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Mineral resources of Asia continent:Resource endowment,mining industry pattern,and contributions to the world economy 认领 引用 被引量：1
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作者 Xi-feng Chen Gang Wang +2 位作者 Yan-xiong Mei Hai-jie Zhao Yan-yun Ma 《China Geology》 CAS CSCD 2026年第1期1-24,共24页
Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of mineral... Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of minerals,with reserves of at least 38 of over 80 widely used minerals worldwide accounting for more than30%of the global total reserves.Asia continent experienced three main tectonic evolution and mineralization stages:The Precambrian,the Paleozoic,and the Mesozoic to Cenozoic.The abundant mineral resources in this continent can be divided into seven first-order metallogenic belts(metallogenic domains),18 second-order metallogenic belts(metallogenic provinces),61 third-order metallogenic belts(metallogenic zones),and nine main minerogenetic series.Asia continent exhibits the most significant metallogenic specialization among all continents.Specifically,granite belts of Asia continent manifest pronounced metallogenic specialization of tin,rare metals,and porphyry Cu-Au-Mo deposits.Its maficultramafic rock belts and ophiolite belts display notable metallogenic specialization of lateritic nickel deposits and magmatic type chromite deposits,while its Mesozoic to Cenozoic basalt belts show remarkable metallogenic specialization of lateritic bauxite deposits.Consequently,many giant metallogenic belts were formed,including the Southeast Asian tin belt,the Qinghai-Xizang Plateau rare metal metallogenic belt,the Tethyan porphyry Cu-Au-Mo metallogenic belt,the circum-Pacific porphyry Cu-Au-Mo metallogenic belt,the Southeast Asian lateritic bauxite metallogenic belt,the Deccan Plateau lateritic bauxite metallogenic belt in India,the Southeast Asian lateritic nickel metallogenic belt,and the Tethyan magmatic type chromite metallogenic belt—all of which are significant metallogenic belts in Asia continent.Future mineral exploration in Asia should focus primarily on the Precambrian mineralization of ancient cratons,the Paleozoic mineralization of the Central Asian-Mongolian orogenic belt,and the Mesozoic to Cenozoic mineralization of the Tethyan and circum-Pacific mobile belts.Asia's mining industry not only underpins its own economic growth but also propels global economic development and industrialization,contributing significantly to the world economy.Asia boasts the highest production value of minerals,the largest annual production of minerals,and the greatest trade value of mineral products among all the continents,having emerged as the trade center of global mineral products and the center of the mining industry economy.China is identified as one of the few countries that possess the most comprehensive kinds of minerals,and its mining industry has supported and driven the economic development and industrialization of Asia and even the world.Standing as the largest mineral producer worldwide,China ranked first in the production of 28 mineral commodities in the world in 2022.Besides,China exhibits the highest annual production value of minerals and the largest trade value of mineral products among all countries.Therefore,China's demand for global mineral products influences the global supply and demand patterns of minerals and the world economic situation. 展开更多
关键词 Mineral resource endowment Minerogenetic series Metallogenic specialization Carbonate-type REE deposits Weathering-type REE deposits Hard rock-type lithium deposits Laterite nickel deposits Crystalline graphite deposits Magmatic nickel deposits Significant metallogenic belt Mining industry development pattern Mineral exploration and exploitation World economy Contribution Asia continent
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Pharmacokinetics,efficacy,and safety of a novel aripiprazole microsphere-based long-acting injectable formulation for schizophrenia:A multicenter,randomized controlled trial 认领 引用
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作者 An-Ning Li Sheng-Chun Jin +14 位作者 De-Wei Shang Jian-Xiong Guo Hua-Li Lin Ming Zhang Bo Wei Feng Wan Yun-Long Tan Li-Li Wang Jian-Chu Zhou Ping Liu Lian-Lian Fan Ju-Shui Sun Bin Chen Yimin Cui Gang Wang 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2026年第1期305-308,共4页
Schizophrenia is a severe and chronic psychiatric disorder with a lifetime prevalence of approximately 0.7%–1%worldwide[1].Aripiprazole is widely used for schizophrenia treatment,and known as a dopamine system stabil... Schizophrenia is a severe and chronic psychiatric disorder with a lifetime prevalence of approximately 0.7%–1%worldwide[1].Aripiprazole is widely used for schizophrenia treatment,and known as a dopamine system stabilizer due to its partial agonist activity as the dopamine-2(D2)and serotonin 5-hydroxytryptamine 1A(5-HT1A)receptors,as well as antagonist action at the 5-HT2A receptors[2].The investigational microsphere-based aripiprazole injection in this study is a novel long-acting formulation designed to optimize the release profile at the dose of 350 mg monthly.The objective of this study was to evaluate the pharmacokinetics,efficacy,and safety of the microsphere-based formulation,particularly the fluctuations in the peak-to-trough plasma concentration ratio. 展开更多
关键词 psychiatric disorder schizophrenia long acting injectable pharmacokinetics safety aripiprazole efficacy microsphere based
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Physics-informed neural network for material identification via distortion-robust polychromatic x-ray attenuation correction in photon-counting detectors 认领 引用
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作者 Xin Yan Jie Zhang +5 位作者 Kai He Yiheng Liu Yuetong Zhao Gang Wang Xinlong Chang Youwei Zhang 《Chinese Physics B》 SCIE EI CAS CSCD 2026年第5期396-405,共10页
Spectral distortions in photon-counting detectors(PCDs)fundamentally limit the quantitative accuracy of material identification.While machine learning is used for compensation,current data-driven methods often lack ph... Spectral distortions in photon-counting detectors(PCDs)fundamentally limit the quantitative accuracy of material identification.While machine learning is used for compensation,current data-driven methods often lack physical constraints,limiting their interpretability and reliability across varying conditions.To address this issue,we propose a physics-informed neural network(PINN)framework that explicitly embeds the Beer-Lambert law into the learning architecture.By integrating an explicit differential layer to extract high-order curvature features from distorted spectra,the model enables direct inference of the effective atomic number and areal density.This approach effectively leverages the Z-dependent non-linear profile of the photoelectric effect,even when explicit absorption edges are outside the primary detection window.Simulation results establish a high-precision benchmark for Zeffestimation in the target low-Z range(613),with an RMSE of 0.2111.Experimental validation on a CdZnTe-PCD further demonstrates that this accuracy improvement is preserved under realistic pulse pile-up and noise conditions,achieving an RMSE of 0.2457 and an R2of 0.9670.Compared with conventional physical correction methods(typically±0.5 error margin),the proposed framework provides improved precision,with 92.86%of Zeffestimation errors falling within±0.4,corresponding to an approximately 20%tighter error bound.These results confirm that the proposed framework effectively mitigates spectral distortion,providing a robust,calibration-free solution for precise material identification of low-Z materials in industrial non-destructive testing. 展开更多
关键词 physics-informed neural networks (PINNs) photon-counting detectors (PCDs) material identification x-ray imaging
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CPI-C:Cool Planet Imaging Coronagraph on Chinese Space Station Survey Telescope 认领 引用
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作者 Jiang-Pei Dou Xi Zhang +23 位作者 Gang Zhao Ming-Ming Xu Zhen Wu Gang Wang Bao-Ning Yuan Ling-Yi Kong Yi-Ming Zhu Bingli Niu Zhong-Hua Lv Yong-Jun Qi Shu Jiang Bo Chen Wei Guo Di Wang Ying-Lu Lin Li-Ping Zheng Jing Guo Ruo-Kun Li Li-Yan Xu Hui-Hai Wu Cheng Wen Shu-Wei Miao Bo-Yang Lv Wei-Miao Li 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2026年第5期275-301,共27页
Cool Planet Imaging Coronagraph(CPI-C)on Chinese Space Station Survey Telescope is proposed to direct image the cool planets around nearby solar-type stars(within 40 pc).The core scientific objective of CPI-C is to co... Cool Planet Imaging Coronagraph(CPI-C)on Chinese Space Station Survey Telescope is proposed to direct image the cool planets around nearby solar-type stars(within 40 pc).The core scientific objective of CPI-C is to conduct high-contrast directly imaging surveys of exoplanets ranging in size from Neptune-like to Jupiter-like,located at separations of 0.5–5 au from their host stars,and to perform systematic spectroscopic analysis of the detected planets through high-precision multi-band photometry.CPI-C employs a step-transmission apodization technique to suppress the diffraction noises from the telescope pupil and a precise phase correction technique to eliminate the speckle noises due to imperfections of the optical surfaces.The contrast requirement is better than 10−8 at an inner working angle of 3–4λ/D,in the visible wavelength from 600 to 900 nm.CPI-C will be the first space-based instrument capable of directly imaging the reflection light from the cool exoplanets in the visible wavelength enabling the measurement of key physical parameters such as the effective temperature,surface gravity,radius,mass,and other key parameters.The potential observation results will significantly contribute to further understand the formation and evolution mechanisms of planets,which will also lay a solid foundation for future confirmation of the Earth-twins in the next generation space flagship missions. 展开更多
关键词 space vehicles instruments-instrumentation adaptive optics-techniques high angular resolution-planets and satellites general-planets and satellites detection-planets and satellites atmospheres-planets and satellites gaseous planets-techniques image processing
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Unveiling the drivers of PM2.5 and O3 pollution rebound in Shandong,China during three periods of 2023 by an integrated machine learning method 认领 引用
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作者 Gang WANG Sai LIU +3 位作者 Kai WANG Huijuan MENG Na ZHAO Hanyu ZHANG 《Journal of Zhejiang University-SCIENCE A》 SCIE EI CAS CSCD 2026年第7期746-761,I0050-I0056,共16页
Following the relaxation of coronavirus disease 2019 restrictions and the subsequent full economic recovery,Shandong Province,China experienced a 4.3%rebound in the air quality index in 2023,with both fine particulate... Following the relaxation of coronavirus disease 2019 restrictions and the subsequent full economic recovery,Shandong Province,China experienced a 4.3%rebound in the air quality index in 2023,with both fine particulate matter(PM2.5)and ozone(O3)concentrations exhibiting noticeable upward trends.Quantifying the drivers of this rebound is essential for developing targeted air quality management strategies.To this end,the analysis focused on the early spring period(ESP,February to April)and autumn harvest period(AHP,September to October)for PM2.5 pollution and the photochemical season period(PSP,July to October)for O3 pollution.We developed an interpretable random forest-Shapley additive explanation(RF-SHAP)framework optimized with a tree-structured Parzen estimator(TPE)to assess the impacts of anthropogenic emissions and meteorological factors.The introduction of the TPE optimization technique enhanced RF model performance across these pollution periods.Anthropogenic emissions played the dominant role in PM2.5 pollution rebounds,contributing 14.1%during the ESP and 19.0%during the AHP,for example,industrial recovery(9.2%increase in energy consumption)and agricultural waste burning(70.0%increase in crop residue burning incident).In contrast,O3 pollution was more strongly influenced by meteorological conditions,which contributed a 5.8%increase during the PSP.Critical meteorological drivers included strengthened atmospheric oxidation capacity,reduced total cloud cover,and changes in boundary layer height,although precursor emissions from the transportation and petrochemical industries remained indispensable for O3 formation.This study provides an important scientific basis for precise air quality management in Shandong Province in the postpandemic period. 展开更多
关键词 Air pollution rebound Driving factors Random forest-Shapley additive explanation(RF-SHAP) Anthropogenic emissions Meteorological conditions
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Regulation of Sleep and Circadian Rhythms by S-Adenosylmethionine-Producing Probiotics 认领 引用
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作者 Peijun Tian Yuming Lan +5 位作者 Zhiying Jin Feng Hang Xuhua Mao Xing Jin Gang Wang Wei Chen 《Engineering》 SCIE EI CSCD 2026年第2期250-261,共12页
Current first-line medications for sleep disorders often overlap with antidepressants,yet their effectiveness remains suboptimal,highlighting the urgent need for novel therapeutic strategies based on new mechanisms.Ou... Current first-line medications for sleep disorders often overlap with antidepressants,yet their effectiveness remains suboptimal,highlighting the urgent need for novel therapeutic strategies based on new mechanisms.Our study initially identified a significant reduction in serum S-adenosylmethionine(SAM)levels in insomnia patients through a cross-sectional analysis,suggesting SAM as a potential biomarker and therapeutic target for sleep disorders.We then screened 60 gut strains across seven species and identified a high-SAM-producing probiotic,Lactobacillus helveticus CCFM1320,which improved cognitive and memory impairments caused by sleep deprivation in mice.Mechanistically,CCFM1320 enhances the methylation of N-acetylserotonin,a precursor of melatonin synthesis,normalizing the expression of downstream circadian rhythm genes.A subsequent four-week placebo-controlled clinical trial demonstrated that CCFM1320 significantly improved sleep quality in patients with sleep disorders,as evidenced by reduced Pittsburgh sleep quality index(PSQI)scores,lower serum cortisol levels,and decreased prevalence of pathogenic species in the gut.Probiotic treatment also elevated the abundance of SAM synthesis and metabolism-related enzyme genes in the gut microbiome,likely due to the introduction of high-SAM-producing probiotics and subsequent SAM accumulation.This study presents a promising probiotic-based strategy for managing sleep disorders,offering a potential nonpharmacological treatment alternative. 展开更多
关键词 Lactobacillus S-Adenosylmethionine Sleep Circadian rhythm Melatonin
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Mechanical behaviors and instability of rocks subjected to hydraulic progressive wetting:Acoustic emission and uniaxial compression experiments 认领 引用
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作者 Yixin Liu Jiaxin Cheng +2 位作者 Chuanhua Xu Gang Wang Jiang Xu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第1期593-610,共18页
In the field of rock engineering,the influence of water is a dynamic process that exhibits varying effects over time and across different locations.To further understand how water influences the mechanical properties ... In the field of rock engineering,the influence of water is a dynamic process that exhibits varying effects over time and across different locations.To further understand how water influences the mechanical properties and acoustic emission(AE)behavior of rocks,this study conducted uniaxial compression experiments on sandstones with varying degrees of wetting under both natural conditions and water-chemical environments.In addition,the study combined AE equipment with digital image correlation(DIC)to monitor the entire failure process.Using the sliding window algorithm,the variation in the variance of AE characteristic parameters during the process of sandstone loading to failure is analyzed from the perspective of critical slowing down.This analysis enables the effective identification of the early warning signal before failure.The experimental findings suggest that an increase in wetting height results in a gradual decrease in peak stress,accompanied by a concomitant increase in the percentage of shear cracks.The characteristic parameters,including energy,amplitude,and ringing count,all exhibit critical slowing phenomena.The waveform of AE characteristic parameters of the same sample is similar,and the mutation time of the precursor signal is roughly the same.All signals appear in the irreversible plastic deformation stage of microcrack initiation.The integration of critical slowing down theory and the b-value early warning method facilitates a more comprehensive evaluation of the stability of rock mass,thereby significantly enhancing the efficiency and safety of disaster prevention measures. 展开更多
关键词 Rock wetting and softening Uniaxial compression Acoustic emission(AE) Critical slowing Monitoring and early warning
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Nose-to-brain delivery of donepezil within a small dose improves bioavailability and efficacy for Alzheimer’s disease treatment 认领 引用
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作者 Gang Wang Xuezhe Duan +3 位作者 Defang Ouyang Jianping Zhou Huaqing Zhang Yang Ding 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS CSCD 2026年第2期194-208,共15页
Oral administration of donepezil(Don)is the first-line medication for Alzheimer’s disease(AD);however,the dysphagia of elderly patients and severe gastrointestinal side effects substantially restrict administration c... Oral administration of donepezil(Don)is the first-line medication for Alzheimer’s disease(AD);however,the dysphagia of elderly patients and severe gastrointestinal side effects substantially restrict administration compliance.Herein,we exploit a nose-tobrain pathway for Don administration to obtain smaller dosage but higher intracerebral bioavailability(BA),thereby achieving inhibition of acetylcholinesterase(AChE)activity and avoiding side effects.With respect to the intranasal administration design,a patientfriendly Don nasal spray without preservatives was developed.The administration of Don nasal spray demonstrated good nasal deposition and mucosa permeation ability comparable to that of the model drug propranolol.The mice intranasally administered Don at an equivalent oral dose(0.65 mg/kg)demonstrated rapid brain distribution(∼5 min)and long-lasting AChE inhibition effects(72 h).To obtain the optimal intranasal dose,a dosedescending study was conducted by cascading the oral dosage at a 1:3 ratio.The results demonstrated that intranasal administration of Don at 0.07 mg/kg resulted in intracerebral BA and AChE inhibition comparable to oral administration at 0.65 mg/kg,suggesting an 89%dose reduction.Compared with oral administration,anti-AD effectiveness was evaluated in AD model mice after 34-d-intranasal administration of Don,resulting in a shorter onset time,higher intracerebral drug concentration,and a longer duration of AChE inhibition(0.07 mg/kg).The nasal and systemic safety of intranasal administration of Don was confirmed in an allergic rhinitis mouse model after 4 weeks of intranasal administration.Thus,a small dose of Don exhibits improved intracerebral BA and AChE inhibition via intranasal administration,thereby offering better compliance and reducing side effects in AD treatment. 展开更多
关键词 Alzheimer’s disease Intranasal administration Small-dose donepezil Acetylcholinesterase inhibition Side effect prevention
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Tracing the evolution and progression of bladder cancer from epigenetic origins to clinical early diagnostics 认领 引用
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作者 Zilin Xu Shenjuan Li +7 位作者 Wan Xiang Hongwei Peng Mengxue Yu Kaiyu Qian Fangjin Chen Lingao Ju Yu Xiao Gang Wang 《Oncology and Translational Medicine》 CAS CSCD 2026年第3期128-131,共4页
1.Introduction Bladder cancer(BLCA),particularly the muscle-invasive(MIBC)subtype,represents one of the most challenging malignancies of the urinary tract and poses substantial difficulties in clinical management.Alth... 1.Introduction Bladder cancer(BLCA),particularly the muscle-invasive(MIBC)subtype,represents one of the most challenging malignancies of the urinary tract and poses substantial difficulties in clinical management.Although therapeutic advances such as neoadjuvant chemotherapy and immune checkpoint inhibitors have improved patient outcomes,pronounced intratumoral heterogeneity(ITH)results in considerable inter-individual variability in treatment response,contributing to treatment failure and disease recurrence.[1]Consequently,a deeper understanding of tumor evolution and precise tumor classification is critical for identifying effective therapeutic targets and diagnostic or prognostic biomarkers. 展开更多
关键词 neoadjuvant chemotherapy epigenetic origins bladder cancer intratumoral heterogeneity ith results immune checkpoint inhibitors bladder cancer blca particularly muscle invasive bladder cancer therapeutic advances
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Limosilactobacillus reuteri CCFM1132 modulates gut microbiota and alleviates hyperuricemia:a randomized,double-blind,placebo-controlled trial 认领 引用
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作者 Lei Sun Yang Cao +6 位作者 Feng Hang Dongbo Yuan Honglun Wang Jianxin Zhao Gang Wang Guohong Qiao Liyun Wang 《Food Science and Human Wellness》 SCIE CAS CSCD 2026年第1期55-66,共12页
This randomized,double-blind,placebo-controlled trial evaluated the uric acid(UA)-lowering effect of Limosilactobacillus reuteri CCFM1132 in young males with hyperuricemia.Participants received 1×1010CFU of L.... This randomized,double-blind,placebo-controlled trial evaluated the uric acid(UA)-lowering effect of Limosilactobacillus reuteri CCFM1132 in young males with hyperuricemia.Participants received 1×1010CFU of L.reuteri CCFM1132(n=34)or placebo(n=31)daily for 8 weeks.After the intervention,serum UA concentration significantly decreased,along with a reduction in xanthine oxidase(XOD)activity compared to the placebo group(P<0.01).Indicators of liver(aspartate transaminase and alanine transaminase)and renal(urea and creatinine)functions improved.Short-chain fatty acid(SCFA)concentrations significantly increased,with an upregulated abundance of SCFA producers(Fusicatenibacter,Ruminococcaceae UCG_014,and Ruminococcus 1)in the gut.Additionally,correlation analysis revealed that concentrations of SCFAs,particularly acetate and butyrate,were strongly negatively correlated with UA concentration and XOD activity.These findings suggest that L.reuteri CCFM1132 relieves hyperuricemia by enhancing the abundance of SCFA producers in the gut to promote SCFA production and by suppressing XOD activity.This study provides a valuable reference for developing new treatments for hyperuricemia. 展开更多
关键词 Hyperuricemia Limosilactobacillus reuteri Xanthine oxidase Short-chain fatty acid Gut microbiota
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Sub-inhibitory antibiotics reshape resistance dynamics in cyanobacteria-dominated waters 认领 引用
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作者 Xuefei Wu Hualong Sun +3 位作者 Gang Wang Li Liu Mengqi Zheng Guowei Chen 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第7期132-141,共10页
Cyanobacteria are competent hosts for antibiotic resistance genes,influencing the spread of bacterial resistance through their complex interactions within aquatic environments.However,the coevolution of antibiotic res... Cyanobacteria are competent hosts for antibiotic resistance genes,influencing the spread of bacterial resistance through their complex interactions within aquatic environments.However,the coevolution of antibiotic resistance between cyanobacteria and bacteria under sub-inhibitory antibiotic stresses remains unclear.To bridge this knowledge gap,we investigated the effects of Microcystis aeruginosa on modulating bacterial resistance evolution in aquatic ecosystems exposed to sub-inhibitory antibiotics.Results show that cyanobacteria reduced the abundance of antibiotic resistance bacteria(ARB) by 62 % to 93 % in antibiotic-free conditions and by up to 80 % under sub-inhibitory antibiotic concentrations.The concurrence of cyanobacteria and antibiotics significantly alter microbial community compositions,with Proteobacteria emerging as the dominant population(51 %-66 %) and Bacteroidota proliferating by 8.7-fold,alongside a significant enrichment of metabolism-related and pathogenic genes(p <0.05).Redundancy analysis revealed that ARB prevalence was positively correlated with the abundances of Proteobacteria and Bacteroidota,but negatively correlated with Cyanobacteria.Our findings suggest that cyanobacteria may reduce the spread of bacterial resistance both in antibiotic-free and sub-inhibitory antibiotic environments,by reshaping population interactions.These insights are crucial for evaluating the risk of antibiotic-driven bacterial resistance spread in cyanobacteria-rich environments and are vital for the protection and assessment of aquatic environmental quality. 展开更多
关键词 Aquatic environments Bacterial resistance Commensal cyanobacteria Population dynamics Sub-inhibitory antibiotics
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A THMC model for gas recovery from coal seams:Integrating binary gas-water adsorption and two-phase flow 认领 引用
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作者 Zhiyong Xiao Gang Wang +5 位作者 Jie Liu Huafeng Deng Yujing Jiang Feng Jiang Chengcheng Zheng Yinge Zhu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第3期2033-2058,共26页
Although extensive research has been conducted on CO2-enhanced coalbed methane(CO2-ECBM)recovery,most prior studies have focused on the impact of gas adsorption-induced swelling on coal permeability under equili... Although extensive research has been conducted on CO2-enhanced coalbed methane(CO2-ECBM)recovery,most prior studies have focused on the impact of gas adsorption-induced swelling on coal permeability under equilibrium conditions.This paper presents a comprehensive thermo-hydro-mechanical-chemical(THMC)model that integrates thermal expansion and heat conduction(T),gas diffusion in the matrix and gas-water two-phase flow in the fractures(H),matrix and fracture deformation due to poroelasticity(M),and non-equilibrium binary gas adsorption-induced matrix swelling(C)during CO2-ECBM recovery.The accuracy of the proposed model was verified through experimental data,and the model was simulated using finite element method(FEM)software.Simulation results indicate that the permeability evolution can be categorized into three stages.Ignoring the impact of water on gas adsorption properties would lead to an overestimation of the influence of adsorption-induced swelling,while disregarding non-equilibrium adsorption underestimates it.An examination of five designed cases identified critical factors influencing permeability.Parametric analysis shows that increases in the injection pressure,the injection temperature,and the initial permeability promote the competitive adsorption-induced swelling between CH4and CO2,leading to increased CH4production and CO2storage.Conversely,an increase in initial water saturation reduces available gas flow space,decreasing both CH4production and CO2storage.Higher irreducible water saturation favors early gas recovery,while lower irreducible water saturation is more advantageous for long-term recovery. 展开更多
关键词 CO2-Enhanced coalbed methane(CO2-ECBM) Binary gas adsorption Gas-water two-phase flow Non-equilibrium adsorption
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Modulation of a ramp-induced shock wave/boundary layer interaction through extended frequency range pulsed discharge 认领 引用
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作者 Hongyu WANG Hongxun LI +1 位作者 Gang WANG Tao LI 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2026年第5期216-234,共19页
Our experimental study explored the impact of pulse discharge energy deposition,across a wider frequencies ranging from 5 kHz to 20 kHz,on a Shock Wave/Boundary Layer Interaction(SWBLI)at a Mach number of 2.47.Using h... Our experimental study explored the impact of pulse discharge energy deposition,across a wider frequencies ranging from 5 kHz to 20 kHz,on a Shock Wave/Boundary Layer Interaction(SWBLI)at a Mach number of 2.47.Using high-speed schlieren imaging,Planar Laser Scattering(PLS)and Focused Laser Differential Interferometry(FLDI),we analyzed the characteristics of discharge-induced energetic eddies and their impact on SWBLI.The Spectral Proper Orthogonal Decomposition(SPOD)was employed to scrutinize the structural transformations of the flow field under the influence of pulse discharge.Our findings indicate that pulsed discharge significantly alters the flow field by propelling the separation shock upstream,with this effect intensifying as the discharge frequency increases.Additionally,the discharge diminishes the fluctuation intensity of the separation shock and the shear layer,and it reduces the low-frequency spectral energy of the separation shock.SPOD analysis revealed that at high discharge frequencies,the flow field dynamics shift from the low-frequency oscillations of the separation shock to the motion of vortices along the boundary layer,which interact with the shock waves.The control efficacy of pulsed discharge on SWBLI demonstrates remarkable consistency and intensity at frequencies of 10 kHz or higher,whereas a notable attenuation in effectiveness is observed at 5 kHz.This reveals a critical frequency threshold beyond which flow characteristics change markedly,primarily seen in the progressive weakening of the separation shock.However,further frequency increases beyond this point yield diminishing returns in SWBLI control effectiveness. 展开更多
关键词 Flow visualization Plasma flow control Shock wave/boundary layer interaction Supersonic flow Wind tunnel experiments
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Integrated Transcriptome and Lipidome to Analyze the Characteristics of Oil Accumulation in Seeds of Acer truncatum 认领 引用
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作者 Shengqun Chen Lianwen Shen +2 位作者 Shuang Qu Xia Jiang Gang Wang 《Phyton-International Journal of Experimental Botany》 SCIE 2026年第4期94-110,共17页
Acer truncatum is a significant woody oil-bearing tree species known for its ability to synthesize various unsaturated fatty acids.This study systematically analyzes the lipid metabolic pathways and the associated tra... Acer truncatum is a significant woody oil-bearing tree species known for its ability to synthesize various unsaturated fatty acids.This study systematically analyzes the lipid metabolic pathways and the associated transcript abundance changes involved in the biosynthesis and accumulation of seed oil in A.truncatum.By integrating lipidomics and transcriptomics analyses across different developmental stages of A.truncatum seeds,we thoroughly investigate the dynamic characteristics of oil metabolism.The results show that triacylglycerols(TAGs)become the dominating lipid class throughout seed development and that their amount increases greatly as the seeds mature,whereas diacylglycerols(DAGs)show a significantly decreased relative abundance.Numerous differentially expressed genes(DEGs)linked to lipid biosynthesis were identified by transcriptome analysis,including AcACCase,AcKAS,AcKCS,AcGPAT,AcDGAT,and AcOLE.The expression patterns of DGAT-and KCS-encoding genes differ noticeably between immature and mature seeds.Integrated lipidomics and transcriptomics analyses suggest stage-associated lipid metabolic changes during seed development of A.truncatum.This study also highlights candidate genes and metabolic pathways with TAG accumulation.These findings improve our understanding of seed oil metabolism in A.truncatum by linking AcDGAT-related TAG assembly and AcKCS-driven very-long-chain fatty acid elongation to the developmental regulation of the Kennedy pathway(TAG biosynthesis)and fatty acid elongation(VLCFA/NA-related),providing essential molecular insights for the genetic improvement of oil yield and fatty acid quality in this species. 展开更多
关键词 Acer truncatum triacylglycerols diacylglycerols DGAT KCS
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From feasibility to biological recovery:Reframing enhanced recovery pathways after surgery in elderly gastric cancer patients 认领 引用 被引量：2
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作者 Gang Wang Sheng-Jie Pan 《World Journal of Gastroenterology》 SCIE CAS 2026年第7期1-8,共8页
Enhanced recovery after surgery(ERAS)has reshaped perioperative care in gastrointestinal oncology,but its application in elderly gastric cancer patients requires a shift from feasibility toward a biologically grounded... Enhanced recovery after surgery(ERAS)has reshaped perioperative care in gastrointestinal oncology,but its application in elderly gastric cancer patients requires a shift from feasibility toward a biologically grounded understanding of recovery.Aging is characterized by frailty,sarcopenia,multimorbidity,chronic inflammation,and circadian vulnerability,which collectively influence postoperative resilience.Contemporary evidence shows that ERAS pathways remain feasible and safe in older adults,yet responsiveness varies widely due to physiological heterogeneity rather than chronological age alone.This Editorial reframes recovery as a multidomain process encompassing nutritional-inflammatory balance,sleep-circadian regulation,psychological resilience,and functional mobility.Targeted perioperative nutrition may support metabolic competence;structured sleep-protection strategies can stabilize endocrine-immune rhythms;psychological interventions may mitigate stress-related inflammatory activation;and digital monitoring using step-count trajectories or heart-rate variability provides early indicators of recovery deviation.Implementation challenges-including clinical workload,variable frailty,cognitive impairments,digital acceptance,and uneven access to multidisciplinary expertise-highlight the need for adaptive and pragmatic pathways.As global aging accelerates,ERAS must evolve from standardized protocols to biologically informed,patient-centered systems that align interventions with host physiology and real-time recovery signals.Such an approach may better capture recovery depth,enhance functional outcomes,and promote equitable care for elderly surgical populations. 展开更多
关键词 Enhanced recovery after surgery Gastric cancer Elderly patients Functional recovery Biological resilience Nutritional support
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Integrative acupoint stimulation within enhanced recovery after endoscopic procedures:Harnessing the neuroimmune axis for enhanced gastrointestinal recovery 认领 引用 被引量：3
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作者 Gang Wang Sheng-Jie Pan 《World Journal of Gastroenterology》 SCIE CAS 2026年第3期1-6,共6页
Enhanced recovery after surgery(ERAS)programs have transformed perioperative care,yet delayed gastrointestinal function and excessive neuroendocrine stress remain major obstacles to optimal recovery.Hong et al’s rand... Enhanced recovery after surgery(ERAS)programs have transformed perioperative care,yet delayed gastrointestinal function and excessive neuroendocrine stress remain major obstacles to optimal recovery.Hong et al’s randomized controlled trial embedded acupoint-based neuromodulation-meridian-timed acupoint application combined with transcutaneous electrical acupoint stimulation-within an ERAS framework and demonstrated accelerated gastrointestinal recovery accompanied by endocrine attenuation.This article offers a structured critical appraisal of the trial,emphasizing methodological rigor,mechanistic plausibility,and alignment with ERAS core principles of stress mitigation,functional restoration,and patient experience.The observed reductions in norepinephrine,cortisol,and aldosterone suggest modulation of the hypothalamic-pituitary-adrenal axis as a key mediator of benefit.Future research priorities include multicenter,sham-controlled validation;integration of autonomic and inflammatory biomarkers(heart rate variability,interleukin-6,tumor necrosis factor-α,C-reactive protein);and pragmatic evaluation of cost-effectiveness and acceptability.Positioning acupoint stimulation within precision-integrative perioperative care could advance ERAS from a recovery protocol to a system of host-response modulation.Integrative acupoint neuromodulation thus represents a biologically coherent,low-risk,and scalable strategy for enhancing resilience,accelerating gastrointestinal recovery,and improving surgical outcomes worldwide. 展开更多
关键词 Enhanced recovery after surgery Acupoint stimulation Gastrointestinal
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Boron‑Insertion‑Induced Lattice Engineering of Rh Nanocrystals Toward Enhanced Electrocatalytic Conversion of Nitric Oxide to Ammonia 认领 引用
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作者 Peng Han Xiangou Xu +13 位作者 Weiwei Chen Long Zheng Chen Ma Gang Wang Lei Xu Ping Gu Wenbin Wang Qiyuan He Zhiyuan Zeng Jinlan Wang Dong Su Chongyi Ling Zhengxiang Gu Ye Chen 《Nano-Micro Letters》 SCIE EI CAS CSCD 2026年第3期85-102,共18页
Electrocatalytic nitric oxide(NO)reduction reaction(NORR)is a promising and sustainable process that can simultaneously realize green ammonia(NH3)synthesis and hazardous NO removal.However,current NORR performances ar... Electrocatalytic nitric oxide(NO)reduction reaction(NORR)is a promising and sustainable process that can simultaneously realize green ammonia(NH3)synthesis and hazardous NO removal.However,current NORR performances are far from practical needs due to the lack of efficient electrocatalysts.Engineering the lattice of metal-based nanomaterials via phase control has emerged as an effective strategy to modulate their intrinsic electrocatalytic properties.Herein,we realize boron(B)-insertion-induced phase regulation of rhodium(Rh)nanocrystals to obtain amorphous Rh4B nanoparticles(NPs)and hexagonal close-packed(hcp)RhB NPs through a facile wet-chemical method.A high Faradaic efficiency(92.1±1.2%)and NH3 yield rate(629.5±11.0μmol h−1 cm−2)are achieved over hcp RhB NPs,far superior to those of most reported NORR nanocatalysts.In situ spectro-electrochemical analysis and density functional theory simulations reveal that the excellent electrocatalytic performances of hcp RhB NPs are attributed to the upshift of d-band center,enhanced NO adsorption/activation profile,and greatly reduced energy barrier of the rate-determining step.A demonstrative Zn-NO battery is assembled using hcp RhB NPs as the cathode and delivers a peak power density of 4.33 mW cm−2,realizing simultaneous NO removal,NH3 synthesis,and electricity output. 展开更多
关键词 Lattice engineering of nanomaterials Phase engineering of nanomaterials Wet-chemical synthesis Metal nanocatalysts Nitric oxide reduction reaction Electrocatalytic ammonia synthesis
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Functional adaptive genomic characteristics of gut Akkermansia in obese populations 认领 引用
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作者 Bingcong Ji Pan Huang +11 位作者 Chengcheng Zhang Chuan Zhang Gang Wang Shumao Cui Wenwei Lu Bo Yang Junjun Wu Xiaomei Lyu Fengwei Tian Jianxin Zhao Wei Chen Qixiao Zhai 《Food Science and Human Wellness》 SCIE CAS CSCD 2026年第3期1443-1453,共11页
Akkermansia,a next-generation probiotic candidate,exhibits a reduced abundance in obesity yet persists in the gut,suggesting unique adaptive mechanisms for survival in this adverse metabolic environment.To elucidate t... Akkermansia,a next-generation probiotic candidate,exhibits a reduced abundance in obesity yet persists in the gut,suggesting unique adaptive mechanisms for survival in this adverse metabolic environment.To elucidate these mechanisms,a comparative pan-genome analysis of 494 Akkermansia metagenome-assembled genomes from hosts with diverse body mass indices was conducted.It was found that the genus possesses high genetic diversity,with Akkermansia muciniphila as the dominant species(80%),though species distribution itself was not correlated with BMI.There were 15 genes significantly enriched in obese individuals.These genes may potentially be involved in pathways such as nutrient acquisition,antioxidant stress response,energy metabolism,translational fidelity,and viral defense.Co-occurrence network analysis showed that these genes are associated with pathways including the tricarboxylic acid cycle and lipoic acid metabolism.These findings suggest potential adaptive functional mechanisms of Akkermansia for survival in the obese gut environment,providing novel insights for the development of targeted probiotics addressing obesity-related conditions. 展开更多
关键词 Akkermansia Obesity Gut microbiota Pan-genome Functional adaptation Probiotics
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Mass transfer and kinetic behavior studies on cycloaddition of carbon dioxide with propylene oxide catalyzed by ionic liquid in microchannel reactor 认领 引用
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作者 Yiqian Yang Yu Chen +4 位作者 Gang Wang Hanwen Yan Lili Wang Shuguang Xiang Chunshan Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2026年第1期187-197,共11页
The synthesis of propylene carbonate(PC)from CO2 and propylene oxide(PO)is a typical gas-liquid biphasic system,where gas-liquid mass transfer efficiency significantly influences CO2 cycloaddition reactions.Here... The synthesis of propylene carbonate(PC)from CO2 and propylene oxide(PO)is a typical gas-liquid biphasic system,where gas-liquid mass transfer efficiency significantly influences CO2 cycloaddition reactions.Here,we proposed a microchannel reaction system for the CO2 cycloaddition reaction catalyzed by ionic liquid within an aqueous environment.The effect of liquid flow rate,temperature and residence time on gas-liquid flow pattern,catalytic performance and mass transfer were systematically investigated.The results revealed that the PC generation rate reached 560.11 mmol·ml−1·h−1at a 50 cm of flow distance under reaction conditions of 105℃,2.5 MPa,QG=176 ml·min−1 and QL=0.3 ml·min−1.Variations in mass transfer rate and reaction rate at different flow distances were experimentally studied.The reaction efficiency gradually decreased with increasing flow distance,which were attributed to the reduction of mass transfer caused by decreasing bubble velocity.Optimizing bubble velocity at an appropriate position enhanced reaction efficiency by improving mass transfer,achieving a 97.7%PC yield within 2.85 min.Furthermore,a kinetic model coupling intrinsic kinetics with gas-liquid mass transfer was developed for CO2 cycloaddition reaction.The kinetic model was applied to predict PC reaction rates in microchannel reactors at various temperatures and liquid flow rates,achieving an average relative error of 9.6%. 展开更多
关键词 CO2cycloaddition Ionic liquid Microchannel reactor Mass transfer Kinetic model
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Impact of CO2 cycloaddition reaction on hydrodynamics and mass transfer behavior of CO2-ionic liquid system in a capillary reactor 认领 引用
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作者 Yiqian Yang Gang Wang +2 位作者 Xiaoyan Sun Shuguang Xiang Chunshan Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2026年第3期150-160,共11页
Gas-liquid hydrodynamic characteristics under chemical reaction-enhanced mass transfer are crucial parameters for analyzing mass transfer behavior in microreactor,which can facilitate the optimization of the reaction ... Gas-liquid hydrodynamic characteristics under chemical reaction-enhanced mass transfer are crucial parameters for analyzing mass transfer behavior in microreactor,which can facilitate the optimization of the reaction conditions to achieve efficient mass transfer and improve catalytic performance.Herin,the movement and shrinkage of CO2 bubbles in the microreactor were visualized and monitored using a high-speed camera.Four typical patterns such as bubble flow,bubble-Taylor flow,Taylor flow and Taylor-annular flow were observed,and the impact of temperature on flow pattern transition lines was investigated.Furthermo re,the correlation models for predicting dimensionless initial CO2 bubble length(LB/d)and liquid-side volumetric mass transfer coefficient were developed to illustrate the effects of reaction conditions on the hydrodynamics and mass transfer behavior of CO2 bubble accompanying the chemical reaction.This work deepens the understanding of the hydrodynamics and mass transfer characteristics in a real CO2 cycloaddition reaction system and provides a theoretical basis for the design and optimization of gas-liquid microreactor. 展开更多
关键词 CO2cycloaddition Ionic liquid Microchannel reactor Mass transfer Taylor bubble hydrodynamics
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