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Revealing inheritance of a Xinjiang isolate BGTB-1 of Puccinia striiformis f.sp.tritici and the shift of pathogenicity from avirulence to virulence at heterozygous AvrYr5 locus 认领 引用
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作者 Lin Wang Fei Liu +3 位作者 Yumeng Bian Mudi Sun Zhensheng Kang Jie Zhao 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2026年第2期744-755,共12页
In China,Xinjiang is a relatively independent epidemic region of wheat stripe rust,caused by Puccinia striiformis f.sp.tritici,due to great population genetic divergence of Xinjiang with other inland epidemic regions.... In China,Xinjiang is a relatively independent epidemic region of wheat stripe rust,caused by Puccinia striiformis f.sp.tritici,due to great population genetic divergence of Xinjiang with other inland epidemic regions.In this region,race evolution was usually slower than inland populations.However,many new races have recently been found,and therefore,it is necessary for more understanding of the virulence evolution of the Xinjiang population.So,in this study,a 65 sexual progenies,derived from a Xinjiang single-urediospore isolate BGTB-1 of P.striiformis f.sp.tritici by selfing on alternate host barberry(Berberis aggregata).It was phenotyped on the 25 single Yr lines,and genotyped by 19 kompetitive allele-specific PCRsingle nucleotide polymorphism(KASP-SNP) markers.As a result,the 65 progenies were identified as 56 various virulence patterns(VPs),and neither of which was identical to the parental isolate,showed 100% virulence variation.Compared with the parental isolate,of all progenies,39(60.0%) had increased virulence,and 18(27.7%) had decreased virulence.All progenies exhibited avirulence to Yr10,Yr15,Yr32,and YrTr1 loci,and avirulence and virulence segregation at the remaining 21 Yr resistance loci.The results showed avirulence to Yr5,Yr7,and Yr76(A:V≈3:1) loci is controlled by a single dominant gene,and that to Yr6,Yr25,and Yr44(A:V≈1:3) loci by a single recessive gene.However,avirulence to the remaining 15 resistant loci including Yr1,Yr2,Yr3,Yr4,Yr8,Yr9,Yr17,Yr26(=Yr24),Yr28,Yr29,Yr43,YrSP,Yr27,YrA,and YrExp2,with various avirulence and virulence segregation ratios,is controlled by two genes with different gene effects,indicating complex genetic traits of the parental isolate.Totally,65 dissimilar genotypes detected among progenies using overall molecular markers,by which a linkage map was constructed,with a genetic distance of 441.0 cM.Interestingly,although the parental isolate was avirulent to Yr5,but 17 progenies showed virulence,showing the change of pathogenicity from avirulence to virulence at this resistance locus.It was for the first time to report that progenies with virulence to Yr5 produced sexually from avirulent parental isolate at this resistance locus.To our knowledge,this study offers an insight into inheritance,sexual reproduction and virulence variation of P.striiformis f.sp.tritici in Xinjiang,facilitating us to understand evolution of the rust pathogen in this region and accounting for Xinjiang population distinguished form other inland populations.Additionally,it is necessary to further confirm the roles of sexual reproduction in the emergence of new races and affecting population genetic diversity of P.striiformis f.sp.tritici under natural conditions in Xinjiang. 展开更多
关键词 wheat yellow rust Puccinia striiformis f.sp.tritici sexual reproduction virulence variation new race SNP Yr5 Xinjiang
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Expert consensus on the detection and clinical application of tumor mutational burden 认领 引用
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作者 Zhenying Guo Chunwei Xu +168 位作者 Shirong Zhang Yue Hao Xiaotong Hu Ming Zhao Chan Xiang Yingshi Piao Pingli Sun Xueping Xiang Jing Zhao Huanwen Wu Weixing Li Jinpu Yu Jingping Yuan Shuangshuang Wang Cong Wang Yun Gu Bingjian Lv Liping Zhang Yueping Liu Xiaobin Cui Weizhong Gu Yining Li Wei Wang Wenjun Yang Weiguo Long Jingjing Xiang Hong Mou Biao Liu Huajuan Ruan Yubin Wang Yongjie Zhu Feng Wang Zhonghua Wang Xiaomin Feng Xing Liu Peng Li Min Deng Bin Lian Lili Mao Qian Wang Wenxian Wang Zhengbo Song Ziming Li Wenzhao Zhong Zhijie Wang Shengxiang Ren Wenfeng Fang Yongchang Zhang Jingjing Liu Xiuyu Cai Anwen Liu Wen Li Ping Zhan Hongbing Liu Tangfeng Lv Liyun Miao Lingfeng Min Yu Chen Yu Zhang Feng Wang Zhansheng Jiang Gen Lin Long Huang Xingxiang Pu Rongbo Lin Weifeng Liu Chuangzhou Rao Dongqing Lv Zongyang Yu Peng Shen Xiaoyan Li Chuanhao Tang Chengzhi Zhou Junping Zhang Junli Xue Hui Guo Qian Chu Rui Meng Jingxun Wu Rui Zhang Jin Zhou Zhengfei Zhu Yongheng Li Hong Qiu Fan Xia Yuanyuan Lu Xiaofeng Chen Rui Ge Enyong Dai Yu Han Jian Zhang Yinghua Ji Xianbin Liang Hongmei Zhang Xuelei Ma Xuewen Liu Yu Yao Peng Luo Weiwei Pan Fei Pang Fan Wu Dejian Gu Li Wang Liping Wang Youcai Zhu Li Lin Weiwen Li Xinqing Lin Jing Cai Ling Xu Jisheng Li Xiaodong Jiao Kainan Li Jia Wei Huijing Feng Lin Wang Yingying Du Wang Yao Xuefei Shi Xiaomin Niu Dongmei Yuan Yanwen Yao Yinbin Zhang Binbin Song Wenfeng Li Jianfei Fu Hong Wang Mingxiang Ye Dong Wang Zhaofeng Wang Qing Ji Yuan Fang Qing Wei Zhen Wang Bin Wan Donglai Lv Xiaofeng Li Shengjie Yang Jing Kang Jiatao Zhang Chao Zhang Lin Shi Yina Wang Bihui Li Zhang Zhang Ke Wang Zhefeng Liu Nong Yang Lin Wu Xiaobing Chen Gu Jin Zhongwu Li Miao Li Guansong Wang Jiandong Wang Meiyu Fang Yong Fang Xiaojia Wang Jing Chen Yiping Zhang Xixu Zhu Yi Shen Shenglin Ma Biyun Wang Lu Si Yong Song Yuanzhi Lu Aijun Liu Yuchen Han 《Cancer Biology & Medicine》 SCIE CAS CSCD 2026年第2期218-246,共29页
As an emerging biomarker,tumor mutational burden(TMB)has attracted increasing attention from clinicians in predicting the efficacy of tumor immunotherapy.Currently,TMB is detected primarily by whole-exome sequencing o... As an emerging biomarker,tumor mutational burden(TMB)has attracted increasing attention from clinicians in predicting the efficacy of tumor immunotherapy.Currently,TMB is detected primarily by whole-exome sequencing or targeted panel sequencing on high-throughput sequencing platforms.However,the lack of uniformity in detection methods,threshold settings,and reporting formats,as well as the significant differences in TMB values among different cancer types,have hindered the standardized application of this biomarker in clinical practice.This consensus focuses on the definition,standardization of detection,clinical significance,and limitations of TMB,and provides consensus recommendations for the clinical application of TMB in real-world practice in China.This consensus is aimed at helping clinicians and laboratory personnel understand the clinical significance and testing standards of TMB,promoting more accurate interpretation of test results,and improving patient care. 展开更多
关键词 Biomarkers tumor mutational burden tumor immunotherapy targeted panel sequencing whole-exome sequencing
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Buckling and Dynamical Behaviors of Hard Magnetic Soft Pipe Conveying Fluid Under Distributed Spring Constraint 认领 引用
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作者 Jiachun Hu Dilong Ma +3 位作者 Runqing Cao Wei Chen Huliang Dai Lin Wang 《Acta Mechanica Solida Sinica》 SCIE EI CSCD 2026年第1期52-64,共13页
Fluid-conveying pipes have been widely used in diverse engineering fields,particularly in aerospace systems,nuclear power plants,oil transportation infrastructure,and biomedical devices.The recent advancements in 3D p... Fluid-conveying pipes have been widely used in diverse engineering fields,particularly in aerospace systems,nuclear power plants,oil transportation infrastructure,and biomedical devices.The recent advancements in 3D printing and materials science have increased research interest in the stability and vibration characteristics of slender pipes fabricated from hard magnetic soft(HMS)materials for magnetic control applications.Although several theoretical investigations have been conducted on magnetically controlled cantilevered fluid-conveying pipes,the understanding of their dynamical behavior in vascular environments remains incomplete.In this study,we investigate the buckling and dynamical behaviors of an HMS pipe under the combined effects of an applied magnetic field and nonlinear distributed spring constraints.By solving the nonlinear governing equation,natural frequencies,critical flow velocities,buckling displacements,and dynamic responses of the HMS pipe conveying fluid are obtained.The analysis reveals that the addition of distributed spring constraints leads to a substantial reduction in both buckling and dynamic displacements of the pipe system.Under constant magnetic field conditions,the pipe exhibits static deformation characteristics even when exposed to flow velocities exceeding the critical threshold for buckling instability.When subjected to an alternating magnetic field,the pipe system exhibits periodic oscillatory behavior across a wide range of flow velocities.This periodic response is characterized by displacement variations that show direct correlation with changes in the magnetic declination angle.Notably,nonlinear resonance phenomena associated with the first-mode natural frequency can occur even when the flow velocity is below the threshold for buckling instability.These results demonstrate that both magnetic field strength and declination angle offer a possible means for adjusting the stability,buckling behavior,and dynamic response of an HMS pipe. 展开更多
关键词 Hard magnetic soft material Pipe conveying fluid Distributed spring constraint Dynamical behavior Buckling instability Alternating magnetic field
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Probabilistic analysis of settlement characteristics induced by shield tunnelling in sandy cobble soil considering spatial variability 认领 引用 被引量：1
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作者 Fan WANG Pengfei LI +2 位作者 Xiuli DU Jianjun MA Lin WANG 《Journal of Zhejiang University-SCIENCE A》 SCIE EI CAS CSCD 2025年第8期771-786,共16页
Sandy cobble soil exhibits pronounced heterogeneity.The assessment of the uncertainty surrounding its properties is crucial for the analysis of settlement characteristics resulting from volume loss during shield tunne... Sandy cobble soil exhibits pronounced heterogeneity.The assessment of the uncertainty surrounding its properties is crucial for the analysis of settlement characteristics resulting from volume loss during shield tunnelling.In this study,a series of probabilistic analyses of surface and subsurface settlements was conducted considering the spatial variability of the friction angle and reference stiffness modulus,under different volumetric block proportions(Pv)and tunnel volume loss rates(ηt).The non-intrusive random finite difference method was used to investigate the probabilistic characteristics of maximum surface settlement,width of subsurface settlement trough,maximum subsurface settlement,and subsurface soil volume loss rate through Monte Carlo simulations.Additionally,a comparison between stochastic and deterministic analysis results is presented to underscore the significance of probabilistic analysis.Parametric analyses were subsequently conducted to investigate the impacts of the key input parameters in random fields on the settlement characteristics.The results indicate that scenarios with higher Pv or greaterηt result in a higher dispersion of stochastic analysis results.Neglecting the spatial variability of soil properties and relying solely on the mean values of material parameters for deterministic analysis may result in an underestimation of surface and subsurface settlements.From a probabilistic perspective,deterministic analysis alone may prove inadequate in accurately capturing the volumetric deformation mode of the soil above the tunnel crown,potentially affecting the prediction of subsurface settlement. 展开更多
关键词 Shield tunnels Sandy cobble soil Settlement characteristics Spatial variability Probabilistic analysis
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Designing electrolyte with multi-ether solvation structure enabling low-temperature sodium ion capacitor 认领 引用 被引量：1
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作者 Dongming Liu Mengfan Pei +6 位作者 Xin Jin Lin Wang Wanyuan Jiang Borui Li Runyue Mao Xigao Jian Fangyuan Hu 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2025年第4期451-460,共10页
Sodium-ion hybrid capacitors(SICs),which combine the high energy density of batteries with the high power density and long cycle life of capacitors,are considered promising next-generation energy storage devices.Ensur... Sodium-ion hybrid capacitors(SICs),which combine the high energy density of batteries with the high power density and long cycle life of capacitors,are considered promising next-generation energy storage devices.Ensuring the performance of SICs in low-temperature environments is crucial for applications in high-altitude cold regions,where the desolvation process of Na+and the transport process in the solid electrolyte interphase(SEI)are determinant.In this paper,we proposed a multi-ether modulation strategy to construct a solvation sheath with multi-ether participation by modulating the coordination of Na+and solvents.This unique solvation sheath not only reduces the desolvation energy barrier of Na+,but more importantly forms a Na2O-rich inorganic SEI and enhances the ionic dynamics of Na+.Benefiting from the excellent solvation structure design,SICs prepared with this electrolyte can achieve energy density of up to 178 Wh·kg-1 and ultra-high power density of 42390 W·kg-1 at room temperature.Notably,this SIC delivers record-high energy densities of 149 Wh·kg-1 and 119 Wh·kg-1 as well as power densities of up to 25200 W·kg-1 and 24591 W·kg-1 at−20℃ and−40℃,respectively.This work provides new ideas for the development of high-performance SICs for low-temperature operating environments. 展开更多
关键词 sodium ion capacitors solvated structure Na2O-rich SEI low operating temperature
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Phase equilibria of ternary system RbCl-polyethylene glycol(PEG6000)-H2O at T=(288.2,298.2,and 308.2)K:Measurement,correlation,and thermodynamic modeling 认领 引用
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作者 Shan Feng Maolan Li +2 位作者 Xudong Yu Lin Wang Qin Huang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2025年第5期105-114,共10页
The phase equilibria relationship of the system RbCl-PEG6000-H2O were investigated at temperatures of 288.2,298.2,and 308.2 K,the compositions of solid-liquid equilibria(SLE)and liquid-liquid equilibria(LLE)were deter... The phase equilibria relationship of the system RbCl-PEG6000-H2O were investigated at temperatures of 288.2,298.2,and 308.2 K,the compositions of solid-liquid equilibria(SLE)and liquid-liquid equilibria(LLE)were determined.The complete phase diagrams,binodal curve diagrams,and tie-line diagrams were all plotted.Results show that both solid-liquid equilibria and liquid-liquid equilibria relationships at each studied temperature.The complete phase diagrams at 288.2 K,298.2 K and 308.2 K consist of six phase regions:unsaturated liquid region(L),two saturated solutions with one solid phase of RbCl(L_S),one saturated liquid phase with two solid phases of PEG6000 and RbCl(2S+L),an aqueous two-phase region(2L),and a region with two liquids and one solid phase of RbCl(2L_S).With the increase in temperature,the layering ability of the aqueous two-phase system increases,and both regions(2L)and(2L_S)increase.The binodal curves were fitted using the nonlinear equations proposed by Mistry,Hu,and Jayapal.Additionally,the tie-line data were correlated with the Othmer-Tobias,Bancroft,Hand,and Bachman equations.The liquid-liquid equilibria at 288.2 K,298.2 K and 308.2 K were calculated using the NRTL model.The findings confirm that the experimental and calculated values are in close agreement,demonstrating the model’s effectiveness in representing the system’s behavior. 展开更多
关键词 Phase equilibria Solubility Thermodynamic properties Liquid-liquid phase equilibria Solid-liquid phase equilibria NRTL model
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Upper-ocean cooling rate of the South China Sea in response to extreme cold surges and weak cold-air invasions 认领 引用
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作者 Weiwei Zhang Dongxiao Wang +3 位作者 Marco Y.-T.Leung Lin Wang Jinchi Xie Wen Zhou 《Atmospheric and Oceanic Science Letters》 CSCD 2025年第3期20-26,共7页
Cold-surge events can lead to temperature drops and strong winds,which then leads to upper-ocean cooling and deepening of the mixed-layer depth,as illustrated in previous studies.In this study,based on the temperature... Cold-surge events can lead to temperature drops and strong winds,which then leads to upper-ocean cooling and deepening of the mixed-layer depth,as illustrated in previous studies.In this study,based on the temperature drop of Shanwei meteorological station,two extreme cold surges and five weak cold invasions in the South China Sea are simulated using an ocean-atmosphere coupled model to investigate their different impacts on the upper-ocean temperature.The diffusion term contributes to the difference in temperature tendency of the upper 20 m,while the advection term contributes to the positive difference from 20 to 80 m of the offshore region and negative difference from 80 to 160 m.In addition,the significant differences are attributed primarily to the influence of the upper-ocean temperature gradient,which subsequently impacts the advection term and results in notable differences in temperature tendency at depths from 80 to 160 m. 展开更多
关键词 Cold surges Upper-ocean temperature tendency Air-sea coupled model
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Non-planar vibration characteristics and buckling behaviors of two fluid-conveying pipes coupled with an intermediate spring 认领 引用 被引量：2
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作者 Dali WANG Tianli JIANG +1 位作者 Huliang DAI Lin WANG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2025年第10期1829-1850,共22页
This study investigates the dynamical behavior of two parallel fluid-conveying pipes by developing a non-planar dynamical model of the two pipes coupled with an intermediate spring. A systematic analysis is conducted ... This study investigates the dynamical behavior of two parallel fluid-conveying pipes by developing a non-planar dynamical model of the two pipes coupled with an intermediate spring. A systematic analysis is conducted to evaluate the effects of spring parameters on the non-planar vibration characteristics and buckling behaviors of the coupled system. The nonlinear governing equations are derived with Hamilton's principle,subsequently discretized through Galerkin's method, and finally numerically solved by the Runge-Kutta algorithm. Based on the linearized equations, an eigenvalue analysis is performed to obtain the coupled frequencies, modal shapes, and critical flow velocities for buckling instability. Quantitative assessments further elucidate the effects of the spring position and stiffness coefficient on the coupled frequencies and critical flow velocities.Nonlinear dynamic analyses reveal the evolution of buckling patterns and bifurcation behaviors between the lateral displacements of the two pipes and the flow velocity. Numerical results indicate that the intermediate spring increases the susceptibility to buckling instability in the out-of-plane direction compared with the in-plane direction. Furthermore, synchronized lateral displacements emerge in both pipes when the flow velocity of one pipe exceeds the critical threshold. This work is expected to provide a theoretical foundation for the stability assessment and vibration analysis in coupled fluid-conveying pipe systems. 展开更多
关键词 coupled fluid-conveying pipe system intermediate spring non-planar vibration buckling behavior
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Expert consensus on orthodontic-associated alveolar ridge augmentation for adult patients 认领 引用 被引量：2
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作者 Runzhi Guo Xiaotong Li +24 位作者 Jianxia Hou Yiping Huang Bing Fang Hong He Zuolin Jin Fuhua Yan Lin Wang Yuxing Bai Wenjie Hu Lili Chen Jinlin Song Xianglong Han Fang Jin Jun Wang Min Hu Yang Cao Yuehua Liu Haiping Lu Bin Yan Yan Xu Wensheng Ma Yifan Lin Xiao Xu Li Xu Weiran Li 《International Journal of Oral Science》 SCIE CAS CSCD 2026年第2期208-217,共10页
Alveolar bone defects,including dehiscence and fenestration,are commonly encountered in adult patients seeking orthodontic treatment.These anatomical deficiencies increase the risk of periodontal complications and may... Alveolar bone defects,including dehiscence and fenestration,are commonly encountered in adult patients seeking orthodontic treatment.These anatomical deficiencies increase the risk of periodontal complications and may significantly compromise orthodontic tooth movement.Alveolar bone defects can also develop during orthodontic treatment,particularly in adult patients with narrow alveolar ridges requiring excessive tooth movement.Orthodontic-associated alveolar ridge augmentation(OARA)is an effective treatment approach that provides additional bone support and facilitates tooth movement,thereby reducing the incidence of periodontal complications and accelerating and broadening the scope of movement.At present,standardized diagnostic and treatment protocols for OARA in adult patients are lacking.This expert consensus aims to provide evidence-based recommendations for OARA in adult patients.A multidisciplinary panel of 27 experts conducted a Delphi-style process incorporating a targeted literature review and three voting rounds,achieving≥70%agreement.Twenty-nine consensus statements across seven clinical domains,including pre-OARA examination,indications,bone graft material selection,timing,surgical protocols,standard operating procedures and considerations,were established with recommendations graded according to adapted GRADE criteria.This report presents a structured clinical framework for OARA and identifies future research priorities. 展开更多
关键词 bone defects alveolar bone defectsincluding dehiscence periodontal complications narrow alveolar ridges alveolar bone defects orthodontic associated alveolar ridge augmentation anatomical deficiencies
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To Understand the Radiative Processes of Pulsars and Fast Radio Bursts with the FAST 认领 引用
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作者 Wei-Yang Wang Shunshun Cao +39 位作者 Zhipeng Huang Jiguang Lu Yunpeng Men Lingqi Meng Jiarui Niu Zhichen Pan Pengfei Wang Dejiang Zhou Yi Feng Jinlin Han Jinchen Jiang Bin Liu Rui Luo Hongguang Wang Shuangqiang Wang Tao Wang Zhengli Wang Heng Xu Jiangwei Xu Renxin Xu Yonghua Xu Yi Yan Zhen Yan Yukai Zhou Siyuan Chen Yinfeng Dai Mingyu Ge Zejun Jiang Kejia Lee Yujie Lian Kuo Liu Lei Qian Hao Tong Lin Wang Yujie Wang Zihao Xu Jumei Yao Dejiang Yin Li Zhang Weiwei Zhu 《Chinese Physics Letters》 SCIE EI CAS CSCD 2026年第5期431-460,共30页
The radiative mechanism of coherent radio emission has remained an enigma since the discovery of pulsars,even with the emergence of fast radio bursts(FRBs),which exhibit similarities to the single-pulse behavior of pu... The radiative mechanism of coherent radio emission has remained an enigma since the discovery of pulsars,even with the emergence of fast radio bursts(FRBs),which exhibit similarities to the single-pulse behavior of pulsars and have opened a new window for deciphering this long-standing mystery.Besides tremendous efforts in modeling,advanced facilities are essential for solving the problem.The authors review the observational breakthroughs made with the Five-hundred-meter Aperture Spherical Radio Telescope(FAST),which are providing pivotal insights into the underlying physics of pulsars and FRBs.This study offers a novel perspective in the era when pulsars meet FRBs,and further investigations are encouraged to utilize the high sensitivity of FAST. 展开更多
关键词 observational breakthroughs Five hundred meter aperture spherical radio telescope FAST coherent radio emission fast radio bursts frbs which fast radio bursts pulsars radiative mechanism
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Structural disorder-driven synthesis of C2+hydrocarbons via direct hydrogenation of amorphous carbon with continuous random atomic networks 认领 引用
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作者 Shaojie Wang Mingtao Li +10 位作者 Zhongyan Wu Saichao Cao Penghui Li Xiang Zhang Zhiwei Shen Hongkai Li Ke Yang Li Zhang Guoying Gao Lin Wang Yongjun Tian 《Matter and Radiation at Extremes》 SCIE EI CAS CSCD 2026年第1期93-102,共10页
Recent advances in geoscience have underscored the critical role of abiogenic processes in petroleum formation,especially the formation and polymerization of methane.However,whether a direct carbon-H2 reaction can ... Recent advances in geoscience have underscored the critical role of abiogenic processes in petroleum formation,especially the formation and polymerization of methane.However,whether a direct carbon-H2 reaction can produce C2+hydrocarbons(e.g.,ethane and propane)beyond methane remains an open question.Here,we demonstrate the direct synthesis of ethane and propane via reactions between amorphous carbon and H2 under upper mantle conditions(2-10 GPa and 800-1200℃).A systematic investigation reveals that increasing structural disorder in carbon precursors,from graphite to glassy carbon-Ⅱ and carbon black,enhances the production of C2-C3 hydrocarbons.Through integrated X-ray diffraction and reverse Monte Carlo simulations,we establish that the continuous random atomic network structures in amorphous carbon enable one-step synthesis of heavy hydrocarbons with H2.These models establish a direct link between atomic-scale carbon structures and the one-step synthesis of C2+ hydrocarbons under H2-rich,high-pressure,and high-temperature conditions—potentially revealing an efficient mechanism for the abiotic production of C2+ hydrocarbons in the upper mantle. 展开更多
关键词 systematic investigation abiogenic processes formation polymerization hydrogenation amorphous carbon ethane structural disorder propane
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Recent progress and perspectives in fusion welding of Mg-RE alloys:From weldability fundamentals to process-microstructure correlation 认领 引用
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作者 Xin Tong Qiman Wang +5 位作者 Guohua Wu Wenbing Zou Liang Zhang Lin Wang Yingxin Wang Wenjiang Ding 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2026年第1期68-95,共28页
Magnesium-rare earth(Mg-RE)alloys are pivotal for lightweight applications in aerospace and advanced engineering due to their high specific strength.However,manufacturing large-scale complex components via monolithic ... Magnesium-rare earth(Mg-RE)alloys are pivotal for lightweight applications in aerospace and advanced engineering due to their high specific strength.However,manufacturing large-scale complex components via monolithic casting is challenging owing to defects such as RE oxides and shrinkage porosity,making fusion welding essential for both defect repair and structural joining.This review comprehensively examines recent advances in fusion welding of Mg-RE alloys,with emphasis on the interplay between their unique physicochemical properties and welding metallurgy.Various fusion welding methods suitable for Mg-RE alloys are compared and analyzed.Detailed characterization of joint regions reveals how thermal gradients and cooling rates govern phase evolution,grain morphology,and defect formation.Moreover,welding parameters and heat treatment strategies are systematically discussed for the microstructural configuration,especially for the inherent conflicts between grain coarsening in fusion zone and eutectic dissolution in heat-affected zone.Future research directions are also outlined.By correlating Mg-RE alloy properties with fusion welding processes,this review provides practical insights for designing reliable welded structures in critical applications. 展开更多
关键词 Mg-RE alloys Fusion welding Weldability Welding heat treatment Microstructural regulation
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Chronic exposure to low-dose cadmium disrupts spermatogenesis in mice through ectoplasmic specialization damage 认领 引用
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作者 Yue Li Zi-Fa Li +4 位作者 Bo Qiu Kai Chen Tian-Lin Zhang Hai-Peng Wang Lin Wang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第6期632-643,共12页
Cadmium(Cd)is a ubiquitous environmental pollutant threatening ecosystem stability and public health.Cd is also a known male reproductive toxicant that disrupts the blood-testis barrier,thereby inhibiting the spermato... Cadmium(Cd)is a ubiquitous environmental pollutant threatening ecosystem stability and public health.Cd is also a known male reproductive toxicant that disrupts the blood-testis barrier,thereby inhibiting the spermatogenesis function.However,the mechanisms underlying Cd-inhibited spermatogenesis function remain largely unknown.Hereby,we established a mouse model exposed to environmentally relevant doses of Cd(1.45 and 7.25 mg Cd/(kg feed)through dietary supplementation for 24 weeks and conducted corresponding in vitro experiments to elucidate Cd-induced spermatogenesis dysfunction.Data first showed that chronic Cd exposure caused sperm quality decline and testicular damage.Ultrastructural observations further revealed the impairment of ectoplasmic specialization(ES)structure in Sertoli cells.Transcriptome analysis and subsequent verification experiments suggested that Cd-induced mixed lineage kinase domain-like protein(MLKL)activation and its resultant translocation to the endoplasmic reticulum(ER)triggered excessive ER stress.Finally,based on the correlation analysis,we identified that Cd-induced excessive ER stress resulted in ES disruption,leading to spermatogenesis dysfunction.In summary,this study reveals a new mechanism by which chronic environmental Cd exposure induces spermatogenesis dysfunction through MLKL-mediated ER stress,providing potential therapeutic targets for mitigating Cd-induced male reproductive toxicity. 展开更多
关键词 Cadmium Spermiogenesis Ectoplasmic specialization Mixed lineage kinase domain-like protein Endoplasmic Reticulum
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Self-supporting composite anodes with three-dimensional network by wood-derived hard carbon in rechargeable metallic magnesium batteries 认领 引用
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作者 Lin Wang Kai Sun +4 位作者 Zengyan Wei Wenshu Yang Qiang Zhang Huasong Gou Gaohui Wu 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2026年第5期225-235,共11页
Rechargeable metallic magnesium batteries(RMBs)are expected to be a potential replacement for lithium counterparts.Yet,exotic electrolyte components forming passing layers on magnesium(Mg)surfaces usually leads to ult... Rechargeable metallic magnesium batteries(RMBs)are expected to be a potential replacement for lithium counterparts.Yet,exotic electrolyte components forming passing layers on magnesium(Mg)surfaces usually leads to ultrahigh overpotential for reversible Mg chemistry.Here a novel self-supporting composite was constructed to address this issue by using chemically activated natural jujube woodderived hard carbons(a-JHCs)with a three-dimensional(3D)network like skeleton as the artificial Mg-ions(Mg2+)-conducting interphase,achieving selective Mg2+transport.Different from the traditional artificial solid-electrolyte interphase(SEI),the porous a-JHCs allows for 3D ion-conduction,thereby improving ion transport efficiency.Meanwhile,interfacial characteristics of a-JHCs have been demonstrated to suppress the intrusion of Mg deposits into micro-porous separators,allowing the Mg plating/stripping reaction beneath the interface.The artificial interface with low electronic conductivity significantly stabilizes the Mg electrode in conventional organic electrolytes.We show this proof-of-concept enables the reversible cycling of a Mg||V2O5full-cell in the water-containing,and also opens the door to electrolytes previously considered as non-compatible with Mg. 展开更多
关键词 Mg batteries Interface modification Hard carbon/Mg composites Reversible Mg chemistry Pressure infiltration
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Data-driven iterative calibration method for prior knowledge of earth-rockfilldam wetting model parameters 认领 引用
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作者 Shaolin Ding Jiajun Pan +4 位作者 Yanli Wang Lin Wang Han Xu Yiwei Lu Xudong Zhao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第2期1621-1632,共12页
Wetting deformation in earth-rockfill dams is a critical factor influencingdam safety.Although numerous mathematical models have been developed to describe this phenomenon,most of them rely on empirical formulations a... Wetting deformation in earth-rockfill dams is a critical factor influencingdam safety.Although numerous mathematical models have been developed to describe this phenomenon,most of them rely on empirical formulations and lack prior knowledge of model parameters,which is essential for Bayesian parameter inversion to enhance accuracy and reduce uncertainty.This study introduces a datadriven approach to establishing prior knowledge of earth-rockfill dams.Driving factors are utilized to determine the potential range of model parameters,and settlement changes within this range are calculated.The results are iteratively compared with actual monitoring data until the calculated range encompasses the observed data,thereby providing prior knowledge of the model parameters.The proposed method is applied to the right-bank earth-rockfilldam of Danjiangkou.Employing a Gibbs sample size of 30,000,the proposed method effectively calibrates the prior knowledge of the wetting model parameters,achieving a root mean square error(RMSE)of 5.18 mm for the settlement predictions.By comparison,the use of non-informative priors with sample sizes of 30,000 and 50,000 results in significantly larger RMSE values of 11.97 mm and 16.07 mm,respectively.Furthermore,the computational efficiencyof the proposed method is demonstrated by an inversion computation time of 902 s for 30,000 samples,which is notably shorter than the 1026 s and 1558 s required for noninformative priors with 30,000 and 50,000 samples,respectively.These findingsunderscore the superior performance of the proposed approach in terms of both prediction accuracy and computational efficiency.These results demonstrate that the proposed method not only improves the predictive accuracy but also enhances the computational efficiency,enabling optimal parameter identificationwith reduced computational effort.This approach provides a robust and efficientframework for advancing dam safety assessments. 展开更多
关键词 Earth-rockfilldam Wetting deformation Prior knowledge Data-driven Bayesian inversion
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Atmospheric new particle formation from sulfuric acid-amine nucleation in a rural area of the North China Plain 认领 引用
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作者 Yiliang Liu Yiqun Lu +6 位作者 Gan Yang Chuang Li Yuwei Wang Runlong Cai Lei Yao Yang Chen Lin Wang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第7期597-604,共8页
New particle formation(NPF)is a key source of atmospheric ultrafine particles.While previous studies have identified NPF pathways across various environments,its mechanisms in polluted rural areas remain poorly unders... New particle formation(NPF)is a key source of atmospheric ultrafine particles.While previous studies have identified NPF pathways across various environments,its mechanisms in polluted rural areas remain poorly understood.This study presents field observations from a polluted rural region in the North China Plain,revealing that sulfuric acid(SA)-dimethylamine(DMA)-H2O nucleation dominated the observed NPF events.This study quantitatively examined the initial formation of SA clusters under varying nucleation precursor concentrations and background particle concentrations.The observed SA dimer concentrations correlated well with the predictions of the SA-DMA-H2O nucleation mechanism.Decreased DMA concentration and elevated condensation sink(CS)suppressed SA dimer formation.We also introduced a diagnostic parameter—the ratio of SA dimers to the square of SA monomers,[(SA)2]/[(SA)1]2,to characterize the nucleation probability.Notably,strong NPF events tend to occur when this ratio exceeded 5×10–9cm3.These findings offer new insights into NPF dynamics in polluted rural environments,highlighting the complex interactions between multiple precursors and atmospheric conditions. 展开更多
关键词 New particle formation Sulfuric acid-dimethylamine nucleation Rural area North China Plain
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Numerical Simulation of the Welding Deformation of Marine Thin Plates Based on a Temperature Gradient-thermal Strain Method 认领 引用
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作者 Lin Wang Yugang Miao +3 位作者 Zhenjian Zhuo Chunxiang Lin Benshun Zhang Duanfeng Han 《哈尔滨工程大学学报（英文版）》 CSCD 2026年第1期122-135,共14页
Marine thin plates are susceptible to welding deformation owing to their low structural stiffness.Therefore,the efficient and accurate prediction of welding deformation is essential for improving welding quality.The t... Marine thin plates are susceptible to welding deformation owing to their low structural stiffness.Therefore,the efficient and accurate prediction of welding deformation is essential for improving welding quality.The traditional thermal elastic-plastic finite element method(TEP-FEM)can accurately predict welding deformation.However,its efficiency is low because of the complex nonlinear transient computation,making it difficult to meet the needs of rapid engineering evaluation.To address this challenge,this study proposes an efficient prediction method for welding deformation in marine thin plate butt welds.This method is based on the coupled temperature gradient-thermal strain method(TG-TSM)that integrates inherent strain theory with a shell element finite element model.The proposed method first extracts the distribution pattern and characteristic value of welding-induced inherent strain through TEP-FEM analysis.This strain is then converted into the equivalent thermal load applied to the shell element model for rapid computation.The proposed method-particularly,the gradual temperature gradient-thermal strain method(GTG-TSM)-achieved improved computational efficiency and consistent precision.Furthermore,the proposed method required much less computation time than the traditional TEP-FEM.Thus,this study lays the foundation for future prediction of welding deformation in more complex marine thin plates. 展开更多
关键词 Marine thin plate Welding deformation Numerical simulation Temperature gradient-thermal strain method Shell element
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Alkali-cyano dual-tailored g-C3N4/BiOCl S-scheme heterojunctions for highly efficient visible-light-driven H2O2photosynthesis in pure water 认领 引用
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作者 Ziyi Liao Lan Jiang +3 位作者 Yang Yang Lin Wang Weiyou Yang Huilin Hou 《Chinese Journal of Catalysis》 SCIE EI CAS CSCD 2026年第4期143-161,共19页
Efficient and sustainable photocatalytic hydrogen peroxide(H2O2)synthesis is crucial due to its role as an eco-friendly oxidant and the limitations of conventional industrial methods.Graphitic carbon nitride(g-C... Efficient and sustainable photocatalytic hydrogen peroxide(H2O2)synthesis is crucial due to its role as an eco-friendly oxidant and the limitations of conventional industrial methods.Graphitic carbon nitride(g-C3N4)is a promising photocatalyst but suffers from inefficient charge separation and limited visible light absorption.This study introduces a dual-modified g-C3N4,incorporating Na+/K+ions and cyano groups,coupled with ultrathin BiOCl nanosheets to form an S-scheme heterojunction(CN-NH-NaK/BiOCl).The modification enhances the electronic structure,visible light absorption,and charge separation.The CN-NH-NaK/BiOCl photocatalyst achieved an outstanding H2O2production rate of 33.15 mmol·g-1·h-1under visible light(λ≥400 nm),outperforming pristine g-C3N4(118-fold)and BiOCl(83-fold),and surpassing all previously reported g-C3N4-and BiOCl-based photocatalysts.Even in pure water,the production rate reached 5.18 mmol·g-1·h-1,exceeding that of most previously reported catalysts.Comprehensive characterization revealed an efficient S-scheme charge transfer mechanism,enabling selective 2e-oxygen reduction reaction(94.06%selectivity)and water oxidation.The heterojunction demonstrated excellent stability,reusability,and enhanced degradation of tetracycline hydrochloride.This work provides a promising strategy for advanced S-scheme photocatalysts in sustainable H2O2production and environmental remediation. 展开更多
关键词 S-scheme heterojunction H2O2photosynthesis g-C3N4 BiOCl
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Post-stroke electroacupuncture promotes cerebrovascular repair in the peri‑infarct cortex of ischemic stroke mice 认领 引用
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作者 Yun-shi LIN Rui ZHANG +6 位作者 Ji-qin XIANG Xin LI An-xin ZHANG Xiao-rong TANG Lin WANG Neng-gui XU Rong-rong TAO 《World Journal of Acupuncture-Moxibustion》 CAS CSCD 2026年第2期197-207,共11页
Objective Cerebrovascular repair plays a crucial role in promoting post-stroke neurological recovery.However,effective strategies to enhance cerebrovascular repair and the underlying mechanisms remain elusive.Here,we ... Objective Cerebrovascular repair plays a crucial role in promoting post-stroke neurological recovery.However,effective strategies to enhance cerebrovascular repair and the underlying mechanisms remain elusive.Here,we investigated whether post-stroke electroacupuncture(EA)treatment could promote cerebrovascular repair and thereby improve neurological function,as well as the potential mechanisms involved.Methods Eight-week-old male C57BL/6 J mice were subjected to photothrombosis-induced brain ischemia.Following successful model induction,the mice were randomly assigned to the model group,the EA continuous wave group(EA[Co]),and the EA dense-sparse wave group(EA[SD]),with 10 animals in each group.A sham-operated group(n=10)served as the control.The EA groups received a 4-week EA intervention targeting the acupoints“Neiguan(PC6)”and“Sanyinjiao(SP6)”.EA was administered five times per week with bilateral stimulation,and the affected side was connected to the EA device.The EA(SD)group received stimulation at 2/10 Hz,whereas the EA(Co)group received continuous wave stimulation at 2 Hz or 50 Hz;both were delivered at an intensity of 1 mA for 20 min per session.Twenty-four hours after photothrombosis induction,laser speckle contrast imaging and 2,3,5-triphenyltetrazolium chloride staining were performed to confirm model establishment and cerebral ischemic injury.Neurological function was evaluated using behavioral tests,including the adhesive removal test,hanging wire test,and elevated plus maze test.Immunofluorescence staining was performed to assess neuronal viability,cerebral microvascular structure,endothelial cell proliferation,and vascular repair markers in the peri‑infarct cortex.Results Significant reductions in cerebral blood perfusion(P0.05).(2)In the wire hanging test,the model group exhibited significantly lower muscle strength scores than the sham group(P0.05).(4)Immunofluorescence staining showed a significantly reduced density of Nissl+/NeuN+double-labeled neurons in the peri‑infarct regions of the model group compared with the control group(P0.05).(5)In terms of cerebrovascular structure,the model group exhibited significantly reduced vascular volume,microvascular branching density,and microvascular length in the peri‑infarct regions compared with the control group(all P0.05).Following EA treatment,this density was significantly increased compared with the model group(P0.05).(7)Compared with the control group,the model group exhibited significant reductions in lectin-labeled glycocalyx in vessels and basement membrane protein collagen Ⅳ expression(all P0.05).Conclusion This study demonstrates that EA promotes cerebrovascular repair and neurological recovery after ischemic stroke by enhancing microvascular remodeling,stimulating endothelial proliferation,and restoring basement membrane and glycocalyx integrity.EA(Co)is more effective than EA(SD)in repairing vascular structure.These findings provide mechanistic evidence that EA is a promising therapeutic approach for post-stroke rehabilitation and suggest that waveform optimization may enhance its clinical efficacy. 展开更多
关键词 Ischemic stroke Electroacupuncture Cerebral microvessel Neurological dysfunction
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A Multi-Model Ensemble Approach for Constructing Subseasonal Extreme Forecast Index of Temperature 认领 引用
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作者 Hong-Li REN Yujun WANG +4 位作者 Li GAO Lin WANG Minghong Liu Yinghan SANG Jieru MA 《Journal of Meteorological Research》 SCIE CSCD 2026年第4期1151-1162,共12页
Current subseasonal forecasting of extreme temperature in China faces challenges due to relatively low capability of the subseasonal-to-seasonal(S2S)models.Benefiting from ensemble forecasting,the extreme forecast ind... Current subseasonal forecasting of extreme temperature in China faces challenges due to relatively low capability of the subseasonal-to-seasonal(S2S)models.Benefiting from ensemble forecasting,the extreme forecast index(EFI)is an effective approach to tackling the challenge;however,it usually requires abundant ensemble members(i.e.,dynamic models),while individual S2S models usually have a limited sample of members that constrain their performance in constructing EFI.To address this issue,this study proposes a novel subseasonal EFI approach for temperature utilizing the S2S multi-model ensemble(MME)to provide a much larger ensemble size.This approach,applied to both a bias-corrected MME(MME-C)and a direct MME(MME-D),is evaluated for high temperature scenarios in comparison with the ECMWF single model forecasts.The results show that MME-C,by removing the drifted climatology of individual model and replacing it with observed climatology,can maximally use the unbiased large-sample ensemble information to decently construct EFI.For verification of subseasonal forecast of extremely high temperatures over China,both MME approaches for the EFI construction outperform the ECMWF single model,e.g.,threat score(TS)of MME-C can reach 0.52 for 27-day forecasts,and MME-C achieves overall higher skills than MME-D.The decreased skills with lead time exhibit variations across different regions and both of the MME approaches show higher temporal correlation coefficient(TCC)skills in the northern regions such as Northwest and Northeast China and achieve smaller errors across the entire China.Using larger-sample MME information,the MME-C approach proves to be an effective tool for improving subseasonal early warnings of extreme high-temperature risks. 展开更多
关键词 extreme forecast index(EFI) multi-model ensemble(MME) subseasonal-to-seasonal(S2S) high temperature bias correction
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