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U-shape association between serum chloride and in-hospi-tal mortality in patients with coronary heart disease and diabetes mellitus in intensive care units:Data from the MIMIC-Ⅳdatabase 认领 引用
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作者 LIU Ting-ting ZHANG Lu +4 位作者 MA Kai-ying HU Chun-jie LV Ping ZHANG Rui-gui YANG Liu 《South China Journal of Cardiology》 CAS 2026年第1期32-44,共13页
Background Chloride,the most abundant anion in extracellular fluid,plays a crucial role in maintaining ho-meostasis.Previous studies have shown that hypochloremia independently predicts adverse outcomes in various cli... Background Chloride,the most abundant anion in extracellular fluid,plays a crucial role in maintaining ho-meostasis.Previous studies have shown that hypochloremia independently predicts adverse outcomes in various clinical settings.However,the association between serum chloride levels and in-hospital mortality in intensive care unit(ICU)patients with coronary heart disease(CHD)and diabetes mellitus(DM)remains unclear.This study aimed to determine whether initial serum chloride is associated with in-hospital mortality in this population.Meth-ods We enrolled 4343 ICU patients with CHD and DM and categorized them into three groups based on artificial-ly defined cutoffs of serum chloride levels:low(≤100 mmol/L),middle(100-110 mmol/L),and high(>110 mmol/L).The relationship between admission serum chloride and in-hospital mortality was first analyzed using restricted cubic spline regression(RCS)to evaluate nonlinearity.Threshold and saturation effects were examined to confirm the findings.Multivariable logistic regression was used to assess the association between serum chloride and in-hos-pital mortality.Results A U-shaped relationship was observed between serum chloride and in-hospital mortality,with the lowest risk at a threshold of 107 mmol/L.Below and above this threshold,the odds ratios(ORs)were 0.95(95%CI:0.93-0.97,P110 mmol/L)groups had ORs for in-hospital mortality of 1.83(95%CI:1.42-2.36,P<0.0001)and 2.46(95%CI:1.43-4.23,P=0.0011),respectively.Both low and high serum chloride levels were associated with increased in-hospital mortality risk.Conclusions This study identified a U-shaped association between serum chloride levels and in-hospital mortality in ICU patients with CHD and DM.Independent risk factors for increased mortality in this study constitut-ed both low and high serum chloride concentrations. 展开更多
关键词 Serum chloride Coronary heart disease Diabetes mellitus In-hospital mortality
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白裤瑶族服饰图案在文创产品中的创新应用 认领 引用 被引量：3
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作者 马凯莹 徐丽君 徐云 《湖南包装》 2023年第3期138-142,共5页
文章在索绪尔符号学理论下,以白裤瑶族服饰为基点,运用转译与形状文法,提炼图案元素、挖掘符号语言,并依据形状文法的推演规则进行元素的解构和重组、再设计与表现,利用形态学序贯减薄运算进行主骨架线的设计,最后结合形式美法则,将创... 文章在索绪尔符号学理论下,以白裤瑶族服饰为基点,运用转译与形状文法,提炼图案元素、挖掘符号语言,并依据形状文法的推演规则进行元素的解构和重组、再设计与表现,利用形态学序贯减薄运算进行主骨架线的设计,最后结合形式美法则,将创新设计的图案运用于文创产品设计中。白裤瑶族服饰图案的再运用可以促进服饰图案的传承与创新,拓宽白裤瑶民族文化传播的宣传方式,让白裤瑶民族符号元语言在新时代语境下焕发新生。 展开更多
关键词 索绪尔符号学 转译 形状文法 文创产品 白裤瑶
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