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- Recombinant tissue plasminogen activator protects neurons after intracerebral hemorrhage through activating the PI3K/AKT/mTOR pathway 认领 引用 被引量：1
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- 作者 Jie Jing Shiling Chen +7 位作者 Xuan Wu Jingfei Yang Xia Liu Jiahui Wang Jingyi Wang Yunjie Li Ping Zhang Zhouping Tang 《Neural Regeneration Research》 SCIE CAS CSCD 2026年第4期1574-1585,共12页
- Recombinant tissue plasminogen activator is commonly used for hematoma evacuation in minimally invasive surgery following intracerebral hemorrhage.However,during minimally invasive surgery,recombinant tissue plasminog... Recombinant tissue plasminogen activator is commonly used for hematoma evacuation in minimally invasive surgery following intracerebral hemorrhage.However,during minimally invasive surgery,recombinant tissue plasminogen activator may come into contact with brain tissue.Therefore,a thorough assessment of its safety is required.In this study,we established a mouse model of intracerebral hemorrhage induced by type VII collagenase.We observed that the administration of recombinant tissue plasminogen activator without hematoma aspiration significantly improved the neurological function of mice with intracerebral hemorrhage,reduced pathological damage,and lowered the levels of apoptosis and autophagy in the tissue surrounding the hematoma.In an in vitro model of intracerebral hemorrhage using primary cortical neurons induced by hemin,the administration of recombinant tissue plasminogen activator suppressed neuronal apoptosis,autophagy,and endoplasmic reticulum stress.Transcriptome sequencing analysis revealed that recombinant tissue plasminogen activator upregulated the phosphoinositide 3-kinase/RAC-alpha serinehreonine-protein kinase/mammalian target of rapamycin pathway in neurons.Moreover,the phosphoinositide 3-kinase inhibitor LY294002 abrogated the neuroprotective effects of recombinant tissue plasminogen activator in inhibiting excessive apoptosis,autophagy,and endoplasmic reticulum stress.Furthermore,to specify the domain of recombinant tissue plasminogen activator responsible for its neuroprotective effects,various inhibitors were used to target distinct domains.It has been revealed that the epidermal growth factor receptor inhibitor AG-1478 reversed the effect of recombinant tissue plasminogen activator on the phosphoinositide 3-kinase/RAC-alpha serinehreonineprotein kinase/mammalian target of rapamycin pathway.These findings suggest that recombinant tissue plasminogen activator exerts a direct neuroprotective effect on neurons following intracerebral hemorrhage,possibly through activation of the phosphoinositide 3-kinase/RAC-alpha serinehreonine-protein kinase/mammalian target of rapamycin pathway. 展开更多
- 关键词 apoptosis autophagy endoplasmic reticulum stress epidermal growth factor intracerebral hemorrhage mammalian target of rapamycin minimally invasive surgery phosphoinositide 3-kinase RAC-alpha serinehreonine-protein kinase recombinant tissue plasminogen activator
- Cucurbit[7]uril-confined cascade assembly of cyclodextrin phosphor derivative achieving multicolor delayed luminescence for information encryption 认领 引用
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- 作者 Jie Niu Xuan Wu +4 位作者 Jie Yu Zhuo Lei Ying-Ming Zhang Li-Hua Wang Yu Liu 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第5期332-338,共7页
- Macrocyclic cascade supramolecular assembly could significantly enhance the fluorescence/phosphorescence resonance energy transfer(F/PRET)efficiency through macrocyclic and spatial dual confinement effect.Herein,we re... Macrocyclic cascade supramolecular assembly could significantly enhance the fluorescence/phosphorescence resonance energy transfer(F/PRET)efficiency through macrocyclic and spatial dual confinement effect.Herein,we reported a cascade supramolecular assembly containing6-bromoisoquinolinium-modified permethylated cyclodextrin(BQ-PCD),cucurbit[7]uril(CB[7]),and tetra(4-sulfonatophenyl)porphyrin(TPPS),in which the enhanced PRET from 6-bromoisoquinolinium(BQ)to TPPS could be achieved through the dual macrocyclic confinement for multicolor delayed luminescence and information encryption.In TPPS⊂BQ-PCD⊂CB[7],pure organic room temperature phosphorescence of BQ-PCD at 530 nm is induced by CB[7]macrocyclic confinement,which further transferred to TPPS via spatial confinement,achieving delayed fluorescence at 645 and 715 nm with high PRET efficiency and quantum yield(17.9%).Meanwhile,reversible TPPS concentration-dependent multicolor luminescence was achieved in presence of competitive guest(methionine peptide),followed by porphyrin-photosensitization process,being applied in information encryption.This research presents a facile strategy for efficient PRET through macrocyclic cascade confinement assembly. 展开更多
- 关键词 Macrocyclic confinement effect Cascade assembly Phosphorescence resonance energy transfer Delayed multicolor luminescence Guest competitive binding Information encryption
- Ultrasound/magnetic field dual-responsive Fe3O4/glucose oxidase catalytic microbubbles for enhanced bacterial biofilm elimination 认领 引用
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- 作者 Chi Zhang Dou Wang +6 位作者 Liang Lu Feng-Jiao Xu Fan-Sen Xu Xuan Wu Xiao-Xiao Xu Xiao Li Li-Hui Yuwen 《Biomedical Engineering Communications》 CAS 2026年第1期4-12,共9页
- Background:The bacterial biofilm poses a significant challenge to traditional antibiotic therapy.There is a great need to develop novel antibiofilm agents combined with biofilm disrupting and bacteria-killing without ... Background:The bacterial biofilm poses a significant challenge to traditional antibiotic therapy.There is a great need to develop novel antibiofilm agents combined with biofilm disrupting and bacteria-killing without the dependence of antibiotic.Methods:Herein,we prepared ultrasound/magnetic field-responsive ferroferric oxide nanoparticles(Fe3O4)/glucose oxidase microbubbles(FGMB)to form a cascade catalytic system for effective removing methicillin-resistant Staphylococcus aureus biofilms.FGMB were prepared through interfacial self-assembly of Fe3O4 nanoparticles(NPs)and glucose oxidase(GOx)at the gas-liquid interface stabilized by surfactants.Under ultrasound/magnetic field stimulation,FGMB disrupted biofilm architecture through microbubble collapse-induced microjets and magnetically driven displacement.Simultaneously,ultrasound-triggered rupture of FGMB released GOx and Fe3O4 NPs.Glucose can be oxidized by GOx to generate gluconic acid and hydrogen peroxide which was subsequently catalyzed into hydroxyl radicals by Fe3O4 NPs,enabling chemical eradication of biofilm-embedded bacteria.Results:Optical microscopy images demonstrated that FGMB have spherical structure with average size of approximately 17μm.FGMB showed a 65.4%decrease in methicillin-resistant Staphylococcus aureus biofilm biomass and 1.1 log bacterial inactivation efficiency(91.2%),suggesting effective biofilm elimination.In vitro experimental results also indicate that FGMB have good biocompatibility.Conclusion:This antibiofilm strategy integrated dual modes of physical biofilm disruption with chemical bacteria-killing shows great potential as a versatile,non-resistant strategy for bacterial biofilm elimination. 展开更多
- 关键词 bacterial biofilm ultrasound magnetic field catalytic microbubbles mechanical disruption chemical degradation
- Cell polarization in ischemic stroke: molecular mechanisms and advances 认领 引用 被引量：18
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- 作者 Yuanwei Li Xiaoxiao Xu +5 位作者 Xuan Wu Jiarui Li Shiling Chen Danyang Chen Gaigai Li Zhouping Tang 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第3期632-645,共14页
- Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modu... Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke. 展开更多
- 关键词 astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke
- pH-responsive chiral supramolecular cysteine-Zn2+-indocyanine green assemblies for triple-level chirality-specific anti-tumor efficacy 认领 引用 被引量：1
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- 作者 Qianyun Ye Yuanyuan Liang +5 位作者 Yuhe Yuan Xiaohuan Sun Liqi Zhu Xuan Wu Jie Han Rong Guo 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第5期289-296,共8页
- Chirality,ubiquitous in living matter,plays vital roles in a series of physiological processes.The clarification of the multiple functions of chirality in bioapplications may provide innovative methodologies for engin... Chirality,ubiquitous in living matter,plays vital roles in a series of physiological processes.The clarification of the multiple functions of chirality in bioapplications may provide innovative methodologies for engineering anti-tumor agents.Nevertheless,the related research has been rarely explored.In this study,the chiral supramolecular l/d-cysteine(Cys)-Zn2+-indocyanine green(ICG)nanoparticles were constructed through the coordination interaction between l/d-Cys and Zn2+,followed by the encapsulation of ICG.Experimental findings revealed that the d-Cys-Zn2+-ICG exhibited 17.31 times higher binding affinity toward phospholipid-composed liposomes compared to l-Cys-Zn2+-ICG.Furthermore,driven by chiralityspecific interaction,a 2.07 folds greater cellular internalization of d-Cys-Zn2+-ICG than l-Cys-Zn2+-ICG was demonstrated.Additionally,the triple-level chirality-dependent photothermal,photodynamic and Zn2+releasing anti-tumor effects of l/d Cys-Zn2+-ICG in vitro were verified.As a result,the d-formed nanoparticles achieved 1.93 times higher anti-tumor efficiency than the l-formed ones.The triple-level chirality-mediated anti-tumor effect highlighted in this study underscores the enormous potential of chirality in biomedicine and holds substantial significance in improving cancer therapeutic efficacy. 展开更多
- 关键词 Chirality pH-responsiveness Photothermal therapy Photodynamic therapy Zn2+release
- Conceptual design report of the Super Tau-Charm Facility:the accelerator 认领 引用 被引量：1
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- 作者 Xiao-Cong Ai Liu-Pan An +451 位作者 Shi-Zhong An Yu Bai Zheng-He Bai Olga Bakina Jian-Cong Bao Varvara Batozskaya Anastasios Belias Maria Enrica Biagini Li-Gong Bian Denis Bodrov Anton Bogomyagkov Manuela Boscolo Igor Boyko Ze-Xin Cao Serkant Cetin Marina Chadeeva Ming-Xuan Chang Qin Chang Dian-Yong Chen Fang-Zhou Chen Hai Chen Hua-Xing Chen Jin-Hui Chen Long Chen Long-Bin Chen Qi Chen Qu-Shan Chen Shao-Min Chen Wei Chen Ying Chen Zhi Chen Shan Cheng Si-Bo Cheng Tong-Guang Cheng Lian-Rong Dai Ling-Yun Dai Xin-Chen Dai Achim Denig Igor Denisenko Denis Derkach Heng-Tong Ding Ming-Hui Ding Xiao Ding Liao-Yuan Dong Yong Du Prokhor Egorov Kuan-Jun Fan Si-Yuan Fan Shuang-Shi Fang Zhu-Jun Fang Song Feng Xu Feng Hai-Bing Fu Jun Gao Yuan-Ning Gao Zi-Han Gao Cong Geng Li-Sheng Geng Hai-Liang Gong Jia-Ding Gong Li Gong Shao-Kun Gong Sergi Gonzàlez-Solís Bo-Xing Gou Duan Gu Hao Guo Jun Guo Teng-Jun Guo Xin-Heng Guo Yu-Hui Guo Yu-Ping Guo Zhi-Hui Guo Selcuk Haciomeroglu Eiad Hamwi Cheng-Dong Han Ting-Ting Han Xi-Qing Hao Chong-Chao He Ji-Bo He Tian-Long He Xiao-Gang He Masahito Hosaka Kai-Wen Hou Zhi-Long Hou Dong-Dong Hu Hai-Ming Hu Hao Hu Qi-Peng Hu Tong-Ning Hu Xiao-Cheng Hu Yu Hu Zhen Hu Da-Zhang Huang Fei Huang Guang-Shun Huang Liang-Sheng Huang Peng-Wei Huang Rui-Xuan Huang Xing-Tao Huang Xue-Lei Huang Zhi-Cheng Huang Wang Ji Peng-Kun Jia Sen Jia Ze-Kun Jia Hong-Ping Jiang Hou-Bing Jiang Jian-Bin Jiao Ming-Jie Jin Su-Ping Jin Yi Jin Daekyoung Kang Xian-Wei Kang Xiao-Lin Kang Leonid Kaptari Onur Bugra Kolcu Ivan Koop Evgeniy Kravchenko Yury Kudenko Meike Küßner Yong-Bin Leng Eugene Levichev Chao Li Chun-Yuan Li Chun-Hua Li Hai Tao Li Hai-Bo Li Hang-Zhou Li Heng-Ne Li Hong-Lei Li Hui-Jing Li Hui-Lin Li Jia-Rong Li Jin Li Lei Li Min Li Pei-Rong Li Pei-Lian Li Ren-Kai Li Sang-Ya Li Shu Li Teng Li Tian-You Li Wei-Wei Li Wen-Jun Li Xin Li Xin-Qiang Li Xin-Bai Li Xuan Li Xun-Feng Li Yan-Feng Li Ya-Xuan Li Ying Li Yu-Bo Li Jian Liang Xiao Liang Yu Liang Ze-Rui Liang Chuang-Xin Lin De-Xu Lin Ting Lin Yu-Gen Lin Chao Liu Chao Liu Chia-Wei Liu Gang-Wen Liu Hang Liu Hong-Bang Liu Jian-Bei Liu Jian-Dang Liu Lang-Tian Liu Liang-Chen Liu Ming-Yi Liu Shu-Bin Liu Tao Liu Tian-Bo Liu Xiang Liu Xiao-Yu Liu Xin Liu Xu-Yang Liu Yan-Rui Liu Yan-Lin Liu Yan-Wen Liu Yi Liu Yuan Liu Zhan-Wei Liu Zhao-Feng Liu Zhi-Qing Liu Zi-Rui Liu Zuo-Wei Liu Cai-Dian Lu Miao-Ran Lu Peng-Cheng Lu Yu Lu Qing Luo Tao Luo Tao Luo Xiao-Feng Luo Hui-Hui Lv Shuo-Tian Lyu Xiao-Rui Lyu Bo-Qiang Ma Cheng-Long Ma Shao-Hang Ma Teng Ma Wen-Bin Ma Yu Meng Meng-Xu Fan Xue-Ce Miao Mauro Migliorati Catia Milardi Taisiya Mineeva Yi-Hao Mo Hector Gisbert Mullor Elaf Musa Satoshi Nakamura Alexey Nefediev Yuan-Cun Nie Kazuhito Ohmi MPadmanath Pavel Pakhlov Jian Pang Emilie Passemar Guo-Xi Pei Hua Pei Hai-Ping Peng Liang Peng Rong-Gang Ping Bernard Pire Vindhyawasini Prasad Bin-Bin Qi Zhi-Jun Qi Yi Qian Cong-Feng Qiao Jia-Jia Qin Long-Yu Qin Qin Qin Xiao-Shuai Qin Fedor Ratnikov Craig Roberts Antonio Rodríguez-Sánchez Yury Rogovsky Platon Rogozhin Pablo Roig Man-Qi Ruan Jorge Segovia Feng-Lei Shang Lei Shang Jian-Feng Shangguan Ding-Yu Shao Ming Shao Zhuo-Xia Shao Cheng-Ping Shen Hong-Fei Shen Xiao-Min Shen Zhong-Tao Shen Cai-Tu Shi Jia-Lei Shi Rui-Xiang Shi Yu-Kun Shi Zong-Guo Si Luiz Vale Silva Mikhail Skamarokha Jun-Chao Su Guang-Bao Sun Jun-Feng Sun Kun Sun Li Sun Ming-Kai Sun Rui Sun Xu-Lei Sun Jing-Yu Tang Yin-Gao Tang Ze-Bo Tang Wei Tao Valery Telnov Jia-Xiu Teng Yuriy Tikhonov Cheng-Ying Tsai Timofey Uglov Vincenzo Vagnoni German Valencia Guan-Yue Wan An-Xin Wang Bin Wang Cheng-Zhe Wang En Wang Hong-Jin Wang Jia Wang Jie Wang Jun-Zhang Wang Lei Wang Lei Wang Lin Wang Qian Wang Qian Wang Sheng-Quan Wang Sheng-Yuan Wang Shi-Kang Wang Wei Wang Wei-Ping Wang Xiang-Peng Wang Xia-Yu Wang Xiong-Fei Wang Ya-Qian Wang Yu-Ming Wang Yu-Hao Wang Zeren Simon Wang Zhi Wang Zhi-Gang Wang Zhi-Yong Wang Zi-Yu Wang Zi-Rui Wang Bing-Feng Wei Shao-Qing Wei Shu-Yi Wei Xiao-Min Wei Ya-Jing Wei Ye-Long Wei Ulrich Wiedner Jia-Jun Wu Jun Wu Qun Wu Sang Wu Xin Wu Xing-Gang Wu Xuan Wu Yong-Cheng Wu Yu-Sheng Wu Lei Xia Zhi-Gang Xiao Chun-Jie Xie Kai-Bo Xie Zi-Yu Xiong Ji Xu Lai-Lin Xu Shu-Sheng Xu Xin Xu Yue Xu Liang Yan Wen-Biao Yan Xue-Qing Yan Chi Yang Hai-Jun Yang Hong-Tao Yang Jun Yang Peng-Hui Yang Shuai Yang Tao Yang Wei-Hua Yang Xing-Hua Yang Xue-Ting Yang Yue-Ling Yang Zhen-Wei Yang Zhong-Juan Yang De-Liang Yao Zao-Chen Ye Kai Yi Li Yi Li-Xin Yin Zheng-Yun You Chen Yu Ze Yu Jing Yuan You-Jin Yuan Nefedov Yury Yi-Feng Zeng Wang-Mei Zha Ai-Lin Zhang Ding-Yue Zhang Guang-Yi Zhang Guo-Heng Zhang Hai-Yan Zhang Hao-Ran Zhang Hong-Hao Zhang Hui-Bin Zhang Jia-Lian Zhang Jian-Rong Zhang Jian-Hui Zhang Jian-Yu Zhang Jie-Lei Zhang Lei Zhang Liang Zhang Ling-Hua Zhang Lin-Hao Zhang Ning Zhang Qiu-Yan Zhang Quan-Zheng Zhang Rui Zhang Rui-Yang Zhang Shao-Ru Zhang Sheng-Hui Zhang Shu-Lei Zhang Wen-Chao Zhang Xiao-Yang Zhang Xiao-Ming Zhang Xiao-Tao Zhang Xin Zhang Xin-Hui Zhang Yan-Xi Zhang Ya-Teng Zhang Yi-Hao Zhang Yi-Fei Zhang Yu Zhang Yu Zhang Yu-Mei Zhang Zhen-Yu Zhang Zhi-Qing Zhang Zhi-Cai Zhang Jia-Yao Zhao Ming-Gang Zhao Qiang Zhao Rui-Guang Zhao Yang-Cheng Zhao Ze-Xuan Zhao Zheng-Guo Zhao Alexey Zhemchugov Bo Zheng Jing-Xin Zheng Liang Zheng Ran Zheng Xu-Chang Zheng Yang-Heng Zheng Bin Zhong Dai-Cui Zhou De-Min Zhou Hang Zhou Hao Zhou Jian Zhou Jian-Xin Zhou Qin-Song Zhou Shi-Yu Zhou Xiang Zhou Xiao-Kang Zhou Xiao-Rong Zhou Ya-Jin Zhou Yi Zhou Yi-Mei Zhou Ze-Ran Zhou Bing Zhu Jing-Yu Zhu Jing-Ya Zhu Lin Zhu Rui-Lin Zhu Xing-Hao Zhu Ying-Chun Zhu Zian Zhu Mikhail Zobov Yang Zong Bing-Song Zou Ye Zou Jian Zu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2025年第12期8-177,共170页
- Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy... Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy physics in the last two decades,a new-generation Tau-Charm factory,called the Super Tau-Charm Facility(STCF),has been actively promoted by the particle physics community in China.STCF has the potential to address fundamental questions such as the essence of color confinement and the matter-antimatter asymmetry within the next decades.The main design goals of the STCF are a center-of-mass energy ranging from 2 to 7 GeV and a luminosity surpassing 5×1034cm−2s−1that is optimized at a center-of-mass energy of 4 GeV,which is approximately 50 times that of the currently operating Tau-Charm factory-BEPCII.The STCF accelerator has two main parts:a double-ring collider with a crab-waist collision scheme and an injector that provides top-up injections for both electron and positron beams.As a typical third-generation electron-positron circular collider,the STCF accelerator faces many challenges in both accelerator physics and technology.In this paper,the conceptual design of the STCF accelerator complex is presented,including the ongoing efforts and plans for technological research and develop-ment,as well as the required infrastructure.The STCF project aims to secure support from the Chinese central government for its construction during the 15th Five-Year Plan(2026-2030). 展开更多
- 关键词 Third-generation electron-positron collider Super high-luminosity Tau-charm physics Crab-waist collision scheme Touschek lifetime
- Color-tunable multi-stimuli-responsive luminescent system based on diarylethene and photoacid 认领 引用 被引量：1
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- 作者 Hong-Guang Fu Xuan Wu +3 位作者 Hui-Juan Wang Fanjun Zhang Yong Chen Jing Xu 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第8期326-330,共5页
- The development of multi-stimuli-responsive luminescent system to address emerging demands is essential in anti-counterfeiting field.Herein,a photoswitchable system was reported,which was constructed from photoacid su... The development of multi-stimuli-responsive luminescent system to address emerging demands is essential in anti-counterfeiting field.Herein,a photoswitchable system was reported,which was constructed from photoacid sulfonato-merocyanine(MEH-D)serving as H+donor and diarylethene derivative(DAEA1)as acceptor.After capturing 2 equiv.HCl,the obtained fluorescent molecule DAE-A1-H showed solvatochromic property.Further on,benefiting from that MEH-D released protons and became a ring-closed isomer spiropyran(SP-D)under 440 nm irradiation,DAE-A1 was protonated,turning on fluorescence effect was realized in DAE-A1/MEH-D.In dark,a photo-activated reversible process was realized with SPD changed to MEH-D in situ system.In addition,the OF-DAE-A1-H/SP-D could efficiently and reversibly switch on/off its luminescence upon irradiation by UV–vis light.Significantly,the multi-stimuli-responsive system was successfully applied in logic gate and fluorescence ink,making it an efficient strategy for information encryption and decryption with higher security requirements. 展开更多
- 关键词 Multi-stimuli-responsive luminescent system Diarylethene photoacid Logic gate Anti-counterfeiting
- FSMMTD: A Feature Subset-Based Malicious Traffic Detection Method 认领 引用 被引量：1
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- 作者 Xuan Wu Yafei Song +2 位作者 Xiaodan Wang Peng Wang Qian Xiang 《Computers, Materials & Continua》 SCIE EI 2025年第7期1279-1305,共27页
- With the growth of the Internet of Things(IoT)comes a flood of malicious traffic in the IoT,intensifying the challenges of network security.Traditional models operate with independent layers,limiting their effectivene... With the growth of the Internet of Things(IoT)comes a flood of malicious traffic in the IoT,intensifying the challenges of network security.Traditional models operate with independent layers,limiting their effectiveness in addressing these challenges.To address this issue,we propose a cross-layer cooperative Feature Subset-Based Malicious Traffic Detection(FSMMTD)model for detecting malicious traffic.Our approach begins by applying an enhanced random forest method to adaptively filter and retain highly discriminative first-layer features.These processed features are then input into an improved state-space model that integrates the strengths of recurrent neural networks(RNNs)and transformers,enabling superior processing of complex patterns and global information.This integration allows the FSMMTD model to enhance its capability in identifying intricate data relationships and capturing comprehensive contextual insights.The FSMMTD model monitors IoT data flows in real-time,efficiently detecting anomalies and enabling rapid response to potential intrusions.We validate our approach using the publicly available ToN_IoT dataset for IoT traffic analysis.Experimental results demonstrate that our method achieves superior performance with an accuracy of 98.37%,precision of 96.28%,recall of 95.36%,and F1-score of 96.79%.These metrics indicate that the FSMMTD model outperforms existing methods in detecting malicious traffic,showcasing its effectiveness and reliability in enhancing IoT network security. 展开更多
- 关键词 Network security malicious traffic detection internet of things
- Developing the occupational skills qualifications framework for floral designer education and training in the floristry industry 认领 引用 被引量：1
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- 作者 Xuan Wu William J.McKinley Charles R.Hall 《Technology in Horticulture》 2025年第1期238-245,共8页
- Retail florists,integral to the floristry industry,are experiencing workforce challenges due to an aging population and a shortage of well-trained entrants.New talent recruitment and retention are critical to the sust... Retail florists,integral to the floristry industry,are experiencing workforce challenges due to an aging population and a shortage of well-trained entrants.New talent recruitment and retention are critical to the sustainability and prosperity of the profession and its associated industries.Occupational skill standards assist in identifying competencies for success in the profession.This research established skills profiles of floral designers in the U.S.by examining occupational skills standards from the United Kingdom(U.K.),Finland,India,and Singapore.The framework outlines competencies needed for progression from entry-level to master-level designers,detailing roles,tasks,knowledge,and abilities to address challenges,and autonomy of work at each level.Ten competency categories were identified across all levels.This framework can serve as a foundation for career development strategies,elevating professionalism and boosting workforce competitiveness.Through adoption,along with other recommended strategies to address labor shortage issues,the floristry industry can enhance its ability to attract,train,and retain skilled designers,ensuring long-term growth and sustainability. 展开更多
- 关键词 occupational skills standards skill standards workforce challenges skills profiles floral design floral designers qualifications framework identifying competencies
- Evaluating the practicality of the educational and occupational frameworks for floral designer education and training in the floristry industry 认领 引用
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- 作者 Xuan Wu William J.McKinley Charles R.Hall 《Technology in Horticulture》 2025年第1期195-200,共6页
- The floristry industry faces enduring challenges,including an aging workforce,workforce shortages,and competition from mass-produced floral products.These challenges hinder the sector's growth and competitiveness.... The floristry industry faces enduring challenges,including an aging workforce,workforce shortages,and competition from mass-produced floral products.These challenges hinder the sector's growth and competitiveness.To address these issues,the Texas A&M University floral design team developed two comprehensive frameworks:an Educational and Career Pathways framework and an Occupational Skills Qualifications framework.These frameworks aim to support floral designer training and advancement.This study evaluates the practicality of these frameworks through feedback from industry professionals on the relevance of ten core competencies critical to various career levels in floral design.Survey findings indicate that 80%of respondents are inclined to adopt the educational framework,and 88%expressed interest in the occupational framework,recognizing their potential to standardize skills,enhance career development,and elevate professional standards.The frameworks show promise as tools to attract new talent and support sustained industry growth,positioning them as essential resources for strengthening the floristry industry. 展开更多
- 关键词 floral design workforce shortages occupational skills qualifications frameworkthese professional standards occupational skills qualifications educational career pathways framework floral designer educational framework
- Back-n white neutron source at CSNS and its applications 认领 引用 被引量：52
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- 作者 Jing-Yu Tang Qi An +73 位作者 Jiang-Bo Bai Jie Bao Yu Bao Ping Cao Hao-Lei Chen Qi-Ping Chen Yong-Hao Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Xing-Yan Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Yi-Wei Yang Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu The CSNS Back-n Collaboration 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2021年第1期95-104,共10页
- Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n w... Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n white neutron source),which was completed in March 2018.The Back-n neutron beam is very intense,at approximately 29107 n/cm2/s at 55 m from the target,and has a nominal proton beam with a power of 100 kW in the CSNS-I phase and a kinetic energy of 1.6 GeV and a thick tungsten target in multiple slices with modest moderation from the cooling water through the slices.In addition,the excellent energy spectrum spanning from 0.5 eV to 200 MeV,and a good time resolution related tothe time-of-flight measurements make it a typical white neutron source for nuclear data measurements;its overall performance is among that of the best white neutron sources in the world.Equipped with advanced spectrometers,detectors,and application utilities,the Back-n facility can serve wide applications,with a focus on neutron-induced cross-sectional measurements.This article presents an overview of the neutron beam characteristics,the experimental setups,and the ongoing applications at Backn. 展开更多
- 关键词 White neutron source Nuclear data measurements Experimental setups Neutron applications
- Measurement of the neutron total cross section of carbon at the Back-n white neutron beam of CSNS 认领 引用 被引量：16
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- 作者 Xing-Yan Liu Yi-Wei Yang +79 位作者 Rong Liu Jie Wen Zhong-Wei Wen Zi-Jie Han Zhi-Zhou Ren Qi An Huai-Yong Bai Jie Bao Ping Cao Qi-Ping Chen Yong-Hao Chen Pin-Jing Cheng Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Min-Hao Gu Feng-Qin Guo Chang-Cai Han Guo-Zhu He Yong-Cheng He Yue-Feng He Han-Xiong Huang Wei-Ling Huang Xi-Ru Huang Xiao-Lu Ji Xu-Yang Ji Hao-Yu Jiang Wei Jiang Han-Tao Jing Ling Kang Ming-Tao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Shu-Bin Liu Guang-Yuan Luan Ying-Lin Ma Chang-Jun Ning Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Hong Sun Xiao-Yang Sun Zhi-Jia Sun Zhi-Xin Tan Hong-Qing Tang Jing-Yu Tang Peng-Cheng Wang Qi Wang Tao-Feng Wang Yan-Feng Wang Zhao-Hui Wang Zheng Wang Qing-Biao Wu Xiao-Guang Wu Xuan Wu Li-Kun Xie Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Jing Zhang Lin-Hao Zhang Li-Ying Zhang Qing-Min Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Ying-Tan Zhao Liang Zhou Zu-Ying Zhou Dan-Yang Zhu Ke-Jun Zhu Peng Zhu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2019年第9期73-82,共10页
- To verify the performance of the neutron total cross-sectional spectrometer,the neutron total cross section of carbon is initially measured in the energy range of 1 eV to 20 MeV using the time-of-flight method.The mea... To verify the performance of the neutron total cross-sectional spectrometer,the neutron total cross section of carbon is initially measured in the energy range of 1 eV to 20 MeV using the time-of-flight method.The measurement is performed at the Back-n white neutron source with a 76-m time-of-flight path using the China Spallation Neutron Source.A multilayer fast fission chamber with 235U and 238U is employed as the neutron detector.The diameter and thickness of the natural graphite sample are 70 mm and 40 mm,respectively.Signal waveforms are collected using a data acquisition system.Off-line data processing was used to obtain the neutron time-of-flight spectra and transmissions.The uncertainty of the counting statistics is generally approximately 3%for each bin in the energy range of 1–20 MeV.It is determined that the results for the neutron total cross section of carbon obtained using^235U cells are in good agreement with the results obtained using 238U cells within limits of statistical uncertainty.Moreover,the measured total cross sections show good agreement with the broadening evaluated data. 展开更多
- 关键词 CSNS Back-n white neutron source NTOX Neutron total cross section Carbon Multilayer fast fission chamber
- A Wheeled Wall-Climbing Robot with Bio-Inspired Spine Mechanisms 认领 引用 被引量：25
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- 作者 Yanwei Liu Shaoming Sun +1 位作者 Xuan Wu Tao Mei 《Journal of Bionic Engineering》 SCIE EI CSCD 2015年第1期17-28,共12页
- This paper presents a wheeled wall-climbing robot with the ability to climb concrete, brick walls using circular arrays of miniature spines located around the wheel. The robot consists of two driving wheels and a flex... This paper presents a wheeled wall-climbing robot with the ability to climb concrete, brick walls using circular arrays of miniature spines located around the wheel. The robot consists of two driving wheels and a flexible tail, just like letter “T”, so it is called Tbot. The simple and effective structure of Tbot enables it to be steerable and to transition from horizontal to vertical surfaces rapidly and stably. Inspired by the structure and mechanics of the tarsal chain in the Serica orientalis Motschulsky, a compliant spine mechanism was developed. With the bio-inspired compliant spine mechanism, the climbing performance of Tbot was improved. It could climb on 100° （10° past vertical） brick walls at a speed of 10 cm·s^-1. A mechanical model is also presented to analyze the forces acting on spine during a climbing cycle as well as load share between multi-spines. The simu- lation and experiment results show that the mechanical model is suitable and useful in the optimum design of Tbot. 展开更多
- 关键词 biologically-inspired robots climbing robots compliant spine mechanisms mechanical model wheeled robots
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- Measurement of the 232Th(n,f)cross section in the 1-200 MeV range at the CSNS Back-n 认领 引用 被引量：8
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- 作者 Zhi-Zhou Ren Yi-Wei Yang +77 位作者 Yong-Hao Chen Rong Liu Bang-Jiao Ye Jie Wen Hai-Rui Guo Zi-Jie Han Qi-Ping Chen Zhong-Wei Wen Wei-Li Sun Han Yi Xing-Yan Liu Tao Ye Jiang-Bo Bai Qi An Jie Bao Yu Bao Ping Cao Hao-Lei Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Shu-Bin Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Jing-Yu Tang Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第8期142-153,共12页
- The 232Th(n,f)cross section is very important in basic nuclear physics and applications based on the Th/U fuel cycle.Using the time-of-flight method and a multi-cell fast-fission ionization chamber,a novel measurem... The 232Th(n,f)cross section is very important in basic nuclear physics and applications based on the Th/U fuel cycle.Using the time-of-flight method and a multi-cell fast-fission ionization chamber,a novel measurement of the232Th(n,f)cross sec-tion relative to235U in the 1–200 MeV range was performed at the China Spallation Neutron Source Back-n white neutron source(Back-n).The fission event-neutron energy spectra of232Th and235U fission cells were measured in the single-bunch mode.Corrected 232Th/235U fission cross-sectional ratios were obtained,and the measurement uncertainties were 2.5–3.7%for energies in the 2–20 MeV range and 3.6–6.2%for energies in the 20–200 MeV range.The232Th(n,f)cross section was obtained by introducing the standard cross section of235U(n,f).The results were compared with those of previous theoreti-cal calculations,measurements,and evaluations.The measured 232Th fission cross section agreed with the main evaluation results in terms of the experimental uncertainty,and 232Th fission resonances were observed in the 1–3 MeV range.The present results provide232Th(n,f)cross-sectional data for the evaluation and design of Th/U cycle nuclear systems. 展开更多
- 关键词 232Th(n f)cross section Fast-fission ionization chamber Back-n white neutron source
- From static to dynamic:live observation of the support system after ischemic stroke by two photon-excited fluorescence laser-scanning microscopy 认领 引用 被引量：5
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- 作者 Xuan Wu Jia-Rui Li +3 位作者 Yu Fu Dan-Yang Chen Hao Nie Zhou-Ping Tang 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第10期2093-2107,共15页
- Ischemic stroke is one of the most common causes of mortality and disability worldwide.However,treatment efficacy and the progress of research remain unsatisfactory.As the critical support system and essential compone... Ischemic stroke is one of the most common causes of mortality and disability worldwide.However,treatment efficacy and the progress of research remain unsatisfactory.As the critical support system and essential components in neurovascular units,glial cells and blood vessels(including the bloodbrain barrier)together maintain an optimal microenvironment for neuronal function.They provide nutrients,regulate neuronal excitability,and prevent harmful substances from entering brain tissue.The highly dynamic networks of this support system play an essential role in ischemic stroke through processes including brain homeostasis,supporting neuronal function,and reacting to injuries.However,most studies have focused on postmortem animals,which inevitably lack critical information about the dynamic changes that occur after ischemic stroke.Therefore,a high-precision technique for research in living animals is urgently needed.Two-photon fluorescence laser-scanning microscopy is a powerful imaging technique that can facilitate live imaging at high spatiotemporal resolutions.Twophoton fluorescence laser-scanning microscopy can provide images of the whole-cortex vascular 3D structure,information on multicellular component interactions,and provide images of structure and function in the cranial window.This technique shifts the existing research paradigm from static to dynamic,from flat to stereoscopic,and from single-cell function to multicellular intercommunication,thus providing direct and reliable evidence to identify the pathophysiological mechanisms following ischemic stroke in an intact brain.In this review,we discuss exciting findings from research on the support system after ischemic stroke using two-photon fluorescence laser-scanning microscopy,highlighting the importance of dynamic observations of cellular behavior and interactions in the networks of the brain’s support systems.We show the excellent application prospects and advantages of two-photon fluorescence laser-scanning microscopy and predict future research developments and directions in the study of ischemic stroke. 展开更多
- 关键词 astrocytes blood-brain barrier calcium signaling glymphatic system ischemic stroke microglia network remodel two-photon fluorescence laser-scanning microscopy vessels
- A discussion on evaluation criteria for crevice corrosion of various stainless steels 认领 引用 被引量：6
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- 作者 Xuan Wu Yuanyuan Liu +3 位作者 Yangting Sun Nianwei Dai Jin Li Yiming Jiang 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2021年第5期29-37,共9页
- In this study,crevice corrosion performances of a newly developed LDSS 2002 and three commercial stainless steels(AISI 304,AISI 316L and DSS 2205)were investigated and discussed.Crevice repassivation potential(ER,CREV... In this study,crevice corrosion performances of a newly developed LDSS 2002 and three commercial stainless steels(AISI 304,AISI 316L and DSS 2205)were investigated and discussed.Crevice repassivation potential(ER,CREV),which was measured by the potentiodynamic-galvanostatic-potentiodynamic(PDGS-PD)test,was applicable to crevice corrosion evaluation of 304 and 316 L stainless steels.However,much lower(ER,CREV values were obtained for DSS 2205 and LDSS 2002.These abnormal(ER,CREV values for duplex stainless steels may be related to the selective attack of the less corrosion-resistant phase,the lower corrosion potential in the crevice-like solution,and more crevice corrosion sites in the PD-GS-PD test.A critical chloride concentration of crevice corrosion(CCCCREV)measurement was introduced for crevice corrosion evaluation of various stainless steels.The derived CCCCREVwas proved to be a valid criterion for crevice corrosion evaluation of both the austenitic and duplex stainless steels.An order of crevice corrosion resistance of AISI 304≈LDSS 2002<AISI 316 L<DSS 2205 was suggested,which agreed well with the orders of pitting resistance equivalent number and critical crevice index of the less corrosion-resistant phase in each material. 展开更多
- 关键词 Stainless steel Crevice corrosion Crevice repassivation potential Critical chloride concentration
- Petrogenesis of the Late Triassic shoshonitic Shadegai pluton from the northern North China Craton: Implications for crust-mantle interaction and post-collisional extension 认领 引用 被引量：3
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- 作者 Liqiong Jia Liang Wang +2 位作者 Genhou Wang Shibin Lei Xuan Wu 《Geoscience Frontiers》 SCIE CAS CSCD 2019年第2期595-610,共16页
- Latest Permian to Triassic plutons are widespread in the northern North China Craton(NCC); most of them show calc-alkaline, high-K calc-alkaline, or alkaline geochemical features. The Shadegai pluton in the Wulashan a... Latest Permian to Triassic plutons are widespread in the northern North China Craton(NCC); most of them show calc-alkaline, high-K calc-alkaline, or alkaline geochemical features. The Shadegai pluton in the Wulashan area has shoshonitic affinity and I-type character, and is composed of syenogranites containing abundant mafic microgranular enclaves(MMEs). LA-MC-ICP-MS U-Pb data yield weighted mean 206 Pb/238 U ages of 222 ± 1 Ma and 221 ± 1 Ma for the syenogranites and MMEs, respectively, suggesting their coeval formation during the Late Triassic. The syenogranites have high SiO_2(70.42-72.30 wt%),K_2O(4.58-5.22 wt.%) and Na_2O(4.19-4.43 wt.%) contents but lower concentrations of P_2O_5(0.073-0.096 wt.%) and TiO_2(0.27-0.37 wt.%), and are categorized as I-type granites, rather than A-type granites, as previously thought. These syenogranites exhibit lower(87Sr/86Sr)i ratios(0.70532-0.70547) and strongly negative whole-rock εNd(t) values(-12.54 to-11.86) and zircon εHf(t) values(-17.81 to-10.77),as well as old Nd(1962-2017 Ma) and Hf(2023-2092 Ma) model ages, indicating that they were derived from the lower crust.Field and petrological observations reveal that the MMEs within the pluton probably represent magmatic globules commingled with their host magmas. Geochemically, these MMEs have low SiO_2(53.46-55.91 wt.%)but high FeOt(7.27-8.79 wt.%) contents. They are enriched in light rare earth elements(LREEs) and large ion lithophile elements(LILEs), and are depleted in heavy rare earth elements(HREEs) and high field strength elements(HFSEs). They have whole-rock(87Sr/86Sr)i ratios varying from 0.70551 to 0.70564, εNd(t) values of -10.63 to -9.82, and zircon εHf(t) values of -9.89 to 0.19. Their geochemical and isotopic features indicate that they were derived from the subcontinental lithospheric mantle mainly metasomatized by slab-derived fluids, with minor involvement of melts generated from the ascending asthenospheric mantle. Petrology integrated with elemental and isotopic geochemistry suggest that the Shadegai pluton was produced by crust-mantle interactions, i.e., partial melting of the lower continental crust induced by underplating of mantle-derived mafic magmas(including the subcontinental lithospheric mantle and asthenospheric mantle), and subsequent mixing of the mantle-and crust-derived magmas. In combination with existing geological data, it is inferred that the Shadegai pluton formed in a post-collisional extensional regime related to lithospheric delamination following the collision between the NCC and Mongolia arc terranes. 展开更多
- 关键词 Magma mixing Crust-mantle interaction Lithospheric delamination Post-collision North China Craton
- In-beam gamma rays of CSNS Back-n characterized by black resonance filter 认领 引用 被引量：5
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- 作者 Jin-Cheng Wang Jie Ren +68 位作者 Wei Jiang Xi-Chao Ruan Ying-Yi Liu Hao-Lan Yang Kuo-Zhi Xu Xin-Yi Pan Qi Sun Jie Bao Han-Xiong Huang Hao-Fan Bai Jiang-Bo Bai Ping Cao Qi-Ping Chen Yong-Hao Chen Wen-Hao Duan An-Chuan Fan Rui-Rui Fan Chang-Qing Feng Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Zhi-Jie Jiang Ling Kang Chang-Lin Lan Bo Li Feng Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Yi-Na Liu Guang-Yuan Luan Chang-Jun Ning Yi-Jia Qiu Wen-Kai Ren Zhi-Zhou Ren Zhao-Hui Song Kang Sun Zhi-Xin Tan Jing-Yu Tang Sheng-Da Tang Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Ze-Peng Wu Cong Xia Li-Kun Xie Han Yi Tao Yu Yong-Ji Yu Guo-Hui Zhang Hang-Chang Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Mao-Yuan Zhao Zhi-Hao Zhou Ke-Jun Zhu Chong Zou 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第10期149-160,共12页
- The back-streaming white-neutron beamline(Back-n)of the China Spallation Neutron Source is an essential neutronresearch platform built for the study of nuclear data,neutron physics,and neutron applications.Many types ... The back-streaming white-neutron beamline(Back-n)of the China Spallation Neutron Source is an essential neutronresearch platform built for the study of nuclear data,neutron physics,and neutron applications.Many types of cross-sectional neutron-reaction measurements have been performed at Back-n since early 2018.These measurements have shown that a significant number of gamma rays can be transmitted to the experimental stations of Back-n along with the neutron beam.These gamma rays,commonly referred to as in-beam gamma rays,can induce a non-negligible experimental background in neutron-reaction measurements.Studying the characteristics of in-beam gamma rays is important for understanding the experimental background.However,measuring in-beam gamma rays is challenging because most gamma-ray detectors are sensitive to neutrons;thus,discriminating between neutron-induced signals and those from in-beam gamma rays is difficult.In this study,we propose the use of the black resonance filter method and a CeBr3 scintillation detector to measure the characteristics of the in-beam gamma rays of Back-n.Four types of black resonance filters,181Ta,59Co,natAg,andnatCd,were used in this measurement.The time-of-flight(TOF)technique was used to select the detector signals remaining in the absorption region of the TOF spectra,which were mainly induced by in-beam gamma rays.The energy distribution and flux of the in-beam gamma rays of Back-n were determined by analyzing the deposited energy spectra of the CeBr3 scintillation detector and using Monte Carlo simulations.Based on the results of this study,the background contributions from in-beam gamma rays in neutron-reaction measurements at Back-n can be reasonably evaluated,which is beneficial for enhancing both the experimental methodology and data analysis. 展开更多
- 关键词 In-beam gamma rays Back-n CeBr3scintillator Black filter resonance technique
- Electropolymerization of cobalt porphyrins and corroles for the oxygen evolution reaction 认领 引用 被引量：4
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- 作者 Qingxin Zhang Yabo Wang +8 位作者 Yanzhi Wang Shujiao Yang Xuan Wu Bin Lv Ni Wang Yimei Gao Xiaoran Xu Haitao Lei Rui Cao 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第12期3807-3810,共4页
- Developing large-scale electrocatalysts using molecular complexes for the oxygen evolution reaction(OER)is of great importance. Herein, four cobalt porphyrins and corroles are deposited on electrode substrates using a... Developing large-scale electrocatalysts using molecular complexes for the oxygen evolution reaction(OER)is of great importance. Herein, four cobalt porphyrins and corroles are deposited on electrode substrates using a simple and fast electropolymerization method. Our results showed that Co-1-P@CC, formed by electropolymerizing Co tetrakis(p-N-pyrrolylphenyl)porphyrin(Co-1-P) on carbon cloth(CC), is the most active OER catalyst in the examined Co porphyrins and corroles in alkaline aqueous solutions by displaying an onset overpotential of 380 m V. Long-term electrolysis tests confirmed the stability of these electropolymerized films by functioning as OER electrocatalysts. 展开更多
- 关键词 Cobalt corroles Cobalt porphyrins Electropolymerization Molecular electrocatalysis Oxygen evolution
- Boosting extraction of Pb in contaminated soil via interfacial solar evaporation of multifunctional sponge 认领 引用 被引量：3
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- 作者 Pan Wu Xuan Wu +3 位作者 Yida Wang Jingyuan Zhao Haolan Xu Gary Owens 《Green Energy & Environment》 SCIE EI CAS CSCD 2023年第5期1459-1468,共10页
- Interfacial solar water evaporation is a reliable way to accelerate water evaporation and contaminant remediation.Embracing the recent advance in photothermal technology,a functional sponge was prepared by coating a s... Interfacial solar water evaporation is a reliable way to accelerate water evaporation and contaminant remediation.Embracing the recent advance in photothermal technology,a functional sponge was prepared by coating a sodium alginate(SA)impregnated sponge with a surface layer of reduced graphene oxide(rGO)to act as a photothermal conversion medium and then subsequently evaluated for its ability to enhance Pb extraction from contaminated soil driven by interfacial solar evaporation.The SA loaded sponge had a Pb adsorption capacity of 107.4 mg g-1.Coating the top surface of the SA sponge with rGO increased water evaporation performance to 1.81 kg m-2h-1in soil media under one sun illumination and with a wind velocity of 2 m s-1.Over 12 continuous days of indoor evaporation testing,the Pb extraction efficiency was increased by 22.0%under 1 sun illumination relative to that observed without illumination.Subsequently,Pb extraction was further improved by 48.9%under outdoor evaporation conditions compared to indoor conditions.Overall,this initial work shows the significant potential of interfacial solar evaporation technologies for Pb contaminated soil remediation,which should also be applicable to a variety of other environmental contaminants. 展开更多
- 关键词 Photothermal materials Interfacial solar evaporation Reduced graphene oxide Pb extraction Soil remediation
- 题名Recombinant tissue plasminogen activator protects neurons after intracerebral hemorrhage through activating the PI3K/AKT/mTOR pathway 认领 引用 被引量：1
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- 作者 Jie Jing Shiling Chen Xuan Wu Jingfei Yang Xia Liu Jiahui Wang Jingyi Wang Yunjie Li Ping Zhang Zhouping Tang
- 机构 Department of Neurology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Province Department of Neurology,Qilu Hospital of Shandong University,Shandong Province
- 出处 《Neural Regeneration Research》 SCIE CAS CSCD 2026年第4期1574-1585,共12页
- 基金 supported by the National Natural Science Foundation of China,Nos.92148206,82071330(both to ZT) a grant from the Major Program of Hubei Province,No.2023BAA005(to ZT) +1 种基金 a grant from the Key Research and Discovery Program of Hubei Province,No.2021BCA109(to ZT) the Research Foundation of Tongji Hospital,No.2022B37(to PZ)。
- 摘要 Recombinant tissue plasminogen activator is commonly used for hematoma evacuation in minimally invasive surgery following intracerebral hemorrhage.However,during minimally invasive surgery,recombinant tissue plasminogen activator may come into contact with brain tissue.Therefore,a thorough assessment of its safety is required.In this study,we established a mouse model of intracerebral hemorrhage induced by type VII collagenase.We observed that the administration of recombinant tissue plasminogen activator without hematoma aspiration significantly improved the neurological function of mice with intracerebral hemorrhage,reduced pathological damage,and lowered the levels of apoptosis and autophagy in the tissue surrounding the hematoma.In an in vitro model of intracerebral hemorrhage using primary cortical neurons induced by hemin,the administration of recombinant tissue plasminogen activator suppressed neuronal apoptosis,autophagy,and endoplasmic reticulum stress.Transcriptome sequencing analysis revealed that recombinant tissue plasminogen activator upregulated the phosphoinositide 3-kinase/RAC-alpha serinehreonine-protein kinase/mammalian target of rapamycin pathway in neurons.Moreover,the phosphoinositide 3-kinase inhibitor LY294002 abrogated the neuroprotective effects of recombinant tissue plasminogen activator in inhibiting excessive apoptosis,autophagy,and endoplasmic reticulum stress.Furthermore,to specify the domain of recombinant tissue plasminogen activator responsible for its neuroprotective effects,various inhibitors were used to target distinct domains.It has been revealed that the epidermal growth factor receptor inhibitor AG-1478 reversed the effect of recombinant tissue plasminogen activator on the phosphoinositide 3-kinase/RAC-alpha serinehreonineprotein kinase/mammalian target of rapamycin pathway.These findings suggest that recombinant tissue plasminogen activator exerts a direct neuroprotective effect on neurons following intracerebral hemorrhage,possibly through activation of the phosphoinositide 3-kinase/RAC-alpha serinehreonine-protein kinase/mammalian target of rapamycin pathway.
- 关键词 apoptosis autophagy endoplasmic reticulum stress epidermal growth factor intracerebral hemorrhage mammalian target of rapamycin minimally invasive surgery phosphoinositide 3-kinase RAC-alpha serinehreonine-protein kinase recombinant tissue plasminogen activator
- 分类号 R743.34 [医药卫生—神经病学与精神病学]
- 题名Cucurbit[7]uril-confined cascade assembly of cyclodextrin phosphor derivative achieving multicolor delayed luminescence for information encryption 认领 引用
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- 作者 Jie Niu Xuan Wu Jie Yu Zhuo Lei Ying-Ming Zhang Li-Hua Wang Yu Liu
- 机构 College of Chemistry,State Key Laboratory of Elemento-Organic Chemistry,Nankai University School of Chemistry and Chemical Engineering,Yangzhou University,Yangzhou
- 出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第5期332-338,共7页
- 基金 financially supported by the National Natural Science Foundation of China(Nos.22171148,22371148,22131008,22101280,and 22201142) the Natural Science Foundation of Tianjin(No.21JCZDJC00310) +1 种基金 Haihe Laboratory of Sustainable Chemical Transformation the Fundamental Research Funds for the Central Universities(Nankai University)。
- 摘要 Macrocyclic cascade supramolecular assembly could significantly enhance the fluorescence/phosphorescence resonance energy transfer(F/PRET)efficiency through macrocyclic and spatial dual confinement effect.Herein,we reported a cascade supramolecular assembly containing6-bromoisoquinolinium-modified permethylated cyclodextrin(BQ-PCD),cucurbit[7]uril(CB[7]),and tetra(4-sulfonatophenyl)porphyrin(TPPS),in which the enhanced PRET from 6-bromoisoquinolinium(BQ)to TPPS could be achieved through the dual macrocyclic confinement for multicolor delayed luminescence and information encryption.In TPPS⊂BQ-PCD⊂CB[7],pure organic room temperature phosphorescence of BQ-PCD at 530 nm is induced by CB[7]macrocyclic confinement,which further transferred to TPPS via spatial confinement,achieving delayed fluorescence at 645 and 715 nm with high PRET efficiency and quantum yield(17.9%).Meanwhile,reversible TPPS concentration-dependent multicolor luminescence was achieved in presence of competitive guest(methionine peptide),followed by porphyrin-photosensitization process,being applied in information encryption.This research presents a facile strategy for efficient PRET through macrocyclic cascade confinement assembly.
- 关键词 Macrocyclic confinement effect Cascade assembly Phosphorescence resonance energy transfer Delayed multicolor luminescence Guest competitive binding Information encryption
- 分类号 O641.3 [理学—物理化学] TP309.7 [理学—化学]
- 题名Ultrasound/magnetic field dual-responsive Fe3O4/glucose oxidase catalytic microbubbles for enhanced bacterial biofilm elimination 认领 引用
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- 作者 Chi Zhang Dou Wang Liang Lu Feng-Jiao Xu Fan-Sen Xu Xuan Wu Xiao-Xiao Xu Xiao Li Li-Hui Yuwen
- 机构 Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology,Institute of Advanced Materials（IAM）,Nanjing University of Posts and Telecommunications School of Electronic Information,Nanjing Vocational College of Information Technology
- 出处 《Biomedical Engineering Communications》 CAS 2026年第1期4-12,共9页
- 基金 supported by the National Natural Science Foundation of China(22375101) the Natural Science of Colleges and Universities in Jiangsu Province(24KJB430027).
- 摘要 Background:The bacterial biofilm poses a significant challenge to traditional antibiotic therapy.There is a great need to develop novel antibiofilm agents combined with biofilm disrupting and bacteria-killing without the dependence of antibiotic.Methods:Herein,we prepared ultrasound/magnetic field-responsive ferroferric oxide nanoparticles(Fe3O4)/glucose oxidase microbubbles(FGMB)to form a cascade catalytic system for effective removing methicillin-resistant Staphylococcus aureus biofilms.FGMB were prepared through interfacial self-assembly of Fe3O4 nanoparticles(NPs)and glucose oxidase(GOx)at the gas-liquid interface stabilized by surfactants.Under ultrasound/magnetic field stimulation,FGMB disrupted biofilm architecture through microbubble collapse-induced microjets and magnetically driven displacement.Simultaneously,ultrasound-triggered rupture of FGMB released GOx and Fe3O4 NPs.Glucose can be oxidized by GOx to generate gluconic acid and hydrogen peroxide which was subsequently catalyzed into hydroxyl radicals by Fe3O4 NPs,enabling chemical eradication of biofilm-embedded bacteria.Results:Optical microscopy images demonstrated that FGMB have spherical structure with average size of approximately 17μm.FGMB showed a 65.4%decrease in methicillin-resistant Staphylococcus aureus biofilm biomass and 1.1 log bacterial inactivation efficiency(91.2%),suggesting effective biofilm elimination.In vitro experimental results also indicate that FGMB have good biocompatibility.Conclusion:This antibiofilm strategy integrated dual modes of physical biofilm disruption with chemical bacteria-killing shows great potential as a versatile,non-resistant strategy for bacterial biofilm elimination.
- 关键词 bacterial biofilm ultrasound magnetic field catalytic microbubbles mechanical disruption chemical degradation
- 分类号 R318.08 [医药卫生—生物医学工程]
- 题名Cell polarization in ischemic stroke: molecular mechanisms and advances 认领 引用 被引量：18
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- 作者 Yuanwei Li Xiaoxiao Xu Xuan Wu Jiarui Li Shiling Chen Danyang Chen Gaigai Li Zhouping Tang
- 机构 Department of Neurology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Province
- 出处 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第3期632-645,共14页
- 基金 supported by the National Natural Science Foundation of China, Nos.82201474 (to GL), 82071330 (to ZT), and 92148206 (to ZT) Key Research and Discovery Program of Hubei Province, No.2021BCA109 (to ZT)。
- 摘要 Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.
- 关键词 astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke
- 分类号 R743.3 [医药卫生—神经病学与精神病学]
- 题名pH-responsive chiral supramolecular cysteine-Zn2+-indocyanine green assemblies for triple-level chirality-specific anti-tumor efficacy 认领 引用 被引量：1
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- 作者 Qianyun Ye Yuanyuan Liang Yuhe Yuan Xiaohuan Sun Liqi Zhu Xuan Wu Jie Han Rong Guo
- 机构 School of Chemistry and Chemical Engineering,Yangzhou University College of Veterinary Medicine,Yangzhou University
- 出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第5期289-296,共8页
- 基金 supported by the National Natural Science Foundation of China(Nos.22002138,22372144,22272146,21922202) the Chinese Postdoctoral Science Foundation(No.2021M692714) the Priority Academic Program Development of Jiangsu Higher Education Institutions.
- 摘要 Chirality,ubiquitous in living matter,plays vital roles in a series of physiological processes.The clarification of the multiple functions of chirality in bioapplications may provide innovative methodologies for engineering anti-tumor agents.Nevertheless,the related research has been rarely explored.In this study,the chiral supramolecular l/d-cysteine(Cys)-Zn2+-indocyanine green(ICG)nanoparticles were constructed through the coordination interaction between l/d-Cys and Zn2+,followed by the encapsulation of ICG.Experimental findings revealed that the d-Cys-Zn2+-ICG exhibited 17.31 times higher binding affinity toward phospholipid-composed liposomes compared to l-Cys-Zn2+-ICG.Furthermore,driven by chiralityspecific interaction,a 2.07 folds greater cellular internalization of d-Cys-Zn2+-ICG than l-Cys-Zn2+-ICG was demonstrated.Additionally,the triple-level chirality-dependent photothermal,photodynamic and Zn2+releasing anti-tumor effects of l/d Cys-Zn2+-ICG in vitro were verified.As a result,the d-formed nanoparticles achieved 1.93 times higher anti-tumor efficiency than the l-formed ones.The triple-level chirality-mediated anti-tumor effect highlighted in this study underscores the enormous potential of chirality in biomedicine and holds substantial significance in improving cancer therapeutic efficacy.
- 关键词 Chirality pH-responsiveness Photothermal therapy Photodynamic therapy Zn2+release
- 分类号 R730.5 [医药卫生—肿瘤] TB383 [医药卫生—临床医学]
- 题名Conceptual design report of the Super Tau-Charm Facility:the accelerator 认领 引用 被引量：1
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- 作者 Xiao-Cong Ai Liu-Pan An Shi-Zhong An Yu Bai Zheng-He Bai Olga Bakina Jian-Cong Bao Varvara Batozskaya Anastasios Belias Maria Enrica Biagini Li-Gong Bian Denis Bodrov Anton Bogomyagkov Manuela Boscolo Igor Boyko Ze-Xin Cao Serkant Cetin Marina Chadeeva Ming-Xuan Chang Qin Chang Dian-Yong Chen Fang-Zhou Chen Hai Chen Hua-Xing Chen Jin-Hui Chen Long Chen Long-Bin Chen Qi Chen Qu-Shan Chen Shao-Min Chen Wei Chen Ying Chen Zhi Chen Shan Cheng Si-Bo Cheng Tong-Guang Cheng Lian-Rong Dai Ling-Yun Dai Xin-Chen Dai Achim Denig Igor Denisenko Denis Derkach Heng-Tong Ding Ming-Hui Ding Xiao Ding Liao-Yuan Dong Yong Du Prokhor Egorov Kuan-Jun Fan Si-Yuan Fan Shuang-Shi Fang Zhu-Jun Fang Song Feng Xu Feng Hai-Bing Fu Jun Gao Yuan-Ning Gao Zi-Han Gao Cong Geng Li-Sheng Geng Hai-Liang Gong Jia-Ding Gong Li Gong Shao-Kun Gong Sergi Gonzàlez-Solís Bo-Xing Gou Duan Gu Hao Guo Jun Guo Teng-Jun Guo Xin-Heng Guo Yu-Hui Guo Yu-Ping Guo Zhi-Hui Guo Selcuk Haciomeroglu Eiad Hamwi Cheng-Dong Han Ting-Ting Han Xi-Qing Hao Chong-Chao He Ji-Bo He Tian-Long He Xiao-Gang He Masahito Hosaka Kai-Wen Hou Zhi-Long Hou Dong-Dong Hu Hai-Ming Hu Hao Hu Qi-Peng Hu Tong-Ning Hu Xiao-Cheng Hu Yu Hu Zhen Hu Da-Zhang Huang Fei Huang Guang-Shun Huang Liang-Sheng Huang Peng-Wei Huang Rui-Xuan Huang Xing-Tao Huang Xue-Lei Huang Zhi-Cheng Huang Wang Ji Peng-Kun Jia Sen Jia Ze-Kun Jia Hong-Ping Jiang Hou-Bing Jiang Jian-Bin Jiao Ming-Jie Jin Su-Ping Jin Yi Jin Daekyoung Kang Xian-Wei Kang Xiao-Lin Kang Leonid Kaptari Onur Bugra Kolcu Ivan Koop Evgeniy Kravchenko Yury Kudenko Meike Küßner Yong-Bin Leng Eugene Levichev Chao Li Chun-Yuan Li Chun-Hua Li Hai Tao Li Hai-Bo Li Hang-Zhou Li Heng-Ne Li Hong-Lei Li Hui-Jing Li Hui-Lin Li Jia-Rong Li Jin Li Lei Li Min Li Pei-Rong Li Pei-Lian Li Ren-Kai Li Sang-Ya Li Shu Li Teng Li Tian-You Li Wei-Wei Li Wen-Jun Li Xin Li Xin-Qiang Li Xin-Bai Li Xuan Li Xun-Feng Li Yan-Feng Li Ya-Xuan Li Ying Li Yu-Bo Li Jian Liang Xiao Liang Yu Liang Ze-Rui Liang Chuang-Xin Lin De-Xu Lin Ting Lin Yu-Gen Lin Chao Liu Chao Liu Chia-Wei Liu Gang-Wen Liu Hang Liu Hong-Bang Liu Jian-Bei Liu Jian-Dang Liu Lang-Tian Liu Liang-Chen Liu Ming-Yi Liu Shu-Bin Liu Tao Liu Tian-Bo Liu Xiang Liu Xiao-Yu Liu Xin Liu Xu-Yang Liu Yan-Rui Liu Yan-Lin Liu Yan-Wen Liu Yi Liu Yuan Liu Zhan-Wei Liu Zhao-Feng Liu Zhi-Qing Liu Zi-Rui Liu Zuo-Wei Liu Cai-Dian Lu Miao-Ran Lu Peng-Cheng Lu Yu Lu Qing Luo Tao Luo Tao Luo Xiao-Feng Luo Hui-Hui Lv Shuo-Tian Lyu Xiao-Rui Lyu Bo-Qiang Ma Cheng-Long Ma Shao-Hang Ma Teng Ma Wen-Bin Ma Yu Meng Meng-Xu Fan Xue-Ce Miao Mauro Migliorati Catia Milardi Taisiya Mineeva Yi-Hao Mo Hector Gisbert Mullor Elaf Musa Satoshi Nakamura Alexey Nefediev Yuan-Cun Nie Kazuhito Ohmi MPadmanath Pavel Pakhlov Jian Pang Emilie Passemar Guo-Xi Pei Hua Pei Hai-Ping Peng Liang Peng Rong-Gang Ping Bernard Pire Vindhyawasini Prasad Bin-Bin Qi Zhi-Jun Qi Yi Qian Cong-Feng Qiao Jia-Jia Qin Long-Yu Qin Qin Qin Xiao-Shuai Qin Fedor Ratnikov Craig Roberts Antonio Rodríguez-Sánchez Yury Rogovsky Platon Rogozhin Pablo Roig Man-Qi Ruan Jorge Segovia Feng-Lei Shang Lei Shang Jian-Feng Shangguan Ding-Yu Shao Ming Shao Zhuo-Xia Shao Cheng-Ping Shen Hong-Fei Shen Xiao-Min Shen Zhong-Tao Shen Cai-Tu Shi Jia-Lei Shi Rui-Xiang Shi Yu-Kun Shi Zong-Guo Si Luiz Vale Silva Mikhail Skamarokha Jun-Chao Su Guang-Bao Sun Jun-Feng Sun Kun Sun Li Sun Ming-Kai Sun Rui Sun Xu-Lei Sun Jing-Yu Tang Yin-Gao Tang Ze-Bo Tang Wei Tao Valery Telnov Jia-Xiu Teng Yuriy Tikhonov Cheng-Ying Tsai Timofey Uglov Vincenzo Vagnoni German Valencia Guan-Yue Wan An-Xin Wang Bin Wang Cheng-Zhe Wang En Wang Hong-Jin Wang Jia Wang Jie Wang Jun-Zhang Wang Lei Wang Lei Wang Lin Wang Qian Wang Qian Wang Sheng-Quan Wang Sheng-Yuan Wang Shi-Kang Wang Wei Wang Wei-Ping Wang Xiang-Peng Wang Xia-Yu Wang Xiong-Fei Wang Ya-Qian Wang Yu-Ming Wang Yu-Hao Wang Zeren Simon Wang Zhi Wang Zhi-Gang Wang Zhi-Yong Wang Zi-Yu Wang Zi-Rui Wang Bing-Feng Wei Shao-Qing Wei Shu-Yi Wei Xiao-Min Wei Ya-Jing Wei Ye-Long Wei Ulrich Wiedner Jia-Jun Wu Jun Wu Qun Wu Sang Wu Xin Wu Xing-Gang Wu Xuan Wu Yong-Cheng Wu Yu-Sheng Wu Lei Xia Zhi-Gang Xiao Chun-Jie Xie Kai-Bo Xie Zi-Yu Xiong Ji Xu Lai-Lin Xu Shu-Sheng Xu Xin Xu Yue Xu Liang Yan Wen-Biao Yan Xue-Qing Yan Chi Yang Hai-Jun Yang Hong-Tao Yang Jun Yang Peng-Hui Yang Shuai Yang Tao Yang Wei-Hua Yang Xing-Hua Yang Xue-Ting Yang Yue-Ling Yang Zhen-Wei Yang Zhong-Juan Yang De-Liang Yao Zao-Chen Ye Kai Yi Li Yi Li-Xin Yin Zheng-Yun You Chen Yu Ze Yu Jing Yuan You-Jin Yuan Nefedov Yury Yi-Feng Zeng Wang-Mei Zha Ai-Lin Zhang Ding-Yue Zhang Guang-Yi Zhang Guo-Heng Zhang Hai-Yan Zhang Hao-Ran Zhang Hong-Hao Zhang Hui-Bin Zhang Jia-Lian Zhang Jian-Rong Zhang Jian-Hui Zhang Jian-Yu Zhang Jie-Lei Zhang Lei Zhang Liang Zhang Ling-Hua Zhang Lin-Hao Zhang Ning Zhang Qiu-Yan Zhang Quan-Zheng Zhang Rui Zhang Rui-Yang Zhang Shao-Ru Zhang Sheng-Hui Zhang Shu-Lei Zhang Wen-Chao Zhang Xiao-Yang Zhang Xiao-Ming Zhang Xiao-Tao Zhang Xin Zhang Xin-Hui Zhang Yan-Xi Zhang Ya-Teng Zhang Yi-Hao Zhang Yi-Fei Zhang Yu Zhang Yu Zhang Yu-Mei Zhang Zhen-Yu Zhang Zhi-Qing Zhang Zhi-Cai Zhang Jia-Yao Zhao Ming-Gang Zhao Qiang Zhao Rui-Guang Zhao Yang-Cheng Zhao Ze-Xuan Zhao Zheng-Guo Zhao Alexey Zhemchugov Bo Zheng Jing-Xin Zheng Liang Zheng Ran Zheng Xu-Chang Zheng Yang-Heng Zheng Bin Zhong Dai-Cui Zhou De-Min Zhou Hang Zhou Hao Zhou Jian Zhou Jian-Xin Zhou Qin-Song Zhou Shi-Yu Zhou Xiang Zhou Xiao-Kang Zhou Xiao-Rong Zhou Ya-Jin Zhou Yi Zhou Yi-Mei Zhou Ze-Ran Zhou Bing Zhu Jing-Yu Zhu Jing-Ya Zhu Lin Zhu Rui-Lin Zhu Xing-Hao Zhu Ying-Chun Zhu Zian Zhu Mikhail Zobov Yang Zong Bing-Song Zou Ye Zou Jian Zu
- 机构 Anhui University of Science and Technology Beihang University Beijing Normal University Budker INP and Novosibirsk State University,Novosibirsk Budker Institute of Nuclear Physics,Novosibirsk Central China Normal University Central South University Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional,Mexico City Chengdu University of Technology China Institute of Atomic Energy China Spallation Neutron Source China University of Geosciences（Wuhan） Chongqing University Cornell University DESY Research Centre in Hamburg,Hamburg Ecole Polytechnique Flight Technology Research Institute Fudan University GSI Helmholtzzentrum Für Schwerionenforschung GmbH,Darmstadt Guangxi Normal University Guangxi University Guangzhou University Guizhou Minzu University Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences Hangzhou Normal University Hebei Normal University Hebei University Hefei Institutes of Physical Science,Chinese Academy of Sciences Hefei University of Technology Helmholtz Institute Mainz Henan Normal University Henan University Henan University of Techology High Energy Accelerator Research Organization,Tsukuba High Magnetic Field Laboratory,Chinese Academy of Sciences HISKP,Bonn University HSE University Huazhong University of Science and Technology Hunan University Hunan University of Science and Technology Huzhou University IFIC-University of Valencia,Valencia INFN Bologna,Bologna INFN-Laboratori Nazionali di Frascati,Frascati Inner Mongolia University Institute for Nuclear Research of the Russian Academy of Sciences Institute of Advanced Light Source Facilities Institute of Engineering Thermophysics,Chinese Academy of Sciences Institute of High Energy Physics,Chinese Academy of Sciences Institute of Modern Physics,Chinese Academy of Sciences Institute of Theoretical Physics,Chinese Academy of Sciences International Center for Theoretical Physics Asia-Pacific（ICTP-AP）,University of Chinese Academy of Sciences Istinye University,Istanbul Jiangsu Normal University Jilin University Jingchu University of Technology Johannes Gutenberg-Universität Joint Institute for Nuclear Research Kunming University Lanzhou University Liaoning Normal University Liaoning University LPNHE,Sorbonne Universit Monash University,Melbourne Nanjing Normal University Nanjing University Nanjing University of Posts and Telecommunications Nankai University National University of Defense Technology North China Electric Power University Northwest Minzu University Northwestern Polytechnical University P.N.Lebedev Physical Institute of the Russian Academy of Sciences Peking University Renmin University of China Ruhr-University Bochum Sapienza UniversitàDi Roma Shaanxi Normal University Shandong Management University Shandong University Shandong University of Technology Shandong University Shanghai Advanced Research Institute Shanghai Jiao Tong University Shanghai Normal University Shantou University Sichuan University Siemens Shenzhen Magnetic Resonance Ltd. Soochow University South China Normal University Southeast University Sun Yat-Sen University The Chinese University of Hong Kong The Cockcroft Institute,Daresbury The Institute of Mathematical Sciences,Chennai Tsinghua University U.Europea Valencia,Valencia Universidad Cardenal Herrera-CEU,CEU Universities,Valencia Universidad de Castilla-La Mancha,Ciudad Real Universidad de La Serena,La Serena Universidad Pablo de Olavide,Seville University of Barcelona,Barcelona University of Chinese Academy of Sciences University of Jinan University of Science and Technology of China University of South China University of Washington,Seattle UniversitéParis-Saclay,CNRS/IN2P3 Wuhan University Xi’an Jiaotong University Xi’an Superconducting Magnet Technologies Co. Yantai University Zhejiang University Zhengzhou University
- 出处 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2025年第12期8-177,共170页
- 基金 supported by the National Key Research and Development Program of China(No.2022YFA1602200) the National Natural Science Foundation of China(Nos.12341501 and 12405174) the Hefei Comprehensive National Science Center for the strong support on the STCF key technology research project.
- 摘要 Electron-positron colliders operating in the GeV center-of-mass range,or tau-charm energy region,have been proved to enable competitive frontier research due to several unique features.With the progress of high-energy physics in the last two decades,a new-generation Tau-Charm factory,called the Super Tau-Charm Facility(STCF),has been actively promoted by the particle physics community in China.STCF has the potential to address fundamental questions such as the essence of color confinement and the matter-antimatter asymmetry within the next decades.The main design goals of the STCF are a center-of-mass energy ranging from 2 to 7 GeV and a luminosity surpassing 5×1034cm−2s−1that is optimized at a center-of-mass energy of 4 GeV,which is approximately 50 times that of the currently operating Tau-Charm factory-BEPCII.The STCF accelerator has two main parts:a double-ring collider with a crab-waist collision scheme and an injector that provides top-up injections for both electron and positron beams.As a typical third-generation electron-positron circular collider,the STCF accelerator faces many challenges in both accelerator physics and technology.In this paper,the conceptual design of the STCF accelerator complex is presented,including the ongoing efforts and plans for technological research and develop-ment,as well as the required infrastructure.The STCF project aims to secure support from the Chinese central government for its construction during the 15th Five-Year Plan(2026-2030).
- 关键词 Third-generation electron-positron collider Super high-luminosity Tau-charm physics Crab-waist collision scheme Touschek lifetime
- 分类号 O572.21 [理学—粒子物理与原子核物理]
- 题名Color-tunable multi-stimuli-responsive luminescent system based on diarylethene and photoacid 认领 引用 被引量：1
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- 作者 Hong-Guang Fu Xuan Wu Hui-Juan Wang Fanjun Zhang Yong Chen Jing Xu
- 机构 College of Chemistry and Material Science,Shandong Agricultural University College of Forestry,Shandong Agricultural University School of Chemistry and Chemical Engineering,Qufu Normal University Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology,School of Chemistry and Chemical Engineering,Liaocheng University College of Chemistry,State Key Laboratory of Elemento-Organic Chemistry,Nankai University
- 出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第8期326-330,共5页
- 基金 financially supported by Natural Science Foundation of Shandong Province(Nos.ZR2022QB061,2022KJ181) National Key R&D Program of China(No.2023YFD1700903)。
- 摘要 The development of multi-stimuli-responsive luminescent system to address emerging demands is essential in anti-counterfeiting field.Herein,a photoswitchable system was reported,which was constructed from photoacid sulfonato-merocyanine(MEH-D)serving as H+donor and diarylethene derivative(DAEA1)as acceptor.After capturing 2 equiv.HCl,the obtained fluorescent molecule DAE-A1-H showed solvatochromic property.Further on,benefiting from that MEH-D released protons and became a ring-closed isomer spiropyran(SP-D)under 440 nm irradiation,DAE-A1 was protonated,turning on fluorescence effect was realized in DAE-A1/MEH-D.In dark,a photo-activated reversible process was realized with SPD changed to MEH-D in situ system.In addition,the OF-DAE-A1-H/SP-D could efficiently and reversibly switch on/off its luminescence upon irradiation by UV–vis light.Significantly,the multi-stimuli-responsive system was successfully applied in logic gate and fluorescence ink,making it an efficient strategy for information encryption and decryption with higher security requirements.
- 关键词 Multi-stimuli-responsive luminescent system Diarylethene photoacid Logic gate Anti-counterfeiting
- 分类号 TB34 [一般工业技术—材料科学与工程]
- 题名FSMMTD: A Feature Subset-Based Malicious Traffic Detection Method 认领 引用 被引量：1
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- 作者 Xuan Wu Yafei Song Xiaodan Wang Peng Wang Qian Xiang
- 机构 College of Air and Missile Defense,Air Force Engineering University Laboratory of Intelligent Control,PLA Rocket Force University of Engineering
- 出处 《Computers, Materials & Continua》 SCIE EI 2025年第7期1279-1305,共27页
- 基金 funded by the National Natural Science Foundation of China,grant numbers 61876189,61703426,and 61273275.
- 摘要 With the growth of the Internet of Things(IoT)comes a flood of malicious traffic in the IoT,intensifying the challenges of network security.Traditional models operate with independent layers,limiting their effectiveness in addressing these challenges.To address this issue,we propose a cross-layer cooperative Feature Subset-Based Malicious Traffic Detection(FSMMTD)model for detecting malicious traffic.Our approach begins by applying an enhanced random forest method to adaptively filter and retain highly discriminative first-layer features.These processed features are then input into an improved state-space model that integrates the strengths of recurrent neural networks(RNNs)and transformers,enabling superior processing of complex patterns and global information.This integration allows the FSMMTD model to enhance its capability in identifying intricate data relationships and capturing comprehensive contextual insights.The FSMMTD model monitors IoT data flows in real-time,efficiently detecting anomalies and enabling rapid response to potential intrusions.We validate our approach using the publicly available ToN_IoT dataset for IoT traffic analysis.Experimental results demonstrate that our method achieves superior performance with an accuracy of 98.37%,precision of 96.28%,recall of 95.36%,and F1-score of 96.79%.These metrics indicate that the FSMMTD model outperforms existing methods in detecting malicious traffic,showcasing its effectiveness and reliability in enhancing IoT network security.
- 关键词 Network security malicious traffic detection internet of things
- 分类号 TP393.08 [自动化与计算机技术—计算机应用技术]
- 题名Developing the occupational skills qualifications framework for floral designer education and training in the floristry industry 认领 引用 被引量：1
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- 作者 Xuan Wu William J.McKinley Charles R.Hall
- 机构 Texas A&M AgriLife Extension,College Station Department of Horticultural Sciences,Texas A&M University,College Station
- 出处 《Technology in Horticulture》 2025年第1期238-245,共8页
- 摘要 Retail florists,integral to the floristry industry,are experiencing workforce challenges due to an aging population and a shortage of well-trained entrants.New talent recruitment and retention are critical to the sustainability and prosperity of the profession and its associated industries.Occupational skill standards assist in identifying competencies for success in the profession.This research established skills profiles of floral designers in the U.S.by examining occupational skills standards from the United Kingdom(U.K.),Finland,India,and Singapore.The framework outlines competencies needed for progression from entry-level to master-level designers,detailing roles,tasks,knowledge,and abilities to address challenges,and autonomy of work at each level.Ten competency categories were identified across all levels.This framework can serve as a foundation for career development strategies,elevating professionalism and boosting workforce competitiveness.Through adoption,along with other recommended strategies to address labor shortage issues,the floristry industry can enhance its ability to attract,train,and retain skilled designers,ensuring long-term growth and sustainability.
- 关键词 occupational skills standards skill standards workforce challenges skills profiles floral design floral designers qualifications framework identifying competencies
- 分类号 C975 [经济管理—劳动经济] F316.13
- 题名Evaluating the practicality of the educational and occupational frameworks for floral designer education and training in the floristry industry 认领 引用
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- 作者 Xuan Wu William J.McKinley Charles R.Hall
- 机构 Texas A&M AgriLife Extension,College Station Department of Horticultural Sciences,Texas A&M University,College Station
- 出处 《Technology in Horticulture》 2025年第1期195-200,共6页
- 摘要 The floristry industry faces enduring challenges,including an aging workforce,workforce shortages,and competition from mass-produced floral products.These challenges hinder the sector's growth and competitiveness.To address these issues,the Texas A&M University floral design team developed two comprehensive frameworks:an Educational and Career Pathways framework and an Occupational Skills Qualifications framework.These frameworks aim to support floral designer training and advancement.This study evaluates the practicality of these frameworks through feedback from industry professionals on the relevance of ten core competencies critical to various career levels in floral design.Survey findings indicate that 80%of respondents are inclined to adopt the educational framework,and 88%expressed interest in the occupational framework,recognizing their potential to standardize skills,enhance career development,and elevate professional standards.The frameworks show promise as tools to attract new talent and support sustained industry growth,positioning them as essential resources for strengthening the floristry industry.
- 关键词 floral design workforce shortages occupational skills qualifications frameworkthese professional standards occupational skills qualifications educational career pathways framework floral designer educational framework
- 分类号 S688.2 [农业科学—观赏园艺] G712 [农业科学—园艺学]
- 题名Back-n white neutron source at CSNS and its applications 认领 引用 被引量：52
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- 作者 Jing-Yu Tang Qi An Jiang-Bo Bai Jie Bao Yu Bao Ping Cao Hao-Lei Chen Qi-Ping Chen Yong-Hao Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Xing-Yan Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Yi-Wei Yang Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu The CSNS Back-n Collaboration
- 机构 State Key Laboratory of Particle Detection and Electronics,Institute of High Energy Physics,Chinese Academy of Sciences Department of Modern Physics,University of Science and Technology of China Institute of Nuclear Physics and Chemistry,China Academy of Engineering Physics Key Laboratory of Nuclear Data,China Institute of Atomic Energy Institute of High Energy Physics,Chinese Academy of Sciences Spallation Neutron Source Science Center State Key Laboratory of Nuclear Physics and Technology,School of Physics,Peking University Northwest Institute of Nuclear Technology University of Chinese Academy of Sciences Department of Engineering and Applied Physics,University of Science and Technology of China State Key Laboratory of Particle Detection and Electronics,University of Science and Technology of China
- 出处 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2021年第1期95-104,共10页
- 基金 jointly supported by the National Key Research and Development Program of China(No.2016YFA0401600) National Natural Science Foundation of China(Nos.11235012 and 12035017) +1 种基金 the CSNS Engineering Project the Back-n Collaboration Consortium fund。
- 摘要 Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n white neutron source),which was completed in March 2018.The Back-n neutron beam is very intense,at approximately 29107 n/cm2/s at 55 m from the target,and has a nominal proton beam with a power of 100 kW in the CSNS-I phase and a kinetic energy of 1.6 GeV and a thick tungsten target in multiple slices with modest moderation from the cooling water through the slices.In addition,the excellent energy spectrum spanning from 0.5 eV to 200 MeV,and a good time resolution related tothe time-of-flight measurements make it a typical white neutron source for nuclear data measurements;its overall performance is among that of the best white neutron sources in the world.Equipped with advanced spectrometers,detectors,and application utilities,the Back-n facility can serve wide applications,with a focus on neutron-induced cross-sectional measurements.This article presents an overview of the neutron beam characteristics,the experimental setups,and the ongoing applications at Backn.
- 关键词 White neutron source Nuclear data measurements Experimental setups Neutron applications
- 分类号 O571.5 [理学—粒子物理与原子核物理]
- 题名Measurement of the neutron total cross section of carbon at the Back-n white neutron beam of CSNS 认领 引用 被引量：16
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- 作者 Xing-Yan Liu Yi-Wei Yang Rong Liu Jie Wen Zhong-Wei Wen Zi-Jie Han Zhi-Zhou Ren Qi An Huai-Yong Bai Jie Bao Ping Cao Qi-Ping Chen Yong-Hao Chen Pin-Jing Cheng Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Min-Hao Gu Feng-Qin Guo Chang-Cai Han Guo-Zhu He Yong-Cheng He Yue-Feng He Han-Xiong Huang Wei-Ling Huang Xi-Ru Huang Xiao-Lu Ji Xu-Yang Ji Hao-Yu Jiang Wei Jiang Han-Tao Jing Ling Kang Ming-Tao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Shu-Bin Liu Guang-Yuan Luan Ying-Lin Ma Chang-Jun Ning Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Hong Sun Xiao-Yang Sun Zhi-Jia Sun Zhi-Xin Tan Hong-Qing Tang Jing-Yu Tang Peng-Cheng Wang Qi Wang Tao-Feng Wang Yan-Feng Wang Zhao-Hui Wang Zheng Wang Qing-Biao Wu Xiao-Guang Wu Xuan Wu Li-Kun Xie Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Jing Zhang Lin-Hao Zhang Li-Ying Zhang Qing-Min Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Ying-Tan Zhao Liang Zhou Zu-Ying Zhou Dan-Yang Zhu Ke-Jun Zhu Peng Zhu
- 机构 Institute of Nuclear Physics and Chemistry,China Academy of Engineering Physics State Key Laboratory of Particle Detection and Electronics,Chinese Academy of Sciences（CAS） Department of Modern Physics,University of Science and Technology of China State Key Laboratory of Nuclear Physics and Technology,School of Physics,Peking University Key Laboratory of Nuclear Data,China Institute of Atomic Energy Institute of High Energy Physics,Chinese Academy of Sciences（CAS） Spallation Neutron Source Science Center University of South China Northwest Institute of Nuclear Technology Department of Engineering and Applied Physics,University of Science and Technology of China Beihang University Xi’an Jiaotong University
- 出处 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2019年第9期73-82,共10页
- 基金 supported by the National Key Research and Development Plan(No.2016YFA0401603) the National Natural Science Foundation of China(No.11675155)
- 摘要 To verify the performance of the neutron total cross-sectional spectrometer,the neutron total cross section of carbon is initially measured in the energy range of 1 eV to 20 MeV using the time-of-flight method.The measurement is performed at the Back-n white neutron source with a 76-m time-of-flight path using the China Spallation Neutron Source.A multilayer fast fission chamber with 235U and 238U is employed as the neutron detector.The diameter and thickness of the natural graphite sample are 70 mm and 40 mm,respectively.Signal waveforms are collected using a data acquisition system.Off-line data processing was used to obtain the neutron time-of-flight spectra and transmissions.The uncertainty of the counting statistics is generally approximately 3%for each bin in the energy range of 1–20 MeV.It is determined that the results for the neutron total cross section of carbon obtained using^235U cells are in good agreement with the results obtained using 238U cells within limits of statistical uncertainty.Moreover,the measured total cross sections show good agreement with the broadening evaluated data.
- 关键词 CSNS Back-n white neutron source NTOX Neutron total cross section Carbon Multilayer fast fission chamber
- 分类号 O571.5 [理学—粒子物理与原子核物理]
- 题名A Wheeled Wall-Climbing Robot with Bio-Inspired Spine Mechanisms 认领 引用 被引量：25
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- 作者 Yanwei Liu Shaoming Sun Xuan Wu Tao Mei
- 机构 Department of Precision Machinery and Precision Instrumentation,University of Science and Technology of China Institute of Advanced Manufacturing and Technology,Hefei Institute of Physical Science,Chinese Academy of Sciences
- 出处 《Journal of Bionic Engineering》 SCIE EI CSCD 2015年第1期17-28,共12页
- 基金 Acknowledgment This work was supported by National Basic Re- search Program of China （No.2011 CB302106）, National Natural Science Foundation of China （No. 51005223） and Changzhou Science and Technology Support Pro- gram （CE20120081）. The authors would like to thank Dr Xiaojie Wang for his valuable advice and kind help in preparing this manuscript.
- 摘要 This paper presents a wheeled wall-climbing robot with the ability to climb concrete, brick walls using circular arrays of miniature spines located around the wheel. The robot consists of two driving wheels and a flexible tail, just like letter “T”, so it is called Tbot. The simple and effective structure of Tbot enables it to be steerable and to transition from horizontal to vertical surfaces rapidly and stably. Inspired by the structure and mechanics of the tarsal chain in the Serica orientalis Motschulsky, a compliant spine mechanism was developed. With the bio-inspired compliant spine mechanism, the climbing performance of Tbot was improved. It could climb on 100° （10° past vertical） brick walls at a speed of 10 cm·s^-1. A mechanical model is also presented to analyze the forces acting on spine during a climbing cycle as well as load share between multi-spines. The simu- lation and experiment results show that the mechanical model is suitable and useful in the optimum design of Tbot.
- 关键词 biologically-inspired robots climbing robots compliant spine mechanisms mechanical model wheeled robots
- 分类号 TP242 [自动化与计算机技术—检测技术与自动化装置]
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- 题名Measurement of the 232Th(n,f)cross section in the 1-200 MeV range at the CSNS Back-n 认领 引用 被引量：8
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- 作者 Zhi-Zhou Ren Yi-Wei Yang Yong-Hao Chen Rong Liu Bang-Jiao Ye Jie Wen Hai-Rui Guo Zi-Jie Han Qi-Ping Chen Zhong-Wei Wen Wei-Li Sun Han Yi Xing-Yan Liu Tao Ye Jiang-Bo Bai Qi An Jie Bao Yu Bao Ping Cao Hao-Lei Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Shu-Bin Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Jing-Yu Tang Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu
- 机构 Department of Modern Physics,University of Science and Technology of China Institute of Nuclear Physics and Chemistry,China Academy of Engineering Physics Institute of High Energy Physics,Chinese Academy of Sciences（CAS） Spallation Neutron Source Science Center Institute of Applied Physics and Computational Mathematics State Key Laboratory of Particle Detection and Electronics,University of Science and Technology of China Key Laboratory of Nuclear Data,China Institute of Atomic Energy School of Nuclear Science and Technology,University of Science and Technology of China State Key Laboratory of Nuclear Physics and Technology,School of Physics,Peking University State Key Laboratory of Particle Detection and Electronics,Institute of High Energy Physics,Chinese Academy of Sciences Northwest Institute of Nuclear Technology University of Chinese Academy of Sciences Department of Engineering and Applied Physics,University of Science and Technology of China
- 出处 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第8期142-153,共12页
- 基金 supported by the National Natural Science Foundation of China(Nos.11675155,11790321,and 12075216) the National Key Research and Development Plan(No.2016YFA0401603).
- 摘要 The 232Th(n,f)cross section is very important in basic nuclear physics and applications based on the Th/U fuel cycle.Using the time-of-flight method and a multi-cell fast-fission ionization chamber,a novel measurement of the232Th(n,f)cross sec-tion relative to235U in the 1–200 MeV range was performed at the China Spallation Neutron Source Back-n white neutron source(Back-n).The fission event-neutron energy spectra of232Th and235U fission cells were measured in the single-bunch mode.Corrected 232Th/235U fission cross-sectional ratios were obtained,and the measurement uncertainties were 2.5–3.7%for energies in the 2–20 MeV range and 3.6–6.2%for energies in the 20–200 MeV range.The232Th(n,f)cross section was obtained by introducing the standard cross section of235U(n,f).The results were compared with those of previous theoreti-cal calculations,measurements,and evaluations.The measured 232Th fission cross section agreed with the main evaluation results in terms of the experimental uncertainty,and 232Th fission resonances were observed in the 1–3 MeV range.The present results provide232Th(n,f)cross-sectional data for the evaluation and design of Th/U cycle nuclear systems.
- 关键词 232Th(n f)cross section Fast-fission ionization chamber Back-n white neutron source
- 分类号 O571.5 [理学—粒子物理与原子核物理]
- 题名From static to dynamic:live observation of the support system after ischemic stroke by two photon-excited fluorescence laser-scanning microscopy 认领 引用 被引量：5
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- 作者 Xuan Wu Jia-Rui Li Yu Fu Dan-Yang Chen Hao Nie Zhou-Ping Tang
- 机构 Department of Neurology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Province Department of Geriatrics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Province
- 出处 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第10期2093-2107,共15页
- 基金 supported by grants from the National Natural Science Foundation of China,Nos.92148206,82071330(to ZPT) 82201745(to HN) the Natural Science Foundation of Hubei Province,China,Nos.2021BCA109(to ZPT)and 2021CFB067(to HN)。
- 摘要 Ischemic stroke is one of the most common causes of mortality and disability worldwide.However,treatment efficacy and the progress of research remain unsatisfactory.As the critical support system and essential components in neurovascular units,glial cells and blood vessels(including the bloodbrain barrier)together maintain an optimal microenvironment for neuronal function.They provide nutrients,regulate neuronal excitability,and prevent harmful substances from entering brain tissue.The highly dynamic networks of this support system play an essential role in ischemic stroke through processes including brain homeostasis,supporting neuronal function,and reacting to injuries.However,most studies have focused on postmortem animals,which inevitably lack critical information about the dynamic changes that occur after ischemic stroke.Therefore,a high-precision technique for research in living animals is urgently needed.Two-photon fluorescence laser-scanning microscopy is a powerful imaging technique that can facilitate live imaging at high spatiotemporal resolutions.Twophoton fluorescence laser-scanning microscopy can provide images of the whole-cortex vascular 3D structure,information on multicellular component interactions,and provide images of structure and function in the cranial window.This technique shifts the existing research paradigm from static to dynamic,from flat to stereoscopic,and from single-cell function to multicellular intercommunication,thus providing direct and reliable evidence to identify the pathophysiological mechanisms following ischemic stroke in an intact brain.In this review,we discuss exciting findings from research on the support system after ischemic stroke using two-photon fluorescence laser-scanning microscopy,highlighting the importance of dynamic observations of cellular behavior and interactions in the networks of the brain’s support systems.We show the excellent application prospects and advantages of two-photon fluorescence laser-scanning microscopy and predict future research developments and directions in the study of ischemic stroke.
- 关键词 astrocytes blood-brain barrier calcium signaling glymphatic system ischemic stroke microglia network remodel two-photon fluorescence laser-scanning microscopy vessels
- 分类号 R743.3 [医药卫生—神经病学与精神病学]
- 题名A discussion on evaluation criteria for crevice corrosion of various stainless steels 认领 引用 被引量：6
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- 作者 Xuan Wu Yuanyuan Liu Yangting Sun Nianwei Dai Jin Li Yiming Jiang
- 机构 Department of Materials Science,Fudan University
- 出处 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2021年第5期29-37,共9页
- 基金 financially supported by the National Natural Science Foundation of China(Nos.51671059,51871061 and 51801028)。
- 摘要 In this study,crevice corrosion performances of a newly developed LDSS 2002 and three commercial stainless steels(AISI 304,AISI 316L and DSS 2205)were investigated and discussed.Crevice repassivation potential(ER,CREV),which was measured by the potentiodynamic-galvanostatic-potentiodynamic(PDGS-PD)test,was applicable to crevice corrosion evaluation of 304 and 316 L stainless steels.However,much lower(ER,CREV values were obtained for DSS 2205 and LDSS 2002.These abnormal(ER,CREV values for duplex stainless steels may be related to the selective attack of the less corrosion-resistant phase,the lower corrosion potential in the crevice-like solution,and more crevice corrosion sites in the PD-GS-PD test.A critical chloride concentration of crevice corrosion(CCCCREV)measurement was introduced for crevice corrosion evaluation of various stainless steels.The derived CCCCREVwas proved to be a valid criterion for crevice corrosion evaluation of both the austenitic and duplex stainless steels.An order of crevice corrosion resistance of AISI 304≈LDSS 2002<AISI 316 L<DSS 2205 was suggested,which agreed well with the orders of pitting resistance equivalent number and critical crevice index of the less corrosion-resistant phase in each material.
- 关键词 Stainless steel Crevice corrosion Crevice repassivation potential Critical chloride concentration
- 分类号 TG172.2 [金属学及工艺—金属表面处理]
- 题名Petrogenesis of the Late Triassic shoshonitic Shadegai pluton from the northern North China Craton: Implications for crust-mantle interaction and post-collisional extension 认领 引用 被引量：3
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- 作者 Liqiong Jia Liang Wang Genhou Wang Shibin Lei Xuan Wu
- 机构 Development Research Center,China Geological Survey National Geological Archive of China Gold Geology Institute of Chinese Armed Police Force School of Earth Sciences and Resources,China University of Geosciences （Beijing） Headquarters of Gold Exploration Branch of Chinese Armed Police Force
- 出处 《Geoscience Frontiers》 SCIE CAS CSCD 2019年第2期595-610,共16页
- 基金 supported by the Land and Resources Survey Project of China (Grant Nos. 1212011120725 and 12120113072200)
- 摘要 Latest Permian to Triassic plutons are widespread in the northern North China Craton(NCC); most of them show calc-alkaline, high-K calc-alkaline, or alkaline geochemical features. The Shadegai pluton in the Wulashan area has shoshonitic affinity and I-type character, and is composed of syenogranites containing abundant mafic microgranular enclaves(MMEs). LA-MC-ICP-MS U-Pb data yield weighted mean 206 Pb/238 U ages of 222 ± 1 Ma and 221 ± 1 Ma for the syenogranites and MMEs, respectively, suggesting their coeval formation during the Late Triassic. The syenogranites have high SiO_2(70.42-72.30 wt%),K_2O(4.58-5.22 wt.%) and Na_2O(4.19-4.43 wt.%) contents but lower concentrations of P_2O_5(0.073-0.096 wt.%) and TiO_2(0.27-0.37 wt.%), and are categorized as I-type granites, rather than A-type granites, as previously thought. These syenogranites exhibit lower(87Sr/86Sr)i ratios(0.70532-0.70547) and strongly negative whole-rock εNd(t) values(-12.54 to-11.86) and zircon εHf(t) values(-17.81 to-10.77),as well as old Nd(1962-2017 Ma) and Hf(2023-2092 Ma) model ages, indicating that they were derived from the lower crust.Field and petrological observations reveal that the MMEs within the pluton probably represent magmatic globules commingled with their host magmas. Geochemically, these MMEs have low SiO_2(53.46-55.91 wt.%)but high FeOt(7.27-8.79 wt.%) contents. They are enriched in light rare earth elements(LREEs) and large ion lithophile elements(LILEs), and are depleted in heavy rare earth elements(HREEs) and high field strength elements(HFSEs). They have whole-rock(87Sr/86Sr)i ratios varying from 0.70551 to 0.70564, εNd(t) values of -10.63 to -9.82, and zircon εHf(t) values of -9.89 to 0.19. Their geochemical and isotopic features indicate that they were derived from the subcontinental lithospheric mantle mainly metasomatized by slab-derived fluids, with minor involvement of melts generated from the ascending asthenospheric mantle. Petrology integrated with elemental and isotopic geochemistry suggest that the Shadegai pluton was produced by crust-mantle interactions, i.e., partial melting of the lower continental crust induced by underplating of mantle-derived mafic magmas(including the subcontinental lithospheric mantle and asthenospheric mantle), and subsequent mixing of the mantle-and crust-derived magmas. In combination with existing geological data, it is inferred that the Shadegai pluton formed in a post-collisional extensional regime related to lithospheric delamination following the collision between the NCC and Mongolia arc terranes.
- 关键词 Magma mixing Crust-mantle interaction Lithospheric delamination Post-collision North China Craton
- 分类号 P534.51 [天文地球—古生物学与地层学] P588.1 [天文地球—地质学] P542
- 题名In-beam gamma rays of CSNS Back-n characterized by black resonance filter 认领 引用 被引量：5
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- 作者 Jin-Cheng Wang Jie Ren Wei Jiang Xi-Chao Ruan Ying-Yi Liu Hao-Lan Yang Kuo-Zhi Xu Xin-Yi Pan Qi Sun Jie Bao Han-Xiong Huang Hao-Fan Bai Jiang-Bo Bai Ping Cao Qi-Ping Chen Yong-Hao Chen Wen-Hao Duan An-Chuan Fan Rui-Rui Fan Chang-Qing Feng Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Zhi-Jie Jiang Ling Kang Chang-Lin Lan Bo Li Feng Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Yi-Na Liu Guang-Yuan Luan Chang-Jun Ning Yi-Jia Qiu Wen-Kai Ren Zhi-Zhou Ren Zhao-Hui Song Kang Sun Zhi-Xin Tan Jing-Yu Tang Sheng-Da Tang Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Ze-Peng Wu Cong Xia Li-Kun Xie Han Yi Tao Yu Yong-Ji Yu Guo-Hui Zhang Hang-Chang Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Mao-Yuan Zhao Zhi-Hao Zhou Ke-Jun Zhu Chong Zou
- 机构 Key Laboratory of Nuclear Data,China Institute of Atomic Energy Institute of High Energy Physics,Chinese Academy of Sciences（CAS） Spallation Neutron Source Science Center State Key Laboratory of Nuclear Physics and Technology,School of Physics,Peking University Institute of Modern Physics,Fudan University State Key Laboratory of Particle Detection and Electronics,University of Science and Technology of China School of Nuclear Science and Technology,University of Science and Technology of China Institute of Nuclear Physics and Chemistry,China Academy of Engineering Physics Department of Modern Physics,University of Science and Technology of China USTC Archaeometry Lab,University of Science and Technology of China State Key Laboratory of Particle Detection and Electronics,Institute of High Energy Physics Chinese Academy of Sciences Northwest Institute of Nuclear Technology University of Chinese Academy of Sciences School of Nuclear Science and Technology,Lanzhou University Institute of Advanced Technology,University of Science and Technology of China
- 出处 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第10期149-160,共12页
- 基金 supported by the Youth Talent Program of China National Nuclear Corporation the Continuous-Support Basic Scientific Research Project(BJ010261223282) +1 种基金 the National Natural Science Foundation of China(No.11790321) the Research and development project of China National Nuclear Corporation。
- 摘要 The back-streaming white-neutron beamline(Back-n)of the China Spallation Neutron Source is an essential neutronresearch platform built for the study of nuclear data,neutron physics,and neutron applications.Many types of cross-sectional neutron-reaction measurements have been performed at Back-n since early 2018.These measurements have shown that a significant number of gamma rays can be transmitted to the experimental stations of Back-n along with the neutron beam.These gamma rays,commonly referred to as in-beam gamma rays,can induce a non-negligible experimental background in neutron-reaction measurements.Studying the characteristics of in-beam gamma rays is important for understanding the experimental background.However,measuring in-beam gamma rays is challenging because most gamma-ray detectors are sensitive to neutrons;thus,discriminating between neutron-induced signals and those from in-beam gamma rays is difficult.In this study,we propose the use of the black resonance filter method and a CeBr3 scintillation detector to measure the characteristics of the in-beam gamma rays of Back-n.Four types of black resonance filters,181Ta,59Co,natAg,andnatCd,were used in this measurement.The time-of-flight(TOF)technique was used to select the detector signals remaining in the absorption region of the TOF spectra,which were mainly induced by in-beam gamma rays.The energy distribution and flux of the in-beam gamma rays of Back-n were determined by analyzing the deposited energy spectra of the CeBr3 scintillation detector and using Monte Carlo simulations.Based on the results of this study,the background contributions from in-beam gamma rays in neutron-reaction measurements at Back-n can be reasonably evaluated,which is beneficial for enhancing both the experimental methodology and data analysis.
- 关键词 In-beam gamma rays Back-n CeBr3scintillator Black filter resonance technique
- 分类号 O571.5 [理学—粒子物理与原子核物理]
- 题名Electropolymerization of cobalt porphyrins and corroles for the oxygen evolution reaction 认领 引用 被引量：4
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- 作者 Qingxin Zhang Yabo Wang Yanzhi Wang Shujiao Yang Xuan Wu Bin Lv Ni Wang Yimei Gao Xiaoran Xu Haitao Lei Rui Cao
- 机构 Key Laboratory of Applied Surface and Colloid Chemistry,Ministry of Education,School of Chemistry and Chemical Engineering,Shaanxi Normal University
- 出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第12期3807-3810,共4页
- 基金 support from National Natural Science Foundation of China (Nos. 21773146 and 21902099) China Postdoctoral Science Foundation (No. 2018M631120) +2 种基金 Shaanxi Province Postdoctoral Science Foundation (No. 2018BSHEDZZ107) Fundamental Research Funds for the Central Universities (Nos. GK202103045 and GK202103050) Research funds of Shaanxi Normal University, and the open fund of State Key Laboratory of Structural Chemistry。
- 摘要 Developing large-scale electrocatalysts using molecular complexes for the oxygen evolution reaction(OER)is of great importance. Herein, four cobalt porphyrins and corroles are deposited on electrode substrates using a simple and fast electropolymerization method. Our results showed that Co-1-P@CC, formed by electropolymerizing Co tetrakis(p-N-pyrrolylphenyl)porphyrin(Co-1-P) on carbon cloth(CC), is the most active OER catalyst in the examined Co porphyrins and corroles in alkaline aqueous solutions by displaying an onset overpotential of 380 m V. Long-term electrolysis tests confirmed the stability of these electropolymerized films by functioning as OER electrocatalysts.
- 关键词 Cobalt corroles Cobalt porphyrins Electropolymerization Molecular electrocatalysis Oxygen evolution
- 分类号 TQ116.2 [化学工程—无机化工] TQ426
- 题名Boosting extraction of Pb in contaminated soil via interfacial solar evaporation of multifunctional sponge 认领 引用 被引量：3
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- 作者 Pan Wu Xuan Wu Yida Wang Jingyuan Zhao Haolan Xu Gary Owens
- 机构 Future Industries Institute,UniSA STEM,University of South Australia,Mawson Lakes Campus
- 出处 《Green Energy & Environment》 SCIE EI CAS CSCD 2023年第5期1459-1468,共10页
- 基金 H.Xu acknowledges the financial support from the Australian Research Council(FT190100485,DP220100583) P.W.acknowledge financial support from the China Scholarship Council for primary scholarships and from the Future Industries Institute for top up scholarships.All authors acknowledge the use of Microscopy Australia facilities located at the University of South Australia,infrastructure co-funded by the University of South Australia,the South Australian State Government,and the Australian Federal Government's National Collaborative Research Infrastructure Strategy(NCRIS)scheme.
- 摘要 Interfacial solar water evaporation is a reliable way to accelerate water evaporation and contaminant remediation.Embracing the recent advance in photothermal technology,a functional sponge was prepared by coating a sodium alginate(SA)impregnated sponge with a surface layer of reduced graphene oxide(rGO)to act as a photothermal conversion medium and then subsequently evaluated for its ability to enhance Pb extraction from contaminated soil driven by interfacial solar evaporation.The SA loaded sponge had a Pb adsorption capacity of 107.4 mg g-1.Coating the top surface of the SA sponge with rGO increased water evaporation performance to 1.81 kg m-2h-1in soil media under one sun illumination and with a wind velocity of 2 m s-1.Over 12 continuous days of indoor evaporation testing,the Pb extraction efficiency was increased by 22.0%under 1 sun illumination relative to that observed without illumination.Subsequently,Pb extraction was further improved by 48.9%under outdoor evaporation conditions compared to indoor conditions.Overall,this initial work shows the significant potential of interfacial solar evaporation technologies for Pb contaminated soil remediation,which should also be applicable to a variety of other environmental contaminants.
- 关键词 Photothermal materials Interfacial solar evaporation Reduced graphene oxide Pb extraction Soil remediation
- 分类号 X53 [环境科学与工程—环境工程]
