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Phosphogypsum and cadmium remediation agents:A synergy for mitigating Cd contamination and CH4 emissions in rice paddies 认领 引用
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作者 Wangbiao Lu Chengling Huang +9 位作者 Weijun Luo Qi Zhang Xu Huang Yongcheng Jin Chen Yao Xiaowen Li Guangneng Zeng Fang Yang Liang Tang Shi-Jie Wang 《Acta Geochimica》 EI CAS CSCD 2026年第2期230-241,共12页
Rice paddies,a major anthropogenic source of atmospheric methane(CH4),currently face significant cadmium(Cd)pollution.China has a substantial storage of phosphogypsum intended to enhance arable soil fertility.Howev... Rice paddies,a major anthropogenic source of atmospheric methane(CH4),currently face significant cadmium(Cd)pollution.China has a substantial storage of phosphogypsum intended to enhance arable soil fertility.However,little is known about the impact of phosphogypsum on synergic Cd pollution and CH4 emission in rice paddies.In this study,we conducted a pot experiment to assess the effects of phosphogypsum,combined with Cd remediation agents such as sulfhydryl-modified palygorskite(SMP),bacillus subtilis(BS),and selenium foliar fertilizer(SFF),on soil and rice Cd contents and CH4 emissions.We found that a large amount of phosphogypsum(2250 kg ha-1)can significantly reduce the bioavailable Cd content in soils.Combining remediation agents with phosphogypsum effectively reduced Cd levels in brown rice.Phosphogypsum can significantly reduce CH4 emissions from rice paddies,resulting in cumulative evasion rates of 255.54-633.63 kg hm-2.Our results demonstrate that phosphogypsum paired with Cd remediation agents effectively reduces Cd contamination in brown rice and CH4 emissions from rice paddies,providing insights into the synergistic management of heavy metal pollution and greenhouse gas emissions in agricultural environments. 展开更多
关键词 Cd·CH4flux Phosphogypsum Remediation agents Synergistic effect Rice paddy
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文化赋能现代工业体系的理论基础、现实挑战与实现路径 认领 引用 被引量：1
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作者 黄旭 叶俊 梁雅爽 《产业经济评论》 CSSCI 2026年第1期155-172,共18页
在全球产业变革与要素结构调整的背景下,文化资源正日益成为推动现代工业体系重构的关键变量。作为一种具有认知引导、制度塑型与价值共创功能的核心要素,文化具备系统性经济属性,在新质生产力发展中发挥着基础性作用。本文以资源基础... 在全球产业变革与要素结构调整的背景下,文化资源正日益成为推动现代工业体系重构的关键变量。作为一种具有认知引导、制度塑型与价值共创功能的核心要素,文化具备系统性经济属性,在新质生产力发展中发挥着基础性作用。本文以资源基础理论、制度性逻辑与生态系统理论为基础,构建“文化嵌入—机制扩展—系统跃迁”的理论分析框架,系统揭示文化赋能现代工业体系的作用机制与传导路径。在此框架下,本文归纳出产品美学型、组织范式型与生态协同型三类典型赋能路径,并揭示其由外在附着向系统整合演化的过程逻辑。通过区域与行业典型实践的剖析,进一步总结文化在工业体系中的赋能样态与结构转化机制。在应对结构性障碍的基础上,本文提出从要素识别、协同机制到生态治理的多维联动优化路径,并构建“初始试点—模式扩展—生态集成”的推进策略。本文旨在为文化资源系统性嵌入现代工业体系、推动产业价值结构优化与创新生态构建提供理论支撑与实践参考。 展开更多
关键词 文化赋能 现代工业体系 产业升级
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Multi-Modal Risk Profiling-Driven Power Grid Disaster Emergency Response Strategies and Dynamic Resource Synergy Optimization Model 认领 引用
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作者 Zi’an Zhong Kun Hua +2 位作者 Xu Huang Shiyu Chen Ruiqi Chen 《Journal of Electronic Research and Application》 2026年第1期245-254,共10页
To improve the efficiency of power grid emergency response after disasters,this study proposes a multi-modal risk profiling-driven power grid disaster emergency response strategy and dynamic resource synergy optimizat... To improve the efficiency of power grid emergency response after disasters,this study proposes a multi-modal risk profiling-driven power grid disaster emergency response strategy and dynamic resource synergy optimization model.A risk assessment model is constructed by integrating equipment health status,real-time failure rate,and power grid topology importance to generate equipment risk profiles for identifying key nodes.A two-stage optimization mechanism is then designed,the first stage achieves priority coverage of high-risk equipment and minimization of inspection costs through multi-objective path planning.The second stage adopts a mixed-integer programming model to coordinate personnel scheduling and material allocation under resource constraints.A rolling optimization framework is introduced to dynamically respond to sudden failures and resource changes,ensuring the adaptability of scheduling schemes.To verify the model’s effectiveness,three typical scenarios,”no sudden failures”,“equipment risk escalation”,and“personnel working hour constraints”,are simulated.Compared with traditional strategies,the model significantly improves the rationality and dynamic adaptability of resource scheduling,providing new ideas and engineering practice support for enhancing the resilience of smart grid disaster emergency response. 展开更多
关键词 Multi-modal risk profiling Power grid disaster emergency response Mixed-integer programming Path planning
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Rapidly polymerized multifunctional hydrogel sensor initiated by nanocellulose-stabilized MXene-coated liquid metal for advanced wearable applications 认领 引用 被引量：1
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作者 Xu Huang Carlos Jonay Jiménez +3 位作者 Maria Guix Cristina Madrid Xufré Yisimayili Tuersun Sheng Chu 《Rare Metals》 SCIE EI CAS CSCD 2025年第9期6402-6416,共15页
Hydrogel strain sensors represent an importan development for research into flexible electronics,being able to convert external stimuli into easily monitored electrical signals.However,finding simple and rapid prepara... Hydrogel strain sensors represent an importan development for research into flexible electronics,being able to convert external stimuli into easily monitored electrical signals.However,finding simple and rapid preparation methods,as well as ensuring compatibility between conductive fillers and the polymer matrix are stil the main challenges for conductive hydrogel applications In this work,we utilize MXene to coat liquid metal dro plets that have been broken by ultrasound while incorpo rating cellulose nanofibers to make them stably dispersed Electron paramagnetic resonance spectroscopy revealed that the obtained composite filler could catalyze the releas of additional hydroxyl radicals from ammonium persulfat to enable the rapid gelation of acrylic acid under ambien conditions.This unique property allows for the mold-based fabrication of hydrogels in various shapes,and we also explored the use of microfluidic devices for printing.Th conductive hydrogels showed good tensile properties small hysteresis loops,high self-healing efficiency(97%conductive recovery),and antimicrobial properties.When assembled into flexible sensors,the hydrogel can accu rately monitor body movements with stable repeatability The outstanding characteristics of the hydrogel not only offer a material basis for the development of novel flexibl sensors,but also have the potential for rapid,large-scale and customized preparation through fast gelation. 展开更多
关键词 MXene Liquid metal Fast gelation Self-healing Conductive hydrogel Wearable sensor
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Metal-organic framework Cu-BTC for overall water splitting: A density functional theory study 认领 引用 被引量：3
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作者 Xu Huang Kai-Yin Wu +2 位作者 Chao Su Lei Yang Bei-Bei Xiao 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第4期552-557,共6页
Metal-organic framework(MOF) has been widely applied in photocatalysis, which is significant for addressing energy crises and environmental issues. Based on density functional theory calculations,the performances of C... Metal-organic framework(MOF) has been widely applied in photocatalysis, which is significant for addressing energy crises and environmental issues. Based on density functional theory calculations,the performances of Cu-BTC, a copper-based MOF, and its derivatives Cu TM-BTC via the substitution of transition metal(TM) elements at the Cu site for photocatalytic overall water splitting(POWS) have been studied. POWS of Cu-BTC suffers from the sluggish hydrogen evolution reaction due to the large overpotential of 2.02 V and limited solar utilization due to a wide HOMO-LUMO gap of 4.11 e V. Via TM substitution, the HOMO-LUMO gap narrows but still satisfies the redox potentials when taken 3d-TM of Cr, Fe, Co or Ni, 4d-TM of Rh or Pd, or 5d-TM of Re or Pt into consideration, benefiting for the light absorption. Furthermore, Cr and Re could serve as active sites for hydrogen evolution with remarkably lowered overpotentials of 0.79 V and 0.28 V, respectively;similarly, oxygen evolution activities could be enhanced by Fe, Co and Rh because of their reduced overpotentials which are less than 0.5 V. Therefore,our findings pave guidance for designing Cu-BTC derivatives in overall water splitting. 展开更多
关键词 Metal-organic framework Density functional theory Cu-BTC Photocatalysis Overall water splitting
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UV-aging reduces the effects of biodegradable microplastics on soil sulfamethoxazole degradation and sul genes development 认领 引用 被引量：2
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作者 Xuecong Sun Shaohua Tian +2 位作者 Lelan You Xu Huang Jian-Qiang Su 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2025年第4期422-431,共10页
In recent years,the biodegradable plastics has extensively used in industry,agriculture,and daily life.Herein,the effects of two biodegradable microplastics(BMPs),poly(butyleneadipate-co-terephthalate)(PBAT)and polyhy... In recent years,the biodegradable plastics has extensively used in industry,agriculture,and daily life.Herein,the effects of two biodegradable microplastics(BMPs),poly(butyleneadipate-co-terephthalate)(PBAT)and polyhydroxyalkanoate(PHA),on soil sulfamethoxazole(SMX)degradation and sul genes development were comparatively studied based on the type,dosage,and state.The addition of virgin BMPs significantly increased soil DOC following a sequential order PBAT>PHA and high dose>low dose.Meanwhile virgin PBAT significantly reduced soil pH.In general,the addition of BMPs not only promoted soil SMX degradation but also increased the abundance of sul genes,with an exception that pH reduction in virgin PBAT inhibited the proliferation of sul genes.The driving effects of BMPs on soil microbial diversity following the same order as that on DOC.Specific bacteria stimulated by BMPs,such as Arthrobacter and two genera affiliated with phylum TM7,accounted for the accelerated degradation of SMX.Intriguingly,UV-aging hindered the release of DOC from BMPs and the reduction in pH,mitigated the stimulation of microbial communities,and ultimately reduced the promotion effect of BMPs on SMX degradation and sul genes proliferation.Our results suggest that more attention should be paid to the proliferation risk of ARGs in the environment affected by BMPs and UV-aging can be employed sometimes to reduce this risk. 展开更多
关键词 Biodegradable plastics UV-aging Antibiotics degradation Antibiotic resistance genes Microbial community
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基坑阳角新型斜桩支护结构设计与作用研究 认领 引用
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作者 周大兵 徐煌 +2 位作者 刘永武 汪东林 刘金龙 《山西建筑》 2026年第6期76-80,共5页
异型基坑工程中,基坑阳角两面临空,是基坑较薄弱的地方,且变形较大,对基坑阳角处支护结构的刚度提出了更高要求。研究提出了一种基坑阳角的斜桩支护结构,包括斜桩、连梁、锚索与钢筋混凝土板;斜桩位于基坑阳角的坑外对角线上,斜桩的数... 异型基坑工程中,基坑阳角两面临空,是基坑较薄弱的地方,且变形较大,对基坑阳角处支护结构的刚度提出了更高要求。研究提出了一种基坑阳角的斜桩支护结构,包括斜桩、连梁、锚索与钢筋混凝土板;斜桩位于基坑阳角的坑外对角线上,斜桩的数量不少于两根;连梁连接基坑阳角对角线及两侧围护桩的冠梁,垂直于基坑阳角对角线的连梁不少于两道;锚索作用于垂直于基坑阳角对角线的最外侧连梁上;钢筋混凝土板位于垂直于基坑阳角对角线的最外侧两道连梁之间。所提斜桩、连梁与基坑冠梁组成多个三角形稳定体系,斜桩的下端朝向基坑的内侧倾斜设置,整体刚度大;最外侧连梁设置一排预应力锚索,锚索把抵抗基坑变形的拉力传递至远离基坑阳角处的土体中,有效减小了基坑阳角处支护结构的变形,为加强基坑阳角支护体系的刚度提供了一种新思路。 展开更多
关键词 基坑 阳角 斜桩 支护结构
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细胞衰老在顺铂所致急性肾脏损伤与肾脏纤维化中的作用机制研究进展 认领 引用
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作者 梁彧欣 林兰彦 +4 位作者 周悦 王豫伟 孔繁兴 徐煌 李素华 《中国医药》 2026年第4期627-631,共5页
顺铂是许多癌症治疗的一线化疗药物,但因其肾脏毒性在临床应用中受到一些限制。近年研究发现,细胞衰老在顺铂所致急性肾损伤进程中发挥关键作用。细胞衰老表现为不可逆的细胞周期停滞,衰老细胞可以通过分泌多种炎性因子及促纤维化因子,... 顺铂是许多癌症治疗的一线化疗药物,但因其肾脏毒性在临床应用中受到一些限制。近年研究发现,细胞衰老在顺铂所致急性肾损伤进程中发挥关键作用。细胞衰老表现为不可逆的细胞周期停滞,衰老细胞可以通过分泌多种炎性因子及促纤维化因子,构成衰老相关分泌表型,引起周围环境改变,进而驱动急性肾损伤向慢性肾脏病进展。因此靶向清除衰老细胞可能成为顺铂治疗期间肾脏保护的潜在治疗靶点,但其具体机制并不明确。本综述旨在阐述细胞衰老在顺铂诱导急性肾损伤及肾脏纤维化中的作用,期望能为防治顺铂毒副作用提供新的理论依据。 展开更多
关键词 急性肾损伤 肾脏纤维化 细胞衰老 顺铂
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Analysis of the SPX gene family in Vitis vinifera and Vitis amurensis and its expression under phosphorus stress 认领 引用
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作者 Xu Huang Shixiong Lu +4 位作者 Miao Shao Yongqing Feng Huimin Gou Guoping Liang Juan Mao 《Fruit Research》 2025年第1期358-371,共14页
Only a small amount of phosphorus is absorbed and utilized in the soil.The SPX(SYG1,PHO81,XPR1 acronyms)gene family is important in controlling phosphorus uptake,transport,and utilization on a molecular level.However,... Only a small amount of phosphorus is absorbed and utilized in the soil.The SPX(SYG1,PHO81,XPR1 acronyms)gene family is important in controlling phosphorus uptake,transport,and utilization on a molecular level.However,their systematic identification in grapes is still unclear.The Vitis vinifera and Vitis amurensis databases revealed a total of 37 SPX genes,with 16 VvSPX genes and 21 VaSPX genes placed on 10 chromosomes each.VvSPX and VaSPX genes are grouped into four subfamilies and contain phosphorus stress response elements such as P1BS and MBS.The highest number of genes were widely distributed in the plasma membrane,followed by the nucleus and cytoplasm.Chip data analysis showed that VvSPX16 had the highest expression level in leaves.Collinearity among intraspecifics revealed that Vitis vinifera and Vitis amurensis had a stronger collinearity relationship with Arabidopsis thaliana than Oryza sativa.Real-time quantitative PCR revealed that roots were more sensitive to low Pi than leaves under Pi stress conditions.VvSPX2,VvSPX4,VvSPX11,VaSPX11,VaSPX12,VaSPX13,and VaSPX20 showed a particularly strong response to excess Pi.VvSPX2,VvSPX4,VvSPX11,VaSPX3,VaSPX11,VaSPX13,and VaSPX21 were most highly expressed in roots at 24 h of low phosphorus stress.Phosphate deprivation dramatically increased the expression of VvSPX9,VvSPX11,VaSPX10,and VaSPX21 in both roots and leaves,suggesting that these genes might be important candidate genes for phosphate famine in grapes.This provided a reference for further research on their mechanisms of action in phosphorus stress response. 展开更多
关键词 Phosphorus stress Vitis amurensis spx geneswith Gene expression SXP gene family Vitis vinifera vvspx genes vitis vinifera vitis amurensis databases
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Long-Term Follow-Up of Percutaneous Stent Implantation for Residual Pulmonary Artery Stenosis in Pediatric Patients after Surgical Repair of Complicated Congenital Heart Diseases 认领 引用
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作者 Yifan Li Xu Huang +4 位作者 Bingyu Ma Ling Sun Shushui Wang Zhiwei Zhang Yumei Xie 《Congenital Heart Disease》 SCIE 2025年第4期463-475,共13页
Objective:The aim of the present study was to investigate long-term efficacy and safety of percutaneous stent implantation for residual pulmonary artery stenosis(PAS)in pediatric patients after surgical repair of comp... Objective:The aim of the present study was to investigate long-term efficacy and safety of percutaneous stent implantation for residual pulmonary artery stenosis(PAS)in pediatric patients after surgical repair of complicated congenital heart diseases(CHDs).Methods:All pediatric patients diagnosed with residual PAS after surgical repair of complicated CHDs between 1996 and 2020 were retrospectively enrolled in the study.Results:A total of 41 patients(30 males,11 females;median age 5.0 years,median weight 17 kg)were followed-up for a median of 7.1 years.Follow-up echocardiography results demonstrated that the target vessel diameter increased from(3.4±1.1)mm preoperatively to(6.2±1.9)mm one year post-procedure and(6.0±1.5)mm at the final follow-up(p72 mmHg)was significantly associated with long-term adverse events(p=0.024).Conclusion:Percutaneous stent implantation for residual PAS after surgical repair of complicated CHDs effectively relieves vessel stenosis,stabilizes cardiac function,and improves long-term prognosis in pediatric patients.In-stent restenosis remains an unresolved complication,necessitating further advancements in interventional strategies. 展开更多
关键词 Percutaneous stent implantation pulmonary artery stenosis children
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Dihydromyricetin reverses cognitive dysfunction in type 2 diabetic rats via inhibition of the JNK-ERS axis 认领 引用
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作者 Huijie Lv Jun Peng +3 位作者 Xu Huang Tuo Xu Tianchen Zhang Hongyan Ling 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2025年第11期1003-1023,共21页
Recent studies have demonstrated that dihydromyricetin(DHM)exerts a protective effect against central nervous system injury.Building on these findings,the present study aimed to investigate whether DHM could ameliorat... Recent studies have demonstrated that dihydromyricetin(DHM)exerts a protective effect against central nervous system injury.Building on these findings,the present study aimed to investigate whether DHM could ameliorate cognitive deficits in a type 2 diabetes mellitus(T2DM)rat model,and to explore whether this effect involved inhibition of the JNK signaling pathway and suppression of endoplasmic reticulum stress(ERS).To establish the T2DM model,Sprague Dawley(SD)rats were fed a high-fat,high-sugar diet in combination with a single intraperitoneal injection of streptozotocin(STZ).Fasting blood glucose levels were measured from tail vein samples,and cognitive performance was evaluated using the Morris water maze(MWM)and Y-maze tests.Following behavioral assessments,the animals were sacrificed by cervical dislocation,and hippocampal tissues were collected for further analysis.Histological examination using hematoxylin-eosin(H&E)staining was performed to assess hippocampal neuronal damage.Western blotting(WB)analysis was employed to quantify the expression of pro-apoptotic protein Bax and anti-apoptotic protein Bcl-2,while ELISA was conducted to measure levels of phosphorylated tau(p-tau)and amyloid-β(Aβ)in the hippocampus.After 12 weeks of oral administration of DHM(250 mg/kg/d),relevant biomarkers were re-evaluated to determine the compound's impact on cognitive function and hippocampal integrity.Additionally,rats from each group received intracerebroventricular injections of various pharmacological agents,namely,TUDCA(an ERS inhibitor),STZ,SP600125(a JNK inhibitor),and anisomycin(AMY,a JNK activator).WB analysis was further conducted to assess the expression of JNK,phosphorylated JNK(p-JNK),and ERS-associated proteins Bip and p-PERK in hippocampal tissue.The results confirmed that combining a high-fat,high-sugar diet with low-dose STZ injection for 4 weeks effectively established a T2DM model.Compared with the control group,T2DM rats exhibited significant cognitive deficits,increased neuronal apoptosis in the hippocampus,and elevated hippocampal levels of p-tau and Aβ.Notably,DHM treatment markedly reversed these pathological changes in T2DM rats,whereas it had no significant effects on control animals.Moreover,administration of TUDCA and SP600125 similarly mitigated cognitive impairment,neuronal apoptosis,and the accumulation of p-tau and Aβin diabetic rats.Conversely,activation of ERS and JNK signaling using tunicamycin(TUN)and AMY,respectively,resulted in exacerbated cognitive decline,increased neuronal apoptosis,and higher levels of p-tau and Aβ.In conclusion,these findings suggested that DHM effectively alleviated cognitive dysfunction in T2DM rats,potentially through the inhibition of JNK signaling and subsequent attenuation of ERS,thereby reducing neuronal apoptosis and the pathological accumulation of p-tau and Aβin the hippocampus. 展开更多
关键词 Dihydromyricetin Type 2 diabetes Cognitive dysfunction JNK signaling Endoplasmic reticulum stress
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Intraportal mesenchymal stem cell transplantation prevents acute liver failure through promoting cell proliferation and inhibiting apoptosis 认领 引用 被引量：13
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作者 Jian-Feng Sang Xiao-Lei Shi +4 位作者 Bin Han Tao Huang Xu Huang Hao-Zhen Ren Yi-Tao Ding 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2016年第6期602-611,共10页
BACKGROUND： Transplantation of mesenchymal stem cells （MSCs） has been regarded as a potential treatment for acute liver failure （ALF）, but the optimal route was unknown. The present study aimed to explore the mos... BACKGROUND： Transplantation of mesenchymal stem cells （MSCs） has been regarded as a potential treatment for acute liver failure （ALF）, but the optimal route was unknown. The present study aimed to explore the most effective MSCs transplantation route in a swine ALF model. METHODS： The swine ALF model induced by intravenous injection of D-Gal was treated by the transplantation of swine MSCs through four routes including intraportal injection （InP group）, hepatic intra-arterial injection （AH group）, peripheral intravenous injection （PV group） and intrahepatic injection （IH group）. The living conditions and survival time were recorded. Blood samples before and after MSCs trans- plantation were collected for the analysis of hepatic function. The histology of liver injury was interpreted and scored in terminal samples. Hepatic apoptosis was detected by TUNEL assay. Apoptosis and proliferation related protein expressions including cleaved caspase-3, survivin, AKT, phospho-AKT （Ser473）, ERK and phospho-ERK （Tyr204） were analyzed by Western blotting. RESULTS： The average survival time of each group was 10.7± 1.6 days （InP）, 6.0±0.9 days （AH）, 4.7±1.4 days （PV）, 4.3± 0.8 days （IH）, respectively, when compared with the average survival time of 3.8±0.8 days in the D-Gal group. The survival rates between the InP group and D-Gal group revealed a statistically significant difference （P〈0.01）. Pathological and biochemical analysis showed that liver damage was the worst in the D-Gal group, while less injury in the InP group. Histopathological scores revealed a significant decrease in the InP group （3.17±1.04, P〈0.01） and AH group （8.17±0.76, P〈0.05） as compared with that in the D-Gal group （11.50±1.32）. The apoptosis rate in the InP group （25.0%±3.4%, P〈0.01） and AH group （40.5%±1.0% , P〈0.05） was lower than that in the D-Gal group （70.6%±8.5%）. The expression of active caspase-3 was inhibited, while the expression of survivin, AKT, phospho- AKT （Ser473）, ERK and phospho-ERK （Tyr204） was elevated in the InP group. CONCLUSIONS： Intraportal injection was superior to other pathways for MSC transplantation. Intraportal MSC trans- plantation could improve liver function, inhibit apoptosis and prolong the survival time of swine with ALE The transplanted MSCs may participate in liver regeneration via promoting cell proliferation and suppressing apoptosis during the initial stage of ALE 展开更多
关键词 mesenchymal stem cells stem cell transplantation acute liver failure apoptosis regeneration
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The mechanisms of grain growth of Mg alloys:A review 认领 引用 被引量：13
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作者 Qinghua Chen Ruinan Chen +6 位作者 Jian Su Qingsong He Bin Tan Chao Xu Xu Huang Qingwei Dai Jian Lu 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2022年第9期2384-2397,共14页
Grain growth directly influences the plasticity and strength of Mg alloys.As the grain size decreases from the microscale to the nanoscale,the plasticity of Mg alloys continually increases,whereas the strength first i... Grain growth directly influences the plasticity and strength of Mg alloys.As the grain size decreases from the microscale to the nanoscale,the plasticity of Mg alloys continually increases,whereas the strength first increases and later decreases.These trends are observed because the plastic deformation mechanism changes from dislocation–twinning dominance to grain boundary dominance.In this study,the factors influencing grain growth,such as the temperature of plastic deformation/annealing,second-phase particles and solute atoms,are examined to aid effective control of the grain size.Additionally,the mechanisms of grain growth,typically induced by strain and thermal activation,are clarified.Strain-induced grain boundary migration is attributable to the difference in the strain energy stored in adjacent grains with high-density dislocations.Heat-induced grain boundary migration is driven by the difference in the energy of the grain boundary/subgrain boundary and boundary curvature.Abnormal grain growth can be induced by anisotropy of the strain energy,anisotropy of the grain boundary mobility,depinning of the second phase and high misorientation gradient. 展开更多
关键词 Mg alloys Grain growth Mechanical properties Microstructure
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Microstructure design of advanced magnesium-air battery anodes 认领 引用 被引量：8
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作者 Xu Huang Qingwei Dai +4 位作者 Qing Xiang Na Yang Gaopeng Zhang Ao Shen Wanming Li 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第2期443-464,共22页
Metal-air battery is an environmental friendly energy storage system with unique open structure.Magnesium(Mg)and its alloys have been extensively attempted as anodes for air batteries due to high theoretical energy de... Metal-air battery is an environmental friendly energy storage system with unique open structure.Magnesium(Mg)and its alloys have been extensively attempted as anodes for air batteries due to high theoretical energy density,low cost,and recyclability.However,the study on Mg-air battery(MAB)is still at the laboratory level currently,mainly owing to the low anodic efficiency caused by the poor corrosion resistance.In order to reduce corrosion losses and achieve optimal utilization efficiency of Mg anode,the design strategies are reviewed from microstructure perspectives.Firstly,the corrosion behaviors have been discussed,especially the negative difference effect derived by hydrogen evolution.Special attention is given to the effect of anode micro-structures on the MAB,which includes grain size,grain orientation,second phases,crystal structure,twins,and dislocations.For further improvement,the discharge performance,long period stacking ordered phase and its enhancing effect are considered.Meanwhile,given the current debates over Mg dendrites,the potential risk,the impact on discharge,and the elimination strategies are discussed.Microstructure control and single crystal would be promising ways for MAB anode. 展开更多
关键词 Magnesium Air battery Anode Microstructure Anodic efficiency
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Development of Ti-Al-Ta-Nb-(Re)near-αhigh temperature titanium alloy:Microstructure,thermal stability and mechanical properties 认领 引用 被引量：8
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作者 Juan Li Yaqun Xu +2 位作者 Wenlong Xiao Chaoli Ma Xu Huang 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2022年第14期1-11,共11页
Mechanical properties and microstructural stability under the service temperature are important to the high temperature titanium alloy.In order to evaluate the potential in increase the service temperature of Ti alloy... Mechanical properties and microstructural stability under the service temperature are important to the high temperature titanium alloy.In order to evaluate the potential in increase the service temperature of Ti alloy,two near-αTi alloys with high content of Al asα-stabilizer and Ta,Nb and/or Re asβ-stabilizers were designed and prepared by ingot metallurgy and thermomechanical processing,and the microstructure and mechanical properties before and after thermal exposure at 650℃ for 100 h were characterized.The results indicated that due to the weakβ-stabilizing ability of Ta and Nb elements,only a small amount ofβphase was formed in Ti-10Al-4Ta-2Nb alloy.With a trace Re addition,theβphase was obviously increased in Ti-10Al-4Ta-2Nb-0.25Re,indicating that the Re was a strongβ-stabilizer.Under the same thermomechanical conditions,the Re addition decreased the volume fraction of primaryα(αp)phase and refined the secondaryα(αs)phase evidently.The primaryαphase presented an obvious core-shell structure in the Ti-10Al-4Ta-2Nb alloy,with higher Al concentration in the shell.While the core-shell structure was not obvious in the Re-containing alloy due to the Re decreases the diffusion of Al,Ta and Nb elements.A large number of orderedα2precipitates can be observed in theαpandαs phases of two alloys.Theα2precipitates continuously grew up during thermal exposure,however,their growth rate in theαsphase of Re-containing alloy were lower than that of Ti-10Al-4Ta-2Nb alloy.Although plenty of orderedα2precipitates formed in the Ti-10Al-4Ta-2Nb alloy,the alloy had a certain plasticity at room temperature.The trace Re addition evidently increased the tensile strength but caused the decrease of the plasticity.After thermal exposure,the strength was further increased,while the plasticity was decreased for both of alloys. 展开更多
关键词 Titanium alloy High temperature Microstructure Mechanical properties α2precipitates Thermal exposure
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Different distributions of interstitial cells of Cajal and platelet-derived growth factor receptor-α positive cells in colonic smooth muscle cell/interstitial cell of Cajal/plateletderived growth factor receptor-α positive cell syncytium in mice 认领 引用 被引量：9
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作者 Chen Lu Xu Huang +5 位作者 Hong-Li Lu Shao-Hua Liu Jing-Yu Zang Yu-Jia Li Jie Chen Wen-Xie Xu 《World Journal of Gastroenterology》 SCIE CAS 2018年第44期4989-5004,共16页
AIM To investigate the distribution and function of interstitialcells of Cajal(ICCs) and platelet-derived growth factor receptor-α positive(PDGFRα+) cells in the proximal and distal colon.METHODS The comparison of c... AIM To investigate the distribution and function of interstitialcells of Cajal(ICCs) and platelet-derived growth factor receptor-α positive(PDGFRα+) cells in the proximal and distal colon.METHODS The comparison of colonic transit in the proximal and distal ends was performed by colonic migrating motor complexes(CMMCs). The tension of the colonic smooth muscle was examined by smooth muscle spontaneous contractile experiments with both ends of the smooth muscle strip tied with a silk thread. Intracellular recordings were used to assess electrical field stimulation(EFS)-induced inhibitory junction potentials(IJP) on the colonic smooth muscle. Western blot analysis was used to examine the expression levels of ICCs and PDGFRα in the colonic smooth muscle.RESULTS Treatment with NG-nitro-L-arginine methyl ester hydrochloride(L-NAME) significantly increased the CMMC frequency and spontaneous contractions, especially in the proximal colon, while treatment with MRS2500 increased only distal CMMC activity and smooth muscle contractions. Both CMMCs and spontaneous contractions were markedly inhibited by NPPB, especially in the proximal colon. Accordingly, CyPPA sharply inhibited the distal contraction of both CMMCs and spontaneous contractions. Additionally, the amplitude of stimulationinduced nitric oxide(NO)/ICC-dependent slow IJPs(sIJPs) by intracellular recordings from the smooth muscles in the proximal colon was larger than that in the distal colon, while the amplitude of electric field stimulationinduced purinergic/PDGFRα-dependent fast IJPs(fIJPs) in the distal colon was larger than that in the proximal colon. Consistently, protein expression levels of c-Kit and anoctamin-1(ANO1) in the proximal colon were much higher, while protein expression levels of PDGFRα and small conductance calcium-activated potassium channel 3(SK3) in the distal colon were much higher.CONCLUSION The ICCs are mainly distributed in the proximal colon and there are more PDGFRα+ cells are in the distal colon, which generates a pressure gradient between the two ends of the colon to propel the feces to the anus. 展开更多
关键词 Interstitial cells of Cajal Platelet-derived growth factor receptor-α positive cells Smooth muscle cell/interstitial cell of Cajal/platelet-derived growth factor receptor-α positive cell syncytium Nitric oxide Purine
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Hydrogen sulfide-induced enhancement of gastric fundus smooth muscle tone is mediated by voltagedependent potassium and calcium channels in mice 认领 引用 被引量：5
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作者 Xiang-Min Meng Xu Huang +4 位作者 Chun-Mei Zhang Dong-Hai Liu Hong-Li Lu Young-chul Kim Wen-Xie Xu 《World Journal of Gastroenterology》 SCIE CAS 2015年第16期4840-4851,共12页
AIM:To investigate the effect of hydrogen sulfide(H2S)on smooth muscle motility in the gastric fundus.METHODS:The expression of cystathionineβ-synthase(CBS)and cystathionineγ-lyase(CSE)in cultured smooth muscle cell... AIM:To investigate the effect of hydrogen sulfide(H2S)on smooth muscle motility in the gastric fundus.METHODS:The expression of cystathionineβ-synthase(CBS)and cystathionineγ-lyase(CSE)in cultured smooth muscle cells from the gastric fundus was examined by the immunocytochemistry technique.The tension of the gastric fundus smooth muscle was recorded by an isometric force transducer under the condition of isometric contraction with each end of the smooth muscle strip tied with a silk thread.Intracellular recording was used to identify whether hydrogen sulfide affects the resting membrane potential of the gastric fundus in vitro.Cells were freshly separated from the gastric fundus of mice using a variety of enzyme digestion methods and whole-cell patch-clamp technique was used to find the effects of hydrogen sulfide on voltage-dependent potassium channel and calcium channel.Calcium imaging with fura-3AM loading was used to investigate the mechanism by which hydrogen sulfide regulates gastric fundus motility in cultured smooth muscle cells.RESULTS:We found that both CBS and CSE were expressed in the cul tured smooth muscle cel ls from the gastric fundus and that H2S increased the smooth muscle tension of the gastric fundus in mice at low concentrations.In addition,nicardipine and aminooxyacetic acid(AOAA),a CBS inhibitor,reduced the tension,whereas Nω-nitro-L-arginine methyl ester,a nonspecific nitric oxide synthase,increased the tension.The AOAA-induced relaxation was significantly recovered by H2S,and the Na HS-induced increase in tonic contraction was blocked by 5 mmol/L4-aminopyridine and 1μmol/L nicardipine.Na HS significantly depolarized the membrane potential and inhibited the voltage-dependent potassium currents.Moreover,Na HS increased L-type Ca2+currents and caused an elevation in intracellular calcium([Ca2+]i).CONCLUSION:These findings suggest that H2S may be an excitatory modulator in the gastric fundus in mice.The excitatory effect is mediated by voltagedependent potassium and L-type calcium channels. 展开更多
关键词 Gastric fundus smooth muscle Hydrogensulfide Tension Voltage-dependent potassium channel L-type calcium channel
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Rapid and simultaneous determination of imidazolium and pyridinium ionic liquid cations by ion-pair chromatography using a monolithic column 认领 引用 被引量：16
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作者 Xu Huang Hong Yu Ying Jie Dong 《Chinese Chemical Letters》 SCIE CAS CSCD 2012年第7期843-846,共4页
A method for rapid and simultaneous determination of imidazolium and pyridinium ionic liquid cations by ion-pair chromatography with ultraviolet detection was developed. Chromatographic separations were performed on a... A method for rapid and simultaneous determination of imidazolium and pyridinium ionic liquid cations by ion-pair chromatography with ultraviolet detection was developed. Chromatographic separations were performed on a reversed-phase silica-based monolithic column using 1-heptanesulfonic acid sodium-acetonitrile as mobile phase. The effects of ion-pair reagent and acetonitrile concentration on retention of the cations were investigated. The retention times of the cations accord with carbon number rule. The method has been successfully applied to the determination of four ionic liquids synthesized by organic chemistry laboratory. 展开更多
关键词 Ionic liquids Ion-pair chromatography Monolithic column Ultraviolet detection
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Burning products of TA15 titanium alloy by friction oxygen concentration method 认领 引用 被引量：5
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作者 Nan Sui Guang-Bao Mi +2 位作者 Meng-Qi Yan Jing-Xia Cao Xu Huang 《Rare Metals》 SCIE EI CAS CSCD 2018年第11期952-960,共9页
The microstructural characteristics, elemental distribution law and microscopic formation mechanism of the burning products of TA15 titanium alloy were investigated by friction oxygen concentration method, associated ... The microstructural characteristics, elemental distribution law and microscopic formation mechanism of the burning products of TA15 titanium alloy were investigated by friction oxygen concentration method, associated with in situ observation, X-ray diffraction(XRD),scanning electron microscopy(SEM) and energy-dispersive spectroscopy(EDS) analyses, providing the thoughts to improve fireproof property. The results show that, when the friction contact pressure(p) is 0.20 MPa and oxygen concentration of premixed air flow(c) is 60 vol%, TA15 titanium alloy produces violent sparks and presents dazzling white light during combustion. The generated products after burning are mainly TiOand small amount of AlOoxides. Four distinct zones form from the combustion surface to the alloy matrix, and they are in the sequence of combustion zone, fusion zone, heat-affected zone and transition zone. Further, combustion zone is composed of TiOand A1203 compounds, containing obvious cracks. In the fusion zone, discontinuous oxygenrich Al-based solid solution forms, and the elemental distribution has strong volatility. In the heat-affected zone,there are abundant of Ti-based solid solution and small amount of Al-and Mo-based solid solution. Transition zone is made of lamellar structure. Two technical approaches are given to prevent oxygen diffusion inside the reaction zone and reaction-affected zone. On the one hand,the content of Al is designed as the upper limit of alloy composition; on the other hand, fireproof coatings are deposited on the surface of the alloy. 展开更多
关键词 Friction oxygen concentration method TA15 titanium alloy Burning products Microstructure Titanium fire
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Atrial natriuretic peptide signal pathway upregulated in stomach of streptozotocin-induced diabetic mice 认领 引用 被引量：5
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作者 Zhang-Xun Qiu Bing Mei +6 位作者 Yi-Song Wu Xu Huang Zuo-Yu Wang Yan-Fei Han Hong-Li Lu Young-Chul Kim Wen-Xie Xu 《World Journal of Gastroenterology》 SCIE CAS 2010年第1期48-55,共8页
AIM:To investigate atrial natriuretic peptide(ANP)secretion from gastric mucosa and the relationship between the ANPatriuretic peptide receptor type A(NPR-A)pathway and diabetic gastroparesis.METHODS:Male imprinting c... AIM:To investigate atrial natriuretic peptide(ANP)secretion from gastric mucosa and the relationship between the ANPatriuretic peptide receptor type A(NPR-A)pathway and diabetic gastroparesis.METHODS:Male imprinting control region(ICR)mice(4 wk old)were divided into two groups:control mice,and streptozotocin-induced diabetic mice.Eight weeks after injection,spontaneous gastric contraction was recorded by using physiography in control and streptozotocin-induced diabetic mice.The ANP-positive cells in gastric mucosa and among dispersed gastric epithelial cells were detected by using immunohistochemistry and flow cytometry,respectively.ANP and natriureticpeptide receptor type A(NPR-A)gene expression in gastric tissue was observed by using the reverse transcriptase polymerase chain reaction.RESULTS:The frequency of spontaneous gastric contraction was reduced from 12.9±0.8 cycles/min in the control group to 8.4±0.6 cycles/min in the diabetic mice(n=8,P<0.05).However,the amplitude of contraction was not significantly affected in the diabetic group.The depletion of interstitial cells of Cajal in the gastric muscle layer was observed in the diabetic mice.ANP-positive cells were distributed in the gastric mucosal layer and the density index of ANP-positive cells was increased from 20.9±2.2 cells/field in control mice to 51.8±2.9 cells/field in diabetic mice(n=8,P<0.05).The percentage of ANP-positive cells among the dispersed gastric epithelial cells was increased from 10.0%±0.9%in the control mice to 41.2%±1.0%in the diabetic mice(n=3,P<0.05).ANP and NPR-A genes were both expressed in mouse stomach,and the expression was significantly increased in the diabetic mice.CONCLUSION:These results suggest that the ANP/NPR-A signaling pathway is upregulated in streptozotocin-induced diabetic mice,and contributes to the development of diabetic gastroparesis. 展开更多
关键词 Diabetes mellitus Atrial natriuretic peptide Gastric mucosa Gastroparesis
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