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Exercise training promotes nerve cell repair and regeneration after spinal cord injury 认领 引用 被引量：1
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作者 Tianyu Zhai Shuting Ren +9 位作者 Shenghao Qian Caizhen Shi Bingbing Wang Can Zhang Li Dan Juan Shen Feng Gao Yanling Yang Youlei Li Lin Zhao 《Neural Regeneration Research》 SCIE CAS CSCD 2026年第6期2153-2168,共16页
Spinal cord injury is a severe neurological condition characterized by the permanent loss of nerve cell function and a failure in neural circuit reconstruction-key factors contributing to disability.Therefore,explorin... Spinal cord injury is a severe neurological condition characterized by the permanent loss of nerve cell function and a failure in neural circuit reconstruction-key factors contributing to disability.Therefore,exploring effective strategies to promote the repair and regeneration of nerve cells after spinal cord injury is crucial for optimizing patient prognosis.The purpose of this paper is to conduct an in-depth review of the pathological changes in nerve cells after spinal cord injury and to present the state of research on the role of exercise training in promoting the repair and regeneration of nerve cells after spinal cord injury.In terms of the intrinsic growth capacity of neurons,disruptions in the dynamic balance between growth cones and the cytoskeleton,the dysregulation of transcription factors,abnormal protein signaling transduction,and altered epigenetic modifications collectively hinder axonal regeneration.Additionally,the microenvironment of neurons undergoes a series of complex changes,initially manifesting as edema,which may be exacerbated by spinal cord ischemia-reperfusion injury,further increasing the extent of nerve cell damage.The abnormal proliferation of astrocytes leads to the formation of glial scars,creating a physical barrier to nerve regeneration.The inflammatory response triggered by the excessive activation of microglia negatively impacts the process of nerve repair.Non-invasive interventions involving exercise training have shown significant potential in promoting nerve repair as part of a comprehensive treatment strategy for spinal cord injury.Specifically,exercise training can reshape the growth cone and cytoskeletal structures of neurons,regulate transcription factor activity,modulate protein signaling pathways,and influence epigenetic modifications,thereby activating the intrinsic repair mechanisms of neurons.Moreover,exercise training can regulate the activation state of astrocytes,optimize the inflammatory response and metabolic processes,promote astrocyte polarization,enhance angiogenesis,reduce glial scar formation,and modulate the expression levels of nerve growth factors.It also effectively helps regulate microglial activation,promotes axonal regeneration,and improves phagocytic function,thereby optimizing the microenvironment for nerve repair.In terms of clinical translation,we summarize the preliminary results of new drug research and development efforts,the development of innovative devices,and the use of exercise training in promoting clinical advancements in nerve repair following spinal cord injury,while considering their limitations and future application prospects.In summary,this review systematically analyzes findings relating to the pathological changes occurring in nerve cells after spinal cord injury and emphasizes the critical role of exercise training in facilitating the repair and regeneration of nerve cells.This work is expected to provide new ideas and methods for the rehabilitation of patients with spinal cord injury. 展开更多
关键词 astrocytes axons edema exercise inflammation microglia nerve regeneration neurons oxidative stress spinal cord injury
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Multi-scale coherent interfaces in core-shell Sr0.875La0.1TiO3-based textured ceramics for enhanced high temperature thermoelectric performance 认领 引用 被引量：1
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作者 Zhihao Lou Ziyao Wei +4 位作者 Xiaoyu Xu Ping Zhang Jingji Zhang Jie Xu Feng Gao 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第5期279-289,I0007,共11页
SrTiO3-based thermoelectric ceramics show potential for high-temperature energy harvesting but face challenges from inefficient carrier transport and high thermal conductivity.This work presents a multi-scale struc... SrTiO3-based thermoelectric ceramics show potential for high-temperature energy harvesting but face challenges from inefficient carrier transport and high thermal conductivity.This work presents a multi-scale structural engineering strategy to address these challenges,fabricating textured Sr0.875La0.1Ti O3m Ti/10 wt%Bi2O3(SLTTB)ceramics via plate-like SrTiO3templates.Through this design,the ceramics form a unique core-shell architecture,where template seeds act as growth cores for epitaxially alignedoriented grains,forming coherent interfaces with a precipitate-rich interlayer and a precipitate-free shell.In the interlayer,uniformly distributed“peanut-shaped”Bi-Ti_nO2n-1nanoparticle pairs enhance electron mobility and phonon scattering.The hierarchical microstructure creates multiscale coherent interfaces that reduce electron grain boundary scattering,enabling preferential electron transport pathways parallel to the casting direction.This architecture enables the decoupling of electrical and thermal properties,with a power factor reaching 1815μW/m/K2at 1073 K with thermal conductivity suppressed by interfacial and nanoparticle scattering.Consequently,the SLTTB textured ceramic achieves a notable ZT of 0.64 at 1073 K,a significant enhancement over conventional counterparts.This work demonstrates a multi-scale structural strategy integrating template-induced texture,core-shell design,and nanoscale interface modulation to decouple the electrical and thermal properties of SrTiO3-based materials,and provides a roadmap for tailoring the electrical-thermal transport properties of thermoelectric textured ceramics. 展开更多
关键词 Strontium titanate Thermoelectrics Textured ceramics Core-shell architecture Coherent interfaces
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Dietary supplementation with sodium isobutyrate enhances growth performance and colonic barrier function in weaned piglets via microbiota-metabolite-host interactions 认领 引用 被引量：1
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作者 Xiuyu Fang Zihan Chi +6 位作者 Zhengyi Wang Xinlin Wang Xingrui Qu Shuang Zhang Feng Gao Baoming Shi Xuan Zhao 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2026年第1期404-425,共22页
Background Weaning-induced diarrhoea and growth retardation in piglets are associated with impaired intestinal barrier function and decreased levels of colonic short-chain fatty acids(SCFAs).Although SCFA supplementat... Background Weaning-induced diarrhoea and growth retardation in piglets are associated with impaired intestinal barrier function and decreased levels of colonic short-chain fatty acids(SCFAs).Although SCFA supplementation has been proposed to mitigate these issues,the efficacy and optimal dosage of sodium isobutyrate remain unclear.Results We investigated the effects of sodium isobutyrate supplementation(500,1,000,2,000,and 4,000 mg/kg diet)on weaned piglets(Duroc×Landrace×Yorkshire,28 d of age;n=8).After a 28-d feeding trial,supplementation at 500–2,000 mg/kg significantly improved average daily gain and feed efficiency and reduced diarrhoea frequency,with maximal benefits observed at 1,000 mg/kg(P<0.0001).Additionally,500–1,000 mg/kg sodium isobutyrate supplementation increased the apparent digestibility of crude protein,organic matter,and crude fibre(P<0.05).Serum biochemical parameters were unaffected,although secretory immunoglobulin A(SIgA)levels significantly increased upon supplementation with 500–1,000 mg/kg(P<0.05).16S rRNA gene sequencing indicated that sodium isobutyrate increased the abundance of beneficial colonic microbiota.The 1,000 mg/kg group presented the most pronounced effect,with a significant increase of the relative abundance of Prevotella and the greatest improvement in SCFA concentrations(P<0.05).Metabolomics revealed elevated levels of colonic indole-3-lactic acid and 3-hydroxybutyrate upon supplementation with 1,000 mg/kg(P<0.05).Transcriptomic analyses indicated activation of protein digestion and absorption pathways,and PI3K-Akt signalling,marked by TSG-6 upregulation and the suppression of ISG15 and DDIT4 expression(P<0.05).Supplementation with 1,000 mg/kg was associated with improved intestinal barrier-related markers,including reduced serum D-lactate,diamine oxidase,and lipopolysaccharide levels,increased tight junction protein expression;activation of G protein-coupled receptors;and inhibition of TLR4/MyD88/NF-κB signalling(P<0.05),suggesting enhanced barrier function.Conclusions In conclusion,dietary supplementation with 1,000 mg/kg sodium isobutyrate was associated with improved intestinal morphology,reduced serum permeability,increased expression of tight junction proteins,and enhanced immune function in weaned piglets,suggesting enhanced colonic barrier function and providing dosage guidance and mechanistic insights for future applications. 展开更多
关键词 Colonic barrier function Diarrhoea Intestinal microbiota Sodium isobutyrate Weaned piglets
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Biomedical applications of full-spectrum photoacoustic imaging for wavelengthdependent endogenous molecules 认领 引用 被引量：1
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作者 Liwen Jiang Yuanlin Chen +5 位作者 Pengwei Han Hao Zhang Jingran Shao Zhen Tian Feng Gao Jiao Li 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2026年第4期4-21,共18页
Photoacoustic imaging has emerged as a promising technology in the life sciences,exploiting the relatively weak scattering of sound in biological tissues to overcome the penetration limits inherent in conventional opt... Photoacoustic imaging has emerged as a promising technology in the life sciences,exploiting the relatively weak scattering of sound in biological tissues to overcome the penetration limits inherent in conventional optical imaging.Relying on the photoacoustic effect,this imaging modality enables the identification of a wide range of endogenous molecules by analyzing their unique optical absorption spectra.This review summarizes characteristic molecules commonly employed in photoacoustic imaging and their corresponding biomedical applications across the full spectrum,including key bands such as X-ray,ultraviolet,visible,near-infrared,mid-infrared,terahertz,and microwave.Furthermore,the paper also outlines the main endogenous molecules used in photoacoustic imaging and their successful clinical applications,identifies current challenges in the development of full-spectrum photoacoustic imaging,and offers perspectives on future directions for technological advancement.Continued progress in photoacoustic imaging is expected to broaden its advantages,thereby facilitating advancements in biomedicine. 展开更多
关键词 Photoacoustic imaging light absorption full-spectrum imaging
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Anti-Polyelectrolyte-Effect Hydrogel Unlocks Efficient Uranium Extraction from Concentrated Seawater 认领 引用
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作者 Hui Wang Feng Gao +5 位作者 Taohong Xu Peng Liu Zhanhu Guo Guanbing Zhou Yihui Yuan Ning Wang 《Engineering》 SCIE EI CSCD 2026年第5期198-209,共12页
Uranium extraction from seawater is a promising strategy to alleviate global uranium scarcity,yet its implementation is hindered by extremely low concentrations and complex ionic environments.Concentrated seawater bri... Uranium extraction from seawater is a promising strategy to alleviate global uranium scarcity,yet its implementation is hindered by extremely low concentrations and complex ionic environments.Concentrated seawater brine,a byproduct of salt production and desalination,contains 2-10 times more uranium than natural seawater,yet its high salinity presents additional challenges for extraction.Conventional polyamidoxime(PAO)hydrogels exhibit salt-induced shrinkage,compromising functional group accessibility and adsorption efficiency.Herein,we develop an anti-polyelectrolyte effect hydrogel by composing polyvinylphosphonic acid(PVPA)and the PAO.Under high-salinity conditions,cations and anions accumulate via diffusion around the positively charged amidoxime and negatively charged phosphonic acid groups,weakening interchain electrostatic attractions.This anti-polyelectrolyte effect promotes hydrogel swelling,significantly improving the exposure of binding sites and uranyl ion uptake.The PVPA-PAO hydrogel achieves a uranium adsorption capacity of 43.89 mg·g-1 after 24 days in concentrated natural seawater derived from solar saltworks,significantly surpassing that of previously reported PAO hydrogels(~10 mg·g-1).In addition,it exhibits excellent antibacterial performance,mechanical robustness,and ion selectivity.This work presents an effective strategy for improving uranium recovery from marine resources and advances the comprehensive development and utilization of seawater resources. 展开更多
关键词 Uranium extraction Concentrated seawater Anti-polyelectrolyte effect Functional group accessibility Anti-biofouling
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Microseismic characteristics and settlement analysis of concrete face rockfilldams on deep overburden layers during the fillingprocess 认领 引用
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作者 Haoyu Mao Nuwen Xu +5 位作者 Peiwei Xiao Guo Liao Feng Gao Xiang Zhou Xinchao Ding Biao Li 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第2期1034-1048,共15页
Many hydropower projects have been constructed in Southwest China with the strategic goal of achieving carbon neutrality.Most of these hydropower projects utilize concrete face rockfilldams(CFRDs)built on a deep overb... Many hydropower projects have been constructed in Southwest China with the strategic goal of achieving carbon neutrality.Most of these hydropower projects utilize concrete face rockfilldams(CFRDs)built on a deep overburden layer.The deep overburden layer causes uneven settlement between the overburden layer and the dam,which poses a serious threat to the safety of both the construction and operation of the dam.In this study,microseismic(MS)monitoring technology was employed for the firsttime in the fieldof dam fillingengineering,allowing for the real-time monitoring of microfracture in the bedrock during dam construction.The time-frequency analysis method was used to summarize the MS waveform characteristics induced by dam filling.The fracture mechanism of bedrock was revealed,and the relationships among slope deformation,dam settlement,and MS activity were analyzed.The following research results have been obtained.The MS signal induced by dam fillinghas low energy and amplitude,short duration,and high frequency.The fracture of the bedrock was mainly shear failure.MS monitoring can predict deformation during blasting excavation and capture the large settlement that may occur during dam fillingin advance.Research findingshave demonstrated the significantapplication value of MS monitoring technology in predicting the risk of dam settlement and provide a reference for similar projects. 展开更多
关键词 Concrete face rockfilldam(CFRD) Deep overburden layer Settlement Microseismic(MS)monitoring Dam filling
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Boosting Piezoelectric Voltage Constant in 3D-Interconnected PZNNT Porous Piezoceramics via Pore Architecture Engineering 认领 引用
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作者 Xiaoying Feng Jie Xu +5 位作者 Chenhe Xia Xinyue Tang Ziyao Wei Mupeng Zheng Yudong Hou Feng Gao 《Rare Metals》 SCIE EI CAS CSCD 2026年第3期430-441,共12页
In conventional piezoceramics,the coordinated change between the dielectric constant(εr)and the piezoelectric charge constant(d33)usually limits the piezoelectric voltage constant g33(g33=d33/εr),a... In conventional piezoceramics,the coordinated change between the dielectric constant(εr)and the piezoelectric charge constant(d33)usually limits the piezoelectric voltage constant g33(g33=d33/εr),a critical figure of merit for piezoelectric sensors.In porous piezoceramics(PPCs),air as a secondary phase reduces εr,whereas controlling 3-dimensional(3D)pore structure through processing can enhance ceramic skeleton connectivity,thereby benefiting d33and enabling the decoupling of electrical parameters.In this work,we fabricate PPCs of PZT-PZN-PNN(PZNNT)via the gel-casting method with varying solid contents.The 5-vol%PZNNT 3D-PPC realizes an 84.5%sharp reduction in εrand a 55.2%retention of d33that synergistically elevates g33to 99.7×10-3Vm N-1,which is 3.7 times that of dense ceramic.Experimental and simulation results confirm that the low stiffness and large deformations of porous materials enable both stress absorption and amplification,thereby enhancing the electromechanical conversion efficiency of piezoelectric materials.Ultimately,the fabricated 3D porous piezoceramic demonstrates exceptional electrical output and sensitivity,whereas its low density and acoustic impedance synergistically position it as a highly competitive candidate for hydrophone and sensor applications. 展开更多
关键词 gel-casting piezoelectric sensor piezoelectric voltage constant porous piezoceramics sensitivity
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Excellent superplasticity for lamellar microstructure in nugget of a double-sided friction stir welded Ti-4.5Al-3V-2Mo-2Fe alloy joint 认领 引用
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作者 Peng Han Wen Wang +7 位作者 Jun Cai Jia Lin Hubin Yang Qianzhi Ma Feng Gao Ke Qiao Fengming Qiang Kuaishe Wang 《Metals Advances》 SCIE EI CAS CSCD 2026年第2期110-123,共14页
This study successfully achieved the welding of Ti-4.5Al-3V-2Mo-2Fe alloy using double side-friction stir welding.The microstructure of the nugget was characterized using a scanning electron microscope,electron backsc... This study successfully achieved the welding of Ti-4.5Al-3V-2Mo-2Fe alloy using double side-friction stir welding.The microstructure of the nugget was characterized using a scanning electron microscope,electron backscatter diffraction,and transmission electron microscope.High-temperature tensile tests were conducted to evaluate the superplastic deformation behavior of the nugget at temperatures ranging from 700℃ to 800℃ and strain rates of 1×10-3s-1-3×10-2 s-1.Results revealed that the nugget predominantly consisted of coarseβgrains,a small amount of grain boundaryα,and a large number of lamellarαwithin the coarseβgrains.An excellent superplasticity of 1400% was achieved at 750℃ and 3×10-3s-1 in the nugget.This was mainly because the lamellar microstructure underwent significant dynamic spheroidization during the initial stage of superplastic deformation.During the dynamic spheroidization process,some lamellarαgrains grow abnormally,absorbing a large number of low-angle grain boundaries and thus providing a favorable condition for their subsequent continuous dynamic recrystallization.Meanwhile,the abnormally grownαgrains quickly engulf the β phase,reducing the size and proportion of the β phase in the tensile specimen.These fine grained and moderate proportions of the β phase effectively coordinated the grain boundary sliding at the later stages of superplastic deformation.Therefore,the dynamic spheroidization mechanism in the initial stage of superplastic deformation was continuous dynamic recrystallization,and the superplastic deformation mechanism was continuous dynamic recrystallization coordinated with grain boundary sliding.Based on these findings,a novel method was proposed to enhance high strain rate superplasticity by introducing prestrain to induce continuous dynamic recrystallization in the lamellar microstructure.This approach increased the superplastic elongation of the nugget from 345%to 520%at 750℃ and a high strain rate of 1×10-2s-1.The study offers valuable insights for achieving superior superplastic forming of Ti-4.5Al-3V-2Mo-2Fe alloy joints. 展开更多
关键词 Titanium alloys Lamellar microstructure Superplasticity
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Multi-objective trajectory optimization for spaceborne antennas with nonlinear coupling using hp-adaptive pseudospectral discretization 认领 引用
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作者 Feng GAO Guanghui SUN 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2026年第2期517-530,共14页
Spaceborne antennas are essential for remote sensing,deep-space communication,and Earth observation,yet their trajectory planning is complicated by nonlinear base-manipulator coupling and antenna flexibility.To addres... Spaceborne antennas are essential for remote sensing,deep-space communication,and Earth observation,yet their trajectory planning is complicated by nonlinear base-manipulator coupling and antenna flexibility.To address these challenges,this paper proposes a multi-objective trajectory optimization framework.The system dynamics capture both nonlinear rigid-flexible coupling and antenna deformation through a reduced-order formulation.To enhance discretization efficiency,a predictive-terminal hp-adaptive pseudospectral method is employed,assigning collocation density based on task-phase characteristics:finer resolution is applied to dynamic segments requiring higher accuracy,especially near the terminal phase.This enables efficient transcription of the continuous-time problem into a Nonlinear Programming Problem(NLP).The resulting NLP is then solved using a multi-objective optimization strategy based on the nondominated sorting genetic algorithm II,which explores trade-offs among antenna pointing accuracy,energy consumption,and structural vibration.Numerical results demonstrate that the proposed method achieves a reduction of approximately 14.0% in control energy and 41.8%in peak actuation compared to a GPOPS-II baseline,while significantly enhancing vibration suppression.The resulting Pareto front reveals structured trade-offs and clustered solutions,offering robust and diverse options for precision,low-disturbance mission planning. 展开更多
关键词 hp-adaptive pseudospectral method Multi-objective trajectory optimization Nonlinear dynamics Rigid-flexible coupling Spaceborne antenna Structural vibration suppression
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Expert consensus statement for basic research of animal exercise intervention studies in chronic disease prevention and treatment:A joint position paper of the Exercise Science branch of the Biophysical Society of China and the Metabolism and Genetics branch of the Genetics Society of China 认领 引用
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作者 Yihua Bei Dan Zhong +27 位作者 Junmei Lu Yan Qiu T Scott Bowen Ning Chen Yaoshan Dun Feng Gao Yu Huang Guoping Li Jia Li Jin Li Fangchao Liu Weina Liu Xinran Ma Anthony Rosenzweig Michail Spanos Zhenjun Tian Peng Yin Ru Wang Yao Wang Danyan Xu Lingyan Xu Li Zhang Jihui Zhang Xing Zhang Qiulian Zhou Yuandong Qiao Ming Xu Junjie Xiao 《Journal of Sport and Health Science》 SCIE CAS CSCD 2026年第6期1-37,F0003,共37页
Chronic diseases,broadly defined as long-duration conditions that require sustained medical care and/or limit activities of daily living,are a major problem that threatens human health and imposes large social and eco... Chronic diseases,broadly defined as long-duration conditions that require sustained medical care and/or limit activities of daily living,are a major problem that threatens human health and imposes large social and economic burdens.Physical activity has many beneficial effects for human health and is among the most cost-effective ways to prevent and treat chronic diseases.Animal exercise intervention studies are widely used and provide valuable scientific evidence about the cellular and molecular mechanisms underlying the effects of exercise training in a variety of chronic disease models.This consensus statement will provide expert opinions and recommendations for the appropriate design and application of animal exercise intervention studies and models in fundamental investigations of prevention and treatment of chronic diseases,especially focusing on cardiovascular and cerebrovascular diseases(coronary artery disease and stroke),metabolic diseases(obesity and type 2 diabetes mellitus),chronic respiratory diseases(chronic obstructive pulmonary disease),and neurological diseases(Alzheimer's disease).This statement highlights various exercise models(as determined by frequency,intensity,time,and type of exercise intervention)utilized for each disease.Additionally,it includes a list of functional,structural,biochemical,and disease-specific evaluation metrics of exercise effects,followed by outlined recommendations for the exercise study design and evaluations for the mentioned chronic diseases.This consensus aimed to offer practical recommendations for better design and conduct of fundamental research in animal exercise intervention studies to improve our understanding of the effects of exercise on chronic diseases,and to further develop physical exercise or exercise-mimetic interventions for disease prevention and treatment. 展开更多
关键词 Chronic diseases Physical activity Exercise Animal study
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Stress analysis of crack characteristic of anthracite under dynamic loading 认领 引用 被引量：1
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作者 Yun Bai Feng Gao +3 位作者 Ning Luo Zhizhen Zhang Yue Niu Shanjie Su 《Deep Underground Science and Engineering》 EI CAS CSCD 2026年第1期56-65,共10页
The coal dynamic characteristic stress identification under dynamic load is important for guiding underground mineral mining and predicting underground dynamic disasters.In this article,the dynamic compression test of... The coal dynamic characteristic stress identification under dynamic load is important for guiding underground mineral mining and predicting underground dynamic disasters.In this article,the dynamic compression test of anthracite under five strain rates is carried out,the evolution law of three kinds of crack characteristic stress is analyzed,and a prediction model of the crack characteristic stress threshold considering the strain rate effect is established.Then,the rationality of crack characteristic stress under dynamic loading is discussed from the damage evolution standpoint,and the crack extension response mechanism during dynamic compression of anthracite is discussed.The result shows that the crack characteristic stress threshold is significantly influenced by the strain rate.The three characteristic stress thresholds are positively correlated with the strain rate,but the ratios to the crest stress gradually decrease.The increase in the strain rate strongly contributes to the crack extension behavior of anthracite.In the crack unstable extension phase,because of the increase of the strain rate,anthracite shows more energy dissipation under the same deformation in association with the stress concentration effect and the dynamic strength enhancement effect.The crack propagation rate is increased,the crack propagation path of the section is more complex,and more severe damage occurs before the dynamic failure of anthracite,which leads to even more severe damage. 展开更多
关键词 crack characteristic stress threshold damage evolution prediction model strain rate effect underground dynamic disasters
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Post-stroke rehabilitative mechanisms in individualized fatigue level-controlled treadmill training in rats 认领 引用
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作者 Yuchen Xu Yulong Peng +6 位作者 Yuanfa Yao Xiaoman Fan Minmin Wang Feng Gao Mohamad Sawan Shaomin Zhang Xiaoling Hu 《Neural Regeneration Research》 SCIE CAS CSCD 2026年第10期4924-4932,共9页
Clinically,individualized training improves post-stroke motor function rehabilitation efficiency.However,the mechanisms underlying how individualized training facilitates recovery remain relatively unclear.Here,we exp... Clinically,individualized training improves post-stroke motor function rehabilitation efficiency.However,the mechanisms underlying how individualized training facilitates recovery remain relatively unclear.Here,we explored the cortical and corticomuscular rehabilitative effects of post-stroke motor function recovery during individualized training using a rat model of intracerebral hemorrhage.Forced training or individualized fatigue-controlled training was provided from days 2 to 14 post-stroke.The fatigue-controlled training group exhibited superior motor function recovery and less central fatigue compared with the forced training group.Electroencephalograph power spectrum density slope analysis demonstrated better inter-hemispheric balance in the fatigue-controlled training group than in the forced training group.Directed corticomuscular coherence analysis indicated that training-induced fatigue led to a short-term downregulation of descending directed corticomuscular coherence and an upregulation of ascending directed corticomuscular coherence.In the long term,excessive fatigue hindered the recovery of descending control in the affected hemisphere.In conclusion,the individualized strategy of peripheral fatigue-controlled training achieved better motor function recovery,which may be attributed to the mitigation of central fatigue,optimization of inter-hemispheric balance,and enhancement of descending control in the affected hemisphere.This is the first study to investigate the mechanisms underlying individualized rehabilitative effects at the cortical and corticomuscular levels.Our findings suggest that personalized training protocols that are tailored to manage fatigue levels may substantially enhance post-stroke motor efficiency.They also provide a mechanistic foundation for developing fatigue-monitored,individualized rehabilitation programs in clinical practice. 展开更多
关键词 central fatigue corticomuscular coherence electroencephalography fatigue individualized training interhemispheric balance motor function recovery peripheral fatigue stroke rehabilitation treadmill training
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Reproducible Fabrication of Perovskite Photovoltaics via Supramolecule Confinement Growth 认领 引用
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作者 Xinyi Liu Jin Xie +11 位作者 Ziren Zhou Huijun Lian Xinyuan Sui Qing Li Miaoyu Lin Da Liu Haiyang Yuan Feng Gao Yongzhen Wu Hua Gui Yang Shuang Yang Yu Hou 《Nano-Micro Letters》 SCIE EI CAS CSCD 2026年第2期756-771,共16页
The solution processibility of perovskites provides a costeffective and high-throughput route for fabricating state-of-the-art solar cells.However,the fast kinetics of precursor-to-perovskite transformation is suscept... The solution processibility of perovskites provides a costeffective and high-throughput route for fabricating state-of-the-art solar cells.However,the fast kinetics of precursor-to-perovskite transformation is susceptible to processing conditions,resulting in an uncontrollable variance in device performance.Here,we demonstrate a supramolecule confined approach to reproducibly fabricate perovskite films with an ultrasmooth,electronically homogeneous surface.The assembly of a calixarene capping layer on precursor surface can induce host-guest interactions with solvent molecules to tailor the desolvation kinetics,and initiate the perovskite crystallization from the sharp molecule-precursor interface.These combined effects significantly reduced the spatial variance and extended the processing window of perovskite films.As a result,the standard efficiency deviations of device-to-device and batch-to-batch devices were reduced from 0.64-0.26%to 0.67-0.23%,respectively.In addition,the perovskite films with ultrasmooth top surfaces exhibited photoluminescence quantum yield>10%and surface recombination velocities<100 cm s-1for both interfaces that yielded p-i-n structured solar cells with power conversion efficiency over 25%. 展开更多
关键词 Solar cells Reproducibility Perovskites Space-confined growth Supramolecules
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Magnetic field enhanced electrocatalytic oxygen evolution of CoFe2O4 with tunable oxygen vacancy concentrations 认领 引用
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作者 Xiangyang Zou Ping Guo +2 位作者 Yuanyuan Zhang Feng Gao Ping Xu 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第1期671-677,共7页
Magnetic field-driven spin polarization modulation has emerged as an effective way to boost the electrocatalytic oxygen evolution reaction(OER).However,the correlation among catalyst structure,magnetic property,and ma... Magnetic field-driven spin polarization modulation has emerged as an effective way to boost the electrocatalytic oxygen evolution reaction(OER).However,the correlation among catalyst structure,magnetic property,and magnetic field enhanced-electrochemical activity remains to be fully elucidated.Herein,single-domain CoFe2O4 catalysts with tunable oxygen vacancies(CFO-VO) were synthesized to probe how VO mediates magnetism and OER activity under magnetic field.The introduction of VO can simultaneously modulate saturation magnetization(Ms) and coercivity(Hc),where the increased Ms dominates the magnetic field-enhanced OER activity.Under a 14,000 G magnetic field,the optimized CFO-VO exhibits up to 16.1 % reduction in overpotential and 365 % enhancement in magnetocurrent(MC).Electrochemical analyses and post-OER characterization reveal that the magnetic field synergistically improves OER kinetics through lattice distortion induction,magnetohydrodynamic effect,and spin charge transfer effect.Importantly,the magnetic field promotes additional Co3+ generation to compensate for charge imbalance caused by VO filling,maintaining dynamic equilibrium of VO and effective reactant adsorption-conversion processes.This work unveils the synergistic mechanism of VO and magnetic parameters for enhancing OER performance under the magnetic field,providing new insights into the design of high-efficiency spinregulated OER catalysts. 展开更多
关键词 Spinel oxide Oxygen vacancy Magnetic field Magnetic property Oxygen evolution reaction
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Stone-like fruit is associated with reduced herbivory and enhanced reproductive success in an alpine legume(Phyllolobium heydei) 认领 引用
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作者 Feng Gao Quan Yuan +2 位作者 Hong-Sen Hua Hao-Ran Sun Yang Dong 《Plant Diversity》 SCIE CAS CSCD 2026年第4期851-854,共4页
Camouflagehas evolved independently across the tree of life as a defensive strategy to avoid predator attacks(Lev-Yadun et al.,2004;Niu et al.,2018).Although widespread in animals,camouflageis relatively rare in plant... Camouflagehas evolved independently across the tree of life as a defensive strategy to avoid predator attacks(Lev-Yadun et al.,2004;Niu et al.,2018).Although widespread in animals,camouflageis relatively rare in plants(Niu et al.,2018). 展开更多
关键词 Fruits Camouflage Adaptive evolution Phyllolobium heydei Anti-predator defenses Reproductive success
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BMPER induces the adipogenic differentiation of fibro/adipogenic progenitors and promotes intramuscular fat deposition in chickens 认领 引用
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作者 Ying Liu Jianliang Liu +5 位作者 Xuan Sun Xiuze Zhang Tong Xing Lin Zhang Feng Gao Liang Zhao 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2026年第4期2377-2395,共19页
Background Fibro-adipogenic progenitors(FAPs)serve as the developmental origin of intramuscular adipocytes in skeletal muscle.Enhancing their adipogenic transition could increase intramuscular fat(IMF)deposition,there... Background Fibro-adipogenic progenitors(FAPs)serve as the developmental origin of intramuscular adipocytes in skeletal muscle.Enhancing their adipogenic transition could increase intramuscular fat(IMF)deposition,thereby improving meat flavor in chickens.However,critical aspects of FAPs including their cellular composition,dynamic changes during skeletal muscle growth,and associated regulatory mechanisms remain poorly understood.Therefore,we comprehensively characterized FAPs in Langshan chickens from d 1 to d 98 using both in vivo and in vitro approaches combined with single-nucleus RNA sequencing(snRNA-seq)analysis.Results Our analysis of IMF contents and adipogenesis-related gene expression in the pectoralis major muscle of Langshan chickens revealed that the adipogenic properties of FAPs peaked at d 1,reached its lowest point at d14,and subsequently increased until d 98.The snRNA-seq analysis successfully identified the population of FAPs along with their 5 subtypes including the pre-adipogenic,adipogenic,and fibrotic FAPs.The ratio of the pre-adipogenic subtype decreased from d 14 to d 98,which was reversely correlated with the changes of the adipogenic subtype,suggesting a differentiating process.Furthermore,RNA velocity and pseudo-trajectory analysis revealed that the initial FAPs had superior fibrotic capacity but decreased over time which contrasted with their enhanced adipogenic capacity with development.Notably,BMPER was identified as an important regulator for the adipogenic differentiation of FAPs,which was also confirmed by in vitro over-expression studies.In addition,the expression of BMPER in the adipogenic portion of FAPs was found to be highly conserved across human and mouse skeletal muscles.Conclusions Our study provides the first comprehensive atlas of FAPs in the skeletal muscle of chickens and identifies BMPER as a key regulator for the adipogenic differentiation of FAPs.The findings will not only provide novel targets for breeding chickens with high IMF content but also offer significant insights into understanding the cell fate decision of FAPs under both physiological and pathological conditions across species. 展开更多
关键词 Adipogenic progression BMPER Broilers Fibro/adipogenic progenitors snRNA-seq
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Full-physical simulation method based on disturbance moment identification for space dexterous operations 认领 引用
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作者 Zhicheng Yuan Jun He +1 位作者 Xianxing Shen Feng Gao 《ENGINEERING Mechanical Engineering》 SCIE CAS CSCD 2026年第2期1-17,共17页
Space manipulators are crucial for conducting various space missions.To accurately simulate these operations on Earth,this paper presents a full-physical simulation system and corresponding method based on disturbance... Space manipulators are crucial for conducting various space missions.To accurately simulate these operations on Earth,this paper presents a full-physical simulation system and corresponding method based on disturbance moment identification,addressing the issue of incomplete gravity unloading in space dexterous operations.Full-physical simulation is the comprehensive modeling of real-world physical interactions such as motion,forces,and collisions in a virtual environment with high fidelity and accuracy.The system’s hardware configuration is introduced first.Then an innovative full-physical method is proposed mainly consisting of the modeling and optimization of disturbance moment(force).The disturbance moment(force)model is optimized to enhance full-physical simulation accuracy.The control framework gives the system framework and signal flows.Numerical simulations are done to verify the optimization process.Interior point method is utilized to decrease the disturbance moment enormously and to reduce the largest joint moment significantly.Multi-objective particle swarm optimization is then implemented to achieve optimal unloading forces.Finally,experiments confirm the effectiveness of the proposed fullphysical methodology from two aspects:the verification of the identification method and that of optimization method. 展开更多
关键词 disturbance moment full-physical simulation multi-objective optimization MOPSO particle swarm optimization space dexterous operation
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From Stress Redistribution to Energy Accumulation:Lateral Pressure-Driven Chain Evolution in Gas-Bearing Coal 认领 引用
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作者 Wenqi Zheng Feng Gao +6 位作者 Hanpeng Wang Xin Wang Bing Zhang Yue Niu Wei Wang Li Ming Chunbo Zhou 《Fluid Dynamics & Materials Processing》 EI 2026年第4期172-194,共23页
As coal extraction advances to greater depths,a refined understanding of the coupled evolution of involved physical effects and mechanisms in gas-bearing coal under excavation-induced disturbances becomes indispensabl... As coal extraction advances to greater depths,a refined understanding of the coupled evolution of involved physical effects and mechanisms in gas-bearing coal under excavation-induced disturbances becomes indispensable.In this context,“chain evolution”characterizes the progressive and interdependent interplay among stress redistribution,damage propagation,and seepage adjustment.Building upon a seepage–stress–damage coupling model for gas-bearing coal,and supported by triaxial compression tests for validation,this study explores multifield evolution during roadway excavation across lateral pressure coefficients(ξ)of 0.5,0.8,1.0,1.2,and 1.5.The results reveal that the lateral pressure coefficient fundamentally regulates both the orientation and intensity of this coupled process by reshaping the initial stress regime and associated unloading constraints.At relatively low values(ξ1.2),damage localization and permeability enhancement are concentrated in the roof and floor,accompanied by pronounced vertical energy accumulation.These findings underscore that the lateral pressure coefficient not only governs the spatial distribution of individual physical fields but also orchestrates the pathways of their coupled evolution.The study thus provides a robust,mechanism-oriented basis for optimizing support design and implementing targeted hazard mitigation strategies in deep gas-bearing coal seams. 展开更多
关键词 Deep mining lateral pressure coefficient chained multi-field evolution differentiated hazard prevention numerical simulation
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The environmental pollutants of arsenic and microplastics mediating soil microbiota shift aphid growth in tobacco 认领 引用
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作者 Yuan Zhang Mengting Wang +4 位作者 Hu Li Feng Gao Yufang Meng Jinhong Zhou Zihua Zhao 《Ecological Frontiers》 CSCD 2026年第2期728-734,共7页
Environmental pollutants are ubiquitous and persistent in soil,water,and air,posing serious threats to biodiversity,eco-logical functions,and human health.The wide application of agricultural chemicals has led to the ... Environmental pollutants are ubiquitous and persistent in soil,water,and air,posing serious threats to biodiversity,eco-logical functions,and human health.The wide application of agricultural chemicals has led to the release of large amounts of environmental pollutants,which have driven a rapid shift in ecological function via mediating microbiota composition in agroecosystems.In this study,we employed 16S rRNA amplicon sequencing,coupled with phenotype determination of tobacco(Nicotiana tabacum)and aphid(Myzus persicae),to explore the multi-trophic responses of a soil microbiome-tobacco-aphid system to arsenic(As)and microplastics(MPs)stress.Soil residues of As and MPs signif-icantly reduced the species diversity of soil microorganisms and led to a shift in function of microbial community.No-tably,the relative abundances of specific taxa,such as Gemmatimonas and Edaphobaculum,increased following As and MPs exposure,whereas Aquicella and Phycicoccus exhibited a significant decline in contrast.Furthermore,MPs increased the size of tobacco leaves and stem circumference.However,the growth rate of tobacco height significantly decreased with MPs residues in the soil.As exposure reduced the size and number of effective tobacco leaves.The behavioral ex-periment revealed that aphids were attracted to As-stressed tobacco leaves more than to the control.Interestingly,M.persicae exhibited enhanced growth and reproduction on As-stressed leaves,while showing a partially adverse re-sponse to MPs exposure.Therefore,As exposure significantly promoted aphid population growth and potential outbreak risk.Consequently,environmental pollutants affect the complex ecological network among microorganisms,plants,and insects,and pose potential threats to the structural stability and functional integrity of agricultural ecosystems. 展开更多
关键词 Arsenic Microplastics Soil microbiome Tobacco Aphid
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Double ionization of oxygen molecules in counter-rotating two-color elliptical polarization fields 认领 引用
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作者 Feng Gao Xiaolong Lu +3 位作者 Jun Liu Zifeng Wang Jiacheng Mao Peipei Xin 《Communications in Theoretical Physics》 SCIE CAS CSCD 2026年第4期108-116,共9页
The classical ensemble model(CEM)was applied to study the double ionization(DI)yield and correlated dynamics of electron pairs during non-sequential double ionization(NSDI)of oxygen molecules exposed to a counter-rota... The classical ensemble model(CEM)was applied to study the double ionization(DI)yield and correlated dynamics of electron pairs during non-sequential double ionization(NSDI)of oxygen molecules exposed to a counter-rotating two-color elliptically polarized(TCEP)laser field.Numerical simulations revealed a gradual reduction in the DI yield with increasing angle between the major axes of the two elliptically polarized laser components.This angular dependence arises from asymmetric suppression effects that the laser field exerts on the potential barrier of the diatomic molecule,with larger angles decreasing the efficiency of the barrier suppression.Concurrently,as molecular orientation angles increase,the increased travel time of the rescattering electron enhances recollision energies,thereby shifting the joint temporal distribution of ionization and recollision events toward diagonal alignment and altering the dominant NSDI pathways in oxygen molecules. 展开更多
关键词 non-sequential double ionization counter-rotating TCEP laser fields diatomic molecule
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