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Designing dual-functional lighting via Eu3+-activated MF2(M2+=Ca2+,Sr2+and Ba2+)red-emitting nanoparticles 认领 引用 被引量：2
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作者 Duoyin Chen Xuanyu Ge +2 位作者 Laihui Luo Weiping Li Peng Du 《Nano Materials Science》 EI CAS CSCD 2025年第4期511-521,共11页
Developing high efficient and stable red-emitting phosphors is very important in the areas of white lightingemitting diode(white-LED)and plant growth.Herein,series of Eu3+-activated MF2(M2+=Ca2+,Sr2+,Ba... Developing high efficient and stable red-emitting phosphors is very important in the areas of white lightingemitting diode(white-LED)and plant growth.Herein,series of Eu3+-activated MF2(M2+=Ca2+,Sr2+,Ba2+)red-emitting nanoparticles(NPs)were synthesized at room temperature.Excited at 394 nm,these resulting NPs can emit dazzling red emissions and their fluorescence intensities are sensitive to both dopant content and host compound.Moreover,it is found that the studied samples have admirable thermal stability,high quantum efficiencies and color purities,which can be regulated via changing host material.To assess the possible application of final products,three different white-LEDs were packaged by using Eu3+-activated MF2(M2+=Ca2+,Sr2+,Ba2+)red-emitting NPs.Clearly,these manufactured white-LEDs can produce glaring warm white with satisfied electroluminescence behaviors,i.e.low correlated color temperature(80).Furthermore,via using the designed NPs,three red-emitting LEDs were also fabricated so as to identify their applications in plant growth.Our findings imply that Eu3+-activated MF2(M2+=Ca2+,Sr2+,Ba2+)NPs are well-suited for dual-functional lighting as red-emitting converters in the realms of white-LED and artificial plant growth LED. 展开更多
关键词 Luminescent materials Nanoparticles Plant growth White-LED
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Dual phase equal-atomic NbTaTiZr high-entropy alloy with ultra-fine grain and excellent mechanical properties fabricated by spark plasma sintering 认领 引用 被引量：3
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作者 Tao Xiang Zeyun Cai +3 位作者 Peng Du Kun Li Zongwei Zhang Guoqiang Xie 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2021年第31期150-158,共9页
Super-high strength NbTaTiZr high-entropy alloys(NbTaTiZr HEAs)have been successfully fabricated by the mechanical alloying(MA)with spark plasma sintering(SPS)technology,which is 2-fold compared with that of NbTaTiZr ... Super-high strength NbTaTiZr high-entropy alloys(NbTaTiZr HEAs)have been successfully fabricated by the mechanical alloying(MA)with spark plasma sintering(SPS)technology,which is 2-fold compared with that of NbTaTiZr HEAs prepared by vacuum arc melting(VAM).After the SPS process,the bulk NbTaTiZr alloy samples are provided with dual-phase body-centered cubic(BCC)structure and nanoscale grain size about 500 nm that is obviously smaller than that of NbTaTiZr HEA fabricated by VAM.When the sintering temperature is 800℃,the compressive fracture strength is the highest reaching at 2511±78 MPa.When the sintering temperature is 1000℃,the fracture strain is the highest reaching at 12.8%,and compressive fracture strength and yield strength also reach at 2274±91 MPa and 2172±47 MPa,respectively.The excellent mechanical properties of bulk NbTaTiZr alloy samples are attributed to the merits of MA and SPS,and the collaboration effect of ultra-fine grains strengthening,solid solution strengthening and interstitial solid solution strengthening. 展开更多
关键词 NbTaTiZr high-entropy alloys Mechanical alloying Ultra-fine grain Spark plasma sintering Mechanical properties Corrosion behavior
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Fabrication of porous TiZrNbTa high-entropy alloys/Ti composite with high strength and low Young’s modulus using a novel MgO space holder 认领 引用 被引量：1
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作者 Tao Xiang Jie Chen +3 位作者 Weizong Bao Shuyan Zhong Peng Du Guoqiang Xie 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2023年第36期59-73,共15页
Stress shielding is caused by the mismatch of stiffness between bone and implant materials,which may give rise to bone resorption and loosening,thereby causing implantation failure.There is a huge gap between Young’s... Stress shielding is caused by the mismatch of stiffness between bone and implant materials,which may give rise to bone resorption and loosening,thereby causing implantation failure.There is a huge gap between Young’s modulus of human bone and low Young’s modulusβTi alloys.A porous structure design can achieve the target of low Young’s modulus,and thus achieve the matching between human bone and implant materials.However,a suitable space holder(SH)that can be applied at high temperatures and sintering pressure has not been reported.In this study,the TiZrNbTa/Ti titanium matrix composite(TMC)with high strength and large ductility was used as scaffold materials and combined the SH technique with the spark plasma sintering(SPS)technique to obtain a porous structure.A novel space holder,i.e.,MgO particles was adopted,which can withstand high-temperature sintering accompanied by a sintering pressure.The porous TiZrNbTa/Ti with 40 vol.%MgO added exhibits a maximum strength of 345.9±10.4 MPa and Young’s modulus of 24.72±0.20 GPa,respectively.It possesses higher strength compared with human bone and matches Young’s modulus of human bone,which exhibits great potential for clinical application. 展开更多
关键词 TiZrNbTa/Ti titanium matrix composite MgO space holder Low Young’s modulus High strength
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Progress on Wastewater-based Epidemiology in China:Implementation Challenges and Opportunities in Public Health 认领 引用
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作者 Qiuda Zheng Xialu Lin +9 位作者 Yingsheng He Zhe Wang Peng Du Xiqing Li Yuan Ren Degao Wang Luhong Wen Zeyang Zhao Jianfa Gao Phong KThai 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2025年第11期1354-1358,共5页
Wastewater-based epidemiology has emerged as a transformative surveillance tool for estimating substance consumption and monitoring disease prevalence,particularly during the COVID-19 pandemic.It enables the populatio... Wastewater-based epidemiology has emerged as a transformative surveillance tool for estimating substance consumption and monitoring disease prevalence,particularly during the COVID-19 pandemic.It enables the population-level monitoring of illicit drug use,pathogen prevalence,and environmental pollutant exposure.In this perspective,we summarize the key challenges specific to the Chinese context:(1)Sampling inconsistencies,necessitating standardized 24-hour composite protocols with high-frequency autosamplers(≤15 min/event)to improve the representativeness of samples. 展开更多
关键词 standardized protocols estimating substance consumption sampling inconsistencies wastewater based epidemiology challenges China high frequency autosamplers
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Validation of the youth version of the Alimetry®Gut‑Brain Wellbeing Survey:a mental health scale for young people with chronic gastroduodenal symptoms 认领 引用
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作者 Mikaela Law Gayl Humphrey +9 位作者 Isabella Pickering Gabriel Schamberg Chris Varghese Peng Du Charlotte Daker Hayat Mousa Armen Gharibans Greg O’Grady Christopher N.Andrews Stefan Calder 《World Journal of Pediatrics》 SCIE CSCD 2026年第4期465-476,共12页
Background This research outlines the development and validation of the Alimetry®Gut-Brain Wellbeing Survey-Youth Version(AGBW-Y),a novel tool for assessing mental health in young people with chronic gastroduoden... Background This research outlines the development and validation of the Alimetry®Gut-Brain Wellbeing Survey-Youth Version(AGBW-Y),a novel tool for assessing mental health in young people with chronic gastroduodenal symptoms aged 12–17 years.Methods In Phase 1,global feedback was gathered from 19 pediatric clinicians in the gastroenterology feld and 33 young people over multiple rounds to make the adult AGBW Survey more age-appropriate for young people.In Phase 2,rigorous psychometric testing was conducted in a sample of 128 patients aged 12–17 years with chronic gastroduodenal symptoms,using an anonymous survey.Results Based on the feedback from Phase 1,an interdisciplinary team of experts improved the survey’s language and usability for young people to enhance the scale’s clarity,acceptability,and face and content validity.The fnal AGBW-Y comprises a patient preface,10 closed-ended questions,and an open-ended question.It assesses general mental health,alongside subscales of depression,stress,and anxiety.Phase 2 demonstrated excellent psychometric properties of the scale,including high internal consistency reliability(α=0.91 for the total scale;α=0.75–0.85 for subscales)and strong convergent,divergent,and concurrent validity with large efect sizes.Conclusions The AGBW-Y is a brief,reliable,and valid tool to assess mental health in young people aged 12–17 years with chronic gastroduodenal symptoms.This novel scale was developed through rigorous co-design with clinicians and young people,ensuring it is contextually relevant and clinically impactful.The AGBW-Y complements existing physiological assessments,enabling evaluations that can guide psychological referrals,support multidisciplinary care,and evaluate treatment outcomes. 展开更多
关键词 Adolescent Brain–gut axis Gastrointestinal diseases Mental health Psychometrics
MoS2 Nanosheets/3D Graphene on a Porous Nickel Tube as an Efficient Electrocatalyst for Hydrogen Evolution 认领 引用
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作者 Peng Du Ouna Yi +4 位作者 Xingyu Ai Yufei Wu Meiling Zhu Yong Zhang Xilong Wang 《Carbon and Hydrogen》 SCIE CAS CSCD 2025年第4期528-537,共10页
Designing an efficient electrocatalyst for hydrogen evolution reaction(HER)is rather essential for the field of electrocatalytic hydrogen production.We here report a three-dimensional(3D)graphene nanowire grown on our... Designing an efficient electrocatalyst for hydrogen evolution reaction(HER)is rather essential for the field of electrocatalytic hydrogen production.We here report a three-dimensional(3D)graphene nanowire grown on our self-made porous nickel tube prepared by a microwave plasma enhanced chemical vapor deposition(MPCVD)method.Then,the MoS2 nanosheets are in situ grown on graphene in a vertically stacked manner through a simple hydrothermal synthesis method.It is found that these vertical graphene nanosheets can be used as an effective support to anchor MoS2 nanosheets stably and evenly on its surface.As a result,the prepared catalyst exhibits excellent HER electrocatalytic activity,which is attributed to plentiful edge active sites provided by the vertical MoS2 nanosheets and the efficient electron transport pathway provided by graphene on a matrix with good conductivity.In addition,the outwardly extending nanowire-like structure of the catalyst increases its surface area,as well as reduces the steric hindrance between active sites and the electrolyte. 展开更多
关键词 edge active sites electrocatalytic activity graphene HER hydrogen production
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Targeting 50% air-pollution mortality reduction by 2040 requires transformative,health-oriented precision emission reduction 认领 引用
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作者 Peng Du Hang Du +2 位作者 Yuanyuan Liu Shuxiao Wang Tiantian Li 《The Innovation》 EI 2026年第3期7-8,共2页
In May 2025,the 78 th World Health Assembly adopted a global roadmap to address the health effects of air pollution.Within this framework,the World Health Organization(WHO)proposed an ambitious target of reducing mort... In May 2025,the 78 th World Health Assembly adopted a global roadmap to address the health effects of air pollution.Within this framework,the World Health Organization(WHO)proposed an ambitious target of reducing mortality from anthropogenic air pollution by 50% by 2040 relative to 2015.This sets a significantly higher benchmark for global air quality actions. 展开更多
关键词 air quality actions health effects WHO World Health Assembly air pollution precision emission reduction mortality reduction global roadmap
Enhanced measurement precision with continuous interrogation during dynamical decoupling 认领 引用
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作者 张军 杜鹏 +3 位作者 敬雷 徐鹏 尤力 张文献 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期88-94,共7页
Dynamical decoupling(DD)is normally ineffective when applied to DC measurement.In its straightforward implementation,DD nulls out DC signal as well while suppressing noise.This work proposes a phase relay method that ... Dynamical decoupling(DD)is normally ineffective when applied to DC measurement.In its straightforward implementation,DD nulls out DC signal as well while suppressing noise.This work proposes a phase relay method that is capable of continuously interrogating the DC signal over many DD cycles.We illustrate its efficacy when applied to the measurement of a weak DC magnetic field with an atomic spinor Bose-Einstein condensate.Sensitivities approaching standard quantum limit or Heisenberg limit are potentially realizable for a coherent spin state or a squeezed spin state of 10000 atoms,respectively,while ambient laboratory level noise is suppressed by DD.Our work offers a practical approach to mitigate the limitations of DD to DC measurement and would find other applications for resorting coherence in quantum sensing and quantum information processing research. 展开更多
关键词 quantum sensing continuous interrogation quantum magnetometer dynamical decoupling Heisenberg limit
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Radiomics for the detection of microvascular invasion in hepatocellular carcinoma 认领 引用 被引量：45
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作者 Kun Lv Xin Cao +3 位作者 Peng Du Jun-Yan Fu Dao-Ying Geng Jun Zhang 《World Journal of Gastroenterology》 SCIE CAS 2022年第20期2176-2183,共8页
Hepatocellular carcinoma(HCC)is the most common primary liver cancer,accounting for about 90%of liver cancer cases.It is currently the fifth most common cancer in the world and the third leading cause of cancer-relate... Hepatocellular carcinoma(HCC)is the most common primary liver cancer,accounting for about 90%of liver cancer cases.It is currently the fifth most common cancer in the world and the third leading cause of cancer-related mortality.Moreover,recurrence of HCC is common.Microvascular invasion(MVI)is a major factor associated with recurrence in postoperative HCC.It is difficult to evaluate MVI using traditional imaging modalities.Currently,MVI is assessed primarily through pathological and immunohistochemical analyses of postoperative tissue samples.Needle biopsy is the primary method used to confirm MVI diagnosis before surgery.As the puncture specimens represent just a small part of the tumor,and given the heterogeneity of HCC,biopsy samples may yield false-negative results.Radiomics,an emerging,powerful,and non-invasive tool based on various imaging modalities,such as computed tomography,magnetic resonance imaging,ultrasound,and positron emission tomography,can predict the HCC-MVI status preoperatively by delineating the tumor and/or the regions at a certain distance from the surface of the tumor to extract the image features.Although positive results have been reported for radiomics,its drawbacks have limited its clinical translation.This article reviews the application of radiomics,based on various imaging modalities,in preoperative evaluation of HCC-MVI and explores future research directions that facilitate its clinical translation. 展开更多
关键词 Microvascular invasion Hepatocellular carcinoma Radiomics Texture analysis Diagnostic imaging Liver
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Data release of the LAMOST pilot survey 认领 引用 被引量：57
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作者 A-Li Luo Hao-Tong Zhang +80 位作者 Yong-Heng Zhao Gang Zhao Xiang-Qun Cui Guo-Ping Li Yao-Quan Chu Jian-Rong Shi Gang Wang Jian-Nan Zhang Zhong-Rui Bai Xiao-Yan Chen Feng-Fei Wang Yan-Xin Guo Jian-Jun Chen Bing Du Xiao Kong Ya-Juan Lei Yin-Bi Li Yi-Han Song Yue Wu Yan-Xia Zhang Xin-Lin Zhou Fang Zuo Peng Du Lin He Wen Hou Yi-Qiao Dong Jian Li Guang-Wei Li Shuang Li Jing Song Yuan Tian Meng-Xin Wang Yong-Hui Hou Zhi-Ying Huo Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Lei Jia Fang-Hua Jiang Xiang Jiang Zi-Bo Jiang Ge Jin Ai-Hua Li Qi Li Yin-Dun Mao Zheng-Hong Tang Qing-Sheng Tao Liang-Ping Tu Da-Qing Wang Dan Wang Jian-Ping Wang Lei Wang Shou-Guan Wang Shu-Qing Wang Ya-Nan Wang You Wang Yue-Fei Wang Ming-Zhi Wei Xiang-Xiang Xue Xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu Yan Xu De-Hua Yang Shi-Hai Yang Zheng-Qiu Yao Yong Yu Hui Yuan Chao Zhai En-Peng Zhang Jing Zhang Li-Ping Zhang WeiZhang Yong Zhang Zhen-Chao Zhang Ming Zhao Fang Zhou Yong-Tian Zhu Jie Zhu Si-Cheng Zou 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2012年第9期1243-1246,共4页
This paper describes the data release of the LAMOST pilot survey,which includes data reduction,calibration,spectral analysis,data products and data access.The accuracy of the released data and the information about th... This paper describes the data release of the LAMOST pilot survey,which includes data reduction,calibration,spectral analysis,data products and data access.The accuracy of the released data and the information about the FITS headers of spectra are also introduced.The released data set includes 319000 spectra and a catalog of these objects. 展开更多
关键词 techniques spectroscopic survey—data reduction—data release
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Development of a static test apparatus for evaluating the performance of three PM2.5 separators commonly used in China 认领 引用 被引量：10
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作者 Peng Du Jianguo Liu +8 位作者 Huaqiao Gui Jiaoshi Zhang Tongzhu Yu Jie Wang Yin Cheng Yihuai Lu Yawei Yao Qiang Fu ChihChieh Chen 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2020年第1期238-249,共12页
PM2.5 separator directly affects the accuracy of PM2.5 sampling.The specification testing and evaluation for PM2.5 separator is particularly important,especially under China’s wide variation of terrain and climate.In... PM2.5 separator directly affects the accuracy of PM2.5 sampling.The specification testing and evaluation for PM2.5 separator is particularly important,especially under China’s wide variation of terrain and climate.In this study,first a static test apparatus based on polydisperse aerosol was established and calibrated to evaluate the performance of the PM2.5 separators.A uniform mixing chamber was developed to make particles mix completely.The aerosol concentration relative standard deviations of three test points at the same horizontal chamber position were less than 0.57%,and the particle size distribution obeyed logarithmic normal distribution with an R2 of 0.996.The flow rate deviation between the measurement and the set point flow rate agreed to within±1.0%in the range of-40 to 50℃.Secondly,the separation,flow and loading characteristics of three cyclone separators(VSCC-A,SCC-A and SCC112)were evaluated using this system.The results showed that the 50%cutoff sizes(D50)of the three cyclones were 2.48,2.47 and 2.44μm when worked at the manufacturer’s recommended flow rates,respectively.The geometric standard deviation(GSD)of the capture efficiency of VSCCA was 1.23,showed a slightly sharper than SCC-A(GSD=1.27),while the SCC112 did not meet the relevant indicator(GSD=1.2±0.1)with a GSD=1.44.The flow rate and loading test had a great effect on D50,while the GSD remained almost the same as before.In addition,the maintenance frequency under different air pollution conditions of the cyclones was summarized according to the loading test. 展开更多
关键词 PM2.5 separator Performance assessment Separation characteristics Flow characteristics Loading test
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Methylation of PTCH1a gene in a subset of gastric cancers 认领 引用 被引量：6
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作者 Peng Du Hai-Rong Ye +7 位作者 Jun Gao Wei Chen Zhong-Chuan Wang Hong-Hua Jiang Ji Xu Ji-We Zhang Jian-Cheng Zhang Long Cui 《World Journal of Gastroenterology》 SCIE CAS 2009年第30期3799-3806,共8页
AIM： To establish if PTCHla transcriptional regulation region （TRR） is methylated in gastric cancer and its influence in gastric tumorigenesis.METHODS： The CpG islands in PTCHla TRR were analyzed by Methyl Primer ... AIM： To establish if PTCHla transcriptional regulation region （TRR） is methylated in gastric cancer and its influence in gastric tumorigenesis.METHODS： The CpG islands in PTCHla TRR were analyzed by Methyl Primer Express v1.0 software. The region from -643 to -355 bp （the transcription initiation site of PTCHla was designated as 0） that contained 19 CpG sites was chosen for bisulfitesequencing PCR （BSP） and methylation-specific PCR （MSP） detection. The gastric cancer cell line AGS was treated with 5-aza-2′-deoxycytidine （5-Aza-dC; 1 μmol/L） for 3 d. Alterations in PTCHla TRR methylation in treated AGS cells was measured through BSP clone sequences, and their PTCH1 expression was measured by quantitative RT-PCR. The cell cycle and apoptosis were observed with flow cytometry through propidium iodide （PI） staining or annexin V/PI double staining. The prevalence of PTCHla TRR methylation was investigated in 170 gastric cancer tissue samples and the adjacent normal tissues by MSP. The correlation of PTCH1a TRR methylation with PTCH1 expression or with patients＇ clinical features was analyzed.RESULTS： Methylation of PTCHla TRR was observed in AGS ceils and a subset of gastric cancer tissues （32%, 55/170）, while no methylation amplification products were observed in any normal tissues by MSP. The methylation of PTCH1α TRR was correlated negatively with PTCH1 expression （Spearman＇s r = -0.380, P = 0.000）. However, methylation of PTCHla TRR was not related to the gastric cancer patients＇ clinical features, such as sex, age of onset, clinical stage, lymph node metastasis or histological grade. The methylation of PTCHla TRR in AGS cells was almost converted to non-methylation after 5-Aza-dC treatment, which increased PTCH1 expression （5.3 ± 2.5 times; n = 3） and apoptosis rate （3.0 ± 0.26 times; P 〈 0.05; n = 3）.CONCLUSION： Methylation of PTCH1α TRR is present in a subset of gastric cancers and correlated negatively with PTCH1 expression. This may be an early event in gastric tumorigenesis and a new treatment target. 展开更多
关键词 Carcinogenesis Methylation Hedgehogsignaling pathway Methylation PTCH1 Stomachneoplasms
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Helium extraction from natural gas using DD3R zeolite membranes 认领 引用 被引量：6
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作者 Ping Zhang Chao Gong +5 位作者 Tao Zhou Peng Du Jieyu Song Mengyang Shi Xuerui Wang Xuehong Gu 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2022年第9期122-129,共8页
Helium(He)is commercially produced from natural gas by low-temperature condensation.The process is energy extensive because of the extremely low He concentration(<0.3%)and the operation at cryogenic temperature.Her... Helium(He)is commercially produced from natural gas by low-temperature condensation.The process is energy extensive because of the extremely low He concentration(<0.3%)and the operation at cryogenic temperature.Herein we demonstrated DD3R zeolite membrane was efficient to extract He from natural gas at atmosphere temperature.The membrane performance was evaluated in terms of temperature,pressure and molar fractions.The overall membrane performance was dominated by the diffusivity selectivity.The single He permeance and ideal He/CH4 selectivity were 5.8×10-9mol·m-2·s-1·Pa-1and 79 under a feed pressure of 1.3 MPa.Even though He concentration was as low as 0.22%,the He permeance and He/CH4 mixture selectivity were 3.0×10-9mol·m-2·s-1·Pa-1and 44 at 0.7 MPa.During the longterm operation(~130 h)the membrane performance was stable even the feed mixture containing3.6%ethane as contaminations.The results approved the feasibility of DD3R zeolite membranes for He extraction from natural gas. 展开更多
关键词 He extraction Zeolite Membranes He/CH4separation Natural gas
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Androgen downregulation of miR-760 promotes prostate cancer cell growth by regulating IL6 认领 引用 被引量：5
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作者 Shuo Wang Yong Yang +2 位作者 Yu-Dong Cao Xing-Xing Tang Peng Du 《Asian Journal of Andrology》 SCIE CAS CSCD 2021年第1期85-90,共6页
Prostate cancer(PCa)is one of the most common malignancies in Western countries.Studies have shown that androgen contributes to the progression of PCa,but how androgen promotes PCa remains largely unknown.Here,we demo... Prostate cancer(PCa)is one of the most common malignancies in Western countries.Studies have shown that androgen contributes to the progression of PCa,but how androgen promotes PCa remains largely unknown.Here,we demonstrated that androgen suppressed the expression of miR-760 depending on the interaction between androgen and androgen receptor(AR).miR-760 was downregulated in prostate cancer tissues compared with normal tissues.Functional experiments showed that miR-760 downregulation promoted the proliferation and growth of LNCaP and 22rv1 cells.In contrast,miR-760 ectopic expression inhibited the proliferation of LNCaP and 22 rv1 cells.DNA synthesis was suppressed by miR-760.Mechanistically,miR-760 bound to the 3 fUTR of interleukin 6(IL6).A mutation in the binding site disrupted their interaction.In addition,silencing of IL6 suppressed the proliferation of LNCaP and 22 rv1 cells.IL6 was upregulated in PCa tissues.Our study reveals that androgen downregulates miR-760 to promote the growth of PCa cells by regulating IL6. 展开更多
关键词 androgen interleukin 6 miR-760 prostate cancer
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Phase-tunable equiatomic and non-equiatomic Ti-Zr-Nb-Tahigh-entropy alloys with ultrahigh strength for metallic biomaterials 认领 引用 被引量：4
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作者 Tao Xiang Peng Du +4 位作者 Zeyun Cai Kun Li Weizong Bao Xinxin Yang Guoqiang Xie 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2022年第22期196-206,共11页
The contradiction between the strength and ductility of metallic materials is a major scientific problemthat has been researched for a long time. Dual-phase equiatomic and non-equiatomic Ti-Zr-Nb-Ta highentropy alloys... The contradiction between the strength and ductility of metallic materials is a major scientific problemthat has been researched for a long time. Dual-phase equiatomic and non-equiatomic Ti-Zr-Nb-Ta highentropy alloys (HEAs) with super-high strength and excellent ductility have been successfully developedvia mechanical alloying (MA) combined with spark plasma sintering (SPS) technology. This is adjustedby altering the atomic ratios of the different phases. X-ray diffraction (XRD) and transmission electronmicroscopy (TEM) were performed to confirm the dual-phase microstructure. After the SPS process, theaverage grain size of the aforementioned equiatomic Ti25Zr25Nb25Ta25 HEAs (134 ± 50 nm) evaluated byelectron back-scattering diffraction (EBSD) is smaller than that of the Ti-Zr-Nb-Ta HEAs (150 μm), whichwere fabricated using arc melting. According to the Hall-Petch formula, the grain boundary strengthening contribution in the Ti-Zr-Nb-Ta system is 33-fold higher than those fabricated using the arc-meltingprocess. When the alloy phase comprises the equivalent dual-phase, equiatomic Ti25Zr25Nb25Ta25 HEAshave good comprehensive performance compared to non-equiatomic Ti-Zr-Nb-Ta HEAs prepared usingthe same process. The yield strength of equiatomic Ti25Zr25Nb25Ta25 HEAs (2212 ± 38 MPa) is two-foldhigher than that of Ti-Zr-Nb-Ta HEAs (1100 ± 90 MPa) fabricated via arc melting. This can be attributed tothe ultra-fine grain size. Notably, the equiatomic Ti25Zr25Nb25Ta25 HEAs possess approximately the samebiocompatibility as commercial pure Ti (CP-Ti), indicating that the equiatomic Ti25Zr25Nb25Ta25 HEAs areprovided with a possibility as an advanced biomaterial for the applications of the medical field. 展开更多
关键词 Equiatomic Nb25Ta25Ti25Zr25HEAs Ultra-fine grain Phase-tunable Mechanical properties Biocompatibility
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Identification of long-range transport pathways and potential sources of PM2.5 and PM10 in Beijing from 2014 to 2015 认领 引用 被引量：29
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作者 Deping Li Jianguo Liu +7 位作者 Jiaoshi Zhang Huaqiao Gui Peng Du Tongzhu Yu Jie Wang Yihuai Lu Wenqing Liu Yin Cheng 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2017年第6期214-229,共16页
Trajectory clustering, potential source contribution function （PSCF） and concentration-weighted trajectory （CWT） methods were applied to investigate the transport pathways and identify potential sources of PM2.s a... Trajectory clustering, potential source contribution function （PSCF） and concentration-weighted trajectory （CWT） methods were applied to investigate the transport pathways and identify potential sources of PM2.s and PMIo in different seasons from June 2014 to May 2015 in Beijing. The cluster analyses showed that Beijing was affected by trajectories from the south and southeast in summer and autumn. In winter and spring, Beijing was not only affected by the trajectories from the south and southeast, but was also affected by trajectories from the north and northwest. In addition, the analyses of the pressure profile of backward trajectories showed that backward trajectories, which have important influence on Beijing, were mainly distributed above 970 hPa in summer and autumn and below 950 hPa in spring and winter. This indicates that PM2.s and PMIo were strongly affected by the near surface air masses in summer and autumn and by high altitude air masses in winter and spring. Results of PSCF and CV/T analyses showed that the largest potential source areas were identified in spring, followed by winter and autumn, then summer. In addition, potential source regions of PMIo were similar to those of PM2.5. There were a clear seasonal and spatial variation of the potential source areas of Beijing and the airflow in the horizontal and vertical directions. Therefore, more effective regional emission reduction measures in Beijing＇s surrounding provinces should be implemented to reduce emissions of regional sources in different seasons. 展开更多
关键词 PM2.5 PM40 Cluster analyses PSCFCWT Beijing
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Mechanical properties and corrosion resistance of powder metallurgical Mg-Zn-Ca/Fe bulk metal glass composites for biomedical application 认领 引用 被引量：3
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作者 Kun Li Luxin Liang +5 位作者 Peng Du Zeyun Cai Tao Xiang Hiroyasu Kanetaka Hong Wu Guoqiang Xie 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2022年第8期73-83,共11页
Magnesium(Mg)alloys can be regarded as the most promising biodegradable implant materials for orthopedic and stent applications due to their good biocompatibility and low Young’s modulus which is near to that of natu... Magnesium(Mg)alloys can be regarded as the most promising biodegradable implant materials for orthopedic and stent applications due to their good biocompatibility and low Young’s modulus which is near to that of natural bone.However,its applicability is hindered because it exhibits a high corrosion rate in the physiological environments.In this work,we fabricated Mg66Zn30Ca4/Fe bulk metallic glass composites via spark plasma sintering(SPS).We studied the influence of different contents of Fe on the properties of the composites.The results indicated that Fe was uniformly distributed on the surface of Mg66Zn30Ca4 metallic glass(MG)as a second phase,which led to an improvement in the corrosion resistance and mechanical strength.The standard potential of Mg66Zn30Ca4/Fe bulk metallic glass(BMG)composites increased as compared to Mg66Zn30Ca4,while their mechanical strength improved from 355 MPa to 616 MPa.Furthermore,cytotoxicity was investigated via the CCK-8 assay and calcein-AM staining,which revealed that the extraction mediums diluted 6 times(EM×6)of the Mg66Zn30Ca4 and Mg66Zn30Ca4/Fe did not cause cell toxicity on day 3 and 5,while the EM×6 of the Mg66Zn30Ca4 showed cytotoxicity on day 1,3 and 5.Thus,Mg66Zn30Ca4/Fe BMG composites exhibit significant potential for fabricating implants with good mechanical strength and corrosion resistance. 展开更多
关键词 Mg66Zn30Ca4/Fe bulk metallic glass composites Spark plasma sintering Corrosion behaviour Mechanical strength
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PINPOINT SOURCE LOCALIZATION FOR OCULAR NONSELECTIVE ATTENTION WITH COMBINATION OF ERP AND fNIRI MEASUREMENTS 认领 引用 被引量：3
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作者 TING LI LI LI +2 位作者 PENG DU QINGMING LUO HUI GONG 《Journal of Innovative Optical Health Sciences》 SCIE EI 2008年第2期195-206,共12页
Compared with event-related potential(ERP)which is widely used in psychology research,functional near-infrared imaging(fNIRI)is a new technique providing hemodynamic information related to brain activity,except for el... Compared with event-related potential(ERP)which is widely used in psychology research,functional near-infrared imaging(fNIRI)is a new technique providing hemodynamic information related to brain activity,except for electrophysiological signals.Here,we use both these techniques to study ocular attention.We conducted a series of experiments with a classic paradigm of ocular nonselective attention,and monitored responses with fNIRI and ERP respectively.The results showed that fNIRI measured brain activations in the left prefrontal lobe,while ERPs showed activation in frontal lobe.More importantly,only with the combination measurements of fNIRI and ERP,we were then able to find the pinpoint source of ocular nonselective attention,which is in the left and upper corner in Brodmann area 10.These results demonstrated that fNIRI is a reliable technique in psychology,and the combination of fNIRI and ERP can be promising to reveal more information in the research of brain mechanism. 展开更多
关键词 Functional near-infrared imaging(fNIRI) event-related potential(ERP) ocular nonselective attention hemoglobin
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Pseudo-dynamic testing of a fabricated composite frame with steel plate shear walls 认领 引用 被引量：3
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作者 Zheng-gang CAO Peng DU +1 位作者 Feng FAN Zhe-ming CHEN 《Journal of Zhejiang University-SCIENCE A》 SCIE EI CAS CSCD 2017年第6期454-466,共13页
A pseudo-dynamic testing program was generated on a fabricated composite frame with steel plate shear walls （SPSWs） to study its seismic perlbrmance. The specimen was a three-storey single-bay frame, which was compo... A pseudo-dynamic testing program was generated on a fabricated composite frame with steel plate shear walls （SPSWs） to study its seismic perlbrmance. The specimen was a three-storey single-bay frame, which was composed of H- section steel columns and composite beams, and was assembled by bolted height-adjustable steel beam-to-column connections （BHA connections）. Beam-only-connected SPSWs were selected as lateral load resisting members. The specimen was subjected to four ground motions of progressively increasing intensity. The results showed that： （1） beam-only-connected S PSWs provided sufficient lateral load resistance, lateral stiffness, and energy dissipation capacity to the fabricated frame via the tension ficld action developed in their infill panels; （2） the fabricated frame, assembled by BHA connections, exhibited substantial redundancy and good ductility; （3） an undesirable failure mode of the fabricated frame, in huge earthquakes, included severe cracking in composite beams and block shear failure in SPSWs＇ connections; （4） the inter-storey shear force distribution determined by ASCE/SE1 7-10 was verified with experimental data. 展开更多
关键词 Fabricated frame Composite beam Steel plate shear walls Pseudo-dynamic test
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Nicotine protects against DSS colitis through regulating microRNA-124 and STAT3 认领 引用 被引量：2
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作者 Zhen QIN Jing-jing WAN +6 位作者 Yang SUN Ting-yu WU Peng-yuan WANG Peng DU Ding-feng SU Yi-li YANG Xia LIU 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2018年第4期264-264,共1页
OBJECTIVE Although it is generally believed that nicotine accounts for the beneficial effect of smoking on ulcerative colitis,the underlying mechanisms remain not well understood.Our previous finding that nicotine inh... OBJECTIVE Although it is generally believed that nicotine accounts for the beneficial effect of smoking on ulcerative colitis,the underlying mechanisms remain not well understood.Our previous finding that nicotine inhibits inflammatory responses through inducing miRNA-124 prompted us to ask whether the miRNA is involved in the protective action of nicotine on UC.METHODS MiR-124 expres.sion in colon tissues and cells was determined by q-PCR and in situ hybridization.The effect of miR-124 on protective role of nicotine in ulcerative colitis was evaluated in DSS-treated mice and IL-6-treated Caco-2 colon epithelial cells.Expression of p-STAT3/STAT3 was detected by immunohistochemistry and Western-blot analysis.RESULTS miR-124 expression is upregulated in colon tissues from UC patients and DSS-induced colitis mice.Nicotine treatment further elevated miR-124 level in lympho.cytes isolated from human ulcerative colonic mucosa and ulcerative colon tissues from DSS mice,both in infiltrated lymphocytes and epithelial cells.Administration of nicotine also reduced weight loss,improved DAI and decreased HE score in DSS-induced colitis mice.Moreover,knockdown of miR-124 in vivo significantly diminished the beneficial effect of nicotine on murine colitis,and in vitro on IL-6-treated Caco-2 colon epithelial cells.Further analysis indicated that nicotine inhibited STAT3 activation in vivo and in IL-6-treated Caco-2 colon epithelial cells and Jurkat human T lymphocytes,in which miR-124 knockdown led to increased activation of STAT3.Blocking STAT3 activity alone is beneficial for DSS colitis and also abolished nicotine′s protective effect in this model.CONCLUSION These data indicated that nicotine exerts its protective action in UC through inducing miR-124 and its effect on STAT3,and suggest that the miR-124/STAT3 system is a potential target for the therapeutic intervention of UC. 展开更多
关键词 尼古丁 结肠炎 治疗方法 临床分析
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