum rate in such systems is a critical objective,since the weighting factors represent the priority of different users in different applications.However,it faces significant challenges as it is an NP-hard and non-convex problem.In order to suppress these interferences and maximize the weighted sum rate,in this paper we present a novel approach for the joint design of the pre-filters.The proposed method applies successive convex approximation to transform the original problem into a Second-Order Cone Programming(SOCP)problem.Then,a low-complexity iterative algorithm is provided to effectively solve the resulting SOCP problem.According to the simulation results,the proposed method reaches a local optimum within a few iterations and demonstrates superior performance in terms of weighted sum rate compared to the current algorithm.
基金supported by the Xinjiang Central Guidance for Local Science and Technology Development Funds Project(Grant No.ZYYD2024QY05)the Hainan Provincial Natural Science Foundation of China(Grant No.323CXTD381)+1 种基金the National Key R&D Program of China(Grant No.2024YFD2101101)within program Grant No.2024YFD2101100.
摘要Chlorophyll(Chl),a natural pigment with broad applications in food systems,faces challenges due to its instability under light exposure.This study explores the relationship between solvent polarity,charge transfer(CT)in Chl self-aggregation,and photostability enhancement.By adjusting ethanol/water ratios(10-100%ethanol),environmental polarity was modulated to investigate its impact on CT dynamics using fluorescence spectroscopy,conductivity analysis,and quantum chemistry calculations.Results demonstrated that higher solvent polarity significantly strengthened CT interactions between Chl molecules,primarily mediated by porphyrin rings,while the hydrophobic phytyl tail influenced aggregate configurations and indirectly modulated CT pathways.Light stability tests revealed that Chl retention in high-polarity solvents(10%-40%ethanol)surpassed low-polarity groups(60%-90%ethanol)by 213.04%and 302.61%on days 4 and 8,respectively,highlighting the critical role of CT-driven aggregation in mitigating photodegradation.Quantum calculations further elucidated that phytyl tail removal altered CT efficiency depending on porphyrin spacing:in'sandwich'dimers,phytyl absence enhanced CT,whereas in'face-to-face'configurations,partial removal optimized electron redistribution.These findings underscore solvent polarity as a key regulator of CT-mediated aggregation,offering a mechanism to stabilize Chl through non-covalent interactions.The study advances the understanding of Chl aggregation mechanisms and proposes physical strategies,such as electric-field-induced CT modulation,to enhance the stability of photosensitive natural pigments in food processing and storage.
基金supported by the National Natural Science Foundation of China(No.32072233)the Natural Science Foundation of Hainan Province(No.323CXTD381).
摘要Chlorophyll(Chl),the most widely distributed natural pigment in nature,is limited in use due to its poor stability.This study refers to the aggregation structure of Chl and carotene(Car)in natural photosynthetic systems,hoping to improve the photostability of Chl by constructing Chl/Car aggregates.The stability protection effect of Car on Chl was explored by designing different ratios of Chl and Car aggregation systems.The configuration of Chl/Car aggregates was optimized through ab initio molecular dynamics,and the aggregation mechanism of the aggregates and the photoprotection mechanism of Chl by Car were elucidated through quantum chemical calculations and wave function analysis.Chl/Car had a 27.22% higher Chl retention rate than free Chl after 7 d of illumination,with a Chl to Car ratio of 1.66:1.A configuration of the Chl/Car aggregates which Car's conjugated olefin chain interacts extensively with the porphyrin ring and bent phytyl chain of Chl made them more stable.The photoprotective mechanism of Car on Chl in the Chl/Car aggregates is elucidated.Car's conjugated polyene chain provides HOMO orbitals to the Chl/Car aggregates.It demonstrated that Car supplies electrons in the low-lying excited states S2 and S4,indicating it is more susceptible to damage,protecting Chl.This research will promote the development of natural color formulas and ensure the health of consumers.
基金partially supported by the National Natural Science Foundation of China(Nos.61271260 and 61301122)the Natural Science Foundation of Chongqing Science and Technology Commission(No.cstc2015jcyjA40050,cstc2014jcyjA40052)+2 种基金Scientific and Technological Research Program of Chongqing Municipal Education Commission(KJ1400405)Research Fund for Young Scholars of Chongqing University of Posts and Telecommunications(A2013-30)the Science Research Starting Foundation of Chongqing University of Posts and Telecommunications(A2013-23).
摘要The security incidents ion networks are sudden and uncertain,it is very hard to precisely predict the network security situation by traditional methods.In order to improve the prediction accuracy of the network security situation,we build a network security situation prediction model based on Wavelet Neural Network(WNN)with optimized parameters by the Improved Niche Genetic Algorithm(INGA).The proposed model adopts WNN which has strong nonlinear ability and fault-tolerance performance.Also,the parameters for WNN are optimized through the adaptive genetic algorithm(GA)so that WNN searches more effectively.Considering the problem that the adaptive GA converges slowly and easily turns to the premature problem,we introduce a novel niche technology with a dynamic fuzzy clustering and elimination mechanism to solve the premature convergence of the GA.Our final simulation results show that the proposed INGA-WNN prediction model is more reliable and effective,and it achieves faster convergence-speed and higher prediction accuracy than the Genetic Algorithm-Wavelet Neural Network(GA-WNN).Genetic Algorithm-Back Propagation Neural Network(GA-BPNN)and WNN.
基金Supported by National Key Research and Development Plan(2016YFD-0100204-8)Special Project for Basic Science and Technology Work(2012FY110203)+3 种基金Special Project for Protection of Crop Germplasm Resources of Ministry of Agriculture(2016NWB037)the Agriculture Research System(CARS-24-A-01)the Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences(CAAS-ASTIP-IVFCAAS)Key Laboratory of Biology and Genetic Improvement of Horticultural Crops,Ministry of Agriculture
摘要Guizhou Province is an important distribution area of wild onion resources,and a large area of wild( Chinese) chives are distributed in Hezhang County. In order to understand and study the distribution of wild chives,the geographical distribution,habitats and climate of wild chives in Hezhang County were investigated,and the main nutrition components of wild chives were analyzed. The results indicated that there were mainly three kinds of wild chives distributed in Hezhang County, including Allium wallichii Kunth., Allium ovalifolium Hand.-Mazz.( tentatively named),and Allium hookeri Thwaites( tentatively named). Among the 17 kinds of amino acids,except for proline,the content of other amino acids in wild chives was higher than that of the cultivated chives( Allaum tuberosum Rottler ex Spreng.). The sugar content of wild chives was significantly lower than the cultivated chives. Among nine trace elements,the manganese,zinc and iron content of A. ovalifolium Hand.-Mazz. were significantly higher than that of the cultivated chives and other wild chives. Among the four kinds of heavy metals,cadmium content in the three kinds of wild chives exceeded the limitation of the national standard,and cadmium content in A. ovalifolium Hand.-Mazz. was significantly higher than that of the others. Arsenic,mercury and lead content in A. ovalifolium Hand.-Mazz. also exceeded the limitation of the national standard. Vitamin C content in leaves and stalk of A. wallichii Kunth. in the original habits was higher than that of the cultivated chives. The biological characteristics and nutrition components of the wild chives from Hezhang County were significantly different from that of the cultivated chives. The collection and preservation of these resources are of great significance to the enriching of diversity of Chinese chive resources and has great development and utilization value to the improvement of nutritional quality of Chinese chives.
基金supported by the National Natural Science Foundation of China[grant number:82360014]the Cuiying Scientific Training Program for Undergraduates of The Second Hospital&Clinical Medical School,Lanzhou University,Lanzhou,China[grant number:CY2023-MS-B05].
摘要N6-methyladenosine (m6A) methylation is the most prevalent and abundant internal post-transcriptional RNA modification in eukaryotic cells, playing an important regulatory role in various biological processes. The biological functions of m6A modification are dynamically and reversibly mediated by methyltransferases (writers), demethylases (erasers), and m6A binding proteins (readers). Acute lung injury (ALI) is a common critical condition characterized by diffuse edema within the pulmonary interstitium and alveoli, and is associated with high morbidity and mortality. Recent studies have identified that aberrant expression of m6A regulators is closely associated with ALI development. This review highlights the progress in research on m6A writers, erasers, and readers in ALI, focusing on their molecular regulatory mechanisms. Elucidating the molecular mechanisms of m6A and its associated proteins in ALI may reveal new therapeutic strategies and targets.