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Mock Observations for the CSST Mission:Multi-Channel Imager——Instrument Simulation 认领 引用 被引量：1
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作者 Zhao-Jun Yan Huan-Yuan Shan +40 位作者 Zhen-Ya Zheng Xi-Yan Peng Zhao-Xiang Qi Chun Xu Lin Lin Xin-Rong Wen Chun-Yan Jiang Li-Xin Zheng Jing Zhong Fang-Ting Yuan Zhen-Lei Chen Wei Chen Mao-Chun Wu Zhen-Sen Fu Ke-Xin Li Lin Nie Chao Liu Nan Li Qiao Wang Zi-Huang Cao Shuai Feng Guo-Liang Li Lei Wang Cheng-Liang Wei Xiao-Bo Li Zhang Ban Xun Yang Yu-Xi Jiang De-Zi Liu Yong-He Chen Xiao-Hua Liu Fang Xu Xue Cheng Yue Su Tong-Fang Duan Chao Qi Na Li Geng Zheng Chong Ma Jing Tang Ran Li 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2026年第2期78-97,共20页
The Chinese Space Station Survey Telescope(CSST),a two-meter aperture astronomical space telescope under China's manned space program,is equipped with multiple back-end scientific instruments.As an astronomical pr... The Chinese Space Station Survey Telescope(CSST),a two-meter aperture astronomical space telescope under China's manned space program,is equipped with multiple back-end scientific instruments.As an astronomical precision measurement module of the CSST,the Multi-Channel Imager(MCI)can cover a wide wavelength range from ultraviolet to near-infrared with three-color simultaneous high-precision photometry and imaging,which meets the scientific requirements for various fields.The diverse scientific objectives of MCI require not only a robust spaceborne platform,advanced optical systems,and observing facilities but also comprehensive software support for scientific operations and research.To this end,it is essential to develop realistic observational simulation software to thoroughly evaluate the MCI data stream and provide calibration tools for future scientific investigations.The MCI instrument simulation software will serve as a foundation for the development of the MCI data processing pipeline and will facilitate improvements in both hardware and software,as well as in the observational operation strategy,in alignment with the mission's scientific goals.In conclusion,we present a comprehensive overview of the MCI instrument simulation and some corresponding performances of the MCI data processing pipeline. 展开更多
关键词 methods numerical-telescopes-techniques image processing
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Mock Observations for the CSST Mission:Main Surveys——An Overview of Framework and Simulation Suite 认领 引用 被引量：1
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作者 Cheng-Liang Wei Guo-Liang Li +26 位作者 Yue-Dong Fang Xin Zhang Yu Luo Hao Tian De-Zi Liu Xian-Ming Meng Zhang Ban Xiao-Bo Li Zun Luo Jing-Tian Xian Wei Wang Xi-Yan Peng Nan Li Ran Li Li Shao Tian-Meng Zhang Jing Tang Yang Chen Zhao-Xiang Qi Zi-Huang Cao Huan-Yuan Shan Lin Nie Zhaojun Yan Lei Wang Zizhao He Rui-Biao Luo Quan-Yu Liu 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2026年第2期1-24,共24页
The Chinese Space Station Survey Telescope(CSST)is a flagship space-based observatory.Its main survey camera is designed to conduct high spatial resolution near-ultraviolet to near-infrared imaging and low-resolution ... The Chinese Space Station Survey Telescope(CSST)is a flagship space-based observatory.Its main survey camera is designed to conduct high spatial resolution near-ultraviolet to near-infrared imaging and low-resolution spectroscopic surveys.To maximize the scientific output of CSST,we have developed a comprehensive,highfidelity simulation pipeline for reproducing both imaging and spectroscopic observations.This paper presents an overview of the simulation framework,detailing its implementation and components.Built upon the Gal Sim package and incorporating the latest CSST instrumental specifications,our pipeline generates pixel-level mock observations that closely replicate the expected instrumental and observational conditions.The simulation suite integrates realistic astrophysical object catalogs,instrumental effects,point-spread function modeling,and observational noises to produce accurate synthetic data.We describe the key processing stages of the simulation,from constructing the input object catalogs to modeling the telescope optics and detector responses.Furthermore,we introduce the most recent release of simulated datasets,which provide a crucial testbed for data processing pipeline developments,calibration strategies,and scientific analyses,ensuring that CSST will meet its stringent requirements.Our pipeline serves as a vital tool for optimizing CSST main survey strategies and ensuring robust cosmological measurements. 展开更多
关键词 methods numerical-surveys-virtual observatory tools
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The updated requirements and functional roles of dietary protein and amino acids in ducks:a comprehensive review 认领 引用
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作者 Yongbao Wu Yong Jiang +2 位作者 Jing Tang Shuisheng Hou Zhiguo Wen 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2026年第4期1771-1790,共20页
Waterfowl,primarily ducks,constitute a major commercial poultry species globally,their production efficiency is heavily influenced by dietary protein and amino acid intake.Although the National Research Council(NRC,Nu... Waterfowl,primarily ducks,constitute a major commercial poultry species globally,their production efficiency is heavily influenced by dietary protein and amino acid intake.Although the National Research Council(NRC,Nutrient requirements of poultry,1994)established fundamental recommendations for protein and amino acid requirements in ducks,tremendous improvements and changes(growth speed,rearing system,and dietary strategy)have been made in duck industry over the past decades.Consequently,these standards no longer adequately reflect the nutritional needs of modern duck production systems.This review presents updated estimates of dietary crude protein and key amino acid requirements,including methionine,lysine,threonine,tryptophan,and arginine,etc.,which are essential for formulating precision diets to maximize growth performance,carcass yield in meat ducks,as well as reproductive performance in laying ducks and breeders.Furthermore,the functional roles of these amino acids as critical regulators of physiological processes are systematically examined,including lipid metabolism(methionine and threonine),intestinal barrier integrity(threonine),regulation of feed intake via nitric oxide(arginine),and the modulation of behavior and stress responses(tryptophan).The implementation of low-protein dietary strategies(crude protein levels as low as 15%for growing meat ducks,and 14.5%for laying ducks)is also discussed for maintaining performance while improving nitrogen utilization efficiency.The recent publication of updated Chinese national feeding standards for meat-type(GB/T 45103-2024)and laying ducks(GB/T 41189-2021)incorporates these modern research advances,representing a significant milestone and providing a modern framework to guide the global duck industries.In summary,this review highlights the urgent need to move beyond outdated nutritional standards and adopt modern,evidence-based amino acid requirements tailored to modern duck production.The integration of low-protein diet strategies along with a refined understanding of amino acid functions is crucial for optimizing duck production,enhancing nutrient efficiency,and reducing environmental impacts.Future research should focus on establishing the precise requirements for other essential amino acids and certain non-essential amino acids,and further elucidating how amino acids molecularly modulate gene expression,signaling pathways,and gut microbiota to develop innovative and sustainable nutritional strategies for ducks. 展开更多
关键词 Amino acid requirement Duck nutrition Functional role Growth performance Low-protein diet Precision feeding
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Cadonilimab Plus Lenvatinib Combined with Stereotactic Body Radiotherapy for Conversion Therapy in Unresectable or Potentially Resectable Hepatocellular Carcinoma:A Study Protocol 认领 引用
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作者 Jia-jia Fu Jin-feng Zhang +6 位作者 Dong-en Liu Zhen-yu Lin Hong-li Liu Jian-li Hu Tao Zhang Jing Tang Jun Xue 《Current Medical Science》 SCIE CAS CSCD 2026年第2期563-572,共10页
Background Conversion therapy offers a critical opportunity to convert potentially resectable hepatocellular carcinoma(HCC)to surgically resectable status;yet,its optimal protocol and efficacy remain unstandardized an... Background Conversion therapy offers a critical opportunity to convert potentially resectable hepatocellular carcinoma(HCC)to surgically resectable status;yet,its optimal protocol and efficacy remain unstandardized and controversial.As a first-line systemic treatment for advanced HCC,immunotherapy combined with targeted therapy has demonstrated robust antitumor activity.Accumulating evidence suggests that radiotherapy can render some unresectable HCC patients amenable to surgical resections.Given these advancements,this study aims to investigate the efficacy and safety of cadonilimab(a dual immune checkpoint inhibitor targeting PD-1 and CTLA-4)plus lenvatinib(a multi-targeted tyrosine kinase inhibitor)combined with stereotactic body radiotherapy(SBRT),with the goal of achieving conversion therapy for potentially resectable HCC and prolonging survival for unresectable HCC.Methods This is a single-arm,single-center exploratory cohort study designed to enroll 27 HCC patients who meet the following eligibility criteria:surgically unresectable China Liver Cancer Staging(CNLC)stage Ia,Ib,or IIIa,or surgically resectable CNLC stage IIb or IIa.Eligible patients will undergo comprehensive tumor evaluation at three key time points:pre-conversion therapy(cadonilimab+lenvatinib+SBRT),after the second treatment cycle,and preoperatively.Postoperatively,patients will be followed up every six weeks for long-term efficacy and safety monitoring.The primary endpoint is the objective response rate(ORR),assessed using the Response Evaluation Criteria in Solid Tumors(RECIST)v1.1 and modified RECIST(mRECIST)criteria;in case of inconsistent results between the two criteria,mRECIST will serve as the primary reference.Secondary endpoints include surgical resection rate,major pathological response(MPR)rate,duration of response(DOR),disease control rate(DCR),progression-free survival(PFS),time to disease progression(TTP),overall survival(OS),and the incidence and severity of treatment-related adverse events(AEs).AEs will be graded in accordance with the National Cancer Institute Common Terminology Criteria for Adverse Events(NCI CTCAE)version 5.0 and coded using the Medical Dictionary for Regulatory Activities(MedDRA),respectively.Discussion This study is designed to evaluate the efficacy and safety of cadonilimab combined with lenvatinib and SBRT for conversion therapy in patients with potentially resectable HCC.By integrating dual immune checkpoint inhibition,anti-angiogenic targeted therapy,and high-precision local radiotherapy,this regimen leverages synergistic antitumor effects to address the unmet clinical need for optimized conversion strategies in HCC.This exploratory trial will provide critical clinical evidence for this novel triple-combination conversion therapy,enriching treatment options for patients with potentially resectable or technically unresectable HCC.The findings are expected to lay a solid foundation for future large-scale,multi-center randomized controlled trials to further validate the clinical value of this regimen.Trial Registration:Chinese Clinical Trials Registration No.ChiCTR2300068781. 展开更多
关键词 Hepatocellular carcinoma(HCC) Conversion therapy Stereotactic body radiotherapy(SBRT) Cadonilimab Immunotherapy Targeted therapy
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Mock Observations for the CSST Mission:Main Surveys——The Slitless Spectroscopy Simulation 认领 引用
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作者 Xin Zhang Yue-Dong Fang +14 位作者 Cheng-Liang Wei Guo-Liang Li Feng-Shan Liu Hang-Xin Ji Hao Tian Nan Li Xian-Min Meng Jian-Jun Chen Xia Wang Rui Wang Chao Liu Zhong-Wen Hu Ran Li Peng Wei Jing Tang 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2026年第2期40-48,共9页
The Chinese Space Station Survey Telescope(CSST),slated to become China's largest space-based optical telescope in the coming decade,is designed to conduct wide-field sky surveys with high spatial resolution.Among... The Chinese Space Station Survey Telescope(CSST),slated to become China's largest space-based optical telescope in the coming decade,is designed to conduct wide-field sky surveys with high spatial resolution.Among its key observational modes,slitless spectral observation allows simultaneous imaging and spectral data acquisition over a wide field of view,offering significant advantages for astrophysical studies.Currently,the CSST is in the development phase and lacks real observational data.As a result,the development of its data processing pipeline and scientific pre-research must rely on the mock data generated through simulations.This work focuses on developing a simulation framework for the CSST slitless spectral imaging system,analyzing its spectral dispersing properties and structural design.Additionally,the detection performance of the slitless spectral system is assessed for various astrophysical targets.Simulation results demonstrate that nearly all 1st order spectra are accompanied by corresponding 0th order images,facilitating accurate source identification.Furthermore,the GI spectral band exhibits superior detection efficiency compared to the GV and GU bands,establishing it as the primary observational band for stellar and galactic studies.This work successfully develops a simulation framework for the CSST slitless spectroscopic equipment. 展开更多
关键词 methods numerical-methods data analysis-techniques imaging spectroscopy-space vehicles instruments
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Mock Observations for the CSST Mission:Integral Field Spectrograph-Instrument Simulation 认领 引用
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作者 Zhao-Jun Yan Jun Yin +26 位作者 Lei Hao Shi-Yin Shen Wei Chen Shuai Feng Yi-Fei Xiong Chun Xu Xin-Rong Wen Lin Lin Chao Liu Lin Long Zhen-Lei Chen Mao-Chun Wu Xiao-Bo Li Zhang Ban Xun Yang Yu-Xi Jiang Guo-Liang Li Ke-Xin Li Jian-Jun Chen Nan Li Cheng-Liang Wei Lei Wang Bai-Chuan Ren Jun Wei Jing Tang Yang Yang Ran Li 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2026年第2期108-123,共16页
The Chinese Space Station Survey Telescope(CSST)is a next-generation Stage-IV facility renowned for its wide field of view,high image quality,and multi-band observational capabilities.Among the five instruments onboar... The Chinese Space Station Survey Telescope(CSST)is a next-generation Stage-IV facility renowned for its wide field of view,high image quality,and multi-band observational capabilities.Among the five instruments onboard the CSST,the Integral Field Spectrograph(IFS)offers the unique ability to simultaneously capture spatial and spectral information across a field of view of no less than 6″×6″.Key advantages of the IFS include a high spatial resolution of 0.2 and a broad spectral coverage from 350 to 1000 nm,making it an ideal instrument for studying physical processes in the vicinity of supermassive black holes within galaxies.To more accurately assess the technical and scientific performance of the CSST-IFS,it is essential to develop a simulation tool that incorporates realistic effects from all optical components.Such a simulation will form an integral part of the CSST-IFS data and pipeline system,enabling the development of the data reduction pipeline well ahead of actual observations.This paper presents an endto-end simulation workflow for the CSST-IFS,incorporating a wide range of instrumental effects that may influence its spectral and imaging performance.The simulation accounts for optical diffraction effects introduced by all components,such as image slicers and slit array,as well as sub-pixel effects from gratings.It also includes various detector noises,frame-shifting effects,and charge-transfer inefficiency.Real observational conditions-such as target Doppler shift,cosmic rays,and other in-orbit operational effects-are also considered.We describe the technical implementation of the simulation and present results that quantitatively characterize key instrument parameters. 展开更多
关键词 instrumentation spectrographs-methods numerical-techniques imaging spectroscopy
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A Single-Device Environment-Adaptive Mixed Reality Framework for Real-Time Industrial Fault Diagnosis 认领 引用
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作者 Xueyi Li Bo Kang +3 位作者 Jing Tang Qi Li Tianyang Wang Minwei Zhang 《Journal of Dynamics, Monitoring and Diagnostics》 2026年第1期64-73,共10页
In industrial environments,monitoring and fault diagnosis of mechanical equipment face challenges such as spatial localization drift and delays in real-time data rendering,especially in complex settings with low illum... In industrial environments,monitoring and fault diagnosis of mechanical equipment face challenges such as spatial localization drift and delays in real-time data rendering,especially in complex settings with low illumination,weak textures,and strong interference.Traditional methods struggle to effectively integrate monitoring data with physical entities,increasing cognitive load and reducing diagnostic accuracy.To address these issues,we propose the Single-Device Mixed Reality(SEMR)framework,a novel solution that enhances industrial equipment monitoring and fault diagnosis.The framework integrates three key mechanisms:an environment-aware model that adjusts the confidence of Simultaneous Localization and Mapping(SLAM)to ensure precise spatial registration,a Kalman filter-based motion prediction to reduce rendering delays,and a faulttolerant gaze interaction system for hands-free operation.Experimental results demonstrate that SEMR reduces the spatial registration error by 52.1%,from 14.2 cm to 6.8 cm,and decreases latency during dynamic inspections by 26.7%,improving diagnostic accuracy and real-time performance.The proposed method provides a costeffective and reliable solution for enhancing industrial fault diagnosis and equipment monitoring,particularly in challenging environments. 展开更多
关键词 adaptive SLAM fault diagnosis industrial inspection predictive interaction real-time equipment status monitoring single-device mixed reality
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Directional Reconstruction of Spent Lithium Cobalt Oxide by Microwave Plasma:Efficient Oxygen Evolution Catalyst from Closed-Loop Recovered Resources 认领 引用
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作者 Chao Chen Qixuan Zhu +8 位作者 Minghui Shan Lei Cheng Weiwei Wang Zhiqiang Lu Yi Wang Hengda Sun Yusuke Yamauchi Jing Tang Guiyin Xu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2026年第9期894-909,共16页
The key challenge of water electrolysis is the high energy barrier of the oxygen intermediate of the oxygen evolution reaction(OER)and the unclear catalytic active sites.The recycling of valuable metals from spent bat... The key challenge of water electrolysis is the high energy barrier of the oxygen intermediate of the oxygen evolution reaction(OER)and the unclear catalytic active sites.The recycling of valuable metals from spent batteries and their reconstruction into high-performance electrolytic water catalysts offers significant economic and environmental benefits.In this work,we report a Co3O4/NiFe-layered double hydroxide heterostructure electrocatalyst by reconstruction of spent LiCoO2cathode material through microwave plasma treatment and then compositing with NiFe-layered double hydroxides through a simple hydrothermal method.This catalyst achieves a low overpotential of 235 mV at 10 mA cm-2for OER and exhibits prolonged stability at high current densities when integrated into an alkaline electrolyzer,which surpasses commercial IrO2.In situ spectral analysis and density functional theory demonstrate that the presence of heterostructures between Co3O4 and NiFe-LDH optimizes the charge transport path and reduces the interface resistance.Specifically,the charge redistribution optimizes the adsorption energy of oxygenated intermediates on the Ni and Fe sites,thereby optimizing the reaction pathway and significantly improving the overall OER catalytic efficiency.This work provides a green and scalable way to convert spent metal sources into high-value electrocatalysts,while addressing critical challenges in energy storage and sustainable hydrogen production. 展开更多
关键词 Battery recycling Microwave plasma treatment Heterostructure Electrolyzed water
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Oxygen Vacancies Modulation of Ammonium Tungsten Bronze by NH4+-Assisted Heat Treatment for Highly Sensitive Detection of NO2 认领 引用
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作者 Qiu-Yue Zheng Xiao-Li Cheng +8 位作者 Jing Tang Ting-Ting Wang Xian-Fa Zhang Li-Hua Huo Chao-Bo Huang Zoltán Major Yong-Sheng Zhang Peng-Jin Ye Ying-Ming Xu 《Rare Metals》 SCIE EI CAS CSCD 2026年第1期334-343,共10页
Introducing oxygen vacancies has emerged as an essential strategy to affect the sensing properties of nanomaterials.However,existing methods for manipulating oxygen require high cost,complex operation,and harsh condit... Introducing oxygen vacancies has emerged as an essential strategy to affect the sensing properties of nanomaterials.However,existing methods for manipulating oxygen require high cost,complex operation,and harsh conditions.Herein,a simple NH4+-assisted heat treatment approach was designed to regulate the concentration of oxygen vacancies of ammonium tungsten bronze((NH4)0.25WO3,named as NWO).The resultant NWO-300 sensor exhibited an extremely high response of 118 to 1 ppm NO2 at 40℃.It achieved a detection limit as low as 10 ppb.Such outstanding sensing properties of NWO-300 were ascribed to the modulated electronic structure and increased active sites caused by oxygen vacancies.The formation of a large number of oxygen vacancies in NWO-300 is due to the H and N atoms in NH3 can extract O atoms on the surface of materials,which was confirmed by X-ray photoelectron spectroscopy(XPS) and thermogravimetric-mass spectrometry(TG-MS) techniques.Moreover,the excellent NO2 detection ability of the NWO-300 sensor enables the detection of air quality under different floors,and its development can be utilized in the field of environmental monitoring applications. 展开更多
关键词 ammonium tungsten bronze NO2sensing oxygen vacancies modulation practical application
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Mock Observations for the CSST Mission:CPI-C——Targets for High Contrast Imaging 认领 引用
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作者 Yi-Ming Zhu Gang Zhao +6 位作者 Jiang-Pei Dou Zhong-Hua Lv Yi-Li Chen Bo Ma Zhao-Jun Yan Jing Tang Ran Li 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2026年第2期148-160,共13页
We introduce CPISM,a simulation program developed for the Cool Planet Imaging Coronagraph(CPI-C)on the Chinese Space Station Survey Telescope.CPISM supports high-contrast exoplanet imaging by simulating observational ... We introduce CPISM,a simulation program developed for the Cool Planet Imaging Coronagraph(CPI-C)on the Chinese Space Station Survey Telescope.CPISM supports high-contrast exoplanet imaging by simulating observational conditions and instrumental effects to optimize target selection and observation strategies.The modular design includes target modeling,imaging simulation,observational effects,detector response,and data product generation modules,enabling flexible and realistic synthetic observations.Validation through simulations of a bright star shows strong agreement with theoretical expectations,confirming the program's accuracy.CPISM's modular design allows flexibility,accommodating different stellar and planetary models,and can simulate instrumental noise,cosmic rays,and other observational effects.This tool aids in data processing,signalto-noise ratio analysis,and high-contrast photometry,contributing to future exoplanet discovery and characterization efforts.The program's outputs will enhance observation planning and scientific return for the CPI-C mission,providing critical insights into exoplanetary systems. 展开更多
关键词 planets and satellites atmospheres-planets and satellites detection-instrumentation adaptive optics
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Mock Observations for the CSST Mission:HSTDM——Synthetic Data Generation 认领 引用
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作者 Siyuan Tan Wenyin Duan +9 位作者 Yilong Zhang Yiping Ao Yan Gong Zhenhui Lin Xuan Zhang Yong Shi Jing Tang Jing Li Ruiqing Mao Sheng-Cai Shi 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2026年第2期161-176,共16页
The High Sensitivity Terahertz Detection Module(HSTDM),a key component of the backend modules on board the Chinese Space Station Survey Telescope(CSST),will offer great opportunities for the discovery of terahertz ast... The High Sensitivity Terahertz Detection Module(HSTDM),a key component of the backend modules on board the Chinese Space Station Survey Telescope(CSST),will offer great opportunities for the discovery of terahertz astronomy,with implications that extend well beyond China to the global astronomical community.It is imperative that the raw data collected by HSTDM undergo meticulous calibration and processing through the HSTDM data processing pipeline(HSTDM pipeline for short)to ensure the accuracy and effectiveness of the final science data to be archived for further research.This process necessitates that the HSTDM pipeline address instrumental artifacts and effects as well as the coordination of data flow of the scheduled observing sequences under all observing modes of HSTDM within the CSST automated processing environment.As the understanding of CSST HSTDM data processing develops during the pipeline development stage,it becomes essential to assess the accuracy,robustness and performance of the HSTDM pipeline under all observing modes of HSTDM so that components of the HSTDM pipeline be rationally added,removed,amended or extended within the modular framework.In this paper,we develop practical simulation methods to facilitate this need.The contribution of synthetic data generation of HSTDM observation includes two parts:(1)HSTDM instrumental effect simulation based on both real testing profiles and simulated models;(2)Observing data flow generation based on HSTDM observing mode scenario.The simulation methods have been implemented and shown to be practical in testing the HSTDM pipeline during the development stage. 展开更多
关键词 telescopes-instrumentation detectors-methods data analysis
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Exceptional roles by protozoa on enhancing degraded soil quality 认领 引用
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作者 Jing Tang Yuting Zhao +8 位作者 Kexin Yu Mei Han Wenyuan Wang Pan Zhou Jing Luo Xuming Pan Duu-Jong Lee Li Wang Jianye Li 《Ecological Frontiers》 CSCD 2026年第2期498-506,共9页
Degraded arable land globally results in soil aggregate breakdown and biodiversity loss.Protozoa,key consumers in soil microfood webs,have underexplored roles in improving soil quality.This study investigates for the ... Degraded arable land globally results in soil aggregate breakdown and biodiversity loss.Protozoa,key consumers in soil microfood webs,have underexplored roles in improving soil quality.This study investigates for the first time the impact of three protozoa on soil aggregate formation,nutrient changes,and biome dynamics in eroded arable soil.Results show that Colpoda inflata,Blepharisma americanum,and Tetrahymenapyriformis significantly enhance ag-gregate formation.Colpoda inflata notably increases large macroaggregates(LMA)carbon content by 93.3%and re-duces acidification by 8.5%.Blepharisma americanum significantly raises nitrate nitrogen and ammonium nitrogen levels by 1529.5%and 215.1%,respectively,compared to the control.Tetrahymena pyriformis contributes to an 18%increase in total nitrogen.Colpoda inflata,Blepharisma americanum,and Tetrahymenapyriformis increase bacterial abundance by 8.4%,2.6%,and 28.5%,respectively,while reducing fungal abundance by 44.5%,90.8%,and 74.2%.The Chao1,Shannon,and Simpson indices of bacterial and fungal diversity did not change significantly(p>0.05).These findings underscore the crucial roles of protozoa in eroded soil ecosystems,offering significant insights into their potential to improve soil health and quality. 展开更多
关键词 Soil degradation Soil aggregate Microbial community Soil nutrients Soil organic carbon
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Research progress on the environmental risk assessment and remediation technologies of heavy metal pollution in agricultural soil 认领 引用 被引量：27
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作者 Xurui Mai Jing Tang +6 位作者 Juexuan Tang Xinyue Zhu Zhenhao Yang Xi Liu Xiaojie Zhuang Guang Feng Lin Tang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2025年第3期1-20,共20页
Controlling heavy metal pollution in agricultural soil has been a significant challenge.These heavy metals seriously threaten the surrounding ecological environment and human health.The effective assessment and remedi... Controlling heavy metal pollution in agricultural soil has been a significant challenge.These heavy metals seriously threaten the surrounding ecological environment and human health.The effective assessment and remediation of heavy metals in agricultural soils are crucial.These two aspects support each other,forming a close and complete decisionmaking chain.Therefore,this review systematically summarizes the distribution characteristics of soil heavy metal pollution,the correlation between soil and crop heavy metal contents,the presence pattern and migration and transformation mode of heavy metals in the soil-crop system.The advantages and disadvantages of the risk evaluation tools and models of heavy metal pollution in farmland are further outlined,which provides important guidance for an in-depth understanding of the characteristics of heavymetal pollution in farmland soils and the assessment of the environmental risk.Soil remediation strategies involve multiple physical,chemical,biological and even combined technologies,and this paper compares the potential and effect of the above current remediation technologies in heavy metal polluted farmland soils.Finally,the main problems and possible research directions of future heavy metal risk assessment and remediation technologies in agricultural soils are prospected.This review provides new ideas for effective assessment and selection of remediation technologies based on the characterization of soil heavy metals. 展开更多
关键词 Source Migration transformation Risk assessment Remediation Heavy metals Agricultural soils
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Ultra-short cyclic peptide CyRL-QN15acts as a TLR4 antagonist to expedite oral ulcer healing 认领 引用 被引量：4
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作者 Ze-Qiong Ru Yu-Tong Wu +18 位作者 Chong-Yu Yang Ya-Ting Yang Ya-Jie Li Min Liu Ying Peng Yu-Liu Yang Jun-Yuan Wang Qiu-Ye Jia Yuan-Sheng Li Zhe Fu Mei-Feng Yang Jing Tang Yan Fan Cheng-Xing Liu Wen-Rou Su Nai-Xin Liu Li He Ying Wang Xin-Wang Yang 《Zoological Research》 SCIE CAS CSCD 2025年第5期1187-1202,共16页
Oral ulcers(OUs)are among the most common lesions of the oral mucosa,typically associated with pain and burning sensations,and remain clinically challenging due to the scarcity of effective treatment options.Cy_(RL-QN... Oral ulcers(OUs)are among the most common lesions of the oral mucosa,typically associated with pain and burning sensations,and remain clinically challenging due to the scarcity of effective treatment options.CyRL-QN15,a novel ultra-short cyclic heptapeptide recently shown to promote skin repair,diabetic wound healing,and follicle neogenesis,was evaluated for its therapeutic potential in mucosal repair.Using a rat OU model and a primary oral epithelial cell inflammation model,CyRL-QN15significantly accelerated wound closure through coordinated modulation of immune-epithelial crosstalk,including suppression of inflammatory cytokine release from macrophages and neutrophils,reduction of pro-inflammatory factor secretion by oral epithelial cells,and enhancement of their proliferation and migration.Mechanistic studies employing alanine scanning mutagenesis and microscale thermophoresis revealed that CyRL-QN15directly interacted with Toll-like receptor 4(TLR4)via a methionine-dependent binding interface(Kd=2.64μmol/L),thereby inhibiting downstream MyD88/NF-κB signaling.As the first ultra-short cyclic heptapeptide identified to antagonize TLR4,CyRL-QN15represents a mechanistically distinct immunomodulatory scaffold that restores mucosal homeostasis and offers a promising therapeutic candidate for TLR4-based OU intervention. 展开更多
关键词 Ultra-short peptide Oral ulcer TLR4 antagonist Inflammation MyD88/NF-κB signaling pathway Macrophage polarization
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Analytical solution for estimating the minimum required strength of sill mat by considering failure due to rock wall closure 认领 引用 被引量：2
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作者 Chuan Fan Li Li +3 位作者 Guangsheng Liu Xiaocong Yang Lijie Guo Jing Tang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2025年第2期996-1007,共12页
Underhand cut-and-fill mining has been widely used in underground mining operations,especially when the rock mass or orebody is of poor quality or prone to rockburst due to high stress.In such cases,mining workers sho... Underhand cut-and-fill mining has been widely used in underground mining operations,especially when the rock mass or orebody is of poor quality or prone to rockburst due to high stress.In such cases,mining workers should carry out all production activities under the cemented backfill roof or sill mat instead of a highly fractured and unstable rock roof or a strong rock roof with a high potential of rockburst.Therefore,the stability and required strength of the sill mat are critical issues for mining engineers.In 1991,Mitchell considered that sill mat could fail by caving,sliding,rotation,and flexure.Mitchell also proposed an analytical solution to determine the minimum required strength of the sill mat for each type of failure based on two stiff or immobile rock walls.However,recent publications using numerical modeling and field measurements indicate that the compressive stresses in the sill mat induced by rock wall closure due to a stope excavation beneath the sill mat can be significant.It is thus highly necessary to investigate the required strength of the sill mat by considering rock wall closure.In this study,the crushing failure of sill mat due to rock wall closure generated by underground excavation and a new failure mode called"crushing and caving”is revealed by numerical modeling.An analytical solution corresponding to each failure mode is then developed to estimate the minimum required cohesion(cmin)of the sill mat.A criterion is also proposed to determine if the sill mat fails by crushing or crushing-and-caving failure.The proposed analytical solution does not involve any correction coefficients.The validity of the proposed analytical solution is demonstrated by numerical modeling.The proposed analytical solution can thus be employed to predict the cmin of sill mat subjected to wall closure generated by underlying stope excavation. 展开更多
关键词 Underhand cut-and-fill mining Cemented backfill Wall closure Crushing Required strength Analytical solution
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Analytical solution for determining wall closure associated with stope excavation underneath sill mat constructed by cemented backfill 认领 引用 被引量：2
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作者 Chuan Fan Li Li +3 位作者 Xiaocong Yang Guangsheng Liu Lijie Guo Jing Tang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2025年第2期983-995,共13页
In the underhand cut-and-fill mining method,a sill mat(i.e.an artificial horizontal pillar)constructed by cemented backfill is essential to prevent mine workers from being directly exposed under problematic rock roofs... In the underhand cut-and-fill mining method,a sill mat(i.e.an artificial horizontal pillar)constructed by cemented backfill is essential to prevent mine workers from being directly exposed under problematic rock roofs.A critical issue is to determine the minimum required strength of the sill mat to ensure a safe and cost-effective design.Until now,Mitchell’s analytical solution is the only available option,considering two stiff and immobile rock walls.Unavoidable rock wall closure associated with stope excavation below the sill mat was neglected.This,along with other undefined parameters,explains why Mitchell’s solution is rarely used in sill mat design.A new analytical solution for determining the minimum required strength of the sill mat accounting for wall closure is necessary.In this study,a closed-form analytical solution for estimating rock wall closure generated by stope excavation below a sill mat is developed by using Salamon’s and Flamant’s models.The proposed analytical solution does not contain any coefficients of correction or calibration.Despite several assumptions(or somewhat of oversimplifications)necessary to render a simple analytical solution possible,good agreements are obtained between the rock wall closures predicted by applying the proposed analytical solution and those obtained numerically with FLAC3D for many cases with arbitrarily chosen geometrical and material parameters.The proposed analytical solution is therefore validated and can be used to evaluate the rock wall closure generated by stope excavation below a sill mat. 展开更多
关键词 Underhand cut-and-fill mining Backfill Wall closure Analytical solution FLAC3D Flamant model
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Equivalent loading method for the thin-walled floors of armored vehicles with bottom explosion impacts 认领 引用 被引量：1
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作者 Weiwei Qin Jiahao He +6 位作者 Shaoyan Zhang Tuzao Yao Jing Tang Xianhui Wang Xiaowang Sun Tao Wang Qiang Zhou 《Defence Technology（防务技术）》 SCIE EI CAS CSCD 2025年第10期184-206,共23页
The high cost and low efficiency of full-scale vehicle experiments and numerical simulations limit the efficient development of armored vehicle occupant protection systems.The floor-occupant-seat local simulation mode... The high cost and low efficiency of full-scale vehicle experiments and numerical simulations limit the efficient development of armored vehicle occupant protection systems.The floor-occupant-seat local simulation model provides an alternative solution for quickly evaluating the performance of occupant protection systems.However,the error and rationality of the loading of the thin-walled floor in the local model cannot be ignored.This study proposed an equivalent loading method for the local model,which includes two parts:the dimensionality reduction method for acceleration matrix and the joint optimization framework for equivalent node coordinates.In the dimensionality reduction method,the dimension of the acceleration matrix was reduced based on the improved kernel principal component analysis(KPCA),and a dynamic variable bandwidth was introduced to address the limitation of failing to effectively measure the similarity between acceleration data in conventional KPCA.In addition,a least squares problem with forced displacement constraints was constructed to solve the correction matrix,thereby achieving the scale restoration process of the principal component acceleration matrix.The joint optimization framework for coordinates consists of the error assessment of response time histories(EARTH)and Bayesian optimization.In this framework,the local loading error of the equivalent acceleration matrix is taken as the Bayesian optimization objective,which is quantified and scored by EARTH.The expected improvement acquisition function was used to select the new set of the equivalent acceleration node coordinates for the self-updating optimization of the observation dataset and Gaussian process surrogate model.We reduced the dimension of the acceleration matrix from 2256 to 7,while retaining 91%of the information features.The comprehensive error score of occupant's lower limb response in the local model increased from 58.5%to 80.4%.The proposed equivalent loading method provides a solution for the rapid and reliable development of occupant protection systems. 展开更多
关键词 Armored vehicles Local model Equivalent loading Dimensionality reduction Bayes optimization
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Combination of anlotinib and albumin-bound paclitaxel in 2ndline and above treatment of advanced gastric cancer:A retrospective study 认领 引用 被引量：1
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作者 Wen-Ming Liu Yi-Rui Liu +2 位作者 Yi Peng Jing Tang Xiao-Bing Li 《World Journal of Clinical Oncology》 2025年第4期119-129,共11页
BACKGROUND Chemotherapy combined with anti-angiogenic therapy has become an important strategy for the treatment of advanced gastric cancer(AGC);however,the regimen needs optimization.AIM To evaluate the efficacy of a... BACKGROUND Chemotherapy combined with anti-angiogenic therapy has become an important strategy for the treatment of advanced gastric cancer(AGC);however,the regimen needs optimization.AIM To evaluate the efficacy of albumin-bound paclitaxel(nab-ptx)combined with the small molecule vascular endothelial growth factor inhibitor anlotinib in secondline and beyond treatment of AGC.METHODS We collected data from AGC patients at our hospital who experienced disease progression after first-line chemotherapy and received anlotinib combined with nab-ptx.The primary endpoints included overall survival(OS)and progressionfree survival(PFS),while the secondary endpoints were objective response rate(ORR),disease control rate(DCR),and adverse events(AEs).RESULTS Preliminary results indicated that anlotinib combined with nab-ptx can provide significant efficacy in second-line or above treatment for AGC(median PFS=6.0 months,median OS=12.0 months),with an ORR of 42%and a DCR of 78%.Further analysis revealed that patients who experienced hypertension,proteinuria,and hand-foot syndrome during treatment had better efficacy compared to those who did not experience these AEs.Mechanistic studies suggest that this regimen likely exerts synergistic anti-tumor effects by activating the immune response through the reduction of regulatory T-cell proportions.Common adverse reactions included bone marrow suppression,peripheral neuropathy,hypertension,proteinuria,and hand-foot syndrome,which were manageable and resolved with appropriate interventions,indicating the promising application of this regimen in second-line or above treatment for AGC.CONCLUSION The combination of anlotinib and nab-ptx shows promising efficacy with fewer toxicities in AGC treatment.The regimen holds promise as a second-line treatment of AGC;however,its specific clinical value requires further research. 展开更多
关键词 Advanced gastric cancer Drug combination Albumin-bound paclitaxel Anlotinib Cohort study
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Epidemiology and risk of pulmonary complications following hepatobiliary surgical procedures:A retrospective study 认领 引用
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作者 Hui-Jie Meng Zhong-Hao Chen +4 位作者 Guang-Meng Nie Zhao-Shuai Ji Yu-Jie Wang Yong-Fang Hu Jing Tang 《World Journal of Gastrointestinal Surgery》 SCIE 2025年第9期251-261,共11页
BACKGROUND Postoperative pulmonary complications(PPCs)are the most common complications following major upper abdominal surgeries,particularly hepatobiliary procedures,and significantly compromise surgical outcomes an... BACKGROUND Postoperative pulmonary complications(PPCs)are the most common complications following major upper abdominal surgeries,particularly hepatobiliary procedures,and significantly compromise surgical outcomes and patients’quality of life.Although the adoption of laparoscopy has lowered their incidence,PPCs remain a frequent and serious concern after hepatobiliary surgery.Existing research on risk factors specific to hepatobiliary surgeries is limited,particularly regarding the epidemiology and risk factors of PPCs in liver and gallbladder surgeries in China.Therefore,this study aimed to investigate the risk factors for PPCs in a large hepatobiliary center.AIM To identify the incidence and risk factors for PPCs following hepatobiliary surgery based on perioperative variables.METHODS Retrospective data were collected from patients who underwent liver,gallbladder,or pancreatic surgery at a hepatobiliary center in China between May 2023 and December 2023.We retrospectively reviewed comprehensive medical records to extract demographic and hospital admission information for determining PPC incidence.Statistically significant variables were initially screened through univariate analysis,followed by binary logistic regression modeling to identify independent predictors of PPCs.Hospitalization expenditures and duration of stay were further contrasted across the study cohorts.RESULTS This study included 1941 patients who underwent liver,gallbladder,or pancreatic surgery,of whom 78 developed PPCs,resulting in an incidence rate of 4.02%.Logistic regression analysis revealed two independent predictors of PPCs in hepatobiliary surgery patients:Age≥75 year(odds ratio=8.350,95%CI:3.521-19.798,P<0.001)and prolonged anesthesia(odds ratio=1.052,95%CI:1.015-1.091,P=0.006).Patients with PPCs had significantly elevated healthcare resource utilization,including higher total hospitalization costs,increased medication expenses,longer hospital stays,and extended postoperative admissions(all P<0.001).CONCLUSION Age≥75 years and prolonged anesthesia emerged as independent predictors of PPCs following hepatobiliary surgery.These complications were correlated with protracted hospitalization and increased healthcare costs. 展开更多
关键词 Postoperative pulmonary complications Hepatobiliary surgical procedures Risk factors Retrospective study Epidemiology
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Relationship between corneal stiffness and glaucoma severity:clinical insights from Corvis ST technology 认领 引用 被引量：1
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作者 Meng-Zhen Xie Yong-Kang Zhou +4 位作者 Ying-Ping Deng Xiao-Lan Zhang Zhi-Yong Huang Li Tang Jing Tang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2025年第11期2089-2098,共10页
AIM:To explore the mechanical indices used for differential diagnosis and to investigate the relationship between ocular biomechanics and glaucoma severity within each group.METHODS:This cross-sectional study included... AIM:To explore the mechanical indices used for differential diagnosis and to investigate the relationship between ocular biomechanics and glaucoma severity within each group.METHODS:This cross-sectional study included 185 eyes from 185 subjects:62 normal controls,91 hightension glaucoma(HTG),and 32 normal-tension glaucoma(NTG)patients.All participants underwent a comprehensive ophthalmic examination that involved ocular biomechanical measurements.Glaucoma severity was assessed using visual field index(VFI),mean deviation(MD),pattern standard deviation(PSD)and retinal nerve fiber layer(RNFL)thickness.Multivariable models were used to compare fifteen biomechanical parameters among the three groups adjusting for age,gender,intraocular pressure(IOP),central corneal thickness(CCT),and axial length(AL).The generalized linear model was utilized for multifactor comparison.RESULTS:Significant differences in first applanation time(AT1),highest concavity time(HC time),stress strain index(SSI),and HC deflection were found among the three groups(P<0.05).AT1 was significantly higher in the HTG group compared to controls(P<0.05),and SSI was higher in HTG than NTG(P<0.05).HC deflection in the HTG group was significantly smaller than in NTG(P<0.05).Furthermore,AT1 levels were observed to be significantly higher in primary open angle glaucoma(POAG)patients compared to controls(P<0.05).Receiver operating charactristic(ROC)analysis showed HC deflection had an area under the curve(AUC)of 0.802 between HTG and NTG.A negatively significant correlation was observed between SSI and VFI in POAG patients.CONCLUSION:Biomechanical analysis reveals that corneas in POAG patients are stiffer than normal controls,with increased corneal stiffness correlating with more severe glaucomatous damage.Interestingly,stiffer corneas in NTG patients appeares protective.In addition,HC deflection may be useful for differentiating HTG and NTG. 展开更多
关键词 corneal biomechanics glaucoma primary open angle glaucoma normal-tension glaucoma
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