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The Present and Future of Aging-on-a-Chip 认领 引用
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作者 Xuan Mei Xingchen Liu +5 位作者 Zaiyi Yang Nigel Foo Peter Wang Ming Shao Dean Ho Yu Shrike Zhang 《Engineering》 SCIE EI CSCD 2026年第7期19-23,共5页
1.Introduction。Aging is a systemic and progressive challenge of significant societal,medical,and scientific urgency.With global populations aging rapidly,age-related diseases,such as neurodegeneration and cardiovascu... 1.Introduction。Aging is a systemic and progressive challenge of significant societal,medical,and scientific urgency.With global populations aging rapidly,age-related diseases,such as neurodegeneration and cardiovascular dysfunction,are accelerating,underscoring the urgent need to understand the mechanisms of aging and develop effective interventions.The trending organ-on-a-chip(OoC)technology offers a powerful solution by recapitulating organ-or tissue-level functions.However,the applications of OoC in aging research remain limited,since most current systems are confined to models that simulate endpoint phenotypes rather than the dynamic evolution of aging itself. 展开更多
关键词 age related diseases organ chip develop effective interventionsthe aging cardiovascular dysfunction understand mechanisms aging neurodegeneration systemic challenge
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