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虚拟现实(VR)技术在感染科实践教学中的应用 认领 引用
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作者 夏国美 刘月英 +2 位作者 袁吉 杨雅茹 张振华 《安徽医专学报》 2026年第3期82-85,共4页
目的:探讨虚拟现实(VR)技术在感染科实践教学中的应用效果。方法:选取在某医院参加感染科实践教学的医学研究生和规培医生160名,采用随机数表法分为对照组和实验组,各80名。对照组采用传统教学,实验组在相同教学周期和总课时内嵌入VR情... 目的:探讨虚拟现实(VR)技术在感染科实践教学中的应用效果。方法:选取在某医院参加感染科实践教学的医学研究生和规培医生160名,采用随机数表法分为对照组和实验组,各80名。对照组采用传统教学,实验组在相同教学周期和总课时内嵌入VR情景化强化训练。比较两组理论考试成绩、操作技能、临床决策能力及教学满意度。结果:教学后,实验组学员理论成绩高于对照组(P<0.001):实验组学员各项操作技能考核成绩、各维度临床决策能力评分及教学总满意度均高于对照组(P<0.05)。结论:感染科实践教学中应用VR技术可在一定程度上提高学员的理论成绩、操作技能、临床决策能力和教学满意度,是传统教学的有益补充。 展开更多
关键词 虚拟现实 感染科 实践教学 医学研究生 规培医生
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Pt nanocluster-catalyzed hydrogen evolution reaction:Recent advances and future outlook 认领 引用 被引量:3
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作者 Hongliang Zeng Yuan Ji +4 位作者 Jinfeng Wen Xu Li Tingting Zheng Qiu Jiang Chuan Xia 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第3期52-69,共18页
As hydrogen energy technologies gain momentum,the role of renewable energy in facilitating sustainable hydrogen production is becoming increasingly critical.As a hydrogen production method,water electrolysis has attra... As hydrogen energy technologies gain momentum,the role of renewable energy in facilitating sustainable hydrogen production is becoming increasingly critical.As a hydrogen production method,water electrolysis has attracted much attention from researchers due to its operational simplicity,the high purity of the hydrogen generated,and its potential for achieving zero carbon emissions throughout the process.Numerous studies has been manipulated on platinum(Pt)-based catalysts,which exhibit superior performance in hydrogen evolution reactions.Within this category,Pt nanoclusters stand out due to their unique attributes,such as quantum size effects and unique coordination environments.These features enable them to outperform both Pt metal atoms and nanoparticles in hydrogen evolution reactions regarding activity and stability.Here,we primarily delve into the reaction mechanisms underlying Pt nanocluster-based hydrogen catalysts,with particular emphasis on the interactions between the metal catalysts and their associated support materials.We provide an exhaustive summary of the strategies employed in the synthesis,the structural analyses conducted,and the performance metrics observed for Pt nanocluster catalysts when paired with various supporting materials.In closing,we explore the future potential and challenges facing Pt nanocluster-based catalysts in the context of industrial water electrolysis,along with emerging avenues for their design and optimization. 展开更多
关键词 Platinum Nanoclusters Electronic interaction Hydrogen evolution Active sites
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Advances in platinum-based materials for electrocatalytic ammonia oxidation:Mechanisms and research progress 认领 引用 被引量:1
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作者 Youpeng Wang Yuan Ji +5 位作者 Chengbo Li Zhaoyang Chen Xu Li Tingting Zheng Qiu Jiang Chuan Xia 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第9期269-279,共11页
As an emergent energy carrier,ammonia benefits from a well-established industrial infrastructure for its transportation and production,positioning it as a promising candidate toward a carbon-free energy landscape.With... As an emergent energy carrier,ammonia benefits from a well-established industrial infrastructure for its transportation and production,positioning it as a promising candidate toward a carbon-free energy landscape.Within this context,the electrocatalytic ammonia oxidation reaction(AOR)is pivotal.Platinum(Pt),recognized as the most efficient AOR catalyst,has undergone extensive development over the years,yielding notable advancements across various domains,ranging from elucidating the reaction mechanism to exploring innovative materials.This review begins by elucidating the mechanism of ammonia oxidation,summarizing the evolution of the mechanism and the diverse intermediates identified through various detection methods.Subsequently,it outlines the research progress surrounding different Pt-based catalysts,followed by a discussion on standard protocols for electrochemical ammonia oxidation testing,which facilitates meaningful comparisons across studies and catalyzes the development of more efficient and potent catalysts.Moreover,the review addresses current challenges in ammonia oxidation and outlines potential future directions,providing a comprehensive outlook on the field. 展开更多
关键词 Ammonia energy Electrochemical ammonia oxidation reaction intermediate detection Pt-based catalyst Electrochemical protocols
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Commercialization of electrochemical CO2 reduction:HCOOH pathway versus CO pathway 认领 引用
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作者 Zhaoyang Chen Qingtian Zhong +6 位作者 Qiqige Wulan Yuan Ji Chunxiao Liu Xu Li Tingting Zheng Qiu Jiang Chuan Xia 《Chinese Journal of Catalysis》 SCIE EI CAS CSCD 2025年第2期52-57,共6页
The objective of electrochemical CO2 reduction technologies(ECRs)is notably audacious:to revolutionize the market by generating fuel and essential chemicals at a more competitive price than petrochemicals can offer... The objective of electrochemical CO2 reduction technologies(ECRs)is notably audacious:to revolutionize the market by generating fuel and essential chemicals at a more competitive price than petrochemicals can offer,all while prioritizing environmental sustainability.To expedite the commercialization of ECR technology,we discuss here how ECR can reshape the industry landscape through 2e−pathways. 展开更多
关键词 Carbondioxideconversion Electrochemical reduction 2e pathways Industry landscape
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Axial coordination engineering of cobalt phthalocyanine enables efficient CO2electrolysis to CO 认领 引用
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作者 Yawei Hong Chunxiao Liu +11 位作者 Chengbo Li Haoyuan Wang Yuan Ji Xinyan Zhang Yujing Ren Zhaoyang Chen Qisheng Zeng Qiu Jiang Tingting Zheng Kun Jiang Xu Li Chuan Xia 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2025年第8期252-259,共8页
Electrocatalytic CO2-to-CO conversion is crucial for advancing sustainable processes,and providing essential feedstocks for the chemical industry.Cobalt phthalocyanine(CoPc)is a well-established molecular catalyst ... Electrocatalytic CO2-to-CO conversion is crucial for advancing sustainable processes,and providing essential feedstocks for the chemical industry.Cobalt phthalocyanine(CoPc)is a well-established molecular catalyst for this conversion;however,maintaining high selectivity at industrially relevant current densities remains a significant challenge.Herein,we present a Co–N5local structure anchored on nitrogen-doped carbon nanotubes through axial nitrogen coordination engineering to CoPc(CoPc/N-CNTs).The catalyst demonstrates near-unity CO selectivity and a high CO turnover frequency,peaking at 19.2 s−1across a wide range of overpotentials.In flow cell tests,CoPc/N-CNTs achieve a CO Faradaic efficiency exceeding 95%at a current density of−800 mA cm−2.When integrated into a membrane electrode assembly,it maintained over 90%CO Faradaic efficiency at an industrial-scale current of−5 A for up to 20 h.Mechanistic studies revealed that Co–N5active sites accelerate*COOH formation and inhibit deeper*CO reduction to CH3OH while reducing HER activity by lowering H2O surface coverage.These findings offer a delicate catalyst design that enables the efficient and sustained conversion of CO2to CO. 展开更多
关键词 Molecular catalysts Axial coordination Electrochemical CO2reduction Cobalt phthalocyanine
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Guideline of precisional testing in intrahepatic cholangiocarcinoma:an international expert consensus 认领 引用
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作者 Xin Zhang Jing Han +13 位作者 Ruoyu Shi Bing Yu Xuchen Zhang Bin Li Xia Sheng Zengshan Li Yining Zou Huichuan Sun Guoming Shi Hanlin LWang Jian Zhou Jia Fan Wenming Cong Yuan Ji 《Clinical Cancer Bulletin》 2025年第1期80-93,共14页
Intrahepatic cholangiocarcinoma(ICC)is a highly heterogeneous tumor.Molecular profiling serves as the foundation for personalized treatment of ICC.Comprehensive molecular testing is needed to identify more patients th... Intrahepatic cholangiocarcinoma(ICC)is a highly heterogeneous tumor.Molecular profiling serves as the foundation for personalized treatment of ICC.Comprehensive molecular testing is needed to identify more patients that are suitable for specific targeted therapies.This consensus is based on clinical data from both domestic and international sources,tailored to the Chinese context,and focuses on key targets for ICC.We present 15 recommendations aimed at guiding the precision detection of ICC. 展开更多
关键词 Intrahepatic cholangiocarcinoma Precision detection Biomarkers Personalized treatment
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电化学氧化技术在水处理中的研究进展 认领 引用
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作者 袁吉 王蒙 《辽宁化工》 CAS 2026年第3期507-511,共5页
电化学氧化技术作为一种高效的高级氧化方法,在处理难降解有机物污染方面展现出巨大潜力。该技术通过直接氧化和间接氧化2种途径降解污染物,其中间接氧化利用阳极产生的强氧化性中间介质(如羟基自由基·OH、活性氯等)实现污染物高... 电化学氧化技术作为一种高效的高级氧化方法,在处理难降解有机物污染方面展现出巨大潜力。该技术通过直接氧化和间接氧化2种途径降解污染物,其中间接氧化利用阳极产生的强氧化性中间介质(如羟基自由基·OH、活性氯等)实现污染物高效去除。本文综述了电化学氧化技术在饮用水厂除藻、腐殖酸去除及细菌杀灭等方面的应用效果,特别是掺硼金刚石(BDD)阳极在这些应用中的优异表现。探讨了新型电极材料(如BDD电极)、三维电极结构、脉冲式供电方式以及与其他水处理技术联用的最新进展。 展开更多
关键词 电化学 羟基自由基 水处理 研究进展
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高质量发展视域下三级甲等肿瘤专科医院的发展情况——基于2020—2023年13家医院的数据分析 认领 引用
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作者 袁吉 钱稳吉 +1 位作者 陈钰 姜艳 《中国肿瘤》 CAS CSCD 北大核心 2025年第7期546-551,共6页
[目的]分析我国三级甲等肿瘤专科医院高质量发展工作取得的成效及面临的挑战。[方法]采用便利抽样方法,选择13家三级甲等肿瘤专科医院,收集2020—2023年共4个维度、8项指标数据,其中门诊量、住院量、手术量反映服务能级;平均住院日反映... [目的]分析我国三级甲等肿瘤专科医院高质量发展工作取得的成效及面临的挑战。[方法]采用便利抽样方法,选择13家三级甲等肿瘤专科医院,收集2020—2023年共4个维度、8项指标数据,其中门诊量、住院量、手术量反映服务能级;平均住院日反映服务效率;开放床位数反映物质要素;职工数、医护比、高级职称人员占比反映人才要素。采用广义估计方程对推动公立医院高质量发展相关政策实施前后数据进行对比分析。[结果]相比较于2020年,2023年13家三级甲等肿瘤专科医院平均门诊量增长55.47%、住院量增长50.25%、手术量增长46.17%,平均住院日缩短18.98%,开放床位数增长10.02%,职工数增长13.03%,差异均具有统计学意义(P均0.05)。[结论]2020—2023年三级甲等肿瘤专科医院总体的服务能级和服务效率均稳步提升,资源配置逐渐从物质要素向人才要素倾斜,投入少、产出高,高质量发展初见成效。未来需重点优化人员结构,增加护士配备,加强对高层次人才的培养。 展开更多
关键词 肿瘤专科医院 三级甲等医院 高质量发展 卫生政策 广义估计方程
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合并右上肺B2下移变异的胸腔镜右下肺癌根治术1例及解剖学分析 认领 引用
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作者 鲍峰 毛宁 +1 位作者 元及 孙登群 《中国临床解剖学杂志》 CSCD 北大核心 2025年第6期741-744,共4页
电视辅助胸腔镜手术(video assisted thoracoscopic surgery,VATS)现已成为非小细胞肺癌(non-small cell lung cancer,NSCLC)外科治疗的首选术式。而在术前利用支气管、血管CT三维重建(three dimensional computed tomography bronchogr... 电视辅助胸腔镜手术(video assisted thoracoscopic surgery,VATS)现已成为非小细胞肺癌(non-small cell lung cancer,NSCLC)外科治疗的首选术式。而在术前利用支气管、血管CT三维重建(three dimensional computed tomography bronchography and angiography,3D-CTBA)技术精准识别气管支气管及肺血管的解剖变异,对优化手术规划、降低并发症风险至关重要。近期我们完成1例胸腔镜右下肺癌根治术,由于术前准确识别了右上肺B2下移及肺血管异常,术中规避了变异可能带来的安全隐患,取得了良好的治疗效果。现通过该病例结合文献复习右上肺B2下移这一罕见解剖异常。 展开更多
关键词 三维重建 胸腔镜手术 非小细胞肺癌
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Epithelioid angiomyolipoma of the liver:Cross-sectional imaging findings of 10 immunohistochemically-verified cases 认领 引用 被引量:31
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作者 Peng-Ju Xu Yan Shan +3 位作者 Fu-Hua Yan Yuan Ji Ying Ding Mei-Lin Zhou 《World Journal of Gastroenterology》 SCIE CAS 2009年第36期4576-4581,共6页
AIM: To retrospectively evaluate the computed tomography (CT)/magnetic resonance imaging (MRI) imaging features of epithelioid angiomyolipoma of the liver (Epi-HAML), with pathology as a reference. METHODS: Th... AIM: To retrospectively evaluate the computed tomography (CT)/magnetic resonance imaging (MRI) imaging features of epithelioid angiomyolipoma of the liver (Epi-HAML), with pathology as a reference. METHODS: The CT/MRI findings (number, diameter, lobar location, and appearance of lesions) in a series of 10 patients with 12 pathologically proven epithelioid angiomyolipomas of the liver were retrospectively analyzed. The imaging features, including attenuation/ signal intensity characteristics, presence of fat, hypervascular, outer rim, and vessels within lesion, were evaluated and compared with that of non-Epi- HAML in 11 patients (13 lesions). The Fisher exact test was used to compare difference in probability of imaging features between the two types. RESULTS: For 21 patients, CT images of 15 patients and MR images of six patients were available. No patient underwent two examinations. For the 15 patients with a CT scan, all HAML lesions in the two groups (10 Epi-HAML and seven non-Epi-HAML) manifested as hypoattenuation. For the six patients with MRI, all lesions (two Epi-HAML and six non-Epi- HAML) were hypointense on TlWI (fat suppression) and hyperintense on T2WI. There were 10 non-Epi-HAML, but only two Epi-HAML lesions showed the presence of fat, which significantly different between the two types (P = 0.005). On the dynamic contrast enhancement (DCE) imaging, eight Epi-HAML, and 13 non-Epi lesions manifested as hypervascular. Punctate or curved vessels were displayed in 10 Epi-HAML as well as in nine non- Epi lesions and outer rim enhancement could be found with eight Epi-HAML as well as six non-Epi lesions. CONCLUSION: Little or no presence of adipose tissue was found to be an imaging feature of Epi- HAML, compared with the non-Epi type. In addition, hypervascularity with opacification of central punctiform or filiform vessels on DCE would be a characteristic enhancement pattern for Epi-HAML. 展开更多
关键词 Epithelioid angiomyolipoma Liver Immunohistochemical staining Magnetic resonance imaging Computed X-ray tomography
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Applications of Metal–Organic Frameworks and Their Derivatives in Electrochemical CO2Reduction 认领 引用 被引量:16
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作者 Chengbo Li Yuan Ji +8 位作者 Youpeng Wang Chunxiao Liu Zhaoyang Chen Jialin Tang Yawei Hong Xu Li Tingting Zheng Qiu Jiang Chuan Xia 《Nano-Micro Letters》 SCIE EI CAS CSCD 2023年第8期72-115,共44页
Electrochemically reducing CO2to more reduced chemical species is a promising way that not only enables the conversion of intermittent energy resources to stable fuels,but also helps to build a closed-loop anthropo... Electrochemically reducing CO2to more reduced chemical species is a promising way that not only enables the conversion of intermittent energy resources to stable fuels,but also helps to build a closed-loop anthropogenic carbon cycle.Among various electrocatalysts for electrochemical CO2reduction,multifunctional metal–organic frameworks(MOFs)have been employed as highly efficient and selective heterogeneous electrocatalysts due to their ultrahigh porosity and topologically diverse structures.Up to now,great progress has been achieved in the design and synthesis of highly active and selective MOF-related catalysts for electrochemical CO2reduction reaction(CO2RR),and their corresponding reaction mechanisms have been thoroughly studied.In this review,we summarize the recent progress of applying MOFs and their derivatives in CO2RR,with a focus on the design strategies for electrocatalysts and electrolyzers.We first discussed the reaction mechanisms for different CO2RR products and introduced the commonly applied electrolyzer configurations in the current CO2RR system.Then,an overview of several categories of products(CO,HCOOH,CH4,CH3OH,and multi-carbon chemicals)generated from MOFs or their derivatives via CO2RR was discussed.Finally,we offer some insights and perspectives for the future development of MOFs and their derivatives in electrochemical CO2reduction.We aim to provide new insights into this field and further guide future research for large-scale applications. 展开更多
关键词 Metal-organic frameworks Derivatives Catalyst CO2reduction reaction Electrocatalysis
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Role of MR in the differentiation of IgG4-related from non-IgG4-related hepatic inflammatory pseudotumor 认领 引用 被引量:9
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作者 Ruo-Fan Sheng Chang-Wen Zhai +3 位作者 Yuan Ji Cai-Zhong Chen Li Yang Meng-Su Zeng 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2017年第6期631-637,共7页
BACKGROUND:Hepatic inflammatory pseudotumor(IPT)is classified into 2 types based on IgG 4 stain:IgG 4-related and non-IgG4-related; the two types differ not only in their pathological characteristics, but also in the ... BACKGROUND:Hepatic inflammatory pseudotumor(IPT)is classified into 2 types based on IgG 4 stain:IgG 4-related and non-IgG4-related; the two types differ not only in their pathological characteristics, but also in the clinical features. This study aimed to investigate the MR character of hepatic IPT,and differentiate the IgG4-related IPT from the non-IgG4-related IPT.METHODS:Twenty-five patients with 27 histologically proven hepatic IPTs were retrospectively analyzed. Ten lesions were diagnosed as IgG4-related IPT, and the other 17 as non-IgG4-related IPT. The MR signal features on T1,T2-weighted, dynamic-enhanced, and diffusion-weighted imaging were evaluated and compared. RESULTS:The dominant lesions were subcapsularly distributed(n=17, 63.0%) with clear boundary(n=20, 74.1%), and showed progressive enhancement pattern(n=21, 77.8%) with diffuse homogeneous(n=12, 44.4%) or heterogeneous(n=8,29.6%) hyperintensity, accompanied by delayed capsule-like enhancement(n=17, 63.0%) and central nonenhanced areas(n=18, 66.7%). Morphological features(P>0.05) were not sufficient to differentiate IgG4-related IPT from non-IgG4-related IPT; the wash-out pattern was only found in 2 IgG 4-related IPT, while the progressive enhancement pattern was more common in the non-IgG4-related lesions(n=16)(P=0.022).During portal and delayed phases, iso-/hypoenhanced lesions were only seen in 3 IgG4-related IPT, and circular-enhanced lesions(n=5) existed exceptionally in the non-IgG4-related group with significant differences(P=0.029 and 0.027). Most IgG4-related IPTs had lower apparent diffusion coefficient compared with the liver parenchyma(n=6), while most non-IgG4-related IPTs had higher apparent diffusion coefficient value(n=13)(P=0.046).CONCLUSIONS:Although MR images of hepatic IPT have certain characteristics, they are not enough to differentiate IgG4-related IPT from non-IgG4-related IPT. The enhancement pattern, signal features on portal and delayed phases, and the apparent diffusion coefficient value of the lesion may be helpful for the diagnosis. 展开更多
关键词 liver inflammatory pseudotumor IgG4 magnetic resonance imaging
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A series of 64 cases of pancreatic cystic neoplasia from an institutional study of China 认领 引用 被引量:3
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作者 Yuan Ji Wen-Hui Lou +6 位作者 Da-Yong Jin Tian-Tao Kuang Meng-Su Zeng Yun-Shan Tan Hai-Ying Zeng Akesu Sujie Xiong-Zeng Zhu 《World Journal of Gastroenterology》 SCIE CAS 2006年第45期7380-7387,共8页
AIM: To recognize cystic neoplasia of the pancreas and thus to identify a panel of curable diseases. METHODS: Sixty-four cases of cystic neoplasia of the pancreas, including 28 cases of intraductal papillary mucinous ... AIM: To recognize cystic neoplasia of the pancreas and thus to identify a panel of curable diseases. METHODS: Sixty-four cases of cystic neoplasia of the pancreas, including 28 cases of intraductal papillary mucinous neoplasia (IPMN), 12 cases of serous cystic neoplasia (SCN), 11 cases of mucinous cystic neoplasia (MCN), 11 cases of solid pseudo-papillary neoplasia (SPN), and 2 cases of solid tumor with cystic degeneration were examined immunohistochemically for their expression of MUC1, MUC2, MUC4, MUC5AC, and MUC6, as well as other related antigens. RESULTS: Adenoma type of IPMN and borderline lesions exhibited high expressions of MUC2, and MUC5AC. In contrast, IPMN with invasive carcinoma component showed MUC1 immunoreactivity. SCN was mainly positive for MUC1 and MUC6, while negative for MUC2, MUC4 and MUC5AC. Noninvasive MCN, regardless of its cellular atypia degree, was positive for MUC5AC and negative for MUC1. MUC1 expression was only observed in patients with an invasive component. No mucin expression was found in SPN. CONCLUSION: Mucin profile may, in conjunction with histologic study, provide important information on tumor types and patient treatment of cystic neoplasia of the pancreas. 展开更多
关键词 Pancreas Cystic neoplasm Mucin Differential diagnosis Diagnosis
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Hepatocellular carcinoma with concomitant hepatic angiomyolipoma and cavernous hemangioma in one patient 认领 引用 被引量:3
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作者 Xiao-Wen Ge Hai-Ying Zeng +5 位作者 Akesu Su-Jie Min Du Yuan Ji Yun-Shan Tan Ying-Yong Hou Jian-Fang Xu 《World Journal of Gastroenterology》 SCIE CAS 2015年第11期3414-3419,共6页
The risk of developing hepatocellular carcinoma(HCC) is strongly associated with hepatitis B virus infection.Hepatic angiomyolipoma(AML),a rare benign tumor,is composed of a heterogeneous mixture of adipose cells,smoo... The risk of developing hepatocellular carcinoma(HCC) is strongly associated with hepatitis B virus infection.Hepatic angiomyolipoma(AML),a rare benign tumor,is composed of a heterogeneous mixture of adipose cells,smooth muscle cells and blood vessels.Here,we report the case of a 44-year-old man who developed HCC with a concomitant hepatic AML and a cavernous hemangioma,in the absence of cirrhosis.To our knowledge,based on an extensive literature search using the www.pubmed.gov website,this is the first report of an HCC case with both concomitant AML and cavernous hemangioma at the same position in the liver.The presence of the hepatitis B surface antigen was detected,but the liver function was normal.Clinical and pathological data were collected before and during the treatment.Hepatic AML was diagnosed based on the typical histological characteristics and immunohistochemical staining,which revealed,a positive staining with a melanocytic cell-specific monoclonal antibody.There was no evidence of tuberous sclerosis complex in this patient.Although the HCC was poor- to moderately-differentiated,the characteristics of the AML and the cavernous hemangioma in this patient did not match any criteria for malignancy.Hepatectomy followed by transarterial chemoembolization treatment were effective therapeutic methods for the adjacent lesions in this patient.This case is an interesting coincidence. 展开更多
关键词 Angiomyolipoma Hepatocellular carcinoma Cavernous
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Therapy-Related Acute Myeloid Leukemia in A Primary Pulmonary Leiomyosarcoma Patient with Skin Metastasis 认领 引用 被引量:2
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作者 Yan Ma Bo-bin Chen +4 位作者 Xiao-ping Xu Guo-wei Lin Yuan Ji Sujie Akesu Haiying Zen 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2011年第3期236-238,共3页
Primary pulmonary leiomyosarcoma (LMS) is a very unusual tumor.Although LMS has well-known metastatic potential,cutaneous metastasis is a remarkably uncommon.Exposure to cytotoxic agents could lead to "therapy-rela... Primary pulmonary leiomyosarcoma (LMS) is a very unusual tumor.Although LMS has well-known metastatic potential,cutaneous metastasis is a remarkably uncommon.Exposure to cytotoxic agents could lead to "therapy-related myeloid neoplasm" (t-MN).Starting from 2008,the World Health Organization (WHO) has adopted the term to cover the spectrum of malignant diseases previously known as therapy-related acute myeloid leukemia (t-AML),therapy-related myelodysplastic syndrome (t-MDS) and therapy-related myelodysplastic/myelo-proliferative neoplasm (t-MDS/MPN).We described the onset of t-MDS and progression to t-AML in one case diagnosed as primary pulmonary LMS with cutaneous metastasis.This patient achieved complete remission (CR) after three courses of IA regimen chemotherapy (idarubicin 5 mg/d,d 1-3;cytarabine 100 mg/d,d 1-5) and 1 course of HA chemotherapy regimen (homoharringtonine 3 mg/d,d 1-3;cytarabine 100 mg/d,d 1-7).This case presents the natural course of therapy-related neoplasm and provides therapeutic experience for t-AML. 展开更多
关键词 Therapy-related myelodysplastic syndrome Therapy-related acute myeloid leukemia Leiomyosarcoma Metastasis Skin
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Solitary fibrous tumor of the liver 认领 引用 被引量:3
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作者 Yuan Ji Jia Fan +3 位作者 Yang Xu Jian Zhou Hai-Ying Zeng Yun-Shan Tan 《Hepatobiliary & Pancreatic Diseases International》 CAS 2006年第1期151-153,共3页
BACKGROUND:Solitary fibrous tumor of the liver is a rare neoplasm.So far,23 cases have been described in the English literature.We reported an additional case.METHODS:A 46-year-old woman presented with abdominal mass ... BACKGROUND:Solitary fibrous tumor of the liver is a rare neoplasm.So far,23 cases have been described in the English literature.We reported an additional case.METHODS:A 46-year-old woman presented with abdominal mass for 2 weeks.Both abdominal sonography and CT scan showed a solid mass occupying the right lobe of the liver.Right lobectomy was performed and the tumor was resected.RESULTS:Pathological examination showed spindle cell and fibroblast-like cells within the collagenous troma.On immunohistochemical staining,these spindle tumor cells showed diffusely CD34 positive reactivity.The post-operative course was uneventful.The patient recovered smoothly,and was alive half a year without evidence of disease recurrence.CONCLUSIONS:The proper diagnosis was depended on CD34 immunohistochemical study.The number of solitary fibrous tumor of the liver reported to date is too limited to confirm the definite prognosis of the tumor. 展开更多
关键词 liver neoplasm solitary fibrous tumor CD34
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Understanding the Thermal Impedance of Silicone Rubber/Hexagonal Boron Nitride Composites as Thermal Interface Materials 认领 引用 被引量:2
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作者 Yuan Ji Shi-Da Han +3 位作者 Hong Wu Shao-Yun Guo Feng-Shun Zhang Jian-Hui Qiu 《Chinese Journal of Polymer Science》 SCIE EI CAS CSCD 2024年第3期352-363,I0008,共12页
Silicone rubber(SR) composites are most widely used as thermal interface materials(TIMs) for electronics heat dissipation. Thermal impedance as the main bottleneck limiting the performance of TIMs is usually neglected... Silicone rubber(SR) composites are most widely used as thermal interface materials(TIMs) for electronics heat dissipation. Thermal impedance as the main bottleneck limiting the performance of TIMs is usually neglected. Herein, the thermal impedance of SR composites loaded with different levels of hexagonal boron nitride(h-BN) as TIMs was elaborated for the first time by the ASTM D 5470 standard test and finite element analysis. It was found that elastic modulus and surface roughness of SR composites increased with the increase of h-BN content, indicating that the conformity was reduced. When the assembly pressure was 0.69 MPa, there existed an optimal h-BN content at which the contact resistance was minimum(0.39 K·cm2·W-1). Although the decreased bond line thickness(BLT) by increasing the assembly pressure was beneficial to reduce the thermal impedance, the proper assembly pressure should be selected to prevent the warpage of the contact surfaces and the increase in contact resistance, according to the compression properties of the SR composites. This study provides valuable insights into fabrication of high-performance TIMs for modern electronic device applications. 展开更多
关键词 Thermal interface materials Hexagonal boron nitride Thermal impedance Surfaces
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Lipid storage regulator CdsA is essential for Drosophila metamorphosis 认领 引用 被引量:1
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作者 Yuan Liu Yuan Ji +2 位作者 Xia Li Guanghou Shui Xun Huang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2019年第4期231-234,共4页
Steroid hormones are one of the major bioactive lipid species that regulate a large number of physiological processes including developmental transitions, growth, metabolism, inflammation, immune response and reproduc... Steroid hormones are one of the major bioactive lipid species that regulate a large number of physiological processes including developmental transitions, growth, metabolism, inflammation, immune response and reproduction in animals. In insects, steroid hormones ecdysone and 20-hydroxyecdysone (20E) trigger the major transitional events, molting and metamorphosis (Thummel, 1996). In Drosophila, ecdysone synthesis primarily occurs in the prothoracic gland, an endocrine gland expressing a large number of ecdysone biosynthetic enzymes required for a series of hydroxylation and oxidation steps. 展开更多
关键词 Drosophila metamorphosis major bioactive lipid species immune response
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滨海地区地面沉降对室外建筑工程的影响及防治措施研究 认领 引用 被引量:2
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作者 应永祥 李海仁 +6 位作者 蔡思聪 尹欢 胡忠志 袁骥 杨可悦 于凯圣 王睿欣 《建筑施工》 2025年第4期596-600,共5页
为减少地面沉降引发的地下管线断裂、区域沉陷、建筑开裂、变形等问题,以台州湾新区滨海疏浚填土区地面沉降为研究对象,分析地面沉降对建筑工程的影响效应,总结出当前工程中的“长尾效应”“高差效应”,并针对性地提出室外台阶防沉降结... 为减少地面沉降引发的地下管线断裂、区域沉陷、建筑开裂、变形等问题,以台州湾新区滨海疏浚填土区地面沉降为研究对象,分析地面沉降对建筑工程的影响效应,总结出当前工程中的“长尾效应”“高差效应”,并针对性地提出室外台阶防沉降结构、室外管线防沉降结构、路面防沉降、地下室外墙防跳车、散水防沉降等一系列防治措施,以降低室外建筑结构开裂、地下管道破损等风险,可为建筑工程施工提供参考。 展开更多
关键词 滨海地区 地面沉降 管线断裂 防治措施
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Administration of granulocyte colony stimulating factor after liver transplantation leads to an increased incidence and severity of ischemic biliary lesions in the rat model 认领 引用
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作者 Olaf Dirsch Haidong Chi +3 位作者 Yuan Ji Yan Li Gu Christoph E Broelsch Uta Dahmen 《World Journal of Gastroenterology》 SCIE CAS 2006年第31期5021-5027,共7页
AIM: Recently it has been reported that granulocyte colony stimulating factor (G-CSF) can induce hypercoagulability in healthy bone marrow donors. It is conceivable that the induction of a prothrombotic state in a ... AIM: Recently it has been reported that granulocyte colony stimulating factor (G-CSF) can induce hypercoagulability in healthy bone marrow donors. It is conceivable that the induction of a prothrombotic state in a recipient of an organ graft with already impaired perfusion might cause further deterioration in the transplanted organ. This study evaluated whether G-CSF treatment worsens liver perfusion following liver transplantation in the rat model. METHODS: A non-arterialized rat liver transplantation model was employed to evaluate the effect of G-CSF treatment on the liver in a syngeneic and allogeneic strain combination. Study outcomes included survival time and liver damage as investigated by liver enzymes and liver histology. Observation times were 1 d, 1 wk and 12 wk. RESULTS: Rats treated with G-CSF had increased incidence and severity of biliary damage following liver transplantation. In these animals, hepatocellular necrosis was accentuated in the centrilobular region. These lesions are indicative of impaired perfusion in G-CSF treated animals. CONCLUSION: G-CSF should be used with caution in recipients of liver transplantation, as treatment might enhance preexisting, undetected perfusion problems and ultimately lead to ischemia induced biliary complications . 展开更多
关键词 Granulocyte colony stimulating factor Ischemic biliary lesions Hypercoagulability Liver transplantation
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