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Pulsed Dynamic Water Electrolysis:Mass Transfer Enhancement,Microenvironment Regulation,and Hydrogen Production Optimization 认领 引用
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作者 Xuewei Zhang Wei Zhou +7 位作者 Xiaoxiao Meng Yuming Huang Yang Yu Haiqian Zhao Lijie Wang Fei Sun Jihui Gao Guangbo Zhao 《Nano-Micro Letters》 SCIE EI CAS CSCD 2026年第3期807-859,共53页
Pulsed dynamic electrolysis(PDE),driven by renewable energy,has emerged as an innovative electrocatalytic conversion method,demonstrating significant potential in addressing global energy challenges and promoting sust... Pulsed dynamic electrolysis(PDE),driven by renewable energy,has emerged as an innovative electrocatalytic conversion method,demonstrating significant potential in addressing global energy challenges and promoting sustainable development.Despite significant progress in various electrochemical systems,the regulatory mechanisms of PDE in energy and mass transfer and the lifespan extension of electrolysis systems,particularly in water electrolysis(WE)for hydrogen production,remain insufficiently explored.Therefore,there is an urgent need for a deeper understanding of the unique contributions of PDE in mass transfer enhancement,microenvironment regulation,and hydrogen production optimization,aiming to achieve low-energy consumption,high catalytic activity,and long-term stability in the generation of target products.Here,this review critically examines the microenvironmental effects of PDE on energy and mass transfer,the electrode degradation mechanisms in the lifespan extension of electrolysis systems,and the key factors in enhancing WE for hydrogen production,providing a comprehensive summary of current research progress.The review focuses on the complex regulatory mechanisms of frequency,duty cycle,amplitude,and other factors in hydrogen evolution reaction(HER)performance within PDE strategies,revealing the interrelationships among them.Finally,the potential future directions and challenges for transitioning from laboratory studies to industrial applications are proposed. 展开更多
关键词 Pulsed dynamic electrolysis Water electrolysis Energy and mass transfer Microenvironment System stability
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脉冲电解水制氢:原理、技术现状及未来趋势 认领 引用
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作者 赵鹏翔 王丽杰 +9 位作者 冯少广 张学伟 朱鸿飞 孙坤元 于洋 孙苗婷 孟晓晓 高继慧 赵广播 周伟 《化学进展》 SCIE CAS CSCD 北大核心 2026年第2期194-209,共16页
氢能作为碳中和目标下的关键清洁能源载体,其高效制备技术亟待突破。本文聚焦脉冲电解水制氢技术,系统阐述其通过周期性调控电流/电压降低扩散层厚度,加速气泡脱离,提升电极稳定性的机理,揭示脉冲抑制气泡屏蔽效应,高频脉冲缩短离子弛... 氢能作为碳中和目标下的关键清洁能源载体,其高效制备技术亟待突破。本文聚焦脉冲电解水制氢技术,系统阐述其通过周期性调控电流/电压降低扩散层厚度,加速气泡脱离,提升电极稳定性的机理,揭示脉冲抑制气泡屏蔽效应,高频脉冲缩短离子弛豫时间的优化机制。文中总结了脉冲参数(波形、频率、占空比等)对制氢特性的影响规律,对比了感应脉冲、电压/电流脉冲及波动功率电解技术的应用潜力,强调其在适配风光波动性电源(宽功率调节、抑制电压闪变)中的优势。脉冲电解虽展现高能效与强鲁棒性,但仍面临电极抗冲击性不足、多参数耦合机制不明等瓶颈。未来需融合智能算法优化动态调控,发展风光储氢一体化系统,推动高频谐振与低纹波滤波技术应用,加速绿氢规模化生产。本文为脉冲电解技术的研发及其潜在工程化应用提供了理论支撑。 展开更多
关键词 脉冲电解 电解水制氢 能效优化 风光波动性 参数调控
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Pulsed dynamic electrolysis enhanced PEMWE hydrogen production:Revealing the effects of pulsed electric fields on protons mass transport and hydrogen bubble escape 认领 引用 被引量：5
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作者 Xuewei Zhang Wei Zhou +13 位作者 Yuming Huang Liang Xie Tonghui Li Huimin Kang Lijie Wang Yang Yu Yani Ding Junfeng Li Jiaxiang Chen Miaoting Sun Shuo Cheng Xiaoxiao Meng Jihui Gao Guangbo Zhao 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2025年第1期201-214,共14页
The transition of hydrogen sourcing from carbon-intensive to water-based methodologies is underway,with renewable energy-powered proton exchange membrane water electrolysis(PEMWE)emerging as the preeminent pathway for... The transition of hydrogen sourcing from carbon-intensive to water-based methodologies is underway,with renewable energy-powered proton exchange membrane water electrolysis(PEMWE)emerging as the preeminent pathway for hydrogen production.Despite remarkable advancements in this field,confronting the sluggish electrochemical kinetics and inherent high-energy consumption arising from deteriorated mass transport within PEMWE systems remains a formidable obstacle.This impediment stems primarily from the hindered protons mass transfer and the untimely hydrogen bubbles detachment.To address these challenges,we harness the inherent variability of electrical energy and introduce an innovative pulsed dynamic water electrolysis system.Compared to constant voltage electrolysis(hydrogen production rate:51.6 m L h-1,energy consumption:5.37 kWh Nm-3H2),this strategy(hydrogen production rate:66 m L h-1,energy consumption:3.83 kWh Nm-3H2)increases the hydrogen production rate by approximately 27%and reduces the energy consumption by about 28%.Furthermore,we demonstrate the practicality of this system by integrating it with an off-grid photovoltaic(PV)system designed for outdoor operation,successfully driving a hydrogen production current of up to 500 mA under an average voltage of approximately 2 V.The combined results of in-situ characterization and finite element analysis reveal the performance enhancement mechanism:pulsed dynamic electrolysis(PDE)dramatically accelerates the enrichment of protons at the electrode/solution interface and facilitates the release of bubbles on the electrode surface.As such,PDE-enhanced PEMWE represents a synergistic advancement,concurrently enhancing both the hydrogen generation reaction and associated transport processes.This promising technology not only redefines the landscape of electrolysis-based hydrogen production but also holds immense potential for broadening its application across a diverse spectrum of electrocatalytic endeavors. 展开更多
关键词 Water electrolysis Hydrogen production Pulsed dynamic electrolysis Proton exchange membrane water electrolysis Mass transport
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Clinical Efficacy and Adverse Reactions of VMAT Radiotherapy Combined with Raltitrexed Chemotherapy in the Treatment of Elderly Patients with Esophageal Cancer 认领 引用
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作者 Yujuan Gao Lei Yuan Xuewei Zhang 《Proceedings of Anticancer Research》 2025年第4期93-98,共6页
Objective:To investigate the efficacy and adverse reactions of volumetric modulated arc therapy(VMAT)radiotherapy combined with raltitrexed chemotherapy in the treatment of elderly patients with esophageal cancer.Meth... Objective:To investigate the efficacy and adverse reactions of volumetric modulated arc therapy(VMAT)radiotherapy combined with raltitrexed chemotherapy in the treatment of elderly patients with esophageal cancer.Methods:A total of 86 elderly patients with esophageal cancer admitted to our hospital between February 2024 and February 2025 were enrolled in this study and equally divided into two groups:a control group receiving VMAT radiotherapy alone and a study group receiving VMAT radiotherapy combined with raltitrexed chemotherapy,with 43 patients in each group,to compare the therapeutic outcomes between the two treatment approaches.Results:The study group demonstrated significantly higher objective remission and disease control rates than the control group(P0.05).Quality of life(QOL)scores were significantly elevated in the study group compared to the control group at both 3-and 6-month follow-ups(P<0.05).Conclusion:VMAT radiotherapy combined with raltitrexed chemotherapy can improve the short-term efficacy,reduce tumor marker levels,and improve the quality of life of elderly patients with esophageal cancer.The treatment has fewer adverse reactions and better patient tolerance. 展开更多
关键词 Esophageal cancer Elderly Volumetric modulated arc therapy Raltitrexed
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Corrosion form transition of mooring chain in simulated deep-sea environments:Remarkable roles of dissolved oxygen and hydrostatic pressure 认领 引用 被引量：8
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作者 Xuewei Zhang Weijie Wu +2 位作者 Yuan Li Jinxu Li Lijie Qiao 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2023年第31期118-130,共13页
The corrosion form and mechanical properties deterioration of mooring chain steel in simulated deep-sea environments were investigated.With the increase of ocean depth,not only the pressure increases,but also the diss... The corrosion form and mechanical properties deterioration of mooring chain steel in simulated deep-sea environments were investigated.With the increase of ocean depth,not only the pressure increases,but also the dissolved oxygen content decreases.These two factors affect corrosion evolution of mooring chain steel in simulated deep-sea environments,which was studied for the first time.Compared with uniform corrosion of mooring chain steel in shallow sea with sufficient oxygen,low dissolved oxygen leads to the corrosion dominated by pitting with pit covers.Meanwhile,hydrostatic pressure distinctly accelerates pitting initiation and propagation.The higher the hydrostatic pressure is,the more serious the pitting is.For failure mechanism of unstressed mooring chain steel serving in simulated deep-sea environments,both absorbed hydrogen and corrosion morphology can degrade the ductility of mooring chain steel,in which the leading factor depends on the service time.The severe pitting is the main factor and causes remarkable ductility loss of the steel after long-term immersion.But hydrogen plays an important role on elongation loss in early stage. 展开更多
关键词 High-strength low-alloy steel Dissolved oxygen Hydrostatic pressure Pitting corrosion Failure mechanism
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Key CO2capture technology of pure oxygen exhaust gas combustion for syngas-fueled high-temperature fuel cells 认领 引用 被引量：7
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作者 Hanlin Wang Qilong Lei +5 位作者 Pingping Li Changlei Liu Yunpeng Xue Xuewei Zhang Chufu Li Zhibin Yang 《International Journal of Coal Science & Technology》 EI CAS CSCD 2021年第3期383-393,共11页
Integrated gasification fuel cells(IGFCs)integrating high-temperature solid oxide fuel cell technology with CO2capture processes represents highly-efficient power systems with negligible CO2emissions.Flame burni... Integrated gasification fuel cells(IGFCs)integrating high-temperature solid oxide fuel cell technology with CO2capture processes represents highly-efficient power systems with negligible CO2emissions.Flame burning with pure oxygen is an ideal method for fuel cell exhaust gas treatment,and this report describes experimental and numerical studies regarding an oxy-combustor for treating the exhaust gas of a 10 kW IGFC system anode.The applied simulation method was verified based on experiments,and the key performance indices of the combustor were studied under various conditions.It was determined that 315 K was the ideal condensation temperature to obtain flame stability.Under these pure oxygen flame burning conditions,CO was almost completely converted,and the dry mole fraction of CO2after burning was C 0.958 when there was up to 5%excess O2.Overall,5%excess O2was recommended to maximize CO2capture and promote other environmental considerations.Additionally,the optimal tangential fuel jet angle to control the liner temperature was approximately 25°.The total fuel utilization had to be high enough to maintain the oxygen flame temperature of the anode exhaust gas below 1800 K to ensure that the system was environmentally friendly.The results presented herein have great value for designing IGFCs coupled with CO2capture systems. 展开更多
关键词 Integrated gasification fuel cell system Solid oxide fuel cell Anode exhaust gas treatment CO2capture Oxy-combustion
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Array Characteristics of Oscillating-Buoy Two-Floating-Body Wave-Energy Converter 认领 引用 被引量：2
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作者 Renwei Ji Qihu Sheng +3 位作者 Shuqi Wang Yuquan Zhang Xuewei Zhang Liang Zhang 《Journal of Marine Science and Application》 CSCD 2019年第3期325-333,共9页
As the energy supply problem worsens, the development and utilization of marine renewable energy have become a research hotspot. The development of wave energy is moving from the near shore to the distant sea. The pow... As the energy supply problem worsens, the development and utilization of marine renewable energy have become a research hotspot. The development of wave energy is moving from the near shore to the distant sea. The power-generation efficiency of a single two-floating-body wave-energy converter is relatively low. To fully utilize wave energy and improve the wave-energy capture rate of a fixed sea area, arranging a two-floating-body wave-energy converter array is necessary. This paper first introduces the basic theory of multi-floating flow field, time-domain calculation method, and influence factor of the waveenergy converter array. Then, the development of AQWA software in Fortran language considers the effect of power takeoff. A calculation method based on ANSYS–AQWA is proposed to simulate the motion of the oscillating-buoy two-floating-body wave-energy converter. The results are compared with the experimental results from the National Renewable Energy Laboratory. Finally, the ANSYS–AQWA method is used to study the power characteristics of simple and complex arrays of wave-energy converters. The average power generation of simple arrays is largest at 0°, and the average power generation of complex arrays does not change with the wave direction. Optimal layout spacing exists for the simple and complex arrays. These findings can serve as a valuable reference for the large-scale array layout of wave-energy converters in the future. 展开更多
关键词 Oscillating buoy Two-floating body Wave-energy converter AQWA Converter array Power characteristics
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Fuzzy Control Optimization of Loading Paths for Hydroforming of Variable Diameter Tubes 认领 引用 被引量：1
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作者 Yong Xu Xuewei Zhang +4 位作者 Wenlong Xie Shihong Zhang Xinyue Huang Yaqiang Tian Liansheng Chen 《Computers, Materials & Continua》 SCIE EI 2024年第11期2753-2768,共16页
The design of the loading path is one of the important research contents of the tube hydroforming process.Optimization of loading paths using optimization algorithms has received attention due to the inefficiency of o... The design of the loading path is one of the important research contents of the tube hydroforming process.Optimization of loading paths using optimization algorithms has received attention due to the inefficiency of only finite element optimization.In this paper,the hydroforming process of 5A02 aluminum alloy variable diameter tube was as the research object.Fuzzy control was used to optimize the loading path,and the fuzzy rule base was established based on FEM.The minimum wall thickness and wall thickness reduction rate were determined as input membership functions,and the axial feeds variable value of the next step was used as output membership functions.The results show that the optimized loading path greatly improves the uniformity of wall thickness and the forming effect compared with the linear loading path.The round corner lamination rate of the tube is 91.2%under the fuzzy control optimized loading path,which was increased by 47.1%and 22.6%compared with linear loading Path 1 and Path 2,respectively.Based on the optimized loading path in the experiment,the minimum wall thickness of the variable diameter tube was 1.32 mm and the maximum thinning rate was 12.4%.The experimental results were consistent with the simulation results,which verified the accuracy of fuzzy control.The research results provide a reference for improving the forming quality of thin-walled tubes and plates. 展开更多
关键词 Variable diameter tubes finite element simulation hydroforming fuzzy control
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Decellularized extracellular matrix and mesenchymal stem cells promote recovery in traumatic brain injury by synergistically enhancing neurogenesis and attenuating neuroinflammation 认领 引用
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作者 Xuewei Zhang Bixue Wang +4 位作者 Hua Hong Ying Wang Jiashang Liu Changsheng Liu Xi Chen 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2023年第7期17-28,共12页
Damaged neurons and harsh microenvironments contribute to the injury cascades following traumatic brain injury(TBI).Mesenchymal stem cell(MSC)therapy is considered a viable choice for brain in-jury treatment;however,i... Damaged neurons and harsh microenvironments contribute to the injury cascades following traumatic brain injury(TBI).Mesenchymal stem cell(MSC)therapy is considered a viable choice for brain in-jury treatment;however,its clinical use is hindered by limited engraftment,low survival ratio,and uncontrolled differentiation.Herein,the decellularized brain extracellular matrix(dBECM)was prepared through a new method as a delivery system for MSCs.dBECM-based hydrogel with favorable biochem-ical and biomechanical features provides a microenvironment for MSCs in nerve repair.The MSCs-encapsulated dBECM-based hydrogel is shown to improve neuron compensation and structural regen-eration,alleviate neuroinflammation,and promote M1-to-M2 polarization of microglia.Our results first demonstrate that the combination of dBECM and MSCs is a critical vehicle to promote TBI repair from neurogenesis and immunoregulation,showing promise for the physiological recovery of neurogenic dis-eases and injuries. 展开更多
关键词 ECM Stem cells Brain injury Neurogenesis Neuroinflammation
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A distributed approach for lidar-based relative state estimation of multi-UAV in GPS-denied environments 认领 引用 被引量：9
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作者 Hongming SHEN Qun ZONG +3 位作者 Hanchen LU Xuewei ZHANG Bailing TIAN Lei HE 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2022年第1期59-69,共11页
In this paper,we present a distributed framework for the lidar-based relative state estimator which achieves highly accurate,real-time trajectory estimation of multiple Unmanned Aerial Vehicles(UAVs)in GPS-denied envi... In this paper,we present a distributed framework for the lidar-based relative state estimator which achieves highly accurate,real-time trajectory estimation of multiple Unmanned Aerial Vehicles(UAVs)in GPS-denied environments.The system builds atop a factor graph,and only on-board sensors and computing power are utilized.Benefiting from the keyframe strategy,each UAV performs relative state estimation individually and broadcasts very partial information without exchanging raw data.The complete system runs in real-time and is evaluated with three experiments in different environments.Experimental results show that the proposed distributed approach offers comparable performance with a centralized method in terms of accuracy and real-time performance.The flight test demonstrates that the proposed relative state estimation framework is able to be used for aggressive flights over 5 m/s. 展开更多
关键词 Distributed relative state estimation GPS-denied environments Lidar-based perception Multi-UAV system Pose-graph optimization
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Enhancing the photocatalytic activity and photostability of zinc oxide nanorod arrays via graphitic carbon mediation 认领 引用 被引量：7
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作者 Xuewei Zhang Xueliang Zhang +3 位作者 Xin Wang Lequan Liu Jinhua Ye Defa Wang 《Chinese Journal of Catalysis》 SCIE EI CAS CSCD 北大核心 2018年第5期973-981,共9页
Low optical absorption and photocorrosion are two crucial issues limiting the practical applications of zinc oxide(ZnO)-based photocatalysts.In this paper,we report the fabrication of graphitic-carbon-mediated ZnO nan... Low optical absorption and photocorrosion are two crucial issues limiting the practical applications of zinc oxide(ZnO)-based photocatalysts.In this paper,we report the fabrication of graphitic-carbon-mediated ZnO nanorod arrays(NRAs)with enhanced photocatalytic activity and photostability for CO2 reduction under visible light irradiation.ZnO NRA/C-x(x=005,01,02,and 03)nanohybrids are prepared by calcining pre-synthesized ZnO NRAs with different amounts of glucose(0.05,0.1,0.2,and 0.3 g)as a carbon source via a hydrothermal method.X-ray photoelectron spectroscopy reveals that the obtained ZnO NRA/C-x nanohybrids are imparted with the effects of both carbon doping and carbon coating,as evidenced by the detected C-O-Zn bond and the C-C,C-O and C=O bonds,respectively.While the basic structure of ZnO remains unchanged,the UV-Vis absorption spectra show increased absorbance owing to the carbon doping effect in the ZnO NRA/C-x nanohybrids.The photoluminescence(PL)intensities of ZnO NRA/C-x nanohybrids are lower than that of bare ZnO NRA,indicating that the graphitic carbon layer coated on the surface of the ZnO NRA significantly enhances the charge carrier separation and transport,which in turn enhances the photoelectrochemical property and photocatalytic activity of the ZnO NRA/C-x nanohybrids for CO2 reduction.More importantly,a long-term reaction of photocatalytic CO2 reduction demonstrates that the photostability of ZnO NRA/C-x nanohybrids is significantly increased in comparison with the bare ZnO NRA. 展开更多
关键词 Photocatalysis ZnO nanorod array Graphitic carbon Charge transfer Photostability CO2 reduction
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Boronic acid-containing carbon dots array for sensitive identification of glycoproteins and cancer cells 认领 引用 被引量：2
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作者 Shuai Chen Xuewei Zhang +1 位作者 Yongliang Yu Jianhua Wang 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第10期3043-3047,共5页
Discrimination of glycoproteins and cell types is a significant but difficult issue.Herein,we presented a novel fluorescence sensor array for the detection and identification of glycoproteins and cancer cells based on... Discrimination of glycoproteins and cell types is a significant but difficult issue.Herein,we presented a novel fluorescence sensor array for the detection and identification of glycoproteins and cancer cells based on the specific affinity between boronic acid-containing carbon dots(BA-CDs)and cis-diol residues of polysaccharides.The differential binding affinity of three BA-CDs to various glycoproteins resulted in a different fluorescence turn-on signal pattern caused by aggregation-enhanced emission(AEE),along with negligible response from other proteins.Therefore,BA-CDs encompassing sensing elements and signal indicator into one can enable a fast and accurate discrimination of glycoproteins with simple and easy operation.Seven glycoproteins could be well discriminated at a very low concentration of 10 nmol/L.The discriminating capability of glycoproteins is not sacrificed in both human urine and serum.Notably,different glycoprotein compositions of cancer cells provide more recognizable features for identification of cancer cells,comparing to the total protein.Five cell types could be identified in 15 min at a low concentration of 1000 cells/mL.This method is fast,accurate,and easy operation,and has a potential application in cancer diagnosis. 展开更多
关键词 Sensor array Boronic acid Carbon dots Glycoproteins and cells Aggregation-enhanced emission
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Brasenia-inspired hydrogel with sustained and sequential release of BMP and WNT activators for improved bone regeneration 认领 引用 被引量：1
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作者 Xinqing Hao Xuewei Zhang +13 位作者 Yue Hu Chunxia Ren Cangwei Liu Lu Wang Yijun Zhou Shuangshuang Wang Huanyu Luo Guangxing Yan Xiao Wang Xiaomeng Wang Feilong Ren Ce Shi, Wenlong Song Hongchen Sun 《Chinese Chemical Letters》 SCIE CAS CSCD 2023年第7期162-168,共7页
Although bone morphogenetic protein(BMP) and WNT signaling play pivotal roles in bone development,homeostasis, and regeneration, the applications of proteins to stimulate corresponding signaling pathways showed limite... Although bone morphogenetic protein(BMP) and WNT signaling play pivotal roles in bone development,homeostasis, and regeneration, the applications of proteins to stimulate corresponding signaling pathways showed limited outcomes in the repair and regeneration of bone defects that might be attributed to the reciprocal interventions of these pathways. In order to satisfy the combinational and sequential activation of BMP and WNT pathways, inspired by the heterogeneous hydrogel-liked structures of Brasenia, heterogeneous alginate/chitosan hydrogels were fabricated and spatially loaded with FK506 and BIO to achieve sustained and sequential release of the activators. Alkaline phosphatase staining, alizarin red staining and q RT-PCR results suggested that FK506 and BIO enhanced osteoblastic differentiation in vitro when used separately. Besides, by mixing and matching the activators and the hydrogel layers, a superior releasing mode that a combination of early FK506 release and following BIO release was identified via both in vitro and in vivo explorations for most efficient bone regeneration. These results suggested that drug-loaded heterogeneous hydrogels possess great potentials in treating bone loss defects for future clinical practice. 展开更多
关键词 Bone regeneration FK506 BIO Heterogeneous hydrogels Osteogenic differentiation
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二元和三元后备母猪批次化生产技术应用效果分析 认领 引用 被引量：3
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作者 郭雅欣 张学炜 +4 位作者 郑梓 李宁 穆淑琴 李千军 崔茂盛 《猪业科学》 2020年第4期50-52,共3页
本试验于2018年5~10月在天津某猪场对二元(长×大)和三元(杜×长×大)后备母猪应用批次化生产技术后的静立率、淘汰率、妊娠率和窝产仔数等繁殖力指标进行了统计分析。试验分为常温(5—7月)和高温(8—10月)两个阶段,每批参... 本试验于2018年5~10月在天津某猪场对二元(长×大)和三元(杜×长×大)后备母猪应用批次化生产技术后的静立率、淘汰率、妊娠率和窝产仔数等繁殖力指标进行了统计分析。试验分为常温(5—7月)和高温(8—10月)两个阶段,每批参与试验的二元和三元母猪均大于30头。结果表明:在常温季节,三元后备母猪在静立率、妊娠率和总体妊娠率等方面与二元后备母猪无显著性差异(P>0.05);而在高温季节,三元后备母猪的静立率、妊娠率和总体妊娠率等方面均显著低于二元后备母猪(P<0.05)。相对于常温季节,高温季节里二元和三元母猪的妊娠率和总体妊娠率均显著降低,但在静立率方面只有三元母猪显著降低(P<0.05)。不论是在高温季节还是在常温季节,三元后备母猪的窝产仔数和窝均产仔数均显著低于二元后备母猪,而淘汰率却显著高于二元后备母猪(P<0.05)。结论:在常温季节,三元母猪静立率和妊娠率均与二元母猪差异不显著;但在高温季节三元母猪静立率和妊娠率均显著低于二元母猪;不论是高温还是常温季节,三元母猪的窝产仔数都显著低于二元母猪,而淘汰率显著高于二元母猪。 展开更多
关键词 批次化生产 季节 三元母猪 二元母猪 繁殖力
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在4℃降温平衡过程中0.2g/L咖啡因与精子共孵育时间对猪颗粒冻精质量的影响 认领 引用 被引量：1
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作者 郭雅欣 张学炜 +5 位作者 郑梓 李宁 陈亮 穆淑琴 李千军 崔茂盛 《猪业科学》 2020年第6期54-57,共4页
实验旨在探讨在猪精液于4℃平衡2 h过程中0.2 g/L咖啡因与精液共孵育2 h、1 h和0.5 h,对颗粒冻精解冻后精子活率、活力、质膜完整性和顶体完整性以及解冻后精子体外存活时间等指标的影响,以期进一步提高猪颗粒冻精质量。实验结果表明,... 实验旨在探讨在猪精液于4℃平衡2 h过程中0.2 g/L咖啡因与精液共孵育2 h、1 h和0.5 h,对颗粒冻精解冻后精子活率、活力、质膜完整性和顶体完整性以及解冻后精子体外存活时间等指标的影响,以期进一步提高猪颗粒冻精质量。实验结果表明,在精液冷冻之前,咖啡因不同平衡时间组的精子活率和活力都呈现出升高趋势,但与对照组差异不显著;咖啡因与精液共孵育2 h、1 h和0.5 h组的精子顶体完整率和质膜完整率显著低于对照组,前3组之间差异均不显著。而颗粒冻精解冻后,咖啡因与精液共孵育2 h、1 h和0.5 h组精子活率和活力均显著高于对照组,其中共孵育1 h组显著高于其他3组(P0.05);共孵育2 h组精子顶体完整率和质膜完整率显著低于对照组和共孵育0.5 h、1 h组(P<0.05),但后3组之间差异不显著;共孵育2 h组精子存活时间显著低于对照组、共孵育1 h和0.5 h组(P<0.05),其中共孵育1 h组精子存活时间最长,达7 d以上。总之,在精液4℃降温平衡过程中咖啡因与精液共孵育1 h对冷冻后精子质量最有利,解冻后精子活率和活力显著高于其他各组,且解冻后精子体外存活时间最长。 展开更多
关键词 颗粒冻精 咖啡因 共孵育时间 精液 公猪
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Non-Hermitian non-Abelian lattice gauge fields in electrical circuits 认领 引用
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作者 Chaohua Wu Xuewei Zhang +2 位作者 Zhenxing Cui Mou Yan Gang Chen 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CSCD 2026年第7期149-156,共8页
Non-Hermitian non-Abelian lattice gauge fields exhibit noncommutative and nonunitary gauge structures,giving rise to novel geometric and topological phenomena.However,their experimental realization has remained elusiv... Non-Hermitian non-Abelian lattice gauge fields exhibit noncommutative and nonunitary gauge structures,giving rise to novel geometric and topological phenomena.However,their experimental realization has remained elusive.Here,we implement a synthetic nonreciprocal SU(2)gauge field in a one-dimensional spinful chain by employing electric circuit networks with highly tunable asymmetric couplings.We observe a non-Hermitian non-Abelian Aharonov-Bohm effect in a single plaquette,where the final states exhibit an uncorrelated response under non-conjugated loop operations.Furthermore,we reveal the high-order nontrivial braiding and spin-hybridized unidirectional and bidirectional skin states,which are distinctive features of non-Hermitian non-Abelian lattice gauge fields.Our work paves the way for exploring rich non-Abelian phenomena in open systems and offers a versatile platform to implement exotic synthetic gauge fields. 展开更多
关键词 non-Hermitian skin effect non-Abelian gauge fields Aharonov-Bohm effect
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TLRs在肿瘤免疫中作用的研究进展 认领 引用
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作者 崔元峰 张雪伟 +1 位作者 袁东亚 张敏 《西藏医药》 2018年第2期84-87,共4页
Toll样受体(Toll-like receptors,TLRs)是固有免疫系统的主要组成部分,其主要功能是识别病原体的固有分子结构(pathogen-associated molecular,PAMPs;病原体相关分子模式)。TLRs存在于不同的细胞中,从上皮细胞到免疫活性细胞都能发现TLR... Toll样受体(Toll-like receptors,TLRs)是固有免疫系统的主要组成部分,其主要功能是识别病原体的固有分子结构(pathogen-associated molecular,PAMPs;病原体相关分子模式)。TLRs存在于不同的细胞中,从上皮细胞到免疫活性细胞都能发现TLRs的存在。目前认为,TLRs作用机制是结合一些衔接蛋白表达并触发下游激酶激活,从而导致主要促炎症介质反应发生。TLRs通过此作用机制能诱导固有免疫应答(提高细胞凋亡蛋白、促炎症因子和抗菌蛋白的表达)和适应性免疫应答(树突状细胞的成熟、抗原提呈等)的激活由于TLRs能够提高一个有机组织的特异性和非特异性反应,TLRs激动剂被广泛用于感染疾病的治疗中,同时在肿瘤中起到了免疫监视作用。然而,到目前为止,TLRs在肿瘤的进展中还可以有另外一些作用:一方面,TLRs配体可以抑制肿瘤细胞的增长;另一方面TLRs激动剂又可以促进恶性细胞的生存以及增加它们对化疗的抵抗作用。此综述将就TLRs在肿瘤免疫中的作用机制的研究情况作一简介。 展开更多
关键词 TLRs 肿瘤 固有免疫
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Achieving Intrinsic Luminescence of Pure Organic Monoand Di-Radicals in Aggregated States 认领 引用 被引量：1
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作者 Jiahao Guan Zihao Zhu +7 位作者 Quanquan Gou Jingmin Wang Zhiyuan Kuang Lintao Zhang Xuewei Zhang Xin Ai Alim Abdurahman Qiming Peng 《Aggregate》 EI CAS CSCD 2025年第9期148-156,共9页
Organic luminescent radicals are promising for optoelectronic applications,yet their practical implementation remains hindered by aggregation-caused quenching(ACQ)in aggregated states.In this study,we present a molecu... Organic luminescent radicals are promising for optoelectronic applications,yet their practical implementation remains hindered by aggregation-caused quenching(ACQ)in aggregated states.In this study,we present a molecular design strategy that enables unprecedented intrinsic luminescence from pure radicals across multiple aggregated states,including crystalline states,powders,and amorphous films,through the incorporation of sterically demanding TPP(2,4,6-triisopropylphenyl)groups.Comprehensive photophysical characterization coupled with structural analysis reveals that the TPP moieties effectively suppress detrimental intermolecular interactions,particularly exchange coupling andπ–πstacking between radical centers.The luminescent properties were analyzed via systematic theoretical calculations.The universality of this design principle is further demonstrated through its successful application to diradical systems,including Chichibabin’s and Muller’s hydrocarbons,which exhibit significantly enhanced emission in aggregated states.This work establishes a generalizable strategy for designing stable and efficient luminescent radicals in aggregated states,opening new avenues for radical-based optoelectronic devices. 展开更多
关键词 aggregated states diradicals intrisic luminescence organic luminescent radicals
Ion-selective polypyrrole coating enhances H2V3O8 cathode stability in aqueous zinc-ion batteries 认领 引用
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作者 Zeshen Deng Xuewei Zhang +5 位作者 Xuemei Sun Abdelaziz M.Aboraia Hongwen Li Lichun Yang Yuping Wu Min Zhu 《Science China Materials》 SCIE EI CAS CSCD 2025年第6期1929-1936,共8页
Aqueous zinc-ion batteries have emerged as promising candidates for large-scale energy storage.Despite its potential as a cathode material for AZIBs,H2V3O8 suffers from poor electrical conductivity,vanadium d... Aqueous zinc-ion batteries have emerged as promising candidates for large-scale energy storage.Despite its potential as a cathode material for AZIBs,H2V3O8 suffers from poor electrical conductivity,vanadium dissolution,and structural instability,which severely compromises its rate performance and cycling stability.To address these limitations,we have developed a polypyrrole-coated H2V3O8 composite(H2V3O8@Ppy).Density functional theory calculations demonstrate that Ppy exhibits substantially stronger interactions with HVO3(−1.97 eV)compared to hydrated Zn2+ ions(−0.205 eV).This selective interaction enables the Ppy coating to effectively capture dissolved HVO3 species while maintaining efficient transport of solvated Zn2+ion clusters,thereby preventing structural degradation of the cathode.The optimized H2V3O8@Ppy cathode delivers an impressive initial capacity of 405 mA h g-1 at 100 mA g-1 and demonstrates exceptional cycling stability,maintaining nearly 100%capacity retention after 800 cycles at 2 A g−1.Furthermore,a quasisolid-state zinc-ion battery incorporating H2V3O8@Ppy cathode exhibits excellent mechanical flexibility and superior longterm cycling performance.Notably,in situ XRD analysis reveals for the first time a two-step phase transformation mechanism of H2V3O8 during discharge/charge processes.This study presents an effective strategy for enhancing the structural stability of H2V3O8 cathodes in aqueous zinc-ion batteries. 展开更多
关键词 aqueous zinc-ion battery polypyrrole H2V3O8nanobelt surface coating ion-selective transport
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Expression characteristics,immune signatures,and prognostic value of the KIF family members identified across cancers 认领 引用
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作者 Xuewei Zhang Yawei Zhang +1 位作者 Guoxing Zheng Ronghua Yang 《Journal of Cancer Metastasis and Treatment》 2025年第1期145-160,共16页
Aim:The overexpression of Kinesin superfamily proteins(KIFs)has been increasingly recognized as a critical factor associated with unfavorable prognostic outcomes across a spectrum of cancers.This study aims to elucida... Aim:The overexpression of Kinesin superfamily proteins(KIFs)has been increasingly recognized as a critical factor associated with unfavorable prognostic outcomes across a spectrum of cancers.This study aims to elucidate the multifaceted role of KIFs within the tumor immune microenvironment and explore their potential as targets for precision cancer therapy.Methods:Utilizing comprehensive genomic datasets from the Cancer Genome Atlas and Genotype-Tissue Expression databases,we systematically analyzed KIF expression patterns and their potential oncogenic functions.To investigate the functional impact of KIF3A in hepatocellular carcinoma(HCC),we synthesized siKIF3A and transfected it into HepG2 cells,followed by a series of functional assays.Cell proliferation was meticulously evaluated using EdU incorporation,CCK8,and colony formation assays,while cell migration was assessed through scratch wound healing and Transwell migration assays.Quantitative analysis of gene and protein expression levels was performed using RT-PCR and Western blot techniques,respectively.Results:Our findings reveal that KIFs exhibit remarkably high mutation frequencies across multiple cancer types.Furthermore,we identified significant genomic and epigenetic modifications of KIFs in various tumors,with specific oncogenic mutations in certain cancers potentially serving as regulatory mechanisms for KIFs expression.Notably,tumor-derived KIFs demonstrate a strong association with immune cell infiltration patterns,suggesting their potential as novel therapeutic targets in cancer immunotherapy.Importantly,the majority of KIF family genes show significant correlations with patient prognosis,underscoring their clinical relevance.Specifically,KIF3A emerges as a promising prognostic marker for HCC,demonstrating significantly higher expression levels in HCC tissues compared to adjacent non-cancerous tissues(P<0.05).This overexpression strongly correlates with poor survival outcomes and established risk factors.Functional studies reveal that knockdown of KIF3A significantly inhibits the proliferation and migration capabilities of HCC cells(P<0.05),highlighting its critical role in tumor progression.Our findings suggest that KIF3A not only serves as a valuable prognostic biomarker but also represents a potential therapeutic target for HCC patients,particularly through its involvement in tumor immune regulation mechanisms.Conclusion:This comprehensive study provides novel insights into the role of KIFs,particularly KIF3A,in cancer biology and offers promising avenues for the development of targeted therapies in hepatocellular carcinoma.The integration of genomic analysis with functional validation underscores the potential of KIFs as both diagnostic markers and therapeutic targets in cancer management. 展开更多
关键词 KIFs pan-cancer hepatocellular carcinoma immunoinfiltration proliferation migration
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