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Artificial humic acid promotes carbon sequestration in the rice-soil system 认领 引用 被引量:1
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作者 Zeyu ZHANG Yu QIAO +4 位作者 Dongxing XIE Jicheng HAN Zhuqing LIU Ying ZHAO Fan YANG 《Pedosphere》 SCIE CAS CSCD 2026年第2期497-510,共14页
Artificial humic acid(AHA)is a new exogenous organic material with enormous carbon(C)sequestration potential.However,the effects of applying AHA under different irrigation regimes on C sequestration in the rice-soil s... Artificial humic acid(AHA)is a new exogenous organic material with enormous carbon(C)sequestration potential.However,the effects of applying AHA under different irrigation regimes on C sequestration in the rice-soil system and the underlying mechanisms still need to be clarified.This study employed C isotope labeling technology to analyze the photosynthetic C sequestration capacity,C transport capacity of rice roots,and greenhouse gas emission flux in the rice-soil system under different irrigation regimes and AHA application conditions.The results showed that as the amount of AHA application increased,the leaf area and chlorophyll concentration gradually increased,and the ribulose-1,5-bisphosphate carboxylase/oxygenase(Rubisco)activity first increased and then decreased under two irrigation regimes(conventional flooding and alternate wetting and drying irrigation).In the alternate wetting and drying irrigation with 300 mg kg-1AHA application treatment(DWI3),the photosynthetic C fixation was the highest,with the net photosynthetic rate increasing by 65.35% compared to the alternate wetting and drying irrigation without applying AHA treatment(DWI0).Meanwhile,the organic acid concentration in root exudates,biomass,length,surface area,and length density were also the highest in the DWI3 treatment.Besides,the content of~(13)C in soil was the highest in the DWI3 treatment,closely related to the strongest photosynthetic C fixation and root transport capacity,as well as the lowest greenhouse gas emission flux.Therefore,it is recommended to apply 300 mg kg-1AHA with alternate wetting and drying irrigation for C sequestration,water conservation,and sustainable agricultural development. 展开更多
关键词 alternate wetting and drying irrigation C isotope labeling chlorophyll fluorescence conventional flooding irrigation isotope tracing technology photosynthesis root exudates
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New functional metal-organic framework(MOF) based optical thermometer by the post-synthesis doping rare earth ions into MOF 认领 引用 被引量:1
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作者 Ying Zhao Yin-Hang Chai +4 位作者 Meng-Meng Zhai Qin-Ying Jin Xiaoyan Lu Yi-Dan Qiao Lu-Fang Ma 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第1期644-649,共6页
Ln@MOFs by anchoring rare metal ions(Ln) into metal-organic frameworks(MOFs) are proved to have great potential in the field of luminescent molecular thermometer.Nevertheless,the current research indicated that the po... Ln@MOFs by anchoring rare metal ions(Ln) into metal-organic frameworks(MOFs) are proved to have great potential in the field of luminescent molecular thermometer.Nevertheless,the current research indicated that the poor structural stability and low sensitivity hindered their application scope.In this work,a new MOF Zn-450 luminescent thermometer with multiple emission fluorescence characteristics was synthesized by the combination of 3,3,5,5-biphenyl tetracarboxylic acid(H4L) and Zn2+ ion under solvothermal conditions.Interestingly,a high relative sensitivity of 1.43 % K-1 was found within 80-300 K based on Zn-450.Subsequently,two high-sensitivity luminescent Ln@MOFs(Ln = Eu and Tb) were further fabricated by doping rare earth ions into Zn-450 based on the post-synthesis strategy.Among them,the Eu@Zn-450 demonstrates various luminous behaviors while achieving an increased relative sensitivity of 1.63 % K-1.In addition,the continuously visible red,pink,and purple luminescent emissions at the same temperature range were observed,suggesting that the Eu@Zn-450 could be utilized as a luminescent colorimetric molecular thermometer.Importantly,this work can present new possibilities for the development of rare earth-doped luminescence and its temperature sensing properties. 展开更多
关键词 MOFs Optical thermometer Post-synthesis functionalization Rare metal ions LED
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Synergistic machine learning and DFT screening strategy:Accelerating discovery of efficient perovskite passivators 认领 引用
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作者 Jianghao Liu Hongyan Lv +4 位作者 Pengyang Wang Guofu Hou Ying Zhao Xiaodan Zhang Qian Huang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第1期56-63,I0003,共8页
Efficient surface passivation is critical for achieving high-performance perovskite solar cells(PSCs),yet the discovery of optimal passivators remains a time-consuming,trial-and-error process.Here,we report a synergis... Efficient surface passivation is critical for achieving high-performance perovskite solar cells(PSCs),yet the discovery of optimal passivators remains a time-consuming,trial-and-error process.Here,we report a synergistic machine learning(ML)and density functional theory(DFT)approach that enables predictive and rapid identification of effective passivation materials.By training an XGBoost model(91.3%accuracy)with DFT-derived molecular descriptors and activity calculations,we identify 2-(4-aminophenyl)-3H-benzimidazol-5-amine(APBIA)as a promising passivator.Experimental validation demonstrates that APBIA effectively removes surface impurities and passivates defects within perovskite films,leading to a significant increase in power conversion efficiency(PCE)from 22.48%to 25.55%(certified as 25.02%).This ML-DFT framework provides a generalizable pathway for accelerating the development of advanced functional materials for photovoltaic applications. 展开更多
关键词 Perovskite solar cells Machine learning(ML) Density functional theory(DFT) Passivators Organic molecule
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2D/3D switchable display based on a polarization-multiplexed metasurface 认领 引用
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作者 JINGNAN LI HUAN ZHAO +6 位作者 BAOGANG QUAN SHUANGLIN YUE HAOWEN MA JUNHUI YAO YING ZHAO BIN HU JUAN LIU 《Photonics Research》 SCIE EI CAS CSCD 2026年第6期2635-2645,共11页
A 2D/3D switchable display based on the polarization-multiplexed metasurface is proposed.The designed metasurface is governed by the Pancharatnam-Berry(PB)phase,which performs the functionality of either a lens for 2D... A 2D/3D switchable display based on the polarization-multiplexed metasurface is proposed.The designed metasurface is governed by the Pancharatnam-Berry(PB)phase,which performs the functionality of either a lens for 2D display or a 4×4 lens array for 3D integral imaging(3D-II)display under different circularly polarized light illumination.As a proof of concept,a metallic metasurface on a SiO2 substrate is fabricated,and its lens and lens array operations are experimentally validated by focusing characterization.Using a commercial OLED panel as the light source in the experimental setup,we demonstrate a polarization-controlled display prototype capable of switching between high-resolution 2D images and full-parallax 3D scenes.The simulated and experimental results confirm the 2D/3D switching functionality of the proposed approach,offering promising potential for applications in floating,virtual reality/augmented reality,portable,and wearable display devices. 展开更多
关键词 D integral imaging focusing characteriza polarization multiplexed metasurface d display circularly polarized light lens Pancharatnam Berry phase OLED panel
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Tender energy spectroscopy beamline at the Shanghai Synchrotron Radiation Facility 认领 引用
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作者 Shu‑Min Yang Ling‑Ling Guo +12 位作者 Bing Nan Ying Zhao Yan‑Qing Wu Zhi Guo Chen Tian Bo Zhao Chao‑Fan Xue Jun Zhao Shuang Song Zhen‑Ye Liang Li‑Na Li Yong Wang Ren‑Zhong Tai 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2026年第1期94-106,共13页
This paper describes the design and performance of the tender energy spectroscopy beamline(BL16U1),a phase Ⅱ beamline,at the Shanghai Synchrotron Radiation Facility.The beamline,based on an in-vacuum undulator source... This paper describes the design and performance of the tender energy spectroscopy beamline(BL16U1),a phase Ⅱ beamline,at the Shanghai Synchrotron Radiation Facility.The beamline,based on an in-vacuum undulator source with 26 mm period,provides an operable energy range between 2.1 keV and 16 keV,covering the K-edges of P to Rb and L3-edges of Zr to Bi.The principal optical elements of the beamline are a toroidal mirror,a liquid nitrogen-cooled double-crystal monochromator,a high-harmonic-rejection mirror,and two pairs of Kirkpatrick–Baez(KB)mirrors.Three end-stations,including non-focusing,microprobe,and sub-microprobe types,are installed on the beamline.X-ray fluorescence(XRF)and X-ray absorption spectroscopy(XAS),including X-ray absorption near-edge structure(XANES)and extended X-ray absorption fine structure(EXAFS),are performed under vacuum or He atmosphere at the non-focusing end-station(with a beam spot size of∼670μm×710μm).Using two KB mirrors systems,micro-XRF(μXRF)mapping and micro-XANES(μXANES)studies can be performed with a spot size of approximately∼3.3μm×1.3μm at the microprobe end-station and with a smaller spot size of∼0.5μm×0.25μm at the sub-microprobe end-station.The non-focusing end-station was officially opened to users in January 2024.The microprobe and sub-microprobe end-stations will be opened to users in the near future.This paper presents the characteristics,short-term technical developments,and early experimental results of this new beamline. 展开更多
关键词 Tender energy X-ray spectroscopy X-ray fluorescence SSRF X-ray absorption spectroscopy(XAS) Microprobe
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Root structural remodeling under soil compaction for herbaceous plants 认领 引用
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作者 Qinwen Han Qingpei Yang +14 位作者 Binglin Guo Tino Colombi Junjian Wang Huifang Wu Zhipei Feng Zhi Zheng Zhenjiang Li Yue Zhang Meixu Han Qiang Li Junxiang Ding Xitian Yang Hannah M.Schneider Ying Zhao Deliang Kong 《Plant Diversity》 SCIE CAS CSCD 2026年第1期128-139,共12页
Soil compaction often imposes stress on root development and plant survival.However,root anatomical responses that enable persistent root growth and functioning under soil compaction remain unclear.We grew 10 herbaceo... Soil compaction often imposes stress on root development and plant survival.However,root anatomical responses that enable persistent root growth and functioning under soil compaction remain unclear.We grew 10 herbaceous species differing substantially in lateral root diameter,in soils with low(1.0 g cm-3)and high(1.4 g cm-3)bulk density,and assessed root traits including root biomass,anatomical structures,and respiration rates.Greater root thickening upon soil compaction was found in species with thicker first-order lateral roots,mainly due to larger cortical cell size.Both xylem vessel diameter and wall thickness increased more in compacted soils in these species.Despite these anatomical shifts,root respiration rate responded little to soil compaction across most species,likely due to the opposite investment in cortical cells and xylem vessels.Notably,root biomass,independent of root respiration rate and anatomical structures,determined whole-plant growth under soil compaction.Our study reveals two independent strategies of root response to soil compaction:anatomical remodeling for mechanical and metabolic maintenance,and root biomass investment for resource acquisition.These findings offer new insights for breeding and selecting species tolerant to soil compaction and highlight multidimensional strategies of plant adaptation to physical stress. 展开更多
关键词 Root anatomy Root respiration rate Soil compaction Cortex Xylem vessel Root biomass
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Fine mapping of the stripe rust resistance gene Yr85 in wheat 认领 引用
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作者 Xiangrui Cheng Huaizhou Li +12 位作者 Jiangna Han Ying Zhao Shuqing Yang Mingjie Xiang Yibo Zhang Xiaoting Wang Haohao Yan Shuaiwei Cao Dejun Han Jianhui Wu Zhensheng Kang Qingdong Zeng Shengjie Liu 《The Crop Journal》 SCIE CSCD 2026年第4期1267-1276,共10页
Breeding resistant wheat(Triticum aestivum)cultivars is the most efficient way to manage wheat stripe rust,a highly destructive disease caused by the fungal pathogen Puccinia striiformis f.sp.tritici(Pst).Therefore,th... Breeding resistant wheat(Triticum aestivum)cultivars is the most efficient way to manage wheat stripe rust,a highly destructive disease caused by the fungal pathogen Puccinia striiformis f.sp.tritici(Pst).Therefore,the exploration of new resistance genes is ongoing.The resistance gene Yr85 confers protection against predominant Pst races in China at all stages of plant development.Here,we fine-mapped Yr85 to a 0.12 cM interval between allele-specific quantitative PCR markers XK1B-61 and XK1B-65,corresponding to a 1.76 Mb region on chromosome 1BS in the IWGSC RefSeq v2.1 reference genome(wheat cultivar Chinese Spring),using 5507 F5 plants derived from heterozygous F4 plants,themselves descendants of an AvS×AvSYr85NIL cross.Haplotype analysis and whole-genome resequencing suggested that Yr85may be from a distant source.Moreover,agronomic trait evaluation indicated that Yr85 is located in a chromosomal region lacking linkage drag.Genotyping of 309 Chinese wheat cultivars and lines with a marker that cosegregated with Yr85 during fine mapping identified one cultivar possibly carrying the resistance gene.Our findings indicate that Yr85 has potential for use in wheat-breeding programs in China.This study lays the foundation for map-based cloning and marker-assisted selection of Yr85. 展开更多
关键词 Puccinia striiformis Disease resistance Genetic analysis Wheat breeding
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Efficacy and safety of fruquintinib plus sintilimab in third-line treatment of metastatic colorectal cancer:A single-center experience 认领 引用
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作者 Jun Pan Ping Li +5 位作者 Yi Zhao Yu-He Zhou Ying Zhao Tian-Long Zhang Yi-Tian Chen Xiao-Yuan Chu 《World Journal of Gastrointestinal Oncology》 SCIE 2026年第6期150-160,共11页
BACKGROUND There are few drugs available for the third-line treatment of metastatic colorectal cancer(mCRC),and efficacy is generally poor.Fruquintinib,an anti-vascular endothelial growth factor receptor tyrosine kina... BACKGROUND There are few drugs available for the third-line treatment of metastatic colorectal cancer(mCRC),and efficacy is generally poor.Fruquintinib,an anti-vascular endothelial growth factor receptor tyrosine kinase inhibitor,has been approved for mCRC;however,its efficacy as a single agent is not satisfactory.Most patients with mCRC are microsatellite stable(MSS),and not sensitive to immunotherapy.The combination of fruquintinib and immunotherapy may improve the survival of patients with mCRC.AIM To report the real-world experience using this combination therapy for MSS mCRC in routine clinical practice.METHODS The medical records of six patients with MSS mCRC who received third-line treatment with fruquintinib plus sintilimab between January 2022 and June 2024 were retrospectively reviewed.Survival analysis was performed using the Kaplan-Meier method.RESULTS One patient achieved a complete response,one had stable disease,and four experienced progressive disease.Median progression-free survival was 3.8 months,and median overall survival was 5.7 months.Common adverse reactions included bone marrow suppression,liver function impairment,and hypothyroidism,predominantly grades 1-2,with no grade 4 adverse reactions reported.CONCLUSION Our single-center experience in a small cohort implies fruquintinib combined with sintilimab may be efficacious and safe for select patients in the third-line treatment of mCRC.This combination therapy warrants further exploration. 展开更多
关键词 Metastatic colorectal cancer Third-line treatment Fruquintinib Sintilimab Immunotherapy Prognosis
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Impact of B alloying on ductility and phase transition in the Ni–Mn-based magnetic shape memory alloys:Insights from first-principles calculation 认领 引用 被引量:6
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作者 Hai-Le Yan Hao-Xuan Liu +8 位作者 Ying Zhao Nan Jia Jing Bai Bo Yang Zongbin Li Yudong Zhang Claude Esling Xiang Zhao Liang Zuo 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2021年第15期27-34,共8页
Brittleness is a bottleneck hindering the applications of fruitful functional properties of Ni–Mn-based multiferroic alloys.Recently,experimental studies on B alloying shed new light on this issue.However,the knowled... Brittleness is a bottleneck hindering the applications of fruitful functional properties of Ni–Mn-based multiferroic alloys.Recently,experimental studies on B alloying shed new light on this issue.However,the knowledge related to B alloying is limited until now.More importantly,the mechanism of the improved ductility,which is intrinsically related to the chemical bond that is difficult to reveal by routine experiments,is still unclear.In this context,by first-principles calculations,the impact and the correlated mechanism of B alloying were systemically studied by investigating four alloying systems,i.e.,(Ni2-xBx)MnGa,Ni2(Mn1-xBx)Ga,Ni2Mn(Ga1-xBx)and(Ni2MnGa)1-xBx.Results show that B prefers the direct occupation manner when it replaces Ni,Mn and Ga.For interstitial doping,B tends to locate at octahedral rather than tetrahedral interstice.Calculations show that the replacement of B for Ga can effectively improve(reduce)the inherent ductility(inherent strength)due to the weaker covalent strength of Ni(Mn)–B compared with Ni(Mn)–Ga.In contrast,B staying at octahedral interstice will lead to the formation of new chemical bonds between Ni(Mn)and B,bringing about a significantly improved strength and a greatly reduced ductility.Upon the substitutions for Ni and Mn,they affect both the inherent ductility and strength insignificantly.For phase transition,the replacement of B for Ga tends to destabilize the austenite,which can be understood in the picture of the band Jahn–Teller effect.Besides,the substitution for Ga would not lead to an obvious reduction of magnetization. 展开更多
关键词 Magnetic shape memory alloys Boron alloying Ductility Phase stability First-principles calculation
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From ancient herb to modern miracle:an in-depth analysis of the cardioprotective effects of artemisinin and its derivatives 认领 引用
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作者 Hao-Shuang LI Shu-Rong LI +6 位作者 Wen-Jue LIU Yuan ZHANG Rui WU Xu-Yang CUI Jia-Zheng SUN You-Wei MA Ying ZHAO 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2026年第1期45-64,共20页
Significant progress has been recently made in studying artemisinin and its derivatives for treating cardiovascular diseases,making this area a prominent research focus.Artemisinin,discovered with great acclaim,was in... Significant progress has been recently made in studying artemisinin and its derivatives for treating cardiovascular diseases,making this area a prominent research focus.Artemisinin,discovered with great acclaim,was initially and widely adopted in antimalarial treatments.As scientific research steadily progressed,its latent potential role in the cardiovascular system gradually captured the attention of the global scientific community.Artemisinin and its derivatives can reportedly play a protective role in the cardiovascular system through various mechanisms,including anti-inflammatory,anti-angiogenic,antioxidant,and anti-fibrotic effects,as well as the regulation of blood lipids and blood pressure.In particular,they have shown promising therapeutic effects in models of cardiovascular diseases such as atherosclerosis,myocardial ischaemia,and cardiac hypertrophy.In addition,artemisinin and its derivatives can improve cardiovascular function and prevent cardiovascular injury by regulating signalling pathways closely related to cardiovascular disease,such as AMPK and NF-kB.Although numerous ex vivo and in vivo experiments have verified the potential role of artemisinin in treating cardiovascular diseases,systematic studies to comprehensively elucidate its specific mechanism of action remain scarce.Further exploration of the precise roles of artemisinin and its derivatives in cardiovascular disease therapy,along with their potential clinical applications,could offer valuable insights for future research and treatment strategies. 展开更多
关键词 antimalarial treatmentsas artemisinin cardiovascular diseasesmaking myocardial ischemia cardiac hypertrophy cardiovascular system cardioprotective effects atherosclerosis
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Crystallization kinetics modulation for efficient inverted inorganic perovskite solar cells 认领 引用
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作者 Jiahui Li Jianlong Chang +4 位作者 Yali Liu Shanshan Qi Pengyang Wang Ying Zhao Xiaodan Zhang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第2期513-520,I0012,共8页
Inorganic perovskite solar cells(IPSCs),due to their suitable bandgap and superior thermal stability,are ideal candidates for tandem solar cells combined with silicon.However,the development of inorganic perovskite so... Inorganic perovskite solar cells(IPSCs),due to their suitable bandgap and superior thermal stability,are ideal candidates for tandem solar cells combined with silicon.However,the development of inorganic perovskite solar cells has been hindered by suboptimal crystallization dynamics that generate detrimental defects in the perovskite lattice.Here,we propose 4-Methoxyphenylphosphonic Acid(4MPA)as a multifunctional additive to address this challenge.P=O in 4MPA establish strong coordination with undercoordinated Pb2+,while-OH engage in O...H-O hydrogen bonding interactions with DMSO,effectively weakening the solvent-[PbX6]4-octahedron interaction.This dual functionality facilitates complete and rapid DMA+-to-Cs+cation exchange while regulating crystallization kinetics,thereby optimizing crystal growth.Furthermore,π-π interactions between benzene rings significantly enhance the moisture resistance of the perovskite layer.The optimized device demonstrates a power conversion efficiency(PCE)of 21.35%,with unencapsulated devices retaining 93,63%of their initial efficiency after 200-hour continuous operation under ambient conditions(35%relative humidity). 展开更多
关键词 Inverted inorganic perovskite solar cells Crystallization kinetics Dual function Additive engineering
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Random finite element analysis on ground subsidence caused by tunnel excavation in karst regions with spatial variable soil 认领 引用
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作者 Zhenghong Su Yong Fu +2 位作者 Miaomiao Sun Kailin Ding Ying Zhao 《Deep Underground Science and Engineering》 EI CAS CSCD 2026年第2期615-632,共18页
The construction of tunnels inevitably leads to ground subsidence,while surface collapses caused by caverns during excavation can result in significant financial losses.However,previous research on tunnel excavation b... The construction of tunnels inevitably leads to ground subsidence,while surface collapses caused by caverns during excavation can result in significant financial losses.However,previous research on tunnel excavation behavior in karst areas has predominantly assumed uniform soil strength,neglecting the geological uncertainty arising from soil spatial variability and rarely discussing the combined effects of soil variability and geological construction conditions.Therefore,this study conducted a series of random finite element analyses to investigate ground subsidence during tunnel excavation in karst cave areas,considering the combined effects of different karst cave distances and sizes as well as soil spatial variability.It was found that shorter distances between the cavern and the tunnel resulted in greater shifts in subsided trench toward the sides of the cavern.Furthermore,larger cavern diameters amplified the effect of geological variability on soils,leading to increased dispersion of maximum ground subsidence.Ground subsistence also showed sensitivity to changes in soil modulus with the coefficient of variation(COV).Neglecting cave influences could potentially underestimate failure probabilities.Additionally,three patterns for surface subsidence were presented based on different geological conditions.Finally,this study proposed a modified Peck formula to predict ground subsidence during tunnel excavation considering the combined effects of karst cave and soil spatial variability,which may enhance current design methods for tunnel engineering. 展开更多
关键词 ground subsidence karst cave probabilistic analysis soil spatial variability tunnel excavation
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The enhancements of pore morphology and size distribution by straw return are mediated by increases in aggregate-associated carbon and nitrogen 认领 引用 被引量:4
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作者 Ying Zhao Xiaozeng Han +4 位作者 Chen Qiu Wenxiu Zou Xinchun Lu Jun Yan Xu Chen 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2025年第4期1562-1576,共15页
The accumulation of soil organic carbon(SOC)and total nitrogen(TN)is easily accomplished by returning crop straw,which strongly affects the formation and pore structure of aggregates,especially in black soil.We return... The accumulation of soil organic carbon(SOC)and total nitrogen(TN)is easily accomplished by returning crop straw,which strongly affects the formation and pore structure of aggregates,especially in black soil.We returned maize straw at different rates(6,000,9,000,12,000 and 15,000 kg ha-1)for nine years to investigate its influence on the SOC and TN contents in the SOC fractions of aggregates by combining size and density fractionation.Their subsequent influences on pore morphology and size distribution characteristics were examined using X-ray microcomputed tomography scanning(μCT).The results showed that returning straw significantly increased the contents of C and N in the SOC fractions of aggregates,especially at the return rates of 12,000 and 15,000 kg ha-1,which in turn promoted aggregate formation and stability,and ultimately amended pore structure.The pore size>100μm,porosity(>2μm),and morphological characteristics(anisotropy,circularity,connectivity and fractal dimension)significantly increased,but the total number of pores significantly decreased(P<0.05).Our results indicated that the amendment of the pore morphology and size distribution of soil aggregates was primarily controlled by the higher contents of C and N in the density fractions of aggregates,rather than in the aggregate sizes.Furthermore,this pore network reconfiguration favored the storage of C and N simultaneously.The findings of this study offer valuable new insights into the relationships between C and N storage and the pore characteristics in soil aggregates under straw return. 展开更多
关键词 aggregate pore structure black soil density fractions water-stable aggregates X-ray micro-computed tomography
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Controllable self-assembly and photothermal conversion of metalla[2]catenanes induced by synergistic effect of free radicals and stacking interactions 认领 引用 被引量:3
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作者 Ying Zhao Yao He +6 位作者 Jian-Xin Yang Wen-Jie Liu Dan Tian Francisco Aznarez Le-Le Gong Li-Long Dang Lu-Fang Ma 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第12期186-192,共7页
The self-assembly and photothermal application studies of interlocked compounds has been attracting increasing attention during the last decades.Nevertheless,the synthesis of a series of interlocked topologies possess... The self-assembly and photothermal application studies of interlocked compounds has been attracting increasing attention during the last decades.Nevertheless,the synthesis of a series of interlocked topologies possessing similar structural characteristic and clarifying their photothermal performance law remains a challenge.Herein,we introduce a new dipyridinyl ligand L1 featuring two methoxy groups,which act as electron-donating species and provide electrons to the central benzene ring,resulting in an enhanced electron rich effect.Previous research indicates that this feature significantly contributes to forming π-stacking interactions.Furthermore,four half-sandwich rhodium-based building blocks exhibiting different metal-to-metal distances and conjugated effect were selected and used to combine with L1 for the synthesis of[2]catenanes and metallamacrocycles for studying the influence of half-sandwich building blocks on photothermal conversion performance under the same accumulation effect.Three new metalla[2]catenanes and one metallamacrocycle have been obtained in high yields and their structure has been unambiguously confirmed by single crystal X-ray diffraction analysis,NMR spectroscopy,and ESI-TOF-MS.In addition,dynamic structural transformation between[2]catenanes and the corresponding metallamacrocycles has been observed through concentration changes and polar solvent induced effect.Photothermal conversion abilities of the isolated complexes were studied and we observed that[2]catenane 3a displayed significant temperature changes(from 25.8℃ to 50.3℃)under laser irradiation of 1.5 W/cm2,thereby reaching a photothermal conversion efficiency of 40.42%.Recorded EPR data indicates that the synergistic cooperation of the free radical effect at the building unit and the stacking effect of[2]catenanes most likely generated photothermal conversion. 展开更多
关键词 catenanes Structural transformation Coordination-driven self-assembly Supramolecular topologies Photothermal conversion
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Effect of macrophage- to- myofibroblast transition on silicosis 认领 引用 被引量:3
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作者 Fei Geng Jingrou Xu +12 位作者 Xichen Ren Ying Zhao Yuhao Cai Yaqian Li Fuyu Jin Tian Li Xuemin Gao Wenchen Cai Hong Xu Zhongqiu Wei Na Mao Ying Sun Fang Yang 《Animal Models and Experimental Medicine》 CAS CSCD 2025年第2期363-371,共9页
Background:The aim was to explore the effect of macrophage polarization and macrophage-to-myofibroblast transition(MMT)in silicosis.Methods:Male Wistar rats were divided into a control group and a silicosis group deve... Background:The aim was to explore the effect of macrophage polarization and macrophage-to-myofibroblast transition(MMT)in silicosis.Methods:Male Wistar rats were divided into a control group and a silicosis group developed using a HOPE MED 8050 dynamic automatic dusting system.Murine mac-rophage MH-S cells were randomly divided into a control group and an SiO2 group.The pathological changes in lung tissue were observed using hematoxylin and eosin(HE)and Van Gieson(VG)staining.The distribution and location of macrophage marker(F4/80),M1 macrophage marker(iNOS),M2 macrophage marker(CD206),and myofibroblast marker(α-smooth muscle actin[α-SMA])were detected using immu-nohistochemical and immunofluorescent staining.The expression changes in iNOS,Arg,α-SMA,vimentin,and type I collagen(Col I)were measured using Western blot.Results:The results of HE and VG staining showed obvious silicon nodule formation and the distribution of thick collagen fibers in the lung tissue of the silicosis group.Macrophage marker F4/80 increased gradually from 8 to 32 weeks after exposure to silica.Immunohistochemical and immunofluorescent staining results revealed that there were more iNOS-positive cells and some CD206-positive cells in the lung tissue of the silicosis group at 8 weeks.More CD206-positive cells were found in the silicon nodules of the lung tissues in the silicosis group at 32 weeks.Western blot analysis showed that the expressions of Inducible nitric oxide synthase and Arg protein in the lung tissues of the silicosis group were upregulated compared with those of the con-trol group.The results of immunofluorescence staining showed the co-expression of F4/80,α-SMA,and Col I,and CD206 andα-SMA were co-expressed in the lung tissue of the silicosis group.The extracted rat alveolar lavage fluid revealed F4/80+α-SMA+,CD206+α-SMA+,and F4/80+α-SMA+Col I+cells using immunofluorescence staining.Similar results were also found in MH-S cells induced by SiO2.Conclusions:The development of silicosis is accompanied by macrophage polarization and MMT. 展开更多
关键词 macrophage macrophage-to-myofibroblast transition silicosis
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Flexible molecules dedicate to release strain of inverted inorganic perovskite solar cell 认领 引用 被引量:1
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作者 Hongrui Sun Sanlong Wang +5 位作者 Pengyang Wang Yali Liu Shanshan Qi Biao Shi Ying Zhao Xiaodan Zhang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2025年第1期87-93,共7页
The tensile strain in inorganic perovskite films induced by thermal annealing is one of the primary factors contributing to the inefficiency and instability of inorganic perovskite solar cells(IPSCs),which reduces the... The tensile strain in inorganic perovskite films induced by thermal annealing is one of the primary factors contributing to the inefficiency and instability of inorganic perovskite solar cells(IPSCs),which reduces the defect formation energy.Here,a flexible molecule 5-maleimidovaleric acid(5-MVA)was introduced as a strain buffer to release the residual strain of CsPbI2.85Br0.15perovskite.Maleic anhydride and carboxyl groups in 5-MVA interact strongly with the uncoordinated Pb2+through Lewis acid-base reaction,thus tightly“pull”the perovskite lattice.The in-between soft carbon chain increased the structural flexibility of CsPbI2.85Br0.15perovskite materials,which effectively relieved the intrinsic internal strain of CsPbI2.85Br0.15,resisted the corrosion of external strain,and also reduced the formation of defects such as VIand Pb0.In addition,the introduction of 5-MVA improved crystal quality,passivated residual defects,and narrowed energy level barriers.Eventually,power conversion efficiency(PCE)of NiOxbased inverted IPSCs increased from 19.25%to 20.82%with the open-circuit voltage enhanced from 1.164 V to 1.230 V.The release of strain also improved the stability of CsPbI2.85Br0.15perovskite films and devices. 展开更多
关键词 Inverted inorganic perovskite solar cells Flexible molecules Strain release Crystallization Energy barrier High PCE
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Genome-wide characterization of soybean malate dehydrogenase genes reveals a positive role for GmMDH2 in the salt stress response 认领 引用 被引量:1
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作者 Runnan Zhou Sihui Wang +9 位作者 Peiyan Liu Yifan Cui Zhenbang Hu Chunyan Liu Zhanguo Zhang Mingliang Yang Xin Li Xiaoxia Wu Qingshan Chen Ying Zhao 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2025年第7期2492-2510,共19页
Malate dehydrogenase(MDH)is a widely expressed enzyme that plays a key role in plant growth,development,and stress responses.However,information on MDH genes in the soybean genome is limited.Seventeen members of the s... Malate dehydrogenase(MDH)is a widely expressed enzyme that plays a key role in plant growth,development,and stress responses.However,information on MDH genes in the soybean genome is limited.Seventeen members of the soybean MDH family were identified by genome-wide analysis,and the genes were analyzed for the presence of conserved protein motifs.The genes were divided into five clusters according to their phylogenetic relationships.The intracellular localizations of six GmMDHs were determined by confocal microscopy of Arabidopsis mesophyll protoplasts.Transcripts of GmMDHs were significantly increased by abiotic stress(drought,salt,and alkalinity)and hormone treatments,as shown by an analysis of cis-regulatory elements and quantitative real-time polymerase chain reaction(qRT-PCR).The GmMDHs displayed unique expression patterns in various soybean tissues.Notably,the expression levels of a chloroplast isoform(GmMDH2)were unusually high under salt stress,presumably indicating a critical role in soybean responses to salinity.Expression of GmMDH2 in Escherichia coli showed that the recombinant enzyme has nicotinamide adenine dinucleotide phosphate(NADP)-dependent MDH activity.The redox states of the NADP(reduced form)(NADPH)pool and antioxidant activities were shown to be modulated by GmMDH2 gene overexpression,which in turn reduced reactive oxygen species(ROS)formation in transgenic soybean,significantly enhancing the salt stress resistance.Gene-based association analysis showed that variations in GmMDH2 were strongly linked to seedling salt tolerance.A polymorphism potentially associated with salt tolerance was discovered in the promoter region of GmMDH2.These findings not only improve our understanding of the stress response mechanism by identifying and characterizing the MDH gene family throughout the soybean genome but they also identified a potential candidate gene for the future enhancement of salt tolerance in soybean. 展开更多
关键词 soybean(Glycine max(Linn.)Merr.) malate dehydrogenase expression profile salt stress
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Inhibition of KLK8 promotes pulmonary endothelial repair by restoring the VE-cadherin/Akt/FOXM1 pathway 认领 引用
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作者 Ying Zhao Hui Ji +10 位作者 Feng Han Qing-Feng Xu Hui Zhang Di Liu Juan Wei Dan-Hong Xu Lai Jiang Jian-Kui Du Ping-Bo Xu Yu-Jian Liu Xiao-Yan Zhu 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2025年第4期870-872,共3页
Repairing the endothelial barrier is essential for maintaining pulmonary fuid balance and regulating leukocyte infiltration during sepsis[1].Tissue kallikrein-related peptidases(KLKs)are secreted serine proteases invo... Repairing the endothelial barrier is essential for maintaining pulmonary fuid balance and regulating leukocyte infiltration during sepsis[1].Tissue kallikrein-related peptidases(KLKs)are secreted serine proteases involved in angiogenesis[2].However,their involvement in regulating endothelial regeneration remains largely unknown. 展开更多
关键词 repairing endothelial barrier regulating leukocyte infiltration pulmonary endothelial repair inhibition klk ve cadherin maintaining pulmonary fuid balance serine proteases
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Clinical characteristics and prognostic analysis of three hundred and nineteen cases of primary gastrointestinal diffuse large B-cell lymphoma 认领 引用
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作者 Jia-Jia Ma Huan Zhang +3 位作者 Cui-Cui Wang Wen-Li Ji Ying Zhao Xin-Xia Li 《World Journal of Gastrointestinal Oncology》 SCIE 2025年第12期157-168,共12页
BACKGROUND Primary gastrointestinal diffuse large B-cell lymphoma(PGI-DLBCL),the most prevalent extranodal non-Hodgkin lymphoma,poses significant diagnostic and therapeutic challenges due to its non-specific symptoms ... BACKGROUND Primary gastrointestinal diffuse large B-cell lymphoma(PGI-DLBCL),the most prevalent extranodal non-Hodgkin lymphoma,poses significant diagnostic and therapeutic challenges due to its non-specific symptoms and poor prognosis.AIM To develop and validate a risk model for the early identification of PGI-DLBCL using Least Absolute Shrinkage and Selection-Cox regression,with the aim of guiding clinical decision-making.METHODS The clinical data of patients diagnosed with PGI-DLBCL at the Tumor Hospital Affiliated to Xinjiang Medical University were analyzed retrospectively from January 2010 to April 2022.RESULTS A total of 319 patients with PGI-DLBCL were included and divided into training(n=223)and validation(n=96)cohorts.The median age was 55 years,with 48.9%male and 51.1%female patients.Key clinical features included Eastern Cooperative Oncology Group performance status≥2(40.8%),advanced-stage disease(stage IV:27.6%),extranodal involvement≥2 sites(47%),tumor>5 cm(46.1%),elevated beta-2 microglobulin(50.5%),elevated lactate dehydrogenase(27%),high International Prognostic Index(3-5:69.9%),non-germinal center B-cell-like subtype(59.9%),and B symptoms(55.8%).Immunohistochemical analysis showed frequent expression of CD10(51.1%),B-cell lymphoma 6(53.3%),multiple myeloma oncogene 1(40.1%),Bcell lymphoma 2(49.2%),myelocytomatosis viral oncogene homolog(48.3%),Ki-67(67.1%),and CD5(42.6%);Epstein-Barr virus-encoded RNA was positive in 3.1%.Based on Least Absolute Shrinkage and Selection regression and subsequent univariate and multivariate Cox regression analyses,extranodal sites≥2,B symptoms,mixed lesion type,and negative multiple myeloma oncogene 1 expression were identified as independent risk factors for PGI-DLBCL.The risk model stratified patients into high-and low-risk groups with significantly different overall survival(P<0.05).Area under the curve values for 1-,3-,and 5-year overall survival were 0.625,0.663,and 0.723 in the training cohort,with consistent performance in the validation cohort.Decision curve analysis indicated favorable clinical utility.CONCLUSION PGI-DLBCL in our cohort showed distinctive clinical features and a predominance of the non-germinal center Bcell-like subtype.Decision curve analysis confirmed the clinical applicability of our prognostic model.Although molecular biomarkers will be needed to improve predictive precision,our model offers a practical tool for early risk identification and individualized management in clinical practice. 展开更多
关键词 Primary gastrointestinal diffuse large B-cell lymphoma Clinical characteristics Risk model Non-germinal center B-cell-like subtype Survival analysis Prognosis
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Graph visualization efficiency of popular web‑based libraries 认领 引用
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作者 Xin Zhao Xuan Wang +6 位作者 Xianzhe Zou Huiming Liang Genghuai Bai Ning Zhang Xin Huang Fangfang Zhou Ying Zhao 《Visual Computing for Industry,Biomedicine,and Art》 EI 2025年第1期194-210,共17页
Web-based libraries,such as D3.js,ECharts.js,and G6.js,are widely used to generate node-link graph visualizations.These libraries allow users to call application programming interfaces(APIs)without identifying the det... Web-based libraries,such as D3.js,ECharts.js,and G6.js,are widely used to generate node-link graph visualizations.These libraries allow users to call application programming interfaces(APIs)without identifying the details of the encapsulated techniques such as graph layout algorithms and graph rendering methods.Efficiency requirements,such as visualizing a graph with 3k nodes and 4k edges within 1 min at a frame rate of 30 fps,are crucial for selecting a proper library because libraries generally present different characteristics owing to the diversity of encapsulated techniques.However,existing studies have mainly focused on verifying the advantages of a new layout algorithm or rendering method from a theoretical viewpoint independent of specific web-based libraries.Their conclusions are difficult for end users to understand and utilize.Therefore,a trial-and-error selection process is required.This study addresses this gap by conducting an empirical experiment to evaluate the performance of web-based libraries.The experiment involves popular libraries and hundreds of graph datasets covering node scales from 100 to 200k and edge-to-node ratios from 1 to 10(including complete graphs).The experimental results are the time costs and frame rates recorded using the libraries to visualize the datasets.The authors analyze the performance characteristics of each library in depth based on the results and organize the results and findings into application-oriented guidelines.Additionally,they present three usage cases to illustrate how the guidelines can be applied in practice.These guidelines offer user-friendly and reliable recommendations,aiding users in quickly selecting the desired web-based libraries based on their specific efficiency requirements for node-link graph visualizations. 展开更多
关键词 Graph visualization Node-link diagram Web-based visualization Visualization library
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