目的·比较分析达芬奇机器人与腹腔镜在儿童肠系膜囊肿切除术应用中的短期效果。方法·回顾性分析2020年1月至2025年8月于浙江大学医学院附属儿童医院普外科行达芬奇机器人辅助和腹腔镜辅助肠系膜囊肿切除术的71例患儿临床资料...目的·比较分析达芬奇机器人与腹腔镜在儿童肠系膜囊肿切除术应用中的短期效果。方法·回顾性分析2020年1月至2025年8月于浙江大学医学院附属儿童医院普外科行达芬奇机器人辅助和腹腔镜辅助肠系膜囊肿切除术的71例患儿临床资料,根据手术方式不同,将患儿分为达芬奇手术组(n=33)和腹腔镜手术组(n=38)。对比分析2组的一般资料、手术时间、术中出血量、手术完成方式、囊肿位置、囊肿最大径、术后禁食时间、术后住院时间以及术后并发症等指标,分析2种方法的优劣。结果·一般资料比较结果显示,2组患儿性别、月龄、体质量、临床症状、囊肿位置、囊肿最大径等方面的差异均无统计学意义(均P>0.05)。在手术完成方式方面,达芬奇手术组33例(100%)患儿全部在腹腔内完成囊肿剥离或肠切除及肠吻合;腹腔镜手术组仅有3例(7.9%)全部手术操作在腹腔内完成,其他病例均在腹腔外完成。2组手术完成方式构成比差异有统计学意义(P0.05),但达芬奇手术组的术中出血量显著少于腹腔镜手术组[5(2,5)mL vs 6(5,10)mL,P<0.001],术后住院时间也较短[9(7,11)d vs 10.5(8,13)d,P=0.033]。达芬奇手术组患儿未见明显并发症;腹腔镜手术组则有1例患儿术中出现输尿管损伤,1例术后出现乳糜瘘。所有患儿出院后随访6个月均恢复良好,未见囊肿复发。结论·与腹腔镜相比,达芬奇机器人手术治疗儿童肠系膜囊肿可显著提升完全腹腔内操作比例,且具有术中出血更少、术后恢复更快的特点,短期疗效确切、安全性良好。展开更多
动脉瘤样骨囊肿(aneurysmal bone cyst,ABC)常发生于儿童和青少年的长骨,起源于颅骨的ABC相对少见。本文报道河南大学淮河医院神经外科收治的1例6岁儿童右侧枕骨囊性病变患者,结合影像学、病理特点及泛素特异性蛋白酶(ubiquitin-specifi...动脉瘤样骨囊肿(aneurysmal bone cyst,ABC)常发生于儿童和青少年的长骨,起源于颅骨的ABC相对少见。本文报道河南大学淮河医院神经外科收治的1例6岁儿童右侧枕骨囊性病变患者,结合影像学、病理特点及泛素特异性蛋白酶(ubiquitin-specific protease 6,USP6)基因检测结果,最终诊断为右侧枕骨原发性ABC。本文围绕颅骨ABC的临床表现、CT和MRI影像学形态、鉴别诊断及病理特点进行总结,并复习相关文献,强调组织形态学、基因检测及影像学相结合对正确诊断ABC的重要性。展开更多
Pediatric liver transplantation(pLT)has evolved from a purely life-saving intervention into a therapeutic strategy associated with excellent long-term survival,with the majority of recipients now reaching adulthood.As...Pediatric liver transplantation(pLT)has evolved from a purely life-saving intervention into a therapeutic strategy associated with excellent long-term survival,with the majority of recipients now reaching adulthood.As survival outcomes have improved,the focus has progressively shifted from post-transplant survival alone to the pursuit of overall health.This concept encompasses optimal graft function,the absence of significant medical comorbidities,psychological well-being,social integration,and good quality of life,and should be regarded as the ideal long-term outcome after pLT.However,only a minority of patients currently achieve this goal,mainly due to liver-related,often immune-mediated,or extrahepatic medical complications,as well as psychosocial challenges.This minireview summarizes the key factors that limit the attainment of such an endpoint,critically discussing the limitations of currently used diagnostic parameters,and highlights existing challenges and unmet needs.Finally,potential multilevel strategies are proposed,including the implementation of structured and universal transition processes,the incorporation of novel diagnostic and prognostic biomarkers of graft function,and the prevention and early treatment of modifiable risk factors for extrahepatic complications,aimed at enabling the achievement of overall health in the majority of pLT recipients reaching adulthood in the near future.展开更多
摘要目的·比较分析达芬奇机器人与腹腔镜在儿童肠系膜囊肿切除术应用中的短期效果。方法·回顾性分析2020年1月至2025年8月于浙江大学医学院附属儿童医院普外科行达芬奇机器人辅助和腹腔镜辅助肠系膜囊肿切除术的71例患儿临床资料,根据手术方式不同,将患儿分为达芬奇手术组(n=33)和腹腔镜手术组(n=38)。对比分析2组的一般资料、手术时间、术中出血量、手术完成方式、囊肿位置、囊肿最大径、术后禁食时间、术后住院时间以及术后并发症等指标,分析2种方法的优劣。结果·一般资料比较结果显示,2组患儿性别、月龄、体质量、临床症状、囊肿位置、囊肿最大径等方面的差异均无统计学意义(均P>0.05)。在手术完成方式方面,达芬奇手术组33例(100%)患儿全部在腹腔内完成囊肿剥离或肠切除及肠吻合;腹腔镜手术组仅有3例(7.9%)全部手术操作在腹腔内完成,其他病例均在腹腔外完成。2组手术完成方式构成比差异有统计学意义(P0.05),但达芬奇手术组的术中出血量显著少于腹腔镜手术组[5(2,5)mL vs 6(5,10)mL,P<0.001],术后住院时间也较短[9(7,11)d vs 10.5(8,13)d,P=0.033]。达芬奇手术组患儿未见明显并发症;腹腔镜手术组则有1例患儿术中出现输尿管损伤,1例术后出现乳糜瘘。所有患儿出院后随访6个月均恢复良好,未见囊肿复发。结论·与腹腔镜相比,达芬奇机器人手术治疗儿童肠系膜囊肿可显著提升完全腹腔内操作比例,且具有术中出血更少、术后恢复更快的特点,短期疗效确切、安全性良好。
摘要动脉瘤样骨囊肿(aneurysmal bone cyst,ABC)常发生于儿童和青少年的长骨,起源于颅骨的ABC相对少见。本文报道河南大学淮河医院神经外科收治的1例6岁儿童右侧枕骨囊性病变患者,结合影像学、病理特点及泛素特异性蛋白酶(ubiquitin-specific protease 6,USP6)基因检测结果,最终诊断为右侧枕骨原发性ABC。本文围绕颅骨ABC的临床表现、CT和MRI影像学形态、鉴别诊断及病理特点进行总结,并复习相关文献,强调组织形态学、基因检测及影像学相结合对正确诊断ABC的重要性。
摘要Pediatric liver transplantation(pLT)has evolved from a purely life-saving intervention into a therapeutic strategy associated with excellent long-term survival,with the majority of recipients now reaching adulthood.As survival outcomes have improved,the focus has progressively shifted from post-transplant survival alone to the pursuit of overall health.This concept encompasses optimal graft function,the absence of significant medical comorbidities,psychological well-being,social integration,and good quality of life,and should be regarded as the ideal long-term outcome after pLT.However,only a minority of patients currently achieve this goal,mainly due to liver-related,often immune-mediated,or extrahepatic medical complications,as well as psychosocial challenges.This minireview summarizes the key factors that limit the attainment of such an endpoint,critically discussing the limitations of currently used diagnostic parameters,and highlights existing challenges and unmet needs.Finally,potential multilevel strategies are proposed,including the implementation of structured and universal transition processes,the incorporation of novel diagnostic and prognostic biomarkers of graft function,and the prevention and early treatment of modifiable risk factors for extrahepatic complications,aimed at enabling the achievement of overall health in the majority of pLT recipients reaching adulthood in the near future.