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Effects of γ-ray and electron irradiation on microstructural evolution and mechanical properties of SnPb eutectic solder joints 认领 引用
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作者 Qi-long GUAN Chun-jin HANG +6 位作者 Wei ZHANG Sheng-li LI Xiao-jiu TANG Dan YU Ying DING Xiu-li WANG Yu-bao ZHANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2026年第3期902-916,共15页
The effects ofγ-ray and electron irradiation on the microstructural evolution and mechanical properties of SnPb eutectic solder joints were investigated.Following electron irradiation,the SnO2phase induced byγ-ra... The effects ofγ-ray and electron irradiation on the microstructural evolution and mechanical properties of SnPb eutectic solder joints were investigated.Following electron irradiation,the SnO2phase induced byγ-ray irradiation transformed intoβ-Sn,and the dislocation density in theβ-Sn crystal decreased.Moreover,numerous point defect clusters formed in theβ-Sn crystal,some of which transformed into an amorphous phase,increasing the amorphous layer thickness.Meanwhile,electron irradiation likewise resulted in rotation of the(220)plane ofβ-Sn nanograins and reduction of SnO2in theβ-Sn crystal.Additionally,upon exposure toγ-ray and electron irradiation,the average shear strength of the solder balls was initially increased by 10.10%,followed by a decrease of 3.53%and 4.77%,respectively.The plasticity and the dimple count on the fracture surfaces of the solder joint initially decreased but subsequently increased. 展开更多
关键词 combined irradiation SnPb eutectic solder joints SnO2reduction irradiation damage β-Sn nanograin rotation
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Epithelioid angiomyolipoma of the liver:Cross-sectional imaging findings of 10 immunohistochemically-verified cases 认领 引用 被引量:31
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作者 Peng-Ju Xu Yan Shan +3 位作者 Fu-Hua Yan Yuan Ji Ying Ding Mei-Lin Zhou 《World Journal of Gastroenterology》 SCIE CAS 2009年第36期4576-4581,共6页
AIM: To retrospectively evaluate the computed tomography (CT)/magnetic resonance imaging (MRI) imaging features of epithelioid angiomyolipoma of the liver (Epi-HAML), with pathology as a reference. METHODS: Th... AIM: To retrospectively evaluate the computed tomography (CT)/magnetic resonance imaging (MRI) imaging features of epithelioid angiomyolipoma of the liver (Epi-HAML), with pathology as a reference. METHODS: The CT/MRI findings (number, diameter, lobar location, and appearance of lesions) in a series of 10 patients with 12 pathologically proven epithelioid angiomyolipomas of the liver were retrospectively analyzed. The imaging features, including attenuation/ signal intensity characteristics, presence of fat, hypervascular, outer rim, and vessels within lesion, were evaluated and compared with that of non-Epi- HAML in 11 patients (13 lesions). The Fisher exact test was used to compare difference in probability of imaging features between the two types. RESULTS: For 21 patients, CT images of 15 patients and MR images of six patients were available. No patient underwent two examinations. For the 15 patients with a CT scan, all HAML lesions in the two groups (10 Epi-HAML and seven non-Epi-HAML) manifested as hypoattenuation. For the six patients with MRI, all lesions (two Epi-HAML and six non-Epi- HAML) were hypointense on TlWI (fat suppression) and hyperintense on T2WI. There were 10 non-Epi-HAML, but only two Epi-HAML lesions showed the presence of fat, which significantly different between the two types (P = 0.005). On the dynamic contrast enhancement (DCE) imaging, eight Epi-HAML, and 13 non-Epi lesions manifested as hypervascular. Punctate or curved vessels were displayed in 10 Epi-HAML as well as in nine non- Epi lesions and outer rim enhancement could be found with eight Epi-HAML as well as six non-Epi lesions. CONCLUSION: Little or no presence of adipose tissue was found to be an imaging feature of Epi- HAML, compared with the non-Epi type. In addition, hypervascularity with opacification of central punctiform or filiform vessels on DCE would be a characteristic enhancement pattern for Epi-HAML. 展开更多
关键词 Epithelioid angiomyolipoma Liver Immunohistochemical staining Magnetic resonance imaging Computed X-ray tomography
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Correlation between positive degree and psychological distress in patients with interstitial lung disease 认领 引用
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作者 Ying Ding Tian-Yu Chen +5 位作者 Su-Hong Wang Xi-Yao Chen Long Zhang Jun-Kang Huang-Fu Jun Zhou Shu-Hong Guan 《World Journal of Psychiatry》 SCIE 2026年第6期357-367,共11页
BACKGROUND Extant studies have explored the independent influencing factors of positivity or psychological distress in patients with interstitial lung disease(ILD);however,few studies have hitherto systematically anal... BACKGROUND Extant studies have explored the independent influencing factors of positivity or psychological distress in patients with interstitial lung disease(ILD);however,few studies have hitherto systematically analyzed the correlation between positivity or psychological distress in these patients.AIM To explore the correlation between disease management positivity and psychological distress in patients with ILD.METHODS Convenience sampling was used to select 370 patients with ILD treated in The First People’s Hospital of Changzhou(The Third Affiliated Hospital of Soochow University)from July 2023 to January 2025.We obtained data via a general information questionnaire,the Patient Activation Measure(PAM),and Kessler Psychological Distress Scale(K10).Pearson’s correlation analysis was conducted to assess the correlation between positivity and psychological distress.Multiple linear regression analyzed the factors that affected psychological distress.A restricted cubic spline model examined the dose-response relationship between the PAM and K10 scores.RESULTS The total PAM and K10 scores were 50.51±5.48 and 32.62±5.60,respectively.Significant differences were observed in the K10 scores among patients based on education level,dyspnea level,and the Perceived Social Support Scale score(P<0.05).Psychological distress was negatively correlated with cognition,action,belief,skill,and the PAM score(all P<0.05).Multiple linear regression analysis identified education level,dyspnea,Perceived Social Support Scale score,and PAM score as the main factors that influenced psychological distress(P<0.05).Restricted cubic spline curve fitting indicated a negative linear relationship between the PAM and K10 scores,adjusted for covariates(P for overall<0.001,P for non-linear=0.188).CONCLUSION Positivity is negatively correlated with psychological distress in patients with ILD.Clinically,attention should be paid to patients’psychological state to enhance their positivity. 展开更多
关键词 Interstitial lung disease Positiveness Psychological distress Correlation Restricted cubic spline Influencing factors
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Evidence for Multiple Underlying Fermi Surface and Isotropic Energy Gap in the Cuprate Parent Compound Ca2CuO2Cl2 认领 引用 被引量:1
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作者 Cheng Hu Jian-Fa Zhao +9 位作者 Ying Ding Jing Liu Qiang Gao Lin Zhao Guo-Oong Liu Li Yu Chang-Qing Jin Chuang-Tian Chen Zu-Yan Xu Xing-Jiang Zhou 《Chinese Physics Letters》 SCIE EI CAS CSCD 2018年第6期84-89,共6页
The parent compounds of the high-temperature cuprate superconductors are Mott insulators.It has been generally agreed that understanding the physics of the doped Mott insulators is essential to understanding the mecha... The parent compounds of the high-temperature cuprate superconductors are Mott insulators.It has been generally agreed that understanding the physics of the doped Mott insulators is essential to understanding the mechanism of high temperature superconductivity.A natural starting point is to elucidate the basic electronic structure of the parent compound.Here we report comprehensive high resolution angle-resolved photoemission measurements on Ca_2CuO_2Cl_2,a Mott insulator and a prototypical parent compound of the cuprates.Multiple underl.ying Fermi surface sheets are revealed for the first time.The high energy waterfall-like band dispersions exhibit different behaviors near the nodal and antinodal regions.Two distinct energy scales are identified:a d-wave-like low energy peak dispersion and a nearly isotropic lower Hubbard band gap.These observations provide new information of the electronic structure of the cuprate parent compound,which is important for understanding the anomalous physical properties and superconductivity mechanism of the high temperature cuprate superconductors. 展开更多
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Improvement in acupoint selection for acupuncture of nerves surrounding the injury site: electro-acupuncture with Governor vessel with local meridian acupoints 认领 引用 被引量:14
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作者 Guan-heng He Jing-wen Ruan +3 位作者 Yuan-shan Zeng Xin Zhou Ying Ding Guang-hui Zhou 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第1期128-135,共8页
Peripheral nerve injury not only affects the site of the injury, but can also induce neuronal apop- tosis at the spinal cord. However, many acupuncture clinicians still focus only on the injury site, selecting acupoin... Peripheral nerve injury not only affects the site of the injury, but can also induce neuronal apop- tosis at the spinal cord. However, many acupuncture clinicians still focus only on the injury site, selecting acupoints entirely along the injured nerve trunk and neglecting other regions; this may delay onset of treatment efficacy and rehabilitation. Therefore, in the present study, we compared the clinical efficacy of acupuncture at Governor vessel and local meridian acupoints combined (GV/LM group) with acupuncture at local meridian acupoints alone (LM group) in the treatment of patients with peripheral nerve injury. In the GV/LM group (n = 15), in addition to meridian acupoints at the injury site, the following acupoints on the Governor vessel were stimulated: Baihui (GV20), Fengfu (GV16), Dazhui (GV14), and Shenzhu (GV12), selected to treat nerve injury of the upper limb, and Jizhong (GV6), Mingmen (GV4), Yaoyangguan (GV3), and Yaoshu (GV2) to treat nerve injury of the lower limb. In the LM group (n = 15), only me- ridian acupoints along the injured nerve were selected. Both groups had electroacupuncture treatment for 30 minutes, once a day, 5 times per week, for 6 weeks. Two cases dropped out of the LM group. A good or excellent clinical response was obtained in 80% of the patients in the GV/ LM group and 38.5% of the LM group. In a second study, an additional 20 patients underwent acupuncture with the same prescription as the GV/LM group. Electomyographic nerve conduc- tion tests were performed before and after acupuncture to explore the mechanism of action of the treatment. An effective response was observed in 80.0% of the patients, with greater motor nerve conduction velocity and amplitude after treatment, indicating that electroacupuncture on specific Governor vessel acupoints promotes functional motor nerve repair after peripheral nerve injury. In addition, electromyography was performed before, during and after electroacu- puncture in one patient with radial nerve injury. After a single session, the patient's motor nerve conduction velocity increased by 23.2%, indicating that electroacupuncture at Governor vessel acupoints has an immediate therapeutic effect on peripheral nerve injury. Our results indicate that Governor vessel and local meridian acupoints used simultaneously promote functional repair after peripheral nerve injury. The mechanism of action may arise from an improvement of the local microenvironment in injured nervous tissue, as well as immediate effects of Governor vessel and local meridian acupoint stimulation to ensure the continuity between the peripheral and central nervous systems. 展开更多
关键词 nerve regeneration peripheral nerve injury acupuncture electroacupuncture Governorvessel acupoints local acupoints eleetrophysiology spinal cord motor nerve conduction functionalrepair neural regeneration
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Characterization and in-situ formation mechanism of tungsten carbide reinforced Fe-based alloy coating by plasma cladding 认领 引用 被引量:2
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作者 Mi-qi Wang Ze-hua Zhou +2 位作者 Lin-tao Wu Ying Ding Ze-hua Wang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2018年第4期439-443,共5页
The precursor carbonization method was first applied to prepare W–C compound powder to perform the in-situ synthesis of the WC phase in a Fe-based alloy coating. The in-situ formation mechanism during the cladding pr... The precursor carbonization method was first applied to prepare W–C compound powder to perform the in-situ synthesis of the WC phase in a Fe-based alloy coating. The in-situ formation mechanism during the cladding process is discussed in detail. The results reveal that fine and obtuse WC particles were successfully generated and distributed in Fe-based alloy coating via Fe/W–C compound powders. The WC particles were either surrounded by or were semi-enclosed in blocky M7C3 carbides. Moreover, net-like structures were confirmed as mixtures of M23C6 and α-Fe; these structures were transformed from M7C3. The coarse herringbone M6C carbides did not only derive from the decomposition of M7C3 but also partly originated from the chemical reaction at the α-Fe/M23C6 interface. During the cladding process, the phase evolution of the precipitated carbides was WC → M7C3 → M23C6 + M6C. 展开更多
关键词 precursor carbonization tungsten carbide (WC) microstructure in-situ formation mechanism phase evolution
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Understanding the Correlations between Social Attention and Topic Trends of Scientific Publications 认领 引用 被引量:2
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作者 Xianlei Dong Jian Xu +3 位作者 Ying Ding Chenwei Zhang Kunpeng Zhang Min Song 《Journal of Data and Information Science》 2016年第1期28-49,共22页
Purpose: We propose and apply a simplified nowcasting model to understand the correlations between social attention and topic trends of scientific publications. Design/methodology/approach: First, topics are generat... Purpose: We propose and apply a simplified nowcasting model to understand the correlations between social attention and topic trends of scientific publications. Design/methodology/approach: First, topics are generated from the obesity corpus by using the latent Dirichlet allocation (LDA) algorithm and time series of keyword search trends in Google Trends are obtained. We then establish the structural time series model using data from January 2004 to December 2012, and evaluate the model using data from January 2013. We employ a state-space model to separate different non-regression components in an observational time series (i.e. the tendency and the seasonality) and apply the "spike and slab prior" and stepwise regression to analyze the correlations between the regression component and the social media attention. The two parts are combined using Markov-chain Monte Carlo sampling techniques to obtain our results. Findings: The results of our study show that (1) the number of publications on child obesity increases at a lower rate than that of diabetes publications; (2) the number of publication on a given topic may exhibit a relationship with the season or time of year; and (3) there exists a correlation between the number of publications on a given topic and its social media attention, i.e. the search frequency related to that topic as identified by Google Trends. We found that our model is also able to predict the number of publications related to a given topic. 展开更多
关键词 First we study a correlation rather than causality between topics'trends and social media. As a result the relationships might not be robust so we cannot
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Using Machine Reading to Understand Alzheimer's and Related Diseases from the Literature 认领 引用
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作者 Satoshi Tsutsui Yi Bu Ying Ding 《Journal of Data and Information Science》 CSCD 2017年第4期81-94,共14页
Purpose: This paper aims to better understand a large number of papers in the medical domain of Alzheimer's disease (AD) and related diseases using the machine reading approach. Design/methodology/approach: The s... Purpose: This paper aims to better understand a large number of papers in the medical domain of Alzheimer's disease (AD) and related diseases using the machine reading approach. Design/methodology/approach: The study uses the topic modeling method to obtain an overview of the field, and employs open information extraction to further comprehend the field at a specific fact level. Findings: Several topics within the AD research field are identified, such as the Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS), which can help answer the question of how A1DS/HIV and AD are very different yet related diseases. Research limitations: Some manual data cleaning could improve the study, such as removing incorrect facts found by open information extraction. Practical implications: This study uses the literature to answer specific questions on a scientific domain, which can help domain experts find interesting and meaningful relations among entities in a similar manner, such as to discover relations between AD and AIDS/HIV. Origlnality/value: Both the overview and specific information from the literature are obtained using two distinct methods in a complementary manner. This combination is novel because previous work has only focused on one of them, and thus provides a better way to understand an important scientific field using data-driven methods. 展开更多
关键词 Machine reading Alzheimer's disease Knowledge discovery Data mining
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Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury 认领 引用 被引量:4
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作者 Wenrui Qu Xiangbing Wu +13 位作者 Wei Wu Ying Wang Yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi Xia George Smith Rui Li Nai-Kui Liu Xiao-Ming Xu 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第5期1467-1482,共16页
Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration... Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal cord.Here we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord injury.We report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal directions.Such Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder functions.Importantly,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord injury.These findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury. 展开更多
关键词 axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation
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Mechanisms of ductile-to-brittle transition in Sn−3.0Ag−0.5Cu solder alloy at cryogenic temperature 认领 引用
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作者 Sheng-li LI Chun-jin HANG +7 位作者 Qi-long GUAN Xiao-jiu TANG Ning ZHOU Yan-hong TIAN Wei ZHANG Dan YU Ying DING Xiu-li WANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2025年第4期1281-1291,共11页
The inherent brittle behavior and ductile-to-brittle transition(DBT)mechanism of Sn−3.0Ag−0.5Cu(SAC305)solder alloy at the liquid nitrogen temperature(LNT,77 K)were investigated through uniaxial tensile experiments co... The inherent brittle behavior and ductile-to-brittle transition(DBT)mechanism of Sn−3.0Ag−0.5Cu(SAC305)solder alloy at the liquid nitrogen temperature(LNT,77 K)were investigated through uniaxial tensile experiments conducted at different temperatures.Dynamic recovery and recrystallization of SAC305 solder alloy at room temperature(RT,293 K)activate a softening process.Conversely,intersecting and none-intersecting deformation twins,embedded in body-centered tetragonal Sn,enhance tensile strength and stabilize strain hardening rate,while suppressing the elongation of the alloy at LNT.The irreconcilable velocity difference between twin thickening(~8μm/s)and dislocation slip(4μm/s)results in premature brittle fracture,during the linear hardening and DBT.Moreover,the secondary phases degrade the mechanical property of SAC305 solder alloy,and micro-cracks appear between Cu6Sn5and Ag3Sn in the eutectic matrix. 展开更多
关键词 SAC305 deformation twinning secondary phases tensile property cryogenic temperature
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Quantum well engineering in quasi-2D perovskites unlocks efficiency-stability synergy for photovoltaics 认领 引用
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作者 Jingwei Mao Yi Wei +7 位作者 Ying Ding Yufeng Liu Junhui Wang Kaifeng Wu Zijian Deng Ze Yu Yefu Liu Huolin Huang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2025年第12期1042-1051,I0022,共10页
Quasi-2D perovskites offer enhanced stability for photovoltaic applications but suffer from compromised charge transport due to uncontrolled phase separation and nonideal quantum well(QW)distribution.Contrary to the p... Quasi-2D perovskites offer enhanced stability for photovoltaic applications but suffer from compromised charge transport due to uncontrolled phase separation and nonideal quantum well(QW)distribution.Contrary to the prevailing belief that maximizing 3D-like phases optimizes performance,we demonstrate that strategic narrowing QW distribution into high-n phases while avoiding undesirable graded configurations(common in quasi-2D systems)unlocks unprecedented efficiency-stability synergy.Using 1,4-cyclohexanedimethanamine(CDMA)as a crystallization-directing spacer,we realize three advances.(a)High-n phases with minimized n-value dispersion establish a uniform energy landscape,significantly reducing interphase charge transfer barriers and suppressing voltage losses.(b)Lattice matching between adjacent high-n phases substantially alleviates microstrain accumulation,thereby mitigating defect generation and non-radiative recombination.(c)Strategic predominance of robust high-n phases achieves dual optimization:it excludes hygroscopic 3D-like phases and eliminates mobility-limiting lown phases,thereby ensuring efficient charge dynamics while fortifying the perovskite's intrinsic phase stability.The synergy of these advances enables the CDMA PSCs to achieve a champion efficiency of 19.02%,making them among the highest-efficiency quasi-2D DJ PSCs.The unencapsulated device demonstrated remarkable stability,maintaining 92%of its initial PCE after 5000 h in air.This work redefines phase engineering priorities,demonstrating that manipulating QW distribution in quasi-2D perovskites has the potential to address the efficiency-stability trade-off. 展开更多
关键词 Quasi-2D perovskites Distribution of quantum wells Carrier transport Strain Stability
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Radiofrequency ablation or microwave ablation combined with transcatheter arterial chemoembolization in treatment of hepatocellular carcinoma by comparing with radiofrequency ablation alone 认领 引用 被引量:32
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作者 Yongxiang Yi Yufeng Zhang +9 位作者 Qiang Wei Liang Zhao Jianbo Han Yan Song Ying Ding Guilan Lu Junmao Liu Huaiying Ding Feng Dai Xiaojun Tang 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2014年第1期112-118,共7页
Objective:To compare radiofrequency ablation (RFA) or microwave ablation (MWA) and transcatheter arterial chemoembolization (TACE) with RFA or MWA monotherapy in hepatocellular carcinoma (HCC).Methods:A pros... Objective:To compare radiofrequency ablation (RFA) or microwave ablation (MWA) and transcatheter arterial chemoembolization (TACE) with RFA or MWA monotherapy in hepatocellular carcinoma (HCC).Methods:A prospective,randomized,controlled trial was conducted on 94 patients with HCC ≤7 cm at a single tertiary referral center from June 2008 to June 2010 at the Department of Hepatobiliary Surgery,the Second Affiliated Hospital of Southeast University.The patients were randomly assigned into the TACERFA or TACE-MWA (combined treatment group) and the RFA-alone or MWA-alone groups (control group).The primary end point was overall survival.The secondary end point was recurrence-free survival,and the tertiary end point was adverse effects.Results:Until the time of censor,17 patients in the TACE-RFA or TACE-MWA group had died.The median follow-up time of the patients who were still alive for the TACE-RFA or TACE-MWA group was 47.5±11.3 months (range,29 to 62 months).The 1-,3-and 5-year overall survival for the TACE-RFA or TACE-MWA group was 93.6%,68.1% and 61.7%,respectively.Twenty-five patients in the RFA or MWA group had died.The median follow-up time of the patients who were still alive for the RFA or MWA group was 47.0±12.9 months (range,28 to 62 months).The 1-,3-and 5-year overall survival for the RFA or MWA group was 85.1%,59.6% and 44.7%,respectively.The patients in the TACE-RFA or TACE-MWA group had better overall survival than the RFA or MWA group [hazard ratio (HR),0.526; 95% confidence interval (95% CO,0.334-0.823; P=0.002],and showed better recurrence-free survival than the RFA or MWA group (HR,0.582; 95% CI,0.368-0.895; P=0.008).Conclusions:RFA or MWA combined with TACE in the treatment of HCC ≤7 cm was superior to RFA or MWA alone in improving survival by reducing arterial and portal blood flow due to TACE with iodized oil before RFA. 展开更多
关键词 Radiofrequency ablation (RFA) transcatheter arterial chemoembolization (TACE) hepatocellular carcinoma (HCC)
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单篇论著的引文扩散 认领 引用 被引量:26
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作者 闵超 Ying Ding +1 位作者 李江 孙建军 《情报学报》 CSSCI CSCD 北大核心 2018年第4期341-350,共10页
引文是连接科学知识的重要线索,为我们提供了理解知识产生、交流、转化乃至创新规律的金钥匙。引文不只是静态的统计分布,同时也是处于复杂科学系统中的动态增长过程。本文将引文理解为一种扩散过程,从多个维度重新审视引文扩散过程及... 引文是连接科学知识的重要线索,为我们提供了理解知识产生、交流、转化乃至创新规律的金钥匙。引文不只是静态的统计分布,同时也是处于复杂科学系统中的动态增长过程。本文将引文理解为一种扩散过程,从多个维度重新审视引文扩散过程及其基本要素、量化方式与增长机理。引文扩散体系中至少包含以下要素:时间环境、首次被引、引文高峰、最终引文数量、引文累积速度、引文生命周期、文献网络/生态系统,以及引文起飞。引文在微观结构上以引文级联为基本单元,从引文感染性与引文流行性两个维度进行扩散,有广播型与感染型两种典型扩散方式。引文扩散模式的巨大差异性源于其内在机理的作用,对于优先连接机制、老化机制与适应性机制以及创新机制与模仿机制的认识与进一步探索,将有助于对引文扩散进程的理解。对引文扩散的探讨对于科研评估、科学预测、科技政策制定等科技活动具有潜在价值。 展开更多
关键词 引文的扩散 扩散要素 扩散结构 扩散机理
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Decellularized optic nerve functional scaffold transplant facilitates directional axon regeneration and remyelination in the injured white matter of the rat spinal cord 认领 引用 被引量:9
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作者 Yu-Rong Bai Bi-Qin Lai +6 位作者 Wei-Tao Han Jia-Hui Sun Ge Li Ying Ding Xiang Zeng Yuan-Huan Ma Yuan-Shan Zeng 《Neural Regeneration Research》 SCIE CAS CSCD 2021年第11期2276-2283,共8页
Axon regeneration and remyelination of the damaged region is the most common repair strategy for spinal cord injury.However,achieving good outcome remains difficult.Our previous study showed that porcine decellularize... Axon regeneration and remyelination of the damaged region is the most common repair strategy for spinal cord injury.However,achieving good outcome remains difficult.Our previous study showed that porcine decellularized optic nerve better mimics the extracellular matrix of the embryonic porcine optic nerve and promotes the directional growth of dorsal root ganglion neurites.However,it has not been reported whether this material promotes axonal regeneration in vivo.In the present study,a porcine decellularized optic nerve was seeded with neurotrophin-3-overexpressing Schwann cells.This functional scaffold promoted the directional growth and remyelination of regenerating axons.In vitro,the porcine decellularized optic nerve contained many straight,longitudinal channels with a uniform distribution,and microscopic pores were present in the channel wall.The spatial micro topological structure and extracellular matrix were conducive to the adhesion,survival and migration of neural stem cells.The scaffold promoted the directional growth of dorsal root ganglion neurites,and showed strong potential for myelin regeneration.Furthermore,we transplanted the porcine decellularized optic nerve containing neurotrophin-3-overexpressing Schwann cells in a rat model of T10 spinal cord defect in vivo.Four weeks later,the regenerating axons grew straight,the myelin sheath in the injuredransplanted area recovered its structure,and simultaneously,the number of inflammatory cells and the expression of chondroitin sulfate proteoglycans were reduced.Together,these findings suggest that porcine decellularized optic nerve loaded with Schwann cells overexpressing neurotrophin-3 promotes the directional growth of regenerating spinal cord axons as well as myelin regeneration.All procedures involving animals were conducted in accordance with the ethical standards of the Institutional Animal Care and Use Committee of Sun Yat-sen University(approval No.SYSU-IACUC-2019-B034)on February 28,2019. 展开更多
关键词 axonal regeneration decellularized optic nerve directional regeneration functional scaffold microenvironment neurotrophin-3 optic nerve remyelination Schwann cells tissue engineering white matter injury
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Research Progress on the Solder Joint Reliability of Electronics Using in Deep Space Exploration 认领 引用 被引量:8
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作者 Qilong Guan Chunjin Hang +4 位作者 Shengli Li Dan Yu Ying Ding Xiuli Wang Yanhong Tian 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2023年第2期16-28,共13页
The spacecraft for deep space exploration missions will face extreme environments,including cryogenic temperature,intense radiation,wide-range temperature variations and even the combination of conditions mentioned ab... The spacecraft for deep space exploration missions will face extreme environments,including cryogenic temperature,intense radiation,wide-range temperature variations and even the combination of conditions mentioned above.Harsh environments will lead to solder joints degradation or even failure,resulting in damage to onboard electronics.The research activities on high reliability solder joints using in extreme environments can not only reduce the use of onboard protection devices,but effectively improve the overall reliability of spacecraft,which is of great significance to the aviation industry.In this paper,we review the reliability research on SnPb solder alloys,Sn-based lead-free solder alloys and In-based solder alloys in extreme environments,and try to provide some suggestions for the follow-up studies,which focus on solder joint reliability under extreme environments. 展开更多
关键词 Deep space exploration Extreme environments Solder joints Microstructure Electronics Reliability
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Streptozotocin-induced expression of Ngn3 and Pax4 in neonatal rat pancreaticα-cells 认领 引用 被引量:5
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作者 Xiao-Di Liang Yuan-Yuan Guo +4 位作者 Ming Sun Ying Ding Ning Wang Li Yuan Wei De 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第23期2812-2820,共9页
AIM:To investigate the mechanism behindβ-cell regeneration in neonatal rat pancreas treated with strep-tozotocin(STZ).METHODS:Neonatal Sprague Dawley rats were intra-peritoneally injected with 70 mg/kg STZ.Body weigh... AIM:To investigate the mechanism behindβ-cell regeneration in neonatal rat pancreas treated with strep-tozotocin(STZ).METHODS:Neonatal Sprague Dawley rats were intra-peritoneally injected with 70 mg/kg STZ.Body weight,pancreas weight and blood glucose were recorded every two days after the treatment.To identify the expression and location of transcription factors in the rat pancreas,double immunofluorescent staining was performed using antibodies to specific cell markers and transcription factors.RESULTS:Expression of Neurogenin 3(Ngn3),a marker for endocrine precursor cells,was observed by immunofluorescence in a fewβ-cells and many a-cells.The expression reached a peak 12 d after treatment.Pax4,a transcription factor that lies downstream of Ngn3 and plays an important role inβ-cell differentiation,was also expressed in theα-cells of STZ-treated rats.We did not observe significant changes in Nkx6.1,which is essential forβ-cell maturation in the treated rats.CONCLUSION:α-cells dedifferentiated into endocrine precursor cells and acquired the ability to dedifferentiate in the neonatal rat pancreas after STZ treatment. 展开更多
关键词 Pancreatic remodeling Dedifferentiation Endocrine precursor cells Streptozotocin Transcriptionfactors
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Removal of microcystin-LR from drinking water using a bamboo-based charcoal adsorbent modified with chitosan 认领 引用 被引量:5
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作者 Hangjun Zhang Guoying Zhu +5 位作者 Xiuying Jia Ying Ding Mi Zhang Qing Gao Ciming Hu Shuying Xu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2011年第12期1983-1988,共6页
A new kind of low-cost syntactic adsorbent from bamboo charcoal and chitosan was developed for the removal of microcystin-LR from drinking water. Removal effciency was higher for the syntactic adsorbent when the amoun... A new kind of low-cost syntactic adsorbent from bamboo charcoal and chitosan was developed for the removal of microcystin-LR from drinking water. Removal effciency was higher for the syntactic adsorbent when the amount of bamboo charcoal was increased. The optimum dose ratio of bamboo charcoal to chitosan was 6:4, and the optimum amount was 15 mg/L; equilibrium time was 6 hr. The adsorption isotherm was non-linear and could be simulated by the Freundlich model (R2 = 0.9337). Adsorption efficiency was strongly afflected by pH and natural organic matter (NOM). Removal efficiency was 16% higher at pH 3 than at pH 9. Efficiency rate was reduced by 15% with 25 mg/L NOM (UV254 = 0.089 cm-1) in drinking water. This study demonstrated that the bamboo charcoal modified with chitosan can effectively remove microcystin-LR from drinking water. 展开更多
关键词 adsorption bamboo charcoal chitosan microcystin-LR
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Usefulness of two-point Dixon fat-water separation technique in gadoxetic acid-enhanced liver magnetic resonance imaging 认领 引用 被引量:2
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作者 Ying Ding Sheng-Xiang Rao +2 位作者 Cai-Zhong Chen Ren-Chen Li Meng-Su Zeng 《World Journal of Gastroenterology》 SCIE CAS 2015年第16期5017-5022,共6页
AIM:To compare differences between volumetric interpolated breath-hold examination(VIBE) using two-point Dixon fat-water separation(Dixon-VIBE) and chemically selective fat saturation(FS-VIBE) with magnetic resonance ... AIM:To compare differences between volumetric interpolated breath-hold examination(VIBE) using two-point Dixon fat-water separation(Dixon-VIBE) and chemically selective fat saturation(FS-VIBE) with magnetic resonance imaging examination.METHODS:Forty-nine patients were included, who were scanned with two VIBE sequences(Dixon-VIBE and FS-VIBE) in hepatobiliary phase after gadoxetic acid administration.Subjective evaluations including sharpness of tumor, sharpness of vessels, strength and homogeneity of fat suppression, and artifacts that were scored using a 4-point scale.The liver-to-lesion contrast was also calculated and compared.RESULTS:Dixon-VIBE with water reconstruction had significantly higher subjective scores than FS-VIBE in strength and homogeneity of fat suppression(< 0.0001) but lower scores in sharpness of tumor(P < 0.0001), sharpness of vessels(P = 0.0001), and artifacts(P = 0.034).The liver-to-lesion contrast on Dixon-VIBE images was significantly lower than that on FS-VIBE(16.6% ± 9.4% vs 23.9% ± 12.1%, P = 0.0001).CONCLUSION:Dixon-VIBE provides stronger and more homogenous fat suppression than FS-VIBE, while has lower clarity of focal liver lesions in hepatobiliary phase after gadoxetic acid administration. 展开更多
关键词 Dixon-volumetric interpolated breath-holdexamination Fat saturation-volumetric interpolatedbreath-hold examination Gadoxetic acid Volumetricinterpolated breath-hold examination Magnetic resonance imaging
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Disappearance of Superconductivity and a Concomitant Lifshitz Transition in Heavily Overdoped Bi_2Sr_2CuO_6 Superconductor Revealed by Angle-Resolved Photoemission Spectroscopy 认领 引用 被引量:2
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作者 Ying Ding Lin Zhao +22 位作者 Hong-Tao Yan Qiang Gao Jing Liu Cheng Hu Jian-Wei Huang Cong Li Yu Xu Yong-Qing Cai Hong-Wao Rong Ding-Song Wu Chun-Yao Song Hua-Xue Zhou Xiao-Li Dong Guo-Dong Liu Qing-Yan Wang Shen-Jin Zhang Zhi-Min Wang Feng-Feng Zhang Feng Yang Qin-JunPeng Zu-Yan Xu Chuang-Tian Chen X.J.Zhou 《Chinese Physics Letters》 SCIE EI CAS CSCD 2019年第1期60-64,共5页
By partially doping Pb to effectively suppress the superstructure in single-layered cuprate Bi_2Sr_2CuO6+δ(Pb-Bi2201) and annealing them in vacuum or in high pressure oxygen atmosphere, a series of high quality Pb... By partially doping Pb to effectively suppress the superstructure in single-layered cuprate Bi_2Sr_2CuO6+δ(Pb-Bi2201) and annealing them in vacuum or in high pressure oxygen atmosphere, a series of high quality Pb-Bi2201 single crystals are obtained with T_c covering from 17 K to non-superconducting in the overdoped region. High resolution angle resolved photoemission spectroscopy measurements are carried out on these samples to investigate the evolution of the Fermi surface topology with doping in the normal state. Clear and complete Fermi surfaces are observed and quantitatively analyzed in all of these overdoped Pb-Bi2201 samples. A Lifshitz transition from holelike Fermi surface to electron-like Fermi surface with increasing doping is observed at a doping level of ~0.35. This transition coincides with the change that the sample undergoes superconducting-to-non-superconducting states.Our results reveal the emergence of an electron-like Fermi surface and the existence of a Lifshitz transition in heavily overdoped Bi2201 samples. This provides important information in understanding the connection between the disappearance of superconductivity and the Lifshitz transition in the overdoped region. 展开更多
关键词 Angular resolved light emission spectrometry Concomitant Lifshitz Transition Bi2Sr2CuO6
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Evolution of incommensurate superstructure and electronic structure with Pb substitution in(Bi2-xPbx)Sr2CaCu2O8+δ superconductors 认领 引用 被引量:1
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作者 Jing Liu Lin Zhao +24 位作者 Qiang Gao Ping Ai Lu Zhang Tao Xie( Jian-Wei Huang Ying Ding Cheng Hu Hong-Tao Yan Chun-Yao Song Yu Xu Cong Li Yong-Qing Cai Hong-Tao Rong Ding-Song Wu Guo-Dong Liu Qing-Yan Wang Yuan Huang Feng-Feng Zhang Feng Yang Qin-Jun Peng Shi-Liang Li Huai-Xin Yang Jian-Qi Li Zu-Yan Xu Xing-Jiang Zhou 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第7期102-110,共9页
High-quality Bi2-xPbxSr2 CaCu2O8+δ(Bi2212) single crystals have been successfully grown by the traveling solvent floating zone technique with a wide range of Pb substitution(x = 0–0.8).The samples are characterized ... High-quality Bi2-xPbxSr2 CaCu2O8+δ(Bi2212) single crystals have been successfully grown by the traveling solvent floating zone technique with a wide range of Pb substitution(x = 0–0.8).The samples are characterized by transmission electron microscope(TEM) and measured by high resolution laser-based angle-resolved photoemission spectroscopy(ARPES) with different photon energies.A systematic evolution of the electronic structure and superstructure with Pb substitution has been revealed for the first time.The superstructure shows a significant change with Pb substitution and the incommensurate modulation vector(Q) decreases with increasing Pb substitution.In the meantime, the superstructure intensity from ARPES measurements also decreases dramatically with increasing Pb concentration.The superstructure in Bi2212 can be effectively suppressed by Pb substitution and it nearly disappears with a Pb substitution of x = 0.8.We also find that the superstructure bands in ARPES measurements depend sensitively on the photon energy of lasers used;they can become even stronger than the main band when using a laser photon energy of 10.897 eV.These results provide important information on the origin of the incommensurate superstructure and its control and suppression in bismuth-based high temperature superconductors. 展开更多
关键词 Bi2-xPbxSr2CaCu2O8+δ superstructure electronic structure angle-resolved photoemission spectroscopy(ARPES) modulation
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