期刊文献+
任意字段
题名或关键词
题名
关键词
摘要
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息
共找到756篇文章
< 1 2 … 38 >
每页显示 20 50 100
已选0条
引用分析
参考文献
引证文献
 统计分析
检索结果
已选文献
显示方式：
Progress in shock wave diagnostic technology based on velocity interferometers for laser inertial confinement fusion 认领 引用
1
作者 Feng Wang Yulong Li +5 位作者 Zanyang Guan Xiaoshi Peng Xiangming Liu Dong Yang Jiamin Yang Zongqing Zhao 《Matter and Radiation at Extremes》 SCIE EI CAS CSCD 2026年第2期1-13,共13页
Laser-driven inertial confinement fusion(ICF)is an important experimental platform for high-energy-density physics research under extreme conditions.In ICF research,high-quality shock waves are key to fusion energy re... Laser-driven inertial confinement fusion(ICF)is an important experimental platform for high-energy-density physics research under extreme conditions.In ICF research,high-quality shock waves are key to fusion energy release.The velocity interferometer system for any reflector(VISAR)is the most important diagnostic technique for measuring quantities such as shock wave and particle velocities with high precision and high spatiotemporal resolution.This paper provides a detailed introduction to the various configurations of VISAR on 10 and 100 kJ-level laser facilities in China,including Line VISAR,Dual-Axis VISAR,Wide-Angle VISAR,and Compressed Ultrafast Photography-VISAR.Recent advances and applications of VISAR diagnostics at these laser facilities are presented,and the future trend of development of high-spatiotemporal-resolution velocity diagnostic technology is described. 展开更多
关键词 laser inertial confinement fusion high energy density physics velocity interferometer system particle velocities velocity interferometer diagnostic technique shock wave diagnostic technology shock waves
暂未订购 下载PDF
Using Immune Clusters for Classifying Heterogeneity of Immunity in Healthy Adults 认领 引用
2
作者 Xiao-hui Wu Yi Huang +4 位作者 Si-yu Zou Kai-shan Jiang Shi-ji Wu Hong-yan Hou Feng Wang 《Current Medical Science》 SCIE CAS CSCD 2026年第2期367-381,共15页
Objective Quantification of immunity is a challenge in clinical practice due to the complexity and heterogeneity of immune cells.This study aimed to establish comprehensive reference ranges for immune indicators and c... Objective Quantification of immunity is a challenge in clinical practice due to the complexity and heterogeneity of immune cells.This study aimed to establish comprehensive reference ranges for immune indicators and characterize immune heterogeneity in healthy adults.Methods A total of 115 healthy adults aged 1865 years were enrolled.Sixty immune indicators encompassing natural immunity(NK cells,monocytes,dendritic cells,myeloid-derived suppressor cells),cellular immunity(T cells,regulatory T cells,T follicular helper cells,T helper cells),and humoral immunity(B cells),along with nutritional and metabolic indicators,were simultaneously detected.Flow cytometry was used to measure the number,phenotype,and functional subsets of immune cells.Unsupervised k-means clustering was performed to identify immune subtypes.RNA-sequencing was conducted on representative individuals from each cluster for transcriptomic validation.Results The reference ranges for 60 immune indicators were established,with over half(38/60)exhibiting coefficient of variation>30%,indicating substantial heterogeneity.Gender differences were minimal,whereas age-related changes were pronounced in adaptive immune cells.Specifically,human leukocyte antigen DR-positive(HLA-DR+)T cells(%)increased from 20.76%±7.75%(1830years)to 30.06%±10.82%(5165 years,P=0.001),while CD45RA+regulatory T(Treg)cells(%)and naive CD8+T cells(%)decreased progressively with age(P<0.001).Correlation analysis between immune cells and routine laboratory indicators revealed that nutritional indicators like albumin(ALB)were positively correlated with the number of immune cells such as CD8+T cells,while lipid metabolism indicators like low-density lipoprotein(LDL)were negatively correlated with T helper cell differentiation(P<0.01).Clustering analysis identified three distinct immune subtypes:"potential type"(26.1%,n=30)characterized by high naive T cells(44.91%±9.88%CD4+T cells,33.86%±13.82%CD8+T cells)and CD1c-positive myeloid dendritic cells(CD1c+mDCs)(45.17%±11.58%);"effector NK type"(34.8%,n=45)with elevated NK cell count(704.22±280.79 cells/μL)and cytotoxic function(93.16%±2.38%perforin+NK cells);and"effector T type"(39.1%,n=40)distinguished by increased HLA-DR+T cells(19.48%±7.1%CD4+T cells,45.11%±10.92%CD8+T cells)and effector memory(EM)CD4+T cells(37.85%±11.01%).A further RNA-sequencing analysis confirmed the transcriptomic characteristics of different immune subtypes,which was in accordance with phenotype analysis.Specifically,adults in the potential type had strong adaptive immunity;those in the effector NK type showed upregulated NK cell-mediated cytotoxicity;those in the effector T type exhibited enhanced T-helper 1 immune responses.Conclusion This study provides a systematic framework for immunity quantification by establishing reference ranges and classifying healthy adults into three immune subtypes with distinct metabolic and transcriptomic features.These findings could enhance understanding of immune heterogeneity in healthy individuals and guide personalized immune monitoring and intervention strategies in clinical practice. 展开更多
关键词 Immune heterogeneity Healthy adults Immune characteristics Lymphocytes Nutritional indicators Clustering analysis Prediction model
暂未订购 下载PDF
Expert consensus on the detection and clinical application of tumor mutational burden 认领 引用
3
作者 Zhenying Guo Chunwei Xu +168 位作者 Shirong Zhang Yue Hao Xiaotong Hu Ming Zhao Chan Xiang Yingshi Piao Pingli Sun Xueping Xiang Jing Zhao Huanwen Wu Weixing Li Jinpu Yu Jingping Yuan Shuangshuang Wang Cong Wang Yun Gu Bingjian Lv Liping Zhang Yueping Liu Xiaobin Cui Weizhong Gu Yining Li Wei Wang Wenjun Yang Weiguo Long Jingjing Xiang Hong Mou Biao Liu Huajuan Ruan Yubin Wang Yongjie Zhu Feng Wang Zhonghua Wang Xiaomin Feng Xing Liu Peng Li Min Deng Bin Lian Lili Mao Qian Wang Wenxian Wang Zhengbo Song Ziming Li Wenzhao Zhong Zhijie Wang Shengxiang Ren Wenfeng Fang Yongchang Zhang Jingjing Liu Xiuyu Cai Anwen Liu Wen Li Ping Zhan Hongbing Liu Tangfeng Lv Liyun Miao Lingfeng Min Yu Chen Yu Zhang Feng Wang Zhansheng Jiang Gen Lin Long Huang Xingxiang Pu Rongbo Lin Weifeng Liu Chuangzhou Rao Dongqing Lv Zongyang Yu Peng Shen Xiaoyan Li Chuanhao Tang Chengzhi Zhou Junping Zhang Junli Xue Hui Guo Qian Chu Rui Meng Jingxun Wu Rui Zhang Jin Zhou Zhengfei Zhu Yongheng Li Hong Qiu Fan Xia Yuanyuan Lu Xiaofeng Chen Rui Ge Enyong Dai Yu Han Jian Zhang Yinghua Ji Xianbin Liang Hongmei Zhang Xuelei Ma Xuewen Liu Yu Yao Peng Luo Weiwei Pan Fei Pang Fan Wu Dejian Gu Li Wang Liping Wang Youcai Zhu Li Lin Weiwen Li Xinqing Lin Jing Cai Ling Xu Jisheng Li Xiaodong Jiao Kainan Li Jia Wei Huijing Feng Lin Wang Yingying Du Wang Yao Xuefei Shi Xiaomin Niu Dongmei Yuan Yanwen Yao Yinbin Zhang Binbin Song Wenfeng Li Jianfei Fu Hong Wang Mingxiang Ye Dong Wang Zhaofeng Wang Qing Ji Yuan Fang Qing Wei Zhen Wang Bin Wan Donglai Lv Xiaofeng Li Shengjie Yang Jing Kang Jiatao Zhang Chao Zhang Lin Shi Yina Wang Bihui Li Zhang Zhang Ke Wang Zhefeng Liu Nong Yang Lin Wu Xiaobing Chen Gu Jin Zhongwu Li Miao Li Guansong Wang Jiandong Wang Meiyu Fang Yong Fang Xiaojia Wang Jing Chen Yiping Zhang Xixu Zhu Yi Shen Shenglin Ma Biyun Wang Lu Si Yong Song Yuanzhi Lu Aijun Liu Yuchen Han 《Cancer Biology & Medicine》 SCIE CAS CSCD 2026年第2期218-246,共29页
As an emerging biomarker,tumor mutational burden(TMB)has attracted increasing attention from clinicians in predicting the efficacy of tumor immunotherapy.Currently,TMB is detected primarily by whole-exome sequencing o... As an emerging biomarker,tumor mutational burden(TMB)has attracted increasing attention from clinicians in predicting the efficacy of tumor immunotherapy.Currently,TMB is detected primarily by whole-exome sequencing or targeted panel sequencing on high-throughput sequencing platforms.However,the lack of uniformity in detection methods,threshold settings,and reporting formats,as well as the significant differences in TMB values among different cancer types,have hindered the standardized application of this biomarker in clinical practice.This consensus focuses on the definition,standardization of detection,clinical significance,and limitations of TMB,and provides consensus recommendations for the clinical application of TMB in real-world practice in China.This consensus is aimed at helping clinicians and laboratory personnel understand the clinical significance and testing standards of TMB,promoting more accurate interpretation of test results,and improving patient care. 展开更多
关键词 Biomarkers tumor mutational burden tumor immunotherapy targeted panel sequencing whole-exome sequencing
暂未订购 下载PDF
Lignocellulosic biomass conversion into CO and H2 via sunlight-enhanced lattice oxygen recycling in perovskite oxides 认领 引用
4
作者 Xueyuan Wang Yige Guo +6 位作者 Jiaming Cao Yukun Zou Xuke Chen Zhuyan Gao Yuefeng Song Nengchao Luo Feng Wang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第3期237-246,共10页
Converting biomass to syngas(CO+H2)is an accessible way to incorporate renewable carbon into the sustainable chemical industry.However,due to insufficient C–C bond breaking even at high temperature,biomass reformi... Converting biomass to syngas(CO+H2)is an accessible way to incorporate renewable carbon into the sustainable chemical industry.However,due to insufficient C–C bond breaking even at high temperature,biomass reforming produces syngas with a reduced yield accompanied by the formation of tar,char,and complex side-products.Herein,irradiation of perovskite La0.6Sr0.4Co0.2Fe0.75Ru0.05O3-δ(LSCFR)by concentrated sunlight activates thermodynamically stable lattice oxygen,thereby increasing the fraction of activated lattice oxygen from 12%to 43%.This enhanced oxidation ability enables biomass conversion to CO_x in 96%yield alongside H2 production.Sunlight irradiation also facilitates lattice oxygen replenishment via CO2 reduction,allowing dry photoreforming of biomass over LSCFR.In a flow apparatus,the dry photoreforming affords CO and H2 in 80%and 41%yields,respectively,producing 0.15 and 0.06 m~3 of CO and H2 in 20 h.This work reveals the light-responsive oxidation ability of oxides for the sustainable refining of native biomass. 展开更多
关键词 Biomass reforming Photocatalysis Perovskite CO H2
暂未订购 下载PDF
MOF-derived porous Co3O4 nanosheets array assembled on SnO2 nanofibers for humidity-resistant high efficiency acetone detection 认领 引用
5
作者 Jinwu Hu Feng Wang +7 位作者 Jiejie Yu Zijun Hong Wenhui Zhang Hui-Jun Li Zhuangchai Lai Ding Wang Yonghui Deng Guisheng Li 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第5期777-783,共7页
Semiconducting metal oxide based gas sensors exhibit great promise for convenient detection of acetone,a biomarker gas in the exhaled breath of type-I diabetes patients.However,the detection usually suffers the interf... Semiconducting metal oxide based gas sensors exhibit great promise for convenient detection of acetone,a biomarker gas in the exhaled breath of type-I diabetes patients.However,the detection usually suffers the interference from exhaled moisture.To overcome this challenge,in this work,a novel hierarchical heterojunction structure consisting of SnO2nanofiber core and Co3O4nanosheet shell(denoted as SnO2@Co3O4core-shell composite)was proposed for fabricating acetone sensor with excellent humidity resistance.Compared with SnO2nanofibers and Co3O4nanosheets,the SnO2@Co3O4showed the highest sensing response,with a response value(Rg/Ra)of 11.27-50 ppm acetone at 110℃.In addition,the hierarchical SnO2@Co3O4core-shell structure shows fast responseecovery speed(19/43 s),lower detection limit(125 ppb),excellent selectivity and stability in a humidity environment(relative humidity 30%-90%)with a relative change of only 3%.The enhanced gas sensing performance toward acetone is attributed to the synergistic effect between the two components,the unique core-shell hierarchical structure and the rich oxygen vacancy density.Density functional theory calculations reveal that the SnO2@Co3O4has higher acetone adsorption energy than the two components.In addition,a novel SnO2@Co3O4gas sensing module and smart portable sensor device enable efficient real-time monitoring of acetone concentrations on a smartphone via Bluetooth communication. 展开更多
关键词 Hierarchical heterojunction SnO₂nanofiber Co₃O₄nanosheet Acetone detection Metal-organic framework
暂未订购 下载PDF
Stable Integration of Hydrophobic Silica Aerogels into Rubber Latex via Poly(vinyl alcohol)-assisted Aqueous Processing for Thermal Insulating Composites 认领 引用
6
作者 Yan-Chun Han Fang-Shuo Li +8 位作者 Jian-Chao Zhang Quan Wang Guo-Hui Yang Miao Yu Feng Wang Yong-Xin Duan Lu Zong Bo-Xiao Li Jian-Ming Zhang 《Chinese Journal of Polymer Science》 SCIE EI CAS CSCD 2026年第3期821-832,I0016,共12页
Silica aerogels(SAs)impart low density and excellent thermal insulation to polymer systems,yet incorporating hydrophobic SAs into aqueous rubber latex systems remains challenging owing to their poor dispersibility and... Silica aerogels(SAs)impart low density and excellent thermal insulation to polymer systems,yet incorporating hydrophobic SAs into aqueous rubber latex systems remains challenging owing to their poor dispersibility and potential to destabilize the latex.Although previous studies have dispersed SAs in aqueous poly(vinyl alcohol)(PVA),the stability of such dispersions and their effectiveness as bridging media for latex integration have not been thoroughly evaluated,which limits their practical application in latex compounding.This study systematically examined how the surface chemistry governs hydrolytic stability,interfacial behavior,and latex compatibility in PVA-assisted aqueous processing.Two hydrophobic SAs were prepared:ethoxy-modified SA(E-SA)and methyl-modified SA(M-SA).Both initially formed a homogeneous PVA slurry,but E-SA rapidly hydrolyzed its surface—OCH2CH3groups,releasing ethanol,becoming hydrophilic,and undergoing irreversible nanopore collapse.In contrast,M-SA maintains its structural integrity and hydrophobicity because its—Si(CH3)3groups are highly resistant to hydrolysis.This divergence dictates the behavior during latex blending.The ethanol released from E-SA disrupts electrostatic and steric stabilization,inducing latex coagulation,whereas M-SA/PVA dispersions preserve colloidal stability across diverse latex systems.As a practical demonstration,M-SA-reinforced chlorosulfonated polyethylene(CSM)rubber latex composites show more than a 50%reduction in thermal conductivity while maintaining chemical resistance,enabling high-performance insulating protective gloves and coatings.This work establishes a critical link between aerogel surface chemistry and aqueous processing stability,providing a mechanistic foundation for the rational design of water-based rubber/silica aerogel composites and next-generation thermal insulation materials. 展开更多
关键词 Silica aerogel Poly(vinyl alcohol) Rubber latex Surface chemistry Colloidal stability
暂未订购 下载PDF
Metastable heterophase engineering to generate in-plane strain coupled with a built-in electric field enabling efficient hydrogen evolution 认领 引用
7
作者 Selvam Mathi Hamza MHaruna +7 位作者 Zhixiao Zhu James Kumankuma-Sarpong Hao Yang Zeba Khanam Muhammad Mushtaq Feng Wang Zhongmin Wang M.-Sadeeq Balogun 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第7期118-131,I0005,共14页
Strain engineering,interfacial electronic modulation,and bubble management are three powerful descriptors for advancing high-current-density water splitting,yet they are rarely integrated within a single electrode des... Strain engineering,interfacial electronic modulation,and bubble management are three powerful descriptors for advancing high-current-density water splitting,yet they are rarely integrated within a single electrode design.Here,we realize their convergence by constructing amorphous-crystalline(AC)phosphorus-doped NiFe2O4 with heterophase interfaces directly constructed on thiocyanate-etched stainless steel(KSS)(denoted KNP-350-AC).The mismatched phases generate~1.5%in-plane tensile strain that reshapes the d-band configuration of Ni/Fe sites through modulation of the local electronic structure.Meanwhile,strong metal-support interaction modulates the work function and establishes a built-in electric field(BEF),enabling favorable interfacial charge redistribution and optimized adsorption energetics of reaction intermediates,as confirmed by ultraviolet photoelectron spectroscopy(UPS)and density functional theory(DFT).Simultaneously,the rough KSS framework introduces superaerophobic microtextures that accelerate bubble detachment under industrial-level current densities.These coupled effects allow the KNP-350-AC electrode to achieve a hydrogen evolution reaction(HER)overpotential of 280 m V@500 mA cm-2,together with remarkable durability in both alkaline freshwater and seawater.This integrated triple-modulation strategy provides a robust pathway for developing practical HER electrocatalysts for large-scale hydrogen production. 展开更多
关键词 Heterophase strain engineering Built-in electric field modulation Superaerophobic electrode architecture Phosphorus-doped NiFe2O4 Hydrogen evolution reaction
暂未订购 下载PDF
Encapsulation of Antarctic krill oil in alginate-gelatin hydrogel alleviates hyperlipidemia in high-fat-diet fed rats 认领 引用
8
作者 Xuan Ma Yiming Wei +6 位作者 Yi He Chenrui Zhao Qin Chen Bo Liu Tao Wei Wenjie Yan Feng Wang 《Food Science and Human Wellness》 SCIE CAS CSCD 2026年第1期253-262,共10页
Krill oil is effective in reducing blood lipid levels,particularly in individuals with severe hyperlipidemia.However,poor water insolubility and stability limited its usage.This study investigated a method for encapsu... Krill oil is effective in reducing blood lipid levels,particularly in individuals with severe hyperlipidemia.However,poor water insolubility and stability limited its usage.This study investigated a method for encapsulating Antarctic krill oil using alginate(ALG)and gelatin(GLN)to enhance its stability and bioactivity.The encapsulation efficiency,functional group integrity,swelling rate,and lipid-lowering activity were assessed.Results indicated that the optimal encapsulation conditions were identified with an ALG:GLN ratio of 2:1(m/m),coagulation bath of 9%CaCl2,and a nozzle size of 750μm,resulting in 69.34%encapsulation efficiency.Fourier-transform infrared spectroscopy confirmed successful encapsulation.The ALG-GLN shell materials enriched astaxanthin in krill oil and protected it from harsh gastric conditions,enabling targeted intestinal release.In a high-fat diet-induced rat model,krill oil microcapsules significantly reduced triglycerides(TG),total cholesterol(TC),and low-density lipoprotein-cholesterol(LDL-C)levels while increasing high-density lipoprotein-cholesterol(HDL-C)levels compared to unencapsulated krill oil.Additionally,the microcapsules elevated nitric oxide(NO)levels,enhanced superoxide dismutase(SOD)activity,and reduced malondialdehyde(MDA)levels,liver and perirenal fat weight.Therefore,encapsulating Antarctic krill oil in alginate-gelatin hydrogel offers a promising strategy for managing hyperlipidemia and associated metabolic disorders. 展开更多
关键词 Krill oil Microcapsule Alginate,gelatin High-fat diet
暂未订购 下载PDF
HD-ZIP transcription factors:pivotal regulators of plant reproductive development 认领 引用
9
作者 Jiakun Zheng Feng Wang +2 位作者 Yingxiao Mai Xingling Su Rui Xia 《Horticultural Plant Journal》 SCIE CAS CSCD 2026年第4期735-746,共12页
The HD-ZIP gene family,a group of plant-specific transcription factors,plays pivotal regulatory roles in various aspects of plant growth and development.Accumulating evidence has demonstrated the extensive involvement... The HD-ZIP gene family,a group of plant-specific transcription factors,plays pivotal regulatory roles in various aspects of plant growth and development.Accumulating evidence has demonstrated the extensive involvement of HD-ZIP members in regulating reproductive developmental processes.This review systematically summarizes both the structural characteristics of the four HD-ZIP subfamilies(Ⅰ-Ⅳ)and their distinct regulatory roles in plant reproductive development.Recent studies reveal that a conserved HD-ZIPⅠclade serves as a core regulator of key reproductive processes,ranging from spike development in monocots(e.g.,barley Vrs1 and maize GT1)to sex determination in dicots(e.g.,cucumber CmHB40 and persimmon MeGI).Meanwhile,members of other subfamilies(HD-ZIPⅡ-Ⅳ)contribute significantly to diverse reproductive processes including pistil development,floral organ formation,and anther development,among others.This review provides a comprehensive synthesis of HD-ZIP subfamily functions in reproductive development,integrating current knowledge while highlighting critical research gaps.These insights aim to provide theoretical foundations for functional characterization and potential applications of HDZIP reproductive regulators,while advancing our understanding of transcriptional regulation mechanisms in plant reproductive development. 展开更多
关键词 HD-ZIP Transcription factor HD-ZIPⅠ Reproductive development
暂未订购 下载PDF
Recent progress in homogeneous isotropic polymeric turbulence 认领 引用
10
作者 Yi-Bao Zhang Feng Wang Heng-Dong Xi 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第4期483-498,共16页
Minute amounts of long-chain flexible polymers dissolved in fluid flows can significantly alter the flow behaviors,including polymer drag reduction in wall-bounded turbulence and elastic turbulence in low Reynolds num... Minute amounts of long-chain flexible polymers dissolved in fluid flows can significantly alter the flow behaviors,including polymer drag reduction in wall-bounded turbulence and elastic turbulence in low Reynolds number flow.Polymerturbulence interaction,a combination of two fields with many interacting degrees of freedom deviated far from equilibrium,is the key to understanding these intriguing phenomena.In this paper,we review the recent progress of polymer-turbulence interaction in homogeneous isotropic turbulence.For integrity,we first list the governing equations for the flow of a dilute polymer solution.Afterwards,we summarize related theories for the critical length scale below which the energy cascade of Newtonian turbulence is affected by polymers.We then review the theoretical,experimental,and numerical results about the scaling and statistical properties in those affected range of scales.We also include the implications of these results for polymer drag reduction in wall-bounded turbulence.The review has ended up with conclusions from our present understanding and outlooks for future work. 展开更多
关键词 Turbulent flow with polymers Energy cascade Homogeneous isotropic turbulence Polymer drag reduction
暂未订购 下载PDF
SalicS1 FRET sensor enables real-time visualization of salicylic acid dynamics in plant immunity 认领 引用
11
作者 Shengmei Kang Qiyuan Zhang Feng Wang 《Advanced Agrochem》 CAS CSCD 2026年第1期7-9,共3页
SalicS1 is a genetically encoded,ratiometric FRET biosensor that brings salicylic acid(SA)research to the same real-time imaging standard long available for ABA and GA.Built through a modular Golden Gate platform and ... SalicS1 is a genetically encoded,ratiometric FRET biosensor that brings salicylic acid(SA)research to the same real-time imaging standard long available for ABA and GA.Built through a modular Golden Gate platform and informed by NPR-NIMIN structural biology,SalicS1 achieves SA specificity,tunable affinity,reversibility,and non-perturbing expression in Arabidopsis.Using this sensor,pathogen infection,non-adapted fungal challenge,and aphid feeding are shown to elicit spatially propagating SA surges rather than purely local accumulation,revealing a tissue-level organization of immune signaling that bulk assays could not resolve.SalicS1 therefore provides a broadly deployable tool for dissecting the geometry,timing,and genotype dependence of SA-mediated plant defense. 展开更多
关键词 SalicS1 FRET biosensor Salicylic acid dynamics Plant immunity Spatial-temporal imaging
暂未订购 下载PDF
Current status and prospects of guidance techniques for intercepting hypersonic glide vehicles:A review 认领 引用 被引量：1
12
作者 Feng Wang Qiankun Qu +3 位作者 Hao Yang Shou Zhou Xibin Bai Shifeng Zhang 《Defence Technology（防务技术）》 SCIE EI CAS CSCD 2026年第4期241-259,共19页
Hypersonic vehicles present formidable challenges to existing air and missile defence systems due to their extreme velocity,extended-range strike capability,and exceptional maneuverability,driving the need for advance... Hypersonic vehicles present formidable challenges to existing air and missile defence systems due to their extreme velocity,extended-range strike capability,and exceptional maneuverability,driving the need for advanced guidance technologies of interceptors.To address the requirements for defensive operations against hypersonic vehicles,this review focuses on hypersonic glide vehicles(HGVs)as the primary object of study.Their flight characteristics are simulated,and critical interception challenges are analyzed.Then,key technological advancements in interceptor guidance,including midcourse guidance techniques,mid-terminal guidance handover,and terminal guidance laws,are reviewed,providing a comparative analysis of their respective strengths and limitations.Finally,the research summarizes the pivotal scientific problems confronting interceptor guidance technology and provides prospects for the research directions of related technologies.These findings provide a valuable reference for subsequent research on interceptor guidance technology and facilitate the development of next-generation aerospace defence architectures. 展开更多
关键词 Hypersonic glide vehicles interception Trajectory planning Trajectory tracking control Mid-terminal guidance handover Terminal guidance law Cooperative guidance
暂未订购 下载PDF
Pinoresinol diglucoside from Eucommia ulmoides attenuates diabetic cardiomyopathy through suppressing the store-operated calcium entry and downregulating the STIM1/Orai1/NFAT3 signaling pathway 认领 引用
13
作者 Yujie Feng Yanan Mao +6 位作者 Junshuai Li Zhipeng Sun Yingchao Wang Xinru Wang Feng Wang Tiantian Liu Lane Zhang 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2026年第7期849-858,共10页
Pinoresinol diglucoside(PDG),an active component derived from Eucommia ulmoides,exhibits therapeutic effects against apoptosis,inflammation,and hypertrophy,etc.However,whether PDG plays a protective role in diabetic c... Pinoresinol diglucoside(PDG),an active component derived from Eucommia ulmoides,exhibits therapeutic effects against apoptosis,inflammation,and hypertrophy,etc.However,whether PDG plays a protective role in diabetic cardiomyopathy(DCM)is not fully elucidated.This study aimed to investigate the role and potential mechanism of PDG in DCM.The possible mechanism of PDG targeting DCM was identified by network pharmacology,bioinformatics,machine learning and molecular docking methods.The heart function of mice was evaluated using echocardiography.The pathological changes in the heart of mice were detected using H&E staining.Changes of Ca2+fluorescence intensity values in H9c2 cells were assessed by confocal microscopy.Apoptosis was evaluated by TUNEL staining and flow cytometry.The expression of DCM-related genes and proteins,both in vivo and in vitro,was examined by qRT-PCR and Western blot.The results showed that PDG effectively improved the cardiac function and suppressed cardiac hypertrophy,inflammation,and cardiomyocyte apoptosis caused by DCM.Intriguingly,molecular docking results revealed that the therapeutic effect of PDG on DCM was associated with stromal interaction molecule 1(STIM1),calcium release-activated calcium channel protein 1(Orai1),and nuclear factor of activated T-cells 3(NFAT3)signaling.Consistently,animal experiments results indicated that PDG significantly downregulated the expression of STIM1,Orai1,NFAT3 at the protein level,as well as the associated store-operated calcium entry(SOCE).Therefore,our findings revealed that PDG can alleviate cardiac hypertrophy,inflammation and apoptosis in DCM by downregulating the STIM1,Orai1,and NFAT3 signaling molecules.Thus,PDG may be a promising therapeutic candidate for treating DCM. 展开更多
关键词 Pinoresinol diglucoside(PDG) Diabetic cardiomyopathy(DCM) Store-operated calcium entry(SOCE) STIM1/Orai1/NFAT3 signaling pathway Cardiac hypertrophy Inflammation and apoptosis
暂未订购 下载PDF
Evolutionary plasticity of MADS-box genes in ornamental plants:from floral development to horticultural improvement 认领 引用
14
作者 Xinyi Zhou Meiyi She +10 位作者 Feng Wang Xiaojun Chang Biwei Hong Zhengjia Wang Giorgio Perrella D.Blaine Marchant Qiaomei Wang Kejun Cheng Zhonghua Chen Xiaohui Wen Liangsheng Zhang 《Horticultural Plant Journal》 SCIE CAS CSCD 2026年第8期1729-1746,共18页
The MADS-box gene family,particularly the ABCE-class genes,plays a pivotal role in regulating floral development and reproductive processes in angiosperms.Expansion of the MADS-box gene family through ancient whole-ge... The MADS-box gene family,particularly the ABCE-class genes,plays a pivotal role in regulating floral development and reproductive processes in angiosperms.Expansion of the MADS-box gene family through ancient whole-genome duplications and lineage-specific duplication events has generated extensive regulatory flexibility across flowering plants.This review summarizes current findings on the evolutionary expansion and functional diversification of MADS-box genes,with a focus on the evolution of the ABCE-class in ornamental plants.We highlight how differential gene retention,expression divergence,and functional specialization have shaped the remarkable morphological diversity of floral organs across flowering plants.Comparative analyses across angiosperms reveal a lineage-dependent distinction between phylogenetic A-class genes and the developmental A-function:while AP1 represents the canonical A-class gene in core eudicots,AGL6-like genes fulfill ancestral A-function roles in early-diverging angiosperms,magnoliids,and monocots.Lineage-specific expansion and rewiring of ABCE gene networks,as observed in Orchidaceae,Asteraceae,and Rosaceae,have enabled reassembly of MADS-box protein complexes and rebalancing of expression domains,driving innovative floral forms.Beyond floral development,numerous MADS-box genes have diversified to function in flowering-time regulation and environmental stress responses,highlighting their broader adaptive significance beyond reproduction.This review provides an integrated evolutionary and functional perspective on MADS-box genes plasticity,and offers valuable insights for ornamental plant breeding and horticultural improvement. 展开更多
关键词 ABCE model MADS-box Gene family expansion Gene function divergence Flower adaptability Biotic and abiotic stress
暂未订购 下载PDF
A novel approach to simultaneously enhancing the mechanical properties and thermal conductivity of magnesium alloys:Heterogeneous microstructures 认领 引用
15
作者 Wenyuan Cong Feng Wang +5 位作者 Xudong Du Zhi Wang Le Zhou Ziqi Wei Pingli Mao Jian Jiao 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2026年第3期580-595,共16页
The application of magnesium alloys is hindered by the inherent contradiction between mechanical performance and thermal conductivity.Achieving simultaneous enhancement of both properties is crucial for broadening the... The application of magnesium alloys is hindered by the inherent contradiction between mechanical performance and thermal conductivity.Achieving simultaneous enhancement of both properties is crucial for broadening their applications.In this study,Mg-5Zn-xCu-0.5Zr(x=0,0.5,1,2)alloys were fabricated using semi-solid rheo-diecasting(RDC).The microstructure was characterized via OM,SEM,XRD,TEM and EBSD,and its influence on mechanical properties and thermal conductivity was analyzed.The results show that adding Cu refines the grain size,induces the formation of the MgZnCu phase,and reduces solidification shrinkage defects.The RDC Mg-5Zn-xCu-0.5Zr alloy features a heterogeneous microstructure comprising primaryα-Mg(α1)with low solute content,secondaryα-Mg(α2)with high solute atom content,and intergranular second phases.This heterogeneous structure synergistically enhances both mechanical properties and thermal conductivity.Specifically,α1 grains and the MgZnCu phase reduce lattice distortion,thereby improving thermal conductivity,whileα2 generates more dislocations during tensile deformation,contributing to enhanced mechanical properties.Additionally,a small amount of MgZnCu phase contributes to simultaneous improvements in both properties.However,excessive MgZnCu phase can lead to stress concentration due to dislocation pile-up,causing fracture and degrading mechanical properties.Among the alloys studied,the Mg-5Zn-1Cu-0.5Zr alloy exhibits the best combination of mechanical and thermal properties,with a tensile strength of 221 MPa,yield strength of 109 MPa,elongation of 5.72%,and thermal conductivity of 113.8 W/(m·K).This demonstrates the successful simultaneous enhancement of both mechanical and thermal properties in magnesium alloys. 展开更多
关键词 Magnesium alloys Semi-solid rheo-diecasting Tensile properties Thermal conductivity
暂未订购 下载PDF
Functional food potential of Cornus officinalis for liver health:mechanistic evidence and perspectives 认领 引用
16
作者 Bo Liu Yi He +7 位作者 Xuan Ma Chenrui Zhao Qin Chen Yundan Li Jiangying Heng Yu Zhang Jing Jin Feng Wang 《Food Science and Human Wellness》 SCIE CAS CSCD 2026年第2期573-589,共17页
Liver diseases remain a global health crisis,with limited safe therapeutic options.Cornus officinalis,a traditional medicinal-edible plant,has demonstrated significant hepatoprotective potential.This review systematic... Liver diseases remain a global health crisis,with limited safe therapeutic options.Cornus officinalis,a traditional medicinal-edible plant,has demonstrated significant hepatoprotective potential.This review systematically summarizes its liver-protective mechanisms and explores its potential as a functional food.Data were collected from scientific databases such as Pub Med,Science Direct,Elsevier,Google Scholar,and relevant literature.Key bioactive compounds—including iridoids,polyphenols,and polysaccharides—contribute to hepatoprotection by mitigating oxidative stress,inflammation,steatosis,apoptosis,and by regulating gut microbiota.As critical quality markers,iridoids exhibit suboptimal bioavailability,necessitating targeted technological interventions—nanoencapsulation for liver-specific delivery and microbial fermentation for controlled aglycone conversion are proposed to enhance their pharmacokinetic properties and bioactivity.Future research could adopt encapsulation and fermentation technologies for C.officinalis processing,aiming to develop targeted functional food products with enhanced bioactivity of its active components.This review,for the first time,establishes a“component-pathway-integration”model,providing a theoretical framework for evidence-based CO-derived functional food development and highlighting the need for further research on iridoid metabolic transformation to advance liver health management. 展开更多
关键词 Cornus officinalis Hepatoprotective effect Mechanism of action Functional food
暂未订购 下载PDF
Predicting nitrogen surplus in agricultural lands of China using a hybrid machine learning approach with smaller datasets and fewer features 认领 引用
17
作者 Hao Wang Gaofei Yin +8 位作者 Hongda Wen Feng Wang Ziwei Yang Xueying Sun Xulin Zhang Huiqing Jiao Mengyu Zhai Wenchao Li Hongbin Liu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第4期743-753,共11页
Global nitrogen pollution in agricultural lands poses a major environmental challenge,complicating both assessment and mitigation of nitrogen surplus.Nitrogen surplus(NS)is a critical indicator for evaluating nitrogen... Global nitrogen pollution in agricultural lands poses a major environmental challenge,complicating both assessment and mitigation of nitrogen surplus.Nitrogen surplus(NS)is a critical indicator for evaluating nitrogen use efficiency.However,traditional NS estimation methods often require extensive data,which are difficult to obtain in data-scarce regions.In this study,a BN-ML NS prediction model was developed by coupling Bayesian Networks(BN)and Machine Learning(ML)using long-term monitoring data(including climate,soil,and crops)from 2000 to 2019 in China.The key findings are as follows:Nitrogen fertilizer application rate(NR)is the dominant factor influencing NS across the seven regions;however,due to differences in climate,cropping patterns,and soil types,the impact of NR exhibits spatial heterogeneity;The BN-ML model demonstrates strong predictive performance,with R2values exceeding 0.9;compared to traditional NS prediction models,the BN-ML model maintains high accuracy using only half the number of features(e.g.,NR,Yield)and fewer than 120 data points;when validated at the small watershed scale,the model achieved over 80%prediction accuracy.By enabling reliable NS prediction with limited data,the proposed model supports more targeted and sustainable nitrogen management.It can assist national and regional authorities in identifying high-risk areas,optimizing fertilizer use,and formulating region-specific agricultural strategies. 展开更多
关键词 Bayesian network model Extreme gradient boosting Nitrogen management
暂未订购 下载PDF
Synergistic action of60Co-γirradiation on quality preservation of fresh-cut lotus root:microbial control and targeted polyphenol oxidase suppression 认领 引用
18
作者 Dongjie Liu Shihui Zhang +4 位作者 Feng Wang Bifeng Lan Xiaomei Wen Gengsheng Xiao Lukai Ma 《Food Innovation and Advances》 2026年第2期145-152,共8页
Fresh-cut lotus root is highly susceptible to quality deterioration,primarily due to enzymatic browning and microbial growth.This study investigated the efficacy and mechanism of 60Co-γirradiation in preserving th... Fresh-cut lotus root is highly susceptible to quality deterioration,primarily due to enzymatic browning and microbial growth.This study investigated the efficacy and mechanism of 60Co-γirradiation in preserving the quality of fresh-cut lotus root.The results demonstrated that irradiation effectively controlled total bacterial numbers within 5 log10 CFU/g throughout the storage period.Irradiation significantly inhibited browning,reducing the browning index by 19.6%,25.3%,and 28.6%at 1,2,and 3 kGy,respectively,compared to the control.This inhibitory effect was attributed to the delayed degradation of total phenolics and the suppressed accumulation of soluble quinones,the direct browning precursors.Irradiation induced a dose-dependent inhibition of polyphenol oxidase(PPO)activity,with the 3 kGy treatment exerting the strongest suppressive effect;however,the activities of phenylalanine ammonialyase(PAL)and peroxidase(POD)remained unaffected.Circular dichroism(CD)and fluorescence spectroscopy revealed three kGy irradiation induced rearrangements in the secondary structure,and disruption of the tertiary structure of PPO.Specifically,CD analysis definitively characterized conformational changes in PPO,showing a dramatic reduction in theα-helix content from 35.4%to 18.4%.Meanwhile,fluorescence spectra of PPO exhibited a 12 nm redshift accompanied by significant fluorescence quenching.This phenomenon provides direct evidence that the enzyme's tertiary structure was disrupted,which in turn lead to the exposure of its hydrophobic core and ultimately resulted in functional inactivation.60Co-γirradiation is a highly effective technology for maintaining the quality of fresh-cut lotus root,primarily through direct microbial inactivation and the suppression of the PPO-mediated browning pathway. 展开更多
关键词 microbial control enzyme inhibition Co irradiation structural disruption enzymatic browning polyphenol oxidase lotus root quality preservation
暂未订购 下载PDF
Oceanographic significance of planktonic foraminiferal assemblages in the northwest Indian Ocean-Basin-Ridge system under monsoon influence 认领 引用
19
作者 Feng WANG Yunhai LI +6 位作者 Xuan DING Mingjiang CAI Zhikun LAI Jian CHEN Pengfei SHEN Liang WANG Xiang YE 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2026年第3期990-1004,共15页
Planktonic foraminifera in ocean sediments serve as unique paleoenvironmental recorders,and their distribution and diversity are affected by environmental factors.The northwest Indian Ocean,influenced by monsoons and ... Planktonic foraminifera in ocean sediments serve as unique paleoenvironmental recorders,and their distribution and diversity are affected by environmental factors.The northwest Indian Ocean,influenced by monsoons and ocean-basin-ridge systems,is a key research area in this regard.However,few studies have focused on the foraminiferal distribution in surface sediments.We analyzed 60 surface sediment samples in April 2023,from which 11 genera and 32 warm-water species were identified.The distribution was primarily controlled by depth-dependent carbonate dissolution,temperature-salinity gradients,and monsoon-driven hydrography.Four distinct assemblages were identified:the Arabian Basin assemblage(dominated by Globorotalia cultrata)demonstrates strong influence from the Arabian Sea high-salinity water and winter monsoon circulation;the Carlsberg Ridge assemblage(dominated by G.cultrata,Globorotalia tumida)exhibits depth-controlled productivity signatures;the Carlsberg Ridge Flanks assemblage(mainly including Globigerinita glutinata,G.cultrata,Globigerinoides ruber)reflects monsoon-induced mixing processes;and the Somali Basin assemblage(including mainly G.cultrata,Pulleniatina obliquiloculata,G.tumida)shows clear imprints of summer monsoon upwelling.Carbonate dissolution in the Somali Basin is strongest,followed by Arabian Basin,the Carlsberg Ridge showed the weakest dissolution.Based on planktonic foraminiferal abundance,fragmentation rate,CaCO3 content,and dissolution susceptibleesistant species,the carbonate lysocline and compensation depth were estimated at~3700 and~4800 m,respectively. 展开更多
关键词 northwest Indian Ocean surface sediment planktonic foraminifera assemblage
暂未订购 下载PDF
已选0条
引用分析
参考文献
引证文献
 统计分析
检索结果
已选文献
上一页 1 2 … 38 下一页 到第 页
在线咨询 使用帮助 返回顶部 意见反馈