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Commemoration of the 100 Birthday of Academician Zhicen Lou——A poem in memory of Academician Zhicen Lou by Alumnus Wei Zhang 认领 引用
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作者 Wei Zhang 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2020年第11期828-828,共1页
为纪念楼之岑院士诞辰100周年,根据古诗句赋藏头诗一首:纪行文字遍长亭,念君长作万里行。楼角渐移当路影,之子别离生药情。岑傍松杉绿莹莹,院中灯火夜通明。士子报国慰英灵,诞辰吉日天开晴。辰良景暮风波静,百花深处杜鹃鸣。周回云水游... 为纪念楼之岑院士诞辰100周年,根据古诗句赋藏头诗一首:纪行文字遍长亭,念君长作万里行。楼角渐移当路影,之子别离生药情。岑傍松杉绿莹莹,院中灯火夜通明。士子报国慰英灵,诞辰吉日天开晴。辰良景暮风波静,百花深处杜鹃鸣。周回云水游丹景,年少不禁随尔行。 展开更多
关键词 藏头诗 楼之岑 诞辰100周年 院士
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A lightweight two-stage physics-informed neural network for SOH estimation of lithium-ion batteries with different chemistries 认领 引用 被引量：3
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作者 Chunsong Lin Longxing Wu +4 位作者 Xianguo Tuo Chunhui Liu Wei Zhang Zebo Huang Guiyu Zhang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2025年第6期261-279,I0007,共19页
Accurately estimating the battery state of health(SOH)is essential for ensuring the safe and reliable operation of battery systems of electric vehicles.However,due to the complex and variable operating conditions enco... Accurately estimating the battery state of health(SOH)is essential for ensuring the safe and reliable operation of battery systems of electric vehicles.However,due to the complex and variable operating conditions encountered in practical applications,achieving precise and physics-informed SOH estimation remains challenging.To address these problems,this paper develops a lightweight two-stage physicsinformed neural network(TSPINN)method for SOH estimation of lithium-ion batteries with different chemistries.Specifically,this paper utilizes firstly relaxation voltage data obtained after a full charge to determine the aging-related parameters of physical equivalent circuit model(ECM).Additionally,incremental capacity(IC)feature is extracted by analyzing peak values of the IC curve during the charging phase,which thereby constitutes the first stage of the proposed TSPINN,termed as physics-informed data augmentation for SOH estimation.Additionally,the physical information can be further embedded by incorporating feature knowledge related to mechanisms into the loss function,and ultimately,the second stage of the proposed TSPINN is developed,which is named the physics-informed loss function.The effectiveness of the TSPINN method was confirmed through the experimental data for LiNi0.86Co0.11Al0.03O2(NCA)and LiNi0.83Co0.11Mn0.07O2(NCM)battery materials under different temperature conditions.The final experimental results indicate that the TSPINN method achieved SOH estimation with a mean absolute error(MAE)of 0.675%,showing improvements of approximately 29.3%,60.3%,and 8.1% compared to methods using only ECM,IC,and integrated features,respectively.The results validate the effectiveness and adaptability of TSPINN,establishing it as a reliable solution for advanced battery management systems. 展开更多
关键词 Lithium-ion battery Voltage relaxation Physics-information neural network Stateof health
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Variations and major driving factors for soil nutrients in a typical karst region in Southwest China 认领 引用 被引量：2
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作者 Miaomiao Wang Hongsong Chen +1 位作者 Wei Zhang Kelin Wang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2026年第2期424-435,共12页
Understanding the spatial distributions and corresponding variation mechanisms of key soil nutrients in fragile karst ecosystems can assist in promoting sustainable development.However,due to the implementation of eco... Understanding the spatial distributions and corresponding variation mechanisms of key soil nutrients in fragile karst ecosystems can assist in promoting sustainable development.However,due to the implementation of ecological restoration initiatives such as land-use conversions,novel changes in the spatial characteristics of soil nutrients remain unknown.To address this gap,we explored nutrient variations and the drivers of the variation in the 0–15 cm topsoil layer using a regional-scale sampling method in a typical karst area in northwest Guangxi Zhuang Autonomous Region,Southwest China.Descriptive statistics,geostatistics,and spatial analysis were used to assess the soil nutrient variability.The results indicated that soil organic carbon(SOC),total nitrogen(TN),total phosphorus(TP),and total potassium(TK)concentrations showed moderate variations,with coefficients of variance being 0.60,0.60,0.71,and 0.72,respectively.Moreover,they demonstrated positive spatial autocorrelations,with global Moran's indices being 0.68,0.77,0.64,and 0.68,respectively.However,local Moran's index values were low,indicating large spatial variations in soil nutrients.The best-fitting semi-variogram models for SOC,TN,TP,and TK concentrations were spherical,Gaussian,exponential,and exponential,respectively.According to the classification criteria of the Second National Soil Census in China,SOC and TN concentrations were relatively sufficient,with the proportions of rich and very rich levels being up to 90.9 and 96.0%,respectively.TP concentration was in the mediumdeficient level,with the areas of medium and deficient levels accounting for 33.7 and 30.1%of the total,respectively.TK concentration was deficient,with the cumulative area of extremely deficient,very deficient,and deficient levels accounting for 87.6%of the total area.Consequently,the terrestrial ecosystems in the study area were more vulnerable to soil P and K than soil N deficiencies.Furthermore,variance partitioning analysis of the influencing factors showed that,except for the interactions,the single effect of other soil properties accounted more for soil nutrient variations than spatial and environmental variables.These results will aid in the future management of terrestrial ecosystems. 展开更多
关键词 dominant factor geostatistics karst ecosystem soil nutrient classification spatial variation
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Restoration boosts soil P-cycle multifunctionality in karst ecosystems by modulating soil properties and rare bacterial taxa 认领 引用 被引量：1
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作者 Fujing Pan Xuan Yu +4 位作者 Yueming Liang Peilei Hu Kelin Wang Wei Zhang Qian Yang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2026年第2期513-528,共16页
Phosphorus (P) is an essential nutrient element that is critical for plant growth and ecosystem functionality.The soil P cycle plays multiple roles,such as sustaining plant growth and productivity,regulating nutrient ... Phosphorus (P) is an essential nutrient element that is critical for plant growth and ecosystem functionality.The soil P cycle plays multiple roles,such as sustaining plant growth and productivity,regulating nutrient balance within ecosystems,and enhancing ecosystem adaptability and resilience.This cycle is influenced by factors such as the restoration approach and microbial community dynamics.However,the extent to which the restoration approach alters the P cycle in karst ecosystems and the underlying microbial mechanisms remain poorly understood.The P-cycle multifunctionality index (P-cycle MFI) serves as a comprehensive indicator for evaluating soil P cycle function,and it provides insights into changes in the P cycle between different restoration approaches.To investigate the shifts in soil P-cycle MFI and microbial mechanisms between different restoration approaches,we analyzed soil available P (AP),total P (TP),microbial biomass P (MBP),and the activities of acid phosphatase (ACP) and alkaline phosphatase (ALP).These data were used to calculate the P-cycle MFI by averaging the Z-scores between two restoration approaches(artificial restoration of forest (AF) and natural restoration of forest (NF)) and a control (cropland,CP) at six subtropical karst ecosystem sites in China.We also determined the soil organic carbon (SOC),exchangeable calcium (Ca) and magnesium (Mg),pH,bulk density (BD),microbial biomass C (MBC),and microbial biomass nitrogen (MBN),as well as the community structure,relative abundance,diversity indices,and co-occurrence networks of phoD-harboring bacteria.The results showed that the community structure of phoD-harboring bacteria varied significantly among AF,NF,and CP and across different temperature gradients.These bacteria exhibited increasing complexity and tightness in co-occurrence networks from CP to AF and then to NF,along with the ACP and ALP activities,but not the TP and AP contents.The P-cycle MFI values were significantly higher in NF compared to AF and CP,and the variation was significantly explained by restoration approach,temperature,MBC,MBN,SOC,exchangeable Ca,BD,community structure of phoD-harboring bacteria,and exchangeable Mg.Furthermore,natural restoration had a more substantial impact on the P-cycle MFI than temperature by enhancing SOC,microbial biomass,the complexity and co-occurrence network tightness of the phoD-harboring bacterial community structure,and ACP and ALP activities,but it reduced soil BD.The rare genera of phoD-harboring bacteria significantly influenced the variation of soil P-cycle MFI compared to the dominant genera.This study highlights the importance of rare genera of phoD-harboring bacteria in driving soil P-cycle multifunctionality in karst ecosystems,with natural restoration being more effective than artificial methods for enhancing soil organic matter and microbial community complexity. 展开更多
关键词 karst ecosystem restoration community phoD-harboring bacteria P-cycle multifunctionality rare taxa
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Prospect in Alzheimer's disease integrative therapy targeting both amyloid-beta and tau 认领 引用 被引量：1
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作者 Wei Zhang Yiqun Zhou +3 位作者 Jiuyan Chen Miranda Perez Xiomara Claure Roger M.Leblanc 《Neural Regeneration Research》 SCIE CAS CSCD 2026年第10期4798-4802,共5页
Alzheimer's disease is well characterized by the buildup of amyloid-β plaques and tau protein tangles,leading to neurodegeneration and cognitive impairments.Recent prosperous Alzheimer's disease therapeutic d... Alzheimer's disease is well characterized by the buildup of amyloid-β plaques and tau protein tangles,leading to neurodegeneration and cognitive impairments.Recent prosperous Alzheimer's disease therapeutic development targeting amyloid-β validates the amyloid hypothesis.Nonetheless,the limited efficacy of single-target therapies plus as-observed synergy between amyloid-β and tau calls for a thorough understanding of Alzheimer's disease pathogenesis.Thus,this review introduces Alzheimer's disease pathogenesis,specifically focusing on the amyloid-β and tau pathologies,highlights their interconnected nature,presents personal perspectives on therapeutic and diagnostic challenges,and underscores the necessity of combined therapeutic approaches to effectively address Alzheimer's disease. 展开更多
关键词 Alzheimer’s disease amyloid-β integrative therapy interplay multi-target therapy tau
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Ferroptosis involved in inhaled polystyrene microplastics leaded myocardial fibrosis through HIF-ROS-SLC7A11/GPX4 Pathway 认领 引用 被引量：1
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作者 Danyang Huang Huiwen Kang +5 位作者 Ziyan Liu Wei Zhang Jingyu Wang Ziyan Wang Guangyu Jiang Ai Gao 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第1期391-402,共12页
The issue of microplastic(MPs)pollution has received increased attention in recent years.Studies have indicated that inhalation of microplastics may result in the cardiovascular harm.However,the specific mechanism rem... The issue of microplastic(MPs)pollution has received increased attention in recent years.Studies have indicated that inhalation of microplastics may result in the cardiovascular harm.However,the specific mechanism remains to be elucidated.In this study,5μm polystyrene microplastics(PS-MPs)were employed to construct in vivo and in vitro exposure models to investigate the potential mechanisms of microplastic-induced cardiac fibrosis.In vivo model of respiratory exposure to MPs,echocardiography observed a decrease in systolic-diastolic function of the mouse heart,and myocardial tissue showed significant mitochondrial morphological abnormalities and myocardial fibrosis.In vitro models also revealed upregulation of fibrosis indicators in human cardiomyocytes AC16 cells.Transcriptome and RT-qPCR assay exposed that ferroptosis-related pathways were significantly gath-ered in the MPs group,with decreased expression of ferroptosis related genes SLC7A11 and GPX4.Liproxstatin-1(Lip-1),a ferroptosis inhibitor,significantly ameliorated MPs-induced cardiomyocyte fibrosis and ferroptosis.We further demonstrated that inhibition of hypoxia-inducible factor?(HIF-?)and oxidative stress ameliorated PS-MPs-induced cardiomyocyte ferroptosis,and thus upregulation of the HIF pathway and oxidative stress may be the upstream mechanism of MPs-induced ferroptosis in myocardial fibrosis.Above all,our study demonstrated that MPs exposure resulted in cardiac fibrosis via the HIF-ROS-SLC7A11/GPX4 signaling pathway. 展开更多
关键词 Polystyrene Microplastics Inhale Ferroptosis Cardiotoxicity
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Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis 认领 引用 被引量：1
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作者 Ze-Xi Jia Meng-Tian Guo +11 位作者 Mei-Mei Li Pan Liao Bo Yan Wei Zhang Fang-Yuan Cheng Ya-Ru Liu Zi-Han Zhang Cheng Wei Jie Zhou Fang-Lian Chen Ping Lei Xin-Tong Ge 《Military Medical Research》 SCIE CAS CSCD 2026年第1期24-42,共19页
Background:Repetitive mild traumatic brain injury(rmTBI)is a significant risk factor for neurodegeneration,characterized by pathological protein deposition and persistent neuroinflammation.Research has observed increa... Background:Repetitive mild traumatic brain injury(rmTBI)is a significant risk factor for neurodegeneration,characterized by pathological protein deposition and persistent neuroinflammation.Research has observed increased interleukin-33(IL-33)levels in the peripheral blood of patients with rmTBI,suggesting IL-33 may participate in regulating the pathological development of rmTBI.The study aims to elucidate the impact and mechanism of IL-33 in the progression of neuropathology following rmTBI,and to explore its potential as a therapeutic target to improve the neurological outcome.Methods:The study employed an rmTBI mouse model using the wild-type(WT)and IL-33 knockout mice.Cognitive function was assessed via the Y-maze and Barnes tests.The main cell type expressing IL-33 and its receptor,suppression of tumorigenicity 2(ST2),was then investigated in the mouse brain through immunofluorescence colocalization.As the primary neural cell responsible for ST2 expression,microglia were studied in vitro using the BV2 cell line.The effects of lipid droplets(LDs)accumulation and amyloid-beta(Aβ)phagocytosis were measured to elucidate the impact of IL-33 on BV2 cells'phagocytosis.Additionally,HT22 neuronal apoptosis was assessed by flow cytometry.Finally,the cognitive effects of intranasal administration of IL-33 were evaluated in mice.Results:IL-33 KO mice exhibited pronounced cognitive impairment after rmTBI.In the mouse brain,astrocytes were identified as the primary source of IL-33 secretion,while microglia predominantly expressed ST2.Transcriptome sequencing revealed that IL-33 significantly influenced phagocytosis function.IL-33 mitigated LDs accumulation in BV2 cells and enhanced Aβphagocytosis in vitro.In addition,the culture medium of BV2 cells with activated IL-33/ST2 signaling reduced HT22 neuronal apoptosis and axonal damage.Furthermore,intranasal administration of IL-33 was observed to be effective in alleviating neurodegeneration and cognitive outcome of rmTBI mice.Conclusions:Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage.IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI. 展开更多
关键词 Repetitive mild traumatic brain injury(rmTBI) Interleukin-33(IL-33) Microglia Cognition
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Author Correction:Rescuing fertility:C-Phycocyanin prevents ovarian damage through NRF2-mediated ferroptosis pathways in polycystic ovary syndrome models 认领 引用
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作者 Jing Zhang Qun-Shan Shen +8 位作者 Ya-Xin Chen Hui-Ru Cheng Wei Zhang Ting Xing Ya-Jing Liu Yun-Xia Cao Dan Liang Man Luo Biao Yu 《Zoological Research》 SCIE CSCD 2026年第2期374-374,共1页
Following the publication of the article by Zhang et al.(2025),inadvertent errors were identified during figure preparation.Specifically,in Figures 3E and 6F,both representing the Control group,an assembly error resul... Following the publication of the article by Zhang et al.(2025),inadvertent errors were identified during figure preparation.Specifically,in Figures 3E and 6F,both representing the Control group,an assembly error resulted in the repeated use of the same Control images.In addition,in Figure 4C,an image pasting error occurred in which data from the Control group were mistakenly placed into the DHEA+C-PC treatment group.To ensure the accuracy and integrity of our published work,we formally request a correction to address these issues and sincerely apologize for any confusion they may have caused.The revised Figures 4 and 6 are provided in the updated Supplementary Materials. 展开更多
关键词 c phycocyanin image pasting error rescue fertility ferroptosis polycystic ovary syndrome nrf figure preparationspecificallyin ovarian damage
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Physical characteristics,thermal structure,geothermal and carbon emission reduction potential of typical basins in Eastern China 认领 引用
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作者 Feng Ma Gui-ling Wang +4 位作者 Wei Zhang Xi Zhu Hao-nan Gan Guang-zhen Jiang Chen Luo 《China Geology》 CAS CSCD 2026年第1期195-213,共19页
The geothermal resources in China are primarily found in its sedimentary basins,particularly in the large basins located in eastern China,which hold significant potential for geothermal energy development.The Songliao... The geothermal resources in China are primarily found in its sedimentary basins,particularly in the large basins located in eastern China,which hold significant potential for geothermal energy development.The Songliao,North China,and Zhangzhou basins are of special interest due to their considerable exploration depths,extensive development history,and high levels of research activity.This study focuses on the three basins to analyze their thermal reservoir characteristics in eastern China.Between 2017 and 2023,the research team carried out a comprehensive analysis involving deep boreholes that exceeded 4000 m in depth within these three basins.They meticulously created detailed physical profiles that captured essential characteristics such as porosity,permeability,and thermal properties,reaching down to the basement of each basin.The findings indicated that variations in thermal conductivity within shallow geotechnical layers significantly influence the redistribution of deep thermal energy in the upper layers of the earth.Furthermore,differences in physical properties notably affect heat transport processes.The research proposes distinct heat models tailored for each basin:For the Songliao Basin,a low-permeability model with homogeneous thermal properties is constructed;for the North China Basin,high permeability and thermal conductivity layers are highlighted;and a fracture network controlling water and heat is presented in the Zhangzhou Basin.To elucidate the thermal structure of these basins,the Curie surface and Moho surface were analyzed.The shallow Curie surface indicates ongoing intense thermal activity stemming from crustal heat sources,while a shallow Moho surface signifies historical vigorous mantle thermal activity associated with mantle source heat production.Furthermore,the research evaluates the geothermal resources and the potential for carbon emission reduction in these basins.Total volume of exploitable geothermal fluid is estimated to be 76.9×109 m3/a,corresponding to an annual renewable geothermal energy 1.47×1016k J.The implementation of geothermal energy could lead to a reduction in annual CO2emissions by nearly 2×109 t,which constitutes about 17.4%of China’s national carbon emissions in 2022.This estimation provides invaluable theoretical insights and data support for geothermal exploration and sustainable development in eastern China. 展开更多
关键词 Geothermal energy Sedimentary basin type Clean energy Geophysical properties Thermal conductivity Heat generation rate Power generation Heating in winter Carbon emission reduction Geological survey engineering Resource evaluation
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Dual-zeolite relay catalysis for synthesis of light aromatics from CO2hydrogenation 认领 引用
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作者 Jingming Zhao Wei Zhang +8 位作者 Kai Wang Yang Yu Dingjun Hu Qi Gao Aimin Wang Lin Lang Qingjie Ge Jian Wei Jian Sun 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第7期618-630,I0015,共13页
The direct conversion of carbon dioxide(CO2)to light aromatics(benzene,toluene,and xylene,BTX)remains challenging due to low selectivity and heavy aromatic formation.Herein,a dual-zeolite relay catalytic strategy b... The direct conversion of carbon dioxide(CO2)to light aromatics(benzene,toluene,and xylene,BTX)remains challenging due to low selectivity and heavy aromatic formation.Herein,a dual-zeolite relay catalytic strategy based on a ZnZr/SAPO-34/ZSM-5 system is proposed.An optimized Zn-Zr solid solution with abundant oxygen vacancies(~21%)activates CO2toward methanol formation,while SAPO-34 acts as a molecular editor to convert methanol into light olefins that feed subsequent aromatization over ZSM-5.The matched acidity and close proximity of the dual zeolites enable olefin-mediated aromatization while suppressing paraffin formation.Consequently,the tandem catalyst achieves a total aromatic selectivity of 77.1%at a CO2conversion of 8.6%under optimized conditions(320℃,3.0 MPa).The BTX fraction reaches 40.8%,corresponding to an overall BTX selectivity that is 3.2 times that of ZnZr/ZSM-5.This work demonstrates a general catalyst design paradigm integrating metal oxide engineering with intermediate editing for pathway control in CO2valorization. 展开更多
关键词 CO2hydrogenation Dual-zeolite Tandem catalysts OX-ZEO BTX Aromatics
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Near-perfect optical chirality enabled by gain modulated Born-Kuhn-type metasurfaces 认领 引用
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作者 HAOJIE LI JIAYI ZHANG +9 位作者 GUOXIA YANG XIAOFEI HAN HUIYUAN YU YIHE LI LIPING ZHANG XIAOLU GE BENYI WANG ZHONGSHENG MAN WEI ZHANG JINWEI SHI 《Photonics Research》 SCIE EI CAS CSCD 2026年第6期2532-2540,共9页
Chiral metasurfaces with tailorable chiroptical responses are of great interest for applications in many fields.However,most previous studies on non-Hermitian chiral metasurfaces have focused on the realization of exc... Chiral metasurfaces with tailorable chiroptical responses are of great interest for applications in many fields.However,most previous studies on non-Hermitian chiral metasurfaces have focused on the realization of exceptional points,where the strong circular dichroism(CD)is often accompanied by low transmission.Here,we propose a gain-assisted non-Hermitian approach to achieve near-perfect optical chirality in a Born-Kuhn-type plasmonic metasurface.The structure consists of bilayer,orthogonally oriented silver nanorods integrated with an optical gain medium.Guided by a coupled-oscillator model,we show that the interplay between geometrical chirality and gain-induced non-Hermitian coupling enables precise control of the interlayer interaction and modal hybridization.As a result,a CD value as high as 0.999 is obtained at 1550 nm,while a high transmission of 0.988 for the selected circular polarization is maintained.Furthermore,leveraging the plasmon-enhanced local fields,a pronounced handedness-selective third-harmonic generation response is theoretically demonstrated.This work provides a strategy for high-efficiency chiral photonic devices and opens opportunities for potential applications in chiral molecular detection,ultrasensitive sensing,chiral logic,superchiral fields,and chiral nonlinear optics. 展开更多
关键词 modal hybridization realization exceptional pointswhere chiral metasurfaces circular dichroism circular dichroism cd bilayerorthogonally oriented silver tailorable chiroptical responses gain assisted non hermitian
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Fluorescent probes reveal the differential impact of ferroptosis inhibition on drug-induced liver and kidney injury 认领 引用
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作者 Wei Zhang Lei Yang +4 位作者 Zhihang Jin Shusheng Zhang Fawei Zhu Zhanxian Li Mingming Yu 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第4期603-608,共6页
Ferroptosis has emerged as a significant pathway in various pathological conditions.Studying the effects of inhibiting ferroptosis on liver injury is instrumental in gaining a deeper understanding of the mechanisms.Th... Ferroptosis has emerged as a significant pathway in various pathological conditions.Studying the effects of inhibiting ferroptosis on liver injury is instrumental in gaining a deeper understanding of the mechanisms.This study the design and synthesis of a multi-channel near-infrared emitting fluorescent probe TXVQ.When the probe TXVQ responds to HSO3-,the fluorescence intensity at 500 nm of TXVQ increases with the addition of HSO3-.As the concentration of H2O2 increases,the fluorescence intensity of TXVQ at 600 nm is enhanced.Concurrently,as viscosity rises,the fluorescence intensity of the probe TXVQ at 725 nm will gradually increase.The probe TXVQ,with its ability to monitor HSO3-,H2O2 and viscosity through three distinct fluorescent channels,is advantageous for its application in the biological field.Subsequently,cellular experiments have demonstrated that the probe TXVQ can monitor changes in intracellular HSO3-,H2O2 and viscosity.At the cellular level,it is found that inhibiting ferroptosis had no alleviating effect on drug-induced liver injury(DILI),but it had a certain alleviating effect on acute kidney injury(AKI).In a murine model,the effects of ferroptosis inhibition on DILI and AKI indicate that inhibiting ferroptosis reduced kidney injury but not liver injury,highlighting its potential in kidney therapeutics.TXVQ can detect various levels of HSO3-,H2O2 and viscosity through three different fluorescent channels,making it a powerful tool for diagnosing and treating kidney diseases,as well as deepening the understanding of the role of ferroptosis in liver and kidney pathologies. 展开更多
关键词 Ferroptosis inhibition Drug-induced liver injury Kidney injury HSO3- H2O2 Viscosity
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Multi-source hydrocarbon accumulation in the faulted and deeply depressed Tangdong area,Qikou Sag,Bohai Bay Basin 认领 引用
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作者 Xiugang Pu Guochao Xia +6 位作者 Jiangchang Dong Zhannan Shi Wenzhong Han Qianru Shi Wei Zhang Yueqi Dong Xiongying Dong 《Energy Geoscience》 EI CAS CSCD 2026年第2期85-100,共16页
Based on organic geochemical analysis data,this study examined the characteristics of multi-source hydrocarbon accumulation in the Tangdong area of Qikou Depression,Bohai Bay Basin.The results indicate that the Tangdo... Based on organic geochemical analysis data,this study examined the characteristics of multi-source hydrocarbon accumulation in the Tangdong area of Qikou Depression,Bohai Bay Basin.The results indicate that the Tangdong area contains four source rock sequences:the third member of the Dongying Formation(Ed3),the middle and lower sub-members of the first and third member of Shahejie Formation(Es 1M,Es 1L,Es 3).Both the salinity of sedimentary water bodies and the contribution of bacteria in the four source rock sequences gradual increase in the order of Es 3,Es 1M,Es 1L and Ed3,as indicated by the Ga/C30H,ETR,sterane/C30 hopane,C24TeT/C26TT,C23TT/C30H,and the carbon isotope data of group components.Additionally,certain quantities of 4-methylsterane have been detected in source rocks in the Es 3,Es 1M,and Ed3,suggesting the special contribution of dinoflagellates to these source rocks.Based on biomarker parameters and carbon isotope data,the crude oil can be categorized into classes A to D,which show complex multi-source accumulation characterized by different sources in the same well and even in the same layer.Class A crude oil occurring in the higher part of the Ed3 originates from source rocks in the Es 1L and Es 3.Class B oil existing in the lower part of the Ed3 is derived from source rocks in the Ed3.Class C oil found in the Es 1U is sourced from source rocks in the Es 1M.Class D oil present in the Es 1L is contributed indigenously by the source rocks in the Es 1L,establishing this unit as a lithologic hydrocarbon reservoir with source rocks and reservoirs in the same layer.Under the guidance of the understanding of multi-source hydrocarbon accumulation,currently,three wells have been drilled,all yielding satisfactory outcomes. 展开更多
关键词 Oil-source rock correlation Multi-source hydrocarbon accumulation Petroleum geochemistry Source rock Deeply depressed area Qikou sag Exploration well emplacement
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Multi-scale interfacial mechanisms of Pb immobilization in contaminated soil using phosphoric acid-activated coal gangue-electrolytic manganese residue geopolymers 认领 引用
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作者 Wei Zhang Lei Lang +4 位作者 Zhen Qi Ping Wang Qiang Xue Fangqin Cheng Jiangshan Li 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第3期2266-2287,共22页
The accumulation of contaminated soils and solid waste stockpiles has led to significant resource wastage and environmental pollution.This study investigates a novel solidification/stabilization(S/S)curing agent,named... The accumulation of contaminated soils and solid waste stockpiles has led to significant resource wastage and environmental pollution.This study investigates a novel solidification/stabilization(S/S)curing agent,named ECPG,synthesized from electrolytic manganese residue(EMR),coal gangue(CG),and phosphoric acid,for the treatment of Pb-contaminated soils.The influences of ECPG dosages,CG to EMR ratios,Pb2+and phosphoric acid concentrations,curing age,and durability on the strength development and leaching characteristics of the solidified soils were systematically investigated.Durability tests under different freeze-thaw and wet-dry cycles were also conducted to assess long-term performance.The mechanisms of geopolymerization,S/S,and strength enhancement were elucidated through tests and molecular simulations.The results demonstrated that the optimal CG to EMR ratio was 8:2 with 7 mol/L phosphoric acid,resulting in a peak strength of 5.9 MPa and immobilization rates of 99.7%,99.3%,and 81.5%for Pb,Mn,and NH4+-N after curing for 28 d.Freeze-thaw and wet-dry cycles demonstrated excellent durability,with unconfined compressive strength(UCS)above 85%and Pb leaching value of 0.42 mg/L.Molecular simulations revealed that Pb and Mn were primarily immobilized by adsorption,with ion exchange serving as a secondary mechanism,and a minor fraction resulted in the formation of phosphate precipitates.Conversely,NH4+-N was predominantly immobilized via ion exchange,with a portion forming MgNH4PO4·6H2O and MnNH4PO4·H2O.This study can not only contribute to the advancement of safe disposal and resource reuse of contaminated soil and solid waste,but also offers a theoretical foundation for S/S technology from a multi-scale perspective. 展开更多
关键词 Pb-contaminated soil Electrolytic Manganese Residue(EMR) Coal Gangue(CG) Solidification/Stabilization(S/S) Muti-scale Molecular simulations
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Enhancing irradiation tolerance of Mg-Mn based alloys via tailoring Mn nanoprecipitates 认领 引用
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作者 Wei Zhang Zhipeng Shen +7 位作者 Hucheng Pan Jiaying Wu Tong Fu Dongsheng Xie Aitao Tang Changqing Teng Lu Wu Gaowu Qin 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2026年第4期370-382,共13页
Magnesium alloys act as potential candidate nuclear materials due to their excellent chemical compatibility and neutron economy.In this work,the irradiation behavior of pure Mg,Mg-3Mn and Mg-3Mn-0.5Ca alloys were stud... Magnesium alloys act as potential candidate nuclear materials due to their excellent chemical compatibility and neutron economy.In this work,the irradiation behavior of pure Mg,Mg-3Mn and Mg-3Mn-0.5Ca alloys were studied via Xe+implantation at room temperature.Transmission electron microscopy(TEM)results show the formation of dislocation loops,Xe bubbles and Mn nanoprecipitates in irradiated Mg samples.For Mg-3Mn alloy,the high density of Mn nanoprecipitates are formed periodically along the basal plane after Xe irradiation.It is noted that these nanoprecipitates could suppress the nucleation and growth of Xe bubbles to reduce the swelling ratio(only,0.011%),which is much less than that of pure Mg.In contrast,the pre-existing Mn particles in the Mg-3Mn-0.5Ca alloy will cause the absence of Mn nanoprecipitates under Xe irradiation.In addition,the irradiation-induced Mn nanoprecipitates could restrict the growth of c-loops and facilitate more c-loops nucleation.Eventually,under the irradiation dose of 9.7 dpa,a high-density c-loop dislocation is formed,with no detectable a-loop formation in the Mg-3Mn sample.The present study could provide a reference for designing the irradiation resistance Mg alloys. 展开更多
关键词 Mg alloys Irradiation damage Swelling Dislocation Precipitation
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Enhancing high volumetric energy density of supercapacitors through diatomic reconstruction of layered double hydroxides 认领 引用
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作者 Rong Zheng Lin Sun +5 位作者 Yi Guo Yu Liu Qingjun Yang Wei Zhang Yulong Ying Weidong Shi 《Green Energy & Environment》 SCIE EI CAS CSCD 2026年第3期736-747,共12页
Double atom regulation and synergistic phosphorus doping and oxygen vacancy(OV)engineering are effective strategies for optimizing the electronic structure of layered double hydroxides(LDHs).In this study,a self-suppo... Double atom regulation and synergistic phosphorus doping and oxygen vacancy(OV)engineering are effective strategies for optimizing the electronic structure of layered double hydroxides(LDHs).In this study,a self-supporting P-doped OV-(Co0.5Ni0.5)3V2O8electrode with interpenetrating carbon nanotube networks was synthesized via cation/anion co-reconstruction.Leveraging vanadium's high valence states,the dual atom system creates a microporous architecture that enables precise charge redistribution,enhancing both electrical conductivity and OH-adsorption capacity.Density functional theory confirms that P-OVsynergy reduces charge transfer resistance while optimizing ion diffusion pathways and charge storage kinetics.The optimized electrode achieves outstanding performance:3807.9 F cm-3volumetric capacitance at 1 A g-1and exceptional cycling stability(100%capacity retention over 10000 cycles).Assembled asymmetric supercapacitors deliver 158.1 Wh L-1energy density at 992 W L-1power density,surpassing most reported LDH-based devices.This dual-atom charge redistribution mechanism establishes a universal paradigm for designing high-capacity electrodes,addressing critical challenges in energy storage materials through simultaneous electronic structure modulation and microstructural stabilization. 展开更多
关键词 Supercapacitor Self-supporting film (Co0.5Ni0.5)3V2O8 Oxygen vacancy Energy density
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Precisely sampling single particles of<0.01 mm on the Moon for atomic-level characterization towards energy storage 认领 引用
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作者 Zhenzhen Zhao Wei Zhang +7 位作者 Wenzhuo Shao Qing Liang Xiujuan Li Shiyao Gao Xinyang Li Kaiyu Yang Mingyang Liu Meng Zou 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第6期747-757,I0018,共11页
We propose a new sampling method for analyzing single sub-10μm debris from the Chang'e-5 lunar soil,integrating non-destructive identification,precise manipulation,and multi-dimensional characterization.It identi... We propose a new sampling method for analyzing single sub-10μm debris from the Chang'e-5 lunar soil,integrating non-destructive identification,precise manipulation,and multi-dimensional characterization.It identified and classified 22 randomly sampled microscopic residual particles,which are often overlooked during sample processing but serve as extended carriers preserving the evolutionary history of their parent particle.Subsequent analysis of four representative particles revealed phases including agglutinates,olivine,clinopyroxene,anorthite,and sulfide.Spectral shifts and broadening in Raman peaks reflect space weathering and impact metamorphism,while the atomic-level lattice expansion in anorthite induced by micrometeorite impacts—providing direct microstructural evidence of lunar impact events.Beyond their genetic significance,the identified mineral phases(e.g.,pyroxene,olivine,anorthite)exhibit promising potential for electrochemical energy storage applications.By systematically linking the composition and distinct phases of lunar soil to their transition metal content(e.g.,Fe,Si),this work establishes a framework for in situ fabrication of high-performance energy storage electrodes.This integrated approach ultimately allows us to summarize the key elements and phases in lunar soil viable for electrode fabrication,outline their purification pathways,and elucidate how the extreme lunar environment may influence both material synthesis and device performance,thereby bridging the gap between microscopic residues and functional macroscopic application. 展开更多
关键词 Chang’e-5 lunar soil Microscopy and microanalysis Space weathering Single particle Energy Storage Moon
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Impact of organic carbon composition on bacterial community assembly in organic and mineral soil layers under phosphorus addition in a Robinia pseudoacacia plantation 认领 引用
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作者 Ahejiang SAILIKE Yujie LIANG +10 位作者 Rong FU Hongjian HAO Rong WANG Ning PENG Shicai LI Zhouchang YU Fangxin ZHENG Wei ZHANG Yangyang LIU Peizhi YANG Zhixin ZHANG 《Pedosphere》 SCIE CAS CSCD 2026年第2期554-567,共14页
Increasing phosphorus(P)inputs significantly affect the nutrient cycle of terrestrial ecosystems.The community structure and assembly processes of soil bacteria,which are the primary participants in nutrient cycling w... Increasing phosphorus(P)inputs significantly affect the nutrient cycle of terrestrial ecosystems.The community structure and assembly processes of soil bacteria,which are the primary participants in nutrient cycling within terrestrial ecosystems,are affected by P inputs.However,the assembly processes and driving mechanisms of soil bacterial communities in artificial forest ecosystems in response to P inputs remain unclear.Therefore,in this study,an experiment was conducted in an artificial Robinia pseudoacacia forest on the Loess Plateau to investigate the effects of P additions(0,0.5,1,2,and 4 g P m-2year-1)on soil organic carbon(SOC)composition,bacterial community characteristics(total,abundant,and rare taxa),and assembly processes in the organic horizon(OH)and mineral horizon(MH).The results showed that P addition significantly changed soil physicochemical properties,such as available P(AP),SOC content,and SOC composition in terms of labile and recalcitrant SOC fractions.The proportion of labile SOC fraction increased in OH and decreased in MH,whereas the recalcitrant SOC fraction showed the opposite trend.In OH,the proportion of eutrophic bacteria increased,whereas the proportion of oligotrophic bacteria decreased.In contrast to those in OH,the changes in eutrophic and oligotrophic bacteria in MH exhibited the opposite trend.The diversity of bacterial communities in OH did not change significantly with increasing P levels.In MH,the diversity of total and rare taxa increased,while the diversity of abundant taxa decreased.Under P addition,the total and rare bacterial taxa showed stochastic assembly,whereas the assembly of abundant taxa shifted from stochastic to deterministic processes in OH and from deterministic to stochastic processes in MH.The partial-least squares path modeling revealed that under P addition,the assembly of total and rare bacterial communities in OH and MH was regulated by AP and labile SOC fraction,respectively.Meanwhile,the assembly of abundant taxa in OH and MH was influenced by labile and recalcitrant SOC fractions,respectively.Our findings highlight the critical role of SOC composition across different bacterial taxa,with abundant taxa exhibiting heightened sensitivity to environmental filtration and the availability of SOC resources.Our study provides new insights into the community assembly and driving mechanisms of soil bacteria in artificial forest soils under P addition. 展开更多
关键词 abundant taxa afforestation artificial forest bacterial community assembly mineral horizon organic horizon rare taxa soil organic C
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Origin and design principles of efficient artificial interface layers:Crystal facets dependent CeO2 interlayer for reversible zinc anode 认领 引用
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作者 Sifan Qiao Xinyan Zhou +4 位作者 Qing Liang Long Chen Fuxi Liu Yong Gao Wei Zhang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第6期376-385,I0010,共10页
Artificial interface layer-aided zinc anodes(AIL@Zn)with simultaneously controllable Zn dendrite growth and corrosion resistance are highly expected to simultaneously achieve both high capacity and cycle stability in ... Artificial interface layer-aided zinc anodes(AIL@Zn)with simultaneously controllable Zn dendrite growth and corrosion resistance are highly expected to simultaneously achieve both high capacity and cycle stability in aqueous zinc ion batteries(AZIBs).However,how the facet effects of the AIL guides the efficient Zn deposition behavior remains an open question.Herein,we devise a facile and scalable hydrothermal approach to synthesize various nanostructured X-CeO2 AILs to coat the Zn anode,ultimately offering an X-CeO2@Zn electrode.Among all X-CeO2@Zn anodes,rod-shaped CeO2 with exposed{110}facets modified Zn anode(R-CeO2@Zn)can effectively inhibit dendrite growth and side reactions,thereby delivering ultrastable durability over 2500 h at 1 mA cm-2/0.5 mAh cm-2and reversibility cycled for 250 h at 84.7%depth of discharge.In addition,MoS2//R-CeO2@Zn full cell delivers a significantly capacity retention rate above 99%after 1000 cycles.The superior performance originates from the exposed{110}facets,which uniquely modulate the binding and diffusion energies of Zn adatoms to promote homogeneous deposition.This work shifts the AIL design principle from mere composition selection to atomic-level facet control,offering a general strategy for next-generation battery electrodes.Additionally,the strategy proposes its extension to other metal-ion battery systems. 展开更多
关键词 Ceria Zn anode Artificial interface layer Exposed facets Design principle
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STING1 negatively regulates translation and replication of foot-and-mouth disease virus independently of interferon and is antagonized by the viral proteins 3C and 2B 认领 引用
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作者 Wenhua Shao Wei Zhang +10 位作者 Zhitong Chen Tingting Zhou Xiaoyi Zhao Hongyi Liu Chuangwei Chen Xingyan Dong Weijun Cao Zongsheng Zhao Fan Yang Zixiang Zhu Haixue Zheng 《Virologica Sinica》 SCIE CAS CSCD 2026年第2期355-370,共16页
Foot-and-mouth disease virus(FMDV),a highly contagious picornavirus,employs multifaceted strategies to evade host innate immunity,with viral proteins 3Cprotease(3Cpro)and 2B serving as key immune antagonists.The... Foot-and-mouth disease virus(FMDV),a highly contagious picornavirus,employs multifaceted strategies to evade host innate immunity,with viral proteins 3Cprotease(3Cpro)and 2B serving as key immune antagonists.The stimulator of interferon genes 1(STING1)is a critical innate immune adaptor;however,its role and regulatory mechanisms during FMDV infection remain incompletely understood.Here,we report that STING1 inhibits FMDV replication through an interferon(IFN)-independent mechanism,while FMDV counteracts this antiviral effect by degrading STING1 via 3Cproand 2B.Mechanistically,FMDV 3Cpromediates STING1 degradation in a protease activity-dependent manner;this STING1-degrading activity is conserved among 3Cproproteins of poliovirus,enterovirus 71,and coxsackievirus,but not senecavirus A.In contrast,FMDV 2B suppresses STING1 expression at the mRNA level,and neither proteasomal,lysosomal,nor caspase pathways are involved in 3Cpro/2B-mediated STING1 downregulation.Furthermore,the STING1 stabilizer SB24011 enhances endogenous STING1 expression,dose-dependently inhibits FMDV replication by targeting viral internal ribosome entry site(IRES)-mediated translation,and exhibits broad-spectrum antiviral activity against multiple picornaviruses.In vivo,SB24011 treatment alleviates virus-induced histopathological lesions.Collectively,our findings reveal a novel IFNindependent antiviral role of STING1 against FMDV,identify 3Cproand 2B as FMDV-encoded STING1 antagonists,and highlight the potential of SB24011 as a broad-spectrum anti-picornavirus therapeutic agent. 展开更多
关键词 Foot-and-mouth disease virus(FMDV) STING1 3Cprotease Interferon-independent Antiviral activity
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