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Development of an antenna adjustable fundamental power coupler for the 81.25 MHz superconducting cavity at the High Intensity Heavy‑Ion Accelerator Facility 认领 引用
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作者 Guo‑Chang Liu Tian‑Cai Jiang +9 位作者 Zong‑Heng Xue Ji‑Yu Wang Ke‑An Jin Meng‑Xin Xu Zhou‑Li Zhang Chun‑Long Li Qi‑Tong Huang Sheng‑Xue Zhang Sheng‑Hu Zhang Yuan He 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2026年第7期1-17,共17页
The Institute of Modern Physics(IMP)of the Chinese Academy of Sciences(CAS)has designed and prototyped fundamental power couplers for 81.25 MHz superconducting quarter-wave resonators(QWR)in the High-Intensity Heavy-I... The Institute of Modern Physics(IMP)of the Chinese Academy of Sciences(CAS)has designed and prototyped fundamental power couplers for 81.25 MHz superconducting quarter-wave resonators(QWR)in the High-Intensity Heavy-Ion Accelerator Facility(HIAF).The QWR coupler operates in the pulsed or continuous-wave mode with an average power of 6 kW.This coupler is designed with a 50Ωcoaxial structure and a dual-disk warm-window assembly.Focusing on the optimized heat leakage,a double-walled structure is applied to the outer conductor of the coupler for helium gas cooling at 5 K.To suppress multipacting(MP),a 10-nm titanium nitride(TiN)coating is applied to the vacuum side of the ceramic window,whereas a DC bias voltage is applied to the inner conductor.To reduce the production cost of the coupler and make it suitable for mass production,various coupler fabrication materials were tested,and the feasibility of the fabrication process was verified.The coupler includes two types of diagnostic ports for vacuum and ARC monitoring.Two prototype couplers were fabricated and tested for high-power conditioning.The QWR couplers proved their robustness with 10 h of 9 kW traveling-wave conditioning and 12 h of 9 kW standing wave conditioning,achieving a stabilized 9 kW power level and a stable vacuum.As predicted,MP barriers were encountered at input powers ranging from 1 kW to 9 kW,and a DC bias voltage of 800 V effectively suppressed the occurrence of MP. 展开更多
关键词 81.25 MHz fundamental power coupler Superconducting quarter-wave resonator High-power conditioning
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Conceptual design of the muonium-to-antimuonium conversion experiment(MACE) 认领 引用
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作者 Ai-Yu Bai Han-Jie Cai +49 位作者 Chang-Lin Chen Si-Yuan Chen Xu-Rong Chen Yu Chen Wei-Bin Cheng Ling-Yun Dai Rui-Rui Fan Li Gong Zi-Hao Guo Yuan He Zhi-Long Hou Yin-Yuan Huang Huan Jia Hao Jiang Han-Tao Jing Xiao-Shen Kang Hai-Bo Li Jin-Cheng Li Yang Li Da-Ming Liu Shu-Lin Liu Gui-Hao Lu Han Miao Yun-Song Ning Jian-Wei Niu Hua-Xing Peng Alexey APetrov Yuan-Shuai Qin Ming-Chen Sun Jian Tang Jing-Yu Tang Ye Tian Rong Wang Xiao-Dong Wang Yi Wang Zhi-Chao Wang Chen Wu Tian-Yu Xing Wei-Zhi Xiong Yu Xu Bao-Jun Yan De-Liang Yao Tao Yu Ye Yuan Yi Yuan Yao Zhang Yongchao Zhang Zhi-Lv Zhang Guang Zhao Shi-Han Zhao 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2026年第4期139-187,共49页
The spontaneous conversion of muonium to antimuonium is an interesting charged lepton flavor violation phenomenon that offers a sensitive probe for potential new physics and serves as a tool to constrain the parameter... The spontaneous conversion of muonium to antimuonium is an interesting charged lepton flavor violation phenomenon that offers a sensitive probe for potential new physics and serves as a tool to constrain the parameter space beyond the Standard Model.The Muonium-to-Antimuonium Conversion Experiment(MACE)was designed to utilize a high-intensity muon beam,a Michel electron magnetic spectrometer,a positron transport system,and a positron detection system to either discover or constrain this rare process with a conversion probability of O(10-13).This article presents an overview of the theoretical framework and a detailed description of the experimental design for muonium-to-antimuonium conversion. 展开更多
关键词 Muonium Lepton flavor violation Muon beam Drift chamber Microchannel plate Electromagnetic calorimeter
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Differences of the lamina cribrosa between primary open angle glaucoma and non-pathologic high myopia 认领 引用
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作者 Qing-Qing Mu Ping Ge +7 位作者 Xu Liu Jun Jia Na Cui Xiang-Xiang Yang Rui-Xue Zhang Yan Liu Yuan-Yuan Zhang Yuan He 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第6期1177-1185,共9页
Primary open angle glaucoma(POAG)is a chronic,blinding ocular disorder characterized by progressive degeneration of retinal ganglion cells(RGCs).Its incidence and prevalence of blindness continue to increase with glob... Primary open angle glaucoma(POAG)is a chronic,blinding ocular disorder characterized by progressive degeneration of retinal ganglion cells(RGCs).Its incidence and prevalence of blindness continue to increase with global population aging.Non-pathologic high myopia(HM)has been established as an independent risk factor for POAG,and the two conditions share similar structural changes in the lamina cribrosa(LC)during the early phase of optic nerve injury.This review summarizes the common and distinct pathological alterations of LC in POAG and HM,with the aim of clarifying its central role in the initiation and progression of optic nerve damage.Elucidating these similarities and differences may facilitate early detection and targeted intervention strategies for at-risk individuals from a structural perspective. 展开更多
关键词 non-pathologic high myopia primary open angle glaucoma optic disc lamina cribrosa retinal nerve fiber layer
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Expert consensus on the prevention and treatment of radiochemotherapy-induced oral mucositis 认领 引用 被引量：4
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作者 Juan Xia Xiaoan Tao +29 位作者 Qinchao Hu Wei Luo Xiuzhen Tong Gang Zhou Hongmei Zhou Hong Hua Guoyao Tang Tong Wu Qianming Chen Yuan Fan Xiaobing Guan Hongwei Liu Chaosu Hu Yongmei Zhou Xuemin Shen Lan Wu Xin Zeng Qing Liu Renchuan Tao Yuan He Yang Cai Wenmei Wang Ying Zhang Yingfang Wu Minhai Nie Xin Jin Xiufeng Wei Yongzhan Nie Changqing Yuan Bin Cheng 《International Journal of Oral Science》 SCIE CAS CSCD 2025年第5期617-630,共14页
Radiochemotherapy-induced oral mucositis(OM)is a common oral complication in patients with tumors following head and neck radiotherapy or chemotherapy.Erosion and ulcers are the main features of OM that seriously affe... Radiochemotherapy-induced oral mucositis(OM)is a common oral complication in patients with tumors following head and neck radiotherapy or chemotherapy.Erosion and ulcers are the main features of OM that seriously affect the quality of life of patients and even the progress of tumor treatment.To date,differences in clinical prevention and treatment plans for OM have been noted among doctors of various specialties,which has increased the uncertainty of treatment effects.On the basis of current research evidence,this expert consensus outlines risk factors,clinical manifestations,clinical grading,ancillary examinations,diagnostic basis,prevention and treatment strategies and efficacy indicators for OM.In addition to strategies such as basic oral care,antiinflammatory and analgesic agents,anti-infective agents,pro-healing agents,and photobiotherapy recommended in previous guidelines,we also emphasize the role of traditional Chinese medicine in OM prevention and treatment.This expert consensus aims to provide references and guidance for dental physicians and oncologists in formulating strategies for OM prevention,diagnosis,and treatment,standardizing clinical practice,reducing OM occurrence,promoting healing,and improving the quality of life of patients. 展开更多
关键词 treatment current research evidence oral mucositis om oral care head neck radiotherapy ulcers radiochemotherapy induced oral mucositis oral complication
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Petrogenesis of the Dengying Formation Dolomite in Northeast Sichuan Basin,SW China:Constraints from Carbon-Oxygen Isotopic and Trace Elemental Data 认领 引用 被引量：2
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作者 Yuan He Wenqi Li +6 位作者 Huichuan Liu Nansheng Qiu Kunyu Li Cheng Xi Xiaoliang Bai Hongyu Long Youlian Chen 《Journal of Earth Science》 SCIE CAS CSCD 2025年第1期75-88,共14页
The widespread dolomite of the Sinian Dengying Formation in the Sichuan Basin(China)serves as one of the most important oil and gas reservoir rocks of the basin.Well WT1,as an exploration well,is recently drilled in t... The widespread dolomite of the Sinian Dengying Formation in the Sichuan Basin(China)serves as one of the most important oil and gas reservoir rocks of the basin.Well WT1,as an exploration well,is recently drilled in the Kaijiang County,northeastern Sichuan Basin(SW China),and it drills through the Dengying Formation dolomite at the depth interval of 7500–7580 m.In this study,samples are systematically collected from the cores of that interval,followed by new analyses of carbon-oxygen isotope,major elements,trace elements,rare earth elements(REEs)and EP-MA.The Dengying Formation dolomites of Well WT1 haveδ13C values of 0.37‰to 2.91‰andδ18O values of-5.72‰to-2.73‰,indicating that the dolomitization fluid is derived from contemporary seawater in the near-surface environment,rather than the burial environment.Based on the REE patterns of EPMA-based in-situ data,we recognized the seawater-sourced components,the mixedsourced components and the terrigenous-sourced components,indicating the marine origin of the dolomite with detrital contamination and diagenetic alteration.Moreover,high Al,Th,and Zr contents indicate significant detrital contamination derived from clay and quartz minerals,and high Sr/Ba and Sr/Cu ratios imply a relatively dry depositional environment with extremely high seawater salinity,intensive evaporation,and strong influences of terrigenous sediment. 展开更多
关键词 Sichuan Basin Dengying Formation dolomite carbon-oxygen isotope EPMA
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Exploration of the copper–niobium composite superconducting cavities for pursuing extremely high operational stability at IMP 认领 引用 被引量：1
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作者 Shi-Chun Huang Yuan He +16 位作者 Long Peng Chun-Long Li Sheng-Xue Zhang Meng-Xin Xu Zi-Qin Yang Hao Guo Lu-Bei Liu Ping-Ran Xiong An-Dong Wu Qing-Wei Chu Xiao-Fei Niu Teng Tan Zhi-Jun Wang Jun-Hui Zhang Sheng-Hu Zhang Hong-Wei Zhao Wen-Long Zhan 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2025年第5期19-29,共11页
Theoretically,copper–niobium(Cu-Nb)composite superconducting cavities have excellent potential for high thermal and mechanical stability.They can appropriately exploit the high-gradient surface processing recipes dev... Theoretically,copper–niobium(Cu-Nb)composite superconducting cavities have excellent potential for high thermal and mechanical stability.They can appropriately exploit the high-gradient surface processing recipes developed for the bulk niobium(Nb)cavity and the thick copper(Cu)layer’s high thermal conductivity and rigidity,thereby enhancing the operational stability of the bulk Nb cavities.This study conducted a global review of the technical approaches employed for fabricating Cu-Nb composite superconducting cavities.We explored Cu-Nb composite superconducting cavities based on two technologies at the Institute of Modern Physics,Chinese Academy of Sciences(IMP,CAS),including their manufacturing processes,radio-frequency(RF)characteristics,and mechanical performance.These cavities exhibit robust mechanical stability.First,the investigation of several 1.3 GHz single-cell elliptical cavities using the Cu-Nb composite sheets indicated that the wavy structure at the Cu-Nb interface influenced the reliable welding of the Cu-Nb composite parts.We observed the generation and trapping of magnetic flux density during the T_c crossing of Nb in cooldown process.The cooling rates during the T_c crossing of Nb exerted a substantial impact on the performance of the cavities.Furthermore,we measured and analyzed the surface resistance Rsattributed to the trapped magnetic flux induced by the Seebeck effect after quenching events.Second,for the first time,a low-beta bulk Nb cavity was plated with Cu on its outer surface using electroplating technology.We achieved a high peak electric field Epkof~88.8 MV/m at 2 K and the unloaded quality factor Q0at the Epkof 88.8 MV/m exceeded 1×1010.This demonstrated that the electroplating Cu on the bulk Nb cavity is a practical method of developing the Cu-Nb composite superconducting cavity with superior thermal stability.The results presented here provide valuable insights for applying Cu-Nb composite superconducting cavities in superconducting accelerators with stringent operational stability requirements. 展开更多
关键词 Superconducting radio-frequency cavities Cu-Nb composite Mechanical and thermal stability Thermoelectrical effect Magnetic flux trapping effect
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Failure mechanisms of AlGaN/GaN HEMTs irradiated by high-energy heavy ions with and without bias 认领 引用 被引量：2
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作者 Pei-Pei Hu Li-Jun Xu +9 位作者 Sheng-Xia Zhang Peng-Fei Zhai Ling Lv Xiao-Yu Yan Zong-Zhen Li Yan-Rong Cao Xue-Feng Zheng Jian Zeng Yuan He Jie Liu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2025年第1期49-58,共10页
Gallium nitride(GaN)-based devices have significant potential for space applications.However,the mechanisms of radiation damage to the device,particularly from strong ionizing radiation,remains unknown.This study inve... Gallium nitride(GaN)-based devices have significant potential for space applications.However,the mechanisms of radiation damage to the device,particularly from strong ionizing radiation,remains unknown.This study investigates the effects of radiation on p-gate AlGaN/GaN high-electron-mobility transistors(HEMTs).Under a high voltage,the HEMT leakage current increased sharply and was accompanied by a rapid increase in power density that caused"thermal burnout"of the devices.In addition,a burnout signature appeared on the surface of the burned devices,proving that a single-event burnout effect occurred.Additionally,degradation,including an increase in the on-resistance and a decrease in the breakdown voltage,was observed in devices irradiated with high-energy heavy ions and without bias.The latent tracks induced by heavy ions penetrated the heterojunction interface and extended into the GaN layer.Moreover,a new type of N2bubble defect was discovered inside the tracks using Fresnel analysis.The accumulation of N2bubbles in the heterojunction and buffer layers is more likely to cause leakage and failure.This study indicates that electrical stress accelerates the failure rate and that improving heat dissipation is an effective reinforcement method for GaN-based devices. 展开更多
关键词 GaN HEMTs Heavy ions Single-event burnout Latent tracks Degradation
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Online beam phase calibration with detuning compensation for normal-conducting cavities under closed-loop operation 认领 引用
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作者 Feng Qiu Cheng-Ye Xu +10 位作者 Ri-Hua Zeng Yuan He Shi-Hui Wei Jia-Yi Peng Li-Juan Yang Zi-Qin Yang Zhou-Li Zhang Zhi-Jun Wang Mu-Yuan Wang Cecilia Maiano Paolo Pierini 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2026年第6期15-30,共16页
Accurate calibration of the beam phase(i.e.,the phase of the beam arrival relative to the cavity accelerating field)is essential for maintaining the stability and efficiency of linear accelerators.Conventional offline... Accurate calibration of the beam phase(i.e.,the phase of the beam arrival relative to the cavity accelerating field)is essential for maintaining the stability and efficiency of linear accelerators.Conventional offline phase-scan methods,such as theΔT phase scan and phase-scan signature matching,are typically performed during commissioning or maintenance,requiring the accelerator to be taken out of normal operation.Moreover,these methods cannot effectively track the gradual drifts caused by ambient conditions.An online beam phase calibration technique using beam-induced radio-frequency(RF)transients was initially developed at DESY for superconducting cavities operating under open-loop conditions.Extending the DESY method to normal-conducting cavities at the European Spallation Source(ESS)introduces challenges.When the beam pulse length approaches the cavity time constantτ=1∕ω0.5,whereω0.5is the cavity half bandwidth,the detuning effects distort the trajectory of the beam-induced RF transient and degrade the beam phase measurement accuracy.Furthermore,open-loop operation is generally not advisable for high-current proton linacs because of stability and safety concerns associated with the operation.To address these issues,we revisited the cavity differential equations and proposed a detuning compensation method that corrects the distorted trajectory in the in-phase/quadrature plane of the laser beam.In addition,by analyzing the initial 1.4μs transient response before low-level RF(LLRF)feedback becomes active,beam phase calibration can be achieved under closed-loop operation.The experimental results indicate that the proposed method agrees well with beam position monitor(BPM)-based measurements.This approach enables real-time beam phase monitoring without interrupting the closed-loop operation and can be adapted to similar accelerator systems. 展开更多
关键词 Beam phase calibration Transient beam loading Detuning effect Closed-loop operation Low-level RF systems Normal-conducting cavity Particle accelerator
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Etiology and clinical analysis of secondary glaucoma:a single-center study from northwest China 认领 引用
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作者 Ying Liu Jie Yang +6 位作者 Rui-Xue Zhang Yao Lu Wei Sang Jin-Wei Xi Jun Jia Dan-Ping Guo Yuan He 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第1期69-76,共8页
AIM:To investigate the etiology and clinical characteristics of hospitalized secondary glaucoma(SG)patients in northwestern China.METHODS:A cross-sectional study was conducted involving SG patients hospitalized betwee... AIM:To investigate the etiology and clinical characteristics of hospitalized secondary glaucoma(SG)patients in northwestern China.METHODS:A cross-sectional study was conducted involving SG patients hospitalized between July 2024 and January 2025.Clinical data were collected,including medical history,best-corrected visual acuity(BCVA),intraocular pressure(IOP),slit-lamp examination,gonioscopic findings,and fundus examination.Demographic characteristics,etiological factors,and treatment modalities were analyzed.RESULTS:A total of 67 patients(82 eyes)were enrolled,aged 7 to 90y.Males accounted for 54.0%(36/67),and 22.4%(15/67)of patients had bilateral involvement.The predominant etiologies of SG were neovascular glaucoma(NVG;25.4%),traumatic glaucoma(23.9%),uveitic glaucoma(20.9%),and lens-induced glaucoma(14.9%),collectively accounting for 85.1%of all cases.The peak age-specific incidence occurred in the 50-59 years age group(32.8%,22/67),while NVG was prevalent across the 40-79 years age range.IOP of the 82 affected eyes was stratified into five severity tiers:22-29 mm Hg(15 eyes,18.3%),30-39 mm Hg(14 eyes,17.1%),40-49 mm Hg(13 eyes,15.9%),50-59 mm Hg(20 eyes,24.4%),and≥60 mm Hg(20 eyes,24.4%).The overall mean IOP was 45.2±12.3 mm Hg,indicating a significant pathological elevation.Surgical intervention was required in 46.3%of cases,predominantly for NVG,lensinduced glaucoma,and traumatic glaucoma—conditions prone to rapid IOP elevation.The etiologies with the highest surgical intervention rates were malignant glaucoma,pigmentary glaucoma,lens-induced glaucoma,and NVG.In contrast,uveitic glaucoma cases were primarily managed with targeted anti-inflammatory therapy,which effectively controlled IOP in the early disease stages and potentially obviated the need for surgery.CONCLUSION:This study identifies NVG,traumatic glaucoma,uveitic glaucoma,and lens-induced glaucoma as the four leading etiologies of SG in Northwestern China.These findings emphasize the critical need for targeted prevention strategies and evidence-based health education programs among high-risk populations.Implementation of such initiatives will improve early detection,enable ophthalmologists to deliver timely therapeutic interventions,and ultimately reduce preventable vision loss in this region. 展开更多
关键词 secondary glaucoma epidemiological northwestern China etiology
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Recurrent MAPPO for Joint UAV Trajectory and Traffic Offloading in Space-Air-Ground Integrated Networks 认领 引用 被引量：1
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作者 Zheyuan Jia Fenglin Jin +1 位作者 Jun Xie Yuan He 《Computers, Materials & Continua》 SCIE EI 2026年第1期447-461,共15页
This paper investigates the traffic offloading optimization challenge in Space-Air-Ground Integrated Networks(SAGIN)through a novel Recursive Multi-Agent Proximal Policy Optimization(RMAPPO)algorithm.The exponential g... This paper investigates the traffic offloading optimization challenge in Space-Air-Ground Integrated Networks(SAGIN)through a novel Recursive Multi-Agent Proximal Policy Optimization(RMAPPO)algorithm.The exponential growth of mobile devices and data traffic has substantially increased network congestion,particularly in urban areas and regions with limited terrestrial infrastructure.Our approach jointly optimizes unmanned aerial vehicle(UAV)trajectories and satellite-assisted offloading strategies to simultaneously maximize data throughput,minimize energy consumption,and maintain equitable resource distribution.The proposed RMAPPO framework incorporates recurrent neural networks(RNNs)to model temporal dependencies in UAV mobility patterns and utilizes a decentralized multi-agent reinforcement learning architecture to reduce communication overhead while improving system robustness.The proposed RMAPPO algorithm was evaluated through simulation experiments,with the results indicating that it significantly enhances the cumulative traffic offloading rate of nodes and reduces the energy consumption of UAVs. 展开更多
关键词 Space-air-ground integrated networks UAV traffic offloading reinforcement learning
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Genomic similarity and antibody-dependent enhancement of immune serum potentially affect the protective efficacy of commercial MLV vaccines against NADC30-like PRRSV 认领 引用 被引量：9
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作者 Yang Li Lele Xu +11 位作者 Dian Jiao Zifang Zheng Zhihao Chen Yang Jing Zhiwei Li Zhiqian Maa Yingtong Feng Xuyang Guo Yumiao Wang Yuan He Haixue Zheng Shuqi Xiao 《Virologica Sinica》 SCIE CAS CSCD 2023年第5期813-826,共14页
Porcine reproductive and respiratory syndrome(PRRS)is one of the most significant diseases affecting the pig industry worldwide.The PRRSV mutation rate is the highest among the RNA viruses.To date,NADC30-like PRRSV an... Porcine reproductive and respiratory syndrome(PRRS)is one of the most significant diseases affecting the pig industry worldwide.The PRRSV mutation rate is the highest among the RNA viruses.To date,NADC30-like PRRSV and highly pathogenic PRRSV(HP-PRRSV)are the dominant epidemic strains in China;however,commercial vaccines do not always provide sufficient cross-protection,and the reasons for insufficient protection are unclear.This study isolated a wild-type NADC30-like PRRSV,SX-YL1806,from Shaanxi Province.Vaccination challenge experiments in piglets showed that commercial modified live virus(MLV)vaccines provided good protection against HP-PRRSV.However,it could not provide sufficient protection against the novel strain SXYL1806.To explore the reasons for this phenomenon,we compared the genomic homology between the MLV strain and HP-PRRSV or NADC30-like PRRSV and found that the MLV strain had a lower genome similarity with NADC30-like PRRSV.Serum neutralization assay showed that MLV-immune serum slightly promoted the homologous HP-PRRSV replication and significantly promoted the heterologous NADC30-like PRRSV strain replication in vitro,suggesting that antibody-dependent enhancement(ADE)might also play a role in decreasing MLV protective efficacy.These findings expand our understanding of the potential factors affecting the protective effect of PRRSV MLV vaccines against the NADC30-like strains. 展开更多
关键词 NADC30-like PRRSV Modified live virus(MLV)vaccines Genomic similarity Antibody dependent enhancement(ADE) Cross protection
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Measurement of the cavity-loaded quality factor in superconducting radio-frequency systems with mismatched source impedance 认领 引用 被引量：7
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作者 Jin-Ying Ma Cheng-Ye Xu +12 位作者 An-Dong Wu Guo-Dong Jiang Yue Tao Zong-Heng Xue Long-Bo Shi Tian-Cai Jiang Zheng-Long Zhu Zi-Qin Yang Zheng Gao Lie-Peng Sun Gui-Rong Huang Feng Qiu Yuan He 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第8期12-23,共12页
The accurate measurement of parameters such as the cavity-loaded quality factor(QL)and half bandwidth(f0.5)is essential for monitoring the performance of superconducting radio-frequency cavities.However,the conv... The accurate measurement of parameters such as the cavity-loaded quality factor(QL)and half bandwidth(f0.5)is essential for monitoring the performance of superconducting radio-frequency cavities.However,the conventional"field decay method"employed to calibrate these values requires the cavity to satisfy a"zero-input"condition.This can be challenging when the source impedance is mismatched and produce nonzero forward signals(Vf)that significantly affect the measurement accuracy.To address this limitation,we developed a modified version of the"field decay method"based on the cavity differential equation.The proposed approach enables the precise calibration of f0.5 even under mismatch conditions.We tested the proposed approach on the SRF cavities of the Chinese Accelerator-Driven System Front-End Demo Superconducting Linac and compared the results with those obtained from a network analyzer.The two sets of results were consistent,indicating the usefulness of the proposed approach. 展开更多
关键词 Loaded quality factor Field decay method Superconducting cavity Mismatch Calibration Cavity differential equation Measurement Accelerator-driven system
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Investigation of the shock compression behaviors of Al/PTFE composites with experimental and a 3D mesoscale-model 认领 引用 被引量：6
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作者 Xiang-li Yang Yong He +2 位作者 Yuan He Chuan-ting Wang Jie Zhou 《Defence Technology（防务技术）》 SCIE EI CAS CSCD 2022年第1期62-71,共10页
The responses of Al/PTIFE reactive materials(RMs)under shock compression were investigated by a single-stage gas gun.A 3D mesoscale-model was established based on micro-computed tomography(micro-CT)slice images and co... The responses of Al/PTIFE reactive materials(RMs)under shock compression were investigated by a single-stage gas gun.A 3D mesoscale-model was established based on micro-computed tomography(micro-CT)slice images and confirmed with experimental results.In the high-pressure stage,the com-posites reacted partially,whereas there were no deviations between the partially reacted Hugoniot and the inert simulation results.The simulation reveals that the Teflon matrix melting on the high shock pressure.Melts and decomposition of the PTFE accelerated the diffusion of the atoms.Thus,the reactions of the Al/PTFE composites are more like a combustion rather than a detonation. 展开更多
关键词 AI/PTFE reactive materials 3D mesoscale-model Shock-assisted reaction Shock Hugoniot
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New thermal optimization scheme of power module in solid-state amplifier 认领 引用 被引量：4
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作者 Lie-Peng Sun Zhen-Yu Yuan +5 位作者 Cheng Zhang Xian-Bo Xu Jun-Gang Miao Jian-Hua Zhang Long-Bo Shi Yuan He 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2019年第4期143-149,共7页
The new 1 kW power module for ADS project needs the optimization of cooling design including water flow and tunnel layout, and the water flow of three tons per hour was chosen to be a goal for a 20 kW power source.Acc... The new 1 kW power module for ADS project needs the optimization of cooling design including water flow and tunnel layout, and the water flow of three tons per hour was chosen to be a goal for a 20 kW power source.According to analysis from the insertion and integrated loss, about 24 modules were integrated into the rated power. Thus, every module has a cooling flow of 2.1 L/min for RF heat load and power supply loss, which is very hard to achieve if no special consideration and techniques. A new thermal simulation method was introduced for thermal analysis of cooling plate through CST multi-physics suite,especially for temperature of power LDMOS transistor.Some specific measures carried out for the higher heat transfer were also presented in this paper. 展开更多
关键词 RF system Solid-state amplifier Power module Heat transfer coefficient
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Petrological and geochemical characteristics of mafic rocks from the Neoproterozoic Sugetbrak Formation in the northwestern Tarim Block,China 认领 引用 被引量：4
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作者 Hong-zhe Xie Xiang-kun Zhu +2 位作者 Xun Wang Yuan He Wei-bing Shen 《China Geology》 CAS CSCD 2023年第1期85-99,共15页
The Neoproterozoic Sugetbrak Formation in the Aksu area,which is located at the northwest margin of Tarim Block,comprises mafic rocks and provides key records of the evolution of the Rodinia supercontinent.However,the... The Neoproterozoic Sugetbrak Formation in the Aksu area,which is located at the northwest margin of Tarim Block,comprises mafic rocks and provides key records of the evolution of the Rodinia supercontinent.However,the genetic relationship among these mafic rocks exposed in different geographical sections are still unclear.In this study,the petrology,geochemistry,and Sr-Nd-Pb isotope geochemistry of the mafic rocks exposed in the Aksu-Wushi and Yuermeinark areas have been studied in some detail along three sections.The authors found that the mafic rocks in these three typical sections were mainly composed of pyroxene and plagioclase,containing a small amount of Fe-Ti oxides and with typical diabasic textures.All the mafic rocks in this region also showed similar geochemical compositions.They were characterised by high TiO2contents(1.47%–3.59%)and low MgO(3.52%–7.88%),K2O(0.12%–1.21%).Large ionic lithophile elements(LILEs)(Rb,Sr,and Cs)were significantly depleted.Meanwhile,high field strength elements(HFSEs)were relatively enriched.In the samples,light rare earth elements(LREEs)were enriched,while heavy rare earth elements(HREEs)were depleted.Based on the Zr/Nb,Nb/Y,and Zr/TiO2ratios,the Aksu mafic rocks belong to a series of sub-alkaline and alkaline transitional rocks.The mafic rocks along the three typical sections showed similar initial values of87Sr/86Sr(ISr)(0.7052–0.7097)and εNd(t)(–0.70 to–5.35),while the Pb isotopic compositions with206Pb/204Pb,207Pb/204Pb and208Pb/204Pb values of 16.908–17.982,15.487–15.721,37.276–38.603,respectively.Most of the samples plot into the area near EM-Ⅰ,indicating that the magma of the mafic rocks might have derived from a relatively enriched mantle with some crustal materials involved.The geochemical element characteristics of most samples showed typical OIB-type geochemical characteristics indicating that the source region had received metasomatism of recycled materials.Combining with the regional geological background and geochemical data,we inferred that the mafic rocks of the Sugetbrak Formation in the Aksu area were formed in an intraplate rift environment.Summarily,based on our study,the mafic rocks of the Sugetbrak Formation in the Aksu area were derived from a common enriched mantle source,and they were product of a magmatic event during the rift development period caused by the breakup of the Rodinia supercontinent. 展开更多
关键词 Mafic rocks Sugetbrak Formation Rodinia supercotinent Neoproterozoic Sr-Nd-Pb isotopes Mantle plume Geological survey engineering Tarim Block Xinjiang
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Role of the NLRP3 inflammasome in neurodegenerative diseases and therapeutic implications 认领 引用 被引量：11
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作者 Yanhui Duan Nathan Kelley Yuan He 《Neural Regeneration Research》 SCIE CAS CSCD 2020年第7期1249-1250,共2页
Neurodegenerative diseases are a group of neuronal disorders caused by progressive neuronal cell death in different regions of the human brain.Alzheimer's disease(AD)and Parkinson's disease(PD)are the most com... Neurodegenerative diseases are a group of neuronal disorders caused by progressive neuronal cell death in different regions of the human brain.Alzheimer's disease(AD)and Parkinson's disease(PD)are the most common types of neurodegenerative diseases that affect millions of people worldwide.There is no cure available for either disease.One of the pathological hallmarks of neurodegenerative diseases is the abnormal protein aggregation in the central nervous system. 展开更多
关键词 NLRP3 diseases degenerative
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Spatial-temporal Heterogeneity of Industrial Structure Transformation and Carbon Emission Effects in Xuzhou Metropolitan Area 认领 引用 被引量：3
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作者 QIU Fangdao YUAN He +1 位作者 BAI Liangyu LI Fei 《Chinese Geographical Science》 SCIE CSCD 2017年第6期904-917,共14页
Employing decoupling index and industrial structure characteristic bias index methods, this study analyzed the spatial-temporal characteristics of industrial structure transformations and their resulting carbon emissi... Employing decoupling index and industrial structure characteristic bias index methods, this study analyzed the spatial-temporal characteristics of industrial structure transformations and their resulting carbon emissions in the Xuzhou Metropolitan Area from 2000 to 2014, with a focus on their relationships and driving factors. Our research indicates that carbon emission intensity from industrial structures in the Xuzhou Metropolitan Area at first showed an increasing trend, which then decreased. Furthermore, the relationship between emissions and industrial economic growth has been trending toward absolute decoupling. From the perspective of the center-periphery, the Xuzhou Metropolitan Area formed a concentric pattern, where both progress towards low emissions and the level of technological advancement gradually diminished from the center to the periphery. In terms of variation across provinces, the ISCB index in the eastern Henan has decreased the slowest, followed by the southern Shandong and the northern Anhui, with the northern Jiangsu ranking last. During this period, resource-and labor-intensive industries were the primary growth industries in the northern Anhui and the eastern Henan, while labor-intensive industries dominated the southern Shandong and capital-intensive industries dominated the northern Jiangsu. In terms of city types, the spatial pattern for industrial structure indicates that recession resource-based cities had higher carbon emission intensities than mature resource-based cities, followed by non-resource-based cities and regenerative resource-based cities. Generally, the industrial structure in the Xuzhou Metropolitan Area has transformed from being resource-intensive to capital-intensive, and has been trending toward technology-intensive as resource availability has been exploited to exhaustion and then been regenerated. Industrial structure has been the leading factor causing heterogeneity of carbon emission intensities between metropolitan cities. Therefore, the key to optimizing the industrial structure and layout of metropolitan areas is to promote industrial structure transformation and improve the system controlling collaborative industrial development between cities. 展开更多
关键词 industrial structure transformation industrial structure characteristic bias carbon emission effect spatial-temporal pattern Xuzhou Metropolitan Area
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Morin,a matrix metalloproteinase 9 inhibitor,attenuates endothelial-to-mesenchymal transition in atherosclerosis by downregulating Notch-1 signaling 认领 引用 被引量：3
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作者 Yuan He Xiao-xuan Qin +1 位作者 Ming-wei Liu Wei Sun 《Journal of Integrative Medicine》 SCIE CAS CSCD 2024年第6期683-695,共13页
Objective:Atherosclerotic cardiovascular disease poses a significant health challenge globally.Recent findings highlight the pivotal role of the endothelial-to-mesenchymal transition(End MT)in atherosclerosis.Morin is... Objective:Atherosclerotic cardiovascular disease poses a significant health challenge globally.Recent findings highlight the pivotal role of the endothelial-to-mesenchymal transition(End MT)in atherosclerosis.Morin is a bioflavonoid mainly extracted from white mulberry,a traditional Chinese herbal medicine with anti-inflammatory and antioxidant properties.This study examines whether morin can alleviate atherosclerosis by suppressing End MT and seeks to elucidate the underlying mechanism.Methods:We induced an in vitro End MT model in human umbilical vein endothelial cells(HUVECs)by stimulating the cells with transforming growth factor-β1(TGF-β1)(10 ng/m L)for 48 h.The in vivo experiments were performed in an atherosclerosis model using apolipoprotein E(Apo E)-/-mice fed with a high-fat diet(HFD).Mice in the intervention group were given morin(50 mg/kg)orally for 4 weeks.Molecular docking and microscale thermophoresis were assayed to understand the interactions between morin and matrix metalloproteinase-9(MMP-9).Results:Morin inhibited the expression of End MT markers in a dose-dependent manner in TGF-β1-treated HUVECs.Administering 50μmol/L morin suppressed the upregulation of MMP-9 and Notch-1 signaling in TGF-β1-induced End MT.Moreover,the overexpression of MMP-9 activated Notch-1 signaling,thereby reversing morin's inhibitory effect on End MT.In the HFD-induced atherosclerotic Apo E-/-mice,morin notably reduced aortic intimal hyperplasia and plaque formation by suppressing End MT.Furthermore,morin demonstrated a strong binding affinity for MMP-9.Conclusion:Morin acts as an MMP-9 inhibitor to disrupt End MT in atherosclerosis by limiting the activation of Notch-1 signaling.This study underscores morin's potential utility in the development of antiatherosclerotic medication. 展开更多
关键词 Morin Endothelial-to-mesenchymal transition Atherosclerosis Traditional Chinese medicine Matrix metalloproteinase-9
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Beam dynamics,RF measurement,and commissioning of a CW heavy ion IH-DTL 认领 引用 被引量：2
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作者 Heng Du You-Jin Yuan +10 位作者 Zhong-Shan Li Zhi-Jun Wang Peng Jin Xiao-Ni Li Guo-Zhu Cai Wen-Wen Ge Guo-Feng Qu Yuan He Jia-Wen Xia Jian-Cheng Yang Xue-Jun Yin 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2018年第3期143-155,共13页
A 53.667 MHz CW(continuous-wave) heavy ion IH-DTL has been designed for the SSC-LINAC injector of HIRFL-CSR(Heavy Ions Research Facility at Lanzhou-Cooling Storage Ring). It accelerates ions with maximum mass-to-charg... A 53.667 MHz CW(continuous-wave) heavy ion IH-DTL has been designed for the SSC-LINAC injector of HIRFL-CSR(Heavy Ions Research Facility at Lanzhou-Cooling Storage Ring). It accelerates ions with maximum mass-to-charge ratio of 7.0 from 143 to 295 ke V/u. Low-power RF measurement of the IH-DTL1 has been taken to investigate the RF performance and the quality of the electric field distribution on the beam axis.The measured Q_0 value and the shunt impedance are 10,400 and 198 MX/m, respectively. The electric field distributions on and around the beam axis were evaluated and compared with the design value. By a new approach,the dipole field component is also estimated. The beam dynamics simulation using measured field distribution was presented in this paper. Based on the dynamics analysis in both transverse and longitudinal phase space, the field distribution can meet the design requirement. Finally, the RF conditioning and very first beam commissioning on the IH-DTL1 were finished. The beam test results agree well with the simulation results; what's more, the property of the variable output beam energy about the separated functions DTL was verified. 展开更多
关键词 Linac RF measurement Beam dynamic simulation Commissioning
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Investigation of factors affecting vertical sag of stretched wire 认领 引用 被引量：2
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作者 Jian-Dong Yuan Jun-Xia Wu +7 位作者 Bin Zhang Yuan He Jun-Hui Zhang Wen-Jun Chen Shao-Ming Wang Guo-Zhen Sun Xu-Dong Zhang Li-Song Yan 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2021年第2期90-100,共11页
To study vertical sag requirements and factors affecting the stretched wire alignment method,the vertical sag equation is first derived theoretically.Subsequently,the influencing factors(such as the hanging weight or ... To study vertical sag requirements and factors affecting the stretched wire alignment method,the vertical sag equation is first derived theoretically.Subsequently,the influencing factors(such as the hanging weight or tension,span length,temperature change,elastic deformation,and the Earth’s rotation)of the vertical sag are summarized,and their validity is verified through actual measurements.Finally,the essential factors affecting vertical sag,i.e.,the specific strength and length,are discussed.It is believed that the vertical sag of a stretched wire is proportional to the square of the length and inversely proportional to the specific strength of the material. 展开更多
关键词 Stretched wire Alignment Vertical sag Catenary Hyperbolic cosine Linear density Earth rotation
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