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Bone and renal safety of initial antiviral therapy using tenofovir alafenamide fumarate or entecavir for chronic hepatitis B 认领 引用
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作者 Hui-Bin Ning Hui-Ming Jin +2 位作者 Zhen Peng Kuan Li Jia Shang 《World Journal of Gastroenterology》 SCIE CAS 2026年第22期45-52,共8页
BACKGROUND Nucleosideucleotide analogs are currently the core drugs for antiviral treatment of chronic hepatitis B(CHB).Among them,entecavir(ETV)and tenofovir alafenamide fumarate(TAF)exhibit potent antiviral effects ... BACKGROUND Nucleosideucleotide analogs are currently the core drugs for antiviral treatment of chronic hepatitis B(CHB).Among them,entecavir(ETV)and tenofovir alafenamide fumarate(TAF)exhibit potent antiviral effects with low resistance rates and are recommended as first-line treatment regimens in domestic and international guidelines.AIM To evaluate bone and renal safety in patients with CHB receiving initial treatment with TAF or ETV.METHODS This study included 95 treatment-naive patients with CHB and were treated at the Infectious Diseases Department of Henan Provincial People’s Hospital from August 2019 to June 2020.They were assigned to either the TAF group(n=45,25 mg/day)or the ETV group(n=50,0.5 mg/day)according to the antiviral treatment plan.Patients’basic clinical data were collected.Their bone mineral density,bone-related markers,and various renal function indicators were also measured and compared.RESULTS The study cohort had a mean age of 41.01±11.67 years and a cirrhosis prevalence of 18.9%.At baseline,serum Ca(2.33±0.13 vs 2.30±0.15,t=0.935,P=0.352),serum P(1.12±0.21 vs 1.12±0.19,t=0.026,P=0.980),and 25-hydroxyvitamin D3[25(OH)D](22.67±7.98 vs 24.96±11.30,t=1.122,P=0.265)were comparable across groups.When the follow-up was extended to 96W,the abnormality rates of urinary A1M(4.4%vs 20.0%,χ2=5.193,P=0.023),N-acetyl-beta-D-glucosaminidase(6.7%vs 24.0%,χ2=5.352,P=0.021),and urine cystatin(4.4%vs 18.0%,χ2=4.251,P=0.039)exhibited marked between-group differences.CONCLUSION For patients with CHB on long-term nucleoside drug use,comprehensive monitoring of bone and renal safety should be conducted as treatment duration increases.In this study,TAF outperforms ETV in renal tubular safety after long-term application. 展开更多
关键词 Chronic hepatitis B Entecavir Tenofovir alafenamide fumarate Bone safety Renal safety
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Deep Learning-Based Structural Displacement Identification and Quantification under Target Feature Loss 认领 引用
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作者 Lishuai Zhu Guangcai Zhang +4 位作者 Qun Xie Zhen Peng Li Ai Ruijun Liang Taochun Yang 《Structural Durability & Health Monitoring》 EI 2026年第2期57-77,共21页
Structural displacement monitoring faces significant challenges under complex environmental conditions due to the loss or degradation of target features,making it difficult for traditional methods to ensure high accur... Structural displacement monitoring faces significant challenges under complex environmental conditions due to the loss or degradation of target features,making it difficult for traditional methods to ensure high accuracy and robustness.Therefore,this study proposes a structural displacement identification and quantification method that integrates YOLOv8n with an improved edge-orientation gradient-based template matching algorithm.By combining deep learning techniques with traditional template matching methods,the accuracy and robustness of monitoring are enhanced under adverse conditions such as noise and extremely low illumination.Specifically,in the edge-orientation gradient matching stage,the Canny-Devernay sub-pixel edge detection technique and an improved ellipse-fitting method are employed for sub-pixel edge extraction,and a five-level Gaussian pyramid structure is introduced to accelerate the matching speed.Experimental results show that the proposed method achieves high-precision displacement monitoring under sufficient illumination,and it maintains stable target localization and displacement quantification performance under conditions of noise interference and extremely low illumination.Notably,under salt-and-pepper noise interference,although YOLOv8n maintains a high level of localization confidence,the accuracy of gradient matching deteriorates,resulting in a root-mean-square error(RMSE)of 0.035 mm.This finding reveals the differential impact of various noise types on different stages of the algorithm.The proposed method offers a novel technological approach for precise structural displacement monitoring in complex environments. 展开更多
关键词 Structural displacement quantification complex environments edge detection ellipse fitting template matching
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金黄色葡萄球菌血流感染的耐药特征及预后影响因素研究 认领 引用
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作者 甄鹏 胡明 +2 位作者 王胤颖 奥婷 黄英秀 《河北医药》 CAS 2026年第7期1207-1210,共4页
目的探讨金黄色葡萄球菌血流感染(SA-BSI)患者的耐药特征及影响预后的危险因素。方法回顾性分析2019至2024年北京潞河医院257例SA-BSI患者的临床资料,其中甲氧西林耐药金黄色葡萄球菌(MRSA组)感染者119例,甲氧西林敏感金黄色葡萄球菌(M... 目的探讨金黄色葡萄球菌血流感染(SA-BSI)患者的耐药特征及影响预后的危险因素。方法回顾性分析2019至2024年北京潞河医院257例SA-BSI患者的临床资料,其中甲氧西林耐药金黄色葡萄球菌(MRSA组)感染者119例,甲氧西林敏感金黄色葡萄球菌(MSSA组)感染者138例,入院28 d内死亡82例(死亡组),生存175例(生存组)。采用单因素分析、多因素Logistic回归分析等统计学方法,分析影响预后及MRSA血流感染的危险因素。结果MRSA组对β-内酰胺类、喹诺酮类、大环内酯类等多种抗生素敏感率显著低于MSSA组(P<0.05)。多因素Logistic回归分析表明,中心静脉置管留置超过14 d、90 d内广谱抗生素暴露史及院内感染是MRSA血流感染的危险因素。而Cox比例风险模型显示,MRSA感染是SA-BSI患者死亡的独立危险因素(OR=2.35,95%CI:1.04~5.32,P=0.041)。结论MRSA感染是金葡菌血流感染患者死亡的独立危险因素,其耐药性与中心静脉导管留置时间、抗生素的不合理应用及院内传播密切相关。临床应根据耐药危险因素,采取有针对性的防控干预措施,早期精准治疗,从而改善患者预后。 展开更多
关键词 金黄色葡萄球菌 血流感染 预后 耐药性 危险因素
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Recrystallization aspects and factors affecting their roles in Mg alloys:A comprehensive review 认领 引用 被引量：2
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作者 S.S.A.Shah Manping Liu +6 位作者 Azim Khan Farooq Ahmad Umer Masood Chaudry Muhammad Yar Khan M.R.Abdullah Shiwei Xu Zhen Peng 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2025年第5期1879-1914,共36页
Recrystallization stands as an essential process that influences the microstructure and properties of magnesium(Mg)alloys,yet its mechanisms remain complex and multifaceted.This review explores the key factors affecti... Recrystallization stands as an essential process that influences the microstructure and properties of magnesium(Mg)alloys,yet its mechanisms remain complex and multifaceted.This review explores the key factors affecting the recrystallization behavior of Mg alloys,emphasizing how their unique structural characteristics impact the driving forces and dynamics of recrystallization.Unlike conventional alloys,Mg alloys exhibit distinctive recrystallization kinetics,which is significantly affected by deformation conditions,such as strain rate,temperature,and processing methods(e.g.,rolling,forging,and extrusion).The process is also influenced by material characteristics,including initial grain size,texture,dislocation density,solute clustering,and stacking fault energy.Additionally,uneven strain distribution,stress concentrations,and stored energy play crucial roles in shaping the formation of recrystallized grains,particularly near grain boundaries.Notably,recrystallization is driven by dislocation accumulation and the availability of slip systems,with new strain-free grains typically forming in regions of high dislocation density.This paper synthesizes the existing literature to provide a comprehensive understanding of the mechanisms and kinetics of recrystallization in Mg alloys,highlighting the influence of microstructural features such as second-phase particles and grain boundary characteristics.It also identifies key challenges and suggests promising directions for future research,including optimizing material compositions and the interaction between deformation conditions via machine learning. 展开更多
关键词 Mg alloys Recrystallization Microstructural evolution Influencing factors Grain refinement Twinning
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Machine Memory Intelligence:Inspired by Human Memory Mechanisms 认领 引用 被引量：2
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作者 Qinghua Zheng Huan Liu +9 位作者 Xiaoqing Zhang Caixia Yan Xiangyong Cao Tieliang Gong Yong-Jin Liu Bin Shi Zhen Peng Xiaocen Fan Ying Cai Jun Liu 《Engineering》 SCIE EI CSCD 2025年第12期24-35,共12页
Large models,exemplified by ChatGPT,have reached the pinnacle of contemporary artificial intelligence(AI).However,they are plagued by three inherent drawbacks:excessive training data and computing power consumption,su... Large models,exemplified by ChatGPT,have reached the pinnacle of contemporary artificial intelligence(AI).However,they are plagued by three inherent drawbacks:excessive training data and computing power consumption,susceptibility to catastrophic forgetting,and a deficiency in logical reasoning capabilities within black-box models.To address these challenges,we draw insights from human memory mechanisms to introduce“machine memory,”which we define as a storage structure formed by encoding external information into a machine-representable and computable format.Centered on machine memory,we propose the brand-new machine memory intelligence(M2I)framework,which encompasses representation,learning,and reasoning modules and loops.We explore the key issues and recent advances in the four core aspects of M2I,including neural mechanisms,associative representation,continual learning,and collaborative reasoning within machine memory.M2I aims to liberate machine intelligence from the confines of data-centric neural networks and fundamentally break through the limitations of existing large models,driving a qualitative leap from weak to strong AI. 展开更多
关键词 Machine memory intelligence Neural mechanism Associative representation Continual learning Collaborative reasoning
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基于数字孪生的动车组PHM建模方法 认领 引用 被引量：1
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作者 吴奇 贾志凯 +3 位作者 朱晓敏 甄鹏 李燕 崔言杰 《中国铁路》 北大核心 2026年第1期43-50,共8页
为克服现有动车组故障预测与健康管理(PHM)在多源数据融合、动态工况适应性、模型泛化能力等方面的不足,基于数字孪生技术,提出适用于动车组的PHM系统建模与应用框架。该框架以物理层、数据层、模型与功能层、服务层为核心,结合多体动... 为克服现有动车组故障预测与健康管理(PHM)在多源数据融合、动态工况适应性、模型泛化能力等方面的不足,基于数字孪生技术,提出适用于动车组的PHM系统建模与应用框架。该框架以物理层、数据层、模型与功能层、服务层为核心,结合多体动力学仿真、实时数据同化、机器学习算法,实现对动车组关键系统(如牵引系统、转向架、空调系统等)的健康状态评估与精准故障预测。研究结果表明,构建的数字孪生PHM系统可有效提升故障预测的准确性,优化维护决策,通过视情维修策略,降低运维成本和维护作业负担。实际案例分析结果显示,该方法可在高速铁路复杂运行环境中实现更智能化、精细化的动车组运维管理,为高速铁路车辆全生命周期的安全可靠运行提供坚实的技术支撑。 展开更多
关键词 数字孪生 动车组 PHM 智能运维 建模方法
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沉浸式动车组检修作业辅助系统设计与关键技术研究 认领 引用
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作者 吕飞 甄鹏 +1 位作者 崔言杰 吴奇 《铁路计算机应用》 2026年第2期23-27,共5页
随着我国高速铁路网建设的持续加快,动车组检修业务复杂度增加,检修工作亟需智能化辅助手段。文章基于动车组检修培训与作业辅助2个方面的业务需求,设计了基于沉浸式技术的动车组检修作业辅助系统,融合了虚拟现实(VR,Virtual Reality)... 随着我国高速铁路网建设的持续加快,动车组检修业务复杂度增加,检修工作亟需智能化辅助手段。文章基于动车组检修培训与作业辅助2个方面的业务需求,设计了基于沉浸式技术的动车组检修作业辅助系统,融合了虚拟现实(VR,Virtual Reality)与增强现实(AR,Augmented Reality)技术。该系统以AR技术进行现场作业智能引导,以VR技术辅助模拟培训与考核,构建“训练-实战-反馈-优化训练”的检修能力提升闭环,为提升检修作业效率和作业人员技能水平提供技术支撑。 展开更多
关键词 动车组 检修培训 沉浸式技术 虚拟现实 增强现实
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Exploration and Practice of Collaborative Talent Cultivation Model for Urban Horticulture under the Background of Smart Agriculture 认领 引用 被引量：1
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作者 Zhen Peng Yuerong Gao +1 位作者 Ziyan Liu Liusheng Duan 《Journal of Contemporary Educational Research》 2025年第1期198-204,共7页
This paper discusses the development characteristics of urban horticulture under the background of smart agriculture,as well as the application of artificial intelligence technology in it.It analyzes the importance of... This paper discusses the development characteristics of urban horticulture under the background of smart agriculture,as well as the application of artificial intelligence technology in it.It analyzes the importance of highly skilled talents in urban agriculture in the era of smart agriculture and their cultivation pathways and practices.It proposes measures such as building multi-level practical teaching platforms,implementing the“Enjoy Horticulture”series of high-quality activities,and establishing the“1234”applied talent training model to cultivate high-quality talents that meet the development needs of modern urban horticulture industry.Taking Beijing University of Agriculture and other universities as examples,the paper analyzes the practical cases and effects of the urban horticulture discipline’s industry-education-research collaborative talent training model,which has reference significance for further improving and perfecting the urban horticulture industry-education-research collaborative talent training plan. 展开更多
关键词 Agricultural modernization Smart agriculture Urban horticulture Industry-education-research collaboration Talent cultivation
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基于数字孪生的动车组智能运维系统设计与关键技术研究 认领 引用 被引量：1
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作者 崔言杰 张惟皎 +2 位作者 甄鹏 王忠凯 李超旭 《铁路计算机应用》 2025年第12期33-37,共5页
针对传统动车组运营维护(简称:运维)模式在动态工况响应、故障诊断精度及维护时效性等方面的局限,设计基于数字孪生技术的动车组智能运维系统。文章通过构建“物理实体层-数据资源层-孪生虚拟层-智能服务层-业务决策层”5层架构,实现动... 针对传统动车组运营维护(简称:运维)模式在动态工况响应、故障诊断精度及维护时效性等方面的局限,设计基于数字孪生技术的动车组智能运维系统。文章通过构建“物理实体层-数据资源层-孪生虚拟层-智能服务层-业务决策层”5层架构,实现动车组全生命周期数据的多源整合与虚实协同映射;阐述高精度三维建模、动态行为仿真及多源异构数据实时传输等关键技术,以及实时监测、故障预警、仿真模拟与维修指导等核心功能。实际应用表明,该系统通过实时数据交互与可视化技术,提升了动车组状态监测透明度与故障预测能力,为科学决策提供精准依据,具有工程应用价值。 展开更多
关键词 数字孪生 动车组智能运维 三维建模 数据融合 运维决策
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Analysis of the Development Trends and Hotspots of Digital Transformation in China’s Vocational Education 认领 引用
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作者 Yuan Lv Na Yao +1 位作者 Zhen Peng Mingxu Zhou 《Journal of Contemporary Educational Research》 2025年第11期270-277,共8页
In recent years,with the rapid development of next-generation digital technologies,the vigorous growth of the digital economy,and the continuous deepening of the strategy to build a strong education nation,the digital... In recent years,with the rapid development of next-generation digital technologies,the vigorous growth of the digital economy,and the continuous deepening of the strategy to build a strong education nation,the digital transformation of vocational education has increasingly become a focal point.This trend has prompted researchers to delve into the background of digital transformation in vocational education,the current challenges and difficulties it faces,and actively seek effective pathways to enhance vocational education quality through digital transformation.It also explores how to better leverage the potential of digital technologies in educational services.Against this backdrop,this paper employs CiteSpace software to conduct a visual analysis of research literature related to digital transformation and vocational education,aiming to outline the research hotspots and evolutionary trends in this field.Based on the analysis results,the paper further proposes constructive suggestions and prospects for the future development direction of vocational education digital transformation. 展开更多
关键词 Digital transformation Vocational education Development insights
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Twinning aspects and their efficient roles in wrought Mg alloys:A comprehensive review 认领 引用 被引量：10
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作者 S.S.A.Shah Manping Liu +5 位作者 Azim Khan Farooq Ahmad M.R.Abdullah Xingquan Zhang Shiwei Xu Zhen Peng 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第6期2201-2230,共30页
Twinning is widely recognized as an effective and cost-efficient method for controlling the microstructure and properties of wrought magnesium(Mg)alloys.Specifically,twins play a crucial role in initiating dynamic rec... Twinning is widely recognized as an effective and cost-efficient method for controlling the microstructure and properties of wrought magnesium(Mg)alloys.Specifically,twins play a crucial role in initiating dynamic recrystallization(DRX),while twin regions experience rapid recrystallization during static recrystallization(SRX).The activation of twinning can lead to changes in lattice orientation,significantly impacting the final texture in Mg alloys.The active roles of twinning are influenced by various factors during the activation process,and the mobility of twin boundaries(TB)can be amplified by stress effects,dislocation interactions,and thermal effects.Conversely,annealing treatments that involve proper segregation or precipitation on TBs serve to stabilize them,restraining their motion.Events such as segregation may also alter the twinning propensity in Magnesium-rare earth(Mg-RE)alloys.While{10–11}contraction twins(CT)and{10–11}-{10–12}double twins(DT)can promote dynamic recrystallization(DRX),they also pose a risk as potential sources of voids and cracks.Additionally,understanding the nucleation and growth mechanisms of twinning is crucial,and these aspects are briefly reviewed in this article.Considering the factors mentioned above,this article summarizes the recent research progress in this field,shedding light on advancements in recent eras. 展开更多
关键词 Mg alloys Twinning Recrystallization Texture Mechanical properties
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Microstructure and mechanical properties of lightweight AlCrTiV0.5Cux high-entropy alloys 认领 引用 被引量：11
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作者 Zhen Peng Zai-Bin Luo +5 位作者 Bao-Wei Li Jin-Feng Li Heng-Wei Luan Jia-Lun Gu Yuan Wu Ke-Fu Yao 《Rare Metals》 SCIE EI CAS CSCD 2022年第6期2016-2020,共5页
High-entropy alloys(HEAs)are an emerging and rapidly developing family of alloys with appealing properties such as lightweight HEAs with excellent mechanical properties.In this study,to obtain lightweight HEAs with ex... High-entropy alloys(HEAs)are an emerging and rapidly developing family of alloys with appealing properties such as lightweight HEAs with excellent mechanical properties.In this study,to obtain lightweight HEAs with exceptional hardness,we prepared AlCrTiV0.5Cux(x=0,0.2,0.4,0.6,0.8 and 1.0,denoted as Cu0,Cu0.2,Cu0.4,Cu0.6,Cu0.8 and Cu1.0 alloys,respectively)HEAs and analyzed their microstructure and hardness. 展开更多
关键词 alloys properties. Microstructure
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Fe-based metallic glass as heterogeneous Fenton-like catalyst for azo dyes degradation:effect of inorganic anions 认领 引用 被引量：6
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作者 Ming-Jie Zhou Wen-Tao Zhang +4 位作者 Zhun Li Tao Feng Si Lan Zhen Peng Shuang-Qin Chen 《Rare Metals》 SCIE EI CAS CSCD 2023年第10期3443-3454,共12页
Metallic glasses(MGs) are promising heterogeneous catalysts in water remediation,due to their superior efficiency,selectivity,reusability and corrosion resistance.However,few works are focused on the influence of inor... Metallic glasses(MGs) are promising heterogeneous catalysts in water remediation,due to their superior efficiency,selectivity,reusability and corrosion resistance.However,few works are focused on the influence of inorganic anions that are abundant in wastewater.Herein,four common inorganic anions were added in a heterogeneous Fenton-like system(Fe-MG/H2O2) to study inorganic anions' influence on MGs' catalytic performance during methylene blue(MB) degradation.Evidence demonstrated that chloride ions and dihydrogen phosphate ions had an adverse effect on the catalytic performance of Fe-MG,whereas Fe-MG/H2O2 system sustained high efficiency in the presence of sulfate ions and nitrate ions during the Fenton-like process.By studying the structure,surface morphology,and evolution of active species,it was found that inorganic anions had a significant effect on the surface morphology of Fe-MG and the generation of active species.This work will provide essential references for MGs as heterogeneous catalysts in practical applications. 展开更多
关键词 Fe-based metallic glass(Fe–MG) Inorganic anion Wastewater treatment Methylene blue(MB)
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McMYB4 improves temperature adaptation by regulating phenylpropanoid metabolism and hormone signaling in apple 认领 引用 被引量：6
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作者 Suxiao Hao Yanfen Lu +4 位作者 Zhen Peng Enying Wang Linke Chao Silin Zhong Yuncong Yao 《Horticulture Research》 SCIE CSCD 2021年第1期2319-2332,共14页
Temperature changes affect apple development and production.Phenylpropanoid metabolism and hormone signaling play a crucial role in regulating apple growth and development in response to temperature changes.Here,we fo... Temperature changes affect apple development and production.Phenylpropanoid metabolism and hormone signaling play a crucial role in regulating apple growth and development in response to temperature changes.Here,we found that McMYB4 is induced by treatment at 28℃ and 18℃,and McMYB4 overexpression results in flavonol and lignin accumulation in apple leaves.Yeast one-hybrid(Y1H)assays and electrophoretic mobility shift assays(EMSAs)further revealed that McMYB4 targets the promoters of the flavonol biosynthesis genes CHS and FLS and the lignin biosynthesis genes CAD and F5H.McMYB4 expression resulted in higher levels of flavonol and lignin biosynthesis in apple during growth at 28℃ and 18℃ than during growth at 23℃.At 28℃ and 18℃,McMYB4 also binds to the AUX/ARF and BRI/BIN promoters to activate gene expression,resulting in acceleration of the auxin and brassinolide signaling pathways.Taken together,our results demonstrate that McMYB4 promotes flavonol biosynthesis and brassinolide signaling,which decreases ROS contents to improve plant resistance and promotes lignin biosynthesis and auxin signaling to regulate plant growth.This study suggests that McMYB4 participates in the abiotic resistance and growth of apple in response to temperature changes by regulating phenylpropanoid metabolism and hormone signaling. 展开更多
关键词 phenyl acceleration metabolism
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In situ study on medium-range order evolution during the polyamorphous phase transition in a Pd-Ni-P nanostructured glass 认领 引用 被引量：4
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作者 Shu Fu Sinan Liu +15 位作者 Jiacheng Ge Junjie Wang Huiqiang Ying Shangshu Wu Mengyang Yan Li Zhu Yubin Ke Junhua Luan Yang Ren Xiaobing Zuo Zhenduo Wu Zhen Peng Chain-Tsuan Liu Xun-Li Wang Tao Feng Si Lan 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2022年第30期145-156,共12页
Engineering multiscale structural hierarchies in glassy alloys enable a broad spectrum of potential applications.Metallic glasses were born in hierarchical structures from atomic-to-nanometer scales.However,the frozen... Engineering multiscale structural hierarchies in glassy alloys enable a broad spectrum of potential applications.Metallic glasses were born in hierarchical structures from atomic-to-nanometer scales.However,the frozen-in structures in traditional metallic glasses prepared by rapid quenching techniques are challenging to tailor.Here,we show that a PdNiPbulk nanostructured glass of polyamorphous interfacial structures was prepared by inert-gas condensation with a laser evaporation source,and its multiscale structures could be engineered.In-situ scattering experiment results reveal polyamorphous phase transitions occurred in the interfacial regions,which are accompanied by the evolution of medium-range order and the nanoscale heterogeneous structures during the condensation process of glassy nanoparticles under high pressure and the following heating process.Moreover,changes in the cluster connectivity resulting from repacking of the local ordering induced by pressure and temperature could be observed.The thermophysical and mechanical properties,including boson peaks,hardness,and elasticity modulus,could be changed as a function of heat-treatment parameters.Our findings would shed light on the synthesis of bulk nanostructured glassy alloys with tailorable thermodynamic and dynamical behavior as well as mechanical properties based on the understanding of metastability for polyamorphous interfacial phases. 展开更多
关键词 Bulk nanostructured glasses Medium-range order Polyamorphous phase transition
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Fe-based multi-phase nanocrystalline ribbons with hierarchically flowerlike structured metal oxides after modified by Orange II for Cr^VI absorption 认领 引用 被引量：1
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作者 Shuang-qin Chen Liang-zheng Dong +5 位作者 Ke-zhen Hui Zhen Peng Zhun Li Zhi-Chao Lu Yang Shao Ke-fu Yao 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2018年第6期608-613,共6页
Three-dimensional flowerlike nanostructured metal oxides attached on the surfaces of Fe-based multi-phase nanocrys- talline ribbons （Fe-MNRs） were prepared by a simple way （through immersing the Fe-MNRs in Orange I... Three-dimensional flowerlike nanostructured metal oxides attached on the surfaces of Fe-based multi-phase nanocrys- talline ribbons （Fe-MNRs） were prepared by a simple way （through immersing the Fe-MNRs in Orange II solution）. It has been found that the as-prepared Fe-MNRs with 3D flowerlike nanostructures （Fe-MNRs ＋ FNs） exhibit good absorption property for a typical heavy metal ion （Cr^VI） in wastewater, while Fe-MNRs do not possess such properties. The Fe-MNRs ＋ FNs could remove 99% CrvI ions from the solution in 40 min, and this adsorption property can be attributed to the ion exchange between Cr^VI and surface hydroxyl groups （O-H） of 3D flowerlike nanostructures. The present result suggests that the Fe-MNRs ＋ FNs, prepared by facile way, possess great potentials in removing heavy metallic ions in wastewater. 展开更多
关键词 Fe-based multi-phase nanocrystalline ribbon Flowerlike nanostructure α-FeO（OH） Hexavalent chromium Wastewater treatment
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六个繁育场异育银鲫的克隆系鉴定及特征分析 认领 引用 被引量：1
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作者 杨涵 龚艺 +7 位作者 甄鹏 谢明花 刘敏 周于琳 李熙银 周莉 桂建芳 王忠卫 《水生生物学报》 CAS CSCD 北大核心 2025年第2期156-166,共11页
为了厘清湖北省异育银鲫(Carassius gibelio)繁殖群体的种质资源现状,研究以湖北省6个苗种繁殖场的异育银鲫亲本为研究对象,比较不同群体的生物学特征和品质性状的差异,利用基因组重测序进行品种与克隆系鉴定和遗传多样性分析。研究结... 为了厘清湖北省异育银鲫(Carassius gibelio)繁殖群体的种质资源现状,研究以湖北省6个苗种繁殖场的异育银鲫亲本为研究对象,比较不同群体的生物学特征和品质性状的差异,利用基因组重测序进行品种与克隆系鉴定和遗传多样性分析。研究结果表明,根据180尾异育银鲫全基因组重测序的SNPs,共鉴定出10个异育银鲫克隆系,其中2个异育银鲫“中科3号”亚克隆系,5个异育银鲫“中科5号”亚克隆系和3个其他克隆系。遗传多样性分析表明,单核苷酸密度(SNP/kb)、单核苷酸多态性(p)、多态信息含量(PIC)和观测杂合度(Ho)分别为11.17、0.0050、0.4332和0.5612。系统发育树和主成分分析结果显示,不同群体之间表现出中度到高度的遗传分化,同时也存在较为显著的交叉聚类现象,结合异育银鲫克隆系分布,表明除了梁子湖和正大群体外的繁殖亲本存在一定的种质混杂现象。不同克隆系之间的形态上存在差异,体高/体长和头长/体长可以作为初步判断异育银鲫形态的两个参考指标。异育银鲫“中科5号”和异育银鲫“中科3号”的肌肉营养成分中粗脂肪含量差异显著,而粗蛋白含量无明显差异。不同克隆系间的肌肉中17种脂肪酸含量均存在显著差异,DHA+EPA总量在不同克隆系之间也存在差异。研究不仅有利于异育银鲫种质资源的合理开发与保护,而且有助于异育银鲫新品种选育和养殖产业的可持续发展。 展开更多
关键词 种质资源 克隆鉴定 营养成分 遗传多样性 异育银鲫
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Genetic dissection and origin of pleiotropic loci underlying multilevel fiber quality traits in upland cotton(Gossypium hirsutum L.) 认领 引用 被引量：1
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作者 Hongge Li Shurong Tang +7 位作者 Zhen Peng Guoyong Fu Yinhua Jia Shoujun Wei Baojun Chen Muhammad Shahid Iqbal Shoupu He Xiongming Du 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第10期3250-3263,共14页
Cotton fiber quality is a persistent concern that determines planting benefits and the quality of finished textile products.However,the limitations of measurement instruments have hindered the accurate evaluation of s... Cotton fiber quality is a persistent concern that determines planting benefits and the quality of finished textile products.However,the limitations of measurement instruments have hindered the accurate evaluation of some important fiber characteristics such as fiber maturity,fineness,and neps,which in turn has impeded the genetic improvement and industrial utilization of cotton fiber.Here,12 single fiber quality traits were measured using Advanced Fiber Information System(AFIS)equipment among 383 accessions of upland cotton(Gossypium hirsutum L.).In addition,eight conventional fiber quality traits were assessed by the High Volume Instrument(HVI)System.Genome-wide association study(GWAS),linkage disequilibrium(LD)block genotyping and functional identification were conducted sequentially to uncover the associated elite loci and candidate genes of fiber quality traits.As a result,the previously reported pleiotropic locus FL_D11 regulating fiber length-related traits was identified in this study.More importantly,three novel pleiotropic loci(FM_A03,FF_A05,and FN_A07)regulating fiber maturity,fineness and neps,respectively,were detected based on AFIS traits.Numerous highly promising candidate genes were screened out by integrating RNA-seq and qRT-PCR analyses,including the reported GhKRP6 for fiber length,the newly identified GhMAP8 for maturity and GhDFR for fineness.The origin and evolutionary analysis of pleiotropic loci indicated that the selection pressure on FL_D11,FM_A03 and FF_A05 increased as the breeding period approached the present and the origins of FM_A03 and FF_A05 were traced back to cotton landraces.These findings reveal the genetic basis underlying fiber quality and provide insight into the genetic improvement and textile utilization of fiber in G.hirsutum. 展开更多
关键词 upland cotton single fiber quality pleiotropic loci candidate genes locus origin
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Tunable biasing magnetic field design of ferrite tuner for ICRF heating system in EAST 认领 引用 被引量：1
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作者 Manman XU Yuntao SONG +4 位作者 Gen CHEN Yanping ZHAO Yuzhou MAO Guang LIU Zhen PENG 《Plasma Science and Technology》 SCIE EI CAS CSCD 2017年第11期82-91,共10页
Ion cyclotron range of frequency（ICRF） heating has been used in tokamaks as one of the most successful auxiliary heating tools and has been adopted in the EAST. However, the antenna load will fluctuate with the chan... Ion cyclotron range of frequency（ICRF） heating has been used in tokamaks as one of the most successful auxiliary heating tools and has been adopted in the EAST. However, the antenna load will fluctuate with the change of plasma parameters in the ICRF heating process. To ensure the steady operation of the ICRF heating system in the EAST, fast ferrite tuner（FFT） has been carried out to achieve real-time impedance matching. For the requirements of the FFT impedance matching system, the magnet system of the ferrite tuner（FT） was designed by numerical simulations and experimental analysis, where the biasing magnetic circuit and alternating magnetic circuit were the key researched parts of the ferrite magnet. The integral design goal of the FT magnetic circuit is that DC bias magnetic field is 2000 Gs and alternating magnetic field is±400 Gs. In the FTT, E-type magnetic circuit was adopted. Ferrite material is Nd Fe B with a thickness of 30 mm by setting the working point of Nd Fe B, and the ampere turn of excitation coil is 25 through the theoretical calculation and simulation analysis. The coil inductance to generate alternating magnetic field is about 7 m H. Eddy-current effect has been analyzed, while the magnetic field distribution has been measured by a Hall probe in the medium plane of the biasing magnet. Finally, the test results show the good performance of the biasing magnet satisfying the design and operating requirements of the FFT. 展开更多
关键词 EAST ICRF heating ferrite tuner biasing magnet
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Spermidine affects the transcriptome responses to high temperature stress in ripening tomato fruit 认领 引用 被引量：2
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作者 Lin CHENG Rong-rong SUN +5 位作者 Fei-yan WANG Zhen PENG Fu-ling KONG Jian WU Jia-shu CAO Gang LU 《Journal of Zhejiang University-SCIENCE B》 SCIE CAS CSCD 2012年第4期283-297,共15页
Objective:High temperature adversely affects quality and yield of tomato fruit.Polyamine can alleviate heat injury in plants.This study is aimed to investigate the effects of polyamine and high temperature on transcri... Objective:High temperature adversely affects quality and yield of tomato fruit.Polyamine can alleviate heat injury in plants.This study is aimed to investigate the effects of polyamine and high temperature on transcriptional profiles in ripening tomato fruit.Methods:An Affymetrix tomato microarray was used to evaluate changes in gene expression in response to exogenous spermidine(Spd,1 mmol/L) and high temperature(33/27 °C) treatments in tomato fruits at mature green stage.Results:Of the 10 101 tomato probe sets represented on the array,127 loci were differentially expressed in high temperature-treated fruits,compared with those under normal conditions,functionally characterized by their involvement in signal transduction,defense responses,oxidation reduction,and hormone re-sponses.However,only 34 genes were up-regulated in Spd-treated fruits as compared with non-treated fruits,which were involved in primary metabolism,signal transduction,hormone responses,transcription factors,and stress re-sponses.Meanwhile,55 genes involved in energy metabolism,cell wall metabolism,and photosynthesis were down-regulated in Spd-treated fruits.Conclusions:Our results demonstrated that Spd might play an important role in regulation of tomato fruit response to high temperature during ripening stage. 展开更多
关键词 Solanum Ivcooersicum L.. Soermidine. Hioh temperature. Microarrav. Gene exDression
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