Soil erosion induced by rainfall on slopes poses a significant threat to land sustainability and ecological balance.Enzyme-induced calcium carbonate precipitation(EICP),as an emerging environmentally friendly biominer...Soil erosion induced by rainfall on slopes poses a significant threat to land sustainability and ecological balance.Enzyme-induced calcium carbonate precipitation(EICP),as an emerging environmentally friendly biomineralization technology,can form a stable crust layer on slopes,effectively reducing rainwater infiltration and enhancing soil erosion resistance.This study designed rainfall erosion model tank tests using soybean urease and cementation solution.The treatment effects were evaluated through macro and microscopic indicators,and the hydrological response of the slope under different rainfall conditions was analysed.The results indicate the calcium carbonate content(CCC)and crust thickness of the slope gradually increase while tend to saturate with treatments.The slope gradient exhibits a controlling influence on the crust distribution,with a systematic downslope shift in the peak thickness zone as the gradient increases.At the microscopic level,with the increase of treatment cycles,the pore volume is significantly reduced,and the particle surface is extensively coated with CaCO₃precipitates.From a geomorphological perspective,untreated slopes develop rapid and deep gully networks,while treated slopes transition to smoother and more stable surfaces.Under high rainfall intensity,the erosion amount for the slope with ten cycles of treatment reduced significantly,and the maximum gully width and depth exhibit a decreasing trend with erosion amount.The surface runoff rate reaches the optimal performance after seven cycles of treatment,where a continuous uniform CaCO₃crust significantly increases the runoff rate.The relationship for erosion,runoff rate,and infiltration coefficient with more treatments reflects a coordinated trend.展开更多
Traditional Chinese medicine(TCM)serves as a treasure trove of ancient knowledge,holding a crucial position in the medical field.However,the exploration of TCM's extensive information has been hindered by challeng...Traditional Chinese medicine(TCM)serves as a treasure trove of ancient knowledge,holding a crucial position in the medical field.However,the exploration of TCM's extensive information has been hindered by challenges related to data standardization,completeness,and accuracy,primarily due to the decen-tralized distribution of TCM resources.To address these issues,we developed a platform for TCM knowledge discovery(TCMKD,http://gffzz550319536f6144acs6q5xowovvxkf65n5.ffgz.tsg.suse.edu.cn/TCMKD/).Seven types of data,including syndromes,formulas,Chinese patent drugs(CPDs),Chinese medicinal materials(CMMs),ingredients,targets,and diseases,were manually proofread and consolidated within TCMKD.To strengthen the integration of TCM with modern medicine,TCMKD employs analytical methods such as TCM data mining,enrichment analysis,and network localization and separation.These tools help elucidate the molecular-level commonalities between TCM and contemporary scientific insights.In addition to its analytical capabilities,a quick question and answer(Q&A)system is also embedded within TCMKD to query the database efficiently,thereby improving the interactivity of the platform.The platform also provides a TCM text annotation tool,offering a simple and efficient method for TCM text mining.Overall,TCMKD not only has the potential to become a pivotal repository for TCM,delving into the pharmaco-logical foundations of TCM treatments,but its flexible embedded tools and algorithms can also be applied to the study of other traditional medical systems,extending beyond just TCM.展开更多
Aiming to address the Unmanned Aerial Vehicle(UAV) formation collision avoidance problem in Three-Dimensional(3-D) low-altitude environments where dense various obstacles exist, a fluid-based path planning framework n...Aiming to address the Unmanned Aerial Vehicle(UAV) formation collision avoidance problem in Three-Dimensional(3-D) low-altitude environments where dense various obstacles exist, a fluid-based path planning framework named the Formation Interfered Fluid Dynamical System(FIFDS) with Moderate Evasive Maneuver Strategy(MEMS) is proposed in this study.First, the UAV formation collision avoidance problem including quantifiable performance indexes is formulated. Second, inspired by the phenomenon of fluids continuously flowing while bypassing objects, the FIFDS for multiple UAVs is presented, which contains a Parallel Streamline Tracking(PST) method for formation keeping and the traditional IFDS for collision avoidance. Third, to rationally balance flight safety and collision avoidance cost, MEMS is proposed to generate moderate evasive maneuvers that match up with collision risks. Comprehensively containing the time and distance safety information, the 3-D dynamic collision regions are modeled for collision prediction. Then, the moderate evasive maneuver principle is refined, which provides criterions of the maneuver amplitude and direction. On this basis, an analytical parameter mapping mechanism is designed to online optimize IFDS parameters. Finally, the performance of the proposed method is validated by comparative simulation results and real flight experiments using fixed-wing UAVs.展开更多
Increasingly identified alternative biome states in terrestrial ecosystems have raised significant concerns about nonlinear transitions among these states and the accompanying catastrophic consequences.As a hotspot of...Increasingly identified alternative biome states in terrestrial ecosystems have raised significant concerns about nonlinear transitions among these states and the accompanying catastrophic consequences.As a hotspot of global biodiversity,Australian terrestrial ecosystems provide precious habitats for numerous unique organisms.However,whether these ecosystems are formed as alternative biome states and may respond nonlinearly to environmental stress remains unclear.Here,we identified four alternative biome states of Australian terrestrial ecosystems,including forest,savanna,grassland,and shrubland,by conducting potential analyses on the eigen-coverage of different ecosystem types along the climatic gradients.The four biome states,characterized by distinct growth forms and eigen-coverages of the dominant plants,exhibited wide climatic niches that extensively overlap with one another,indicting a high level of alternativity among these states.We further revealed variations in fire frequency,soil organic carbon content,and livestock density among the biome states,which potentially explain the maintenance of alternative biome states under similar climatic conditions in relation to theoretical positive feedbacks.Our findings indicate the prevalence and regionality of alternative biome states in terrestrial ecosystems.Given the trends in global warming and intensifying disturbances,we highlight the necessity of increased attention to nonlinear ecosystem degradation among terrestrial biome states.展开更多
Because of their great therapeutic and economic value,medicinal plants have attracted increasing scientific attention.With the rapid development of high-throughput sequencing technology,the genomes of many medicinal p...Because of their great therapeutic and economic value,medicinal plants have attracted increasing scientific attention.With the rapid development of high-throughput sequencing technology,the genomes of many medicinal plants have been sequenced.Storing and analyzing the increasing volume of genomic data has become an urgent task.To solve this challenge,we have proposed the Traditional ChineseMedicine Plant Genome database(TCMPG,http://gffzz550319536f6144ach6q5xowovvxkf65n5.ffgz.tsg.suse.edu.cn/TCMPG/),an integrative database for storing the scattered genomes of medicinal plants.TCMPG currently includes 160 medicinal plants,195 corresponding genomes,and 255 herbal medicines.Detailed information on plant species,genomes,and herbal medicines is also integrated into TCMPG.Popular genomic analysis tools are embedded in TCMPG to facilitate the systematic analysis of medicinal plants.These include BLAST for identifying orthologs from different plants,SSR Finder for identifying simple sequence repeats,JBrowse for browsing genomes,Synteny Viewer for displaying syntenic blocks between two genomes,and HmmSearch for identifying protein domains.TCMPG will be continuously updated by integrating new data and tools for comparative and functional genomic analysis.展开更多
The feasibility of employing shell powder as a novel bio-filler to prepare fluorocarbon coating is demonstrated.According to the relevant Chinese standards, the thermal and mechanical properties of the shell powder-fi...The feasibility of employing shell powder as a novel bio-filler to prepare fluorocarbon coating is demonstrated.According to the relevant Chinese standards, the thermal and mechanical properties of the shell powder-filled fluorocarbon coating were evaluated, and compared with those filled by commercial calcium carbonate. All the shell powder-filled coatings can meet the requirements stated in the relevant standards, and with decreasing the particle size of the shell powders, the performance of the thermal insulation coating is enhanced. The coating(SC3) filled by shell powders with an average particle size of 2.81 μm possesses a better thermal insulation performance than the coating(CC) filled by commercial calcium carbonate. The coating SC3 has comparable adhesive force and washing resistance with the coating CC, and in the washing resistance test, after 2000 cycles, the coating SC3 was still able to cover totally their substrates. This work demonstrates a high value-added disposal method for the aquacultural wastes.展开更多
Waste shell stacking with odor and toxicity is a serious hazard to our living environment. To make effective use of the natural resources, the shell powder was applied as a filler of outdoor thermal insulation coating...Waste shell stacking with odor and toxicity is a serious hazard to our living environment. To make effective use of the natural resources, the shell powder was applied as a filler of outdoor thermal insulation coatings. Sodium stearate(SS) was used to modify the properties of shell powder to reduce its agglomeration and to increase its compatibility with the emulsion. The oil absorption rate and the spectrum reflectance of the shell powder show that the optimized content of SS as a modifier is 1.5wt%. The total spectrum reflectance of the coating made with the shell powder that is modified at this optimum SS content is 9.33% higher than that without any modification. At the optimum SS content of 1.5wt%, the thermal insulation of the coatings is improved by 1.0℃ for the cement mortar board and 1.6℃ for the steel plate, respectively. The scouring resistance of the coating with the 1.5wt% SS-modified shell powder is three times that of the coating without modification.展开更多
Despite the high prevalence of straight back syndrome(SBS),there is still limited research on this condition,posing challenges for effective diagnosis and treatment.The disease has been known for a long time,but there...Despite the high prevalence of straight back syndrome(SBS),there is still limited research on this condition,posing challenges for effective diagnosis and treatment.The disease has been known for a long time,but there have been few related studies,which mostly consist of case reports.These studies have not been systematically summarized,making it difficult to meet the current needs of diagnosis and treatment.This article summarized the existing literature and comprehensively reviewed the diagnosis,pathogenesis,treatment,and research status of mitral valve prolapse related to SBS.We specifically emphasized the mechanisms and prognosis of SBS combined with mitral valve prolapse and discussed the latest research progress in this disease.展开更多
Rotational manipulation of massive particles and biolo gical samples is essential for the development of miniaturized lab-on-a-chip platforms in the fields of chemical,medical,and biological applications.In this paper...Rotational manipulation of massive particles and biolo gical samples is essential for the development of miniaturized lab-on-a-chip platforms in the fields of chemical,medical,and biological applications.In this paper,a device concept of a two-dimensional acoustofluidic chamber actuated by multiple nonlinear vibration sources is proposed.The functional chamber enables the generation of acoustic streaming vortices for potential applications that include strong mixing of multiphase flows and rotational manipulation of micro-ano-scale objects without any rotating component.Using numerical simulations,we find that diversified acoustofluidic fields can be generated in the chamber under various actuations,and massive polystyrene beads inside can experience different acoustophoretic motions under the combined effect of an acoustic radiation force and acoustic streaming.Moreover,we investigate and clarify the effects of structural design on modulation of the acoustofluidic fields in the chamber.We believe the presented study could not only provide a promising potential tool for rotational acoustofluidic manipulation,but could also bring this community some useful design insights into the achievement of desired acoustofluidic fields for assorted microfluidic applications.展开更多
Objective:To calculate the focus absorption dose of 153Sm-EDTMP with the Monte Carlo(MC)EGS4 method for treatment of bone metastases from nasopharyngeal carcinoma or breast cancer,and investigate the relationship betw...Objective:To calculate the focus absorption dose of 153Sm-EDTMP with the Monte Carlo(MC)EGS4 method for treatment of bone metastases from nasopharyngeal carcinoma or breast cancer,and investigate the relationship between the focus absorption dose and painkilling effect of 153Sm-EDTMP.Methods:Four patients with multiple bone metastases from nasopharyngeal or breast carcinoma and suffered from grade IV bone pain were treated with radionuclide internal irradiation of 153Sm-EDTMP.The absorption dose and dose distribution of bone metastases and other targeted organs were calculated with MC EGS4 program based on the time-order SPECT/CT scanning and the measurement of the radioactivity in the urine accumulation.The release of bone pain and the improvement of life quality were observed.Results:Bone pain of the patients was significantly alleviated to grade II for 3–4 weeks after internal 153Sm-EDTMP irradiation.The 3-dimensional absorption dose distribution image of bone metastases and targeted organs showed that the dose distribution in bone metastases was not asymmetrical.After injection of 0.65×37 MBq/kg 153Sm-EDTMP,the highest absorption dose in bone lesions was about 4.9–5.9 Gy,and the dose in the lesion margin was about 2.0 Gy.Using the highest dose as reference dose point,the relative absorption dose values of bone marrow,vertebra and sex organ near lesions were 0.48–1.1 Gy,0.51–0.85 Gy,and 0.01–0.14 Gy,respectively.Conclusion:The absorption dose of bone metastases is significantly lower than treatment dose of 30 Gy after single irradiation of 153Sm-EDTMP.The painkilling effect is limited and in accordance with clinical observation.展开更多
A practical protocol to obtain 1,1′-binaphthyl-2,2′-diamine was developed from 2-naphthol and 2-naphthylhydrazine under mild conditions:solvent-free,125-130℃,atmospheric pressure.The convenient procedure makes the ...A practical protocol to obtain 1,1′-binaphthyl-2,2′-diamine was developed from 2-naphthol and 2-naphthylhydrazine under mild conditions:solvent-free,125-130℃,atmospheric pressure.The convenient procedure makes the process amenable for large-scale synthesis of the versatile compound.展开更多
Several studies have largely focused on the significant role of the nervous and immune systems in the process of tumorigenesis, including tumor growth, proliferation, apoptosis, and metastasis. The brain-gut-axis is a...Several studies have largely focused on the significant role of the nervous and immune systems in the process of tumorigenesis, including tumor growth, proliferation, apoptosis, and metastasis. The brain-gut-axis is a new paradigm in neuroscience, which describes the biochemical signaling between the gastrointestinal (GI) tract and the central nervous system. This axis may play a critical role in the tumorigenesis and development of GI cancers. Mechanistically, the bidirectional signal transmission of the brain-gut-axis is complex and remains to be elucidated. In this article, we review the current findings concerning the relationship between the brain-gut axis and GI cancer cells, focusing on the significant role of the brain-gut axis in the processes of tumor proliferation, invasion, apoptosis, autophagy, and metastasis. It appears that the brain might modulate GI cancer by two pathways: the anatomical nerve pathway and the neuroendocrine route. The simulation and inactivation of the central nervous, sympathetic, and parasympathetic nervous systems, or changes in the innervation of the GI tract might contribute to a higher incidence of GI cancers. In addition, neurotransmitters and neurotrophic factors can produce stimulatory or inhibitory effects in the progression of GI cancers. Insights into these mechanisms may lead to the discovery of potential prognostic and therapeutic targets.展开更多
Soil texture is an indicator of soil physical structure which delivers many ecological functions of soils such as thermal regime, plant growth, and soil quality. However, traditional methods for soil texture measureme...Soil texture is an indicator of soil physical structure which delivers many ecological functions of soils such as thermal regime, plant growth, and soil quality. However, traditional methods for soil texture measurement are time-consuming and labor-intensive. This study attempts to explore an indirect method for rapid estimating the texture of three subgroups of purple soils (i.e. calcareous, neutral, and acidic). 190 topsoil (0 - 10 cm) samples were collected from sloping croplands in Tongnan and Beibei Districts of Chongqing Municipality in China. Vis-NIR spectrum was measured and processed, and stepwise multiple linear regression (SMLR), partial least squares regression (PLSR), and back propagation neural network (BPNN) models were constructed to inform the soil texture. The clay fractions ranged from 4.40% to 27.12% while sand fractions ranged from 0.34% to 36.57%, hereby soil samples encompass three textural classes (i.e. silt, silt loam, and silty clay loam). For the original spectrum, the texture of calcareous and neutral purple soils was not significantly correlated with spectral reflectance and linear models (SMLR and PLSR) exhibited low prediction accuracy. The correlation coefficients and the goodness-of-fits between soil texture and the transformed spectra of all soil groups increased by continuum-removal (CR), first-order differential (R'), and second-order differential (R") transformations. Among them, the R" had the best performance in terms of improving the correlation coefficients and the goodness-of-fits. For the calcareous purple soil, the SMLR exceeds PLSR and BPNN with a higher coefficient of determination (R2) and the ratio of performance to inter-quartile distance (RPIQ) values and lower root mean square error of validation (RMSEV), but for the neutral and acidic purple soils, the PLSR model has a better prediction accuracy. In summary, the linear methods (SMLR and PLSR) are more reliable in estimating the texture of the three purple soil groups when using Vis-NIR spectroscopy inversion.展开更多
Rechargeable magnesium-ion(Mg-ion)batteries have attracted wide attention for energy storage.However,magnesium anode is still limited by the irreversible Mg plating/stripping procedure.Herein,a well-designed binary Bi...Rechargeable magnesium-ion(Mg-ion)batteries have attracted wide attention for energy storage.However,magnesium anode is still limited by the irreversible Mg plating/stripping procedure.Herein,a well-designed binary Bi2O3-Bi2S3(BO-BS)heterostructure is fulfilled by virtue of the cooperative interface and energy band engineering targeted fast Mg-ion storage.The built-in electronic field resulting from the asymmetrical electron distribution at the interface of electron-rich S center at Bi2S3 side and electron-poor O center at Bi2O3 side effectively accelerates the electrochemical reaction kinetics in the Mg-ion battery system.Moreover,the as-designed heterogenous interface also benefits to maintaining the electrode integrity.With these advantages,the BO-BS electrode displays a remarkable capacity of 150.36 mAh g−1 at 0.67 A g-1 and a superior cycling stability.This investigation would offer novel insights into the rational design of functional heterogenous electrode materials targeted the fast reaction kinetics for energy storage systems.展开更多
Tribenuron methyl (TBM) is a member of the sulfonylurea herbicide family and is widely used worldwide. In this study, TBM- degrading bacteria were enriched with TBM as potential carbon, nitrogen or sulfur source, an...Tribenuron methyl (TBM) is a member of the sulfonylurea herbicide family and is widely used worldwide. In this study, TBM- degrading bacteria were enriched with TBM as potential carbon, nitrogen or sulfur source, and 44 bacterial isolates were obtained. These isolates were phylogenetically diverse, and were grouped into 25 operational taxonomic units and 14 currently known genera. Three representatives, Bacillus sp. strain BS2, Microbacterium sp. strain BS3, and Cellulosimicrobium sp. strain BSI 1, were selected, and their growth and TBM removal from culture broth were investigated. In addition, indigenous earthworms were collected and applied to augment TBM degradation in lab-scale soil column experiments. Results demonstrated that Bacillus sp. strain BS2 and earthworms significantly increased TBM removal during soil column experiments.展开更多
Multiarm star block copolymers hyperbranched polyethylenimine-b-poly(2-hydroxyethyl methacrylate) (HPEI-b- PHEMA) with average 28 PHEMA arms have been prepared by atom transfer radical polymerization (ATRP) of H...Multiarm star block copolymers hyperbranched polyethylenimine-b-poly(2-hydroxyethyl methacrylate) (HPEI-b- PHEMA) with average 28 PHEMA arms have been prepared by atom transfer radical polymerization (ATRP) of HEMA in a mixed solvent of methanol and water using a core-first strategy. The hyperbranched macroinitiator employed was prepared on the basis of well-defined hyperbranched polyethylenimine with Mw/Mn of 1.04 by amidation with 2-bromo-isobutyryl bromide. The polymerization condition was optimized to prepare star copolymers with narrow dispersity, and the variables included the volume ratio of methanol to water, the molar ratio of initiating site to CuC1 and the molar ratio of [CuCl]:[CuBr2]. Under the optimized polymerization condition, the lowest Mw/Mn value of the obtained star copolymers was around 1.3. Kinetic analysis showed that an induction period existed in the polymerization of HEMA. After this induction period, a linear dependence of ln([M]0/[M]t) on time was observed. The obtained HPEI-b-PHEMA could adsorb hydrophilic molecules. The comparison with the star copolymer with hydrophobic core and hydrophilic PHEMA shell verified that both the hydrophilic core and shell could host the hydrophilic guests, but the amidated HPEI core was more effective than the PHEMA shell.展开更多
Patients with novel coronavirus disease-19(COVID-19)pneumonia continue to have problems with respiratory function,physical and psychological function,the ability to perform activities of daily living,and social partic...Patients with novel coronavirus disease-19(COVID-19)pneumonia continue to have problems with respiratory function,physical and psychological function,the ability to perform activities of daily living,and social participation after discharge from the hospital.As such,strengthening rehabilitation treatments for discharged patients and relapse prevention after recovery are important aspects of the prevention and control of COVID-19.This paper combined the principles and practices of in Chinese and Western medicine and compiled the recommendations of both for home rehabilitation in the post-COVID-19 epidemic stage.The purpose of this paper is to facilitate the self-rehabilitation of patients with COVID-19 and to promote the prevention and control of COVID-19 at this current stage.展开更多
本文介绍了名为ACU&MOX-DATA(Acupuncture&moxibustion-deep analysis to treat accurately)的针灸多组学异源数据融合分析网络平台(http://gffzz550319536f6144ach6q5xowovvxkf65n5.ffgz.tsg.suse.edu.cn/ACU&MOX-DATA/)。该平台旨在整合分析针灸相关疾病、临床和实...本文介绍了名为ACU&MOX-DATA(Acupuncture&moxibustion-deep analysis to treat accurately)的针灸多组学异源数据融合分析网络平台(http://gffzz550319536f6144ach6q5xowovvxkf65n5.ffgz.tsg.suse.edu.cn/ACU&MOX-DATA/)。该平台旨在整合分析针灸相关疾病、临床和实验室获得的异源、多层次数据,其典型特点是在中医理论指导下,收集针灸研究所获得的各种观测指标,通过异源、多层次数据融合分析的方法,实现对针灸学领域关键科学问题的集成分析和可视化解读。本文介绍了该平台目前已有的功能及未来的研究计划。展开更多
Objectives:This paper aims to explore application effect of the dual-perspective care mode for safety and comfort needs in patients with magnetic resonance imaging(MRI)examination.Methods:A total of 132 patients with ...Objectives:This paper aims to explore application effect of the dual-perspective care mode for safety and comfort needs in patients with magnetic resonance imaging(MRI)examination.Methods:A total of 132 patients with MRI examination who were admitted to our hospital from September 2018 to February 2020 were selected as the research objects,and they were divided into control group and intervention group by random number table method,with 66 cases in each group.Patients in the control group received routine nursing care,while patients in the intervention group received the dual-perspective nursing care.The psychological state,nursing safety quality,nursing satisfaction,and quality of life scores of the two groups were compared and analyzed.Results:The Self-Rating Anxiety Scale(SAS)(32.05±2.63)and Self-Rating Depression Scale(SDS)(33.14±4.15)of patients in the intervention group receiving dual-perspective nursing mode were lower than those in the control group,and the improvement level of psychological states such as anxiety and depression was significantly better than that in the control group,the difference was statistically significant(P<0.05).Intervention group patients in early treatment of dangerous situation(3.26±1.08),implementation of safety measures(3.32±1.15),prevention of accidental injury(3.17±0.95),and other eight nursing safety quality index scores were higher than the control group(P<0.05).The nursing satisfaction of patients in the intervention group(93.94%)was significantly higher than that in the control group(75.76%),and the differences were statistically significant(P<0.05).In addition,the five life quality indexes of the intervention group were higher than those of the control group,including physiological(90.51±6.39),psychological(91.33±5.76),and emotional(90.45±5.39).Conclusion:The dual-perspective nursing intervention for the safety and comfort needs of patients with MRI examination can effectively improve the anxiety and depression in the diagnosis and treatment,ensure the safety and comfort of the examination process,improve patients'satisfaction with nursing,so as to ensure the effectiveness and accuracy of the examination results,which has great clinical application value.展开更多
Diabetic foot ulcers are a prevalent complication that can significantly impact quality of life and necessitate high-level amputations. Hence, early diagnosis and treatment, elucidation of pathogenesis, and targeted c...Diabetic foot ulcers are a prevalent complication that can significantly impact quality of life and necessitate high-level amputations. Hence, early diagnosis and treatment, elucidation of pathogenesis, and targeted countermeasures assume paramount importance. Wound healing entails a complex process wherein various components such as inflammatory cells, extracellular matrix, and immune cells intricately interact with each other. Due to the vulnerability of the skin to damage, inadequate or impaired wound healing has emerged as an urgent clinical challenge requiring resolution. This paper provides a comprehensive overview of the pathogenesis, diagnosis, and treatment of diabetic foot ulcers in order to offer theoretical guidance for specific interventions.展开更多
基金funding support from the National Key Research and Development Program of China(Grant No.2023YFC3707801)National Natural Science Foundation of China(Grant No.52478352)Bureau of Geology and Mineral Exploration of Jiangsu(Grant No.2023KY06).
摘要Soil erosion induced by rainfall on slopes poses a significant threat to land sustainability and ecological balance.Enzyme-induced calcium carbonate precipitation(EICP),as an emerging environmentally friendly biomineralization technology,can form a stable crust layer on slopes,effectively reducing rainwater infiltration and enhancing soil erosion resistance.This study designed rainfall erosion model tank tests using soybean urease and cementation solution.The treatment effects were evaluated through macro and microscopic indicators,and the hydrological response of the slope under different rainfall conditions was analysed.The results indicate the calcium carbonate content(CCC)and crust thickness of the slope gradually increase while tend to saturate with treatments.The slope gradient exhibits a controlling influence on the crust distribution,with a systematic downslope shift in the peak thickness zone as the gradient increases.At the microscopic level,with the increase of treatment cycles,the pore volume is significantly reduced,and the particle surface is extensively coated with CaCO₃precipitates.From a geomorphological perspective,untreated slopes develop rapid and deep gully networks,while treated slopes transition to smoother and more stable surfaces.Under high rainfall intensity,the erosion amount for the slope with ten cycles of treatment reduced significantly,and the maximum gully width and depth exhibit a decreasing trend with erosion amount.The surface runoff rate reaches the optimal performance after seven cycles of treatment,where a continuous uniform CaCO₃crust significantly increases the runoff rate.The relationship for erosion,runoff rate,and infiltration coefficient with more treatments reflects a coordinated trend.
基金supported by Natural Science Foundation of Sichuan,China(Grant No.:2024ZDZX0019).
摘要Traditional Chinese medicine(TCM)serves as a treasure trove of ancient knowledge,holding a crucial position in the medical field.However,the exploration of TCM's extensive information has been hindered by challenges related to data standardization,completeness,and accuracy,primarily due to the decen-tralized distribution of TCM resources.To address these issues,we developed a platform for TCM knowledge discovery(TCMKD,http://gffzz550319536f6144acs6q5xowovvxkf65n5.ffgz.tsg.suse.edu.cn/TCMKD/).Seven types of data,including syndromes,formulas,Chinese patent drugs(CPDs),Chinese medicinal materials(CMMs),ingredients,targets,and diseases,were manually proofread and consolidated within TCMKD.To strengthen the integration of TCM with modern medicine,TCMKD employs analytical methods such as TCM data mining,enrichment analysis,and network localization and separation.These tools help elucidate the molecular-level commonalities between TCM and contemporary scientific insights.In addition to its analytical capabilities,a quick question and answer(Q&A)system is also embedded within TCMKD to query the database efficiently,thereby improving the interactivity of the platform.The platform also provides a TCM text annotation tool,offering a simple and efficient method for TCM text mining.Overall,TCMKD not only has the potential to become a pivotal repository for TCM,delving into the pharmaco-logical foundations of TCM treatments,but its flexible embedded tools and algorithms can also be applied to the study of other traditional medical systems,extending beyond just TCM.
基金supported in part by the National Natural Science Foundations of China(Nos.61175084,61673042 and 62203046)the China Postdoctoral Science Foundation(No.2022M713006).
摘要Aiming to address the Unmanned Aerial Vehicle(UAV) formation collision avoidance problem in Three-Dimensional(3-D) low-altitude environments where dense various obstacles exist, a fluid-based path planning framework named the Formation Interfered Fluid Dynamical System(FIFDS) with Moderate Evasive Maneuver Strategy(MEMS) is proposed in this study.First, the UAV formation collision avoidance problem including quantifiable performance indexes is formulated. Second, inspired by the phenomenon of fluids continuously flowing while bypassing objects, the FIFDS for multiple UAVs is presented, which contains a Parallel Streamline Tracking(PST) method for formation keeping and the traditional IFDS for collision avoidance. Third, to rationally balance flight safety and collision avoidance cost, MEMS is proposed to generate moderate evasive maneuvers that match up with collision risks. Comprehensively containing the time and distance safety information, the 3-D dynamic collision regions are modeled for collision prediction. Then, the moderate evasive maneuver principle is refined, which provides criterions of the maneuver amplitude and direction. On this basis, an analytical parameter mapping mechanism is designed to online optimize IFDS parameters. Finally, the performance of the proposed method is validated by comparative simulation results and real flight experiments using fixed-wing UAVs.
基金supported by the Special Fund for Youth Team of Southwest University(SWU-XDJH-202306).
摘要Increasingly identified alternative biome states in terrestrial ecosystems have raised significant concerns about nonlinear transitions among these states and the accompanying catastrophic consequences.As a hotspot of global biodiversity,Australian terrestrial ecosystems provide precious habitats for numerous unique organisms.However,whether these ecosystems are formed as alternative biome states and may respond nonlinearly to environmental stress remains unclear.Here,we identified four alternative biome states of Australian terrestrial ecosystems,including forest,savanna,grassland,and shrubland,by conducting potential analyses on the eigen-coverage of different ecosystem types along the climatic gradients.The four biome states,characterized by distinct growth forms and eigen-coverages of the dominant plants,exhibited wide climatic niches that extensively overlap with one another,indicting a high level of alternativity among these states.We further revealed variations in fire frequency,soil organic carbon content,and livestock density among the biome states,which potentially explain the maintenance of alternative biome states under similar climatic conditions in relation to theoretical positive feedbacks.Our findings indicate the prevalence and regionality of alternative biome states in terrestrial ecosystems.Given the trends in global warming and intensifying disturbances,we highlight the necessity of increased attention to nonlinear ecosystem degradation among terrestrial biome states.
基金supported by the National Natural Science Foundation of China(Nos.31771471 and 32172583).
摘要Because of their great therapeutic and economic value,medicinal plants have attracted increasing scientific attention.With the rapid development of high-throughput sequencing technology,the genomes of many medicinal plants have been sequenced.Storing and analyzing the increasing volume of genomic data has become an urgent task.To solve this challenge,we have proposed the Traditional ChineseMedicine Plant Genome database(TCMPG,http://gffzz550319536f6144ach6q5xowovvxkf65n5.ffgz.tsg.suse.edu.cn/TCMPG/),an integrative database for storing the scattered genomes of medicinal plants.TCMPG currently includes 160 medicinal plants,195 corresponding genomes,and 255 herbal medicines.Detailed information on plant species,genomes,and herbal medicines is also integrated into TCMPG.Popular genomic analysis tools are embedded in TCMPG to facilitate the systematic analysis of medicinal plants.These include BLAST for identifying orthologs from different plants,SSR Finder for identifying simple sequence repeats,JBrowse for browsing genomes,Synteny Viewer for displaying syntenic blocks between two genomes,and HmmSearch for identifying protein domains.TCMPG will be continuously updated by integrating new data and tools for comparative and functional genomic analysis.
基金Supported by the National Natural Science Foundation of China(51501038,51731004,51671054)the Fundamental Research Funds for the Central Universities(3212007203)
摘要The feasibility of employing shell powder as a novel bio-filler to prepare fluorocarbon coating is demonstrated.According to the relevant Chinese standards, the thermal and mechanical properties of the shell powder-filled fluorocarbon coating were evaluated, and compared with those filled by commercial calcium carbonate. All the shell powder-filled coatings can meet the requirements stated in the relevant standards, and with decreasing the particle size of the shell powders, the performance of the thermal insulation coating is enhanced. The coating(SC3) filled by shell powders with an average particle size of 2.81 μm possesses a better thermal insulation performance than the coating(CC) filled by commercial calcium carbonate. The coating SC3 has comparable adhesive force and washing resistance with the coating CC, and in the washing resistance test, after 2000 cycles, the coating SC3 was still able to cover totally their substrates. This work demonstrates a high value-added disposal method for the aquacultural wastes.
摘要Waste shell stacking with odor and toxicity is a serious hazard to our living environment. To make effective use of the natural resources, the shell powder was applied as a filler of outdoor thermal insulation coatings. Sodium stearate(SS) was used to modify the properties of shell powder to reduce its agglomeration and to increase its compatibility with the emulsion. The oil absorption rate and the spectrum reflectance of the shell powder show that the optimized content of SS as a modifier is 1.5wt%. The total spectrum reflectance of the coating made with the shell powder that is modified at this optimum SS content is 9.33% higher than that without any modification. At the optimum SS content of 1.5wt%, the thermal insulation of the coatings is improved by 1.0℃ for the cement mortar board and 1.6℃ for the steel plate, respectively. The scouring resistance of the coating with the 1.5wt% SS-modified shell powder is three times that of the coating without modification.
摘要Despite the high prevalence of straight back syndrome(SBS),there is still limited research on this condition,posing challenges for effective diagnosis and treatment.The disease has been known for a long time,but there have been few related studies,which mostly consist of case reports.These studies have not been systematically summarized,making it difficult to meet the current needs of diagnosis and treatment.This article summarized the existing literature and comprehensively reviewed the diagnosis,pathogenesis,treatment,and research status of mitral valve prolapse related to SBS.We specifically emphasized the mechanisms and prognosis of SBS combined with mitral valve prolapse and discussed the latest research progress in this disease.
基金Project supported by the National Natural Science Foundation of China(Grant No.11904117)the IndustryUniversity-Research Collaboration Project of Jiangsu Province,China(Grant No.BY2019058)+1 种基金the Scientific Research Foundation of Huaiyin Institute of Technology(Grant No.Z301B19529)the Training Foundation of Postgraduate Supervisor(Grant No.Z206E20555)。
摘要Rotational manipulation of massive particles and biolo gical samples is essential for the development of miniaturized lab-on-a-chip platforms in the fields of chemical,medical,and biological applications.In this paper,a device concept of a two-dimensional acoustofluidic chamber actuated by multiple nonlinear vibration sources is proposed.The functional chamber enables the generation of acoustic streaming vortices for potential applications that include strong mixing of multiphase flows and rotational manipulation of micro-ano-scale objects without any rotating component.Using numerical simulations,we find that diversified acoustofluidic fields can be generated in the chamber under various actuations,and massive polystyrene beads inside can experience different acoustophoretic motions under the combined effect of an acoustic radiation force and acoustic streaming.Moreover,we investigate and clarify the effects of structural design on modulation of the acoustofluidic fields in the chamber.We believe the presented study could not only provide a promising potential tool for rotational acoustofluidic manipulation,but could also bring this community some useful design insights into the achievement of desired acoustofluidic fields for assorted microfluidic applications.
基金grants from the Key Sci-Tech Research Foundationof Guangzhou City(No.2002XZ-J200131)Natural Science Foundationof Guangdong Province(No.031563)National Natural ScienceFoundation(No.10675175).
摘要Objective:To calculate the focus absorption dose of 153Sm-EDTMP with the Monte Carlo(MC)EGS4 method for treatment of bone metastases from nasopharyngeal carcinoma or breast cancer,and investigate the relationship between the focus absorption dose and painkilling effect of 153Sm-EDTMP.Methods:Four patients with multiple bone metastases from nasopharyngeal or breast carcinoma and suffered from grade IV bone pain were treated with radionuclide internal irradiation of 153Sm-EDTMP.The absorption dose and dose distribution of bone metastases and other targeted organs were calculated with MC EGS4 program based on the time-order SPECT/CT scanning and the measurement of the radioactivity in the urine accumulation.The release of bone pain and the improvement of life quality were observed.Results:Bone pain of the patients was significantly alleviated to grade II for 3–4 weeks after internal 153Sm-EDTMP irradiation.The 3-dimensional absorption dose distribution image of bone metastases and targeted organs showed that the dose distribution in bone metastases was not asymmetrical.After injection of 0.65×37 MBq/kg 153Sm-EDTMP,the highest absorption dose in bone lesions was about 4.9–5.9 Gy,and the dose in the lesion margin was about 2.0 Gy.Using the highest dose as reference dose point,the relative absorption dose values of bone marrow,vertebra and sex organ near lesions were 0.48–1.1 Gy,0.51–0.85 Gy,and 0.01–0.14 Gy,respectively.Conclusion:The absorption dose of bone metastases is significantly lower than treatment dose of 30 Gy after single irradiation of 153Sm-EDTMP.The painkilling effect is limited and in accordance with clinical observation.
基金National Natural Science Foundation of China(No.20372049)Application Basic Research Funding of SichuanAnalytical&Testing Center of Sichuan University for support in NMR and MS analyses
摘要A practical protocol to obtain 1,1′-binaphthyl-2,2′-diamine was developed from 2-naphthol and 2-naphthylhydrazine under mild conditions:solvent-free,125-130℃,atmospheric pressure.The convenient procedure makes the process amenable for large-scale synthesis of the versatile compound.
摘要Several studies have largely focused on the significant role of the nervous and immune systems in the process of tumorigenesis, including tumor growth, proliferation, apoptosis, and metastasis. The brain-gut-axis is a new paradigm in neuroscience, which describes the biochemical signaling between the gastrointestinal (GI) tract and the central nervous system. This axis may play a critical role in the tumorigenesis and development of GI cancers. Mechanistically, the bidirectional signal transmission of the brain-gut-axis is complex and remains to be elucidated. In this article, we review the current findings concerning the relationship between the brain-gut axis and GI cancer cells, focusing on the significant role of the brain-gut axis in the processes of tumor proliferation, invasion, apoptosis, autophagy, and metastasis. It appears that the brain might modulate GI cancer by two pathways: the anatomical nerve pathway and the neuroendocrine route. The simulation and inactivation of the central nervous, sympathetic, and parasympathetic nervous systems, or changes in the innervation of the GI tract might contribute to a higher incidence of GI cancers. In addition, neurotransmitters and neurotrophic factors can produce stimulatory or inhibitory effects in the progression of GI cancers. Insights into these mechanisms may lead to the discovery of potential prognostic and therapeutic targets.
摘要Soil texture is an indicator of soil physical structure which delivers many ecological functions of soils such as thermal regime, plant growth, and soil quality. However, traditional methods for soil texture measurement are time-consuming and labor-intensive. This study attempts to explore an indirect method for rapid estimating the texture of three subgroups of purple soils (i.e. calcareous, neutral, and acidic). 190 topsoil (0 - 10 cm) samples were collected from sloping croplands in Tongnan and Beibei Districts of Chongqing Municipality in China. Vis-NIR spectrum was measured and processed, and stepwise multiple linear regression (SMLR), partial least squares regression (PLSR), and back propagation neural network (BPNN) models were constructed to inform the soil texture. The clay fractions ranged from 4.40% to 27.12% while sand fractions ranged from 0.34% to 36.57%, hereby soil samples encompass three textural classes (i.e. silt, silt loam, and silty clay loam). For the original spectrum, the texture of calcareous and neutral purple soils was not significantly correlated with spectral reflectance and linear models (SMLR and PLSR) exhibited low prediction accuracy. The correlation coefficients and the goodness-of-fits between soil texture and the transformed spectra of all soil groups increased by continuum-removal (CR), first-order differential (R'), and second-order differential (R") transformations. Among them, the R" had the best performance in terms of improving the correlation coefficients and the goodness-of-fits. For the calcareous purple soil, the SMLR exceeds PLSR and BPNN with a higher coefficient of determination (R2) and the ratio of performance to inter-quartile distance (RPIQ) values and lower root mean square error of validation (RMSEV), but for the neutral and acidic purple soils, the PLSR model has a better prediction accuracy. In summary, the linear methods (SMLR and PLSR) are more reliable in estimating the texture of the three purple soil groups when using Vis-NIR spectroscopy inversion.
基金supported by the National Natural Science Foundation of China(52172239)Project of State Key Laboratory of Environment-Friendly Energy Materials(SWUST,Grant Nos.22fksy23 and 18ZD320304)+3 种基金the Frontier Project of Chengdu Tianfu New Area Institute(SWUST,Grand No.2022ZY017)Chongqing Talents:Exceptional Young Talents Project(Grant No.CQYC201905041)Natural Science Foundation of Chongqing China(Grant No.cstc2021jcyj-jqX0031)Interdiscipline Team Project under auspices of“Light of West”Program in Chinese Academy of Sciences(Grant No.xbzg-zdsys-202106).
摘要Rechargeable magnesium-ion(Mg-ion)batteries have attracted wide attention for energy storage.However,magnesium anode is still limited by the irreversible Mg plating/stripping procedure.Herein,a well-designed binary Bi2O3-Bi2S3(BO-BS)heterostructure is fulfilled by virtue of the cooperative interface and energy band engineering targeted fast Mg-ion storage.The built-in electronic field resulting from the asymmetrical electron distribution at the interface of electron-rich S center at Bi2S3 side and electron-poor O center at Bi2O3 side effectively accelerates the electrochemical reaction kinetics in the Mg-ion battery system.Moreover,the as-designed heterogenous interface also benefits to maintaining the electrode integrity.With these advantages,the BO-BS electrode displays a remarkable capacity of 150.36 mAh g−1 at 0.67 A g-1 and a superior cycling stability.This investigation would offer novel insights into the rational design of functional heterogenous electrode materials targeted the fast reaction kinetics for energy storage systems.
基金supported by the Knowledge Innovation Program of the Chinese Academy of Sciences (No.KSCX2-YW-G-052)
摘要Tribenuron methyl (TBM) is a member of the sulfonylurea herbicide family and is widely used worldwide. In this study, TBM- degrading bacteria were enriched with TBM as potential carbon, nitrogen or sulfur source, and 44 bacterial isolates were obtained. These isolates were phylogenetically diverse, and were grouped into 25 operational taxonomic units and 14 currently known genera. Three representatives, Bacillus sp. strain BS2, Microbacterium sp. strain BS3, and Cellulosimicrobium sp. strain BSI 1, were selected, and their growth and TBM removal from culture broth were investigated. In addition, indigenous earthworms were collected and applied to augment TBM degradation in lab-scale soil column experiments. Results demonstrated that Bacillus sp. strain BS2 and earthworms significantly increased TBM removal during soil column experiments.
基金financially supported by the Program for New Century Excellent Talents in Universitiesthe National Natural Science Foundation of China (Nos. 21074088, 31201426)
摘要Multiarm star block copolymers hyperbranched polyethylenimine-b-poly(2-hydroxyethyl methacrylate) (HPEI-b- PHEMA) with average 28 PHEMA arms have been prepared by atom transfer radical polymerization (ATRP) of HEMA in a mixed solvent of methanol and water using a core-first strategy. The hyperbranched macroinitiator employed was prepared on the basis of well-defined hyperbranched polyethylenimine with Mw/Mn of 1.04 by amidation with 2-bromo-isobutyryl bromide. The polymerization condition was optimized to prepare star copolymers with narrow dispersity, and the variables included the volume ratio of methanol to water, the molar ratio of initiating site to CuC1 and the molar ratio of [CuCl]:[CuBr2]. Under the optimized polymerization condition, the lowest Mw/Mn value of the obtained star copolymers was around 1.3. Kinetic analysis showed that an induction period existed in the polymerization of HEMA. After this induction period, a linear dependence of ln([M]0/[M]t) on time was observed. The obtained HPEI-b-PHEMA could adsorb hydrophilic molecules. The comparison with the star copolymer with hydrophobic core and hydrophilic PHEMA shell verified that both the hydrophilic core and shell could host the hydrophilic guests, but the amidated HPEI core was more effective than the PHEMA shell.
基金supported by the applied technology research and development program"Study on Chinese medicine preparation for prevention of New Coronavirus"in Heilongjiang Province.(GA20C005)。
摘要Patients with novel coronavirus disease-19(COVID-19)pneumonia continue to have problems with respiratory function,physical and psychological function,the ability to perform activities of daily living,and social participation after discharge from the hospital.As such,strengthening rehabilitation treatments for discharged patients and relapse prevention after recovery are important aspects of the prevention and control of COVID-19.This paper combined the principles and practices of in Chinese and Western medicine and compiled the recommendations of both for home rehabilitation in the post-COVID-19 epidemic stage.The purpose of this paper is to facilitate the self-rehabilitation of patients with COVID-19 and to promote the prevention and control of COVID-19 at this current stage.
基金National Key R&D Program of China(No.2019YFC1709001,2022YFC3500703)Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine.(No.ZYYCXTD-D-202003)+1 种基金Fund of Science and Technology Department of Sichuan Province,China(No.2021ZYD0081,2022ZDZX0033)Xinglin Youth Innovation Team Project of Chengdu University of Traditional Chinese Medicine(QNTD2022003).
摘要本文介绍了名为ACU&MOX-DATA(Acupuncture&moxibustion-deep analysis to treat accurately)的针灸多组学异源数据融合分析网络平台(http://gffzz550319536f6144ach6q5xowovvxkf65n5.ffgz.tsg.suse.edu.cn/ACU&MOX-DATA/)。该平台旨在整合分析针灸相关疾病、临床和实验室获得的异源、多层次数据,其典型特点是在中医理论指导下,收集针灸研究所获得的各种观测指标,通过异源、多层次数据融合分析的方法,实现对针灸学领域关键科学问题的集成分析和可视化解读。本文介绍了该平台目前已有的功能及未来的研究计划。
摘要Objectives:This paper aims to explore application effect of the dual-perspective care mode for safety and comfort needs in patients with magnetic resonance imaging(MRI)examination.Methods:A total of 132 patients with MRI examination who were admitted to our hospital from September 2018 to February 2020 were selected as the research objects,and they were divided into control group and intervention group by random number table method,with 66 cases in each group.Patients in the control group received routine nursing care,while patients in the intervention group received the dual-perspective nursing care.The psychological state,nursing safety quality,nursing satisfaction,and quality of life scores of the two groups were compared and analyzed.Results:The Self-Rating Anxiety Scale(SAS)(32.05±2.63)and Self-Rating Depression Scale(SDS)(33.14±4.15)of patients in the intervention group receiving dual-perspective nursing mode were lower than those in the control group,and the improvement level of psychological states such as anxiety and depression was significantly better than that in the control group,the difference was statistically significant(P<0.05).Intervention group patients in early treatment of dangerous situation(3.26±1.08),implementation of safety measures(3.32±1.15),prevention of accidental injury(3.17±0.95),and other eight nursing safety quality index scores were higher than the control group(P<0.05).The nursing satisfaction of patients in the intervention group(93.94%)was significantly higher than that in the control group(75.76%),and the differences were statistically significant(P<0.05).In addition,the five life quality indexes of the intervention group were higher than those of the control group,including physiological(90.51±6.39),psychological(91.33±5.76),and emotional(90.45±5.39).Conclusion:The dual-perspective nursing intervention for the safety and comfort needs of patients with MRI examination can effectively improve the anxiety and depression in the diagnosis and treatment,ensure the safety and comfort of the examination process,improve patients'satisfaction with nursing,so as to ensure the effectiveness and accuracy of the examination results,which has great clinical application value.
摘要Diabetic foot ulcers are a prevalent complication that can significantly impact quality of life and necessitate high-level amputations. Hence, early diagnosis and treatment, elucidation of pathogenesis, and targeted countermeasures assume paramount importance. Wound healing entails a complex process wherein various components such as inflammatory cells, extracellular matrix, and immune cells intricately interact with each other. Due to the vulnerability of the skin to damage, inadequate or impaired wound healing has emerged as an urgent clinical challenge requiring resolution. This paper provides a comprehensive overview of the pathogenesis, diagnosis, and treatment of diabetic foot ulcers in order to offer theoretical guidance for specific interventions.