Implementation of genomic tools is desirable to increase the efficiency of apple breeding.Recently,the multi-environment apple reference population(apple REFPOP)proved useful for rediscovering loci,estimating genomic ...Implementation of genomic tools is desirable to increase the efficiency of apple breeding.Recently,the multi-environment apple reference population(apple REFPOP)proved useful for rediscovering loci,estimating genomic predictive ability,and studying genotype by environment interactions(G×E).So far,only two phenological traits were investigated using the apple REFPOP,although the population may be valuable when dissecting genetic architecture and reporting predictive abilities for additional key traits in apple breeding.Here we show contrasting genetic architecture and genomic predictive abilities for 30 quantitative traits across up to six European locations using the apple REFPOP.A total of 59 stable and 277 location-specific associations were found using GWAS,69.2%of which are novel when compared with 41 reviewed publications.Average genomic predictive abilities of 0.18-0.88 were estimated using main-effect univariate,main-effect multivariate,multi-environment univariate,and multi-environment multivariate models.The G×E accounted for up to 24% of the phenotypic variability.This most comprehensive genomic study in apple in terms of traitenvironment combinations provided knowledge of trait biology and predictionmodels that can be readily applied for marker-assisted or genomic selection,thus facilitating increased breeding efficiency.展开更多
基金partially supported by the Horizon 2020 Framework Program of the European Union under grant agreement No 817970(project INVITE:“Innovations in plant variety testing in Europe to foster the introduction of new varieties better adapted to varying biotic and abiotic conditions and to more sustainable crop management practices”)partially supported by the project RIS3CAT(COTPAFRUIT3CAT)financed by the European Regional Development Fund through the FEDER frame of Catalonia 2014-2020+2 种基金by the CERCA Program from Generalitat de Catalunyafinancial support from the Spanish Ministry of Economy and Competitiveness through the“Severo Ochoa Programme for Centres of Excellence in R&D”2016-2019(SEV-20150533)and 2020-2023(CEX2019-000902-S)supported by“DON CARLOS ANTONIO LOPEZ”Abroad Postgraduate Scholarship Program,BECAL-Paraguay.
摘要Implementation of genomic tools is desirable to increase the efficiency of apple breeding.Recently,the multi-environment apple reference population(apple REFPOP)proved useful for rediscovering loci,estimating genomic predictive ability,and studying genotype by environment interactions(G×E).So far,only two phenological traits were investigated using the apple REFPOP,although the population may be valuable when dissecting genetic architecture and reporting predictive abilities for additional key traits in apple breeding.Here we show contrasting genetic architecture and genomic predictive abilities for 30 quantitative traits across up to six European locations using the apple REFPOP.A total of 59 stable and 277 location-specific associations were found using GWAS,69.2%of which are novel when compared with 41 reviewed publications.Average genomic predictive abilities of 0.18-0.88 were estimated using main-effect univariate,main-effect multivariate,multi-environment univariate,and multi-environment multivariate models.The G×E accounted for up to 24% of the phenotypic variability.This most comprehensive genomic study in apple in terms of traitenvironment combinations provided knowledge of trait biology and predictionmodels that can be readily applied for marker-assisted or genomic selection,thus facilitating increased breeding efficiency.