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Antibody screening for tumor and immune hotspot targets:The frontier of new methods and technologies 认领 引用 被引量：1
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作者 Yaping Zhou Yitan Zou +6 位作者 Shaodong Lv Dan Tan Guangyao Li Wenyan Fu Changhai Lei Mingdong Lu Shi Hu 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2026年第2期393-412,共20页
Advancements in tumor immunotherapy highlight the significant potential of antibody drugs,a key category of biological agents,for treating cancer and autoimmune diseases.This paper begins by defining and classifying k... Advancements in tumor immunotherapy highlight the significant potential of antibody drugs,a key category of biological agents,for treating cancer and autoimmune diseases.This paper begins by defining and classifying key targets in tumor immunity,as well as discussing their structural and functional characteristics.Subsequently,it elaborates on innovative technologies for antibody drug screening,which,when integrated with contemporary molecular biology,biotechnology,and computational biology,have substantially enhanced the efficiency and accuracy of target identification and antibody drug screening processes.Despite the promising prospects of tumor immunotherapy,certain limitations persist in its practical implementation.In conclusion,this paper offers a comprehensive examination of the cutting-edge developments in tumor immunotherapy,focusing on the aspects of tumor immunotherapy itself,critical targets for immunotherapy,and novel technologies and methodologies for antibody screening.This analysis is crucial for advancing the field of tumor immunotherapy and for enhancing both therapeutic efficacy and safety.Furthermore,research and development(R&D)of antibody drugs in other domains,such as autoimmune and inflammatory diseases,can benefit from it. 展开更多
关键词 Tumor immunotherapy Hotspot targets Antibody drug screening Target discovery Innovative technologies and methods
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Real-Time 7-Core SDM Transmission System Using Commercial 400 Gbit/s OTN Transceivers and Network Management System 认领 引用
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作者 CUI Jian GU Ninglun +2 位作者 CHANG Cheng SHI Hu YAN Baoluo 《ZTE Communications》 2025年第3期81-88,共8页
Space-division multiplexing(SDM)utilizing uncoupled multi-core fibers(MCF)is considered a promising candidate for nextgeneration high-speed optical transmission systems due to its huge capacity and low inter-core cros... Space-division multiplexing(SDM)utilizing uncoupled multi-core fibers(MCF)is considered a promising candidate for nextgeneration high-speed optical transmission systems due to its huge capacity and low inter-core crosstalk.In this paper,we demonstrate a realtime high-speed SDM transmission system over a field-deployed 7-core MCF cable using commercial 400 Gbit/s backbone optical transport network(OTN)transceivers and a network management system.The transceivers employ a high noise-tolerant quadrature phase shift keying(QPSK)modulation format with a 130 Gbaud rate,enabled by optoelectronic multi-chip module(OE-MCM)packaging.The network management system can effectively manage and monitor the performance of the 7-core SDM OTN system and promptly report failure events through alarms.Our field trial demonstrates the compatibility of uncoupled MCF with high-speed OTN transmission equipment and network management systems,supporting its future deployment in next-generation high-speed terrestrial cable transmission networks. 展开更多
关键词 multi-core fiber real-time transmission optical transport network field trial network management system
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应用环境对硅基霍尔传感器芯片灵敏度影响 认领 引用
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作者 陈军 石虎 +3 位作者 刘佳 朱俊达 曾博 柴胤鑫 《传感器世界》 2026年第5期33-38,共6页
可靠性试验用于模拟霍尔芯片在应用环境下的表现,针对硅基霍尔芯片在可靠性预处理后灵敏度异常升高问题,系统研究了预处理过程高温烘烤、潮敏试验及热回流对硅基霍尔灵敏度的影响。结果表明,高温烘烤、潮敏试验对灵敏度影响较小,而热回... 可靠性试验用于模拟霍尔芯片在应用环境下的表现,针对硅基霍尔芯片在可靠性预处理后灵敏度异常升高问题,系统研究了预处理过程高温烘烤、潮敏试验及热回流对硅基霍尔灵敏度的影响。结果表明,高温烘烤、潮敏试验对灵敏度影响较小,而热回流前后,灵敏度变化率达0.85%,是导致霍尔芯片灵敏度稳定性变化的主要因素。热回流具有快速升降温特点,致使霍尔芯片的封装应力发生变化;而硅基霍尔具有压阻效应,封装应力会导致芯片电阻发生改变,影响静态电流及不同磁场强度下的输出电压。灵敏度与输出电压的变化率正相关,因此,封装应力通过影响芯片电阻间接导致芯片灵敏度稳定性变化。 展开更多
关键词 硅基霍尔 可靠性试验 封装应力 灵敏度
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极薄镀锌板冷连轧流程板形控制实践 认领 引用
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作者 李靖 齐海峰 +1 位作者 史虎 马进峰 《金属制品》 CAS 2025年第1期61-63,共3页
从生产实践角度分析了极薄镀锌板板形缺陷的产生原因,结果表明带钢边部覆盖函数直接影响板形。从冷硬带钢板形、光整机板形和拉矫机板形3个方面采取控制措施。对板形控制程序进行解析,将冷硬带钢边部覆盖率降至50.0%。根据经验设定光整... 从生产实践角度分析了极薄镀锌板板形缺陷的产生原因,结果表明带钢边部覆盖函数直接影响板形。从冷硬带钢板形、光整机板形和拉矫机板形3个方面采取控制措施。对板形控制程序进行解析,将冷硬带钢边部覆盖率降至50.0%。根据经验设定光整机前后带钢张力和轧制力等参数,镀锌生产线拉矫机延伸率设定为恒定值控制,适当增加拉矫机延伸率,将拉矫机延伸率增加0.1%,调整带钢边部覆盖函数可以对带钢板形控制起到积极作用,镀锌生产线光整机和拉矫机的协同作用也可有效改善带钢板形。 展开更多
关键词 镀锌板 冷连轧 板形仪 光整机 延伸率 覆盖函数
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Experiments and Simulation of Thermal Behaviors of the Dual-drive Servo Feed System 认领 引用 被引量：9
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作者 YANG Jun MEI Xuesong +3 位作者 FENG Bin ZHAO Liang MA Chi SHI Hu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2015年第1期76-87,共12页
The machine tool equipped with the dual-drive servo feed system could realize high feed speed as well as sharp precision. Currently, there is no report about the thermal behaviors of the dual-drive machine, and the cu... The machine tool equipped with the dual-drive servo feed system could realize high feed speed as well as sharp precision. Currently, there is no report about the thermal behaviors of the dual-drive machine, and the current research of the thermal characteristics of machines mainly focuses on steady simulation. To explore the influence of thermal characterizations on the precision of a jib boring machine assembled dual-drive feed system, the thermal equilibrium tests and the research on thermal-mechanical transient behaviors are carried out. A laser interferometer, infrared thermography and a temperature-displacement acquisition system are applied to measure the temperature distribution and thermal deformation at different feed speeds. Subsequently, the finite element method （FEM） is used to analyze the transient thermal behaviors of the boring machine. The complex boundary conditions, such as heat sources and convective heat transfer coefficient, are calculated. Finally, transient variances in temperatures and deformations are compared with the measured values, and the errors between the measurement and the simulation of the temperature and the thermal error are 2 ~C and 2.5 pm, respectively. The researching results demonstrate that the FEM model can predict the thermal error and temperature distribution very well under specified operating condition. Moreover, the uneven temperature gradient is due to the asynchronous dual-drive structure that results in thermal deformation. Additionally, the positioning accuracy decreases as the measured point became further away from the motor, and the thermal error and equilibrium period both increase with feed speeds. The research proposes a systematical method to measure and simulate the boring machine transient thermal behaviors. 展开更多
关键词 dual-drive feed system thermal deformation temperature distribution thermal characteristics measurement FEM
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Intermetallic CuAu nanoalloy for stable electrochemical CO2 reduction 认领 引用 被引量：1
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作者 Siyu Kuang Minglu Li +6 位作者 Xiaoyi Chen Haoyuan Chi Jianlong Lin Zheng Hu Shi Hu Sheng Zhang Xinbin Ma 《Chinese Chemical Letters》 SCIE CAS CSCD 2023年第7期226-229,共4页
Copper is one of the most efficient catalysts widely investigated in electrochemical CO2 reduction, however, the further development of copper-based catalysts is constrained by severe stability problems. In this wo... Copper is one of the most efficient catalysts widely investigated in electrochemical CO2 reduction, however, the further development of copper-based catalysts is constrained by severe stability problems. In this work, we developed a method for the synthesis of highly ordered Cu Au intermetallic nanoalloys(o-CuAu) under mild conditions(< 250℃), which can convert carbon dioxide to carbon monoxide with high selectivity and can operate stably for 160 h without current decay. The improved stability is believed to be due to the increased mixing enthalpy and stronger atomic interactions between Cu and Au atoms in the intermetallic nanoalloy. In addition, XPS results, Tafel slope and in situ IR spectroscopy demonstrate that high valence gold atoms on o-CuAu surface promote the reduction of CO2. In contrast, the disordered CuAu nanoalloy(d-CuAu) underwent atomic rearrangement to form a Cu-rich structure on the surface, leading to reduced stability. These findings may provide insight into the rational design of stable CO2 RR electrocatalysts through proper structural engineering. 展开更多
关键词 CO2reduction CuAu nanoalloy Intermetallic Stability Electrocatalysts
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Toward Low-Cost Flexible Intelligent OAM in Optical Fiber Communication Networks 认领 引用 被引量：1
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作者 YAN Baoluo WU Qiong +8 位作者 SHI Hu ZHAO Yan JIA Yinqiu FENG Zhenhua CHEN Weizhang ZHU Mo ZHAO Zhiyong FANG Yu CHEN Yong 《ZTE Communications》 2022年第3期54-60,共7页
Low-cost,flexible and intelligent optical performance monitoring and management is a key enabling technology for network quality guarantee,especially in the era of explosive growth of communication capacity and networ... Low-cost,flexible and intelligent optical performance monitoring and management is a key enabling technology for network quality guarantee,especially in the era of explosive growth of communication capacity and network scale.However,to the best of our knowledge,it is extremely challenging to implement real-time performance monitoring and operations,administration and maintenance(OAM) in a highly complex dynamic network.In this paper,we propose an innovative optical identification(OID) scheme that can realize both performance monitoring and some advanced OAM sub-functions.The basic concepts,applications,challenges and evolution directions of this OID tool are also discussed. 展开更多
关键词 fiber optics communication optical performance monitoring pilot tone wavelength-division multiplexing(WDM)
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Global sensitivity and uncertainty analysis of the VIP ecosystem model with an expanded soil nitrogen module for winter wheat-summer maize rotation system in the North China Plain 认领 引用
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作者 Lihong HE Xingguo MO +1 位作者 Shi HU Suxia LIU 《Pedosphere》 SCIE CAS CSCD 2021年第5期822-838,共17页
Accurately simulating the soil nitrogen(N)cycle is crucial for assessing food security and resource utilization efficiency.The accuracy of model predictions relies heavily on model parameterization.The sensitivity and... Accurately simulating the soil nitrogen(N)cycle is crucial for assessing food security and resource utilization efficiency.The accuracy of model predictions relies heavily on model parameterization.The sensitivity and uncertainty of the simulations of soil N cycle of winter wheat-summer maize rotation system in the North China Plain(NCP)to the parameters were analyzed.First,the N module in the Vegetation Interface Processes(VIP)model was expanded to capture the dynamics of soil N cycle calibrated with field measurements in three ecological stations from 2000 to 2015.Second,the Morris and Sobol algorithms were adopted to identify the sensitive parameters that impact soil nitrate stock,denitrification rate,and ammonia volatilization rate.Finally,the shuffled complex evolution developed at the University of Arizona(SCE-UA)algorithm was used to optimize the selected sensitive parameters to improve prediction accuracy.The results showed that the sensitive parameters related to soil nitrate stock included the potential nitrification rate,Michaelis constant,microbial C/N ratio,and slow humus C/N ratio,the sensitive parameters related to denitrification rate were the potential denitrification rate,Michaelis constant,and N2 O production rate,and the sensitive parameters related to ammonia volatilization rate included the coefficient of ammonia volatilization exchange and potential nitrification rate.Based on the optimized parameters,prediction efficiency was notably increased with the highest coefficient of determination being approximately 0.8.Moreover,the average relative interval length at the 95% confidence level for soil nitrate stock,denitrification rate,and ammonia volatilization rate were 11.92,0.008,and 4.26,respectively,and the percentages of coverage of the measured values in the 95% confidence interval were 68%,86%,and 92%,respectively.By identifying sensitive parameters related to soil N,the expanded VIP model optimized by the SCE-UA algorithm can effectively simulate the dynamics of soil nitrate stock,denitrification rate,and ammonia volatilization rate in the NCP. 展开更多
关键词 ammonia volatilization denitrification rate global sensitivity analyses shuffled complex evolution developed at the University of Arizona(SCE-UA)algorithm vegetation interface processes model
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多孔交联纳米纤维基超级电容器隔膜的设计 认领 引用
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作者 时虎 王赫 +1 位作者 王洪杰 潘显苗 《纺织学报》 EI CAS CSCD 北大核心 2025年第8期45-52,共8页
为制备高性能储能器件隔膜材料,采用聚丙烯腈(PAN)、淀粉、聚乙烯吡咯烷酮(PVP)为前驱体,先后通过静电纺丝法、水溶解和戊二醛交联改性,获得多孔交联的纳米纤维膜。分别测试了纳米纤维膜的表面形貌、接触角、孔隙率以及力学性能。结果表... 为制备高性能储能器件隔膜材料,采用聚丙烯腈(PAN)、淀粉、聚乙烯吡咯烷酮(PVP)为前驱体,先后通过静电纺丝法、水溶解和戊二醛交联改性,获得多孔交联的纳米纤维膜。分别测试了纳米纤维膜的表面形貌、接触角、孔隙率以及力学性能。结果表明:在交联处理后的纳米纤维膜中纤维之间出现黏结点,纤维直径为100~300 nm,改性后纤维膜的亲水性、力学强度和孔隙率均得到一定程度的提高;当三者的质量比为5∶4∶1时,纳米纤维膜的综合性能最佳,厚度为0.09 mm,拉伸断裂强度为11.44 MPa,接触角为36.46°,孔隙率高达88.02%;此外,当其作为隔膜应用于超级电容器中,所制备的器件表现出较好的电化学性能,经过5000次充放电循环后比电容保持率高达96.22%,显示出优异的循环稳定性。 展开更多
关键词 静电纺丝 纳米纤维 超级电容器 隔膜 戊二醛交联 聚丙烯腈 淀粉 聚乙烯吡咯烷酮
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弹簧式恒压蓄能器的设计与仿真研究 认领 引用 被引量：2
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作者 陈鑫叶 施虎 王海涛 《液压气动与密封》 2025年第1期1-6,共6页
针对传统蓄能器在蓄能和释能过程中压力变化大容易引起系统压力不稳定的问题,提出了一种基于弹簧储能的恒压蓄能器。首先分析装置的工作原理,然后推导并求解关键零件凸轮的轮廓曲线方程。对某液压系统蓄能器的关键参数进行设计,在ADAMS... 针对传统蓄能器在蓄能和释能过程中压力变化大容易引起系统压力不稳定的问题,提出了一种基于弹簧储能的恒压蓄能器。首先分析装置的工作原理,然后推导并求解关键零件凸轮的轮廓曲线方程。对某液压系统蓄能器的关键参数进行设计,在ADAMS软件中搭建其仿真模型,对流量变化时蓄能器的恒压效果进行了模拟验证,稳定工作时恒力偏差在1%以内。为液压式储能设计提供参考依据。 展开更多
关键词 恒压蓄能器 弹簧 凸轮设计 ADAMS仿真 力偏差
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数字孪生技术在危化品港口信息化建设中的应用研究 认领 引用 被引量：2
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作者 李腾飞 刘加强 +1 位作者 时虎 屈刚 《通信与信息技术》 2025年第4期32-35,共4页
近年来,危化品生产安全受到政府监管部门的高度重视,要求各相关单位充分利用信息化手段提升危化品生产安全管理水平。随着信息技术的飞速发展,数字孪生逐渐成为驱动各行各业信息化建设的重要手段之一。针对危化品港口危险系数高、管理... 近年来,危化品生产安全受到政府监管部门的高度重视,要求各相关单位充分利用信息化手段提升危化品生产安全管理水平。随着信息技术的飞速发展,数字孪生逐渐成为驱动各行各业信息化建设的重要手段之一。针对危化品港口危险系数高、管理难度大等问题,提出了基于数字孪生技术的危化品港口信息化建设方案,包括数字孪生危化品港口的建设框架、实施路径等,为危化品港口信息化建设提供理论支持和实践指导,提升危化品港口安全生产、管理水平。 展开更多
关键词 数字孪生 危化品港口 信息化 生产安全
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Au nanowires with high aspect ratio and atomic shell of Pt-Ru alloy for enhanced methanol oxidation reaction 认领 引用 被引量：5
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作者 Xiran Zhu Zheng Hu +3 位作者 Ming Huang Yuxin Zhao Jianqiang Qu Shi Hu 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第6期2033-2037,共5页
The methanol oxidation reaction(MOR)is the limiting half-reaction in direct methanol fuel cell(DMFC).Although Pt is the most active single-metal electrocatalyst for MOR,it is hampered by high cost and CO poisoning.Con... The methanol oxidation reaction(MOR)is the limiting half-reaction in direct methanol fuel cell(DMFC).Although Pt is the most active single-metal electrocatalyst for MOR,it is hampered by high cost and CO poisoning.Constructing a Pt or Ru monolayer on a second metal substrate by means of galvanic replacement of underpotentially deposited(UPD)Cu monolayer has been shown as an efficient catalyst design strategy for the electrocatalysis of MOR because of the presumed 100%utilization of atoms and resistance to CO poisoning.Herein,we prepared one-dimensional surface-alloyed electrocatalyst from predominantly(111)faceted Au nanowires with high aspect ratio as the substrate of under-potential deposition.The electrocatalyst comprises a core of the Au nanowire and a shell of catalytically active Pt coated by Ru.Coverage-dependent electro-catalytic activity and stability is demonstrated on the Pt/Ru submonolayers on Au wires for MOR.Among all these catalysts,Au@PtML@RuMLexhibits the best electrocatalytic activity and poisoning tolerance to CO.This presents a viable method for the rational catalyst design for achieving high noble-metal utilization efficiency and high catalytic performance. 展开更多
关键词 Au nanowires Pt/Ru submonolayers Underpotentially deposited Core-shell nanostructure Methanol oxidation reaction
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红色文化视域下高校“一站式”学生社区综合管理模式探究 认领 引用 被引量：2
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作者 石虎 张文丽 李浩杰 《黑龙江科学》 2025年第21期104-106,共3页
分析红色文化核心内容与高校“一站式”学生社区综合管理模式的结合效果,通过问卷调查和数据分析验证了红色文化认同度与学生社区参与度、满意度、行为规范和服务质量之间存在显著正相关关系,红色文化在优化学生社区管理模式、提升服务... 分析红色文化核心内容与高校“一站式”学生社区综合管理模式的结合效果,通过问卷调查和数据分析验证了红色文化认同度与学生社区参与度、满意度、行为规范和服务质量之间存在显著正相关关系,红色文化在优化学生社区管理模式、提升服务质量等方面具有积极作用,且红色文化能够有效提升学生的思想政治素质、集体意识和社会责任感,促进学生全面发展。研究还发现不同年级、性别、专业的学生在红色文化认同度和管理模式满意度方面存在一定差异。基于研究结果,提出优化服务流程、提升服务质量等优化“一站式”学生社区综合管理模式的建议,为高校管理者提供决策参考。 展开更多
关键词 红色文化 一站式 学生社区管理模式
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一站式学生社区建设影响因素与评价方法探析 认领 引用 被引量：1
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作者 石虎 庞晓东 +1 位作者 胡西塔尔江·吾拉木 周丹 《黑龙江科学》 2025年第1期142-144,共3页
为探讨一站式学生社区建设的影响因素与评价方法,通过文献分析与专家访谈法确定了制度设计、资源配置与环境建设、学生需求与文化氛围等主要影响因素。采用层次分析法(AHP)构建相关评价体系,基于受访者的反馈计算指标层与准则层的权重... 为探讨一站式学生社区建设的影响因素与评价方法,通过文献分析与专家访谈法确定了制度设计、资源配置与环境建设、学生需求与文化氛围等主要影响因素。采用层次分析法(AHP)构建相关评价体系,基于受访者的反馈计算指标层与准则层的权重。结果表明,该评价体系能够科学评估一站式学生社区建设的各关键要素,能为进一步优化学生社区建设提供理论支持。 展开更多
关键词 一站式学生社区 层次分析法 综合服务平台 智能化管理系统 心理健康支持 学生需求 文化氛围
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飞机进气道巡检机器人叶片拨动机构设计与动力学特性分析 认领 引用
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作者 梁智心 施虎 +1 位作者 张博阳 耿涛 《内蒙古工业大学学报（自然科学版）》 2025年第1期1-8,共8页
针对目前飞机进气道内的发动机吸气叶片人工检测存在的问题,提出了飞机进气道机器人巡检方案,基于动力学仿真软件对吸气叶片拨动机构进行了参数设计与性能分析。采用平面四连杆机构作为叶片拨动执行机构,建立了机构的数学模型,通过粒子... 针对目前飞机进气道内的发动机吸气叶片人工检测存在的问题,提出了飞机进气道机器人巡检方案,基于动力学仿真软件对吸气叶片拨动机构进行了参数设计与性能分析。采用平面四连杆机构作为叶片拨动执行机构,建立了机构的数学模型,通过粒子群优化算法对拨杆末端轨迹综合问题进行了优化设计,得到了拨杆机构的几何尺寸和安装偏角。分析了拨杆末端与叶片接触的力学特性,在Adams环境中开展了叶片拨动过程的动力学仿真,得到了拨动叶片关键接触力和机构驱动力矩,为飞机进气道巡检机器人整机行走及支撑单元驱动设计提供了依据。 展开更多
关键词 吸气叶片拨动机构 平面四杆机构 粒子群优化 轨迹综合 Adams仿真
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Highly efficient labelling of extracellular vesicles for enhanced detection on a microfluidic platform 认领 引用
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作者 Shi Hu Rui Hao +2 位作者 Zitong Yu Huitao Zhang Hui Yang 《Chinese Chemical Letters》 SCIE CAS CSCD 2024年第2期441-445,共5页
Developing precise extracellular vesicles(EVs)labelling techniques with minimal disturbance is of great importance to the follow-up EVs detection and analysis.However,currently available methods such as using probes t... Developing precise extracellular vesicles(EVs)labelling techniques with minimal disturbance is of great importance to the follow-up EVs detection and analysis.However,currently available methods such as using probes to conjugate phospholipids or membrane proteins have certain limitations due to EV steric hindrance,dye aggregation,etc.Here,we present a microfluidic platform to enhance EVs’labelling efficiency and improve their detection.This platform provides excellent sample throughput and high-efficiency EV labelling at lower label concentrations with an optimized flowing rate.Flow cytometry analysis(FCM)and cellular uptake results show that EV labelling by utilizing this platform possesses the merits of a higher labelling efficiency with 64.1%relative improvement than conventional co-incubation method and a lower background noise.Moreover,this technique maintains EVs’size,morphology and biological activities.After the recipient cells uptake the EVs treated by the microfluidic platform,the spatial and temporal distribution of EVs in the cells are clearly observed.These results demonstrate that our method holds great potential in efficient labelling of EVs,which is essential to subsequent EV quantification and analysis. 展开更多
关键词 Microfluidic platform Extracellular vesicles Labelling PKH dye Flow cytometry
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机器人专业新型人才培养模式的探索与实践 认领 引用 被引量：9
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作者 王海涛 杨军 +3 位作者 梅雪松 霍婧琦 施虎 孙孝飞 《实验室研究与探索》 CAS 北大核心 2024年第3期208-212,共5页
分析了当前机器人专业人才培养所面临的各类问题,提出了一种“多维协同、层次递进”人才培养模式,并围绕建立“四维度、三层次”贯通式培养体系,突出需求导向、强化学科交叉、搭建创新实践平台设计了与其相适应的支撑体系,分析了该培养... 分析了当前机器人专业人才培养所面临的各类问题,提出了一种“多维协同、层次递进”人才培养模式,并围绕建立“四维度、三层次”贯通式培养体系,突出需求导向、强化学科交叉、搭建创新实践平台设计了与其相适应的支撑体系,分析了该培养模式的实施成效。实践表明:机器人专业新型人才培养模式的实施成效显著,可为其他学科专业人才培养提供借鉴和参考。 展开更多
关键词 智能制造 机器人 人才培养模式 产学研
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实验室压力容器管理方法的探索与研究 认领 引用 被引量：12
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作者 王海涛 梅雪松 +1 位作者 施虎 徐学武 《实验技术与管理》 CAS 北大核心 2020年第12期285-287,共3页
压力容器作为高校实验室的一类关键设备,其管理应贯穿高校实验室建设和管理全过程。该文采用调查、文献资料查阅等研究方法,分析了实验室压力容器安全管理的现状以及存在的主要问题,总结了压力容器常见故障及处理方法,并对压力容器安全... 压力容器作为高校实验室的一类关键设备,其管理应贯穿高校实验室建设和管理全过程。该文采用调查、文献资料查阅等研究方法,分析了实验室压力容器安全管理的现状以及存在的主要问题,总结了压力容器常见故障及处理方法,并对压力容器安全管理方法进行了探讨,以期为高校实验室压力容器管理提供思路与方法。 展开更多
关键词 实验室管理 压力容器 安全管理
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一种新型的气动爬杆机器人 认领 引用 被引量：16
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作者 李晨景 施虎 +2 位作者 何彬 陶劲羽 汪已森 《液压与气动》 北大核心 2019年第3期38-42,共5页
随着人工智能技术的迅速发展,各类智能机器人的研究也越来越受到人们关注。面向实际生活和工业应用中存在大量爬杆作业的需求,在分析现有爬杆机器人在实际应用中所存在问题的基础上,设计了一款能够快速攀上固定高台的新型气动驱动机器... 随着人工智能技术的迅速发展,各类智能机器人的研究也越来越受到人们关注。面向实际生活和工业应用中存在大量爬杆作业的需求,在分析现有爬杆机器人在实际应用中所存在问题的基础上,设计了一款能够快速攀上固定高台的新型气动驱动机器人。该机器人利用双作用气缸为主要执行元件,通过设计六连杆机构对圆柱杆进行夹紧,通过气缸提升实现机器人的爬杆动作,然后通过摩擦轮带动机器人旋转上台进行工作。首先对机器人进行了结构设计和建模,再通过COMSOL软件分析主要零件的力学性能,并在AMESim软件中完成提升和夹紧机构的运动仿真。分析结果表明,该气动爬杆机器人能够满足快速爬杆的要求。 展开更多
关键词 爬杆机器人 结构设计 连杆机构 气动系统
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室外通信机柜通风冷却节能性能研究 认领 引用 被引量：2
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作者 何伟 李静远 +3 位作者 石虎 邾茂盛 贾臻 徐昭 《暖通空调》 2024年第7期182-188,共7页
合肥地区室外空气温度全年约有77.5%的时间在25℃以下,利用CFD数值模拟对机柜进行气流组织优化,结果表明,在合肥地区可采用新风设备给室外通信机柜降温。为了充分利用室外自然冷却资源,在对合肥地区典型室外通信机柜进行现场测量和数值... 合肥地区室外空气温度全年约有77.5%的时间在25℃以下,利用CFD数值模拟对机柜进行气流组织优化,结果表明,在合肥地区可采用新风设备给室外通信机柜降温。为了充分利用室外自然冷却资源,在对合肥地区典型室外通信机柜进行现场测量和数值模拟的基础上,提出了空调与新风设备联动策略。该策略缩短了空调的运行时间,从而节约能源,结果表明,空调与新风设备联合运行时的能耗为空调单独运行时的46.8%。 展开更多
关键词 室外通信机柜 空调 新风设备 气流组织 自然冷却 数值模拟
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