A cost-effective Fe-P-C nanocrystalline alloy(Fe85P_9C_6)was developed via melt-spinning by eliminating expensive alloying elements and post-annealing steps.The microstructure consists of an amorphous matrix with u...A cost-effective Fe-P-C nanocrystalline alloy(Fe85P_9C_6)was developed via melt-spinning by eliminating expensive alloying elements and post-annealing steps.The microstructure consists of an amorphous matrix with uniformly dispersed nanocrystalline clusters,featuring an average size of approximately 5 nm.This dual-phase structure remains thermally stable up to 569 K and results in excellent magnetic and mechanical performance,including a high saturation magnetic induction of 1.69 T,Vickers hardness of 621 HV,and outstanding bending ductility.Crystallization proceeds via the transformation of a metastable fcc-(Fe,P,C)phase intoα-Fe,Fe3C,and Fe3P,driven by internal stress arising from atomic size mismatch.Continuous heating and cooling transformation diagrams further reveal that this process can be precisely controlled to optimize phase evolution.The high Fe content and stress-relaxed nanocrystalline clusters contribute to enhanced in-plane magnetic anisotropy and rapid domain response.This simplified,annealing-free approach not only reduces material and processing costs but also provides a viable pathway for scalable fabrication of next-generation soft magnetic alloys with superior performance and manufacturability.展开更多
Low-temperature reduction degradation(LTRD)has long been regarded as a key metallurgical property of iron ore sinter,which exhibits a significant influence on the stability and efficiency of blast furnace operation.Ho...Low-temperature reduction degradation(LTRD)has long been regarded as a key metallurgical property of iron ore sinter,which exhibits a significant influence on the stability and efficiency of blast furnace operation.However,the reduction behavior of sinter under low-temperature conditions is not yet fully understood.The low-temperature reduction behavior of sinter was investigated.The reduction mechanism of sinter under low-temperature conditions was clarified through characterization methods,including X-ray diffraction,microstructural analysis and energy-dispersive X-ray spectroscopy.An interesting phenomenon was found that the reduction degradation index RDI+3.15 of sinter sharply decreased from 86.05%after reducing for 30 min and to 58.6%for 45 min.The reduction behavior of sinter was further investigated using a thermogravimetric furnace.The results showed that the reduction rate initially reached a peak,followed by a sharp decline to a minimum at approximately 10 min.This decrease occurred as a result of the formation of a reaction product layer,which hindered the diffusion of the reducing gas into the interior of the sinter.Subsequently,the reduction rate increased again,reaching a second peak at approximately 40 min.The increase in reduction rate was attributed to the formation of cracks rather than gas diffusion.It was further determined that the primary cause of LTRD is the volumetric expansion induced by the reduction of surface hematite.Moreover,the low-temperature reduction of sinter involved only the transformation of hematite to magnetite,with the overall reduction degree remaining low at only 6.31%.展开更多
Comprehensive characterization of mammalian gut viromes is essential for early detection of commensal and potentially zoonotic viruses and for reducing the risk of cross-species transmission.Viral metagenomics was app...Comprehensive characterization of mammalian gut viromes is essential for early detection of commensal and potentially zoonotic viruses and for reducing the risk of cross-species transmission.Viral metagenomics was applied to profile gut viral communities from zoo mammals maintained across multiple zoological institutions in China.Viral communities differed markedly among host dietary guilds,with herbivores exhibiting the highest viral species diversity.In total,1027 viral sequences representing five major viral groups were recovered,including multiple mammal-associated astroviruses,picornaviruses,and parvoviruses with potential infectivity.Phylogenetic reconstruction based on viral hallmark genes demonstrated extensive genomic diversification across recovered lineages.Hosts for most microviruses were predicted to belong to the bacterial family Bacteroidaceae.In addition,10 previously unreported crAss-like phages were identified in mammalian samples and showed close evolutionary relationships with proposed crAssphages from the human gut virome.Antibiotic resistance genes identified in the mammalian gut viromes primarily belonged to tetracyclines.These findings substantially expand current understanding of viral community structure in captive animals in China and provide a foundation for proactive surveillance frameworks targeting emerging mammalian viruses with zoonotic potential.展开更多
Tunnel micro-deformation is a progressive mechanical response process of geotechnical media under the influence of stress redistribution,environmental loads,material aging and other factors.Its millimeterlevel dynamic...Tunnel micro-deformation is a progressive mechanical response process of geotechnical media under the influence of stress redistribution,environmental loads,material aging and other factors.Its millimeterlevel dynamic evolution is difcult to eectively capture by traditional monitoring technologies.Based on the physical mechanism of microwave remote sensing,this paper uses Ground-Based Synthetic Aperture Radar(GB-SAR)for continuous,non-contact deformation perception of tunnel structures.The system transmits and receives coherent electromagnetic wave signals,and extracts millimeter-level even sub-millimeter-level deformation information by means of dierential interferometry technology.Combined with typical tunnel engineering cases,the study verifies the monitoring stability and reliability of the system under different geological conditions and complex environments.The results show that the system can realize real-time,highprecision monitoring of the full-section deformation eld of tunnels with high early warning accuracy and strong environmental adaptability,providing an effective geophysical technical means for tunnel structure health diagnosis and safe operation and maintenance.展开更多
BACKGROUND Circulating irisin,a myokine,has been inconsistently associated with prediabetes mellitus(PreDM),and its relationship with glucagon is unexplored.Methodological variability,particularly between different en...BACKGROUND Circulating irisin,a myokine,has been inconsistently associated with prediabetes mellitus(PreDM),and its relationship with glucagon is unexplored.Methodological variability,particularly between different enzyme-linked immunosorbent assay(ELISA)kits,is hypothesized to be a primary source of these discrepancies.Therefore,we hypothesized that the reported irisin-PreDM association is critically confounded by assay methodology and inadequate adjustment for key metabolic factors.AIM To investigate circulating irisin in PreDM via a dual-study approach,evaluating methodological variability and metabolic confounders.METHODS A dual-study design was employed:(1)A systematic review and meta-analysis of observational studies;and(2)A single-center,exploratory case-control study of 35 participants(9 PreDM,26 controls)from a tertiary hospital.Irisin was measured with two commercial ELISA kits(ELK and Elabscience).Key analyses included random-effects meta-analysis,multiple linear regression,Spearman correlation,and Bland-Altman analysis for inter-assay agreement.RESULTS The meta-analysis(8 studies,n=788)found significantly lower irisin in PreDM(standardized mean difference=-0.524,95%confidence interval:-0.897 to-0.152,P=0.006)with high heterogeneity(I2=86.7%).In the case-control study,unadjusted analysis showed higher irisin in PreDM with the Elabscience kit(median:7386.3 pg/mL vs 6332.0 pg/mL,P=0.045)but not the ELK kit.After adjusting for gender,body mass index,and fatty liver,the association was null for both kits.Bland-Altman analysis revealed poor inter-assay agreement(mean bias:5837.25 pg/mL).Irisin correlated with fatty liver(ρ=0.350,P=0.039)and 0.5-hour glucose(ρ=0.421,P=0.012),but not with glucagon.CONCLUSION The irisin-PreDM relationship appears to be influenced by assay methodology and metabolic factors.Standardizing irisin measurement and adjusting for key confounders are important considerations for future research.展开更多
BACKGROUND Anal fistula is a common anorectal disorder for which conventional surgical procedures often result in relatively high recurrence and complication rates.Ligation of the intersphincteric fistula tract(LIFT),...BACKGROUND Anal fistula is a common anorectal disorder for which conventional surgical procedures often result in relatively high recurrence and complication rates.Ligation of the intersphincteric fistula tract(LIFT),a sphincter-preserving technique,has emerged as a potential alternative.AIM To systematically evaluate and compare the clinical efficacy,safety,and postoperative outcomes of LIFT vs conventional surgical approaches in the management of anal fistula using evidence from randomized controlled trials(RCTs).METHODS In accordance with Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines,we conducted a comprehensive systematic search of both Chinese and international databases to identify RCTs published during January 2014 to 2025.Studies were deemed eligible if they directly compared LIFT with conventional surgical approaches,such as seton placement,fistulotomy,and fistulectomy.The extracted data were analyzed using Review Manager;the methodological quality of the included trials was rigorously evaluated by using the Cochrane risk-of-bias tool.RESULTS In total,107 RCTs involving 9401 participants met the inclusion criteria.LIFT yielded higher healing rates and significantly lower recurrence and complication rates than conventional surgery.Patients undergoing LIFT reported a lower postoperative pain,shorter woundhealing duration,and better preservation of the anal sphincter function.No significant difference was recorded in the operative time between the two groups.CONCLUSION The LIFT procedure demonstrated clear advantages over conventional surgical methods in terms of clinical efficacy,safety,and postoperative recovery,supporting the former’s role as an effective and sphincter-preserving treatment for anal fistula.Nevertheless,most available trials are limited by short follow-up durations and heterogeneous outcome definitions,underscoring the need for undertaking large,multicenter RCTs employing standardized endpoints.展开更多
With the increasing demand for energy,traditional oil resources are facing depletion and insufficient supply.Many countries are rapidly turning to the development of unconventional oil and gas resources.Among them,sha...With the increasing demand for energy,traditional oil resources are facing depletion and insufficient supply.Many countries are rapidly turning to the development of unconventional oil and gas resources.Among them,shale oil and gas reservoirs have become the focus of unconventional oil and gas resources exploration and development.Based on the characteristics of shale oil and gas reservoirs,supercritical CO2 fracturing is more conducive to improving oil recovery than other fracturing technologies.In this paper,the mechanism of fracture initiation and propagation of supercritical CO2 in shale is analyzed,including viscosity effect,surface tension effect,permeation diffusion effect of supercritical CO2,and dissolution-adsorption effect between CO2 and shale.The effects of natural factors,such as shale properties,bedding plane and natural fractures,and controllable factors,proppant,temperature,pressure,CO2 concentration and injection rate on fracture initiation and propagation are clarified.The methods of supercritical CO2 fracturing process,thickener and proppant optimization to improve the efficiency of supercritical CO2 fracturing are discussed.In addition,some new technologies of supercritical CO2 fracturing are introduced.The challenges and prospects in the current research are also summarized.For example,supercritical CO2 is prone to filtration when passing through porous media,and it is difficult to form a stable flow state.Therefore,in order to achieve stable fracturing fluid suspension and effectively support fractu res,it is urge nt to explo re new fracturing fluid additives or improve fracturing fluid formulations combined with the research of new proppants.This paper is of great significance for understanding the behavior mechanism of supercritical CO2 in shale and optimizing fracturing technology.展开更多
The utilization of ironsand for preparing oxidized pellets poses challenges,including slow oxidation and low consolidation strength.The effects and function mechanisms of high-pressure grinding roll(HPGR)pretreatment ...The utilization of ironsand for preparing oxidized pellets poses challenges,including slow oxidation and low consolidation strength.The effects and function mechanisms of high-pressure grinding roll(HPGR)pretreatment on the oxidation and consolidation of ironsand pellets were investigated,and the energy utilization efficiency of HPGR with different roller pressure intensities was evaluated.The results indicate that HPGR pretreatment at 8 MPa improves the ironsand properties,with the specific surface area increasing by 740 cm2 g-1 and mechanical energy storage increasing by 2.5 kJ mol-1,which is conducive to oxidation and crystalline connection of particles.As roller pressure intensity increases to 16 MPa,more mechanical energy of HPGR is applied for crystal activation,with mechanical energy storage further rising by 18.1 kJ mol-1.The apparent activation energy for pellet oxidation initially decreases and then increases,reaching a minimum at 12 MPa.Simultaneously,the roasted pellets porosity decreases by 2.8%,while the compressive strength increases by 789 N.At higher roller pressure intensity,the densely connected structure between particles impedes gas diffusion within the pellets,diminishing the beneficial effects of HPGR on pellet oxidation.Moreover,excessive roller pressure intensity decreases the HPGR energy utilization efficiency.The optimal HPGR roller pressure intensity for ironsand is 12 MPa,at which the specific surface area increases by 790 cm2 g-1,mechanical energy storage increases by 10.6 kJ mol-1,the compressive strength of roasted pellets rises to 2816 N,and the appropriate preheating and roasting temperatures decrease by 250 and 125°C,respectively.展开更多
In the production of castings,intrusive gas pore represents a kind of common defects which can lead to leakage in high gas-tightness requirement castings,such as cylinder blocks and cylinder heads for engines.It occur...In the production of castings,intrusive gas pore represents a kind of common defects which can lead to leakage in high gas-tightness requirement castings,such as cylinder blocks and cylinder heads for engines.It occurs due to the intrusion of gases generated during the resin burning of the sand core into castings during the casting process.Therefore,a gas generation and flow constitution model was established,in which the gas generation rate is a function of temperature and time,and the flow of gas is controlled by the gas release,conservation,and Darcy's law.The heat transfer and gas flow during casting process was numerically simulated.The dangerous point of cores is firstly identified by a virtual heat transfer method based on the similarity between heat transfer and gas flow in the sand core.The gas pores in castings are predicted by the gas pressure,the viscosity and state of the melt for these dangerous points.Three distinct sand core structures were designed and used for the production of iron castings,and the simulated gas pore results were validated by the obtained castings.展开更多
The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSN...The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSNS-II)commenced in 2024.The CSNS-II linac design primarily involves the addition of a radio-frequency ion source and a section of a superconducting linear accelerator composed of two types of superconducting cavities,namely double-spoke and six-cell elliptical cavities,after the drift tube linac(DTL).The development of the double-spoke superconducting cavity began in early 2021,and by January 2023,the welding,post-processing,and vertical tests of two 324 MHz double-spoke cavity prototypes were completed,with vertical test gradients of 11.6 and 15 MV/m,and Q0≥3×1010@Eacc≤10 MV/m.The R&D of the cryomodule began in January 2022.In October 2023,the clean assembly of the double-spoke cavity string and cold mass installation of the cryomodule commenced,with the installation of the cryomodule and valve box completing in two months.In January 2024,a horizontal test of the cryomodule was completed,making it the first double-spoke cavity cryomodule in China.The test results showed that the maximum gradients of the two superconducting cavities at a pulse width of 4 ms and repetition frequency of 25 Hz were 12.8 and 15.2 MV/m,respectively.This article provides a detailed introduction to the double-spoke superconducting cavity,tuner,coupler,and cryomodule,elaborates on the clean assembly of the cavity string and cold mass installation of the cryomodule,and provides a detailed analysis of the horizontal test results.展开更多
Sodium-sulfur(Na-S)batteries are considered as a promising successor to the next-generation of high-capacity,low-cost and environmentally friendly sulfur-based battery systems.However,Na-S batteries still suffer from ...Sodium-sulfur(Na-S)batteries are considered as a promising successor to the next-generation of high-capacity,low-cost and environmentally friendly sulfur-based battery systems.However,Na-S batteries still suffer from the“shuttle effect”and sluggish ion transport kinetics due to the dissolution of sodium polysulfides and poor conductivity of sulfur.MXenes,as 2D transition metal carbidesitrides,have exhibited excellent conductivity,diverse structure and tunable surface groups,particularly playing a crucial role in inhibiting polysulfide shuttle and sodium dendrite growth.In this review,achievements and advancements of MXene-based Na-S batteries are discussed,including applications of a sulfur cathode,separator,interlayer between separator and cathode,and sodium anode.In the end,perspectives and challenges on the future development of MXene-based materials in Na-S batteries are proposed.展开更多
To fulfill the training requirements for the daily operations of multirotor unmanned aerial vehicles(UAVs)clusters,a UAV cluster collaborative task integrated simulation platform(UAV-TISP)was developed.The platform in...To fulfill the training requirements for the daily operations of multirotor unmanned aerial vehicles(UAVs)clusters,a UAV cluster collaborative task integrated simulation platform(UAV-TISP)was developed.The platform integrates a suite of hardware and software to simulate a range of collaborative UAV cluster operation scenarios.It features modules for collaborative task planning,UAV cluster simulations,and tactical monitoring.The platform significantly reduces training costs by eliminating physical drone dependencies while offering a flexible environment for testing swarm algorithms.UAV-TISP supports both individual UAV and swarm operations,incorporating high-fidelity flight dynamics,real-time communication via user datagram protocol(UDP),and collision avoidance strategies.Utilizing the OSGEarth engine,it enables dynamic 3D environment visualization and scenario customization.Three key task scenarios-route flight,formation reconstruction,and formation transformation-were tested to validate the platform’s efficacy.Results demonstrated robust formation maintenance,adaptive collision avoidance,and seamless task execution.Comparative analysis with Gazebo Sim revealed lower trajectory deviations in UAV-TISP,highlighting its superior accuracy in simulating real-world flight dynamics.Future work will focus on enhancing scalability for diverse UAV models,optimizing swarm networking under communication constraints,and expanding mission scenarios.UAV-TISP serves as a versatile tool for both operational training and advanced algorithm development in UAV cluster applications.展开更多
The implementation of embedded selective catalytic reduction(SCR)denitration in chain grate during iron ore pelletizing process obviates additional flue gas heating.However,the influence of gas components and alkali m...The implementation of embedded selective catalytic reduction(SCR)denitration in chain grate during iron ore pelletizing process obviates additional flue gas heating.However,the influence of gas components and alkali metal on SCR denitration requires attention.The SCR denitration behavior in the preheating section of chain grate was investigated,and the combined influence mechanisms of H2O(g),SO2,and potassium were revealed.The results show that the presence of H2O(g)and SO2 in the flue gas decreases the NO conversion rate of the catalyst from 96.3%to 79.5%,while potassium adsorbed on the catalyst surface further reduces the NO conversion rate to 74.1%.H2O(g),SO2,and potassium in the flue gas form sulfate and potassium salt on the catalyst surface,blocking the pore structure,thereby decreasing the gas adsorption capacity of the catalyst.Moreover,SO2 and potassium engage in competitive adsorption and reaction with NH3 and NO at the active sites on the catalyst surface,reducing the content and activity of the catalyst effective component.Increasing the flue gas temperature can promote the decomposition of ammonium sulfate and ammonium bisulfate on the catalyst surface,but it has little effect on potassium.Additionally,potassium will exacerbate sulfur poisoning of the catalyst.Hence,the embedded SCR denitration process requires electrostatic precipitation to eliminate the adverse impacts of potassium and thermal regime optimization to raise flue gas temperature to 350℃,thereby increasing NO conversion rate exceeding 85%.展开更多
In high-frequency electrical energy systems,polyimide(PI)composite insulation materials need to possess a low dielectric constant,sufficient thermal conductivity,and robust interfacial adhesion to ensure reliable perf...In high-frequency electrical energy systems,polyimide(PI)composite insulation materials need to possess a low dielectric constant,sufficient thermal conductivity,and robust interfacial adhesion to ensure reliable performance under elevated temperatures and pressures.These aspects are crucial for preventing local overheating and electrical breakdown,thereby ensuring reliable equipment operation.Traditional PI insulation materials often exhibit high dielectric constants and pronounced dielectric losses,compromising their insulation efficiency.In this study,molecular dynamics simulations were employed to incorporate polyhedral oligomeric silsesquioxanes(POSS)into PI through physical blending and chemical bonding to enhance dielectric properties.Key parameters of the PI/POSS composite system,including dielectric constant,thermal conductivity,glass transition temperature,Young’s modulus,Poisson’s ratio,and interfacial adhesion energy,were systematically evaluated for both doping methods.The degradation behavior of the PI composites under high-temperature and electric field conditions was also simulated to elucidate degradation pathways and product distributions,providing insights for designing low-dielectric insulation materials.Doping with POSS significantly reduces the dielectric constant of PI,thereby improving insulation performance,thermal stability,mechanical strength,and interfacial adhesion.At an optimal POSS doping ratio,the thermal conductivity of PI is enhanced.Compared with the physical blending system,the chemical bonding system yields more substantial improvements across all evaluated properties.Under high-temperature and strong electric field conditions,POSS doping enhances interfacial adhesion and thermal stability,effectively suppressing the cleavage of key chemical bonds,reducingCOemissions,and increasing the formation of oxygen-containing intermediates and water molecules,which contributes to improved environmental sustainability.展开更多
Controlling the adhesion of potentially corrosive substances from flue gas on grate bar is crucial for extending the operational lifespan of the equipment.The adhesive behaviour and mechanism of ultrafine particulate ...Controlling the adhesion of potentially corrosive substances from flue gas on grate bar is crucial for extending the operational lifespan of the equipment.The adhesive behaviour and mechanism of ultrafine particulate matters(UPM)throughout the sintering process were elucidated,and measures to control adhesion on grate bars were developed.Research findings indicated that a small quantity of UPM were found on grate bar during the initial sintering stages(ignition stage and middle stageⅠandⅡ).The main compositions of UPM were FexOy-rich,CaO-rich,and aluminium silicate-rich particles.In contrast,corrosive substances like alkali metal compounds were almost absent.These UPM adhered onto grate bar primarily through inertial impaction.When moving to the final sintering stages(middle stageⅢand temperature rising stage),many UPM rich in corrosive substances like NaCl and KCl adhered to the grate bar.These UPM adhered to grate bar through thermal diffusion and vortex deposition.Solid waste water washing technology can greatly decrease the quantity of UPM(rich in NaCl and KCl)on the grate bar due to vortex deposition and thermal diffusion,and it represents a potentially promising way to control adhesion and corrosion on grate bars.展开更多
BACKGROUND Atrial fibrillation(AF)is a common cardiac arrhythmia in the elderly.This study aimed to evaluate urban-rural disparities in its prevalence and management in elderly Chinese.METHODS Consecutive participants...BACKGROUND Atrial fibrillation(AF)is a common cardiac arrhythmia in the elderly.This study aimed to evaluate urban-rural disparities in its prevalence and management in elderly Chinese.METHODS Consecutive participants aged≥65 years attending outpatient clinics were enrolled for AF screening using handheld single-lead electrocardiogram(ECG)from April 2017 to December 2022.Each ECG rhythm strip was reviewed from the research team.AF or uninterpretable single-lead ECGs were referred for 12-lead ECG.Primary study outcome comparison was between rural and urban areas for the prevalence of AF.The Student’s t-test was used to compare mean values of clinical characteristics between rural and urban participants,while the Pearson’s chi-square test was used to compare between-group proportions.Multivariate stepwise logistic regression analysis was performed to estimate the association between AF and various patient characteristics.RESULTS The 29,166 study participants included 13,253 men(45.4%)and had a mean age of 72.2 years.The 7073 rural participants differed significantly(P≤0.02)from the 22,093 urban participants in several major characteristics,such as older age,greater body mass index,and so on.The overall prevalence of AF was 4.6%(n=1347).AF was more prevalent in 7073 rural participants than 22,093 urban participants(5.6%vs.4.3%,P<0.01),before and after adjustment for age,body mass index,blood pressure,pulse rate,cigarette smoking,alcohol consumption and prior medical history.Multivariate logistic regression analysis identified overweight/obesity(OR=1.35,95%CI:1.17–1.54)in urban areas and cigarette smoking(OR=1.62,95%CI:1.20–2.17)and alcohol consumption(OR=1.42,95%CI:1.04–1.93)in rural areas as specific risk factors for prevalent AF.In patients with known AF in urban areas(n=781)and rural areas(n=338),60.6%and 45.9%,respectively,received AF treatment(P<0.01),and only 22.4%and 17.2%,respectively,received anticoagulation therapy(P=0.05).CONCLUSIONS In China,there are urban-rural disparities in AF in the elderly,with a higher prevalence and worse management in rural areas than urban areas.Our study findings provide insight for health policymakers to consider urban-rural disparity in the prevention and treatment of AF.展开更多
BACKGROUND Hem-o-lock clip,a versatile and reliable non-absorbable tissue clip,has gained widespread acceptance in laparoscopic surgeries for vessel ligation and tissue approximation.Its efficacy and safety have been ...BACKGROUND Hem-o-lock clip,a versatile and reliable non-absorbable tissue clip,has gained widespread acceptance in laparoscopic surgeries for vessel ligation and tissue approximation.Its efficacy and safety have been well-documented.CASE SUMMARY This case report describes the occurrence of a bronchopleural fistula following the application of the Hem-o-lock clip for the treatment of a lobar bronchial stump after lobectomy.CONCLUSION This case underscores the importance of exercising caution when using the Hem-o-lock clip for the management of non-vascular tissues during thoracic surgery.展开更多
In the present study,the effects of process parameters(output voltage x,nitrogen flux l and specific strengthening time s)on the microstructure and wear resistance properties of TiN coatings prepared by electrospark d...In the present study,the effects of process parameters(output voltage x,nitrogen flux l and specific strengthening time s)on the microstructure and wear resistance properties of TiN coatings prepared by electrospark deposition(ESD)were investigatedsystematically.The microstructure of the coatings was characterized for thickness(TOC),content of TiN(CON)and porosity(POC).A statistical model was developed to identify the significant factors affecting the microstructure and wear resistance of the coatings.The results show that the output voltage x and nitrogen flux l present significant effects on majority of the evaluation indexes such asTOC,friction coefficient(COF)and wear mass loss(Id),while the specific strengthening time s has a significant effect on POC and asmall effect on the other indexes.The optimal process parameters were obtained as follows:output voltage(x,60V),nitrogen flux(l,15L/min)and specific strengthening time(s,3min/cm2).The variation of wear mass loss(Id)by the variation of the outputvoltage(x)and nitrogen flux(l)is attributed to the change of wear mechanisms of TiN coatings.The main wear mechanism of TiNcoating prepared under optimal process parameters is micro-cutting wear accompanied by micro-fracture wear.展开更多
Gallium oxide(Ga_2O_3), a typical ultra wide bandgap semiconductor, with a bandgap of ~4.9 e V, critical breakdown field of 8 MV/cm, and Baliga's figure of merit of 3444, is promising to be used in high-power and ...Gallium oxide(Ga_2O_3), a typical ultra wide bandgap semiconductor, with a bandgap of ~4.9 e V, critical breakdown field of 8 MV/cm, and Baliga's figure of merit of 3444, is promising to be used in high-power and high-voltage devices.Recently, a keen interest in employing Ga_2O_3 in power devices has been aroused. Many researches have verified that Ga_2O_3 is an ideal candidate for fabricating power devices. In this review, we summarized the recent progress of field-effect transistors(FETs) and Schottky barrier diodes(SBDs) based on Ga_2O_3, which may provide a guideline for Ga_2O_3 to be preferably used in power devices fabrication.展开更多
We aimed to establish a novel rat model of seminal vesiculitis that would provide an effective approach to investigate the pathogenesis of this disease in the future. Eight male rats received the same operation, durin...We aimed to establish a novel rat model of seminal vesiculitis that would provide an effective approach to investigate the pathogenesis of this disease in the future. Eight male rats received the same operation, during which the root of one of the two seminal vesicles was partly ligatured with sutures and the other vesicle was left in tact. The samples of seminal vesicles were harvested on the 8th day followi ng the operation. Hematoxylin and eosi n and Mass on's trichrome stains were used to observe the histopathology and the presenee of fibrous tissue in seminal vesicles, respectively. Immunoblotting and immunohistochemistry were applied to determine the tumor n ecrosis factor-alpha and cyclooxygenase-2 levels in semi nal vesicle tissues. Real-time fluoresce nee qua ntitative polymerase chain reaction was performed to measure the gene expression levels of proinflammatory cytokines. H2O2 levels in the seminal plasma from the seminal vesicle were also measured. Hematoxylin and eosin staining suggested that there was inflammatory cell in filtration into the semi nal vesicles treated by partial root ligati on. The tumor n ecrosis factor-alpha and cyclooxygenase-2 proteins were significantly upregulated in the treated seminal vesicles. The tumor necrosis factor-alpha, cyclooxygenase, interleukin 6, and inducible nitric oxide synthase mRNA expression levels were also upregulated in the treated seminal vesicles. The H2O2 levels in the seminal plasma from seminal vesicles with partial root ligation were significantly elevated compared with those from vesicle left intact. In conclusion, partially ligating the root of the seminal vesicle via sutures in rats is an effective method to establish a seminal vesiculitis rat model.展开更多
基金the support received from the National Natural Science Foundation of China(No.52202213)the Shandong Province Youth Fund(Nos.ZR2024QE439,ZR2024QE532)+2 种基金the Scientific Research Fund of Dezhou University(No.30103540)the China Postdoctoral Science Foundation(No.2023M730905)the Science Research Project of the Hebei Education Department(No.QN2024031)。
摘要A cost-effective Fe-P-C nanocrystalline alloy(Fe85P_9C_6)was developed via melt-spinning by eliminating expensive alloying elements and post-annealing steps.The microstructure consists of an amorphous matrix with uniformly dispersed nanocrystalline clusters,featuring an average size of approximately 5 nm.This dual-phase structure remains thermally stable up to 569 K and results in excellent magnetic and mechanical performance,including a high saturation magnetic induction of 1.69 T,Vickers hardness of 621 HV,and outstanding bending ductility.Crystallization proceeds via the transformation of a metastable fcc-(Fe,P,C)phase intoα-Fe,Fe3C,and Fe3P,driven by internal stress arising from atomic size mismatch.Continuous heating and cooling transformation diagrams further reveal that this process can be precisely controlled to optimize phase evolution.The high Fe content and stress-relaxed nanocrystalline clusters contribute to enhanced in-plane magnetic anisotropy and rapid domain response.This simplified,annealing-free approach not only reduces material and processing costs but also provides a viable pathway for scalable fabrication of next-generation soft magnetic alloys with superior performance and manufacturability.
基金supported by the National Key Research and Development Program of China(2023YFC3707001)the National Natural Science Foundation of China(No.52274344)+1 种基金the Provincial Natural Science Foundation of Hunan(No.2023JJ20068)the Science and Technology Program of Hunan Province(2023RC3042).
摘要Low-temperature reduction degradation(LTRD)has long been regarded as a key metallurgical property of iron ore sinter,which exhibits a significant influence on the stability and efficiency of blast furnace operation.However,the reduction behavior of sinter under low-temperature conditions is not yet fully understood.The low-temperature reduction behavior of sinter was investigated.The reduction mechanism of sinter under low-temperature conditions was clarified through characterization methods,including X-ray diffraction,microstructural analysis and energy-dispersive X-ray spectroscopy.An interesting phenomenon was found that the reduction degradation index RDI+3.15 of sinter sharply decreased from 86.05%after reducing for 30 min and to 58.6%for 45 min.The reduction behavior of sinter was further investigated using a thermogravimetric furnace.The results showed that the reduction rate initially reached a peak,followed by a sharp decline to a minimum at approximately 10 min.This decrease occurred as a result of the formation of a reaction product layer,which hindered the diffusion of the reducing gas into the interior of the sinter.Subsequently,the reduction rate increased again,reaching a second peak at approximately 40 min.The increase in reduction rate was attributed to the formation of cracks rather than gas diffusion.It was further determined that the primary cause of LTRD is the volumetric expansion induced by the reduction of surface hematite.Moreover,the low-temperature reduction of sinter involved only the transformation of hematite to magnetite,with the overall reduction degree remaining low at only 6.31%.
基金supported by the National Key Research and Development Programs of China(2023YFD1801301,2022YFC2603801)National Natural Science Foundation of China(82341106)。
摘要Comprehensive characterization of mammalian gut viromes is essential for early detection of commensal and potentially zoonotic viruses and for reducing the risk of cross-species transmission.Viral metagenomics was applied to profile gut viral communities from zoo mammals maintained across multiple zoological institutions in China.Viral communities differed markedly among host dietary guilds,with herbivores exhibiting the highest viral species diversity.In total,1027 viral sequences representing five major viral groups were recovered,including multiple mammal-associated astroviruses,picornaviruses,and parvoviruses with potential infectivity.Phylogenetic reconstruction based on viral hallmark genes demonstrated extensive genomic diversification across recovered lineages.Hosts for most microviruses were predicted to belong to the bacterial family Bacteroidaceae.In addition,10 previously unreported crAss-like phages were identified in mammalian samples and showed close evolutionary relationships with proposed crAssphages from the human gut virome.Antibiotic resistance genes identified in the mammalian gut viromes primarily belonged to tetracyclines.These findings substantially expand current understanding of viral community structure in captive animals in China and provide a foundation for proactive surveillance frameworks targeting emerging mammalian viruses with zoonotic potential.
基金supported by the Science and Technology Innovation and Demonstration Project of the Department of Transport of Yunnan Province(Project No.2023-166).
摘要Tunnel micro-deformation is a progressive mechanical response process of geotechnical media under the influence of stress redistribution,environmental loads,material aging and other factors.Its millimeterlevel dynamic evolution is difcult to eectively capture by traditional monitoring technologies.Based on the physical mechanism of microwave remote sensing,this paper uses Ground-Based Synthetic Aperture Radar(GB-SAR)for continuous,non-contact deformation perception of tunnel structures.The system transmits and receives coherent electromagnetic wave signals,and extracts millimeter-level even sub-millimeter-level deformation information by means of dierential interferometry technology.Combined with typical tunnel engineering cases,the study verifies the monitoring stability and reliability of the system under different geological conditions and complex environments.The results show that the system can realize real-time,highprecision monitoring of the full-section deformation eld of tunnels with high early warning accuracy and strong environmental adaptability,providing an effective geophysical technical means for tunnel structure health diagnosis and safe operation and maintenance.
基金Supported by Science and Technology Development Project of the Affiliated Hospital of Weifang Medical University Funds,No.2023FYM015Tianjin Key Medical Discipline(Specialty)Construction Project,No.TJYXZDXK-3-002C.
摘要BACKGROUND Circulating irisin,a myokine,has been inconsistently associated with prediabetes mellitus(PreDM),and its relationship with glucagon is unexplored.Methodological variability,particularly between different enzyme-linked immunosorbent assay(ELISA)kits,is hypothesized to be a primary source of these discrepancies.Therefore,we hypothesized that the reported irisin-PreDM association is critically confounded by assay methodology and inadequate adjustment for key metabolic factors.AIM To investigate circulating irisin in PreDM via a dual-study approach,evaluating methodological variability and metabolic confounders.METHODS A dual-study design was employed:(1)A systematic review and meta-analysis of observational studies;and(2)A single-center,exploratory case-control study of 35 participants(9 PreDM,26 controls)from a tertiary hospital.Irisin was measured with two commercial ELISA kits(ELK and Elabscience).Key analyses included random-effects meta-analysis,multiple linear regression,Spearman correlation,and Bland-Altman analysis for inter-assay agreement.RESULTS The meta-analysis(8 studies,n=788)found significantly lower irisin in PreDM(standardized mean difference=-0.524,95%confidence interval:-0.897 to-0.152,P=0.006)with high heterogeneity(I2=86.7%).In the case-control study,unadjusted analysis showed higher irisin in PreDM with the Elabscience kit(median:7386.3 pg/mL vs 6332.0 pg/mL,P=0.045)but not the ELK kit.After adjusting for gender,body mass index,and fatty liver,the association was null for both kits.Bland-Altman analysis revealed poor inter-assay agreement(mean bias:5837.25 pg/mL).Irisin correlated with fatty liver(ρ=0.350,P=0.039)and 0.5-hour glucose(ρ=0.421,P=0.012),but not with glucagon.CONCLUSION The irisin-PreDM relationship appears to be influenced by assay methodology and metabolic factors.Standardizing irisin measurement and adjusting for key confounders are important considerations for future research.
基金Supported by the Clinical Research and Translational Promotion Project of China-Japan Friendship Hospital,No.2022-NHLHCRF-LX-02.
摘要BACKGROUND Anal fistula is a common anorectal disorder for which conventional surgical procedures often result in relatively high recurrence and complication rates.Ligation of the intersphincteric fistula tract(LIFT),a sphincter-preserving technique,has emerged as a potential alternative.AIM To systematically evaluate and compare the clinical efficacy,safety,and postoperative outcomes of LIFT vs conventional surgical approaches in the management of anal fistula using evidence from randomized controlled trials(RCTs).METHODS In accordance with Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines,we conducted a comprehensive systematic search of both Chinese and international databases to identify RCTs published during January 2014 to 2025.Studies were deemed eligible if they directly compared LIFT with conventional surgical approaches,such as seton placement,fistulotomy,and fistulectomy.The extracted data were analyzed using Review Manager;the methodological quality of the included trials was rigorously evaluated by using the Cochrane risk-of-bias tool.RESULTS In total,107 RCTs involving 9401 participants met the inclusion criteria.LIFT yielded higher healing rates and significantly lower recurrence and complication rates than conventional surgery.Patients undergoing LIFT reported a lower postoperative pain,shorter woundhealing duration,and better preservation of the anal sphincter function.No significant difference was recorded in the operative time between the two groups.CONCLUSION The LIFT procedure demonstrated clear advantages over conventional surgical methods in terms of clinical efficacy,safety,and postoperative recovery,supporting the former’s role as an effective and sphincter-preserving treatment for anal fistula.Nevertheless,most available trials are limited by short follow-up durations and heterogeneous outcome definitions,underscoring the need for undertaking large,multicenter RCTs employing standardized endpoints.
摘要With the increasing demand for energy,traditional oil resources are facing depletion and insufficient supply.Many countries are rapidly turning to the development of unconventional oil and gas resources.Among them,shale oil and gas reservoirs have become the focus of unconventional oil and gas resources exploration and development.Based on the characteristics of shale oil and gas reservoirs,supercritical CO2 fracturing is more conducive to improving oil recovery than other fracturing technologies.In this paper,the mechanism of fracture initiation and propagation of supercritical CO2 in shale is analyzed,including viscosity effect,surface tension effect,permeation diffusion effect of supercritical CO2,and dissolution-adsorption effect between CO2 and shale.The effects of natural factors,such as shale properties,bedding plane and natural fractures,and controllable factors,proppant,temperature,pressure,CO2 concentration and injection rate on fracture initiation and propagation are clarified.The methods of supercritical CO2 fracturing process,thickener and proppant optimization to improve the efficiency of supercritical CO2 fracturing are discussed.In addition,some new technologies of supercritical CO2 fracturing are introduced.The challenges and prospects in the current research are also summarized.For example,supercritical CO2 is prone to filtration when passing through porous media,and it is difficult to form a stable flow state.Therefore,in order to achieve stable fracturing fluid suspension and effectively support fractu res,it is urge nt to explo re new fracturing fluid additives or improve fracturing fluid formulations combined with the research of new proppants.This paper is of great significance for understanding the behavior mechanism of supercritical CO2 in shale and optimizing fracturing technology.
基金financially supported by the General Program of National Natural Science Foundation of China(No.52174330)Hunan Provincial Innovation Foundation for Postgraduate(No.QL20220069)Postgraduate Innovative Project of Central South University(No.1053320214756).
摘要The utilization of ironsand for preparing oxidized pellets poses challenges,including slow oxidation and low consolidation strength.The effects and function mechanisms of high-pressure grinding roll(HPGR)pretreatment on the oxidation and consolidation of ironsand pellets were investigated,and the energy utilization efficiency of HPGR with different roller pressure intensities was evaluated.The results indicate that HPGR pretreatment at 8 MPa improves the ironsand properties,with the specific surface area increasing by 740 cm2 g-1 and mechanical energy storage increasing by 2.5 kJ mol-1,which is conducive to oxidation and crystalline connection of particles.As roller pressure intensity increases to 16 MPa,more mechanical energy of HPGR is applied for crystal activation,with mechanical energy storage further rising by 18.1 kJ mol-1.The apparent activation energy for pellet oxidation initially decreases and then increases,reaching a minimum at 12 MPa.Simultaneously,the roasted pellets porosity decreases by 2.8%,while the compressive strength increases by 789 N.At higher roller pressure intensity,the densely connected structure between particles impedes gas diffusion within the pellets,diminishing the beneficial effects of HPGR on pellet oxidation.Moreover,excessive roller pressure intensity decreases the HPGR energy utilization efficiency.The optimal HPGR roller pressure intensity for ironsand is 12 MPa,at which the specific surface area increases by 790 cm2 g-1,mechanical energy storage increases by 10.6 kJ mol-1,the compressive strength of roasted pellets rises to 2816 N,and the appropriate preheating and roasting temperatures decrease by 250 and 125°C,respectively.
基金funded by the Beijing Nature Sciences Fund Haidian Originality Cooperation Project (Grant No. L212002)。
摘要In the production of castings,intrusive gas pore represents a kind of common defects which can lead to leakage in high gas-tightness requirement castings,such as cylinder blocks and cylinder heads for engines.It occurs due to the intrusion of gases generated during the resin burning of the sand core into castings during the casting process.Therefore,a gas generation and flow constitution model was established,in which the gas generation rate is a function of temperature and time,and the flow of gas is controlled by the gas release,conservation,and Darcy's law.The heat transfer and gas flow during casting process was numerically simulated.The dangerous point of cores is firstly identified by a virtual heat transfer method based on the similarity between heat transfer and gas flow in the sand core.The gas pores in castings are predicted by the gas pressure,the viscosity and state of the melt for these dangerous points.Three distinct sand core structures were designed and used for the production of iron castings,and the simulated gas pore results were validated by the obtained castings.
摘要The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSNS-II)commenced in 2024.The CSNS-II linac design primarily involves the addition of a radio-frequency ion source and a section of a superconducting linear accelerator composed of two types of superconducting cavities,namely double-spoke and six-cell elliptical cavities,after the drift tube linac(DTL).The development of the double-spoke superconducting cavity began in early 2021,and by January 2023,the welding,post-processing,and vertical tests of two 324 MHz double-spoke cavity prototypes were completed,with vertical test gradients of 11.6 and 15 MV/m,and Q0≥3×1010@Eacc≤10 MV/m.The R&D of the cryomodule began in January 2022.In October 2023,the clean assembly of the double-spoke cavity string and cold mass installation of the cryomodule commenced,with the installation of the cryomodule and valve box completing in two months.In January 2024,a horizontal test of the cryomodule was completed,making it the first double-spoke cavity cryomodule in China.The test results showed that the maximum gradients of the two superconducting cavities at a pulse width of 4 ms and repetition frequency of 25 Hz were 12.8 and 15.2 MV/m,respectively.This article provides a detailed introduction to the double-spoke superconducting cavity,tuner,coupler,and cryomodule,elaborates on the clean assembly of the cavity string and cold mass installation of the cryomodule,and provides a detailed analysis of the horizontal test results.
基金supported by the National Natural Science Foundation of China(Nos.51972198 and 61633015)the Natural Science Foundation of Shandong Province(No.ZR2020JQ19)+1 种基金Taishan Scholars Program of Shandong Province(No.ts20190908)Shenzhen Fundamental Research Program(No.JCYJ20190807093405503).
摘要Sodium-sulfur(Na-S)batteries are considered as a promising successor to the next-generation of high-capacity,low-cost and environmentally friendly sulfur-based battery systems.However,Na-S batteries still suffer from the“shuttle effect”and sluggish ion transport kinetics due to the dissolution of sodium polysulfides and poor conductivity of sulfur.MXenes,as 2D transition metal carbidesitrides,have exhibited excellent conductivity,diverse structure and tunable surface groups,particularly playing a crucial role in inhibiting polysulfide shuttle and sodium dendrite growth.In this review,achievements and advancements of MXene-based Na-S batteries are discussed,including applications of a sulfur cathode,separator,interlayer between separator and cathode,and sodium anode.In the end,perspectives and challenges on the future development of MXene-based materials in Na-S batteries are proposed.
摘要To fulfill the training requirements for the daily operations of multirotor unmanned aerial vehicles(UAVs)clusters,a UAV cluster collaborative task integrated simulation platform(UAV-TISP)was developed.The platform integrates a suite of hardware and software to simulate a range of collaborative UAV cluster operation scenarios.It features modules for collaborative task planning,UAV cluster simulations,and tactical monitoring.The platform significantly reduces training costs by eliminating physical drone dependencies while offering a flexible environment for testing swarm algorithms.UAV-TISP supports both individual UAV and swarm operations,incorporating high-fidelity flight dynamics,real-time communication via user datagram protocol(UDP),and collision avoidance strategies.Utilizing the OSGEarth engine,it enables dynamic 3D environment visualization and scenario customization.Three key task scenarios-route flight,formation reconstruction,and formation transformation-were tested to validate the platform’s efficacy.Results demonstrated robust formation maintenance,adaptive collision avoidance,and seamless task execution.Comparative analysis with Gazebo Sim revealed lower trajectory deviations in UAV-TISP,highlighting its superior accuracy in simulating real-world flight dynamics.Future work will focus on enhancing scalability for diverse UAV models,optimizing swarm networking under communication constraints,and expanding mission scenarios.UAV-TISP serves as a versatile tool for both operational training and advanced algorithm development in UAV cluster applications.
基金financially supported by the National Key Research and Development Program of China(No.2023YFC3707002)Hunan Provincial Innovation Foundation for Postgraduate(No.QL20220069)Postgraduate Innovative Project of Central South University(No.1053320214756).
摘要The implementation of embedded selective catalytic reduction(SCR)denitration in chain grate during iron ore pelletizing process obviates additional flue gas heating.However,the influence of gas components and alkali metal on SCR denitration requires attention.The SCR denitration behavior in the preheating section of chain grate was investigated,and the combined influence mechanisms of H2O(g),SO2,and potassium were revealed.The results show that the presence of H2O(g)and SO2 in the flue gas decreases the NO conversion rate of the catalyst from 96.3%to 79.5%,while potassium adsorbed on the catalyst surface further reduces the NO conversion rate to 74.1%.H2O(g),SO2,and potassium in the flue gas form sulfate and potassium salt on the catalyst surface,blocking the pore structure,thereby decreasing the gas adsorption capacity of the catalyst.Moreover,SO2 and potassium engage in competitive adsorption and reaction with NH3 and NO at the active sites on the catalyst surface,reducing the content and activity of the catalyst effective component.Increasing the flue gas temperature can promote the decomposition of ammonium sulfate and ammonium bisulfate on the catalyst surface,but it has little effect on potassium.Additionally,potassium will exacerbate sulfur poisoning of the catalyst.Hence,the embedded SCR denitration process requires electrostatic precipitation to eliminate the adverse impacts of potassium and thermal regime optimization to raise flue gas temperature to 350℃,thereby increasing NO conversion rate exceeding 85%.
基金financially supported by the Natural Science Foundation of Shandong Province(No.ZR2021ME011)State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources(No.LAPS20001)。
摘要In high-frequency electrical energy systems,polyimide(PI)composite insulation materials need to possess a low dielectric constant,sufficient thermal conductivity,and robust interfacial adhesion to ensure reliable performance under elevated temperatures and pressures.These aspects are crucial for preventing local overheating and electrical breakdown,thereby ensuring reliable equipment operation.Traditional PI insulation materials often exhibit high dielectric constants and pronounced dielectric losses,compromising their insulation efficiency.In this study,molecular dynamics simulations were employed to incorporate polyhedral oligomeric silsesquioxanes(POSS)into PI through physical blending and chemical bonding to enhance dielectric properties.Key parameters of the PI/POSS composite system,including dielectric constant,thermal conductivity,glass transition temperature,Young’s modulus,Poisson’s ratio,and interfacial adhesion energy,were systematically evaluated for both doping methods.The degradation behavior of the PI composites under high-temperature and electric field conditions was also simulated to elucidate degradation pathways and product distributions,providing insights for designing low-dielectric insulation materials.Doping with POSS significantly reduces the dielectric constant of PI,thereby improving insulation performance,thermal stability,mechanical strength,and interfacial adhesion.At an optimal POSS doping ratio,the thermal conductivity of PI is enhanced.Compared with the physical blending system,the chemical bonding system yields more substantial improvements across all evaluated properties.Under high-temperature and strong electric field conditions,POSS doping enhances interfacial adhesion and thermal stability,effectively suppressing the cleavage of key chemical bonds,reducingCOemissions,and increasing the formation of oxygen-containing intermediates and water molecules,which contributes to improved environmental sustainability.
基金supported by the National Natural Science Foundation of China(No.52274344)the Provincial Natural Science Foundation of Hunan(Nos.2022JJ30723 and 2023JJ20068)the Science and Technology Innovation Program of Hunan Province(2023RC3042).
摘要Controlling the adhesion of potentially corrosive substances from flue gas on grate bar is crucial for extending the operational lifespan of the equipment.The adhesive behaviour and mechanism of ultrafine particulate matters(UPM)throughout the sintering process were elucidated,and measures to control adhesion on grate bars were developed.Research findings indicated that a small quantity of UPM were found on grate bar during the initial sintering stages(ignition stage and middle stageⅠandⅡ).The main compositions of UPM were FexOy-rich,CaO-rich,and aluminium silicate-rich particles.In contrast,corrosive substances like alkali metal compounds were almost absent.These UPM adhered onto grate bar primarily through inertial impaction.When moving to the final sintering stages(middle stageⅢand temperature rising stage),many UPM rich in corrosive substances like NaCl and KCl adhered to the grate bar.These UPM adhered to grate bar through thermal diffusion and vortex deposition.Solid waste water washing technology can greatly decrease the quantity of UPM(rich in NaCl and KCl)on the grate bar due to vortex deposition and thermal diffusion,and it represents a potentially promising way to control adhesion and corrosion on grate bars.
基金supported by the National Natural Science Foundation of China(No.82070432&No.82070435&No.82270469&No.82370426)the Ministry of Science and Technology,Beijing,China(2018YFC1704902&2022YFC3601302)+2 种基金the Shanghai Commissions of Science and Technology and Health(a special grant for“leading academics”)(No.19DZ2340200)the Three-year Action Program of Shanghai Municipality for Strengthening the Construction of Public Health System Big Data and Artificial Intelligence Application,Shanghai,China(GWV-10.1-XK05)the Clinical Research Program,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine(2018CR010).
摘要BACKGROUND Atrial fibrillation(AF)is a common cardiac arrhythmia in the elderly.This study aimed to evaluate urban-rural disparities in its prevalence and management in elderly Chinese.METHODS Consecutive participants aged≥65 years attending outpatient clinics were enrolled for AF screening using handheld single-lead electrocardiogram(ECG)from April 2017 to December 2022.Each ECG rhythm strip was reviewed from the research team.AF or uninterpretable single-lead ECGs were referred for 12-lead ECG.Primary study outcome comparison was between rural and urban areas for the prevalence of AF.The Student’s t-test was used to compare mean values of clinical characteristics between rural and urban participants,while the Pearson’s chi-square test was used to compare between-group proportions.Multivariate stepwise logistic regression analysis was performed to estimate the association between AF and various patient characteristics.RESULTS The 29,166 study participants included 13,253 men(45.4%)and had a mean age of 72.2 years.The 7073 rural participants differed significantly(P≤0.02)from the 22,093 urban participants in several major characteristics,such as older age,greater body mass index,and so on.The overall prevalence of AF was 4.6%(n=1347).AF was more prevalent in 7073 rural participants than 22,093 urban participants(5.6%vs.4.3%,P<0.01),before and after adjustment for age,body mass index,blood pressure,pulse rate,cigarette smoking,alcohol consumption and prior medical history.Multivariate logistic regression analysis identified overweight/obesity(OR=1.35,95%CI:1.17–1.54)in urban areas and cigarette smoking(OR=1.62,95%CI:1.20–2.17)and alcohol consumption(OR=1.42,95%CI:1.04–1.93)in rural areas as specific risk factors for prevalent AF.In patients with known AF in urban areas(n=781)and rural areas(n=338),60.6%and 45.9%,respectively,received AF treatment(P<0.01),and only 22.4%and 17.2%,respectively,received anticoagulation therapy(P=0.05).CONCLUSIONS In China,there are urban-rural disparities in AF in the elderly,with a higher prevalence and worse management in rural areas than urban areas.Our study findings provide insight for health policymakers to consider urban-rural disparity in the prevention and treatment of AF.
摘要BACKGROUND Hem-o-lock clip,a versatile and reliable non-absorbable tissue clip,has gained widespread acceptance in laparoscopic surgeries for vessel ligation and tissue approximation.Its efficacy and safety have been well-documented.CASE SUMMARY This case report describes the occurrence of a bronchopleural fistula following the application of the Hem-o-lock clip for the treatment of a lobar bronchial stump after lobectomy.CONCLUSION This case underscores the importance of exercising caution when using the Hem-o-lock clip for the management of non-vascular tissues during thoracic surgery.
摘要In the present study,the effects of process parameters(output voltage x,nitrogen flux l and specific strengthening time s)on the microstructure and wear resistance properties of TiN coatings prepared by electrospark deposition(ESD)were investigatedsystematically.The microstructure of the coatings was characterized for thickness(TOC),content of TiN(CON)and porosity(POC).A statistical model was developed to identify the significant factors affecting the microstructure and wear resistance of the coatings.The results show that the output voltage x and nitrogen flux l present significant effects on majority of the evaluation indexes such asTOC,friction coefficient(COF)and wear mass loss(Id),while the specific strengthening time s has a significant effect on POC and asmall effect on the other indexes.The optimal process parameters were obtained as follows:output voltage(x,60V),nitrogen flux(l,15L/min)and specific strengthening time(s,3min/cm2).The variation of wear mass loss(Id)by the variation of the outputvoltage(x)and nitrogen flux(l)is attributed to the change of wear mechanisms of TiN coatings.The main wear mechanism of TiNcoating prepared under optimal process parameters is micro-cutting wear accompanied by micro-fracture wear.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61774019,51572033,and 51572241)the Beijing Municipal Commission of Science and Technology,China(Grant No.SX2018-04)
摘要Gallium oxide(Ga_2O_3), a typical ultra wide bandgap semiconductor, with a bandgap of ~4.9 e V, critical breakdown field of 8 MV/cm, and Baliga's figure of merit of 3444, is promising to be used in high-power and high-voltage devices.Recently, a keen interest in employing Ga_2O_3 in power devices has been aroused. Many researches have verified that Ga_2O_3 is an ideal candidate for fabricating power devices. In this review, we summarized the recent progress of field-effect transistors(FETs) and Schottky barrier diodes(SBDs) based on Ga_2O_3, which may provide a guideline for Ga_2O_3 to be preferably used in power devices fabrication.
摘要We aimed to establish a novel rat model of seminal vesiculitis that would provide an effective approach to investigate the pathogenesis of this disease in the future. Eight male rats received the same operation, during which the root of one of the two seminal vesicles was partly ligatured with sutures and the other vesicle was left in tact. The samples of seminal vesicles were harvested on the 8th day followi ng the operation. Hematoxylin and eosi n and Mass on's trichrome stains were used to observe the histopathology and the presenee of fibrous tissue in seminal vesicles, respectively. Immunoblotting and immunohistochemistry were applied to determine the tumor n ecrosis factor-alpha and cyclooxygenase-2 levels in semi nal vesicle tissues. Real-time fluoresce nee qua ntitative polymerase chain reaction was performed to measure the gene expression levels of proinflammatory cytokines. H2O2 levels in the seminal plasma from the seminal vesicle were also measured. Hematoxylin and eosin staining suggested that there was inflammatory cell in filtration into the semi nal vesicles treated by partial root ligati on. The tumor n ecrosis factor-alpha and cyclooxygenase-2 proteins were significantly upregulated in the treated seminal vesicles. The tumor necrosis factor-alpha, cyclooxygenase, interleukin 6, and inducible nitric oxide synthase mRNA expression levels were also upregulated in the treated seminal vesicles. The H2O2 levels in the seminal plasma from seminal vesicles with partial root ligation were significantly elevated compared with those from vesicle left intact. In conclusion, partially ligating the root of the seminal vesicle via sutures in rats is an effective method to establish a seminal vesiculitis rat model.