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Single-time fertilization with controlled release blended fertilizer optimizes soil nitrogen distribution and root characteristics to increase conventional japonica rice(Oryza sativa L.)grain yield and nitrogen use efficiency 认领 引用 被引量：2
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作者 Yuhui Wang Jie Sun +13 位作者 Shen Gao Bin He Zhengyang Wu Wenjun He Weike Tao Xin’ao Tang Zhi Geng Weiwei Li Fei Yang Zhengrong Jiang Zhenghui Liu Yanfeng Ding Soulaiman Sakr Ganghua Li 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2026年第7期2771-2782,共12页
Single-time fertilization(STF)with controlled release blended fertilizer(CRBF)improves grain yield and nitrogen use efficiency(NUE)in rice production.However,the impact of soil nitrogen(N)distribution and root growth ... Single-time fertilization(STF)with controlled release blended fertilizer(CRBF)improves grain yield and nitrogen use efficiency(NUE)in rice production.However,the impact of soil nitrogen(N)distribution and root growth on rice yield and NUE under STF with CRBF remains unclear.Here,a two-year field experiment investigated the effects of two fertilizer types(normal urea(U)and CRBF)and two single-time fertilization methods(broadcast and side-deep fertilization)on the soil N distribution,plant N uptake,root characteristics,grain yield,and NUE.The results showed that CRBF under STF increased the averages of plant dry matter accumulation,N uptake,grain yield,nitrogen recovery efficiency(NRE),and nitrogen agronomic efficiency(NAE)by 8.29,21.85,10.57,79.28,and 74.8%compared to the other treatments,respectively.Side-deep fertilization with CRBF further increased NUE by 12.78%compared to broadcast.Moreover,CRBF under STF increased the leaf SPAD value and glutamine synthetase(GS)/glutamine oxoglutarate aminotransferase(GOGAT)activity by 5.93 and 25.58%,respectively.CRBF under STF increased the soil inorganic N concentration and showed a“rising early and stabilizing later”pattern.In addition,CRBF under STF improved rice root growth and increased the averages of root biomass,total root number,root average diameter,total root length,total root surface area,and total root volume by 28.30,28.56,18.64,13.38,35.26,and 37.06%,respectively,at the tillering and heading stages.Partial least squares path modeling indicated that CRBF under STF increased the soil inorganic N concentration which improved root morphology,thereby increasing N uptake and improving the rice yield and NUE.Taken together,our findings show that CRBF with single-time fertilization is the preferred N fertilizer strategy for achieving high yield and efficiency in rice,and that side-deep fertilization is the optimal fertilization method. 展开更多
关键词 yield nitrogen use efficiency controlled release blended fertilizer soil nitrogen distribution root
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One-time application of controlled-release blended fertilizer increases rice yield and nitrogen utilization by optimizing root morphological trait distribution and nitrogen uptake 认领 引用 被引量：5
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作者 Yuhui Wang Shen Gao +13 位作者 Jie Sun Bin He Wenjun He Weike Tao Xin'ao Tang Zhi Geng Zhengyang Wu Weiwei Li Zhengrong Jiang Zhenghui Liu Yanfeng Ding Soulaiman Sakr Pengfu Hou Ganghua Li 《The Crop Journal》 SCIE CAS CSCD 2025年第4期1234-1245,共12页
One-time application of controlled-release blended fertilizer(CRBF,a mixture of five nitrogen(N)fertilizers in a certain ratio)can achieve high yield and N use efficiency(NUE)in rice(Oryza sativa L.).However,the effec... One-time application of controlled-release blended fertilizer(CRBF,a mixture of five nitrogen(N)fertilizers in a certain ratio)can achieve high yield and N use efficiency(NUE)in rice(Oryza sativa L.).However,the effects of CRBF with one-time application on root spatial distribution and physiological characteristics remain unclear.We measured the effects of CRBF with one-time application on rice yield,NUE,root morphology and growth,and N uptake capacity in field and root box experiments.Six N treatments were set up:no nitrogen(N0),high-yield three-split application of urea as a control(CK),urea(U)with broadcast,U with side-deep fertilization,CRBF with broadcast,and CRBF with side-deep fertilization.Our findings showed that root characters were positively correlated with yield and NUE.Compared to CK and U treatments,CRBF with one-time applications increased root characters(including root biomass,root N uptake,root activity,and the expression level of ammonium transporters)at tillering and heading stages.The root length,surface area and volume in the 0-10 cm soil layer enhanced under CRBF with one-time applications at tillering stage,and in the 0-20 cm soil layer at the heading stage.This contributed a5.96%-39.40% and 3.69%-16.87% increase in plant dry matter accumulation and N uptake,and a2.08%-18.28% and 14.60%-149.57% increase in yield and NUE,in 2022 and 2023,respectively.Taken together,our findings showed that one-time application of CRBF could increase rice yield and NUE by optimizing the root morphology distribution and N uptake. 展开更多
关键词 Rice(Oryza sativa L.) Controlled release blended fertilizer Root Yield Nitrogen utilization
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Association between ABO Blood Types and the Risk of Gestational Diabetes Mellitus:A Prospective Cohort Study 认领 引用 被引量：1
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作者 Shuanghua Xie Shuangying Li +8 位作者 Shaofei Su Enjie Zhang Shen Gao Yue Zhang Jianhui Liu Minhui Hu Ruixia Liu Wentao Yue Chenghong Yin 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2025年第6期678-692,共15页
Objective To investigate the association between ABO blood types and gestational diabetes mellitus(GDM)risk.Methods A prospective birth cohort study was conducted.ABO blood types were determined using the slide method... Objective To investigate the association between ABO blood types and gestational diabetes mellitus(GDM)risk.Methods A prospective birth cohort study was conducted.ABO blood types were determined using the slide method.GDM diagnosis was based on a 75-g,2-h oral glucose tolerance test(OGTT)according to the criteria of the International Association of Diabetes and Pregnancy Study Groups.Logistic regression was applied to calculate the odds ratios(ORs)and 95%confidence intervals(CIs)between ABO blood types and GDM risk.Results A total of 30,740 pregnant women with a mean age of 31.81 years were enrolled in this study.The ABO blood types distribution was:type O(30.99%),type A(26.58%),type B(32.20%),and type AB(10.23%).GDM was identified in 14.44%of participants.Using blood type O as a reference,GDM risk was not significantly higher for types A(OR=1.05)or B(OR=1.04).However,women with type AB had a 19%increased risk of GDM(OR=1.19,95%CI=1.05–1.34;P<0.05),even after adjusting for various factors.This increased risk for type AB was consistent across subgroup and sensitivity analyses.Conclusion The ABO blood types may influence GDM risk,with type AB associated with a higher risk.Incorporating it—either as a single risk factor or in combination with other known factors—could help identify individuals at risk for GDM before or during early pregnancy. 展开更多
关键词 ABO blood type phenotype Cohort study Risk factors Gestational diabetes mellitus
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Geochronology and Geochemistry of Permian Dashizhai Basin in Xing'an-Inner Mongolia Orogen:Implications for the Evolution of the Paleo-Asian Ocean 认领 引用
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作者 Chi Zhang Guosheng Wang +4 位作者 Zhiguang Zhou Shen Gao Neng Zhang Liudong Wang Erqiang Bai 《Journal of Earth Science》 SCIE CAS CSCD 2025年第4期1444-1464,共21页
The Xing'an-Inner Mongolia Orogen is a critical tectonic unit for constraining the evolution of the Paleo-Asian Ocean.However,the location and time of the closure of the Paleo-Asian Ocean are still debated.Here,we... The Xing'an-Inner Mongolia Orogen is a critical tectonic unit for constraining the evolution of the Paleo-Asian Ocean.However,the location and time of the closure of the Paleo-Asian Ocean are still debated.Here,we select a representative basin in Dashizhai in northeastern China,using U-Pb zircon geochronology and geochemistry to analyze the sedimentary facies,depositional ages,and provenance.The results show that the ages of the Dashizhai Formation range from 400 to 347 Ma,the Shoushangou Formation range from 400 to 348 Ma,the Zhesi Formation range from 307 to 252 Ma,and the Linxi Formation range from 299 to 241 Ma.The Dashizhai Formation is composed of metamorphic andesite and clastic rocks.The Shoushangou Formation comprises siltstone,rhyolite,and argillaceous siltstone.The Zhesi and Linxi Formations are composed of mudstone and argillaceous siltstone.Geochemical data shows that these rocks are enriched in light rare earth elements and depleted in Eu with various La/Sc,Th/Sc,and La/Co ratios.The Permian Dashizhai Basin is from Permian volcanic and felsic igneous rocks from the Ergun,Xing'an,and Songliao blocks.The absence of the Late Carboniferous strata in the Dashizhai Basin indicates an extension setting during this period.Furthermore,we suggest the Xing'an-Inner Mongolia Orogen was an uplifting process associated with evolution the Paleo-Asian Ocean during the Late Permian. 展开更多
关键词 zircon U-Pb age geochemistry Permian basin Xing'an-Inner Mongolia Orogen Paleo-Asian Ocean depositional provenance
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Optimizing rice yield:Evaluating the nitrogen supply characteristics of slow-and controlled-release fertilizers using the leaf nitrogen balance index 认领 引用
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作者 Weike Tao Qiuli Chen +6 位作者 Weiwei Li Shen Gao Jiaqi Li Yuhui Wang Sajjad Ahmad Yanfeng Ding Ganghua Li 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2025年第11期4182-4194,共13页
Synchronizing the nitrogen(N)supply of slow-and controlled-release N fertilizers(SCRNFs)with rice N demand is essential in replacing multiple urea applications with a single basal application of SCRNFs.Traditional ass... Synchronizing the nitrogen(N)supply of slow-and controlled-release N fertilizers(SCRNFs)with rice N demand is essential in replacing multiple urea applications with a single basal application of SCRNFs.Traditional assessment of N supply characteristics primarily examines N release patterns,which are limited to coated SCRNFs and disregard N transformation mechanisms,necessitating a more universal and reliable index.Based on the capacity of crop N status to detect N deficiency or excess,we hypothesized that utilizing leaf N balance index(NBI)as a measure of N status could offer novel insights into assessing N supply characteristics of SCRNFs.Field experiments were conducted with four individual SCRNFs-humic acid urea(HAU),sulfur-coated urea(SCU),urease inhibitor urea(UIU),and polymer-coated urea(PCU)and their four combined forms,alongside high-yield urea split application as control(CK).The results revealed that NBI dynamics relative to CK reflected the N supply potential of different SCRNFs while categorizing them as short-,medium-,and long-acting fertilizers.Combinations incorporating the long-acting SCRNF(PCU)consistently demonstrated superior performance in yield(by 5.5%)and N use efficiency(by 42.8%)through providing more consistent and efficient N supply throughout the rice growth cycle.Grain yield exhibited negative correlation with the difference in NBI dynamics between SCRNFs and CK,suggesting that synchronizing N supply between one-time application of SCRNFs and conventional high-yield fertilization is crucial for high yield.These findings demonstrate the potential of N status diagnosed by leaf NBI to evaluate N supply characteristics of SCRNFs and highlight the importance of synchronized N supply for a one-time SCRNF application. 展开更多
关键词 rice slow-and controlled-release fertilizer nitrogen balance index nitrogen supply yield
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Optimizing rice productivity using controlled-release blended fertilizers in the Yangtze River Delta of China 认领 引用
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作者 Shen Gao Zhuoshu Liu +10 位作者 Yuhui Wang Weike Tao Zihao Wang Jie Sun Hao Wu Jianwei Zhang Haoyu Qian Yu Jiang Zhenghui Liu Yanfeng Ding Ganghua Li 《The Crop Journal》 SCIE CAS CSCD 2025年第6期1898-1907,共10页
Rice productivity faces critical sustainability challenges from stagnating yields and inefficient fertilizer use,particularly in intensive agricultural regions like the Yangtze River Delta(YRD)of China.Controlled-rele... Rice productivity faces critical sustainability challenges from stagnating yields and inefficient fertilizer use,particularly in intensive agricultural regions like the Yangtze River Delta(YRD)of China.Controlled-release blended fertilizers(CRBF),which synchronize nutrient release with crop demand,represent a promising strategy to enhance rice productivity.Here,we conducted an eight-year(2017–2024)field study across 25 representative sites in the YRD to evaluate CRBF’s effects,complemented by a regional extrapolation analysis.Our findings showed that,relative to conventional fertilization,CRBF increased rice yield by 4.9%,primarily by increasing the number of effective panicles(5%)and plant biomass(5.2%–11.3%).Notably,this yield benefit rose to 5.3%when CRBF was applied via deep placement,which was attributed to greater root biomass(13.1%–29.2%)and higher soil NH4+-N availability(24.3%–43.6%),thereby enhancing N uptake.Furthermore,initial soil organic matter was identified as the predominant modulator of CRBF effectiveness.Regional extrapolation projected that applying CRBF could enhance rice yield by 4.0%across the YRD,with deep placement providing an additional 2.1%gain.In conclusion,our study demonstrates that adopting CRBF,particularly with deep placement,is a robust and effective strategy to sustainably boost rice productivity in intensive rice cultivation systems. 展开更多
关键词 Multi-site trial Controlled-release blended fertilizer Deep placement Rice yield Soil organic matter
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Harmonized technical standard test methods for quality evaluation of medical fluorescence endoscopic imaging systems 认领 引用
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作者 Bodong Liu Zhaojun Guo +6 位作者 Pengfei Yang Jian’an Ye Kunshan He Shen Gao Chongwei Chi Yu An Jie Tian 《Visual Computing for Industry,Biomedicine,and Art》 EI 2025年第1期28-41,共14页
Fluorescence endoscopy technology utilizes a light source of a specific wavelength to excite the fluorescence signals of biological tissues.This capability is extremely valuable for the early detection and precise dia... Fluorescence endoscopy technology utilizes a light source of a specific wavelength to excite the fluorescence signals of biological tissues.This capability is extremely valuable for the early detection and precise diagnosis of pathological changes.Identifying a suitable experimental approach and metric for objectively and quantitatively assessing the imaging quality of fluorescence endoscopy is imperative to enhance the image evaluation criteria of fluorescence imaging technology.In this study,we propose a new set of standards for fluorescence endoscopy technology to evaluate the optical performance and image quality of fluorescence imaging objectively and quantitatively.This comprehensive set of standards encompasses fluorescence test models and imaging quality assessment protocols to ensure that the performance of fluorescence endoscopy systems meets the required standards.In addition,it aims to enhance the accuracy and uniformity of the results by standardizing testing procedures.The formulation of pivotal metrics and testing methodologies is anticipated to facilitate direct quantitative comparisons of the performance of fluorescence endoscopy devices.This advancement is expected to foster the harmonization of clinical and preclinical evaluations using fluorescence endoscopy imaging systems,thereby improving diagnostic precision and efficiency. 展开更多
关键词 Fluorescence endoscopy Near-infrared Image evaluation Standardization
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医用钬激光设备注册申报资料要求探讨 认领 引用
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作者 申高 刘柏东 《中国药物警戒》 2025年第11期1263-1266,共4页
目的总结医用钬激光设备注册申报中适用范围界定、量效关系研究及动物试验研究的标准与要求,为注册申请人提供参考。方法分析美国食品药品监督管理局(FDA)和我国国家药品监督管理局(NMPA)的相关指导原则与要求,提炼其核心监管要点。结... 目的总结医用钬激光设备注册申报中适用范围界定、量效关系研究及动物试验研究的标准与要求,为注册申请人提供参考。方法分析美国食品药品监督管理局(FDA)和我国国家药品监督管理局(NMPA)的相关指导原则与要求,提炼其核心监管要点。结果建立了科学规范的适用范围表述框架,明确了量效关系研究的内容、方法与数据处理要求,系统归纳了动物试验研究的类型、目的及实施要点。提升了申报资料质量与审评效率。结论医用钬激光设备注册申报需以临床需求为导向、科学数据为支撑,严格落实层级化、量化与规范化要求。注册申请人应充分参考并适配FDA与NMPA在资料要求上的差异,聚焦核心监管要求,为产品安全有效性提供充分证据,保障产品顺利上市。 展开更多
关键词 医用钬激光设备 注册申报 适用范围 量效关系 动物试验 监管要求
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Subsurface banding of blended controlled-release urea can optimize rice yields while minimizing yield-scaled greenhouse gas emissions 认领 引用 被引量：14
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作者 Weiwei Li Sajjad Ahmad +8 位作者 Dun Liu Shen Gao Yuhui Wang Weike Tao Lin Chen Zhenghui Liu Yu Jiang Ganghua Li Yanfeng Ding 《The Crop Journal》 SCIE CSCD 2023年第3期914-921,共8页
Controlled-release urea(CRU)is widely reported to supply crop nitrogen(N)demand with one basal application,thus effectively replacing split applications of urea without diminishing grain yield and N use efficiency(NUE... Controlled-release urea(CRU)is widely reported to supply crop nitrogen(N)demand with one basal application,thus effectively replacing split applications of urea without diminishing grain yield and N use efficiency(NUE).However,its use for replacement for high-yield split applications of urea(CK)for rice is untested.In addition,the degree to which greenhouse gas(GHG)emissions in rice systems are affected when CRU is substituted for CK remains unclear.During 2017 and 2018,we sampled plant growth and gas emissions in a rice paddy field treated with three CRU types(sulfur-coated urea[SCU],polymer-coated urea[PCU],and bulk blended CRU[BBU])applied via two methods(surface broadcasting on the soil and subsurface banding at 5 cm depth),with CK as a control.The three CRUs led to different soil NH4+-N dynamics,and the N supply pattern under BBU was more beneficial for rice seedling establishment than under SCU and PCU,resulting in grain yield and NUE comparable to those under CK.CRU type showed no significant effect on either CH4 emissions or N2O emissions,and broadcast CRUs exhibited significantly higher total GHG emissions than CK.However,banded CRUs significantly reduced the total GHG emissions in comparison with broadcast CRUs,by 9.2%averaged across the two years.Reduced CH4 emissions,particularly during the period prior to the middle drainage,contributed largely to the GHG difference.With comparably high grain yield and low total GHG emissions,banded BBU showed a low yield-scaled GHG(GHG emissions divided by grain yield)comparable to that under CK in both years.Overall,our study suggested that N management synchronized with rice demand and contributing to a high NUE tended to minimize yield-scaled GHG.Broadcast CRU can hardly substitute for CK in terms of either grain yield or GHG emissions,but banded BBU is a promising N management strategy for sustaining rice production while minimizing environmental impacts. 展开更多
关键词 Controlled-release fertilizer N subsurface placement CH4 N2O Yield
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基于改进深度学习的食品外包装缺陷在线智能检测方法 认领 引用 被引量：1
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作者 申高 王子剑 +1 位作者 王晓峰 李瑞文 《食品与机械》 CAS CSCD 北大核心 2025年第12期236-244,共9页
[目的]针对目前食品生产线外包装缺陷检测中人工检测效率低、漏检误检率高,以及传统机器视觉算法对复杂纹理包装、微小缺陷识别能力不足的问题,提出一种兼顾检测精度与速度的智能化检测方法。[方法]以Swin Transformer为核心特征提取模... [目的]针对目前食品生产线外包装缺陷检测中人工检测效率低、漏检误检率高,以及传统机器视觉算法对复杂纹理包装、微小缺陷识别能力不足的问题,提出一种兼顾检测精度与速度的智能化检测方法。[方法]以Swin Transformer为核心特征提取模块,利用其对图像全局信息的建模能力和多尺度特征融合优势,精准捕捉外包装表面的微小褶皱、印刷偏移等缺陷特征。同时引入YOLOv12的快速检测框架,通过优化颈部网络与损失函数,实现缺陷区域的快速定位与分类,形成高精度特征提取—快速目标检测的一体化检测流程。[结果]该方法对常见缺陷类型的平均检测精度均值>96.50%,较优化前方法提升超过10.00%。单张图像检测耗时<10 ms,满足生产线每秒30帧的实时检测要求。此外,在不同食品检测中,该方法仍保持稳定性能,鲁棒性显著优于对比方法。[结论]通过融合Swin Transformer特征提取优势与YOLOv12快速检测能力,解决了食品外包装缺陷检测中精度与速度难以兼顾的核心问题。 展开更多
关键词 食品生产线 外包装缺陷检测 Swin Transformer YOLOv12 兼顾检测精度与速度
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All-solid-state ultraviolet laser based on frequency doubling in an external ring cavity 认领 引用
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作者 SHEN Gao WANG Bao-shan +3 位作者 TAN Hui-ming PENG Ji-ying FU Xi-hong ZHAO Yu-huan 《Optoelectronics Letters》 2007年第6期448-450,共3页
An all-solid-state ultraviolet laser based on frequency doubling in an external ring cavity with low input pump power is reported. Both second harmonic generation （SHG） and fourth harmonic generation （PRIG） occurr... An all-solid-state ultraviolet laser based on frequency doubling in an external ring cavity with low input pump power is reported. Both second harmonic generation （SHG） and fourth harmonic generation （PRIG） occurred in an external threemirrors ring cavity. The need for impedance matching of this cavity to the input radiation was eliminated and the cavity adaptation was simplified, because the mirrors were not highly reflecting at 1064 nm and the cavity resonates only at 532 rim. Experiment results demonstrate that the conversion efficiency of this external cavity is higher than that of the singlepass condition. 展开更多
关键词 固体 激光器 外部环空腔 频率重叠
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Mechanism analysis of radiation generated by the beam-plasma interaction in a vacuum diode 认领 引用
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作者 Zengchao JI Shixiu CHEN Shen GAO 《Plasma Science and Technology》 SCIE EI CAS CSCD 2017年第1期20-28,共9页
When we were studying the vacuum switch,we found that the vacuum diode can radiate a broadband microwave.The vacuum diode is comprised of a cathode with a trigger device and planar anode,there is not a metallic bellow... When we were studying the vacuum switch,we found that the vacuum diode can radiate a broadband microwave.The vacuum diode is comprised of a cathode with a trigger device and planar anode,there is not a metallic bellows waveguide structure in this device,so the radiation mechanism of the vacuum diode is different from the plasma filled microwave device.It is hard to completely imitate the theory of the plasma filled microwave device.This paper analyzes the breakdown process of the vacuum diode,establishes the mathematical model of the radiating microwave from the vacuum diode.Based on the analysis of the dispersion relation in the form of a refractive index,the electromagnetic waves generated in the vacuum diode will resonate.The included angle between the direction of the electromagnetic radiation and the initial motion direction of electron beam is 45 degrees.The paper isolates the electrostatic effect from the beam-plasma interaction when the electromagnetic radiation occurs.According to above analyses,the dispersion relations of radiation are obtained by solving the wave equation.The dispersion curves are also obtained based on the theoretical dispersion relations.The theoretical dispersion curves are consistent with the actual measurement time-frequency maps of the radiation.Theoretical deduction and experiments indicate that the reason for microwave radiating from the vacuum diode can be well explained by the interaction of the electron beam and magnetized plasma. 展开更多
关键词 beam-plasma interaction dispersion relation dispersion curve wide band microwave radiation
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Fabrication of narrow pulse passively Q-switched self-stimulated Raman laser with c-cut Nd:GdVO_4 认领 引用 被引量：1
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作者 SHEN Gao LI Zuo-han HAN Ming 《Optoelectronics Letters》 EI 2016年第6期430-432,共3页
Combining the self-stimulated Raman scattering technology and saturable absorber of Cr4+:YAG,a 1.17μm c-cut Nd:GdVO_4 picosecond Q-switched laser is demonstrated in this paper.With an incident pump power of 10 W,t... Combining the self-stimulated Raman scattering technology and saturable absorber of Cr4+:YAG,a 1.17μm c-cut Nd:GdVO_4 picosecond Q-switched laser is demonstrated in this paper.With an incident pump power of 10 W,the Q-switched laser with average power of 430 mW for 1.17μm,pulse width of 270 ps,repetition rate of 13 kHz and the first order Stokes conversion efficiency of 4.3%is obtained.The Q-switched pulse width can be the narrowest in our research.In addition,the yellow laser at 0.58μm is also achieved by using the LiB_3O_5 frequency doubling crystal. 展开更多
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Text Understanding with a Hybrid Neural Network Based Learning 认领 引用
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作者 Shen Gao Huaping Zhang Kai Gao 《国际计算机前沿大会会议论文集》 EI 2017年第2期26-28,共3页
Teaching machine to understand needs to design an algorithm for the machine to comprehend documents. As some traditional methods cannot learn the inherent characters effectively, this paper presents a new hybrid neura... Teaching machine to understand needs to design an algorithm for the machine to comprehend documents. As some traditional methods cannot learn the inherent characters effectively, this paper presents a new hybrid neural network model to extract sentence-level summarization from single document,and it allows us to develop an attention based deep neural network that can learn to understand documents with minimal prior knowledge. The proposed model composed of multiple processing layers can learn the representations of features.Word embedding is used to learn continuous word representations for constructing sentence as input to convolutional neural network. The recurrent neural network is also used to label the sentences from the original document, and the proposed BAM-GRU model is more efficient. Experimental results show the feasibility of the approach. Some problems and further works are also present in the end. 展开更多
关键词 Deep learning Convolutional neural network Recurrent neural network Word embedding Gated recurrent unit
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美容用低能量光学类医疗器械的注册监管要求探讨 认领 引用 被引量：2
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作者 申高 李敏 +1 位作者 王泽华 邱宏 《中国激光医学杂志》 CAS 2023年第6期345-348,共4页
激光、强脉冲光等光学类医疗器械自20世纪80年代应用于美容领域以来,产品的技术和应用发展迅速。其中低能量的光学设备由于监管属性尚存争议,其生产、经营和使用情况混乱,具有较大的安全隐患。本文通过分析国际国内发布的相关标准、美... 激光、强脉冲光等光学类医疗器械自20世纪80年代应用于美容领域以来,产品的技术和应用发展迅速。其中低能量的光学设备由于监管属性尚存争议,其生产、经营和使用情况混乱,具有较大的安全隐患。本文通过分析国际国内发布的相关标准、美国食品药品监督管理局(food and drug administration,FDA)出台的指南及我国已发布的相关指导原则,以期总结国内外相关经验,为此类产品在我国的注册监管提供思路和建议,确保上市产品的安全有效。 展开更多
关键词 低能量 激光 强脉冲光 医疗器械 注册监管
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能量治疗类设备量效关系和能量安全研究资料要求概况及探讨 认领 引用 被引量：1
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作者 申高 常凤翥 《应用激光》 CSCD 北大核心 2024年第10期221-226,共6页
量效关系和能量安全研究资料是能量治疗类产品注册申报资料中的非临床研究资料的组成部分,其对于评价产品的安全有效性起着重要的作用。本文通过对已发布指导原则中的相关内容进行梳理,从而明确光学、超声、射频、微波等各类能量治疗产... 量效关系和能量安全研究资料是能量治疗类产品注册申报资料中的非临床研究资料的组成部分,其对于评价产品的安全有效性起着重要的作用。本文通过对已发布指导原则中的相关内容进行梳理,从而明确光学、超声、射频、微波等各类能量治疗产品的特定要求,厘清量效关系和能量安全的概念,对能量治疗类产品的该部分注册申报研究资料提出细化的要求,以期为注册申请人及相关从业人员对相关内容资料的撰写提供帮助和指导。 展开更多
关键词 能量治疗设备 量效关系 能量安全 研究资料要求
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医用激光设备动物试验的决策与审评要求探讨 认领 引用 被引量：1
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作者 刘柏东 申高 +1 位作者 邱宏 陈民利 《中国比较医学杂志》 CAS 北大核心 2022年第6期148-154,共7页
医用激光设备是向人体靶组织输出能量的电气设备,动物试验是激光设备开展非临床/临床评价的重要手段之一,也可作为该类设备在临床试验前提供安全性和有效性的证据。本文通过参考现有医疗器械动物试验相关的法规、标准、指南,分析医用激... 医用激光设备是向人体靶组织输出能量的电气设备,动物试验是激光设备开展非临床/临床评价的重要手段之一,也可作为该类设备在临床试验前提供安全性和有效性的证据。本文通过参考现有医疗器械动物试验相关的法规、标准、指南,分析医用激光设备的作用机理;结合常见激光治疗设备的审评经验,概述了激光治疗设备决策开展动物试验研究的考量因素及规范要求;并举例分析了开展动物试验的目的、方案设计要求和评价指标;为医用激光治疗设备的动物试验研究提供参考,也可供该类医疗器械相关的技术审评人员及注册人员参考。 展开更多
关键词 医用激光设备 临床前动物试验 审评要求
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医疗美容类激光设备适用范围的审评要点 认领 引用 被引量：1
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作者 邱宏 申高 刘柏东 《医疗装备》 2023年第17期37-40,共4页
医疗美容类激光设备的适用范围与该类设备作用于人体的机制密切相关。该研究从医疗器械审评角度总结医疗美容类激光设备的适用范围,为注册人和技术审评部门科学、合理地评价该类设备的安全性和有效性提供参考。
关键词 医疗美容 激光设备 适用范围 技术审评
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一种面向SoC的能量迹预处理方法 认领 引用
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作者 蔡晓敏 李仁发 +2 位作者 李少青 沈高 邝世杰 《计算机工程与科学》 CSCD 北大核心 2020年第9期1538-1543,共6页
差分功耗攻击技术是恢复密码设备密钥最有效的攻击手段之一,但在攻击过程中,如果使用不合适的采样点,将引入额外噪声,会降低攻击成功率。为此,提出了一种基于能量模型的能量迹分类方法,旨在定位能量迹中与密钥具有较强相关性的特征点。... 差分功耗攻击技术是恢复密码设备密钥最有效的攻击手段之一,但在攻击过程中,如果使用不合适的采样点,将引入额外噪声,会降低攻击成功率。为此,提出了一种基于能量模型的能量迹分类方法,旨在定位能量迹中与密钥具有较强相关性的特征点。分别利用汉明距离和汉明重量2种能量模型定位特征点,截取特征点附近少量采样点构成特征区间。攻击不同密钥下载有128位AES算法的SoC芯片,实测结果表明:利用汉明距离能量模型得到的最佳特征区间的长度较短。最终,基于汉明距离能量模型得到的特征点定位方法具有较低的样本计算量,且缩减了大量的样本量。 展开更多
关键词 差分功耗攻击 片上系统SoC 能量模型 特征点 特征区间 能量迹
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医疗美容类激光产品技术审评的关注点 认领 引用
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作者 刘柏东 申高 邱宏 《医疗装备》 2021年第15期45-47,共3页
激光医学是生物医学与激光技术的交叉领域,激光产品作用于人体的作用机理与其预期用途息息相关。技术审评可从医疗器械安全有效基本要求出发,综合衡量激光产品的所有风险以及非预期影响,要求其均应最小化并可接受,在正常使用中受益大于... 激光医学是生物医学与激光技术的交叉领域,激光产品作用于人体的作用机理与其预期用途息息相关。技术审评可从医疗器械安全有效基本要求出发,综合衡量激光产品的所有风险以及非预期影响,要求其均应最小化并可接受,在正常使用中受益大于风险。该文从医疗器械注册技术审评的角度,分析医疗美容类激光产品在医疗器械技术审评过程中的主要关注点,为注册人/申请人和技术审评部门科学、合理地评价医疗美容类激光产品的安全性、有效性提供参考。 展开更多
关键词 医疗美容 激光 技术审评 关注点
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