Beer is a prominent fermented food product and is regarded as the one of most widely consumed beverage globally.There is a dearth of studies examining the impact of different types of beer with intricate components as...Beer is a prominent fermented food product and is regarded as the one of most widely consumed beverage globally.There is a dearth of studies examining the impact of different types of beer with intricate components as a comprehensive intervention on human health and immune status.This study used a 14-day continuous drinking intervention consisting of 5 beers,namely white beer,India pale ale(IPA),Pilsner,non-alcoholic beer,and premium lager beer.Surprisingly,our findings indicate that consuming white beer has little impact on the gut microbiota and physiological condition of mice,whereas consuming other types of beer leads to an increase in Lactobacillus and a decrease in Lachnospiraceae.In addition,we devised an extended feeding experiment to investigate the comparative safety and health benefits of consuming white beer.The research showed that when mice drank excessive quantities of white beer over 42 days,the intestines of the mice had more Prevotellaceae and the Firmicutes to Bacteroidetes ratio(F/B ratio)had a decline from 1.29 to 0.38.The levels of acetic acid,propionic acid,and isobutyric acid increased from 1.0,0.27,and 0.015 mg/g to 1.28,0.38,and 0.037 mg/g,respectively(P<0.05).There were no significant changes observed in the levels of most measured cytokines in the colon tissue of mice that consumed beer,however,there was an increase in the concentration of the inflammatory factor tumor nesrosis factor-α(TNF-α)from 135.86 pg/mL in the control group to 189.78 pg/mL in the white beer group(P<0.01).These results give us real-world proof that we can use to study how different beers affect the host’s health and satisfaction in future research.展开更多
Although the slippage effect has been extensively studied,most of the previous studies focused on the impact of the slippage effect on apparent permeability within a low pore pressure range,resulting in the inability ...Although the slippage effect has been extensively studied,most of the previous studies focused on the impact of the slippage effect on apparent permeability within a low pore pressure range,resulting in the inability of matching the evolution of permeability in the remaining pressure range.In this paper,a new apparent permeability model that reveals the evolution of permeability under the combined action of effective stress and slippage in the full pore pressure range was proposed.In this model,both intrinsic permeability and slippage coefficient are stress dependent.Three experimental tests with pore pressure lower than 2 MPa and a test with pore pressure at about 10 MPa using cores from the same origin under constant confining stress and constant effective stress are conducted.By comparing experimental data and another apparent permeability model,we proved the fidelity of our newly developed model.Furthermore,the contribution factor of the slippage effect Rslip is used to determine the low pore pressure limit with significant slippage effect.Our results show that both narrow initial pore size and high effective stress increase the critical pore pressure.Finally,the evolutions of the slippage coefficient and the intrinsic permeability under different boundary conditions were analyzed.展开更多
Beer is a fermented beverage prepared from water,malted barley,hops,and yeast that has been around for centuries.Alcoholic beverages alter the composition of the gut microbiota,which in turn causes oxidative stress br...Beer is a fermented beverage prepared from water,malted barley,hops,and yeast that has been around for centuries.Alcoholic beverages alter the composition of the gut microbiota,which in turn causes oxidative stress brought on by alcohol,increases intestinal permeability to luminal bacterial products.However,beer has been shown to contain several intriguing non-alcoholic chemicals.Recent research demonstrates that moderate beer drinking could have positive impacts on human health.Beer’s non-alcoholic ingredients have a significant impact on gut microbiota,and this type of diet is known to modulate gut microbiota,which has a variety of effects on the body,including effects on intestinal permeability,mucosal immune function,intestinal motility,antioxidant activity,and anti-inflammatory activity.Although the negative consequences of excessive alcohol intake are widely known,it is still debatable whether or not some non-alcoholic components,such as polyphenols and carbohydrates,have any positive benefits.In this review,we explain the primary benefits of moderate beer consumption on the gut microbiota,which are mostly attributable to non-alcoholic components such polyphenols.Despite any potential advantages of moderating consumption of alcoholic beverages,the lowest alcohol intake is the most secure.展开更多
Survey on fertility of tea garden soil in Meizhou region indicates that tea garden soil has strong acidity; organic matter content remains at medium level; there is a severe lack of available content of nitrogen(N),ph...Survey on fertility of tea garden soil in Meizhou region indicates that tea garden soil has strong acidity; organic matter content remains at medium level; there is a severe lack of available content of nitrogen(N),phosphorus(P) and potassium(K); available calcium(Ca) and magnesium(Mg) content is also insufficient; available sulfur(S) is abundant. In the management of tea cultivation,it is recommended to supplement organic fertilizer,balance the application of NPK fertilizer,and adequately alleviate shortage of Ca and Mg element,to guarantee high and stable yield of tea.展开更多
Metal-organic frameworks(MOFs),which are self-assembled porous coordination materials,have garnered considerable attention in the fields of optoelectronics,photovoltaic,photochemistry,and photocatalysis due to their d...Metal-organic frameworks(MOFs),which are self-assembled porous coordination materials,have garnered considerable attention in the fields of optoelectronics,photovoltaic,photochemistry,and photocatalysis due to their diverse structures and excellent tunability.However,the performance of MOF-based optoelectronic applications currently falls short of the industry benchmark.To enhance the performance of MOF materials,it is imperative to undertake comprehensive investigations aimed at gaining a deeper understanding of photophysics and sequentially optimizing properties related to photocarrier transport,recombination,interaction,and transfer.By utilizing femtosecond laser pulses to excite MOFs,time-resolved optical spectroscopy offers a means to observe and characterize these ultrafast microscopic processes.This approach adds the time coordinate as a novel dimension for comprehending the interaction between light and MOFs.Accordingly,this review provides a comprehensive overview of the recent advancements in the photophysics of MOFs and additionally outlines potential avenues for exploring the time domain in the investigation of MOFs.展开更多
Excitonics,an alternative to romising for processing information since semiconductor electronics is rapidly approaching the end of Moore’s law.Currently,the development of excitonic devices,where exciton flow is cont...Excitonics,an alternative to romising for processing information since semiconductor electronics is rapidly approaching the end of Moore’s law.Currently,the development of excitonic devices,where exciton flow is controlled,is mainly focused on electric-field modulation or exciton polaritons in high-Q cavities.Here,we show an alloptical strategy to manipulate the exciton flow in a binary colloidal quantum well complex through mediation of the Förster resonance energy transfer(FRET)by stimulated emission.In the spontaneous emission regime,FRET naturally occurs between a donor and an acceptor.In contrast,upon stronger excitation,the ultrafast consumption of excitons by stimulated emission effectively engineers the excitonic flow from the donors to the acceptors.Specifically,the acceptors’stimulated emission significantly accelerates the exciton flow,while the donors’stimulated emission almost stops this process.On this basis,a FRET-coupled rate equation model is derived to understand the controllable exciton flow using the density of the excited donors and the unexcited acceptors.The results will provide an effective alloptical route for realizing excitonic devices under room temperature operation.展开更多
Optical logic gates call for materials with giant optical nonlinearity to break the current performance bottleneck.Metal–organic frameworks(MOFs)provide an intriguing route to achieve superior optical nonlinearity be...Optical logic gates call for materials with giant optical nonlinearity to break the current performance bottleneck.Metal–organic frameworks(MOFs)provide an intriguing route to achieve superior optical nonlinearity benefitting from structural diversity and design flexibility.However,the potential of MOFs for optoelectronics has been largely overlooked and their applications in optical logic have not been exploited.Here,through temporally manipulating the nonlinear optical absorption process in porphyrin-based MOFs,we have successfully developed AND and XOR logic gates with an ultrafast speed approaching 1 THz and an on–off ratio above 90%.On this basis,all-optical information encryption is further demonstrated using transmittance as primary codes,which shows vast prospects in avoiding the disclosure of security information.To the best of our knowledge,this is the first exploration of MOFs for applications in ultrafast optical logic devices and information encryption.展开更多
基金financially supported by the National Key R&D Program of China(2022YFA1304103)Agricultural Scientific and Technological Innovation Project of Shandong Academy of Agricultural Sciences(CXGC2024A04)SKLMT Frontiers&Challenges Project.
摘要Beer is a prominent fermented food product and is regarded as the one of most widely consumed beverage globally.There is a dearth of studies examining the impact of different types of beer with intricate components as a comprehensive intervention on human health and immune status.This study used a 14-day continuous drinking intervention consisting of 5 beers,namely white beer,India pale ale(IPA),Pilsner,non-alcoholic beer,and premium lager beer.Surprisingly,our findings indicate that consuming white beer has little impact on the gut microbiota and physiological condition of mice,whereas consuming other types of beer leads to an increase in Lactobacillus and a decrease in Lachnospiraceae.In addition,we devised an extended feeding experiment to investigate the comparative safety and health benefits of consuming white beer.The research showed that when mice drank excessive quantities of white beer over 42 days,the intestines of the mice had more Prevotellaceae and the Firmicutes to Bacteroidetes ratio(F/B ratio)had a decline from 1.29 to 0.38.The levels of acetic acid,propionic acid,and isobutyric acid increased from 1.0,0.27,and 0.015 mg/g to 1.28,0.38,and 0.037 mg/g,respectively(P<0.05).There were no significant changes observed in the levels of most measured cytokines in the colon tissue of mice that consumed beer,however,there was an increase in the concentration of the inflammatory factor tumor nesrosis factor-α(TNF-α)from 135.86 pg/mL in the control group to 189.78 pg/mL in the white beer group(P<0.01).These results give us real-world proof that we can use to study how different beers affect the host’s health and satisfaction in future research.
基金supported by the National Natural Science Foundation of China(No.52079077)the Natural Science Foundation of Shandong Province(No.ZR2021QE069)China Postdoctoral Science Foundation(No.2019M662402).
摘要Although the slippage effect has been extensively studied,most of the previous studies focused on the impact of the slippage effect on apparent permeability within a low pore pressure range,resulting in the inability of matching the evolution of permeability in the remaining pressure range.In this paper,a new apparent permeability model that reveals the evolution of permeability under the combined action of effective stress and slippage in the full pore pressure range was proposed.In this model,both intrinsic permeability and slippage coefficient are stress dependent.Three experimental tests with pore pressure lower than 2 MPa and a test with pore pressure at about 10 MPa using cores from the same origin under constant confining stress and constant effective stress are conducted.By comparing experimental data and another apparent permeability model,we proved the fidelity of our newly developed model.Furthermore,the contribution factor of the slippage effect Rslip is used to determine the low pore pressure limit with significant slippage effect.Our results show that both narrow initial pore size and high effective stress increase the critical pore pressure.Finally,the evolutions of the slippage coefficient and the intrinsic permeability under different boundary conditions were analyzed.
基金supported by the Agricultural Scientific and Technological Innovation Project of Shandong Academy of Agricultural Sciences(CXGC2024A04).
摘要Beer is a fermented beverage prepared from water,malted barley,hops,and yeast that has been around for centuries.Alcoholic beverages alter the composition of the gut microbiota,which in turn causes oxidative stress brought on by alcohol,increases intestinal permeability to luminal bacterial products.However,beer has been shown to contain several intriguing non-alcoholic chemicals.Recent research demonstrates that moderate beer drinking could have positive impacts on human health.Beer’s non-alcoholic ingredients have a significant impact on gut microbiota,and this type of diet is known to modulate gut microbiota,which has a variety of effects on the body,including effects on intestinal permeability,mucosal immune function,intestinal motility,antioxidant activity,and anti-inflammatory activity.Although the negative consequences of excessive alcohol intake are widely known,it is still debatable whether or not some non-alcoholic components,such as polyphenols and carbohydrates,have any positive benefits.In this review,we explain the primary benefits of moderate beer consumption on the gut microbiota,which are mostly attributable to non-alcoholic components such polyphenols.Despite any potential advantages of moderating consumption of alcoholic beverages,the lowest alcohol intake is the most secure.
基金Supported by Agricultural Mechanization Research Program of Guangdong Province "Application and Demonstration of Multi-functional and Intelligent Water and Fertilizer Application Facilities"
摘要Survey on fertility of tea garden soil in Meizhou region indicates that tea garden soil has strong acidity; organic matter content remains at medium level; there is a severe lack of available content of nitrogen(N),phosphorus(P) and potassium(K); available calcium(Ca) and magnesium(Mg) content is also insufficient; available sulfur(S) is abundant. In the management of tea cultivation,it is recommended to supplement organic fertilizer,balance the application of NPK fertilizer,and adequately alleviate shortage of Ca and Mg element,to guarantee high and stable yield of tea.
基金Project supported by the Science Challenge Project(Grant No.TZ2018001)the National Natural Science Foundation of China(Grant Nos.11872058 and 21802036)the Project of State Key Laboratory of Environment-friendly Energy Materials,and Southwest University of Science and Technology(Grant No.21fksy07)。
摘要Metal-organic frameworks(MOFs),which are self-assembled porous coordination materials,have garnered considerable attention in the fields of optoelectronics,photovoltaic,photochemistry,and photocatalysis due to their diverse structures and excellent tunability.However,the performance of MOF-based optoelectronic applications currently falls short of the industry benchmark.To enhance the performance of MOF materials,it is imperative to undertake comprehensive investigations aimed at gaining a deeper understanding of photophysics and sequentially optimizing properties related to photocarrier transport,recombination,interaction,and transfer.By utilizing femtosecond laser pulses to excite MOFs,time-resolved optical spectroscopy offers a means to observe and characterize these ultrafast microscopic processes.This approach adds the time coordinate as a novel dimension for comprehending the interaction between light and MOFs.Accordingly,this review provides a comprehensive overview of the recent advancements in the photophysics of MOFs and additionally outlines potential avenues for exploring the time domain in the investigation of MOFs.
基金financial support through the AcRF Tier1 grant(MOE2019-T1-002-087)the Singapore National Research Foundation for financial support under the Program of NRF-NRFI-2016-08financial support from the TUBA.
摘要Excitonics,an alternative to romising for processing information since semiconductor electronics is rapidly approaching the end of Moore’s law.Currently,the development of excitonic devices,where exciton flow is controlled,is mainly focused on electric-field modulation or exciton polaritons in high-Q cavities.Here,we show an alloptical strategy to manipulate the exciton flow in a binary colloidal quantum well complex through mediation of the Förster resonance energy transfer(FRET)by stimulated emission.In the spontaneous emission regime,FRET naturally occurs between a donor and an acceptor.In contrast,upon stronger excitation,the ultrafast consumption of excitons by stimulated emission effectively engineers the excitonic flow from the donors to the acceptors.Specifically,the acceptors’stimulated emission significantly accelerates the exciton flow,while the donors’stimulated emission almost stops this process.On this basis,a FRET-coupled rate equation model is derived to understand the controllable exciton flow using the density of the excited donors and the unexcited acceptors.The results will provide an effective alloptical route for realizing excitonic devices under room temperature operation.
基金supported by Science Challenge Project(no.TZ2018001)National Natural Science Foundation of China(nos.11872058 and 21802036)Project of State Key Laboratory of Environment-friendly Energy Materials,and Southwest University of Science and Technology(21fksy07).
摘要Optical logic gates call for materials with giant optical nonlinearity to break the current performance bottleneck.Metal–organic frameworks(MOFs)provide an intriguing route to achieve superior optical nonlinearity benefitting from structural diversity and design flexibility.However,the potential of MOFs for optoelectronics has been largely overlooked and their applications in optical logic have not been exploited.Here,through temporally manipulating the nonlinear optical absorption process in porphyrin-based MOFs,we have successfully developed AND and XOR logic gates with an ultrafast speed approaching 1 THz and an on–off ratio above 90%.On this basis,all-optical information encryption is further demonstrated using transmittance as primary codes,which shows vast prospects in avoiding the disclosure of security information.To the best of our knowledge,this is the first exploration of MOFs for applications in ultrafast optical logic devices and information encryption.