Objective To evaluate the feasibility of using a low concentration of contrast medium (Visipaque 270 mgl/mL), low tube voltage, and an advanced image reconstruction algorithm in head and neck computed tomography ang...Objective To evaluate the feasibility of using a low concentration of contrast medium (Visipaque 270 mgl/mL), low tube voltage, and an advanced image reconstruction algorithm in head and neck computed tomography angiography (CTA). Methods Forty patients (22 men and 18 women; average age 48.7 ± 14.25 years; average body mass index 23.9 ± 3.7 kg/m^2) undergoing CTA for suspected vascular diseases were randomly assigned into two groups. Group A (n = 20) was administered 370 mgl/mL contrast medium, and group B (n = 20) was administered 270 mgl/mL contrast medium. Both groups were administered at a rate of 4.8 mL/s and an injection volume of 0.8 mL/kg. Images of group A were obtained with 120 kVp and filtered back projection (FBP) reconstruction, whereas images of group B were obtained with 80 kVp and 80% adaptive iterative statistical reconstruction algorithm (ASiR). The CT values and standard deviations of intracranial arteries and image noise on the corona radiata were measured to calculate the contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR). The beam-hardening artifacts (BHAs) around the skull base were calculated. Two readers evaluated the image quality with volume rendered images using scores from 1 to 5. The values between the two groups were statistically compared. Results The mean CT value of the intracranial arteries in group B was significantly higher than that in group A (P 〈 0.001). The CNR and SNR values in group B were also statistically higher than those in group A (P 〈 0.001). Image noise and BHAs were not significantly different between the two groups. The image quality score of VR images of in group B was significantly higher than that in group A (P = 0.001). However, the quality scores of axial enhancement images in group B became significantly smaller than those in group A (P〈 0.001). The CT dose index volume and dose-length product were decreased by 63.8% and 64%, respectively, in group B (P 〈 0.001 for both). Conclusion Visipaque combined with 80 kVp and 80% ASiR provided similar image quality in intracranial CTA with 64% radiation dose reduction compared with the use of lopamidol, 120 kVp, and FBP reconstruc-tion.展开更多
Background Currently there is a trend towards reducing radiation dose while maintaining image quality during computer tomography(CT)examination.This results from the concerns about radiation exposure from CT and the p...Background Currently there is a trend towards reducing radiation dose while maintaining image quality during computer tomography(CT)examination.This results from the concerns about radiation exposure from CT and the potential increase in the incidence of radiation induced carcinogenesis.This study aimed to investigate the lowest radiation dose for maintaining good image quality in adult chest scanning using GE CT equipment.Methods Seventy-two adult patients were examined by Gemstone Spectral CT.They were randomly divided into six groups.We set up a different value of noise index(NI)when evaluating each group every other number from 13.0 to 23.0.The original images were acquired with a slice of 5 mm thickness.For each group,several image series were reconstructed using different levels of adaptive statistical iterative reconstruction(ASIR)(30%,50%,and 70%).We got a total of 18 image sequences of different combinations of NI and ASIR percentage.On one hand,quantitative indicators,such as CT value and standard deviation(SD),were assessed at the region of interest.The signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)were calculated.The volume CT dose index(CTDI)and dose length product(DLP)were recorded.On the other hand,two radiologists with>5 years of experience blindly reviewed the subjective image quality using the standards we had previously set.Results The different combinations of noise index and ASIR were assessed.There was no significant difference in CT values among the 18 image sequences.The SD value was reduced with the noise index's reduction or ASIR's increase.There was a trend towards gradually lower SNR and CNR with an NI increase.The CTDI and DLP were diminishing as the NI increased.The scores from subjective image quality evaluation were reduced in all groups as the ASIR increased.Conclusions Increasing NI can reduce radiation dose.With the premise of maintaining the same image quality,using a suitable percentage of ASIR can increase the value of NI.To assure image quality,we concluded that when the NI was set at 17.0 and ASlR was 50%,the image quality could be optimal for not only satisfying the requirements of clinical diagnosis,but also achieving the purpose of low-dose scanning.展开更多
目的探讨适应性统计迭代算法(ASIR)结合自动管电流调制技术在降低泌尿系CT扫描剂量中的应用价值。方法对2014年9月至2015年3月安徽医科大学第一附属医院25例拟行泌尿系CT平扫患者,设定管电压120 k V,使用自动毫安调制技术,管电流范围10~...目的探讨适应性统计迭代算法(ASIR)结合自动管电流调制技术在降低泌尿系CT扫描剂量中的应用价值。方法对2014年9月至2015年3月安徽医科大学第一附属医院25例拟行泌尿系CT平扫患者,设定管电压120 k V,使用自动毫安调制技术,管电流范围10~400 m A,螺距1.375∶1,球管转速0.5 r/s,先后行常规组及低剂量组扫描,预设常规组噪声指数(NI)为13,低剂量组NI为25。常规组及低剂量组同时使用1.25 mm层厚重建(定义常规组1.25 mm层厚为A组,低剂量组1.25 mm层厚为B组)并分别应用5种不同权重ASIR水平(0、20%、40%、60%、80%)进行图像重建,获得A1~A5、B1~B5共计10组图像,分别测量10个组图像在肝右叶、L1椎弓根水平腹主动脉噪声值及同层面肾门区肾实质CT值(HU),并计算信噪比(SNR)。记录两组扫描患者接受的容积CT剂量指数(CTDIvol)、剂量长度乘积(DLP)和有效剂量(ED)。并由2名具有5年以上腹部诊断经验的医师采用盲法对图像质量进行评估(5分制),采用Wilcoxon符号秩和检验及配对t检验进行统计学分析。结果常规组CTDIvol为(8.44±1.97)m Gy,ED为(6.13±1.55)m Sv;低剂量组CTDIvol为(2.46±0.70)m Gy,ED为(1.79±0.54)m Sv,两组差异有统计学意义(P<0.05),两组比较平均辐射剂量降低约70%。两组图像质量主观评分≥3分均能满足临床诊断要求。随着ASIR权重系数的增加,图像噪声值逐渐下降,SNR逐渐提高。结论使用ASIR算法结合自动管电流调制技术进行泌尿系低剂量CT扫描,可以在获得满足临床诊断需要的图像质量同时,大幅度降低患者受检的辐射剂量,具有较好的临床可行性。展开更多
目的探讨双高权重自适应统计迭代重建(ASIR-V)冠状动脉CT血管成像(CCTA)联合人工智能(AI)评估冠心病(CHD)的临床价值。方法前瞻性将124例行CCTA的疑似冠心病(CHD)患者以常规CCTA参数,噪声指数(NI)11,前、后置ASIR-V 50%为对照组,以高权...目的探讨双高权重自适应统计迭代重建(ASIR-V)冠状动脉CT血管成像(CCTA)联合人工智能(AI)评估冠心病(CHD)的临床价值。方法前瞻性将124例行CCTA的疑似冠心病(CHD)患者以常规CCTA参数,噪声指数(NI)11,前、后置ASIR-V 50%为对照组,以高权重后置ASIR-V 90%,前置ASIR-V分别为60%、70%、80%作为实验组。对图像质量进行5分法主观评分,计算信噪比(SNR)、对比噪声比(CNR)、有效剂量(ED),对比各组图像间的主观评分、噪声(SD)、SNR、CNR、ED。优化出图像质量高而ED低的组别进行AI分析,以冠状动脉造影(CAG)结果为金标准,血管狭窄程度≥50%记为阳性,绘制受试者工作特征(ROC)曲线,评估AI的诊断效能。结果对照组与前置ASIR-V 80%组的主观评分(4.61±0.50 vs 4.26±0.58)、SD(36.15±6.82 vs 42.08±7.98)、AR SNR(13.56±3.51 vs 11.26(8.67,13.02))、AR CNR(11.50±3.14 vs 9.52±2.70)、RCA SNR(12.82±3.29 vs 10.40(8.18,12.06))、RCA CNR(10.76±2.93 vs 8.75±2.59)、LCX SNR(12.45±3.26 vs 10.35±2.56)组间差异有统计学意义(P均<0.05),对照组的SD低于前置ASIR-V 80%组,其余参数值高于前置ASIR-V 80%组。优化组为前置ASIR-V 70%组,其AI分析结果对诊断血管狭窄程度≥50%的AUC为0.911,敏感度为0.935,特异度为0.888,阳性预测值为0.811,阴性预测值为0.963,准确率为0.904。结论后置ASIR-V 90%,前置ASIR-V 70%的CCTA参数能够保证图像质量的同时降低辐射剂量,其AI分析结果对诊断CHD有高诊断价值。展开更多
摘要Objective To evaluate the feasibility of using a low concentration of contrast medium (Visipaque 270 mgl/mL), low tube voltage, and an advanced image reconstruction algorithm in head and neck computed tomography angiography (CTA). Methods Forty patients (22 men and 18 women; average age 48.7 ± 14.25 years; average body mass index 23.9 ± 3.7 kg/m^2) undergoing CTA for suspected vascular diseases were randomly assigned into two groups. Group A (n = 20) was administered 370 mgl/mL contrast medium, and group B (n = 20) was administered 270 mgl/mL contrast medium. Both groups were administered at a rate of 4.8 mL/s and an injection volume of 0.8 mL/kg. Images of group A were obtained with 120 kVp and filtered back projection (FBP) reconstruction, whereas images of group B were obtained with 80 kVp and 80% adaptive iterative statistical reconstruction algorithm (ASiR). The CT values and standard deviations of intracranial arteries and image noise on the corona radiata were measured to calculate the contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR). The beam-hardening artifacts (BHAs) around the skull base were calculated. Two readers evaluated the image quality with volume rendered images using scores from 1 to 5. The values between the two groups were statistically compared. Results The mean CT value of the intracranial arteries in group B was significantly higher than that in group A (P 〈 0.001). The CNR and SNR values in group B were also statistically higher than those in group A (P 〈 0.001). Image noise and BHAs were not significantly different between the two groups. The image quality score of VR images of in group B was significantly higher than that in group A (P = 0.001). However, the quality scores of axial enhancement images in group B became significantly smaller than those in group A (P〈 0.001). The CT dose index volume and dose-length product were decreased by 63.8% and 64%, respectively, in group B (P 〈 0.001 for both). Conclusion Visipaque combined with 80 kVp and 80% ASiR provided similar image quality in intracranial CTA with 64% radiation dose reduction compared with the use of lopamidol, 120 kVp, and FBP reconstruc-tion.
摘要Background Currently there is a trend towards reducing radiation dose while maintaining image quality during computer tomography(CT)examination.This results from the concerns about radiation exposure from CT and the potential increase in the incidence of radiation induced carcinogenesis.This study aimed to investigate the lowest radiation dose for maintaining good image quality in adult chest scanning using GE CT equipment.Methods Seventy-two adult patients were examined by Gemstone Spectral CT.They were randomly divided into six groups.We set up a different value of noise index(NI)when evaluating each group every other number from 13.0 to 23.0.The original images were acquired with a slice of 5 mm thickness.For each group,several image series were reconstructed using different levels of adaptive statistical iterative reconstruction(ASIR)(30%,50%,and 70%).We got a total of 18 image sequences of different combinations of NI and ASIR percentage.On one hand,quantitative indicators,such as CT value and standard deviation(SD),were assessed at the region of interest.The signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)were calculated.The volume CT dose index(CTDI)and dose length product(DLP)were recorded.On the other hand,two radiologists with>5 years of experience blindly reviewed the subjective image quality using the standards we had previously set.Results The different combinations of noise index and ASIR were assessed.There was no significant difference in CT values among the 18 image sequences.The SD value was reduced with the noise index's reduction or ASIR's increase.There was a trend towards gradually lower SNR and CNR with an NI increase.The CTDI and DLP were diminishing as the NI increased.The scores from subjective image quality evaluation were reduced in all groups as the ASIR increased.Conclusions Increasing NI can reduce radiation dose.With the premise of maintaining the same image quality,using a suitable percentage of ASIR can increase the value of NI.To assure image quality,we concluded that when the NI was set at 17.0 and ASlR was 50%,the image quality could be optimal for not only satisfying the requirements of clinical diagnosis,but also achieving the purpose of low-dose scanning.
摘要目的探讨双高权重自适应统计迭代重建(ASIR-V)冠状动脉CT血管成像(CCTA)联合人工智能(AI)评估冠心病(CHD)的临床价值。方法前瞻性将124例行CCTA的疑似冠心病(CHD)患者以常规CCTA参数,噪声指数(NI)11,前、后置ASIR-V 50%为对照组,以高权重后置ASIR-V 90%,前置ASIR-V分别为60%、70%、80%作为实验组。对图像质量进行5分法主观评分,计算信噪比(SNR)、对比噪声比(CNR)、有效剂量(ED),对比各组图像间的主观评分、噪声(SD)、SNR、CNR、ED。优化出图像质量高而ED低的组别进行AI分析,以冠状动脉造影(CAG)结果为金标准,血管狭窄程度≥50%记为阳性,绘制受试者工作特征(ROC)曲线,评估AI的诊断效能。结果对照组与前置ASIR-V 80%组的主观评分(4.61±0.50 vs 4.26±0.58)、SD(36.15±6.82 vs 42.08±7.98)、AR SNR(13.56±3.51 vs 11.26(8.67,13.02))、AR CNR(11.50±3.14 vs 9.52±2.70)、RCA SNR(12.82±3.29 vs 10.40(8.18,12.06))、RCA CNR(10.76±2.93 vs 8.75±2.59)、LCX SNR(12.45±3.26 vs 10.35±2.56)组间差异有统计学意义(P均<0.05),对照组的SD低于前置ASIR-V 80%组,其余参数值高于前置ASIR-V 80%组。优化组为前置ASIR-V 70%组,其AI分析结果对诊断血管狭窄程度≥50%的AUC为0.911,敏感度为0.935,特异度为0.888,阳性预测值为0.811,阴性预测值为0.963,准确率为0.904。结论后置ASIR-V 90%,前置ASIR-V 70%的CCTA参数能够保证图像质量的同时降低辐射剂量,其AI分析结果对诊断CHD有高诊断价值。