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Techno-Economic and Environmental Impact Assessment of Membrane Bioreactors for Wastewater Treatment:A Review 认领 引用 被引量：2
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作者 Tingwei Gao Yana Jin Kang Xiao 《Engineering》 SCIE EI CSCD 2026年第4期297-311,共15页
Despite the advantages of high effluent quality and small footprint,membrane bioreactor(MBR)technology faces challenges in sustainable development due to energy consumption and membrane fouling.Weighing the advantages... Despite the advantages of high effluent quality and small footprint,membrane bioreactor(MBR)technology faces challenges in sustainable development due to energy consumption and membrane fouling.Weighing the advantages and disadvantages of MBRs requires a comprehensive assessment from techno-economic-environmental perspectives.In this paper,we reviewed the related research on MBRs from three aspects:economic cost analysis,environmental impact assessment,and comprehensive techno-economic-environmental assessment.The aim of this paper is to understand the sustainable development performance of MBRs,and to review the current status of the application of multiple techno-economic-environmental assessment methods in the field of wastewater treatment.The currently available results of the economic cost analysis of MBRs showed that the operating cost and energy consumption of MBRs are higher than those of other wastewater treatment processes if MBRs’potential benefit of smaller footprint is not taken into account.The results of the environmental impact assessment showed that MBRs have a positive environmental impact due to high quality effluent,although global warming potential limits the sustainability of MBRs to some extent.Combined techno-economic-environmental assessment showed that MBRs are economically feasible and technically efficient,while their sustainability is controversial.Given the rapid development of MBR technology,these results may evolve as new advancements are made.In addition,there is room for improvement in the existing literature regarding the reliability and comparability of results,as well as the applicability of the methods,particularly in defining the accounting scope,clarifying model assumptions,and considering discounting. 展开更多
关键词 Membrane bioreactor Economic analysis Environmental impact Carbon emission Sustainability analysis
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Metabolite-derived fluorescence signals track decay of biochemical oxygen demand throughout dissolved organic matter biodegradation 认领 引用
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作者 Hehe Wang Yinghui Mo +6 位作者 Kang Xiao Yichen Tian Yizhe Lai Xin Zhao Jianqing Du Jihua Tan Xia Huang 《ENGINEERING Environment》 SCIE EI CAS CSCD 2026年第6期1-14,共14页
Monitoring biochemical oxygen demand(BOD)decay offers critical insights into the aerobic biodegradation of dissolved organic matter(DOM).Focusing on the accumulated metabolites generated during DOM biodegradation,this... Monitoring biochemical oxygen demand(BOD)decay offers critical insights into the aerobic biodegradation of dissolved organic matter(DOM).Focusing on the accumulated metabolites generated during DOM biodegradation,this study introduces novel fluorescence parameters that facilitate the rapid monitoring of BOD decay throughout the entire DOM degradation process until BOD is depleted.BOD decay during degradation of four synthetic DOM samples was first investigated(initial BOD0.93;p0.8;p<0.001).The findings present a promising approach for rapid tracking and early warning of BOD decay during DOM degradation,potentially contributing to water quality management. 展开更多
关键词 Biochemical oxygen demand Dissolved organic matter Fluorescence spectroscopy Kinetic modeling Metabolites
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基于城市更新的社区景观设计研究进展 认领 引用
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作者 李成 宁佳慧 +1 位作者 康霄 吴亚伟 《山东建筑大学学报》 2026年第2期118-125,共8页
城市更新是城市发展建设的阶段性系统工程,社区是城市更新的基本单元,社区景观设计是城市更新的重要构成内容,通过景观更新可重塑空间格局,创造更加优质的生活场景。文章以系统论为基础,探讨城市社区景观更新的设计策略与方法,从构建舒... 城市更新是城市发展建设的阶段性系统工程,社区是城市更新的基本单元,社区景观设计是城市更新的重要构成内容,通过景观更新可重塑空间格局,创造更加优质的生活场景。文章以系统论为基础,探讨城市社区景观更新的设计策略与方法,从构建舒适、美观、绿色、宜居社区景观空间的目标出发,提出社区景观更新的三元融合路径;通过构建多维度评价体系,研判生态环境短板与人文景观需求,提出了点-线-面层级递进的景观更新方法,涵盖微空间活化、线性街道景观叙事化、面状空间功能复合化等策略,未来景观特征将趋向动态化、叙事化和全民化发展,从而为推进社区景观更新发展提供方法借鉴。 展开更多
关键词 城市更新 社区景观 更新设计 生态人文
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滑动摩擦处理强化AgCu10合金的微纳摩擦性能 认领 引用
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作者 曹怡璇 涂有旺 +2 位作者 朱修崇 康潇 张雷 《中南大学学报（自然科学版）》 EI CSCD 北大核心 2026年第2期562-574,共13页
Ag-Cu合金是航天等领域中重要的载流摩擦材料。为了提升该材料的减摩抗磨能力,本文通过滑动摩擦处理(SFT)对其进行了表面强化处理,探究了不同载荷对滑动摩擦处理表面强化层的组织结构、力学性能与微观摩擦行为的影响。研究结果表明:滑... Ag-Cu合金是航天等领域中重要的载流摩擦材料。为了提升该材料的减摩抗磨能力,本文通过滑动摩擦处理(SFT)对其进行了表面强化处理,探究了不同载荷对滑动摩擦处理表面强化层的组织结构、力学性能与微观摩擦行为的影响。研究结果表明:滑动摩擦处理能够显著提升铸轧态与粉末冶金(PM)态AgCu10合金的表面硬度、耐磨性及摩擦稳定性,但两者达到最佳摩擦性能的载荷值差异显著,其中,PM态合金在60 N载荷下具有最低的摩擦因数,较未处理样品降低了34.6%,对应磨损率降低了47.7%,上述强化效应源于滑动摩擦处理诱导表层形成了Ag(Cu)过饱和固溶体;PM态合金因其初始组织中含细小弥散分布的富Cu相,更有利于Cu原子向Ag基体的固溶,从而形成更厚、更稳定的表面强化层,有效改善了Ag-Cu合金的力学性能以及微纳摩擦性能。 展开更多
关键词 银铜合金 表面强化 微纳摩擦 过饱和固溶体
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黄河上游典型深水水库沉积物-水界面氮迁移特征及驱动机制 认领 引用
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作者 徐升 任雷 +4 位作者 张肖雄 刘英杰 康宵 刘嘉龙 吴巍 《环境科学学报》 CAS CSCD 北大核心 2026年第5期276-287,共12页
沉积物-水界面氮迁移与转化是水生态系统演变的重要过程.在深水水库中,该界面环境呈现“低温、高压、变氧”的典型特征.因此,阐明氮在其中的生物地球化学循环及其对环境的响应机制,是评估与预测深水水库界面营养盐动态的重要科学基础.... 沉积物-水界面氮迁移与转化是水生态系统演变的重要过程.在深水水库中,该界面环境呈现“低温、高压、变氧”的典型特征.因此,阐明氮在其中的生物地球化学循环及其对环境的响应机制,是评估与预测深水水库界面营养盐动态的重要科学基础.本研究通过现场检测、实验模拟及随机森林模型等手段,系统量化了静水压力作用下深水水库沉积物-水界面氮迁移通量,揭示了“低温-高压-变氧”特殊环境对界面氮循环的驱动机制.结果表明,龙羊峡水库沉积物-水界面各形态氮浓度具有时空异质性,这是水文条件、微生物活动及人类活动(如旅游业与网箱养殖)共同调控的结果.环境因子对沉积物-水界面氮迁移通量有不同程度的影响,静水压力是深水水库独特的背景性物理因子,其定义了深水水库的物理和微生物背景场,温度调控了所有过程的速率,溶解氧决定了氮迁移的主导形态与路径,pH则通过微化学环境调节着吸附-解吸与生物转化的平衡.本研究旨在为深水水库沉积物-水界面氮迁移通量及驱动机制提供新的见解. 展开更多
关键词 深水水库 沉积物-水界面 静水压力 实验模拟 交换通量
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石吊兰总黄酮通过TLR4/NF-κB/NLRP3信号通路抑制细胞焦亡进而减轻DSS诱导的小鼠溃疡性结肠炎 认领 引用
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作者 王震 夏景 +4 位作者 李均昊 董倩男 康晓 詹康 张棽 《中国病理生理杂志》 CAS CSCD 北大核心 2026年第7期1390-1400,共11页
目的:探究石吊兰总黄酮(total flavonoids of Lysionotus pauciflorus Maxim,LPMTF)对葡聚糖硫酸钠(dextran sulfatesodium,DSS)诱导的小鼠溃疡性结肠炎的减轻作用。方法:将48只SPF级C57BL/6小鼠随机分为6组,分别为正常组、模型组、LPMT... 目的:探究石吊兰总黄酮(total flavonoids of Lysionotus pauciflorus Maxim,LPMTF)对葡聚糖硫酸钠(dextran sulfatesodium,DSS)诱导的小鼠溃疡性结肠炎的减轻作用。方法:将48只SPF级C57BL/6小鼠随机分为6组,分别为正常组、模型组、LPMTF低剂量(82.2 mg·kg-1·d-1)组、中剂量(164.4 mg·kg-1·d-1)组、高剂量(328.8 mg·kg-1·d-1)组,及阳药(美沙拉嗪300 mg·kg-1·d-1)组,每组8只。其中,正常组小鼠每天自由饮用纯净水,连续10 d,其余各组自由饮用3%DSS溶液,连续7 d,其中各给药组在开始造模同时每天灌胃给药,连续10 d,正常组与模型组则每天给予等量蒸馏水,观察小鼠体重及疾病活动指数(disease activity index,DAI)变化,苏木素-伊红(hematoxylin-eosin,HE)法观察小鼠结肠组织病理损伤情况,阿利新蓝-过碘酸-雪夫(Alcian blue-periodic acid-Schiff,AB-PAS)染色观察杯状细胞数量变化,ELISA检测小鼠血清中肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)、白细胞介素1β(interleukin-1β,IL-1β)和IL-6表达水平,免疫荧光法检测p-NF-κB p65的核转位情况,Western blot检测Toll样受体4(toll-like receptor 4,TLR4)、核因子κB p65亚基(nuclear factor kappa-B p65 subunit,NF-κB p65)、NOD样受体家族含pyrin结构域蛋白3(NLR family pyrin domain containing 3,NLRP3)、含CARD结构域的凋亡相关斑点样蛋白(apoptosis-associated speck-like protein containing a CARD,ASC)、剪切型caspase-1(cleaved caspase-1)、消皮素D N端片段(gasdermin D N-terminal fragment,GSDMD-N)等相关蛋白的表达水平。结果:与模型组相比,LPMTF各剂量组能够缓解小鼠体重减轻,降低小鼠疾病活动指数(disease activity index,DAI)评分(P<0.05或P<0.01),使小鼠结肠长度恢复(P<0.05),能够减轻小鼠结肠病理损伤和炎症浸润(P<0.05)。ELISA结果表明,经LPMTF治疗后,小鼠血清中TNF-α、IL-1β、IL-6表达水平显著降低(P<0.05或P<0.01)。免疫荧光结果显示,相较于模型组,给药组NF-κB p65的核转位显著减弱(P<0.05),同时TLR4、p-NF-κB p65/NF-κB p65、NLRP3、ASC、cleaved caspase-1和GSDMD-N等蛋白的表达均下调(P<0.05或P<0.01)。结论:LPMTF能够通过TLR4/NF-κB/NLRP3信号通路抑制细胞焦亡进而减轻DSS诱导的小鼠溃疡性结肠炎。 展开更多
关键词 石吊兰总黄酮 溃疡性结肠炎 炎症 细胞焦亡
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Large-Scale Membrane Bioreactors for Industrial Wastewater Treatment in China:Technical and Economic Features,Driving Forces,and Perspectives 认领 引用 被引量：18
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作者 Jiao Zhang Kang Xiao +3 位作者 Ziwei Liu Tingwei Gao Shuai Liang Xia Huang 《Engineering》 SCIE EI CAS CSCD 2021年第6期868-880,共13页
Membrane bioreactors(MBRs)have been and will continue playing an important role in industrial wastewater treatment and reuse in China.The sustainable development of MBR technology in its mature-application stage requi... Membrane bioreactors(MBRs)have been and will continue playing an important role in industrial wastewater treatment and reuse in China.The sustainable development of MBR technology in its mature-application stage requires reciprocal interactions between engineering and research participants.Thus,in this study,a total of 182 large-scale MBR projects treating industrial wastewater(with individual treatment capacities5000 m3d1)commissioned and under construction from 2003 to 2019 were analyzed comprehensively.Fast growth of the cumulative treatment capacity was observed,with extension to diverse industries,and the super large-scale was enhanced recently.The treatment processes,pollutant removal efficiencies,and actual operational parameters were summarized regarding the particularity of industrial wastewater compared to municipal wastewater.Economic features including the total investment costs of the projects,their total footprint,and their operational energy consumption were analyzed as well.A vigorous MBR market has formed in China with the fast development of membrane elements and engineering suppliers,continuously increasing official oriented projects,and responsive and innovative business modes.MBR technology has been mostly applied in specific economic zones and water-deficient areas,but its widespread use all over China is foreseeable considering the vast future market for industrial wastewater treatment and recycling.The policy–economy and market–technology driving forces revealed that MBR is consistent with the national development demand.According to the survey and analysis,prospective development in both engineering and research aspects of MBR is proposed to maintain its competitive edge. 展开更多
关键词 Full-scale application Treatment capacity Parameter Footprint Geographic demand Policy
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母亲为适龄女生接种人乳头瘤病毒疫苗意愿影响因素分析 认领 引用 被引量：5
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作者 邱晓菲 康晓 +5 位作者 庄文文 高日月 张德磊 邵燕燕 李雪丹 杨峰 《中国学校卫生》 CAS CSCD 北大核心 2025年第4期519-523,共5页
目的了解青岛市母亲为适龄女生接种人乳头瘤病毒(HPV)的意愿及影响因素,为开展有针对性的健康教育提供理论基础。方法采用多阶段随机抽样方法,于2023年3—12月选取青岛市2244名12~14岁初中女生的母亲开展横断面研究。采用Mann-Whitney ... 目的了解青岛市母亲为适龄女生接种人乳头瘤病毒(HPV)的意愿及影响因素,为开展有针对性的健康教育提供理论基础。方法采用多阶段随机抽样方法,于2023年3—12月选取青岛市2244名12~14岁初中女生的母亲开展横断面研究。采用Mann-Whitney U检验比较组间差异以及Logistic回归分析母亲为适龄女儿接种HPV疫苗意愿影响因素。结果愿意为女儿接种HPV疫苗的母亲有2002名(89.22%),自身已全程接种或准备全程接种的母亲1539名(68.58%),愿意为女儿接种的母亲认知得分为10(8,11)分。多因素Logistic回归分析显示,>45岁(OR=0.19)、家庭年总收入(6~<15)万元(OR=0.65)、(15~<30)万元(OR=0.58)、(30~50)万元(OR=0.22)、认知得分越高(OR=0.90)的母亲更愿意为女儿接种;学历为大专或本科(OR=1.66)、从不进行HPV筛查或偶尔筛查(OR=1.58)、不愿意接种、不准备全程接种或超龄未接种(OR=7.13)、不担心女儿感染(OR=2.54)、女儿处于非青春期(OR=1.93)的母亲更不愿意为女儿接种(P值均<0.05)。不愿意接种的主要原因是担心疫苗安全(65.06%),其次为母亲认为“孩子年龄太小,长大后再接种”(13.25%)。结论青岛市适龄女生母亲为女儿接种HPV疫苗意愿较高,意愿受母亲自身接种情况、认知水平、女儿发育时期等因素影响。建议加强针对性健康教育,提高母亲认知水平和接受程度,提升HPV疫苗接种率。 展开更多
关键词 母亲 乳头状瘤病毒疫苗 态度 回归分析 学生 女(雌)性
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Higher alcohol synthesis over Cu-Fe composite oxides with high selectivity to C2+OH 认领 引用 被引量：14
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作者 Zhenghong Bao Kang Xiao +5 位作者 Xingzhen Qi Xinxing Wang Liangshu Zhong Kegong Fang Minggui Lin Yuhan Sun 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2013年第1期107-113,共7页
Cu-Fe composite oxides were prepared by co-precipitation method and tested for higher alcohol synthesis from syngas. The selectivity to C2＋OH and C6＋OH in alcohol distribution was very high while the methane product... Cu-Fe composite oxides were prepared by co-precipitation method and tested for higher alcohol synthesis from syngas. The selectivity to C2＋OH and C6＋OH in alcohol distribution was very high while the methane product fraction in hydrocarbon distribution was rather low, demonstrating a promising potential in higher alcohols synthesis from syngas. The distribution of alcohols and hydrocarbons approximately obeyed Anderson-Schulz-Flory distribution with similar chain growth probability, indicating alcohols and hydrocarbons derived from the same intermediates. The effects of Cu/Fe molar ratio, reaction temperature and gas hourly space velocity （GHSV） on catalytic performance were studied in detail. The sample with a Cu/Fe molar ratio of 10/1 exhibited the best catalytic performance. Higher reaction temperature accelerated water-gas-shift reaction and led to lower total alcohols selectivity. GHSV showed great effect on catalytic performance and higher GHSV increased the total alcohol selectivity, indicating there existed visible dehydration reaction of alcohol into hydrocarbon. 展开更多
关键词 higher alcohol synthesis syngas Cu-Fe composite oxides molar ratio GHSV
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T188K-Familial Creutzfeldt–Jacob Disease, Predominant Among Chinese, has a Reactive Pattern in CSF RT-QuIC Different from D178N-Fatal Familial Insomnia and E200K-Familial CJD 认领 引用 被引量：9
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作者 Kang Xiao Qi Shi +6 位作者 Wei Zhou Bao-Yun Zhang Yuan Wang Cao Chen Yue Ma Chen Gao Xiao-Ping Dong 《Neuroscience Bulletin》 SCIE CAS CSCD 2019年第3期519-521,共3页
Dear Editor,Human prion diseases consist of sporadic, genetic/familial, and acquired forms. The familial form accounts for 5%-15% of all human prion diseases, including familial Creutzfeldt- Jacob disease (fCJD), Gers... Dear Editor,Human prion diseases consist of sporadic, genetic/familial, and acquired forms. The familial form accounts for 5%-15% of all human prion diseases, including familial Creutzfeldt- Jacob disease (fCJD), Gerstmann-Straussler-Scheinker syndrome, and fatal familial insomnia (FFI)[1-3]. All genetic prion diseases are directly associated with mutations (point-mutation or insertion) in the PRNP gene located on human chromosome 20 and encodes prion protein (PrP). So far,>55 mutations in the PRNP gene have been described [4]. Some PRNP mutations and their related genetic prion diseases have been reported worldwide, while others show clear region- or ethnicity-associated features. 展开更多
关键词 Human prion diseases sporadic ethnicity-associated features
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Genetic Prion Disease:Insight from the Features and Experience of China National Surveillance for Creutzfeldt-Jakob Disease 认领 引用 被引量：7
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作者 Qi Shi Cao Chen +8 位作者 Kang Xiao Wei Zhou Li-Ping Gao Dong-Dong Chen Yue-Zhang Wu Yuan Wang Chao Hu Chen Gao Xiao-Ping Dong 《Neuroscience Bulletin》 SCIE CAS CSCD 2021年第11期1570-1582,共13页
Human genetic prion diseases(gPrDs)are directly associated with mutations and insertions in the PRNP(Prion Protein)gene.We collected and analyzed the data of 218 Chinese gPrD patients identified between Jan 2006 and J... Human genetic prion diseases(gPrDs)are directly associated with mutations and insertions in the PRNP(Prion Protein)gene.We collected and analyzed the data of 218 Chinese gPrD patients identified between Jan 2006 and June 2020.Nineteen different subtypes were identified and gPrDs accounted for 10.9%of all diagnosed PrDs within the same period.Some subtypes of gPrDs showed a degree of geographic association.The age at onset of Chinese gPrDs peaked in the 50–59 year group.Gerstmann–Sträussler–Scheinker syndrome(GSS)and fatal familial insomnia(FFI)cases usually displayed clinical symptoms earlier than genetic Creutzfeldt–Jakob disease(gCJD)patients with point mutations.A family history was more frequently recalled in P105L GSS and D178N FFI patients than T188K and E200K patients.None of the E196A gCJD patients reported a family history.The gCJD cases with point mutations always developed clinical manifestations typical of sporadic CJD(sCJD).EEG examination was not sensitive for gPrDs.sCJD-associated abnormalities on MRI were found in high proportions of GSS and gCJD patients.CSF 14-3-3 positivity was frequently detected in gCJD patients.Increased CSF tau was found in more than half of FFI and T188K gCJD cases,and an even higher proportion of E196A and E200K gCJD patients.63.6%of P105L GSS cases showed a positive reaction in cerebrospinal fluid RT-QuIC.GSS and FFI cases had longer durations than most subtypes of gCJD.This is one of the largest studies of gPrDs in East Asians,and the illness profile of Chinese gPrDs is clearly distinct.Extremely high proportions of T188K and E196A occur among Chinese gPrDs;these mutations are rarely reported in Caucasians and Japanese. 展开更多
关键词 Genetic prion disease Mutation Surveillance Creutzfeldt-Jakob disease Gerstmann-Sträussler-Scheinker syndrome Fatal familial insomnia
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IP10, KC and M-CSF Are Remarkably Increased in the Brains from the Various Strains of Experimental Mice Infected with Different Scrapie Agents 认领 引用 被引量：5
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作者 Jia Chen Cao Chen +11 位作者 Chao Hu Lian Liu Ying Xia Lin Wang Wei Yang Hai-Yan Wu Wei Zhou Kang Xiao Qi Shi Yuezhang Wu Zhi-Bao Chen Xiao-Ping Dong 《Virologica Sinica》 SCIE CAS CSCD 2020年第5期614-625,共12页
Activation of inflammatory cells and upregulations of a number of cytokines in the central nervous system(CNS)of patients with prion diseases are frequently observed.To evaluate the potential changes of some brain cyt... Activation of inflammatory cells and upregulations of a number of cytokines in the central nervous system(CNS)of patients with prion diseases are frequently observed.To evaluate the potential changes of some brain cytokines that were rarely addressed during prion infection,the levels of 17 different cytokines in the brain homogenates of mice infected with different scrapie mouse-adapted agents were firstly screened with Luminex assay.Significant upregulations of interferon gamma-induced protein 10(IP10),keratinocyte chemoattractant(KC)and macrophage colony stimulating factor(M-CSF)were frequently detected in the brain lysates of many strains of scrapie infected mice.The upregulations of those three cytokines in the brains of scrapie infected mice were further validated by the individual specific ELISA and immunohistochemical assay.Increased specific mRNAs of IP10,M-CSF and KC in the brains of scrapie infected mice were also detected by the individual specific qRT-PCRs and IP10-specific digital PCR.Dynamic analyses of the brain samples collected at different time points post infection revealed the time-dependent increases of those three cytokines,particularly IP10 during the incubation period of scrapie infection.In addition,we also found that the levels of IP10 in cerebral spinalfluid(CSF)of 45 sporadic Creutzfeldt–Jakob disease(sCJD)patients were slightly but significantly higher than those of the cases who were excluded the diagnosis of prion diseases.These data give us a better understanding of inflammatory reaction during prion infection and progression of prion disease. 展开更多
关键词 Prion Cytokines Interferon gamma-induced protein 10(IP10) Keratinocyte chemoattractant(KC) Macrophage colony stimulating factor(M-CSF)
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基于人在回路策略的在线置信规则库疾病诊断方法 认领 引用 被引量：2
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作者 韩文策 康潇 +3 位作者 李红宇 贺维 周国辉 卜祥峰 《计算机工程》 CAS CSCD 北大核心 2025年第1期321-331,共11页
在医疗实践中,收集病人的生理指标往往是诊断疾病的关键。然而,现实中病人的生理数据往往是不确定和模糊的。置信规则库(BRB)是一种专家系统方法,它通过结合专家知识将数据转化为置信分布,从而有效地处理各种不确定性和模糊性信息。然而... 在医疗实践中,收集病人的生理指标往往是诊断疾病的关键。然而,现实中病人的生理数据往往是不确定和模糊的。置信规则库(BRB)是一种专家系统方法,它通过结合专家知识将数据转化为置信分布,从而有效地处理各种不确定性和模糊性信息。然而,目前基于BRB的疾病诊断模型仍依赖于离线训练方法,这不足以满足疾病诊断环境中的动态实时要求。此外,其他领域现有的在线模型也存在训练数据样本数量爆炸式增长和样本不平衡的问题。因此,提出一种基于人在回路策略的在线置信规则库疾病诊断方法。首先,将传统的离线训练BRB疾病诊断模型改进为在线训练模型,使模型能够根据不同患者的生理指标实现动态增长。其次,在在线学习的BRB模型中,提出了一种人在回路算法,以增强专家的决策能力,有效解决传统在线模型中训练样本爆炸式增长、模型输出过拟合和样本不平衡等问题。最后,通过对慢性肾病分级、丙型肝炎预测、乳腺癌诊断和糖尿病诊断的实验结果验证了该方法的有效性和优越性。 展开更多
关键词 在线学习 人在回路 置信规则库 疾病诊断 样本分析
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Insights into reactive oxygen species formation induced by water-soluble organic compounds and transition metals using spectroscopic method 认领 引用 被引量：3
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作者 Tianyi Zhao Yu Yan +7 位作者 Bian Zhou Xuezhen Zhong Xiaoyu Hu Lijia Zhang Peng Huo Kang Xiao Yuanxun Zhang Yang Zhang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2023年第2期835-845,共11页
Ambient particulate matter(PM)can cause adverse health effects via their ability to produce Reactive Oxygen Species(ROS).Water-Soluble Organic Compounds(WSOCs),a complex mixture of organic compounds which usually coex... Ambient particulate matter(PM)can cause adverse health effects via their ability to produce Reactive Oxygen Species(ROS).Water-Soluble Organic Compounds(WSOCs),a complex mixture of organic compounds which usually coexist with Transition Metals(TMs)in PM,have been found to contribute to ROS formation.However,the interaction between WSOCs and TMs and its effect on ROS generation are still unknown.In this study,we examined the ROS concentrations of V,Zn,Suwannee River Fulvic Acid(SRFA),Suwannee River Humic Acid(SRHA)and the mixtures of V/Zn and SRFA/SRHA by using a cell-free 2’,7’-Dichlorodihydrofluorescein(DCFH)assay.The results showed that V or Zn synergistically promoted ROS generated by SRFA,but had an antagonistic effect on ROS generated by SRHA.Fluorescence quenching experiments indicated that V and Zn were more prone to form stable complexes with aromatic humic acid-like component(C1)and fulvic acidlike component(C3)in SRFA and SRHA.Results suggested that the underlying mechanism involving the fulvic acid-like component in SRFA more tending to complex with TMs to facilitate ROS generation throughπelectron transfer.Our work showed that the complexing ability and complexing stability of atmospheric PM organics with metals could significantly affect ROS generation.It is recommended that the research deploying multiple analytical methods to quantify the impact of PM components on public health and environment is needed in the future. 展开更多
关键词 Water-soluble organic carbons Transition metals Reactive oxygen species Excitation-emission matrix
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Atomic modulation of Fe‐Co pentlandite coupled with nitrogen‐doped carbon sphere for boosting oxygen catalysis 认领 引用 被引量：2
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作者 Si‐Jie Li Yong Xie +5 位作者 Bi‐Lin Lai Yingmin Liang Kang Xiao Ting Ouyang Nan Li Zhao‐Qing Liu 《Chinese Journal of Catalysis》 SCIE EI CAS CSCD 2022年第6期1502-1510,共9页
Reversible oxygen reaction plays a crucial role in rechargeable battery systems,but it is limited by the slow reaction kinetics.Herein,the ionic modulation of cobalt pentlandite coupled with nitrogen‐doped bowl‐like... Reversible oxygen reaction plays a crucial role in rechargeable battery systems,but it is limited by the slow reaction kinetics.Herein,the ionic modulation of cobalt pentlandite coupled with nitrogen‐doped bowl‐like hollow carbon sphere is well designed on octahedral and tetrahedral sites.The robust FexCo9−xS8‐NHCS‐V with iron replacing at the octahedron possesses prolonged metal sulfur bond and exhibits excellent bifunctional electrocatalytic performance towards oxygen reduction reaction(ORR,E1/2=0.80 V vs.RHE)and excellent oxygen evolution reaction(OER,Ej=10=1.53 V vs.RHE)in 0.1 mol/L KOH.Accordingly,a rechargeable Zn‐air battery of FexCo9−xS8‐NHCS‐V cathode endows high energy efficiency(102 mW cm−2),and a microbial fuel cell achieves a high‐power density(791±42 mW m−2),outperforming the benchmark Pt/C catalyst. 展开更多
关键词 Oxygen electrocatalysis Transition metal sulfide Nitrogen‐doped carbon Pentlandite structure Zinc‐air battery
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Spatial heterogeneity and compositional profiles of dissolved organic matter in farmland soils across China' Mainland 认领 引用 被引量：1
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作者 Bingjun Han Liyuan Chen +6 位作者 Kang Xiao Yang Liu Dong Cao Lu Yu Yujun Li Shu Tao Wenxin Liu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2024年第3期593-603,共11页
Dissolved organic matter(DOM) plays an essential role in many geochemical processes,however its complexity, chemical diversity, and molecular composition are poorly understood. Soil samples were collected from 500 veg... Dissolved organic matter(DOM) plays an essential role in many geochemical processes,however its complexity, chemical diversity, and molecular composition are poorly understood. Soil samples were collected from 500 vegetable fields in administrative regions of China' Mainland, of which 122 were selected for further investigation. DOM properties were characterized by three-dimensional excitation-emission matrix(3D-EEM) fuorescence spectroscopy and Fourier transform ion cyclotron resonance mass spectrometry(FTICRMS)(field intensity is 15 Tesla). Our results indicated that the main constituents were UVA humic-like substances, humic-like substances, fulvic acid-like substances, and tyrosine-like substances. A total of 10,989 molecular formulae with a mass range of 100.04 to 799.59 Da were detected, covering the mass spectrometric information of the soil samples from 27 different regions. CHO and CHON molecules were dominant in DOM, whereas lignin, tannins,and aromatic substances served as the main components. The results of cluster analysis revealed that the soil properties in Jiangxi Province were considerably different from those in other regions. The key backgrounds of the DOM molecular characteristics in the vegetablefield soil samples across China' Mainland were provided at the molecular level, with large abundance and great variability. 展开更多
关键词 Dissolved organic matter(DOM) Fourier transform ion cyclotron resonance mass(FTICR-MS) Excitation-emission matrix(EEM) Vegetable-field soils China' Mainland
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Single-phase bimetal sulfide or metal sulfide heterojunction:Which one is better for reversible oxygen electrocatalyst? 认领 引用 被引量：1
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作者 Jingjing Cai Huijun Liu +5 位作者 Yulin Luo Yuqing Xiong Lizhu Zhang Sheng Wang Kang Xiao Zhao-Qing Liu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2022年第11期420-428,I0012,共9页
Bimetallic sulfides,integrating the merits of individual components,are ideal structures for efficient electrocatalysis.However,for bimetallic sulfides including metal sulfide heterojunctions(MSH)and singlephase bimet... Bimetallic sulfides,integrating the merits of individual components,are ideal structures for efficient electrocatalysis.However,for bimetallic sulfides including metal sulfide heterojunctions(MSH)and singlephase bimetallic sulfides(SBS),it is still unclear about which one has better catalytic activity toward reversible oxygen catalysis and its difference on catalytic mechanism.In this work,we demonstrate a bimetallic sulfide electrocatalyst that could transform from metal sulfide heterojunction(CoS/FeS)to single-phase bimetallic sulfide(CoFeS2)through a facile temperature control strategy.The single-phase bimetallic sulfide(CoFeS2)affords high intrinsic activity,fast reaction kinetics and superior durability toward oxygen evolution reaction(OER)and oxygen reduction reaction(ORR).Density functional theory(DFT)simulations reveal that the(CoFeS2)has homogeneous electron distribution of the CoFeS2structure,improves the central energy level of d band,and optimizes the O*and OOH*intermediate and efficiently reduces the energy barrier of the reaction rate-determining step(RDS).The assembled rechargeable zincair battery is more stable than the Pt/C and IrO2 assemblies due to the excellent electrocatalytic activity and stability of CoFeS2/NC,suggesting that it has potential for use in practical applications. 展开更多
关键词 Metal sulfide Sulfide heterojunction OER ORR Zinc-air batteries
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Roles of membrane and organic fouling layers on the removal of endocrine disrupting chemicals in microfiltration 认领 引用 被引量：1
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作者 Wenchao Xue Kang Xiao +1 位作者 Peng Liang Xia Huang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2018年第10期176-184,共9页
To understand the adsorption behavior of endocrine disrupting chemicals（EDCs） is important for enhancing the treatment performance and preventing potential secondary pollution caused by EDCs desorption in a microfil... To understand the adsorption behavior of endocrine disrupting chemicals（EDCs） is important for enhancing the treatment performance and preventing potential secondary pollution caused by EDCs desorption in a microfiltration system. The dynamic adsorption of four representative EDCs, namely estriol（E3）, 17β-estradiol（E2）, 17α-ethynylestradiol（EE2）, and 4-nonylphenol（4-NP） in a microfiltration system was investigated using the Thomas＇ model.The product of the equilibrium constant and the total adsorption capacity of the membrane,Ka, for E3, E2, EE2, and 4-NP were 4.91, 9.78, 15.6, and 826, respectively, strongly correlating with the compound octanol–water partition coefficient（KOW）. Adsorption appeared to be enhanced when organic fouling formed on the surface of membrane, indicating the role of an additional adsorption column for EDCs acted by a fouling layer in microfiltration. Results of a comparison between the Ka values for clean membrane and fouled membrane illustrated that the significant contribution made by fouling layers may be attributed to the foulant layer＇s hydrophobicity（in the case of calcium humate layer） and thickness（in the case of calcium alginate layer）. This study provided a novel perspective to quantitatively analyze the dynamic adsorption behavior of trace pollutants in membrane process. 展开更多
关键词 Endocrine disrupting chemicals Microfiltration membrane Dynamic adsorption Thomas＇ model Organic membrane fouling
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多学科诊疗协作下巨大股前外侧皮瓣修复颊部鳞状细胞癌复发1例 认领 引用 被引量：1
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作者 向峰 康霄 +1 位作者 鲁立光 伍栋 《口腔颌面外科杂志》 CAS 2025年第1期70-74,共5页
目的:观察分析1例多学科诊疗(multi-disciplinary team,MDT)协作下巨大股前外侧皮瓣修复颊部鳞状细胞癌复发案例。方法:2020年8月,在口腔-头颈MDT协作下对1例晚期颊部鳞状细胞癌复发患者进行术前辅助化疗、手术治疗、术后辅助化疗及放疗... 目的:观察分析1例多学科诊疗(multi-disciplinary team,MDT)协作下巨大股前外侧皮瓣修复颊部鳞状细胞癌复发案例。方法:2020年8月,在口腔-头颈MDT协作下对1例晚期颊部鳞状细胞癌复发患者进行术前辅助化疗、手术治疗、术后辅助化疗及放疗,并对患者预后及修复重建效果进行随访观察。结果:患者术后伤口一期愈合,顺利完成术后辅助化疗及放疗,术后2年半复查无复发。与传统治疗相比,MDT大大缩短了治疗周期,提高了患者生存率及满意度。结论:对于复发、晚期等难治性口腔癌患者,可在MDT模式下制定“个性化”治疗方案,该方法值得临床推广。 展开更多
关键词 口腔癌 多学科诊疗 放化疗 股前外侧皮瓣
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三维蒙皮点阵结构宏微观协同优化设计 认领 引用 被引量：1
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作者 李洁 康骁 +3 位作者 刘克垅 张希洋 吴亚鹏 李营 《宇航总体技术》 CSCD 2025年第4期7-15,共9页
点阵结构因其优异的力学性能在航空航天领域发挥着不可替代的作用,是实现结构轻量化的重要途径。针对传统点阵均匀化方法在杆件直径增大时力学性能表达不精确的问题,提出了一种改进方法,并实现了三维蒙皮点阵结构的高效、高刚度、轻量... 点阵结构因其优异的力学性能在航空航天领域发挥着不可替代的作用,是实现结构轻量化的重要途径。针对传统点阵均匀化方法在杆件直径增大时力学性能表达不精确的问题,提出了一种改进方法,并实现了三维蒙皮点阵结构的高效、高刚度、轻量化设计。基于修正的均匀化理论,建立了点阵结构相对杨氏模量与相对密度的精确解析表达式。将修正的理论模型与有限元仿真相结合,并耦合多目标优化算法,进而提出了一种针对三维蒙皮点阵结构的宏微观协同优化方法。将修正理论模型的计算结果与有限元仿真及试验结果进行对比,相对误差控制在15%以内,显著提升了点阵结构力学性能的表征精度。通过宏观分层设计和微观几何参数的优化,最终实现结构质量减小61%的目标,达到了三维蒙皮点阵结构的刚度与质量协同优化设计目标。结果表明,修正后的理论方法有效提升了点阵结构力学性能的表征精度,确保了仿真结果的可靠性。宏微观协同优化策略成功克服了三维蒙皮点阵结构因几何复杂性导致的优化难题,显著提高了优化效率,实现了高刚度轻量化设计,为性能驱动型复杂航空航天结构的轻量化设计提供了有效方法。 展开更多
关键词 三维蒙皮点阵 多目标优化 等效模型 轻量化设计
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