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Developing river ethics:Advancing the understanding of water governance principles and promoting the modernization of water governance systems and capabilities 认领 引用 被引量：1
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作者 Yunchang Zhang Bo Liu +2 位作者 Yang Ding Jinyong Zhao Chang Li 《River》 EI CSCD 2025年第1期21-28,共8页
River ethics,a significant advancement inspired by Chinese President XI Jinping's ecological civilization thought,embodies the philosophical essence of river governance and represents a legacy of innovation by gen... River ethics,a significant advancement inspired by Chinese President XI Jinping's ecological civilization thought,embodies the philosophical essence of river governance and represents a legacy of innovation by generations of water resources professionals.Rooted in river ecology,it offers a framework for advancing modern water governance systems and capabilities.This paper examines eight dimensions of river ethics to provide actionable recommendations:enhancing knowledge systems on water,rivers,and lakes;addressing critical challenges in water governance to strengthen the foundational role of water authorities in ensuring water security,resource management,ecological sustainability and environmental protection;optimizing water project planning to mitigate ecological impacts;ensuring high standards in the lifecycle management of water projects;refining water diversion strategies for precise scheduling;utilizing ecosystem complexity for river and lake restoration;implementing tiered management of water-related disasters;and driving reforms to modernize water governance systems and mechanisms. 展开更多
关键词 ecosystem restoration high-quality development of water systems river ecology river ethics water governance
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Centrifuge modeling study on near-ground explosions and the coupling of ground shock energy in sandy foundation 认领 引用
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作者 Longhua Guan Zheng Pang +3 位作者 Qiang Lu Yang Ding Yubing Wang Yunmin Chen 《Defence Technology（防务技术）》 SCIE EI CAS CSCD 2026年第7期93-109,共17页
Blast effects and energy transfer in near-ground explosions differ significantly from underground scenarios,particularly in terms of ground shock propagation and energy coupling mechanisms across various geological co... Blast effects and energy transfer in near-ground explosions differ significantly from underground scenarios,particularly in terms of ground shock propagation and energy coupling mechanisms across various geological conditions.This study employs centrifuge modeling to simulate near-ground explosions in sandy soil,including surface explosions and airbursts.The focus was on blast-induced cratering,ground shock effects,and energy coupling in sandy foundations.Scaling laws for crater dimensions and ground shock parameters were established and validated based on experimental results.The"modeling of models"series showed good consistency in crater measurements,leading to an empirical formula for estimating crater radius in dry sand.For surface explosions,soil acceleration responses showed single peaks in the central zone(horizontal standoff distance<0.6 m/(kg)1/3)and dual peaks in the near-surface zone(0.79-1.2 m/(kg)1/3)due to combined effects of direct and airburst-induced ground shock.Empirical methods were developed to predict peak acceleration distributions in sandy foundations.Utilizing crater measurements and ground shock propagation laws,a computational approach for evaluating energy transmission in soil foundations was proposed.The study also developed prediction curves for ground shock energy coupling coefficients with scaled blast depth/height,providing a unified model for both underground and near-ground explosions in sandy foundations.The research findings can enhance the methodologies for simulating blast effects and offer a scientific basis for optimizing weapon effectiveness and protective engineering design. 展开更多
关键词 Centrifuge model tests Near-ground explosions Explosion-induced cratering Ground shock Energy coupling
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Pressure calibrations of high-pressure large-volume presses at HPSTAR 认领 引用
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作者 Yongjiang Xu Peiyan Wu +17 位作者 Sheng Shang Xue Wang Taihang Li Shuchang Gao Shijie Lv Hang Cheng Qianzhi Xu Shang Lei Jiajia Feng Lei Zhao Wim van Westrenen Takayuki Ishii Bin Chen Lei Su Yang Ding Wenge Yang Ho-Kwang Mao Yanhao Lin 《Matter and Radiation at Extremes》 SCIE EI CAS CSCD 2026年第1期111-130,共20页
Large-volume presses(LVPs)are widely utilized in diverse research fields—including high-pressure physics,chemistry,materials science,and Earth and planetary sciences—to investigate the physical and chemical properti... Large-volume presses(LVPs)are widely utilized in diverse research fields—including high-pressure physics,chemistry,materials science,and Earth and planetary sciences—to investigate the physical and chemical properties of materials under extreme high-pressure and hightemperature conditions.A prerequisite for achieving reproducible property measurements is the determination and control of pressure within experimental setups.However,the lack of precise pressure calibration in LVPs hinders the broader application of such devices in ultrahigh-pressure studies.This study employs a suite of standard phase transition-based pressure markers—comprising metallic conductors,semiconductors,and minerals—through both in situ and ex situ identification approaches,to establish pressure calibration curves ranging from 0.4 to>30 GPa for various types of LVP installed at the Center for High Pressure Science and Technology Advanced Research(HPSTAR),Beijing,including piston–cylinder,cubic,and multi-anvil presses.The results provide a unified and traceable pressure reference for highpressure experiments conducted at HPSTAR,while also offering technical guidance and calibration standards for other researchers utilizing similar LVP systems,thereby enabling more consistent comparison between different laboratories.This work facilitates the advancement of LVP research toward broader applications in higher-pressure regimes. 展开更多
关键词 chemistry earth planetary sciences pressure calibration high pressure physics materials science investigate physical chemical properties materials determination control pressure
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Advanced photocatalysts for synergistic pollutant elimination and clean energy evolution 认领 引用
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作者 Yang Ding Zhixue Li +4 位作者 Shuzeng Zhang Runtian Zheng Hongyan Li Chunhua Wang Heng Zhao 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第5期875-892,I0021,共18页
Developing sustainable and green approaches to address the severe energy crisis and environmental pollution problems has emerged as a research hotspot over the past few decades.Photocatalytic technology,which harnesse... Developing sustainable and green approaches to address the severe energy crisis and environmental pollution problems has emerged as a research hotspot over the past few decades.Photocatalytic technology,which harnesses solar energy as a clean energy and renewable power source to drive chemical reactions,offers a highly promising platform for the simultaneous degradation of organic pollutants and the generation of sustainable energy carriers.This review systematically summarizes the recent progress on photocatalytic synergistic systems for organic pollutant elimination(dyes,antibiotics,volatile organic compounds(VOCs),etc.)and sustainable energy evolution(H2,H2O2,CH4,etc.).Firstly,the fundamental principles and mechanisms of photocatalytic synergy reactions are elucidated,with emphasis on coupling strategies that integrate energy conversion pathways with pollutant oxidation processes.Secondly,various modification strategies developed to enhance photocatalytic efficiency are detailed,including heterojunction construction,ion doping,single-atom loading,defect engineering,and framework design.Subsequently,different types of photocatalytic synergistic systems coupling organic degradation with chemical fuel generation are outlined and discussed,highlighting their design principles,structural advantages,and catalytic performance.Finally,the current challenges in this field are critically analyzed,along with the proposed future development directions,including advanced material design,system optimization,and pathways toward scalable practical applications. 展开更多
关键词 Synergistic photocatalysis Pollutants degradation Energy crisis Sustainable energy production Catalysis mechanism
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Phonon bottleneck effect due to finite shrinking gap revealed by high-pressure ultrafast dynamics 认领 引用
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作者 Yanling Wu Q.Wu +9 位作者 X.Yin Y.X.Huang Takeshi Nakagawa Z.Y.Tian Fei Sun Q.M.Zhang Jun Chang Ho-kwang Mao Yang Ding Jimin Zhao 《Chinese Physics B》 SCIE EI CAS CSCD 2026年第3期137-142,共6页
High-pressure ultrafast dynamics has been recently developed,enabling the exploration of non-equilibrium properties of various quantum materials under high pressure.Particularly,by investigating the pressure dependenc... High-pressure ultrafast dynamics has been recently developed,enabling the exploration of non-equilibrium properties of various quantum materials under high pressure.Particularly,by investigating the pressure dependence of time-resolved ultrafast dynamics,we have discovered a pressure-induced phonon bottleneck effect(PBE).To date,all reported PBEs are due to fully closed gaps,which was reflected in the simultaneous characteristic changes in both amplitude and lifetime of the phonon-phonon scattering slow relaxation component.However,as reflected through its connection to Euler disk,incompletely closed gaps can also induce PBEs.In this work,we report the first PBE due to a finite shrinking gap.As is known,it is challenging to directly observe high-pressure-induced variations in electronic band gaps due to the diamond anvil cell.Here,by investigating Sr2IrO4in our previous work,we obtain an empirical formula for the pressure-induced energy gap variation at room temperature.Our quantitative analysis shows that the gap is finite shrinking rather than fully closed. 展开更多
关键词 phonon bottleneck effect ultrafast dynamics high pressure ultrafast spectroscopy finite gap
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Slow photons effect amplifying photo/photothermocatalytic solar fuel production 认领 引用
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作者 Yang Ding Shuzeng Zhang +4 位作者 Zhixue Li Guoxiang Yang Runtian Zheng Ning Han Chunhua Wang 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第3期140-153,共14页
Transforming sunlight into renewable energy sources like hydrogen and methane through photocatalytic water splitting and the CO2conversion presents a promising prospect to tackle energy scarcity and environmental p... Transforming sunlight into renewable energy sources like hydrogen and methane through photocatalytic water splitting and the CO2conversion presents a promising prospect to tackle energy scarcity and environmental pollution caused by burning fossil fuels.As the core of the photocatalytic technique,photocatalysts design is most significant for acquiring the desirable catalytic performance and target products.Photonic crystals,also denoted as inverse opals and three-dimensionally ordered macroporous materials(3DOM),have been extensively applied in photocatalytic fields due to their distinct advantages.Specifically,photonic crystal possesses slow photons effect,rich reactive sites,and well-interconnected inner channels.Among the above advantages,the slow photons effect contributes the most essential role for accelerating photocatalytic reaction.However,how to design materials with maximized slow photons effect upon specific wavelength illumination is still in the infancy.Although some reviews about 3DOM photocatalysts have been published,a critical review focusing on tunable slow photons effects for efficient photocatalysis is still lacking.In this review,we highlighted recent advances in slow photons effect in boosting solar energy conversion.Meanwhile,the relevant mechanism and fundamentals of the slow photons effect are discussed.Finally,we present our vision of the future developments and challenges in this exciting research field. 展开更多
关键词 Slow photon effect Photonic crystal CO2conversion Water splitting Solar fuel production
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Nose-to-brain delivery of donepezil within a small dose improves bioavailability and efficacy for Alzheimer’s disease treatment 认领 引用
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作者 Gang Wang Xuezhe Duan +3 位作者 Defang Ouyang Jianping Zhou Huaqing Zhang Yang Ding 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS CSCD 2026年第2期194-208,共15页
Oral administration of donepezil(Don)is the first-line medication for Alzheimer’s disease(AD);however,the dysphagia of elderly patients and severe gastrointestinal side effects substantially restrict administration c... Oral administration of donepezil(Don)is the first-line medication for Alzheimer’s disease(AD);however,the dysphagia of elderly patients and severe gastrointestinal side effects substantially restrict administration compliance.Herein,we exploit a nose-tobrain pathway for Don administration to obtain smaller dosage but higher intracerebral bioavailability(BA),thereby achieving inhibition of acetylcholinesterase(AChE)activity and avoiding side effects.With respect to the intranasal administration design,a patientfriendly Don nasal spray without preservatives was developed.The administration of Don nasal spray demonstrated good nasal deposition and mucosa permeation ability comparable to that of the model drug propranolol.The mice intranasally administered Don at an equivalent oral dose(0.65 mg/kg)demonstrated rapid brain distribution(∼5 min)and long-lasting AChE inhibition effects(72 h).To obtain the optimal intranasal dose,a dosedescending study was conducted by cascading the oral dosage at a 1:3 ratio.The results demonstrated that intranasal administration of Don at 0.07 mg/kg resulted in intracerebral BA and AChE inhibition comparable to oral administration at 0.65 mg/kg,suggesting an 89%dose reduction.Compared with oral administration,anti-AD effectiveness was evaluated in AD model mice after 34-d-intranasal administration of Don,resulting in a shorter onset time,higher intracerebral drug concentration,and a longer duration of AChE inhibition(0.07 mg/kg).The nasal and systemic safety of intranasal administration of Don was confirmed in an allergic rhinitis mouse model after 4 weeks of intranasal administration.Thus,a small dose of Don exhibits improved intracerebral BA and AChE inhibition via intranasal administration,thereby offering better compliance and reducing side effects in AD treatment. 展开更多
关键词 Alzheimer’s disease Intranasal administration Small-dose donepezil Acetylcholinesterase inhibition Side effect prevention
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Boosting photovoltaic efficiency via efficient passive cooling from all-natural hydrogels with robust interfacial adhesion 认领 引用
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作者 Yang Ding Xianrong Huang +6 位作者 Yang Hu Xiangyu Zhao Gangchen Lu Cheng Zhou Shilong Liu Xiang Lu Jinping Qu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第3期206-216,共11页
The operational temperature rise of photovoltaic(PV)panels reduces their power generation efficiency and shortens their lifespan.Hygroscopic hydrogel-based evaporative cooling technology provides a promising solution ... The operational temperature rise of photovoltaic(PV)panels reduces their power generation efficiency and shortens their lifespan.Hygroscopic hydrogel-based evaporative cooling technology provides a promising solution for PV cooling due to high-enthalpy water evaporation.However,current hydrogels remain plagued by cooling interface mismatch and environmental concerns,which limit their practical implementation.Herein,a“green”and self-adhesive hygroscopic hydrogel consisting only of cheap lotus root powder and LiCl is designed,which can form robust interfacial adhesion with PV panels for efficient and durable cooling.Leveraging its compelling hygroscopicity,the hydrogel is able to rapidly capture moisture to recover cooling capacity,thus achieving self-sustained cooling.Besides,the“salting-in”effect brought by LiCl endows the hydrogel with notable softness and self-adhesiveness,which enables it to tightly combine with PV panels to optimize heat conduction and improve cooling efficiency.As a result,under 1.0 kW m-2illumination,a PV temperature drop of 18.2℃ and a cooling power of 358 W m-2were delivered by attaching the hydrogel to the rear of the PV panel,accompanied by a 7.7%improvement in energy efficiency.Overall,this self-sustained passive cooling strategy,activated by the all-natural hydrogel,sheds light on the development of PV thermal management. 展开更多
关键词 Evaporative cooling PV module thermal management Hygroscopic hydrogel Interfacial adhesion Thermal conduction
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Advances in deep learning for bacterial image segmentation in optical microscopy 认领 引用
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作者 Zhijun Tan Yang Ding +6 位作者 Huibin Ma Jintao Li Danrou Zheng Hua Bai Weini Xin Lin Li Bo Peng 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2026年第1期30-44,共15页
Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bac... Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions. 展开更多
关键词 Bacterial image deep learning optical microscopy image segmentation artificial intelligence
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Maternal individuality matters:Disentangling individual variation in regeneration contributions to guide precision conservation of endangered species 认领 引用
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作者 Yang Ding Yingqun Feng Bo Wang 《Forest Ecosystems》 SCIE CAS CSCD 2026年第3期740-746,共7页
Understanding the drivers of regeneration failure is essential for conserving endangered plant species.Tradi-tional conservation often overlooks individual variation within populations,potentially masking critical de-... Understanding the drivers of regeneration failure is essential for conserving endangered plant species.Tradi-tional conservation often overlooks individual variation within populations,potentially masking critical de-terminants of recruitment success.Here,we investigated the role of maternal reproductive variation in shaping regeneration potential in Pinus dabeshanensis,a critically endangered conifer endemic to central China.We focused on the seed-to-dispersal phase of regeneration,quantifying individual“regeneration contribution”as the product of successful dispersal rate and total mature seed production.Through three years of intensive moni-toring of 88 P.dabeshanensis adult trees,we documented extreme inter-individual variation in reproductive output:55 trees(62.5%)failed to produce any seeds during the three-year study period,while among the 33 reproductive individuals,seed production varied over 300-fold(38-11,195 seeds per tree),abortion rates ranged from 30%to 87%,and mature seed output differed by 1000-fold(5-5029 seeds).Remarkably,just six trees(7%of the population)contributed over 70%of all mature seeds.Using standardized ex situ seed dispersal experi-ments,we further examined how this variation influenced seed fate among the five most productive trees.Critically,these trees disproportionately influenced potential recruitment:the top producer contributed 113 successfully dispersed seeds,compared to only 44 and 45 from lower-yielding individuals.Our findings demonstrate that extreme reproductive skew among maternal trees,rather than population-wide seed predation or dispersal limitation,drives regeneration potential in this endangered species.This study establishes an individual-based framework for precision conservation,advocating for targeted management of high-yielding“dominant mother”trees to optimize resource allocation and enhance recovery of P.dabeshanensis and other endangered plants facing similar recruitment challenges. 展开更多
关键词 Endangered species Individual variation Maternal effects Pinus dabeshanensis Precision conservation Reproductive skew Seed dispersal
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Systematic identification and annotation of multiple-variant compound effects at transcription factor binding sites in human genome 认领 引用 被引量：1
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作者 Si-Jin Cheng Shuai Jiang +2 位作者 Fang-Yuan Shi Yang Ding Ge Gao 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2018年第7期373-379,共7页
Understanding the functional effects of genetic variants is crucial in modern genomics and genetics. Transcription factor binding sites （TFBSs） are one of the most important cis-regulatory elements. While multiple t... Understanding the functional effects of genetic variants is crucial in modern genomics and genetics. Transcription factor binding sites （TFBSs） are one of the most important cis-regulatory elements. While multiple tools have been developed to assess functional effects of genetic variants at TFBSs, they usually assume that each variant works in isolation and neglect the potential ＂interference＂ among multiple variants within the same TFBS. In this study, we presented COPE-TFBS （Context-Oriented Predictor for variant Effect on Transcription Factor Binding Site）, a novel method that considers sequence context to accurately predict variant effects on TFBSs. We systematically re-analyzed the sequencing data from both the 1000 Genomes Project and the Genotype-Tissue Expression （GTEx） Project via COPE-TFBS, and identified numbers of novel TFBSs, transformed TFBSs and discordantly annotated TFBSs resulting from multiple variants, further highlighting the necessity of sequence context in accurately annotating genetic variants. 展开更多
关键词 Compound effect Transcription factor binding site Variant annotation Bioinformatics Genetic variants
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安格斯母牛发情周期中瘤胃温度与蠕动次数的变化规律及监测适用性 认领 引用
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作者 刘理想 王文学 +14 位作者 田菁 李慧 王潇 赵濛 杨鼎 金露达 秦湉 崔欢 于浩天 苑维武 刘锋 王彩虹 赵云 李先龙 田如刚 《畜牧兽医学报》 CAS CSCD 北大核心 2026年第7期3790-3800,共11页
旨在解决肉牛规模化养殖中母牛发情监测准确率低、应激反应大等问题,明确瘤胃温度与瘤胃蠕动次数在发情周期的动态变化规律及监测适用性。本研究以66头4~6岁、3胎及以上健康安格斯经产母牛为试验对象;采用单组连续监测设计,以每头母牛... 旨在解决肉牛规模化养殖中母牛发情监测准确率低、应激反应大等问题,明确瘤胃温度与瘤胃蠕动次数在发情周期的动态变化规律及监测适用性。本研究以66头4~6岁、3胎及以上健康安格斯经产母牛为试验对象;采用单组连续监测设计,以每头母牛为独立重复,通过智能瘤胃传感器连续采集“发情前7 d—发情当天—发情次日”的瘤胃温度与瘤胃蠕动次数;结合“每2 h行为观察+直肠卵泡检查”双重标准判定发情,采用SPSS 21.0软件进行重复测量方差分析,GraphPad Prism 9.0绘图,P<0.05为差异显著。结果表明:①瘤胃温度与瘤胃蠕动次数均呈显著昼夜节律,瘤胃温度11:00达谷值((38.35±0.31)℃)、18:00达峰值((39.03±0.33)℃),瘤胃蠕动次数呈双峰值(10:00,(1761.91±1209.40)次·h-1、18:00,(2238.66±1291.05)次·h-1);②发情当天瘤胃温度均值((38.95±0.20)℃)较发情前7 d均值((38.69±0.02)℃)显著升高(0.26±0.02)℃(P<0.05),关键升温始于发情前2 h,发情后4~6 h达峰值((39.49±0.49)℃);发情当天的瘤胃蠕动次数((67579.70±11946.63)次)较发情前7 d((34800.20±9215.845)次)约增加93.08%(P<0.05),响应始于发情前10 h,发情后4~6 h达峰值((4063.67±1843.94)次·h-1)。综上,牛发情周期中瘤胃温度与瘤胃蠕动次数动态规律明确,具备低应激、高灵敏的发情监测优势,可作为肉牛规模化牧场中母牛精准发情监测的核心指标,为肉牛繁殖管理数智化升级提供数据支撑。 展开更多
关键词 安格斯母牛 发情周期 瘤胃温度 瘤胃蠕动次数 发情监测
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植保无人机温性荒漠草原防治新疆亮柔拟步甲三种药剂筛选 认领 引用
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作者 常峰华 杨鼎 +6 位作者 徐震霆 王志鹏 岳方正 李景浩 张誉文 柴守权 李娟 《草学》 2026年第3期55-61,共7页
在新疆温性荒漠草原中,亮柔拟步甲(Prosodes dilaticollis)作为主要地下危害害虫之一,但其相关防治研究较少,危害较为严重,为维护草原生态环境,探索高效、绿色、环保的防治亮柔拟步甲新途径至关重要。为筛选防治亮柔拟步甲的有效药剂,选... 在新疆温性荒漠草原中,亮柔拟步甲(Prosodes dilaticollis)作为主要地下危害害虫之一,但其相关防治研究较少,危害较为严重,为维护草原生态环境,探索高效、绿色、环保的防治亮柔拟步甲新途径至关重要。为筛选防治亮柔拟步甲的有效药剂,选用3种高效绿色生物源药剂,采用植保无人机低空喷施防治新疆亮柔拟步甲幼虫,比较不同用药量和用药天数的防治效果。结果表明:0.5%高效氯氰菊酯EC无人机防治亮柔拟步甲时,用药量为600mL/hm2、施药天数为15d或用药量为900 mL/hm2、施药天数为7d时,防治效果最佳为98.21%。用药量为900mL/hm2、施药天数为7d时,1.5%烟碱·苦参碱SL的防治效果最优为64.29%,可以作为防治新疆亮柔拟步甲发生危害较轻时常规防治的替代药剂,也可根据情况作为备选药剂。两者交替使用,旨在降低亮柔拟步甲的抗药性,提高害虫防治的综合效果和持久性。但本研究中1%蛇床子素水乳剂SL的最高防治效果为50.00%,防治效果一般,不推荐使用。 展开更多
关键词 新疆 亮柔拟步甲 高效氯氟氰菊酯 蛇床子素 苦参碱 田间防效
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辽宁省车前草真菌病害调查研究 认领 引用
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作者 常峰华 李景浩 +3 位作者 张誉文 杨鼎 徐震霆 岳方正 《辽宁林业科技》 2026年第1期9-14,共6页
车前草(Plantago asiatica)具有重要的生态价值、饲用价值和药用价值。2022年,采用样方法对辽宁省19个地区车前草真菌病害进行了调查,结果表明:共调查到白粉病、霜霉病、锈病和叶斑病4种真菌病害,总发病率为30.3%,病情指数为35.8,样方... 车前草(Plantago asiatica)具有重要的生态价值、饲用价值和药用价值。2022年,采用样方法对辽宁省19个地区车前草真菌病害进行了调查,结果表明:共调查到白粉病、霜霉病、锈病和叶斑病4种真菌病害,总发病率为30.3%,病情指数为35.8,样方平均发生面积为2090 m2。其中,发病程度最严重的是霜霉病,发病率为29.8%,病情指数为36.6;叶斑病的发病率为1.3%,病情指数为31.7;白粉病的发病率为0.3%,病情指数为46.3;锈病的发病率为0.3%,病情指数为21.4。此外,锈病只在一个地区发生;白粉病、叶斑病分别在3、5个地区发生;霜霉病发生地区最广,在17个地区发生。该项调查明确了辽宁省部分地区车前草主要真菌病害种类、发生情况,并针对不同病害防治提出了建议。 展开更多
关键词 辽宁省 车前草 霜霉病 发病率 病情指数
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Investigations of key issues on the reproducibility of high-Tc superconductivity emerging from compressed La3Ni2O7 认领 引用 被引量：6
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作者 Yazhou Zhou Jing Guo +12 位作者 Shu Cai Hualei Sun Chengyu Li Jinyu Zhao Pengyu Wang Jinyu Han Xintian Chen Yongjin Chen Qi Wu Yang Ding Tao Xiang Ho-kwang Mao Liling Sun 《Matter and Radiation at Extremes》 SCIE EI CAS CSCD 2025年第2期80-89,共10页
Signatures of superconductivity near 80 K have recently been discovered in single crystals of La3Ni2O7under pressure,which makes it a new candidate for high-temperature superconductors dominated by 3d transit... Signatures of superconductivity near 80 K have recently been discovered in single crystals of La3Ni2O7under pressure,which makes it a new candidate for high-temperature superconductors dominated by 3d transition elements,following the cuprate and iron-pnictide superconductors.However,there are several critical questions that have been perplexing the scientificommunity:(1)What factors contribute to the inconsistent reproducibility of the experimental results?(2)What is the fundamental nature of pressure-induced superconductivity:bulk or nonbulk(filamentary-like)(3)Where is the superconducting phase located within the sample if it is filamentary-like(4)Is the oxygen content important for the development and stabilization of superconductivity?In this study,we employ comprehensive high-pressure techniques to address these questions.Through our modulated ac susceptibility measurements,we are the firs to fin that the superconductivity in this nickelate is filamentary-like Our scanning transmission electron microscopy investigations suggest that the filamentary-lik superconductivity most likely emerges at the interface between La3Ni2O7and La4Ni3O10phases.By tuning the oxygen content of polycrystalline La3Ni2O7,we also fin that it plays vital role in the development and stabilization of superconductivity in this material.The upper and lower bounds on the oxygen content are 7.35 and 6.89,respectively.Our results provide not only new insights into the puzzling issues regarding this material,but also significan information that will enable a better understanding of its superconductivity. 展开更多
关键词 scanning transmission electron microscopy oxygen content reproducibility filamentary superconductivity nickelate high temperature superconductivity d transition elementsfollowing pressure induced superconductivity
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Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease 认领 引用 被引量：3
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作者 Guo-Lin Miao Wen-Xi Zhang +23 位作者 Yi-Tong Xu Yi-Ran Liu Ping-Ping Lai Jia-Bao Guo Gong-Lie Chen Jing-Xuan Chen Zi-Hao Zhou Yan-Wei Li Chong Zhang Yang Ding Lian-Xin Zhang Yu-Fei Han Jin-Xuan Chen Jing-Dong Wu Yin-Qi Zhao Si Mei Yang Zhao Yuan-Wu Ma Ling Zhang Wei Huang Dong-Yu Zhao Er-Dan Dong Yu-Hui Wang Xun-De Xian 《Military Medical Research》 SCIE CAS CSCD 2025年第9期1329-1349,共21页
Background:Kinesin family member 13B(KIF13B),a crucial motor protein,exerts multiple cellular biological functions.However,the implication of KIF13B in metabolic dysfunction-associated fatty liver disease(MAFLD)has no... Background:Kinesin family member 13B(KIF13B),a crucial motor protein,exerts multiple cellular biological functions.However,the implication of KIF13B in metabolic dysfunction-associated fatty liver disease(MAFLD)has not been explored yet.This study aimed to investigate KIF13B’s role and underlying mechanism in MAFLD and proposes it as a potential pharmacological target.Methods:We assessed KIF13B expression in MAFLD patients and rodent models.The roles of Kif13b in lipid metabolism and MAFLD were investigated using whole-body Kif13b knockout mice,hepatocyte-specific Kif13b-deficient mice and hamsters exposed to different diets.The underlying mechanisms by which Kif13bgoverned hepatic lipid homeostasis and MAFLD progression were explored in vitro.Finally,the Kif13b’s impact on atherosclerotic development was studied in the context of MAFLD.Results:KIF13B expression was reduced in patients and murine models with MAFLD.Rodents with global or liver-specific knockout of the Kif13b gene exhibit spontaneous hepatic steatosis,which is further exacerbated by different overnutrition diets.Overexpression of human KIF13B by lentivirus effectively prevented metabolic dysfunction-associated steatohepatitis(MASH)in methionine-choline-deficient diet(MCD)-fed mice.Furthermore,Kif13b deficiency accelerates atherosclerosis in the context of MAFLD.Mechanistically,Kif13b depletion increases hepatic lipid synthesis and impairs mitochondrial oxidative phosphorylation.Further screening reveals that Kif13b interacts with AMP-activated catalytic subunit alpha 1(AMPKα1)to regulate the phosphorylation of AMPKα1,governing mitochondrial homeostasis and suppressing sterol regulatory element binding protein 1(Srebp1)-mediated denovo lipogenesis in the liver.Conclusion:This work establishes a causal relationship between KIF13B deficiency and MAFLD,emphasizing KIF13B as a potential therapeutic target for treating MAFLD. 展开更多
关键词 Kinesin family member 13B(KIF13B) AMP-activated catalytic subunit alpha 1(AMPKα1) Mitochondrial homeostasis Lipid metabolism Metabolic dysfunction-associated fatty liver disease(MAFLD)
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Coupled transformations of manganese and dissolved organic matter molecules during iron(oxyhydr)oxide-catalyzed oxidation of Mn(Ⅱ) 认领 引用 被引量：1
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作者 Xixian Huang Bing Yang +1 位作者 Ye Dou Yang Ding 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2025年第9期538-551,共14页
The abiotic oxidation of divalentmanganese(Mn(Ⅱ))and the formation of Mn oxides are important geochemical processes,which control the mobility and availability of Mn as well as element cycling and pollutant behavior ... The abiotic oxidation of divalentmanganese(Mn(Ⅱ))and the formation of Mn oxides are important geochemical processes,which control the mobility and availability of Mn as well as element cycling and pollutant behavior in soils.It was found that iron(oxyhydr)oxides can catalyze Mn(Ⅱ)oxidation,but the effects of the coexisting dissolved organic matter(DOM)molecules on the catalysis of different iron(oxyhydr)oxides for Mn(Ⅱ)oxidation are poorly understood.Herein,we investigated Mn(Ⅱ)oxidation under the impacts of the interactions between iron(oxyhydr)oxides(i.e.,ferrihydrite,goethite and hematite)and DOM molecules.Simultaneously,we elucidated the variations of DOM composition and properties.Our results indicated that the catalysis of iron(oxyhydr)oxides for Mn(Ⅱ)oxidation was significantly inhibited by DOM.Moreover,DOM had less inhibiting effect on the catalysis of ferrihydrite for Mn(Ⅱ)oxidation and the formation of Mn oxides(e.g.,hausmannite and buserite)relative to goethite and hematite,whichwas partially because of the higher electron transfer capacities of ferrihydrite.Meanwhile,DOM molecules with high nominal oxidation state of carbon(NOSC),molecular weight,unsaturation and aromaticity were selectively adsorbed and oxidized by Mn oxides,including the oxygenated phenols and polyphenols.The newly formed molecules mainly belonged to phenols depleted of oxygen and aliphatics.Furthermore,NOSC was a key molecular characteristic for controlling DOM composition during DOM adsorption and oxidation by Mn oxides when iron minerals were present.Overall,our research contributes to understanding Mn(Ⅱ)oxidation mechanisms under heterogeneous systems and behaviors of DOM molecules in the environment. 展开更多
关键词 Mn(Ⅱ)oxidation Mn oxides Iron(oxyhydr)oxides Dissolved organic matter DOM oxidation
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CeO2 nanozyme-embedded thermal-deformative polymer for site-specific chemotherapy via HIF-1α-P-gp/lipolysis axis reversal 认领 引用
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作者 Zhiyuan Tang Yuening Sun +3 位作者 Quanhua Yi Qian Ding Yang Ding Jianfei Huang 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS CSCD 2025年第3期167-181,共15页
The effective intracellular accumulation of doxorubicin(DOX)is crucial for improving antitumor efficacy,which is severely impeded by limited drug penetration,uncontrollable drug release,and drug resistance.In this stu... The effective intracellular accumulation of doxorubicin(DOX)is crucial for improving antitumor efficacy,which is severely impeded by limited drug penetration,uncontrollable drug release,and drug resistance.In this study,a thermal-deformative polymer embedding ultrasmall ceria(CeO2)was rationally designed for deep tumor drug shuttling and hypoxia reversal to improve chemotherapy.Structurally,the CeO2nanozyme was covalently grafted with a polymer of p(NIPAM-co-AM)that could sharply shrink for DOX loading,which was consolidated with polydopamine(PDA)film encapsulation.Thereafter,a tumor penetration guide of apolipoprotein A-I(apoA-I)conjugated iRGD peptide(apoA-I-iRGD)was further decorated onto the PDA shell via Michael addition for preparing CeO2P/DOX@iAPDA.With the aid of apoA-I-iRGD,CeO2P/DOX@iAPDA penetrated both the tumor spheroids(∼78μm)and the tumors of the mouse model deeply.After internalization by tumor cells and triggering by low pH in lysosomes,rapid DOX release was achieved by peeling off the PDA shell and thermosensitive deformation of p(NIPAM-co-AM).CeO2P/DOX@iAPDA provided 66.4%tumor suppression in 4T1-derived tumor spheroids and 63.2%in 4T1-tumorbearing mice,respectively.Preliminary mechanistic research involving western blotting and immunohistochemistry revealed that CeO2P/DOX@iAPDA reversed resistance through the through HIF-1α-P-gp/lipid axis.Collectively,this study intelligently integrated CeO2nanozymes,temperature-sensitive polymers,and imitated biochemical modifications to improve chemotherapy for breast cancer. 展开更多
关键词 Biomimetic assembly Deep tumor penetration Rapid drug release Reversal of drug resistance Breast cancer chemotherapy Thermosensitive polymer
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Settlers'and nomads'insights into willingness to participate in national park construction:Implications of the theory of planned behavior 认领 引用
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作者 YANG Ding SONG Jinping +3 位作者 YANG Zhenshan CHEN Dongjun MA Ting SONG Chengzhen 《Journal of Geographical Sciences》 SCIE CSCD 2025年第12期2708-2730,共23页
Achieving conservation goals in natural habitats requires a balanced approach that integrates both sustainable community development and nature conservation,rather than completely excluding human activities from wilde... Achieving conservation goals in natural habitats requires a balanced approach that integrates both sustainable community development and nature conservation,rather than completely excluding human activities from wilderness areas.However,limited understanding exists regarding locals'willingness to participate(WTP)in the construction and stewardship of national parks as well as their driving factors behind this willingness.To identify the key drivers that promote locals'WTP in national parks,we investigated local residents'participation willingness and embedded an additional structure perceived value(PV)into the Theory of Planned Behavior(TPB)model,analyzing the data by using structural equation modeling.Local communities were slightly willing to participate in Changtang National Park and conservation in general;interestingly,nomads'willingness was stronger than settlers'.Perceived behavioral control(PBC)exhibited the most significant impact on WTP,with particular emphasis on the livelihood risks associated with grasslands.PV indirectly influenced WTP by affecting attitude(ATT),personal/social norms(PSN),and PBC,while it did not have a direct impact on WTP.For settlers and nomads,different variables influence their varying levels of willingness to engage in park participation.These results deepen our understanding of community willingness to participate and differences in drivers of WTP between settlers and nomads,contributing to relevant knowledge to inform seeking a balance between sustainable community development and nature conservation. 展开更多
关键词 willingness to participate perceived value personal/social norms Theory of Planned Behavior Changtang National Park candidate site
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空间碎片探测成像一体化变焦光学系统设计 认领 引用
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作者 刘瑞琪 李旭阳 +4 位作者 许彤裕 杨鼎 任志广 袁灏 候继云 《光子学报》 EI CAS CSCD 北大核心 2026年第6期48-61,共14页
针对传统空间观测载荷功能分离、硬件冗余度较高的问题,设计了一种“探测-成像”一体化共口径变焦光学系统。该架构通过离轴三反无焦前端与二次成像变焦结构的深度融合,实现了跨尺度观测任务的灵活切换:在短焦大视场模式下,系统利用高... 针对传统空间观测载荷功能分离、硬件冗余度较高的问题,设计了一种“探测-成像”一体化共口径变焦光学系统。该架构通过离轴三反无焦前端与二次成像变焦结构的深度融合,实现了跨尺度观测任务的灵活切换:在短焦大视场模式下,系统利用高灵敏度光学链路实现对16 Mv暗弱碎片目标的广域搜索;在长焦窄视场模式下,通过提升角分辨率获取目标的精细形态与物理特征。系统在2300~4600 mm变焦行程内,视场角由1.19°连续收缩至0.59°,有效平衡了大通光量与高分辨力间的矛盾。仿真分析显示,系统在全焦段范围内像质稳定。该设计方案有效降低了系统包络尺寸,且公差分析表明其满足工程实现要求,可为航天器自主避障载荷设计提供参考。 展开更多
关键词 离轴三反 无焦系统 探测成像一体化 变焦系统 光学设计
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