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Effects of Qixuekang oral liquid in leukopenia during chemotherapy and radiotherapy in patients with malignant tumors:A randomized,double-blind,placebo-controlled,multicenter study 认领 引用
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作者 Yafang Cai Peng Xue +7 位作者 Xinyu Hu Huijie Wang Liping Liu Yi Li Jun Xiao Changgang Sun Yufeng Wang Shijie Zhu 《Journal of Traditional Chinese Medical Sciences》 CAS CSCD 2026年第2期267-275,共9页
Objective:To assess the efficacy and safety of Qixuekang oral liquid in the treatment of leukopenia during chemotherapy and radiotherapy.Methods:This randomized,double-blind,placebo-controlled,multicenter clinical tri... Objective:To assess the efficacy and safety of Qixuekang oral liquid in the treatment of leukopenia during chemotherapy and radiotherapy.Methods:This randomized,double-blind,placebo-controlled,multicenter clinical trial was conducted between July 2018 and May 2021.A total of 234 patients with malignant tumors were enrolled from 12 medical centers.They were randomly assigned to receive either Qixuekang oral liquid or placebo in addition to standard chemotherapy and radiotherapy,with a treatment duration≤42 days.The primary outcome was defined as the change in peripheral white blood cell(WBC)count,determined by routine laboratory hematology tests,from baseline(D-7 to D0)to Day 42(±2 days)of dosing(D42).Results:In the full analysis set comprising 227 patients(113 and 114 in the experimental and control groups,respectively),a significant reduction in WBC count was observed after treatment(P.05).Conclusion:Qixuekang oral liquid may exert a therapeutic effect in mitigating leukopenia induced by chemotherapy and radiotherapy,while exhibiting favorable safety profiles. 展开更多
关键词 Qixuekang oral liquid Chemotherapy Radiotherapy Leukopenia Malignant tumors White blood cell count Randomized controlled trial
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Current trends in advanced imaging modalities for the early diagnosis of Alzheimer's disease 认领 引用
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作者 Xingli Zhang Peng Xue 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第3期154-170,共17页
Alzheimer's disease(AD)is a progressive neurodegenerative disorder characterized by complex pathological features such as amyloid-β plaques and tau tangles.Early and accurate diagnosis is crucial for effective in... Alzheimer's disease(AD)is a progressive neurodegenerative disorder characterized by complex pathological features such as amyloid-β plaques and tau tangles.Early and accurate diagnosis is crucial for effective intervention,yet remains challenging.This review focuses on current and emerging imaging modalities used in AD detection,including positron emission tomography,single-photon emission computed tomography,magnetic resonance imaging(MRI),fluorescence imaging,photoacoustic imaging,and mass spectrometry imaging,with an emphasis on their mechanisms,advantages,and limitations.Special attention is given to the integration of nanotechnology with imaging platforms,highlighting how nanomaterials enhance diagnostic specificity,sensitivity,stability and therapeutic potential.The review also explores recent advances in multimodal imaging,artificial intelligence-assisted diagnostics,and future directions toward personalized and other non-invasive strategies for early AD diagnosis. 展开更多
关键词 Alzheimer’s disease Imaging technologies Nanotechnology Diagnosis Theranostics
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Generalized Ellipsometry Measurement based on Variable Angle Driven by Single Motor 认领 引用
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作者 Peng Xue Quanlong Yang +1 位作者 Rui Zhang Zhibin Wang 《Instrumentation》 2026年第2期59-65,共7页
With the advancement of microelectronics,semiconductors,and nanotechnology,thin-film materials have found extensive applications in electronic and optical components.The thin-film thickness serves as a critical parame... With the advancement of microelectronics,semiconductors,and nanotechnology,thin-film materials have found extensive applications in electronic and optical components.The thin-film thickness serves as a critical parameter affecting the performance and reliability of such components.For rapid,non-destructive,and precise thickness measurements,generalized ellipsometers have attracted considerable research.However,commercially available ellipsometers typically require two motors to realize the variable angle(one to control the polarization state generator/analyzer,and another to rotate the sample stage).This conventional design suffers from complex structure,high cost and difficulty in optical path calibration after angle variation.To address these limitations,a novel variable angle structure driven by single motor is proposed in this paper,in which the polarization state generator is fixed and the polarization state analyzer and the sample stage are driven simultaneously using single motor to realize the variable angle.Using the developed system,standard thin-film samples of Au,Ag,and Cu,each with a nominal thickness of 50 nm,were tested.The results indicated that the thicknesses of the three samples fell within the range of 50±2 nm.Furthermore,the system exhibited minimal measurement error at an incident angle of 70°.These findings demonstrate that the proposed ellipsometry system with variable angle driven by single motor offers higher integration,simpler operation,and lower cost compared to traditional dual-motor designs. 展开更多
关键词 generalized ellipsometry thin-film measurement single-motor drive
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Enhanced strength-ductility-toughness synergy of friction stir-welded ultrahigh-strength medium-Mn steel joints via post-weld annealing 认领 引用
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作者 Leping Wang Zhiwei Wang +7 位作者 Peng Xue Hao Zhang Zhen Zhang Fengchao Liu Lihui Wu Dingrui Ni Bolv Xiao Zongyi Ma 《Metals Advances》 SCIE EI CAS CSCD 2026年第5期44-56,共13页
Ultrahigh-strength medium-Mn steels are one of the promising third-generation advanced high-strength steels with strength-ductility-toughness synergy.However,it has been a challenge to preserve the superior mechanical... Ultrahigh-strength medium-Mn steels are one of the promising third-generation advanced high-strength steels with strength-ductility-toughness synergy.However,it has been a challenge to preserve the superior mechanical properties of ultrahigh-strength medium-Mn steels after fusion welding due to the high heat input-induced transformation of metastable microstructures.In this work,ultrahigh-strength medium-Mn steel plates with 1 GPa strength were joined by a solid-state welding technique—friction stir welding.Defect-free joints were fabricated under a specific parameter window.Transformation of austenite to quenched martensite with high hardness occurred in the nugget zones(NZs).All the as-welded joints exhibited equal strengths but significant losses in ductility compared to the base metal(BM).Moreover,the impact energies of the NZs were greatly reduced to less than 6 J,which induced premature failures of the joints.After post-weld annealing at an intercritical temperature,reverse transformation of austenite occurred in the NZs,producing a composited structure of ultrafine ferrite,martensite,and austenite.The impact energies of the annealed NZs increased to over 23 J,which was much higher than the 2.2 J measured in the as-welded counterparts.The hardness of the NZs was significantly reduced,enabling sizeable tensile elongations of the joints close to that of the BM.Consequently,enhanced strength-ductility-toughness synergy of ultrahigh-strength medium-Mn steel joints was achieved by post-weld annealing.This work demonstrates a viable method to fabricate ultrahigh-strength medium-Mn steel joints with high performance. 展开更多
关键词 Ultrahigh-strength medium-Mn steel Friction stir welding Intercritical annealing Microstructure evolution Strength-ductility-toughness synergy
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Full‑Photolithographic High‑Density Skin‑Like Transistor Arrays for All‑Organic Active‑Matrix Displays 认领 引用
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作者 Peng Xue Juntong Li +15 位作者 Xiaoli Zhao Yanping Ni Hongyan Yu Xianghui Liu Bowen Xiang Yao Fu Junru Zhang Baoying Sun Pengbo Xi Xiang Song Yijun Shi Guodong Zhao Mingxin Zhang Yanhong Tong Qingxin Tang Yichun Liu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2026年第8期395-409,共15页
Organic thin-film transistors(OTFTs)are widely recognized as promising building blocks for nextgeneration flexible and wearable electronics.However,scalable fabrication of high-density OTFT arrays for activematrix app... Organic thin-film transistors(OTFTs)are widely recognized as promising building blocks for nextgeneration flexible and wearable electronics.However,scalable fabrication of high-density OTFT arrays for activematrix applications remains highly challenging,primarily due to the incompatibility of conventional photolithography with organic semiconductors.Here,we report an all-photolithographic strategy that enables the scalable fabrication of flexible OTFT arrays with both high device density and superior charge transport characteristics.By combining synergistic interfacial modulation and dual-protection photolithography strategy of organic semiconductors,we successfully fabricated transistor arrays exhibiting an average mobility above 1.0 cm2 V−1 s−1 and on/off ratios of~105.This scalable method further enables an integration density of 6.25×104 cm−2,which is one of the highest densities reported to date for full-photolithographic OTFT active-matrix arrays.Moreover,we demonstrate seamless integration of OTFT active-matrix arrays with organic light-emitting diodes(OLEDs),yielding all-organic active-matrix OLED(AMOLED)arrays.These devices exhibit stable electroluminescence,ultralight weight(~24.3 g m−2),excellent flexibility,and skinlike display functionality with reliable pixel-level addressing.This work establishes a universal and scalable route toward high-density organic electronic systems,opening new opportunities for flexible displays,electronic skin,and next-generation wearable technologies. 展开更多
关键词 Active-Matrix Organic thin-film transistors Photolithography Organic light-emitting diodes
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Panax quinquefolius polysaccharides enhance the therapeutic efficacy of rare ginsenosides in mice infected with Listeria monocytogenes by inhibiting NF-κB and regulating macrophage polarization 认领 引用
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作者 Yi He Hao Lu +7 位作者 Tai-Feng Cao Hai-Zhen Liu Ruo-Yu Zhang Ning Tang Cheng-Cheng Han Jin-Jin Jing Wen-Jing Jia Peng Xue 《Traditional Medicine Research》 2026年第7期12-24,共13页
Background:This study aims to investigate the therapeutic potential of rare ginsenosides(HTS)derived from Panax quinquefolius stem-leaf saponins(AGS)on LM infected mice,and to explore its synergistic anti LM mechanism... Background:This study aims to investigate the therapeutic potential of rare ginsenosides(HTS)derived from Panax quinquefolius stem-leaf saponins(AGS)on LM infected mice,and to explore its synergistic anti LM mechanism with its Panax quinquefolius polysaccharides(AGP).The mechanism by which AGP enhances the efficacy of rare ginsenosides is also explored through macrophage polarization.Methods:HTS was separated from total ginseng saponins;AGP was characterized using UV-Vis,IR spectroscopy,and monosaccharide composition analysis.An in vivo mouse model of LM infection was established,with penicillin and negative control groups.Efficacy was assessed by survival rate,organ bacterial load,ALT levels,inflammatory cytokines,and histopathology.An in vitro model used LTA-induced RAW264.7 macrophages,with NF-κB,CD68,and CD163 mRNA levels detected via qRT-PCR and immunofluorescence.Results:High-dose HTS(20 mg/kg)alone resulted in only 16.7%survival and significant liver injury.In contrast,HTS(5 mg/kg)and AGP(5 mg/kg)co-administration significantly increased survival to 66.7%,reduced hepatic bacterial load and ALT,downregulated IFN-γand IL-1β,and alleviated liver pathology.In vitro,HTS+AGP reduced LTA-induced cytotoxicity,suppressed NF-κB activation,and decreased secretion of NO,TNF-α,and IL-6.It also reversed the LTA-induced M1 macrophage bias by downregulating CD68 and upregulating CD163,increasing the CD163+/CD68+ ratio.Conclusion:AGP can enhance the therapeutic effect of HTS on LM infection by alleviating excessive inflammatory response in infected mice,regulating macrophage polarization balance,and providing experimental basis and theoretical support for the development of new anti-resistant bacterial strategies based on natural active ingredients and the rational application of rare saponins. 展开更多
关键词 Listeria monocytogenes rare ginsenosides Panax quinquefolius polysaccharide macrophage polarization
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Ultrahigh strength heat-resistant Al-Fe-V-Si-Sc alloy fabricated by laser powder bed fusion 认领 引用 被引量：2
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作者 Xu Tang Hao Zhang +7 位作者 Peng Xue Lihui Wu Junfan Zhang Lifeng Zhang Fengchao Liu Dingrui Ni Bolv Xiao Zongyi Ma 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2025年第36期299-306,共8页
Additive manufacturing provides an opportunity to efficiently produce the structure-performance integrated forming of aluminum alloy components,which has long been a primary objective in the aerospace and automobile i... Additive manufacturing provides an opportunity to efficiently produce the structure-performance integrated forming of aluminum alloy components,which has long been a primary objective in the aerospace and automobile industries.However,achieving nearly fully dense additive manufacturing of high-strength aluminum alloys remains a major challenge because of their high cracking sensitivity.In this study,an Al-Fe-V-Si-Sc alloy was designed and prepared by laser powder bed fusion(LPBF).The extremely high cooling rate and thermal gradient during the LPBF process facilitate the formation of a unique hierarchical heterostructure.The amorphous/crystal composite structure,located at the molten pool center,along with various nanoscale precipitates present at the molten pool boundary,can provide strengthening effects to this alloy,thereby conferring ultrahigh strength on the alloy at both room temperature and elevated temperatures.These findings offer valuable insights into the design of additively manufactured aluminum alloys,holding great promise for the advancement of aerospace components. 展开更多
关键词 Laser powder bed fusion Al-Fe-V-Si-Sc alloy Microstructure Mechanical properties
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Effect of Ga doping on glass-forming ability and mechanical properties of CuZrAlY metallic glass composites 认领 引用 被引量：1
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作者 Peng XUE Kun QIAN +5 位作者 Xiao-bing LI Bo CHEN Lei SHU Meng-shu ZHANG Jun-jie HAO Kui LIU 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2025年第5期1560-1569,共10页
The influence of Ga doping on the structure and mechanical properties of B2-CuZr phase reinforced larger-size CuZrAlY metallic glass composites was investigated by experiments and simulations.The result showed that as... The influence of Ga doping on the structure and mechanical properties of B2-CuZr phase reinforced larger-size CuZrAlY metallic glass composites was investigated by experiments and simulations.The result showed that as Ga content increased,the glass-forming ability of CuZrAlY metallic glass composites was gradually enhanced.Section morphology and thermal analysis indicated that Ga doping induced the decreased content of the crystals and the enlargement of the super-cooled liquid region,and increased activation energy for crystallization.Ga also stabilized the B2-CuZr phase.Characterization of the microstructure and mechanical test results suggested that the B19'-CuZr phase disappeared in the as-cast samples after adding Ga,and the martensitic transformation of the B2-CuZr phase was hindered when Ga content increased.The evolution mechanism of mechanical behaviors of the CuZr-based metallic glass composites during Ga doping was clarified by first-principles calculation.The results would be beneficial to the development and application of large-size CuZr-based metallic glass composites. 展开更多
关键词 metallic glass composite alloying thermal properties mechanical properties density functional theory
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Effect of Post Weld Heat Treatment on Residual Stress and Mechanical Properties of 106 mm Thick TC4 Titanium Alloy Electron Beam Welded Joints 认领 引用
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作者 Yunlu Jiang Lihui Wu +5 位作者 Dingrui Ni Hongbo Zhao Xu Han Peng Xue Bolv Xiao Zongyi Ma 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2025年第7期1083-1094,共12页
This study analyzed through-thickness distribution of residual stress in a 106 mm ultra-thick TC4 titanium alloy electron beam welded(EBW)joint after post weld heat treatment(PWHT)using X-ray diffraction(XRD)and deep-... This study analyzed through-thickness distribution of residual stress in a 106 mm ultra-thick TC4 titanium alloy electron beam welded(EBW)joint after post weld heat treatment(PWHT)using X-ray diffraction(XRD)and deep-hole drilling(DHD)methods,and investigated the microstructure and mechanical properties.During the PWHT at 600℃,a phase transformation(β→α)occurred in the EBW joint and affected the residual stress distribution and mechanical properties.The surface residual stress was mainly compressive stress,while the internal residual stress was mainly tensile stress in the welded joint.For the as-welded joint,the absolute value of surface residual stress was higher than the absolute value of internal residual stress.After PWHT,the residual stress in the treated joint was substantially reduced compared to the as-welded joint,particularly the surface stress,which relieved from−425 to−90 MPa.However,the residual stress relief effect had minimal positive impact on the internal region at 600℃.PWHT resulted in a shift of the joint fracture location from the fusion zone(FZ)to the base metal(BM),and therefore exerted no noticeable effect on the joint strength,but increased the joint elongation significantly.This study provides valuable insights into the regulation of residual stress distribution of ultra-thick titanium alloy plates. 展开更多
关键词 Titanium alloy Electron beam welding Residual stress Post weld heat treatment Mechanical property
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Fabrication of welded hybrid joints of aluminum alloys and polymer composites with significantly enhanced long-term reliability 认领 引用
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作者 Chunyang Jiang Fengchao Liu +8 位作者 Lihui Wu Ying Kan Xianjun Pei Hao Zhang Zhen Zhang Peng Xue Dingrui Ni Bolv Xiao Zongyi Ma 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2025年第12期3029-3042,共14页
The effect of thermal degradation on the welded hybrid joints of metal and polymer composites is insufficient,which seriously inhibits the engineering applications of the joints.In this study,robust hybrid joints of m... The effect of thermal degradation on the welded hybrid joints of metal and polymer composites is insufficient,which seriously inhibits the engineering applications of the joints.In this study,robust hybrid joints of metal and polymer composites were fabricated by the combination of friction lap welding(FLW)and laser surface treatment for investigating the effect of accelerated aging on the joint properties.Results showed that the FLW hybrid joints without laser surface treatment exhibited 91%reduction in the tensile shear force(TSF)after 7 days of accelerated aging tests.In contrast,the FLW hybrid joints with suitable laser surface treatment exhibited only 26%reduction in TSF even after 35 days of accelerated aging tests.Fractures of the tensile specimens occurred across the composite plates rather than along the joint interface.The enhanced reliability of the hybrid joints was mainly attributed to(1)the formation of micro-mechanical interlocking between the polymer composites and aluminum alloy plate,and(2)the modification of the stress distribution along the joint interface. 展开更多
关键词 dissimilar material welding fiber reinforced polymers friction lap welding friction stir welding hybrid structures
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Effects of Zr addition on mechanical properties and in vitro degradation behavior of Mg−1.0Yb cast alloy 认领 引用
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作者 Zhuo-zhang WEN Lu LI +5 位作者 Xue BAI Wei ZHOU Zhen-ni ZHOU Peng XUE Jing LI Xian-quan JIANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2025年第3期765-787,共23页
The effects of Zr addition on the mechanical properties and in vitro degradation behavior of Mg-1.0Yb-xZr(x=0,0.2,1.0,and 1.53,wt.%)cast alloys were investigated.The results indicated that with increasing Zr addition,... The effects of Zr addition on the mechanical properties and in vitro degradation behavior of Mg-1.0Yb-xZr(x=0,0.2,1.0,and 1.53,wt.%)cast alloys were investigated.The results indicated that with increasing Zr addition,a much refined and homogeneous equiaxed grain structure was achieved from a typical columnar grain structure,in companion with the appearance and coarsening of Zr-rich particles.Subsequent electrochemical and immersion tests demonstrated that the corrosion of the alloy was Zr-addition dependent.A trace or excessive Zr addition caused severe localized corrosion attacks,whereas Zr-free and 1.0 Zr alloyed counterparts were generally corroded uniformly.The good combination of mechanical properties and corrosion resistance of the Mg-1.0Yb-1.0Zr alloy was resulted from the refined and homogeneous equiaxed grain structure and fine dispersed Zr-rich particles,thus improving the comprehensive mechanical properties by grain refinement and reducing corrosion rate by generating a more stable and compact passivation layer during long-term immersion. 展开更多
关键词 Mg-Yb alloy zirconium addition microstructure mechanical properties corrosion behavior
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‘琐琐’葡萄与变异材料果实生长发育动态分析及ISSR分子标记鉴定 认领 引用
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作者 彭雪 杨彤辉 +4 位作者 杨禧雨 刘春燕 刘晶晶 王灵哲 周龙 《西北农业学报》 CAS CSCD 北大核心 2026年第7期1251-1259,共9页
为探究‘琐琐’葡萄与变异材料间的性状变异及遗传差异,明确变异材料的育种潜力和生产利用价值,以‘琐琐’葡萄与变异材料的果实和幼嫩叶片为试验材料,对两者不同生长发育期的果实进行形态学测定、分析两材料间的倍性水平、采用石蜡切... 为探究‘琐琐’葡萄与变异材料间的性状变异及遗传差异,明确变异材料的育种潜力和生产利用价值,以‘琐琐’葡萄与变异材料的果实和幼嫩叶片为试验材料,对两者不同生长发育期的果实进行形态学测定、分析两材料间的倍性水平、采用石蜡切片技术对两材料进行细胞学观察,并结合ISSR分子标记技术分析‘琐琐’葡萄与变异材料间的遗传差异。结果表明,变异材料的平均横径、平均纵径、平均单果质量分别是‘琐琐’葡萄的1.8、1.8和4.4倍,变异材料和‘琐琐’葡萄差异显著(P<0.05)。流式细胞结果显示变异材料与‘琐琐’葡萄的染色体倍性一致,均为二倍体。石蜡切片结果显示,变异材料的果肉细胞体积和细胞数目均显著高于‘琐琐’葡萄,两材料呈现极显著差异。ISSR分子标记分析表明,‘琐琐’葡萄与变异材料间的多态性比例为23.26%、遗传相似系数为0.7674,确定变异材料为‘琐琐’葡萄基因水平的变异。通过表型性状考察、显微结构观察及分子鉴定,明确了‘琐琐’葡萄与变异材料的表型变异和细胞学、遗传差异。变异材料为‘琐琐’葡萄遗传上稳定的大果变异体,具有成为大果型新品种的遗传基础,可作为进一步研究‘琐琐’葡萄大果变异机理的独特材料。 展开更多
关键词 ‘琐琐’葡萄 果实发育 石蜡切片 ISSR标记 鉴定 芽变品种
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伊犁河谷小檗属植物表型多样性研究 认领 引用
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作者 杨禧雨 李茹雪 +2 位作者 陆彪 彭雪 周龙 《新疆农业大学学报》 CAS 2026年第1期71-78,共8页
为探究伊犁河谷小檗属(Berberis L.)不同居群表型性状的多样性水平与变异来源,明确其种质资源保护与利用的理论依据,本研究以新疆伊犁河谷14个自然居群的96份野生小檗属植物为研究对象,测定其叶长、叶宽、叶柄长、新梢长、新梢粗、茎刺... 为探究伊犁河谷小檗属(Berberis L.)不同居群表型性状的多样性水平与变异来源,明确其种质资源保护与利用的理论依据,本研究以新疆伊犁河谷14个自然居群的96份野生小檗属植物为研究对象,测定其叶长、叶宽、叶柄长、新梢长、新梢粗、茎刺数目、茎刺长、花数目、花瓣长、花瓣宽、花冠直径、柱头高度、雄蕊高、花梗长度、果柄长、果实横径、果实纵径、单果重及果色,采用巢式方差分析、主成分分析、聚类分析及Shannon-Wiener多样性指数,综合评价表型变异结构与居群分化特征。结果表明,小檗属植物表型多样性丰富,Shannon-Wiener多样性指数变幅为0.32~1.51,其中18个性状(占94.74%)的指数高于1.0;巢式方差分析显示,表型变异以居群间分化为主,居群间变异占总变异的78.46%,居群内变异占21.54%,表型分化系数(Vst)变幅为64.36%~93.61%,均值达78.46%,其中果实横径(93.61%)、果实纵径(89.16%)等8个性状Vst值高于75%,表明居群间分化显著;主成分分析提取的前5个主成分累计贡献率为71.52%,第1主成分(PC1)和第2主成分(PC2)分别代表叶长-雄蕊高因子与果柄-花梗长度因子,为主要变异维度;聚类分析将14个居群划分为2大类群,其中类群Ⅰ居群均位于研究区域东部(经度≥82°06'E),类群Ⅱ居群均位于研究区域西部(经度≤81°57'E),聚类结果与伊犁河谷东西部地理单元划分基本吻合,表明地理隔离是驱动居群表型分化的主导因素之一。本研究明确了伊犁河谷野生小檗具有丰富的表型多样性,其变异主要来源于居群间分化(78.46%),居群内变异仅占21.54%,研究结果可为该地区小檗属植物的资源保护、种质筛选及生态恢复提供科学依据。 展开更多
关键词 小檗属 种质资源 表型多样性 巢式方差分析 主成分分析
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《神农本草经》与经方应用之麻黄篇 认领 引用
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作者 彭雪 张岱泽 +1 位作者 白湘玉 袁红霞 《山东中医药大学学报》 2026年第1期42-46,91,共5页
麻黄是经方常用药物之一,《神农本草经》描述其功效为“主中风伤寒头痛,温疟发表出汗,去邪热气,止咳逆上气,除寒热,破癥坚积聚”。《伤寒杂病论》以《神农本草经》中麻黄功效为基础,进行药物配伍形成短小精炼的经典方剂,至今仍有深刻影... 麻黄是经方常用药物之一,《神农本草经》描述其功效为“主中风伤寒头痛,温疟发表出汗,去邪热气,止咳逆上气,除寒热,破癥坚积聚”。《伤寒杂病论》以《神农本草经》中麻黄功效为基础,进行药物配伍形成短小精炼的经典方剂,至今仍有深刻影响。如麻黄“主中风伤寒头痛”,多配伍桂枝、苦杏仁、葛根、石膏,以麻黄汤、葛根汤、大青龙汤为代表方;主“温疟发表出汗,去邪热气”,多配伍桂枝、芍药、石膏,以桂枝二越婢一汤为代表方;主“止咳逆上气,除寒热”,多配伍射干、石膏、半夏、细辛、五味子,以小青龙加石膏汤、射干麻黄汤、越婢加半夏汤、麻黄杏仁甘草石膏汤等为代表方;主“破癥坚积聚”,多配伍桂枝,附子,芍药,以桂枝芍药知母汤、乌头汤为代表方。张仲景在继承《神农本草经》麻黄功效的同时进行发展与创新,如利水消肿。应用麻黄时应互参《神农本草经》及《伤寒杂病论》。 展开更多
关键词 《神农本草经》 《伤寒杂病论》 麻黄 中风伤寒头痛 温疟 止咳逆上气 破癥坚积聚
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Influence of heat treatment on microstructure of a newβ-solidifyingγ-TiAl alloy 认领 引用 被引量：1
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作者 Li Quan Xiao-bing Li +5 位作者 Peng Xue Jun-jie Hao Kun Qian Bo Chen Jian-zhong Li Kui Liu 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2025年第1期239-248,共10页
The high strength and stability of the full-lamellar structure guarantee the industrial application of theβ-solidifyingγ-TiAl alloys.However,it is a huge challenge to design an alloy with good hot-deformability as w... The high strength and stability of the full-lamellar structure guarantee the industrial application of theβ-solidifyingγ-TiAl alloys.However,it is a huge challenge to design an alloy with good hot-deformability as well as the full-lamellar structure.The low-cost Ti-42.5Al-2Mn-0.4Mo-0.1B-0.1C(at.%)alloy was designed,which undergoes bothβandαsingle-phase region during the solidification.It is found that the full-lamellar structure can be obtained by the solution heat treatment at 1230℃ for 20 min and then aging treatment at 800℃ for 3 h.Interestingly,a new microstructure,namely,the pearlitic-like microstructure(PM)induced by theα2/γ→βo+γcellular reaction was observed when the aging temperature is increased to above 800℃.The volume fraction of the PM is gradually increased from 0%to 25.5%,65%,and 94%according to elevated aging temperature from 800 to 900,1000,and 1050℃,respectively.The mechanism of the reducedα2/γlamellae and PM formation was discussed regarding the heterogeneous distribution ofβstabilizing elements and the interface energy stored inα2/γlamellae. 展开更多
关键词 β-γ-TiAl Alloy design Two-step heat treatment Full-lamellar structure Cellular reaction
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汽车座椅用织物耐磨性能测试方法的对比分析 认领 引用
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作者 彭雪 吴双全 陈华 《产业用纺织品》 2026年第5期48-53,共6页
为对比分析汽车座椅用织物耐磨性能的测试方法,选取机织平布、机织提花布和针织布3种典型织物与海绵复合,制备汽车座椅用织物,再采用马丁代尔法、Taber法、肖伯尔法、平面磨耗法和MIE法等5种方法进行耐磨性能测试。通过构建关于灰色对... 为对比分析汽车座椅用织物耐磨性能的测试方法,选取机织平布、机织提花布和针织布3种典型织物与海绵复合,制备汽车座椅用织物,再采用马丁代尔法、Taber法、肖伯尔法、平面磨耗法和MIE法等5种方法进行耐磨性能测试。通过构建关于灰色对比度与磨损面描述的综合评分体系,量化比较各方法的磨损程度,并分析各测试方法与实际使用场景的对应关系。结果表明:同一织物不同测试方法的耐磨性结果差异显著,这与不同测试方法的摩擦原理、加载方式和磨料特性各异,导致不同方法凸显织物失效模式不同有关。马丁代尔法适合模拟长期乘坐时的多方向累积磨损;Taber法适合模拟砂砾嵌入后的碾压磨削;肖伯尔法适合模拟坐姿扭转、起身等小面积旋转摩擦;平面磨耗法适合模拟上下车时的单向滑动摩擦;MIE法适合模拟较低负荷拉伸状态下较长时间的轻微摩擦,其磨损作用相对最温和。研究为汽车座椅用织物耐磨测试方法的选择提供了依据,并指出评价汽车座椅用织物耐磨性能时,可根据材料实际的使用场景选择或组合相应的测试方法,以更全面地反映材料在实际使用中的耐磨表现。 展开更多
关键词 汽车座椅用织物 耐磨性能 马丁代尔法 Taber法 肖伯尔法 平面磨耗法 MIE法 综合评分体系
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汽车内饰用纺织品耐光色牢度标准的对比分析 认领 引用
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作者 彭雪 吴双全 周雪凤 《天津纺织科技》 2026年第2期44-47,共4页
耐光色牢度是考量汽车内饰用纺织品耐久性的一个关键指标,国内外车企根据其自身所处国家气候环境和产品定位的特性,分别制定了不同的试验方法和技术标准。为便于从业者更好地掌握和使用我国发布的GB/T 32088—2015《汽车及非金属部件及... 耐光色牢度是考量汽车内饰用纺织品耐久性的一个关键指标,国内外车企根据其自身所处国家气候环境和产品定位的特性,分别制定了不同的试验方法和技术标准。为便于从业者更好地掌握和使用我国发布的GB/T 32088—2015《汽车及非金属部件及材料氙灯加速老化试验方法》国家标准,文中对国内外汽车内饰用纺织品耐光色牢度的相关标准进行了分类和详细介绍,同时分析比较了国家标准与不同车企(德系、美系、日系)标准在试样准备、试验参数、等级评定、技术要求等方面的异同之处,建议广大车企积极采用我国标准,同时也指出了该标准目前存在的不足,以期完善我国汽车内饰用纺织品耐光色牢度的检测标准,推动我国汽车内饰用纺织品行业的经济增长。 展开更多
关键词 汽车内饰用纺织品 耐光色牢度 国家标准 差异 分析
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智慧护理在孕产妇母乳喂养中的应用:一项范围综述 认领 引用
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作者 彭雪 刘霞 +3 位作者 陈霞 赵海燕 刘进 张叶 《当代护士（上旬刊）》 2026年第8期19-28,共10页
目的采用范围综述的方法总结智慧护理在孕产妇母乳喂养中应用的现状、影响及结局指标,指出现有研究的不足,为未来研究及临床实践提供参考。方法本研究对6个数据库进行检索,具体包括Web of Science、PubMed、ProQuest、中国知网、万方数... 目的采用范围综述的方法总结智慧护理在孕产妇母乳喂养中应用的现状、影响及结局指标,指出现有研究的不足,为未来研究及临床实践提供参考。方法本研究对6个数据库进行检索,具体包括Web of Science、PubMed、ProQuest、中国知网、万方数据知识服务平台、中国生物医学文献数据库。检索时限:自建库之日至2025年7月6日。结果最终纳入40篇文献。智慧护理形式呈现多样性,包括宣教视频、应用程序(application,App)、微信、电话咨询、社交媒体等。智慧护理在孕产妇母乳喂养中应用的结局指标包括母乳喂养指标、行为指标、婴儿指标和生活相关指标等。结论智慧护理对提高孕产妇纯母乳喂养率、改善母乳喂养态度及提升母乳喂养自我效能感等方面有积极作用,但是也可能会使孕产妇的智能手机成瘾水平升高。基于智慧护理的孕产妇母乳喂养App数量逐渐增多。母乳喂养可以促进母婴互动,进一步增进母婴感情。此外,母乳喂养可以提高护理满意度及健康教育满意度等。 展开更多
关键词 智慧护理 孕产妇 母乳喂养 范围综述
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Erratum to:Strengthening strategy for high-performance friction stir lap welded joints based on 5083 Al alloy 认领 引用
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作者 Yujia Shen Jijie Wang +5 位作者 Beibei Wang Peng Xue Fengchao Liu Dingrui Ni Bolv Xiao Zongyi Ma 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2025年第4期973-973,共1页
Erratum to:International Journal of Minerals,Metallurgy and Materials Volume 31,Number 11,November 2024,Page 2498 http://gffzzd3cc09b8251d45dfs990u65bk660p6bxn.ffgz.tsg.suse.edu.cn/10.1007/s12613-024-2847-2 In this article,the fund number in the acknowledgements has b... Erratum to:International Journal of Minerals,Metallurgy and Materials Volume 31,Number 11,November 2024,Page 2498 http://gffzzd3cc09b8251d45dfs990u65bk660p6bxn.ffgz.tsg.suse.edu.cn/10.1007/s12613-024-2847-2 In this article,the fund number in the acknowledgements has been erroneously given as the Program for Guangdong Basic and Applied Basic Research Foundation,China(No.2021A151511006)It should be as follows:the Program for Guangdong Basic and Applied Basic Research Foundation,China(No.2021A1515110061). 展开更多
关键词 welded friction alloy
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肺宁合剂联合常规西医治疗对AECOPD患者肺功能及炎症指标的影响 认领 引用
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作者 彭雪 蒋婷婷 赵涛 《分子诊断与治疗杂志》 2026年第3期655-657,661,共3页
目的探讨肺宁合剂联合常规西医治疗对慢性阻塞性肺疾病急性加重期(AECOPD)患者肺功能及血小板与淋巴细胞比值(PLR)、中性粒细胞与血小板比值(NPR)、淋巴细胞与C-反应蛋白比值(LCR)等炎症指标的影响。方法选取2022年9月至2023年12月于南... 目的探讨肺宁合剂联合常规西医治疗对慢性阻塞性肺疾病急性加重期(AECOPD)患者肺功能及血小板与淋巴细胞比值(PLR)、中性粒细胞与血小板比值(NPR)、淋巴细胞与C-反应蛋白比值(LCR)等炎症指标的影响。方法选取2022年9月至2023年12月于南京中医药大学宿迁附属医院就诊的100例AECOPD患者,采用抛硬币法分为联合组(n=50,给予硫酸沙丁胺醇雾化吸入和哌拉西林钠他唑巴坦钠静脉滴注的同时联合肺宁合剂口服治疗)和西医组(n=50,硫酸沙丁胺醇雾化吸入和哌拉西林钠他唑巴坦钠静脉滴注),疗程为14 d。比较两组证候积分、疗效、肺功能指标[第一秒用力呼气容积占预计值百分比(FEV1%pred)、肺总容量(TLC)、第一秒用力呼气容积/用力肺活量(FEV1/FVC)]、炎症指标(PLR、NPR、LCR)、不良反应。结果治疗后,联合组证候积分低于西医组、总有效率高于西医组,差异有统计学意义(P0.05)。结论肺宁合剂有利于提升AECOPD患者治疗效果,改善患者肺功能、减轻患者炎症反应,且未提高不良反应发生率。 展开更多
关键词 慢性阻塞性肺疾病急性加重期 肺宁合剂 硫酸沙丁胺醇 哌拉西林钠他唑巴坦钠
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