Randomized controlled trials(RCTs)provide optimal evidence of the effectiveness and safety of a new drug,a new medical device,or a new therapeutic strategy with the necessary scientific design[1].Traditional electroni...Randomized controlled trials(RCTs)provide optimal evidence of the effectiveness and safety of a new drug,a new medical device,or a new therapeutic strategy with the necessary scientific design[1].Traditional electronic data collection(EDC)systems for clinical trials primarily focus on data entry,validation,and compliance monitoring.However,their reliance on centralized architectures introduces vulnerabilities in data security and integrity。展开更多
Storage class memory (SCM) has the potential to revolutionize the memory landscape by its non-volatile and byte-addressable properties. However, there is little published work about exploring its usage for modem vir...Storage class memory (SCM) has the potential to revolutionize the memory landscape by its non-volatile and byte-addressable properties. However, there is little published work about exploring its usage for modem virtualized cloud infrastructure. We propose SCM-vWrite, a novel architecture designed around SCM, to ease the performance interference of virtualized storage subsystem. Through a case study on a typical virtualized cloud system, we first describe why cur- rent writeback manners are not suitable for a virtualized en- vironment, then design and implement SCM-vWrite to im- prove this problem. We also use typical benchmarks and re- alistic workloads to evaluate its performance. Compared with the traditional method on a conventional architecture, the ex- perimental result shows that SCM-vWrite can coordinate the writeback flows more effectively among multiple co-located guest operating systems, achieving a better disk I/O perfor- mance without any loss of reliability.展开更多
基金supported by the National Natural Science Foundation of China(92368205 and 82301265)the Guangdong Provincial Natural Science Foundation for Progressive Young Scholars(2023A1515030170)+3 种基金the Science and Technology Planning Projects of Guangdong Province(2018B010109008)the Science and Technology Planning Project of the Guangzhou Municipal Health Commission(2024A031004)the Basic Scientific Research Projects of Sun Yat-sen University(23ykcxqt002)the China Postdoctoral Science Foundation(2023M734047).
摘要Randomized controlled trials(RCTs)provide optimal evidence of the effectiveness and safety of a new drug,a new medical device,or a new therapeutic strategy with the necessary scientific design[1].Traditional electronic data collection(EDC)systems for clinical trials primarily focus on data entry,validation,and compliance monitoring.However,their reliance on centralized architectures introduces vulnerabilities in data security and integrity。
摘要Storage class memory (SCM) has the potential to revolutionize the memory landscape by its non-volatile and byte-addressable properties. However, there is little published work about exploring its usage for modem virtualized cloud infrastructure. We propose SCM-vWrite, a novel architecture designed around SCM, to ease the performance interference of virtualized storage subsystem. Through a case study on a typical virtualized cloud system, we first describe why cur- rent writeback manners are not suitable for a virtualized en- vironment, then design and implement SCM-vWrite to im- prove this problem. We also use typical benchmarks and re- alistic workloads to evaluate its performance. Compared with the traditional method on a conventional architecture, the ex- perimental result shows that SCM-vWrite can coordinate the writeback flows more effectively among multiple co-located guest operating systems, achieving a better disk I/O perfor- mance without any loss of reliability.