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Cariprazine modulates affective and social behaviors through ventral striatal islands of Calleja neurons 认领 引用
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作者 Zhangwei Song Wenqiang Wang +4 位作者 Haiping Wang Yanbiao Zhong Guanqing Li Ruiyi Tan Yun-Feng Zhang 《Current Zoology》 SCIE CAS CSCD 2026年第2期198-210,共13页
Cariprazine,a dopamine D2/D3 receptor partial agonist with high affinity for D3 receptors,is effective in treating bipolar disorder and depression;however,the precise neural mechanisms underlying its actions remain in... Cariprazine,a dopamine D2/D3 receptor partial agonist with high affinity for D3 receptors,is effective in treating bipolar disorder and depression;however,the precise neural mechanisms underlying its actions remain incompletely understood.This study investigates how cariprazine modulates affective and social behaviors through D3 neurons in the olfactory tubercle(OT).Local infusion of cariprazine specifically into the OT,but not the nucleus accumbens(NAc)or hippocampus,induced anxiety-like behaviors,impaired struggling behaviors in depression-related tests,and increased huddling behavior,a measure of thermoregulation and social interaction.These behavioral changes were associated with decreased D3 neuronal activity in the OT,as evidenced by whole-cell patch-clamp recordings.Optogenetic activation of OT D3 neurons normalized cariprazine-induced anxiety-like behaviors and blunted the increase in struggling and huddling behavior.Additionally,cariprazine administration elevated body temperature,likely due to enhanced huddling behavior.These findings underscore the critical role of OT D3 neurons in mediating cariprazine’s effects on affective and social behaviors,providing new insights into the neural mechanisms underlying its therapeutic actions and the involvement of ventral striatal D3 neurons in neuropsychiatric disorders. 展开更多
关键词 affective behaviors cariprazine D3 neurons olfactory tubercle social behaviors
Does digital literacy promote climate disaster-adaptive production behaviors among grain-producing smallholders in China? 认领 引用 被引量：1
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作者 Qingyun Bai Jiajia Li +3 位作者 Jian Zhang Dungang Zang Kuan Zhang Qianling Shen 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2026年第6期2214-2228,共15页
Climate disasters lead to substantial economic losses and grain yield losses,emphasizing the need for adaptation to ensure food security.As digital technologies advance,it is imperative to investigate how digital lite... Climate disasters lead to substantial economic losses and grain yield losses,emphasizing the need for adaptation to ensure food security.As digital technologies advance,it is imperative to investigate how digital literacy among grain farmers affects their adaptive production behaviors in the face of climate disasters.Drawing on survey data from 505 grain-producing smallholders in Sichuan Province,China,this study constructs a theoretical framework linking digital literacy,climate disaster risk perception,and adaptive production behaviors.Empirical analysis shows that digital literacy positively impacts the adaptive production behaviors of grain-producing smallholders.Our results are robust across various models and tests.An analysis of the mediation mechanism reveals that digital literacy contributes to climate disaster-adaptive production behaviors by improving the awareness of climate disaster risks.Heterogeneity analysis shows that the positive impact of digital literacy is more pronounced for smallholders that receive internet skills training and climate information services,and this impact intensifies as the level of agricultural infrastructure improves.The findings suggest that digital literacy plays a key role in reducing production risks,thereby contributing to increased sustainable agricultural development among smallholders. 展开更多
关键词 digital literacy climate disaster-adaptive production behaviors grain-producing smallholders China
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Effect of grain size on fatigue behaviors of Mg-2.6Nd-0.35Zn-xZr alloys 认领 引用
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作者 Lun-yong Zhang Yan-ping Chen +5 位作者 Xian-xing Wang Hong-xian Shen Hong-hui Liu Fu-yang Cao Zhi-liang Ning Jian-fei Sun 《China Foundry》 SCIE EI CAS CSCD 2026年第2期186-196,共11页
High-performance magnesium alloys are in great demand to meet the lightweight design requirements of aircraft.Grain size has long been recognized as a key factor influencing the mechanical properties of alloys.This st... High-performance magnesium alloys are in great demand to meet the lightweight design requirements of aircraft.Grain size has long been recognized as a key factor influencing the mechanical properties of alloys.This study investigates the effect of grain size,controlled by Zr addition,on the fatigue behavior of a recently developed low-cost Mg-2.6Nd-0.35Zn alloy,through systematic characterization and analysis of stress-life(S-N)curves,fatigue crack propagation,fracture surface morphology,stress intensity factor,and crack propagation threshold.The results show that after heat treatment(solution at 525±5℃ for 8 h and water quenching at 60-80℃,followed by aging at 250±5℃for 14 h and then air cooling),coarse-grained specimens(average grain size approximately 596μm)containing 0.12wt.%Zr exhibit greater resistance to fatigue crack propagation than fine-grained specimens(average grain size approximately 94μm)containing 0.46wt.%Zr.Coarse grains promote intergranular fracture,while fine grains favor transgranular fracture.In addition,coarse grains reduce the sensitivity of the crack tip to stress concentration.Furthermore,fine-grained samples demonstrate a longer total fatigue life,owing to their superior resistance to crack initiation,which significantly prolongs the crack initiation stage.These findings highlight the importance of optimizing grain size to achieve the best possible fatigue resistance in Mg-Nd-Zn-Zr alloys for practical engineering applications. 展开更多
关键词 Mg-Nd-Zn-Zr alloys grain size fatigue behaviors crack propagation crack initiation
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Microstructural evolution and tensile deformation behaviors of fine-grained Fe40Mn20Co20Cr15Si5high entropy alloy prepared by friction stir processing 认领 引用
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作者 Jia LIN Yuan FANG +7 位作者 Wen WANG Peng HAN Ting ZHANG Qiang LIU Ya-ting XIANG Feng-ming QIANG Ke QIAO Kuai-she WANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2026年第3期842-854,共13页
A fine-grained metastable dual-phase Fe40Mn20Co20Cr15Si5high entropy alloy(CS-HEA)with excellent strength and ductility was successfully prepared by friction stir processing(FSP).The microstructural and... A fine-grained metastable dual-phase Fe40Mn20Co20Cr15Si5high entropy alloy(CS-HEA)with excellent strength and ductility was successfully prepared by friction stir processing(FSP).The microstructural and mechanical properties of the fine-grained CS-HEA were characterized.The results showed that as-cast shrinkage cavities and elemental segregation were eliminated.The average grain size was refined from 121.1 to 5.4μm.The face-centered cubic phase fraction increased from 23%to 82%.During tensile deformation,dislocation slip dominated at strains ranging from 5%to 17%,followed by transformation induced plasticity(TRIP)from 17%to 26%,and twin induced plasticity(TWIP)from 26%to 37%.The yield strength,ultimate tensile strength,and elongation of the fine-grained CS-HEA were 503 MPa,1120 MPa,and 37%,respectively.The strength-ductility synergy of fine-grained CS-HEA was attributed to the combined effects of TRIP,TWIP,dislocation strengthening,and fine-grained strengthening. 展开更多
关键词 friction stir processing metastable high entropy alloy fine-grained microstructure deformation behaviors transformation-induced plasticity
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Long-term real-world PM2.5 exposure induces depression-like behaviors in mice by disrupting nuclear factor erythroid 2-related factor 2-mediated astrocyte-to-microglia communication 认领 引用
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作者 Nannan Huang Weiqing Shi +4 位作者 Cuishuang Dong Bin Li Yaohan Wang Hanqing Chen Xiaobo Li 《Neural Regeneration Research》 SCIE CAS CSCD 2026年第7期3238-3248,共11页
Long-term exposure to ambient fine particulate matter(PM2.5)may increase the risk of neurotoxicity in human populations.However,research studies on the underlying mechanisms of chronic PM2.5-induced depression-like be... Long-term exposure to ambient fine particulate matter(PM2.5)may increase the risk of neurotoxicity in human populations.However,research studies on the underlying mechanisms of chronic PM2.5-induced depression-like behaviors,and potential therapeutical strategies,remain scarce.In the present study,after long-term exposure to real-world PM2.5 for 15 weeks,male mice displayed depression-like behaviors,which were revealed using the open field and sucrose preference tests.Mechanistically,chronic PM2.5 exposure promoted astrocytic A1 polarization and disrupted reduction-oxidation balance in the mouse hippocampus.Furthermore,PM2.5-exposed mice displayed pathological damage to hippocampal neurons as well as the inhibition of nuclear factor erythroid 2-related factor 2 signaling.Astrocytic ablation of nuclear factor erythroid 2-related factor 2 exacerbated PM2.5-induced hippocampal neuronal injury in mice via the disruption of astrocyte-to-microglia communication;this finding was confirmed in mice with bilateral and unilateral hippocampal astrocytic Nfe2l2 knockdown.Importantly,the upregulation of nuclear factor erythroid 2-related factor 2 activation by procyanidin significantly ameliorated PM2.5-induced depression-like behaviors through the remodeling of astrocyte-to-microglia communication.Together,our findings shed light on the important role of hippocampal astrocytic nuclear factor erythroid 2-related factor 2 activation for maintaining astrocyte-to-microglia communication,and indicate potential research avenues for therapeutic strategies against PM2.5-induced depresson-like behaviors. 展开更多
关键词 air pollution astrocyte-to-microglia communication depression-like behaviors fine particulate matter(PM2.5) neurotoxicity nuclear factor erythroid 2-related factor 2 oxidative stress procyanidins
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Effects of ultrasonic frequency pulse arc on corrosion behaviors of wire-arc directed energy-deposited Inconel 690 alloys 认领 引用
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作者 Yubin Zhou Yan Zhang +10 位作者 Zewu Qi Baoqiang Cong Qingfu Yang Lingwei Cai Li Lu Zhongbing Chen Zhenxin Liang Jianping Yang Jiankun Xiong Zhaoyang Yan Bojin Qi 《Additive Manufacturing Frontiers》 CAS CSCD 2026年第2期275-283,共9页
This study examined the impact of an ultrasonic frequency pulse(UFP)arc on the corrosion behavior of wire-arc directed energy-deposited(WADED)Inconel 690 alloys.The UFP-WADED Inconel 690 exhibited more random grain or... This study examined the impact of an ultrasonic frequency pulse(UFP)arc on the corrosion behavior of wire-arc directed energy-deposited(WADED)Inconel 690 alloys.The UFP-WADED Inconel 690 exhibited more random grain orientation,refined grains,and minor-sized carbide precipitates than the direct current(DC)sample.The introduction of the UFP arc improved electrochemical behavior,including the open circuit potential value and impedance loop,and reduced the corrosion current.The UFP component exhibited a wider passive range and higher pitting potential.Corrosion pitting occurred near the Al-enrichedγ'-phase and carbide precipitates owing to the microgalvanic corrosion in the DC and UFP samples.The larger carbide precipitates in the DC sample induced defects in the passive film.The UFP arc significantly reduced element segregation and led to minor pittings,which resulted in improved corrosion resistance. 展开更多
关键词 Ultrasonic frequency pulse arc Wire-arc directed energy deposition Inconel 690 alloy Microstructure Corrosion behaviors
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Achieving Excellent Strength-Ductility in Nb-Si Superalloys via Stable Bi-Phases Structure and Nano-Precipitation Behaviors 认领 引用
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作者 Xiao-Wei Wang Rui-Run Chen +4 位作者 Qi Wang Qi-Bin Wang Yu-Xin Wang Yan-Qing Su Heng-Zhi Fu 《Rare Metals》 SCIE EI CAS CSCD 2026年第2期295-306,共12页
Nb-Si-based superalloys are considered as the most potential candidate materials for nickel-based superalloys due to the lower density and higher using temperature.Here,a type of stable Nbss/γNb5Si3 bi-phases s... Nb-Si-based superalloys are considered as the most potential candidate materials for nickel-based superalloys due to the lower density and higher using temperature.Here,a type of stable Nbss/γNb5Si3 bi-phases structure with a coherent interface has been successfully designed.Additionally,the Nbss andγNb5Si3 phases showcase the orientation relationship of■.There are also some nano-γNb5Si3 phases in the Nbss matrix with a coherent relationship.The lower mixing enthalpies of Ti,Zr,Hf,and Si in Nbss phases accelerate the formation of nano-γNb5Si3,and the dislocations as crystal defects provide the heterogeneous nucleation sites for nano-γNb5Si3 phases.In addition,the room temperature fracture toughness has been improved to 15.03 MPa·m1/2,resulting from the intrinsic toughness of Nbss andγNb5Si3 phases being improved according to nanoindentation.Moreover,the nanoindentation experiment exhibits that the optimal values of microhardness and elastic modulus are 5.53 and 160.31 GPa for Nbss,and 13.88 and 218.26 GPa forγ(Nb,X)5Si3 phases,respectively.Under high temperature conditions,the phase boundaries of brittleγ(Nb,X)5Si3 are deformable at 1200°,which can accommodate more plasticity.In addition,the recrystallized behaviors are also found in our alloys,which can consume lots of dislocations to relieve the stress concentration. 展开更多
关键词 bi-phases structure dislocation behaviors mechanical properties nano-precipitation Nb-Si based superalloys
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Compliance with Three Movement Behaviors and Psychological Health among Adults with Diabetes 认领 引用
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作者 Wenjiao Li Shiliang Chen +2 位作者 Shihui Chen Xinxing Li Yanjie Zhang 《International Journal of Mental Health Promotion》 2026年第2期68-82,共15页
Objectives:24-h movement behaviors(24-HMB),encompassing physical activity,sedentary behavior,and sleep duration,are increasingly regarded as interrelated and important factors for mental health.However,evidence on the... Objectives:24-h movement behaviors(24-HMB),encompassing physical activity,sedentary behavior,and sleep duration,are increasingly regarded as interrelated and important factors for mental health.However,evidence on the comprehensive association of these behaviors with mental health in adults with diabetes in developing countries remains scarce.This study examined the association between 24-HMB guidelines and psychological health among adults with diabetes in developing countries.Methods:Data were retrieved from the World Health Organization’s study on Global Aging and Adult Health Survey dataset.Adults(N=1905)diagnosed with diabetes from five low-and middle-income countries were included.The exposure of interest was adherence to 24-HMB guidelines,depression,cognition,and quality of life(QoL).Multiple logistic and multiple linear regression analyses were used to examine the association between meeting 24-HMB guidelines and depression,cognition,and QoL,respectively.Results:This cross-sectional study revealed that 28.61%complied with all three 24-HMB guidelines.Diabetic patients who met more numbers of 24-HMB guidelines had lower depression risk(OR=0.74,95%CI:0.61 to 0.91,p=0.004),greater cognition(β=0.42,95%CI:0.25 to 0.60,p<0.001),and QoL(β=1.30,95%CI:1.04 to 1.55,p<0.001)with the non-compliant population.For specific combinations,meeting all three guidelines were significantly associated with lower odds of depression,improved cognitive function,and enhanced QoL(all p<0.001).Conclusion:These findings support that meeting 24-HMB guidelines in a single or combined movement behaviors was significantly related to reduced risk of depression,enhanced cognitive function,and improved QoL among individuals with diabetes. 展开更多
关键词 Movement behaviors diabetes mellitus mental health quality of life sleep
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Reducing Depression and Anxiety in Children and Adolescents Facing Food Insecurity:The Joint and Independent Contributions of Movement Behaviors 认领 引用
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作者 Wenjiao Li Shiliang Chen +1 位作者 Xinxing Li Yanjie Zhang 《International Journal of Mental Health Promotion》 2026年第7期108-120,共13页
Backgrounds:Youth living in food-insecure households show greater vulnerability to psychiatric symptoms,including anxiety and depression.Although physical activity and sedentary behavior are established correlates of ... Backgrounds:Youth living in food-insecure households show greater vulnerability to psychiatric symptoms,including anxiety and depression.Although physical activity and sedentary behavior are established correlates of youth mental health,their associations within the context of food insecurity households remain understudied.This study examines how physical activity and sedentary behavior relate to depression and anxiety risk among children residing in food-insecure households.Methods:We analyzed data from the 2021–2022 National Survey of Children’s Health(NSCH),focusing on youth aged 6–17 years(n=2118)living in food insecurity households.Multivariate logistic regression models adjusted for age,sex,race,parental education,family income,and overweight status were used to estimate odds ratios(ORs)and 95%confidence intervals(CIs)for the link between physical activity and sedentary time and the risks of depression and anxiety.Results:Meeting physical activity guideline(≥60 min MVPA/day)was significantly associated with lower odds of both depression(OR=0.63,95%CI:0.44–0.89,p=0.009)and anxiety(OR=0.60,95%CI:0.45–0.78,p<0.001).Meeting sedentary behavior guideline showed a significant association with reduced odds of depression(OR=0.56,95%CI:0.43–0.74,p<0.001)and anxiety(OR=0.78,95%CI:0.64–0.97,p=0.025).Most notably,children who met both physical activity and sedentary behavior guidelines exhibited a significant reduction in depression(OR=0.56,95%CI:0.33–0.94,p=0.027)and anxiety(OR=0.61,95%CI:0.43–0.87,p=0.009)risk.Conclusions:The findings of this study reveal associations between meeting physical activity and sedentary behavior guidelines independently and jointly reduced risks of depression and anxiety,respectively.Future longitudinal cohort study should examine the prospective association of physical activity,sedentary behavior,and mental health among youth living in food-insecure households. 展开更多
关键词 Movement behaviors mental disorders food insecurity National Survey of Children’s Health(NSCH)
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Dynamic Behaviors of Localized Waves of the(2+1)-Dimensional Yu-Toda-Sasa-Fukuyama Equation 认领 引用
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作者 SUN Xiaoqing XIA Yarong +1 位作者 YAO Ruoxia WANG Weiqing 《应用数学》 北大核心 2026年第2期624-638,共15页
In this article,by employing the Hirota bilinear approach and the long wave limit method,we not only derive soliton solutions,lump solutions,and hybrid solutions for the(2+1)-dimensional Yu-Toda-Sasa-Fukuyama(YTSF)equ... In this article,by employing the Hirota bilinear approach and the long wave limit method,we not only derive soliton solutions,lump solutions,and hybrid solutions for the(2+1)-dimensional Yu-Toda-Sasa-Fukuyama(YTSF)equation,but also analyze the dynamical behaviors of nonlinear local wave propagation in shallow water.Firstly,based on the Hirota bilinear approach,one to four-order soliton solutions of the YTSF equation are obtained,and the effects of different parameters on the amplitude,propagation trajectory,and displacement of solitons are investigated.Secondly,using the long wave limit approach,one to three-order lump solutions and various physical quantities of the YTSF equation are derived.It is found that the real and imaginary parts of the parameter pi dominate the propagation trajectory and the shape of lump waves,respectively.Furthermore,we construct the hybrid solution for the YTSF equation,leading to the conclusion that the interaction between lumps and solitons constitutes an elastic collision.To intuitively understand the dynamic behaviors of these solutions,we conduct numerical simulations to present vivid three-dimensional visualizations. 展开更多
关键词 (2+1)-dimensional Yu-Toda-Sasa-Fukuyama equation Hirota bilinear approach Lump solutions Dynamic behaviors
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Levels and Disparities of 24-hour Movement Behaviors of Chinese Children Aged 3-5 Years:A Nationally Representative Cross-sectional Study(2019-2021) 认领 引用
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作者 Yifan Duan Ji Zhang +7 位作者 Linxiao Guo Xuehong Pang Qian Zhang Yuying Wang Tao Xu Bowen Chen Zhenyu Yang Wenhua Zhao 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2026年第3期285-296,共12页
Objective This study aimed to describe 24-hour movement behaviors,including physical activity,sedentary behavior,and sleep period,among Chinese preschoolers using nationally representative data,and examine disparities... Objective This study aimed to describe 24-hour movement behaviors,including physical activity,sedentary behavior,and sleep period,among Chinese preschoolers using nationally representative data,and examine disparities by age,gender,and residence.Methods A cross-sectional analysis was conducted using data from the China National Nutrition and Health Systematic Survey for Children(2019–2021),including 10,935 children aged 3–5 years.Daily total time of physical activity(TPA),total time of sedentary behaviors(TSB),and total sleep period(TSP)was collected via validated structured questionnaires.Physical inactivity was defined as<180 minutes of TPA per day.Results Median TPA was 121.4(IQR:71.4−209.6)minutes/day,and TSB was 231.4(IQR:175.0−304.3)minutes/day,with 11.46±1.00 hours/day average TSP.Overall,68.8%were physically inactive,with higher prevalence in rural(73.3%)versus urban areas(64.8%,P<0.001).TPA and TSB increased with age,while TSP decreased(all P<0.001).No significant gender differences were observed.Conclusion Most Chinese preschoolers exhibit insufficient physical activity and excessive sedentary behaviors,with notable urban–rural disparities and an escalating trend of ageing.Continuous monitoring and targeted interventions,especially in rural areas,are urgently needed. 展开更多
关键词 Physical activity Sedentary behavior Sleep duration Preschool children Urban-rural disparity Physical inactivity
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Effect of annealing treatment on microstructure,mechanical properties and biodegradable behaviors of high-performance wrought Zn−0.1Mg alloy 认领 引用
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作者 Huan LIU Li-feng YE +7 位作者 Jing-bo LI Chao SUN Yu-na WU Jia JU Hang TENG Jing-hua JIANG Jing BAI Feng XUE 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2026年第2期451-469,共19页
To investigate the aging mechanisms and elucidate the correlations between unstable microstructure and performance in biodegradable Zn alloys,the accelerated aging experiment was conducted on a high-performance wrough... To investigate the aging mechanisms and elucidate the correlations between unstable microstructure and performance in biodegradable Zn alloys,the accelerated aging experiment was conducted on a high-performance wrought Zn−0.1Mg alloy by annealing at 200℃ for varying durations.The findings reveal that the tensile strength of the alloy rapidly and significantly declines with prolonged annealing time,decreasing from 383 MPa for the as-received alloy to 102 MPa for the alloy subjected to 1440 min of annealing.The primary factors contributing to this considerable reduction in strength are static recrystallization,grain coarsening,and dislocation annihilation.Initially,the ductility of the alloy shows fluctuations,ultimately experiencing a marked decrease after extended annealing.This decline is linked to the grain growth and heightened texture intensity,while the unusual increase in ductility observed between 30 and 120 min of annealing is likely due to the formation of twins.In addition,due to rapid grain growth and an increase in precipitates and twins,the corrosion resistance of the alloy in Hank’s solution has worsened,with the corrosion rate rising from 0.037 to 0.069 mm/a following 300 min of annealing. 展开更多
关键词 Zn−0.1Mg alloy annealing microstructure evolution mechanical properties corrosion behavior
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Volume change and creep behaviors related to stress-phase transition path in methane hydrate-bearing silty sand 认领 引用
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作者 Jiazuo Zhou Qi Fan +1 位作者 Zhenyu Zhu Changfu Wei 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第2期1526-1540,共15页
The volume change behavior of natural gas hydrate-bearing sediment is essential as it influences settlement,strength,and stiffness,which directly affect the stability of hydrate reservoirs during hydrate extraction or... The volume change behavior of natural gas hydrate-bearing sediment is essential as it influences settlement,strength,and stiffness,which directly affect the stability of hydrate reservoirs during hydrate extraction or in response to environmental changes.The volume change is influenced not only by stress but also by the formation and dissociation of hydrates.This study adopted a customized apparatus for one-dimensional compression tests,allowing independent control of gas pressure and effective stress.Tests were conducted on samples with different hydrate saturations along various temperature-gas pressure-effective stress paths,yielding some conclusions related to compressibility and creep.An unusual phenomenon was observed under low-stress conditions:hydrate formation led to shrinkage rather than expansion.Three potential mechanisms behind this occurrence were discussed.As hydrate saturation increases,the yield stress rises while the compression and swelling indexes remain minimally affected.After hydrate dissociation,the compression curve of hydrate-bearing sediment drops to that of hydrate-free sediment.Once hydrate is formed,the compression curve of hydrate-free sediment gradually approaches that of hydrate-bearing sediment during the subsequent loading.Under low-stress conditions,the creep of both hydrate-free and hydrate-bearing sediments is very weak.However,when stress increases,significantly beyond the yield stress,the creep of both sediments increases significantly,with hydrate-bearing sediment exhibiting much greater creep than hydrate-free sediment. 展开更多
关键词 Hydrate-bearing sediment Phase transition Volume change Creep behavior
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Impact of physical heterogeneity on hydro-mechanical behaviors in full-scale buffer blocks for HLRW repositories 认领 引用
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作者 Wen-Jie Dai Jing-Li Xie +1 位作者 Sheng-Fei Cao Yong-Gui Chen 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第5期3991-4006,共16页
Compacted bentonite blocks are proposed for buffer barriers in deep geological repositories for high-level radioactive waste(HLRW)disposal.These blocks,manufactured through uniaxial compression in molds,exhibit hetero... Compacted bentonite blocks are proposed for buffer barriers in deep geological repositories for high-level radioactive waste(HLRW)disposal.These blocks,manufactured through uniaxial compression in molds,exhibit heterogeneity that may impact long-term buffer performance.This study focuses on the physical and hydro-mechanical heterogeneity of full-scale blocks induced by the compaction process.Sector-shaped blocks,with radii of 600 mm and 1200 mm and a height of 200 mm,were axially compressed.Key parameters,including water content,dry density,elasticity modulus,swelling pressure,and permeability,were measured to assess the heterogeneity.Results show that the heterogeneity in the upper layer is primarily caused by differences in drainage and gas expulsion pathways.As depth increases,water content and dry density become more correlated.Hydro-mechanical behavior is largely controlled by dry density,but its fluctuation ratio is much higher than that of dry density.Regarding the microstructure,pore structure heterogeneity follows the order:corner regions>edge regions>center regions,and upper layer>middle layer>lower layer.Vertical microcracks also develop to varying degrees,increasing the anisotropy of the blocks.Upon these observations,the study thoroughly discusses the feasibility and challenges of reckoning the hydro-mechanical properties of blocks using dry density distribution alongside laboratory-scale data.Additionally,it proposes an indicator to evaluate the overall heterogeneity of buffer blocks.These findings highlight the inherent heterogeneity of compacted bentonite blocks at the engineering scale,providing valuable insights for future experiments and simulations. 展开更多
关键词 Full-scale buffer block Inherent heterogeneity Physical property Hydro-mechanical behavior
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Analysis of cracking behaviors of five clayey materials using 3D point cloud data 认领 引用
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作者 Xin Wei Pengsen Wang +1 位作者 Yao Gao Ling Xu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第7期5731-5743,共13页
In recent years,drought-induced soil cracking has become increasingly prevalent,posing significant challenges to geotechnical engineering applications due to the associated hazards.Previous studies have investigated s... In recent years,drought-induced soil cracking has become increasingly prevalent,posing significant challenges to geotechnical engineering applications due to the associated hazards.Previous studies have investigated soil cracking behaviors and mechanisms via multi-scale methods.However,research on the spatial distribution characteristics of soil cracks and their depth evolution mechanisms is still rare.This paper analyzes the three-dimensional(3D)deformation of fiveclayey materials.In this study,3D surface elevation data of soil samples were acquired using a Gocator 3110 structured-light sensor.The reconstruction process involved point cloud acquisition and rasterization,Delaunay triangulation meshing,and calculation of crack depth.Different cracking behaviors are investigated,such as cracking in opening mode and shearing mode,coalescence and bifurcation of cracks,etc.The mineralogical analysis is carried out to reveal different cracking behaviors of clays.It is concluded that the crack depth of montmorillonite is larger than that of kaolin,reflectingits strong shrinkage characteristic,which makes the crack evolve deeper than the other materials.This technique enables multi-dimensional observation of soil crack propagation.The mineralogical analysis is carried out to reveal the different cracking behaviors of clays.It is concluded that microstructure and mineralogy are key factors influencingcracking behavior.Understanding soil cracking behaviors is significantfor engineering protection,geohazard prevention,and geological monitoring. 展开更多
关键词 Clay Free desiccation Laser scanning technique Three-dimensional(3D)point cloud data Cracking behavior
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Screen time in preschool-aged children and attention deficit hyperactivity disorder-related behaviors:A literature review 认领 引用
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作者 Tungki Pratama Umar Aulia Wiratama Putra +2 位作者 Devin Mahendika Maureen Miracle Stella Kevin Tandarto 《World Journal of Clinical Pediatrics》 2026年第1期46-53,共8页
In this digital era,excessive screen usage has been reported to worsen the symptoms of attention deficit hyperactivity disorder(ADHD)in children.However,this connection is found to be bidirectional,with both phenomena... In this digital era,excessive screen usage has been reported to worsen the symptoms of attention deficit hyperactivity disorder(ADHD)in children.However,this connection is found to be bidirectional,with both phenomena impacting each other.The current literature review will summarize some research findings on the correlation between screen time and ADHD-related behaviors.Studies have found that the inattentional and hyperactive/impulsive behaviors of ADHD are positively correlated with screen time.One study showed statistically significant longitudinal correlations between screen time at age three and inattention behaviors and hyperactivity/impulsivity behaviors at age four,but no concurrent association between screen time and either of these behaviors or scores at age three.Crucially,screen usage beyond the two-hours mark was linked to a higher risk of externalizing morbidity that is clinically significant,particularly inattention issues.Meanwhile,screen usage can exacerbate the symptoms of ADHD in children,including aggression,negative emotions,and pressure from life events,according to a summary of pertinent studies. 展开更多
关键词 Attention deficit hyperactivity disorder Behavioral problem Inattention Impulsivity Pediatric Screen time
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Numerical study on phase difference-driven mechanical behaviors of gravel–structure interface under three-dimensional circular cyclic shear 认领 引用
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作者 Zhenhai WANG Yuke WANG 《ENGINEERING Structure and Civil Engineering》 SCIE EI CAS CSCD 2026年第2期420-439,共20页
Soil-structural interfaces,such as those between foundations,tunnels,retaining walls,and slopes,serve as critical zones for stress and deformation transfer in geotechnical systems.Although extensive research exists on... Soil-structural interfaces,such as those between foundations,tunnels,retaining walls,and slopes,serve as critical zones for stress and deformation transfer in geotechnical systems.Although extensive research exists on two-dimensional interface mechanics,the zonal characteristics,non-coaxial behavior,and reversible volumetric deformation mechanisms under three-dimensional(3D)loading remain poorly understood.To address this gap,a series of discrete element method(DEM)simulations focused on the phase-dependent response of shear stress,normal displacement,and microstructural interactions were conducted in this study.The influence of the tangential displacement phase difference Dpon the 3D cyclic shear behavior of gravel-structure interfaces under circular shear paths was investigated based on DEM.The controlling role of shear path geometry in governing non-coaxial behavior and reversible volumetric deformation is explicitly revealed.Specifically,it is demonstrated that stable,hysteretic stress-displacement loops with minimal volumetric hysteresis are promoted by circular shear paths(Dp=π/2,3π/2),whereas abrupt stress reversals and amplified dilatancy-recompression cycles are induced by bidirectional linear paths(Dp=π,2π).Furthermore,periodic oscillations of non-coaxial angles(α3)are observed,transitioning from 90°under pure rotation to peak fluctuations exceeding 30°under phase-shifted shear.These mechanistic understandings are highlighted as being crucial for the advancement of 3D interface constitutive models. 展开更多
关键词 gravel-structure interface cyclic shear non-coaxial behavior reversible volumetric deformation phase difference microscopic responses
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Anxiety-like behaviors increased in juvenile rats in the streptozotocin-induced diabetes model during the early stage 认领 引用
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作者 Özlem Ozcanlı Cay Hasan Calışkan 《World Journal of Psychiatry》 SCIE 2026年第7期444-453,共10页
BACKGROUND Diabetes is an endocrinopathy characterized by the inability to produce insulin or insufficient insulin production because of the destruction of beta cells in the pancreas caused by autoimmune or other epid... BACKGROUND Diabetes is an endocrinopathy characterized by the inability to produce insulin or insufficient insulin production because of the destruction of beta cells in the pancreas caused by autoimmune or other epidemiological factors.Diabetes can lead to physical and psychological complications.AIM To investigate early behavioral changes in an experimental diabetes model in juvenile rats.METHODS In this study,a total of 14 juvenile male Wistar rats(7 rats per group)were used.To induce the diabetes model,120 mg/kg streptozotocin(STZ)was administered,while the control group received 1 mL/kg physiological saline.The open field test and the hole-board test were performed for five minutes each.Unpaired comparisons were evaluated using Student’s t test or the Mann-Whitney U test.Correlations were analyzed using the Pearson test.RESULTS Severe hyperglycemia was observed in rats in the diabetes mellitus model induced by STZ,and all diabetic rats displayed glucose levels above 400 mg/dL.In the open-field test,the time spent in the central area,the number of rearings,and the total distance traveled were significantly lower in diabetic rats than in naive rats(P<0.05).In the hole-board test,the duration and frequency of total head dipping were considerably lower in diabetic rats than in healthy rats(P<0.01).The grooming time(P<0.01)and freezing time(P<0.0001)increased dramatically in the diabetes mellitus group.A remarkable correlation was found between behavioral changes and hyperglycemia.CONCLUSION Our data indicate that early-stage diabetes induced by STZ increases anxiety-like behaviors and impairs exploratory behaviors.These behavioral changes may also occur in children with undiagnosed or untreated hyperglycemia and can provide important clues in clinical practice. 展开更多
关键词 Anxiety-like behaviors Diabetes mellitus Early-stage changes Hole-board test Juvenile rats Open field test Streptozotocin
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Parental career-related behaviors and adolescents’career adaptation:Evidence from college students in transition from school to work 认领 引用
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作者 Fengjin Zhou Zhen Wei 《Journal of Psychology in Africa》 2026年第3期405-415,共11页
This study examined parental career-related behaviors and adolescents’career adaptation and the role of personal growth initiative and future work self salience in that relationship.Survey data were from 794 college ... This study examined parental career-related behaviors and adolescents’career adaptation and the role of personal growth initiative and future work self salience in that relationship.Survey data were from 794 college students(female ratio=46.85%;age=21.22±0.75),attending three universities in Central China.Results following structural equation modeling show that higher parental career-related behavior is associated with higher adolescents’career adaptation.However,parental interference and lack of engagement are associated with lower adolescents’career adaptation.Moreover,parental supportive behaviors are associated with adolescents’career adaptation through adolescents’personal growth initiative and future work self-salience.Conversely,parental interference and lack of engagement are associated with lower adolescents’personal growth initiative and future work self salience.The findings align with Career Construction Theory and highlight that student counseling and development services should emphasize the importance of considering the family environment in adolescents’career development. 展开更多
关键词 parental career-related behaviors career adaptability personal growth initiative future work self salience
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