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A case report of brain abscess caused by Nocardia cyriacigeorgica identified by metagenomic next-generation sequencing 认领 引用
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作者 Wenqing Tu Peiting Zeng +5 位作者 Zhuangtian Wu Zuyong Li Tao Yu Wenxian Zhang Ran Chen Lian Liang 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2026年第2期199-201,共3页
Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment.Nocardia cyriacigeorgica(N.cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,[1] and... Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment.Nocardia cyriacigeorgica(N.cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,[1] and has since been reported as an emerging clinically relevant pathogen worldwide.The diagnosis of nocardial infections remains challenging due to nonspecific symptoms and low culture sensitivity,resulting in high mortality.[2] Herein,we report a case of N.cyriacigeorgica brain abscess in an immunosuppressed patient who was successfully treated with antibiotics and surgery. 展开更多
关键词 immunosuppressed patient antibiotics nocardial infections Nocardia cyriacigeorgica clinically relevant pathogen brain abscess chronic bronchitis metagenomic next generation sequencing
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ZmCals12 impacts maize growth and development by regulating symplastic transport 认领 引用
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作者 Ziwen Shi Sheng Zhang +6 位作者 Qing He Xiaoyuan Wang Bo Yang Tao Yu Hongyang Yi Tingzhao Rong Moju Cao 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2026年第1期42-55,共14页
Carbohydrate partitioning from source to sink tissues is essential for plant growth and development.However,in maize(Zea mays L.),the molecular mechanisms by which callose synthase genes regulate this process remain l... Carbohydrate partitioning from source to sink tissues is essential for plant growth and development.However,in maize(Zea mays L.),the molecular mechanisms by which callose synthase genes regulate this process remain largely unexplored.This study demonstrates that mutation of maize callose synthase12(Zm Cals12)results in increased carbohydrate accumulation in photosynthetic leaves but decreased carbohydrate content in sink tissues,leading to plant dwarfing and male sterility.Histochemical β-glucuronidase(GUS)activity assay and m RNA in situ hybridization(ISH)revealed that Zm Cals12 expression mainly occurs in the vascular transport system.Zm Cals12 loss-of-function decreased callose synthase activity and callose deposition in plasmodesmatas(PDs)and surrounding phloem cells(PCs)of the vascular bundle.The drop-and-see(DANS)assay indicated reduced PD permeability in photosynthetic cells and diminished transport competence of leaf veins in Zmcals12 mutants,resulting in decreased symplastic transport.Paraffin section analysis revealed that less-developed vascular cells(VCs)in Zmcals12 mutants likely disrupted sugar transport,contributing to the pleiotropic phenotype.Furthermore,impaired sugar transport inhibited internode development by suppressing auxin(IAA)biosynthesis and signaling in Zmcals12 mutant.These findings elucidate the mechanism by which Zm Cals12-mediated callose deposition and symplastic transport regulate maize growth and development. 展开更多
关键词 maize ZmCals12 plasmodesmata(PD)permeability symplastic transport less-developed vascular cells(VCs) auxin(IAA)biosynthesis and signaling
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Boosted organic carbon accumulation in the Late Cretaceous Songliao Basin during marine incursion events 认领 引用
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作者 Ke-Rui Wu Yu Sun +4 位作者 Da-Ming Yang Fu-Li Fang Bai-Quan Yan Jie Zhou Tao Yu 《Petroleum Science》 SCIE EI CAS CSCD 2026年第4期1804-1816,共13页
Although the Late Cretaceous marine incursion events(MI)significantly boosted organic carbon(OC)accumulation in the Songliao Basin,their net effects and accumulation mechanisms have long been debated.By integrating hi... Although the Late Cretaceous marine incursion events(MI)significantly boosted organic carbon(OC)accumulation in the Songliao Basin,their net effects and accumulation mechanisms have long been debated.By integrating high-resolution geological data,multi-proxy paleoenvironmental analysis,and a machine learning-based approach for TOC prediction in Member 1 of the Qingshankou Formation,we reveal that total OC sediment accumulation rates(OCSAR)during high-intensity MI(HMI)increased by 28.8%compared to low-intensity MI(LMI)intervals,with the areal OCSAR of the study area rising from 0.43×10-2 to 0.55×10-2 GtC/(Myr·km2).The OC accumulation models during HMI and LMI are established:driven by the interplay of seawater influxes,basin morphology,and terrigenous inputs,which collectively modulated the bacterial sulfate reduction,redox conditions,and nutrient availability in the water column,the growth rate of areal OCSAR exhibited pronounced spatial heterogeneity,defining four distinct zones(Ⅰ–Ⅳ).The validation case from the Nenjiang Formation demonstrates the robustness of the models.These findings establish MI as a global amplifier of OC burial in megapaleolake systems and redefine resource development frameworks for lacustrine shales within MI sequences. 展开更多
关键词 Organic carbon accumulation Marine incursion events Qingshankou Formation Songliao Basin Lacustrine shale oil and gas Paleolake
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Modulating coordination environment of Bi active center atom for efficient photocatalytic water oxidation 认领 引用
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作者 Yuan Tang Chunyang Wang +7 位作者 Yuchen Guo Liang Mao Xiaoyan Cai Yanfang Li Boxin Liu Xin Tan Jinhua Ye Tao Yu 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第7期277-284,共8页
Photocatalytic water oxidation is considered as the bottleneck step for overall artificial photosynthesis,due to the slow photocarrier transfer kinetics and climbing thermodynamics.Developing the electronic structure ... Photocatalytic water oxidation is considered as the bottleneck step for overall artificial photosynthesis,due to the slow photocarrier transfer kinetics and climbing thermodynamics.Developing the electronic structure of catalytic with more dynamic-thermodynamic advantages is crucial to deal with the above dilemma and realize the photocatalytic water oxidation.This work successfully explores an S-induced modification strategy to induce electronic delocalization and non-equilibrium states for unique Bi active sites.The introduction of V4+species leads to asymmetric coordination of Bi atoms in the S-Bi-V4+structure to provide more nonlocalized electrons,which initiates a concerted electron transfer in the system.The fine regulation on the local electron density and energy level structure of the Bi active site optimizes the reaction energy barriers to construct thermodynamically more favourable active centers for water oxidation.The optimized 2% S-BVO catalyst achieves outstanding water oxidation rate of 70.25μmol/h(40 mg catalyst)triggering up to 11.06% apparent quantum efficiency at 420 nm.This work elucidates the influence of synergistic electron interaction of asymmetric coordination structure on both photocarrier transfer kinetics and reaction thermodynamic. 展开更多
关键词 S-induced modification strategy BiVO4 Water oxidation Synergistic electron interaction Photocatalysis
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Development and verification of a Monte Carlo dose calculation program“MagicDose”for boron neutron capture therapy 认领 引用
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作者 Ai‑Kou Sun Zhen‑Ping Chen +9 位作者 Ke‑Kun Gao Lin Zhu Cheng‑Wei Liu Zhi‑Qiang Wu Chao Yang Tong Liu Song Wang Zi‑Zhu Zhang Yi‑Zheng Chong Tao Yu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2026年第8期16-37,共22页
Dose calculation is the foundation of boron neutron capture therapy(BNCT).MagicDose,a dose calculation program for the BNCT treatment planning system,is developed based on the Monte Carlo method.First,the voxel phanto... Dose calculation is the foundation of boron neutron capture therapy(BNCT).MagicDose,a dose calculation program for the BNCT treatment planning system,is developed based on the Monte Carlo method.First,the voxel phantom of the modified Snyder head with 16 and 8 mm is constructed,and the results from MagicDose and MCNP are presented as two-dimensional coordinate points(Xn,Yn),comparing their relationship relative to the y=x linear function,while analyzing their respective calculation time.A modified Snyder head phantom with a tumor at three different spatial resolutions of 16,8,and 1 mm was constructed,and the depth-dose rate curves and spatial distribution maps are analyzed.Finally,the patients’head CT data were used for the application.The results indicate that the calculations from MagicDose and MCNP exhibit high consistency and demonstrate that MagicDose offers superior computational efficiency compared to MCNP,with improvements of approximately 31.24%and 28.65%at spatial resolutions of 16 and 8 mm,respectively.As the spatial resolution increased,the variability in the dose rate results decreased.The voxel size and number of threads are both inversely proportional to the calculation time.For the CT model,a voxel phantom with a spatial resolution of 1 mm×1 mm×1 mm is successfully constructed.The calculation results showed that the boron dose rate contribution significantly exceeds that of the other dose components,with the spatial distribution of the total relative biological effect dose rate clearly delineating the boundaries between the high-and low-dose rate regions.The above results verify the correctness of MagicDose,which also provides a reference for optimizing the design of voxel phantoms for clinical treatment. 展开更多
关键词 Boron neutron capture therapy(BNCT) Monte Carlo Dose calculation MCNP Voxel phantom Spatial resolution
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Multi-order evolution of lacustrine shale sedimentary structures in Qingshankou Formation of Songliao Basin,NE China,and its implications 认领 引用
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作者 Ke-Rui Wu Yu Sun +4 位作者 Jie Zhou Da-Ming Yang Bai-Quan Yan Li-Min Yu Tao Yu 《Petroleum Science》 SCIE EI CAS CSCD 2026年第5期2467-2484,共18页
Fine-grained sedimentology is crucial to understanding paleoclimatology and unconventional oil and gassedimentology.However,the controllingfactors andevolutionary patterns ofsedimentarystructuresin shale-the most fund... Fine-grained sedimentology is crucial to understanding paleoclimatology and unconventional oil and gassedimentology.However,the controllingfactors andevolutionary patterns ofsedimentarystructuresin shale-the most fundamental andwidespread featuresof fine-grained sediments-remain enigmatic.In this study,five types of organic-rich lacustrine shale sedimentary structures were identified in the lower Qingshankou Formation in Well C41-70 in the Songliao Basin:massive structures,layered structures,weakly laminated structures,laminated structures,and event sediment structures.Furthermore,Milankovitch cycles were identified using the gamma-ray logging curve of Well C41-70,and an astronomical time scale(ATs)was established.The frequencyand combinationpatterns of different types of sedimentary structures,referred to as"sedimentary structure evolution sets(SSESs)",exhibit covariations at multiple scales with changes in lake levels,short eccentricity,and precession.This suggests that lake levels and orbital cycles are the multi-order controls on SSESs variations.Crosswell correlations of geochemical proxies based on the ATSs further indicate that shifts in SSESs coincide with changes in the lacustrine sedimentary environment.Notably,marine incursion events appear to have induced significant variations in both the sedimentary environment and the SSESs.These findings implythat SSESs may preserve more information on paleoclimatic-paleoenvironmental changes and geological events,which challenges the conventional wisdom of strong heterogeneity and weak distribution patterns in sedimentary structures withinshale reservoirs.Furthermore,SSESs not only provide critical references for optimizing fracturing process parameters in lacustrine shale development,but also help reveal the dilution of organic matter during deposition and elucidate the genesis of TOC heterogeneity.This demonstrates the significant value of depiction and analysis of sedimentary structures for shale oil and gas exploration and development. 展开更多
关键词 Lacustrine shale Sedimentary structures Orbital cycle Lake levels Qingshankou Formation
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Fibroblast-directed melanocyte recruitment via Cxcl12–Cxcr4 axis promotes post-inflammatory hyperpigmentation and skin barrier protection in zebrafish 认领 引用
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作者 Shizheng Zhao Si Li +7 位作者 Chenyuliang Zhang Zheng Tang Ao Zhang Cong Huang Kefan Cheng Tao Yu Yan Yan Zilong Wen 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2026年第7期1305-1318,共14页
Post-inflammatory hyperpigmentation(PIH)is a common skin disorder characterized by brown or black macules.It can be categorized as transient,typically resolving within 6–12 months,or permanent,persisting for years.Wh... Post-inflammatory hyperpigmentation(PIH)is a common skin disorder characterized by brown or black macules.It can be categorized as transient,typically resolving within 6–12 months,or permanent,persisting for years.While the pathogenesis of PIH is commonly linked to localized melanocyte overactivation,the precise cellular and molecular basis for this dysregulation,as well as its physiological significance,remains poorly defined.Using an acetic acid-induced zebrafish model,we identify melanocyte migration as a critical driver of hyperpigmentation.This process is independent of immune cells but driven by fibroblasts,which secrete Cxcl12a to recruit melanocytes via the Cxcl12a–Cxcr4a axis.Fibroblast ablation irreversibly disrupts melanocyte patterning,indicating that aberrant fibroblast activity dictates the permanence of PIH.The recruited melanocytes form a dual protective barrier against both UV-induced DNA damage and microbial intrusion.The translational relevance of this mechanism is underscored by upregulated CXCL12 expression in fibroblasts from human PIH-related conditions such as keloids,acne,and atopic dermatitis.Therapeutically,the FDA-approved CXCR4 antagonist AMD3100(Plerixafor)effectively prevents and attenuates PIH in our model.Our findings elucidate a fibroblast-mediated mechanism of melanocyte recruitment in PIH,uncover previously unappreciated barrier functions of melanocytes in skin repair,and propose a promising repurposed treatment strategy. 展开更多
关键词 Zebrafish Post-inflammatory hyperpigmentation Fibroblast Melanocyte Migration
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A DEM–FEM coupling framework for particle–membrane interaction 认领 引用
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作者 Ning Guo Zhangbin Xu Tao Yu 《Particuology》 SCIE EI CAS CSCD 2026年第7期307-319,共13页
The interaction between granular materials and highly flexible membranes involves complex micromechanical contact and severe localized deformations,posing significant challenges for numerical modeling.Traditional pure... The interaction between granular materials and highly flexible membranes involves complex micromechanical contact and severe localized deformations,posing significant challenges for numerical modeling.Traditional pure discrete element method(DEM)approaches that employ bonded particle model(BPM)fail to capture the dynamic changes in surface roughness arising from membrane penetration into granular voids.This paper presents a GPU-parallelized explicit dynamic framework that couples DEM and the finite element method(FEM)to address this limitation.A total Lagrangian membrane element is implemented to capture geometric nonlinearity and follower loads,and is coupled with DEM through a penalty-based contact algorithm.The accuracy and robustness of the DEM–FEM coupling framework are validated against classical benchmarks for membrane inflation,penetration,and particle–membrane interaction.Finally,a 3D soil–geomembrane interface direct shear test,comprising over 170,000 particles at true physical scale,is simulated without artificial upscaling.The results successfully reproduce macroscopic strain-softening behavior and capture the underlying micromechanical interface mechanisms.By enabling the membrane topography to dynamically adapt to varying normal stresses,the proposed framework overcomes the static roughness limitations of BPM,providing a highly efficient computational tool for large-scale particle–membrane interaction problems. 展开更多
关键词 DEM–FEM Membrane element GPU parallelization Particle–membrane interaction
Hexagonal diamond formation mechanism:A review 认领 引用
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作者 Tao Yu Shengcai Zhu 《Matter and Radiation at Extremes》 SCIE EI CAS CSCD 2026年第3期1-12,共12页
As a metastable carbon allotrope,hexagonal diamond(HD)exhibits potentially superior mechanical properties to cubic diamond(CD).However,its synthesis faces significant thermodynamic and kinetic challenges.This review s... As a metastable carbon allotrope,hexagonal diamond(HD)exhibits potentially superior mechanical properties to cubic diamond(CD).However,its synthesis faces significant thermodynamic and kinetic challenges.This review summarizes the critical role of computational simulations in the synthesis of HD,covering both static calculations and molecular dynamics(MD)simulations.Static calculations reveal that graphite tends to transform into CD under interface-free conditions,whereas the presence of an interface results in a lower energy barrier for the HD phase transition.With regard to MD simulations,while early shock compression simulations failed to observe HD formation,recent studies based on neural network potentials have confirmed a shock-velocity-dependent transformation pathway and have successfully obtained HD,consistent with in situ experimental results.Hydrostatic pressure simulations emphasize the importance of controlling interlayer sliding,demonstrating that strategies such as quasi-uniaxial compression can promote the preferential formation of HD.In the future,the integration of high-precision simulations with experimental approaches is expected to enable the controllable synthesis of HD,thereby advancing its applications in ultrahard materials,power electronics,aerospace,and other fields. 展开更多
关键词 metastable carbon allotropehexagonal diamond hd exhibits molecular dynamics computational simulations static calculations hexagonal diamond cubic diamond cd howeverits shock compression
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X-Type Antiferromagnetic Stacking:Defying Magnonic Arithmetic 认领 引用
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作者 Tao Yu 《Chinese Physics Letters》 SCIE EI CAS CSCD 2026年第1期211-212,共2页
In physics,our expectations for system behavior are often guided by intuitive arithmetic.For systems composed of identical units,we anticipate synergy of the contributions from these units,where 1+1=2.Conversely,for s... In physics,our expectations for system behavior are often guided by intuitive arithmetic.For systems composed of identical units,we anticipate synergy of the contributions from these units,where 1+1=2.Conversely,for systems built from opposing units,we expect cancellation of their contributions,where 1-1=0.This intuitive arithmetic has long underpinned our understanding of physical properties of materials,from electronic transport to optical responses.However,scientific breakthroughs often occur when nature reveals ways to circumvent these seemingly fundamental rules,opening new possibilities that challenge our deepest assumptions about material behavior. 展开更多
关键词 intuitive arithmetic cancellation their contributionswhere understanding physical properties materialsfrom antiferromagnetic stacking synergy contributions unitswhere electronic transport magnons material behavior
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Odontogenic liver abscess in one patient 认领 引用
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作者 Huiling Lan Pengfei Wang +5 位作者 Shunhua Ye Meng Hu Junpeng Tang Li Li Tao Yu Fengqing Song 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2026年第3期288-290,共3页
Pyogenic liver abscess(PLA)is a life-threatening infection characterized by hepatic parenchymal suppurative necrosis,with biliary diseases(55%),hematogenous spread(12%),and cryptogenic origins(25.7%)as the main etiolo... Pyogenic liver abscess(PLA)is a life-threatening infection characterized by hepatic parenchymal suppurative necrosis,with biliary diseases(55%),hematogenous spread(12%),and cryptogenic origins(25.7%)as the main etiologies.[1,2]Odontogenic liver abscess(OLA)is an extremely rare subtype of PLA.We present a case of OLA diagnosed by metagenomic nextgeneration sequencing(mNGS)and successfully treated with percutaneous drainage and targeted antibiotics. 展开更多
关键词 liver abscess ola odontogenic liver abscess pyogenic liver abscess metagenomic nextgeneration sequencing mngs pyogenic liver abscess pla metagenomic next generation sequencing hepatic parenchymal suppurative necrosiswith percutaneous drainage
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Closed-loop dynamics and disturbance propagation mechanisms of a drag-free control ground-based validation system 认领 引用
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作者 Qixian Zhou Ke An +4 位作者 Pengcheng Wang Wei Lu Yonghe Zhang Huawang Li Tao Yu 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第5期488-503,共16页
In space-based gravitational wave detection missions and other space experiments utilizing the ultra-static and ultra-stable space-craft,the drag-free control system(DFCS)plays a key role in maintaining the free-falli... In space-based gravitational wave detection missions and other space experiments utilizing the ultra-static and ultra-stable space-craft,the drag-free control system(DFCS)plays a key role in maintaining the free-falling motion of the test masses(TMs).However,high-precision ground-based verification of DFCS faces a great challenge in suppressing and evaluating multiple dis-turbances and noises accurately.To this end,this article first proposes an active disturbance rejection controller for TM with a two-stage torsion pendulum.The dual-loop scheme with robust control approach is introduced for this underactuated pendulum system,which significantly reduces the impact of seismic noise on TM.Subsequently,on the basis of suspended TM and the controlled Stewart platform,the closed-loop dynamics of a ground-based DFCS validation system is conducted.The emulat-ing capability of this system for in-orbit flight dynamics is analyzed.Furthermore,complex propagation mechanism models of multiple disturbances and noises are built,and residual acceleration and tracking performance are precisely evaluated.?Finally,numerical simulations are performed to validate the theoretical work.The presented work provides a design and analysis method-ology for ground-based verification of DFCS. 展开更多
关键词 Drag-free control system Ultra-static and ultra-stable spacecraft Ground-based validation Active disturbance rejection control Dynamic similarity
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Conceptual design of the muonium-to-antimuonium conversion experiment(MACE) 认领 引用
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作者 Ai-Yu Bai Han-Jie Cai +49 位作者 Chang-Lin Chen Si-Yuan Chen Xu-Rong Chen Yu Chen Wei-Bin Cheng Ling-Yun Dai Rui-Rui Fan Li Gong Zi-Hao Guo Yuan He Zhi-Long Hou Yin-Yuan Huang Huan Jia Hao Jiang Han-Tao Jing Xiao-Shen Kang Hai-Bo Li Jin-Cheng Li Yang Li Da-Ming Liu Shu-Lin Liu Gui-Hao Lu Han Miao Yun-Song Ning Jian-Wei Niu Hua-Xing Peng Alexey APetrov Yuan-Shuai Qin Ming-Chen Sun Jian Tang Jing-Yu Tang Ye Tian Rong Wang Xiao-Dong Wang Yi Wang Zhi-Chao Wang Chen Wu Tian-Yu Xing Wei-Zhi Xiong Yu Xu Bao-Jun Yan De-Liang Yao Tao Yu Ye Yuan Yi Yuan Yao Zhang Yongchao Zhang Zhi-Lv Zhang Guang Zhao Shi-Han Zhao 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2026年第4期139-187,共49页
The spontaneous conversion of muonium to antimuonium is an interesting charged lepton flavor violation phenomenon that offers a sensitive probe for potential new physics and serves as a tool to constrain the parameter... The spontaneous conversion of muonium to antimuonium is an interesting charged lepton flavor violation phenomenon that offers a sensitive probe for potential new physics and serves as a tool to constrain the parameter space beyond the Standard Model.The Muonium-to-Antimuonium Conversion Experiment(MACE)was designed to utilize a high-intensity muon beam,a Michel electron magnetic spectrometer,a positron transport system,and a positron detection system to either discover or constrain this rare process with a conversion probability of O(10-13).This article presents an overview of the theoretical framework and a detailed description of the experimental design for muonium-to-antimuonium conversion. 展开更多
关键词 Muonium Lepton flavor violation Muon beam Drift chamber Microchannel plate Electromagnetic calorimeter
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Development of a transient neutronics and thermal‑hydraulics coupling method for TRIGA reactor 认领 引用
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作者 Yi‑Qing Zhang Ai‑Kou Sun +4 位作者 Cheng‑Wei Liu Ya‑Nan Zhao Tao Yu Qian Guo Zhen‑Ping Chen 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2026年第7期248-263,共16页
The interaction and feedback between 3D neutronics and thermal hydraulics are of great significance in reactor safety analyses,particularly for the TRIGA reactor.Owing to the TRIGA reactor’s pulse-transient operation... The interaction and feedback between 3D neutronics and thermal hydraulics are of great significance in reactor safety analyses,particularly for the TRIGA reactor.Owing to the TRIGA reactor’s pulse-transient operation status,the power changes by six to eight orders of magnitude within an extremely short duration;this operation is significantly different from PWRs and imposes some challenges for conventional neutronics methods.To describe the transient status of rod insertion or withdrawal,a novel time-dependent particle transport algorithm based on the combined and moving geometry methods is developed and integrated into the neutronics code MagicMC,which is a Monte Carlo particle transport code developed by the Nuclear Energy and Application Laboratory.Combined with the subchannel model,this work presents neutronics and thermal-hydraulics coupling methods for high-fidelity simulation of the TRIGA reactor.First,a steady-state coupling method is established based on over-relaxation iteration,and the number of neutrons in the Monte Carlo simulation is adaptively controlled according to convergence.Subsequently,a transient coupling method is proposed based on the semi-implicit coupling strategy,and a dynamically changing time-step strategy is designed for the coupling iterative process to achieve reasonable convergence.The parameter mapping strategy between neutronics and thermal hydraulics was constructed using one-to-one mapping and volume weight methods.To verify the reliability of the methods,a JSI TRIGA Mark Ⅱ reactor was selected as the validation benchmark.The coupling results were in good agreement with the experimental data of the JSI TRIGA Mark Ⅱ reactor,and the coupling methods achieved a high-fidelity numerical simulation of TRIGA reactor.Therefore,the coupling methods proposed in this paper can provide technical support for reactor experiments and the safe operation of the TRIGA reactor. 展开更多
关键词 Neutronics Thermal-hydraulics Time-dependent Monte Carlo Transient coupling TRIGA reactor
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TRUNCATED TOEPLITZ OPERATORS ON A CLASS OF QUOTIENT MODULES OVER THE BIDISK 认领 引用
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作者 Hong ZOU Tao YU 《Acta Mathematica Scientia》 SCIE CSCD 2026年第4期1581-1602,共22页
In this paper,we study truncated Toeplitz operators and little truncated Hankel operators on Np,q-type quotient modules over the bidisk.We find a necessary and sufficient condition for a truncated Toeplitz operator to... In this paper,we study truncated Toeplitz operators and little truncated Hankel operators on Np,q-type quotient modules over the bidisk.We find a necessary and sufficient condition for a truncated Toeplitz operator to be zero,as a result,we find a characterization equation for bounded truncated Toeplitz operators.We also find a necessary and sufficient condition for a little truncated Hankel operator to be zero operator.This paper also studies the spectra,joint spectra and the essential spectra of truncated Toeplitz operators with some special symbols. 展开更多
关键词 truncated Toeplitz operator little truncated Hankel operator Hardy space bidisk spectrum
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梭梭根际、内生细菌的促生作用及其复合菌群的构建 认领 引用 被引量：3
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作者 高艳东 候可心 +4 位作者 李俊达 刘扬 陶羽 王志林 刘惠荣 《微生物学通报》 CAS CSCD 北大核心 2026年第3期1468-1487,共20页
【背景】植物根际和内生菌凭借其促生、抗逆及定殖能力成为微生物肥料的主要菌种来源。梭梭作为荒漠抗逆先锋树种及肉苁蓉主要寄主,其根际与内生微生物的促生功能研究尚比较匮乏。【目的】筛选梭梭根际及内生细菌中的促生菌株,为梭梭的... 【背景】植物根际和内生菌凭借其促生、抗逆及定殖能力成为微生物肥料的主要菌种来源。梭梭作为荒漠抗逆先锋树种及肉苁蓉主要寄主,其根际与内生微生物的促生功能研究尚比较匮乏。【目的】筛选梭梭根际及内生细菌中的促生菌株,为梭梭的可持续繁育提供微生物菌种资源。【方法】从内蒙古磴口县乌兰布和沙漠采集梭梭根际土和植株样品,分离纯化梭梭根际和内生细菌,并探究其对梭梭幼苗的促生效果,对具有显著促生效果的菌株进行分子生物学鉴定和促生功能分析,选择不同种属间能力最强的菌株构建人工复合菌群,并检测复合菌群对梭梭的促生效果。【结果】共分离得到97株梭梭根际细菌和68株内生细菌,5株根际细菌具有显著促生作用,其分属于4个属和4个种,假单胞菌属(Pseudomonas)为优势菌属,占比为40%;12株内生细菌具有显著促生作用,其分属于7个属和12个种,芽孢杆菌属(Bacillus)为优势菌属,占比为25%。这些促生菌株均有较高水平的固氮、解无机磷、解钾长石和产生物膜的能力;大多数菌株都具有解有机磷、解硅酸铝钾、产铁载体和产IAA的能力。人工复合菌群中,其中4个菌株组合的促生效果最好,其核心菌株为芽孢杆菌(Bacillus sp.)Ia-14、黄色假杜擀氏菌(Pseudoduganella flava)ASD1-2、假单胞菌(Pseudomonas sp.)SC1-7和水稻节杆菌(Arthrobacter oryzae)PaS-6-2。【结论】梭梭根际及内生促生菌资源丰富,其主要通过固氮、解磷、解钾、产铁载体、产IAA和产生物膜来发挥对梭梭幼苗的促生作用。芽孢杆菌属(Bacillus)、黄色假杜擀氏菌(Pseudoduganella flava)、假单胞菌属(Pseudomonas)、水稻节杆菌(Arthrobacter oryzae)在促生人工复合菌群中起核心作用。 展开更多
关键词 梭梭 根际促生细菌 内生促生细菌 分离鉴定 人工复合菌群
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贝莱斯芽孢杆菌复配种衣剂研制及对辣椒青枯病的防效 认领 引用 被引量：3
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作者 陈佳伟 林艳 +6 位作者 张明星 邓辉 陶禹 彭迪 周池 李鑫 饶力群 《农药》 CAS CSCD 北大核心 2026年第3期174-185,共12页
[目的]制备稳定高效的生物种衣剂,为辣椒青枯病的绿色防控提供理论和技术支持。[方法]选用功能互补的内生贝莱斯芽孢杆菌(XZT173与FQ127)复配发酵液为主要有效成分,评估不同助剂与贝莱斯芽孢杆菌的生物相容性及理化性能,筛选并优化助剂... [目的]制备稳定高效的生物种衣剂,为辣椒青枯病的绿色防控提供理论和技术支持。[方法]选用功能互补的内生贝莱斯芽孢杆菌(XZT173与FQ127)复配发酵液为主要有效成分,评估不同助剂与贝莱斯芽孢杆菌的生物相容性及理化性能,筛选并优化助剂种类及用量,同时以辣椒作为靶标植物,测定其防治辣椒青枯病效果。[结果]5株贝莱斯芽孢杆菌中,菌株XZT173与FQ127产铁载体、产表面活性素能力和酶活能力(淀粉酶、蛋白酶、纤维素酶)均更强。XZT173与FQ127复配种衣剂助剂筛选中,确定最佳助剂组成为(以质量分数计):木质素磺酸钠(润湿分散剂)2%,壳聚糖(成膜剂)5%,2%海藻酸钠悬浮液(增稠剂)6%,丙三醇(防冻剂)5%,卡松(防腐剂)0.08%,颜料红(警戒色)1.2%。该配方在药种比1∶60的条件下应用效果最佳。与对照(CK)相比,使用贝莱斯芽孢杆菌种衣剂包衣(T1)后,辣椒出苗率提高14%,根系中青枯菌定殖率降低77.57%,病情指数降低25.45%,防治效果达62.42%。[结论]贝莱斯芽孢杆菌种衣剂对辣椒青枯病具有较好的防治效果,具有进一步开发和利用的潜力。 展开更多
关键词 贝莱斯芽孢杆菌 种衣剂 辣椒青枯病 生物防治
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酸枣仁汤调控慢性睡眠剥夺大鼠脑微区空间代谢网络作用研究 认领 引用 被引量：1
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作者 闫艳 孙亚禹 +3 位作者 陶宇 刘嘉颖 杜晨晖 张瑞平 《世界科学技术-中医药现代化》 CSCD 北大核心 2026年第5期1377-1389,共13页
目的利用质谱成像(Massspectrometry imaging,MSI)技术原位可视化与代谢组学技术的数据降维特点,揭示酸枣仁汤(Suanzaoren Decoction,SZRD)调控睡眠剥夺大鼠脑微区空间代谢网络而发挥抗失眠伴焦虑样的作用机制。方法制备改良多平台水环... 目的利用质谱成像(Massspectrometry imaging,MSI)技术原位可视化与代谢组学技术的数据降维特点,揭示酸枣仁汤(Suanzaoren Decoction,SZRD)调控睡眠剥夺大鼠脑微区空间代谢网络而发挥抗失眠伴焦虑样的作用机制。方法制备改良多平台水环境睡眠剥夺大鼠模型,通过高架十字迷宫实验以及血清皮质酮水平评价及SZRD的药效作用;利用质谱成像技术,观察睡眠剥夺大鼠脑中小分子代谢物的原位表达以及变化趋势,探究SZRD的作用特点。结果正常大鼠改良多平台法剥夺21天后,出现焦虑样行为。与模型组比,SZRD显著增加了大鼠进入开臂的时间比例以及次数(P<0.05),降低了血清皮质酮含量(P<0.01),显著改善了睡眠剥夺大鼠的失眠和焦虑样行为。MSI结果显示,慢性睡眠剥夺显著影响了大鼠海马、下丘脑、纹状体和皮层中神经递质及其代谢物的含量;SZRD显著回调了脑内34种差异代谢物含量,主要包括氨基酸类及其代谢产物等。通路分析提示SZRD可能通过调控组氨酸代谢,丙氨酸、天冬氨酸与谷氨酸代谢,以及色氨酸代谢、酪氨酸代谢、精氨酸代谢通路而发挥作用。结论SZRD通过脑中调控色氨酸、酪氨酸等小分子氨基酸的代谢通路以及脑中神经递质的含量以及空间位置分布发挥抗失眠伴焦虑的作用。研究结果为SZRD精准用药,多靶点改善睡眠障碍的作用特点提供了科学依据。 展开更多
关键词 酸枣仁汤 睡眠剥夺 质谱成像 空间代谢组学 氨基酸代谢
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微生物学实验课程思政育人路径的探索 认领 引用 被引量：1
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作者 孟建宇 唐凯 +3 位作者 陶羽 李蘅 冯福应 杨丽华 《中国细胞生物学学报》 CAS CSCD 2026年第6期1610-1618,共9页
在大思政观教育的背景下,专业实践课程与思政元素的融合是落实立德树人根本任务的重要路径,而微生物学实验作为高校生命科学类专业的基础实践课程,本身就有技能培养与价值引领的双重功能。因此,课程团队针对当前微生物学实验课程思政建... 在大思政观教育的背景下,专业实践课程与思政元素的融合是落实立德树人根本任务的重要路径,而微生物学实验作为高校生命科学类专业的基础实践课程,本身就有技能培养与价值引领的双重功能。因此,课程团队针对当前微生物学实验课程思政建设中所暴露出的问题进行了系统改革,通过重构课程目标、建立思政元素矩阵、创新教学模式和完善评价体系,构建了全方位、全过程的实践课程思政育人模式。实践结果表明,教学改革显著增强了学生的科学精神、职业素养和家国情怀,切实提高了学生的实验操作规范性与科研创新能力。该研究为理工科实验课程的思政建设提供了可借鉴的实践模式,对培养德才兼备的高素质生命科学人才具有重要意义。 展开更多
关键词 微生物学实验 课程思政 教学改革 育人路径 评价体系
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A Study on the Skincare Efficacy of Paeonia suffruticosa Root Bark Extract 认领 引用
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作者 Wu Zhensheng Sun Rui +3 位作者 Tian Jianwei Tao Yu Ma Kang Wang Ling 《China Detergent & Cosmetics》 CAS 2026年第1期10-17,共8页
Peony root bark extract as was used the research object,and used a series of biochemical and cellular experiments to investigate its whitening,anti-inflammatory,oil control,acne,and inhibition of the growth of Malasse... Peony root bark extract as was used the research object,and used a series of biochemical and cellular experiments to investigate its whitening,anti-inflammatory,oil control,acne,and inhibition of the growth of Malassezia.The results showed that the inhibition rate of melanin synthesis was significantly increased to 86.43%at a concentration of 2.0%;the secretion of inflammatory factors IL-1αand IL-6 by macrophages(RAW264.7)was significantly reduced to 4.94 pg/mL and 6.42 pg/mL,respectively;the fluorescence signal of Nile red in sebaceous gland cells(SZ95)was significantly reduced to 57.5%;the inhibition rate of Propionibacterium acnes was 37.7%for 20 min of action;and the average inhibition rate of Malassezia marcescens was 78.1%for 20 min of action.Thus,it can be seen that the peony root bark extract has multiple skin-care effects and is a natural and healthy cosmetic plant raw material,which provides a solid theoretical basis for its application in cosmetics. 展开更多
关键词 peony root bark extract whitening soothing oil control acne anti-bacteria
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