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Generation of a high-power,broadband supercontinuum spanning from visible to mid-infrared via incoherent beam combination in a GeO2-core fiber bundle 认领 引用
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作者 Kai Xia Ruipeng Hou +11 位作者 Xuzhao Zhang Chonghao Huang Lele Yu Biaoqi Wen Chao Chen Zhilin Zhang Zhicheng Zhang Chao Mei Xing Luo Peilong Yang Shixun Dai Qiuhua Nie 《High Power Laser Science and Engineering》 SCIE EI CAS CSCD 2026年第2期20-27,共8页
In this work,we experimentally demonstrate a high-power supercontinuum(SC)that covers from visible to mid-infrared(MIR)in a GeO2-core fiber(GCF)bundle via incoherent beam combination.In the experiment,the SC generatio... In this work,we experimentally demonstrate a high-power supercontinuum(SC)that covers from visible to mid-infrared(MIR)in a GeO2-core fiber(GCF)bundle via incoherent beam combination.In the experiment,the SC generation in a single GCF was initially explored,and an SC spanning from visible to MIR regions was obtained,with average power of less than 10 W.To increase the output power,we fabricated a 3×1 high-power GCF-based tapered fiber bundle,incoherently combining three channels of the previously mentioned replicas.This yielded a broadband SC spectrum with a maximum average power of 23.1 W and a spectral bandwidth covering 0.73–3.1μm.The obtained spectrum power fluctuation was measured over 1 hour,showing a root mean square value of 0.7%.To the best of our knowledge,this represents the highest power SC from visible to MIR regions obtained in GCFs pumped by 1.55μm high-power pulses. 展开更多
关键词 all-fiber laser beam combination GeO2-core fiber supercontinuum generation tapered fiber bundle
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Genesis of lamina combinations and intelligent well-logging interpretation in the upper Xiaganchaigou Formation,Yingxi area,Qaidam Basin,China 认领 引用
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作者 Jia-Lin Fu Da-Li Yue +6 位作者 Wu-Rong Wang Kun-Yu Wu Han Wang Ying-Hai Jiang Shu-Qi Zhang Zi-Mo Xu Wei Li 《Petroleum Science》 SCIE EI CAS CSCD 2026年第6期3091-3109,共19页
The laminar sedimentary structures of saline lacustrine mixed rocks affect both organic matter enrichment and reservoir storage performance.However,due to the small-scale nature of laminae,large-scale identification u... The laminar sedimentary structures of saline lacustrine mixed rocks affect both organic matter enrichment and reservoir storage performance.However,due to the small-scale nature of laminae,large-scale identification using well-logging data during reservoir exploration and development remains challenging.It is necessary to introduce a research method to identify and characterize the development of different types of laminae.Based on analyses of typical cores,XRD data,and welllogging curves from the upper member of the Xiaganchaigou Formation in the Yingxi area,five main types of laminae and six lamina combinations were classified.A Transformer-based intelligent recognition method was then applied to identify these lamina combinations from well-log data,with the Random Forest algorithm used as a comparative benchmark.Verification results show that the Transformer model achieves a higher total accuracy of 84%in lamina combination recognition.This study proposes a new approach for the conventional well-log characterization of laminae,in which the classification is established from the perspective of laminae genesis.It reflects the development patterns of lamina combinations driven by paleoenvironmental changes,and selects an appropriate intelligent recognition method to address the challenges in well-log characterization of such reservoirs.In terms of engineering applications,this study can accurately indicate the positions of high-quality reservoirs within sedimentary cycles during field development.It provides a sedimentary facies-controlled basis for the three-dimensional characterization of reservoir quality,thereby offering a valuable reference for the exploration and development of reservoirs formed under similar sedimentary conditions. 展开更多
关键词 Lamina combination identification Transformer intelligent recognition Sedimentary origin E32 segment Qaidam Basin
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Quantifying and predicting trait combinations to enhance ecological multifunctionality of urban broad-leaf forest tree species:leaf carbon content is an essential trait 认领 引用
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作者 Ruiting Wang Sheng Xu +3 位作者 Kexin Gao Yixin Zhang Yan Li Xingyuan He 《Journal of Forestry Research》 SCIE EI CAS CSCD 2026年第1期98-110,共13页
Urban forests are highly multifunctional and provide numerous ecological functions.Plant functional traits individually or jointly influence the ecological multifunctionality of tree species(TS-EMF)and can also modify... Urban forests are highly multifunctional and provide numerous ecological functions.Plant functional traits individually or jointly influence the ecological multifunctionality of tree species(TS-EMF)and can also modify TSEMF in response to environmental changes.However,there has been limited exploration of multitrait combinations for predicting TS-EMF across seasons and of trait thresholds that enhance TS-EMF.Here,for 10 dominant tree species in urban forests of Northeast China,14 traits were measured and four aboveground and three belowground ecological functions assessed in three seasons.Ecological functions and TS-EMF differed significantly throughout the seasons(P<0.05).Synergistic relationships were found between carbon sequestration and oxygen release,between cooling and humidification,and between organic carbon accumulation and nutrient cycling.Notably,aboveground multifunctionality played a leading role in TS-EMF.With seasonal changes,resource allocation shifted toward traits related to resource acquisition rather than conservation to maintain TS-EMF.The combination of traits that predicted TS-EMF varied by type,accounting for up to 66.45%of the variation.TS-EMF was primarily driven by leaf structure in spring and by nutrient accumulation in autumn.Leaf carbon content(LCC)consistently served as a stabilizing factor for predicting TS-EMF across seasons.At 36.5-36.8 mg g-1,LCC had its optimal effect on TS-EMF.Other traits in combination that positively influence total TS-EMF include leaf nitrogen content(3.43-3.45 mg g-1),leaf phosphorus content(0.80-0.83 mg g-1),and leaf area(65.86-68.43 cm2).Within these specified trait thresholds,Morus alba and Quercus mongolica were identified as key species.These findings suggest that the trade-off between various ecological functions can be managed by altering plant traits across seasons.This approach could provide a theoretical foundation for enhancing the TS-EMF of urban forests through trait-based management,offering practical guidance for selecting tree species. 展开更多
关键词 Ecological multifunctionality of tree species Traits combination Urban forests Leaf carbon content
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Experimental Investigation on the Hydrodynamic Forces of the Multi-Net Trash Barrier System Under Wave-Current Combinations 认领 引用
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作者 SUN Yun-jia DING Guang-jia +2 位作者 LYU Ying-xue SONG Yue JI Xing-yu 《China Ocean Engineering》 SCIE EI CSCD 2026年第1期207-218,共12页
This study proposes a multi-net trash barrier system to ensure water intake safety in nuclear power plants,comprising various planar nets and net bags supported by piles and anchor blocks.A comprehensive physical mode... This study proposes a multi-net trash barrier system to ensure water intake safety in nuclear power plants,comprising various planar nets and net bags supported by piles and anchor blocks.A comprehensive physical model experiment was conducted in a three-dimensional wave basin to investigate the mooring forces on this barrier.The research analyzes the effect of blockage levels on the dynamic responses of pile-supported and floating nets within blockage ratios of 10%−70%under current-only,wave-only,and wave-current conditions.For optimal net span design,the study examines curvatures ranging from 0.2%to 18.6%,representing the extension proportion of arc length compared to straight-line distance in a span.Results indicate that combined water intake and wave action effects generate substantial forces on the net barrier,requiring careful consideration during design.Higher blockage ratios and lower curvatures correspond to increased net barrier tensions.For practical engineering applications,the recommended curvature for floating net barriers ranges from 7%to 10%for optimal net arc length design. 展开更多
关键词 multi-net trash barrier system blockage level curvature current-wave combination physical model tests
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The combination of Astragali Radix and Anemarrhenae Rhizoma in the treatment of ultraviolet skin damage by regulating the PI3K-AKT pathway 认领 引用
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作者 Jin-Sui He Jia-Yan Lin +6 位作者 Ding-Kang Sun Yi-Fan Zhao Pan Yang Li-Sha Ma Chun-Yan Diao Xue-Ying Liu Qing-Wei Wang 《Traditional Medicine Research》 2026年第3期1-11,共11页
Background:Human skin is affected by ultraviolet rays on a daily basis,and excessive ultraviolet radiation(UVR)can lead to sunburn erythema,tanning,photoaging,and skin tumors.The combination of Astragali Radix(AR)and ... Background:Human skin is affected by ultraviolet rays on a daily basis,and excessive ultraviolet radiation(UVR)can lead to sunburn erythema,tanning,photoaging,and skin tumors.The combination of Astragali Radix(AR)and Anemarrhenae Rhizoma(AAR)is a common pairing in traditional Chinese medicine(TCM).According to earlier studies,they possess properties capable of alleviating the adverse impacts of UVR on the skin.However,the specific actions and underlying mechanisms require further investigation.The study aims to analyze the efficacy of AR-AAR in preventing UVR-induced skin damage and to clarify the associated molecular mechanisms.Methods:Potential signaling pathways by which AR and AAR may protect against UVR-induced skin damage were identified with network pharmacology,molecular docking techniques and molecular dynamics(MD)simulation.Except the normal group,the back skin of SD rats was exposed to 1.1 mW/cm2 UVA combined with 0.1 mW/cm2 UVB daily,and the UVR skin damage model was established.Morphological features of skin tissues of different groups were discovered through Hematoxylin and Eosin(HE)staining,Masson staining,Weigert staining.ELISA was utilized to measure the levels of reactive oxygen species(ROS),Interleukin 6(IL-6),Interleukin 1β(IL-1β)and Tumor necrosis factos-α(TNF-α)in skin tissues.RT-PCR and Western blot were employed to quantify the mRNA and protein contents of PI3K,AKT,and MMP-9.Results:Network pharmacology analysis predicts that AR-AAR may improve skin damage induced by UVR through the PI3K/AKT signaling pathway.Histological staining shows that AR-AAR can significantly reduce inflammatory infiltration and fibrosis in damaged skin.Treatment with AR-AAR(2:1)significantly reduced the expression levels of IL-1β,IL-6,TNF-αand ROS in UVR-damaged rat skin.After treatment with AR-AAR(2:1),not only did the relative mRNA expression levels of PI3K and AKT and the protein expression levels of PI3K,AKT,P-PI3K,and P-AKT increase,but the mRNA and protein expression levels of MMP-9 decreased.Conclusion:The study indicate that the AR-AAR combination and its active components may mitigate UVR skin damage by modulating the PI3K/AKT signaling pathway. 展开更多
关键词 Astragali Radix Anemarrhenae Rhizoma combination ultraviolet skin damage
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Cryoablation remodels the immune microenvironment in hepatocellular carcinoma:From mechanistic insights to clinical translation in combination immunotherapy 认领 引用
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作者 Jia-Ju Xu Chun-Xiao Ni +2 位作者 Li-Dong Qin Ping Wang Jia-Ju Xu 《World Journal of Gastrointestinal Oncology》 SCIE 2026年第6期61-84,共24页
Hepatocellular carcinoma remains a persistent therapeutic challenge,in part due to an immunosuppressive tumor microenvironment that renders it a“cold”tumor and limits the efficacy of immune checkpoint inhibitors.Loc... Hepatocellular carcinoma remains a persistent therapeutic challenge,in part due to an immunosuppressive tumor microenvironment that renders it a“cold”tumor and limits the efficacy of immune checkpoint inhibitors.Local cryoablation transcends its direct cytotoxic role by eliciting systemic immuno-modulatory effects.This review discussed the dual role of cryoablation in repro-gramming the hepatocellular carcinoma tumor microenvironment.Mechanisti-cally:Cryoablation induces immunogenic cell death,which serves as an in situ vaccine to release tumor antigens and danger signals to activate dendritic cells and prime tumor-specific T-cell responses.Nonetheless,this immunogenic res-ponse is normally offset by an attendant,transient immunosuppressive backlash.We review the preclinical and clinical data on the combination of cryoablation and immune checkpoint inhibitors,and a strategy that is aimed at blocking this inhibitory feedback and synergistically transforming the so-called“cold”tumors into immunologically“hot”tumors.The completeness of ablation,technical parameters and the host immune status are key determinants of therapeutic outcome.Current translational issues,especially with regard to stratification of patients,are discussed.Future progress of this promising combinatorial strategy will depend on the development of predictive biomarkers and on fine-tuning of combination regimens. 展开更多
关键词 Hepatocellular carcinoma Cryoablation Tumor microenvironment Immunotherapy Immunogenic cell death Combination therapy
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Case Report:A Case of Neuroendocrine Carcinoma of the Endometrium with Deficient DNA Mismatch Repair Had Achieved Clinical Complete Response after Combination Therapy 认领 引用
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作者 Xie Ding Xinfeng Liu +2 位作者 Cheng Dai Xiaoxiao Wang Zhaopeng Zheng 《Oncology Research》 SCIE 2026年第5期846-858,共13页
Background:Immunotherapy has markedly reshaped the therapeutic landscape for patients with postoperative progression and metastasis.As a programmed death-1(PD-1)inhibitor,camrelizumab has been proven to exhibit both e... Background:Immunotherapy has markedly reshaped the therapeutic landscape for patients with postoperative progression and metastasis.As a programmed death-1(PD-1)inhibitor,camrelizumab has been proven to exhibit both efficacy and safety in the treatment of advanced dMMR solid tumors.Case Description:A 58-year-old female patient with neuroendocrine carcinoma of the endometrium(NECE)who was treated with camrelizumab coupled with chemotherapy,subsequent maintenance monotherapy with camrelizumab,and adjuvant pelvic local radiotherapy.Up to December 2024,the patient has survived 28 months since treatment,with 26 months free from disease progression,and the assessment indicated a status of clinical complete response(cCR).Conclusion:The combined regimen achieves notable efficacy and is free of unexpected adverse effects,with only a radiotherapy-related pelvic insufficiency fracture(PIF)report. 展开更多
关键词 Neuroendocrine carcinoma of the endometrium(NECE) DNA mismatch repair deficiency(dMMR) programmed death-1(PD-1)inhibitor camrelizumab combination chemotherapy adjuvant radiotherapy case report
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Combination solution method based on the analogy of the generalized-αmethod for rigid-flexible coupling structural dynamics 认领 引用
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作者 Haoxiang Wang Huimin Zhang Yufeng Xing 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第7期424-443,共20页
In this paper,a combination solution method based on the analogy of the generalized-α(AG-α)method is proposed to solve linear rigid-flexible coupling structural dynamic problems,which is termed the G-G(ρ1∞,ρ_(... In this paper,a combination solution method based on the analogy of the generalized-α(AG-α)method is proposed to solve linear rigid-flexible coupling structural dynamic problems,which is termed the G-G(ρ1∞,ρ2∞)combination solution method.In the G-G(ρ1∞,ρ2∞)method,the degrees of freedom of the system are divided into two groups.One group with larger stiffness is solved by using the AG-αmethod with parameters determined by the spectral radiusρ1∞corresponding to the infinite frequency.The other,with smaller stiffness,is solved by using the AG-αmethod with parameters determined byρ2∞.Taking two differential equations of second order as test equations,the amplification matrix of the G-G(ρ1∞,ρ2∞)method has two pairs of principal eigenvalues and two spurious eigenvalues.The percentage amplitude decay and period elongation are defined and investigated with the two algorithmic frequencies and two algorithmic damping ratios.In addition,the accuracy order and stability of the combination method are discussed.Numerical examples show that the G-G(ρ1∞,ρ2∞)method can filter out the high-frequency modes and simultaneously keep the low-frequency modes when solving rigid-flexible coupling structural dynamic problems,and its numerical performances are superior to the AG-αmethod. 展开更多
关键词 Combination solution method Time integration method Rigid-flexible coupling Accuracy order
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Explainable electroencephalography-based attentiondeficit/hyperactivity disorder detection model with a combination of ternary pattern and twin wavelet transform 认领 引用
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作者 Yavuz Atas Serkan Kırık +9 位作者 Kübra Yıldırım Burak Tasci Prabal Datta Barua Ferhat Balgetir Sengul Dogan Turker Tuncer Ru-San Tan Elizabeth Palmer Aruna Devi U Rajendra Acharya 《World Journal of Psychiatry》 SCIE 2026年第3期141-158,共18页
BACKGROUND Attention-deficit/hyperactivity disorder(ADHD)is a common neurodevelopmental condition characterized by inattention,impulsivity,and hyperactivity.Traditional diagnosis relies on clinical evaluation,which is... BACKGROUND Attention-deficit/hyperactivity disorder(ADHD)is a common neurodevelopmental condition characterized by inattention,impulsivity,and hyperactivity.Traditional diagnosis relies on clinical evaluation,which is timeconsuming and subjective.Electroencephalography(EEG)signals provide an objective alternative,and machine learning methods can improve their diagnostic utility.AIM To develop an explainable EEG-based model for ADHD detection by integrating a novel combination ternary pattern(CTP)feature extractor with twin wavelet transform(TWT)for multilevel signal analysis,and to evaluate its effectiveness in providing accurate,channel-wise,and fusion-based classification results for objective and rapid ADHD diagnosis.METHODS A new EEG dataset containing more than 7000 segments from 137 ADHD patients and 150 controls was studied.A novel feature engineering framework was developed,combining a new CTP extractor with statistical features.A multilevel feature extraction structure was designed using a newly proposed TWT for signal decomposition.Extracted features were reduced to the most informative 263 using neighborhood component analysis.Channelwise classification was performed with k-nearest neighbors,followed by iterative majority voting across 20 EEG channels.RESULTS Single-channel analysis achieved up to 99.12%accuracy.By applying majority voting,overall classification accuracy increased to 99.97%,with similarly high sensitivity and specificity.CONCLUSION Our study introduces a large ADHD EEG dataset and a novel model integrating TWT and CTP.The model provides highly accurate,channel-wise,and fusion-based results,offering a promising objective tool for rapid ADHD diagnosis. 展开更多
关键词 Attention-deficit/hyperactivity disorder detection Combination ternary pattern Electroencephalography signal classification Explainable feature engineering Twin wavelet transform
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Dual-wavelength coherent beam combination and wide-angle beam steering via integrated optical phased arrays 认领 引用
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作者 Xiaobin Wang Yuqiu Zhang +9 位作者 Qiyu Wang Xu Zhao Jingye Chen Hongxiang Chang Zhongquan Nie Jinhai Zou Jian Wu Jinyong leng Pu Zhou Xiang’e Han 《Advanced Photonics Nexus》 CSCD 2026年第4期248-258,共11页
Integrated optical phased arrays(OPAs),owing to their high integration level and wide-angle beamsteering capability,are a key promising component for 3D/4D sensing and free-space optical communication.However,integrat... Integrated optical phased arrays(OPAs),owing to their high integration level and wide-angle beamsteering capability,are a key promising component for 3D/4D sensing and free-space optical communication.However,integrated OPAs typically employ a single-wavelength laser as the input light source,which limits their application in spectral imaging and secure communication.In this work,we propose and experimentally demonstrate a dual-wavelength coherent beam combining(CBC)scheme using a 64-element integrated OPA.A multiwavelength CBC model is established and validated with two wavelength pairs(1545/1555 and 1535∕1565 nm).Both simulation and experimental results confirm that the beam dispersion intensifies with the steering angle and wavelength separation.To overcome this inherent dispersion issue,we employ a stochastic parallel gradient descent algorithm with two avalanche photodiodes as feedback sensors,achieving an arbitrarily configurable angular separation between the two wavelength beams.Finally,we demonstrate the wide field of view beam-steering capability of the combined beam across a 60 deg(±30 deg)range.We provide a foundational framework for advancing multiwavelength OPA toward applications in spectral imaging and secure optical communications. 展开更多
关键词 integrated optical phased arrays coherent beam combination dual-wavelength stochastic parallel gradient descent algorithm
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Combination of bacteriophage-probiotics alleviates intestinal barrier dysfunction by regulating gut microbiome in a chick model of multidrug-resistant Salmonella infection 认领 引用
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作者 Youbin Choi Anna Kang +10 位作者 Eunsol Seo Daniel Junpyo Lee Junha Park Yeonsoo Kim Keesun Yu Cheol‑Heui Yun Ki Beom Jang Woo Kyun Kim Kwanseob Shim Darae Kang Younghoon Kim 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2026年第2期962-984,共23页
Background The rapid emergence of multidrug-resistant Salmonella in poultry demands alternative control strategies beyond conventional antibiotics.In this study,we evaluated a combination of lytic Salmonella-infecting... Background The rapid emergence of multidrug-resistant Salmonella in poultry demands alternative control strategies beyond conventional antibiotics.In this study,we evaluated a combination of lytic Salmonella-infecting bacteriophages(SLAM_phi ST45 and SLAM_phiST56)and a probiotic bacterium Limosilactobacillus reuteri(SLAM_LAR11)in a chick model challenged with Salmonella enterica serovar Typhimurium infection.Results Co-administration with two-phage cocktail and a probiotic showed markedly reduced Salmonella colonization in the gut and systemic organs of chicks,comparable to the effect of phage-only treatment.In contrast with phage-only treatment,the combined therapy significantly improved the rate of body-weight change from the day of infection to necropsy(P<0.0001)and alleviated infection-associated splenomegaly(P=0.028)and hepatomegaly(P=0.011).In the ileum,the villus height-to-crypt depth ratio(VH/CD)increased significantly(P=0.044).In the colon,expression of tight-junction genes OCLN(P=0.014),TJP1(P<0.0001),and MUC2(P=0.011)was elevated,whereas the pro-inflammatory cytokine IL6 was reduced(P=0.018).These improvements were accompanied,in the cecum,by trends toward decreases in Escherichia-Shigella(P=0.09)and Clostridium(P=0.16)and a trend toward an increase in Blautia(P=0.11);additionally,in the ileum,Lactobacillus(P=0.037)and Blautia(P=0.016)increased significantly,yielding a more balanced microbiota than with phage-only treatment.Consistently,levels of functional metabolites,including acetic acid(LDA=3.32)and lactic acid(LDA=5.29),were increased.Conclusion Taken together,these findings demonstrate that phage-probiotic co-administration not only enhances the clearance of multidrug-resistant Salmonella more effectively than phage treatment alone but also promotes intestinal health,highlighting its potential as an antibiotic-alternatives strategy to improve intestinal health and ensure food safety in poultry production systems. 展开更多
关键词 Antibiotic alternatives Gut microbiome Intestinal barrier Metabolites Multidrug-resistant Salmonella Phage-probiotic combination
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Clinical Analysis of Adverse Reactions Induced by the Combination of Cephalosporins with Various Western Medications 认领 引用
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作者 JIA Yongxia 《外文科技期刊数据库（文摘版）医药卫生》 2026年第7期032-036,共5页
Objective To analyze the clinical characteristics and related influencing factors of adverse reactions induced by the combination of cephalosporins with multiple Western medications. Methods A retrospective analysis w... Objective To analyze the clinical characteristics and related influencing factors of adverse reactions induced by the combination of cephalosporins with multiple Western medications. Methods A retrospective analysis was conducted on the medical records of 80 patients treated with cephalosporins at Xinjiang Kizilsu Kirghiz Autonomous Prefecture People's Hospital from February 2024 to December 2025. Patients were divided into a monotherapy group and a combination therapy group based on administration patterns. The categories of adverse reactions, medication-related time parameters, severity levels of adverse reactions, and abnormalities in laboratory test indicators were compared between the two groups. Results The overall incidence of adverse reactions was higher in the combination therapy group than in the monotherapy group (P<0.05). The duration of treatment, length of hospitalization, time to symptom resolution, and time to complete recovery were all longer in the combination therapy group than in the monotherapy group (P<0.05). The average severity score of adverse reactions was higher in the combination therapy group, with significant differences in the distribution across severity levels (P<0.05). The proportions of abnormal liver function, kidney function, and electrocardiogram findings, as well as the recovery times for laboratory parameters, were either higher or longer in the combination therapy group than in the monotherapy group (P<0.05). Conclusion The use of cephalosporins combined with multiple Western medications increases the probability of adverse reactions, prolongs recovery time, exacerbates the severity of adverse reactions, and elevates the risk of laboratory parameter abnormalities. Clinical practice must strengthen the management of combination therapies. 展开更多
关键词 Cephalosporins Combination therapy with Western drugs Adverse reactions Retrospective analysis Clinical characteristics
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Lamina combination characteristics and differential shale oil enrichment mechanisms of continental organic-rich shale:A case study of Triassic Yanchang Formation Chang 73 sub-member,Ordos Basin,NW China 认领 引用 被引量：9
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作者 NIU Xiaobing LYU Chengfu +5 位作者 FENG Shengbin ZHOU Qianshan XIN Honggang XIAO Yueye LI Cheng DAN Weidong 《Petroleum Exploration and Development》 SCIE 2025年第2期316-329,共14页
The lamina(combination)types,reservoir characteristics and shale oil occurrence states of organic-rich shale in the Triassic Yanchang Formation Chang 73 sub-member in the Ordos Basin were systematically investigated t... The lamina(combination)types,reservoir characteristics and shale oil occurrence states of organic-rich shale in the Triassic Yanchang Formation Chang 73 sub-member in the Ordos Basin were systematically investigated to reveal the main controlling factors of shale oil occurrence under different lamina combinations.The differential enrichment mechanisms and patterns of shale oil were discussed using the shale oil micro-migration characterization and evaluation methods from the perspectives of relay hydrocarbon supply,stepwise migration,and multi-stage differentiation.The results are obtained in five aspects.First,Chang 73 shale mainly develops five types of lamina combination,i.e.non-laminated shale,sandy laminated shale,tuffaceous laminated shale,mixed laminated shale,and organic-rich laminated shale.Second,shales with different lamina combinations are obviously different in the reservoir space.Specifically,shales with sandy laminae and tuffaceous laminae have a large number of intergranular pores,dissolution pores and hydrocarbon generation-induced fractures.The multi-scale pore and fracture system constitutes the main place for liquid hydrocarbon occurrence.Third,the occurrence and distribution of shale oil in shale with different lamina combinations are jointly controlled by organic matter abundance,reservoir property,thermal evolution degree,mineral composition and laminae scale.The micro-nano-scale pore-fracture networks within shales containing rigid laminae,particularly sandy and tuffaceous laminations,primarily contain free-state light hydrocarbon components.In contrast,adsorption-phase heavy hydrocarbon components predominantly occupy surfaces of organic matter assemblages,clay mineral matrices,and framework mineral particulates.Fourth,there is obvious shale oil micro-migration between shales with different lamina combinations in Chang 73.Generally,such micro-migration is stepwise in a sequence of organic-rich laminated shale→tuffaceous laminated shale→mixed laminated shale→sandy lamiated shale→non-laminated shale.Fifth,the relay hydrocarbon supply of organic matter under the control of the spatial superposition of shales with various laminae,the stepwise migration via multi-scale pore and fracture network,and the multi-differentiation in shales with different lamina combinations under the control of organic-inorganic interactions fundamentally decide the differences of shale oil components between shales with different lamina combinations. 展开更多
关键词 organic-rich shale lamina combination characteristics differential enrichment mechanism shale oil Chang 73 sub-member Triassic Yanchang Formation Ordos Basin
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Data-Driven Combination-Interval Prediction for Landslide Displacement Based on Copula and VMD-WOA-KELM Method 认领 引用 被引量：2
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作者 Longqi Li Yunhuang Yang +1 位作者 Tianzhi Zhou Mengyun Wang 《Journal of Earth Science》 SCIE CAS CSCD 2025年第1期291-306,共16页
To tackle the difficulties of the point prediction in quantifying the reliability of landslide displacement prediction,a data-driven combination-interval prediction method(CIPM)based on copula and variational-mode-dec... To tackle the difficulties of the point prediction in quantifying the reliability of landslide displacement prediction,a data-driven combination-interval prediction method(CIPM)based on copula and variational-mode-decomposition associated with kernel-based-extreme-learningmachine optimized by the whale optimization algorithm(VMD-WOA-KELM)is proposed in this paper.Firstly,the displacement is decomposed by VMD to three IMF components and a residual component of different fluctuation characteristics.The key impact factors of each IMF component are selected according to Copula model,and the corresponding WOA-KELM is established to conduct point prediction.Subsequently,the parametric method(PM)and non-parametric method(NPM)are used to estimate the prediction error probability density distribution(PDF)of each component,whose prediction interval(PI)under the 95%confidence level is also obtained.By means of the differential evolution algorithm(DE),a weighted combination model based on the PIs is built to construct the combination-interval(CI).Finally,the CIs of each component are added to generate the total PI.A comparative case study shows that the CIPM performs better in constructing landslide displacement PI with high performance. 展开更多
关键词 landslide displacement interval prediction combination method copula Landslides VMD-WOA-KELM
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A comparative study of various combination strategies for landslide susceptibility mapping considering landslide types 认领 引用 被引量：2
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作者 Lanbing Yu Biswajeet Pradhan Yang Wang 《Geoscience Frontiers》 SCIE CAS CSCD 2025年第2期243-261,共19页
Landslide susceptibility mapping (LSM) assists planners, local administrations, and decision-makers in preventing, mitigating and managing associated risks. This study proposes a novel DES-based framework that effecti... Landslide susceptibility mapping (LSM) assists planners, local administrations, and decision-makers in preventing, mitigating and managing associated risks. This study proposes a novel DES-based framework that effectively captures the spatial developmental patterns of different landslide types, leading to higher precision LSM. The Wanzhou district (administrative division) of Chongqing Province, southwestern China, was selected as the test area, encompassing 881 landslides classified into rockfalls, reservoir-affected (RA) landslides, and non-reservoir-affected (NRA) landslides. Subsequently, three inventory maps and sixteen environment factors were used as inputs, with multicollinearity and importance analyses used to select the best factor combination for three types of landslides. Finally, the susceptibilities of rockfalls, RA and NRA landslides were combined by six combination strategies: Maximum, Mean, Probability, Voting, Stacking, and Dynamic Ensemble Selection (DES) models, and the optimal strategy was identified by area under the receiver operating characteristic curves (AUC), confusion matrix, and landslide distribution statistic. For LSM of individual landslide types, ResNet consistently outperformed traditional machine learning models, achieving testing AUC values of 0.8925, 0.9427, and 0.6754 for rockfalls, RA, and NRA landslides, respectively. The evaluation of the combination strategies revealed that the DES model achieved the highest testing AUC value of 0.8779, followed by Stacking (0.8728), Maximum (0.8704), Probability (0.8669), and Voting (0.8653), whereas the widely-used Mean method performed the worst (0.8503), even lower than the non-classified LSM (0.8587). The findings offer a robust approach for mitigating future landslide risks and minimizing their adverse impacts, providing valuable insights for geohazard management and decision-making. 展开更多
关键词 Landslide susceptibility mapping Ensemble method Combination strategy Landslide types
Study on damage and failure characteristics of loaded gas-bearing rock-coal-rock combination structures 认领 引用 被引量：1
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作者 Feng Du Kai Wang +6 位作者 Wanyu Yang Jiazhi Sun Xiyang Fang Yiyang Zhang Longyong Shu Liang Wang Jiaxu Zhou 《Deep Underground Science and Engineering》 EI CAS CSCD 2025年第4期800-815,共16页
The essence of the outburst-rock burst compound dynamic disaster is the disaster behavior of the"gas-coal-surrounding rock"system under the comprehensive action of the stress field and the seepage field.Base... The essence of the outburst-rock burst compound dynamic disaster is the disaster behavior of the"gas-coal-surrounding rock"system under the comprehensive action of the stress field and the seepage field.Based on the geological occurrence characteristics of coal and rock in the roof,coal,and floor,this study combinedexperimental research and theoretical analysis to explore the effects of confining pressure,gas pressure,and axial loading rate on the mechanical behavior of gasbearing rock-coal-rock combination structures("RCR combination").The results show that both decreasing gas pressure and increasing confining pressure can improve the deformation capacity and bearing capacity of the RCR combination.When the gas pressure decreases from 1.5 to 0.5 MPa and the confining pressure increases from 3 to 9 MPa,the peak stress of the RCR combination increases by 15.83% and 184.02%,respectively.On increasing the axial loading rate,the peak stress of the RCR combination first increases and then decreases,and the elastic modulus continues to decrease.There is a good correspondence between stress and acoustic emission counts(AE),which can be used as a predictive index for judging rock fracture instability.Compared with rock,coal exerts much greater influence on the mechanical strength of the RCR combination.The theoretical analysis shows that the parameters m and F_0 mainly affect the peak stress of the RCR combination,and the speed of stress reduction after the peak of the RCR combination is influenced by the parameter m.The coal elastic modulus exerts greater influence on the bearing capacity of the RCR combination than the rock elastic modulus.When the elastic modulus of rocks increases from 10 to 25 GPa and that of coal increases from 2 to 5 GPa,the peak stress of the RCR combination increases by 9.87% and 8.97%,respectively. 展开更多
关键词 acoustic emission damage and failure energy analysis gas-bearing rock-coal-rock combination particle flow
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Analysis of vibration response characteristics of subway station and superstructure with hard combination 认领 引用 被引量：1
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作者 Jia Jinglong Xu Weiping +1 位作者 Liu Xu Wei Yong 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2025年第1期271-281,共11页
The vibration response and noise caused by subway trains can affect the safety and comfort of superstructures.To study the dynamic response characteristics of subway stations and superstructures under train loads with... The vibration response and noise caused by subway trains can affect the safety and comfort of superstructures.To study the dynamic response characteristics of subway stations and superstructures under train loads with a hard combination,a numerical model is developed in this study.The indoor model test verified the accuracy of the numerical model.The influence laws of different hard combinations,train operating speeds and modes were studied and evaluated accordingly.The results show that the frequency corresponding to the peak vibration acceleration level of each floor of the superstructure property is concentrated at 10–20 Hz.The vibration response decreases in the high-frequency parts and increases in the lowfrequency parts with increasing distance from the source.Furthermore,the factors,such as train operating speed,operating mode,and hard combination type,will affect the vibration of the superstructure.The vibration response under the reversible operation of the train is greater than that of the unidirectional operation.The operating speed of the train is proportional to its vibration response.The vibration amplification area appears between the middle and the top of the superstructure at a higher train speed.Its vibration acceleration level will exceed the limit value of relevant regulations,and vibration-damping measures are required.Within the scope of application,this study provides some suggestions for constructing subway stations and superstructures. 展开更多
关键词 subway station superstructure vibration response hard combination
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A new strategy of molecular breeding for optimal heading date and grain yield in rice by modulating elite allelic combinations of Ghd7,Hd3a,RFT1 and Gn1a 认领 引用 被引量：1
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作者 Qingmei Su Rongsheng Wang +9 位作者 Xiaomin Feng Mengyue Zhao Guanlin Zhu Qing Wang Fang Zhang Shaoyang Lin Yuhang Zhang Li Zhu Qian Qian Fan Chen 《The Crop Journal》 SCIE CAS CSCD 2025年第2期490-500,共11页
A later heading date generally leads to higher grain yield in favorable ecological regions;however,grain yield reaches a limit as the heading date exceeds a certain threshold.Ghd7 is the first cloned major gene that r... A later heading date generally leads to higher grain yield in favorable ecological regions;however,grain yield reaches a limit as the heading date exceeds a certain threshold.Ghd7 is the first cloned major gene that regulates heading date,plant height and grain number.Here,we investigated the relationship between Ghd7 and florigen genes Hd3a and RFT1,to determine their roles in regulating heading date and grain number under different photoperiods.Our results revealed that under long-day(LD)conditions,Hd3a acts prior to RFT1 to promote heading while negatively regulating plant height and grain number.In contrast,Ghd7 positively regulates heading date,plant height,and grain number by inhibiting both Hd3a and RFT1.Under short-day(SD)conditions,the functions of Hd3a and RFT1 remain consistent with those under LD conditions,but Ghd7 does not inhibit their expression,resulting in a weaker phenotypic effect compared to Hd3a.Additionally,under both LD and SD conditions,increased Ghd7 expression enhances its inhibitory effect on Hd3a and RFT1,leading to later heading and increased grain number;however,once the heading date exceeds 94 d,grain number no longer increases.Moreover,the gn1a allele increased grain number by 16.5%to 42.5%,while combinations of the elite alleles from Ghd7,Hd3a,RFT1,and Gn1a significantly increased grain number by up to 240.9%.Therefore,we propose a new breeding strategy to optimize the heading date and grain number using the Ghd7Hd3aRFT1gn1a combination of Ghd7,Hd3a,RFT1,and Gn1a under LD conditions,and the Ghd7hd3aRFT1gn1a combination under SD conditions.This strategy improved the yield of the high-quality Northeast variety Kongyu 131(KY131)by 69.1%in Beijing and 93.7%in Hainan.This strategy will greatly improve the efficiency of north-to-south adaptation in rice,providing theoretical guidance for expanding the geographical adaptability of rice varieties. 展开更多
关键词 Adaptation Elite gene combinations Oryza sativa Photoperiod response
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Damage location prediction of cement-sandstone combinations under axial force:Three-dimensional structure reconstruction and stress distribution simulation based onμ-CT 认领 引用 被引量：1
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作者 Zhong Li Zhiming Yin +3 位作者 Xingquan Zhang Tao Gu Fubin Xin Zhiqiang Huang 《Natural Gas Industry B》 2025年第4期405-415,共11页
Effective isolation between the cement sheath and the sandstone is crucial for the development and production of oil and gas wells in sandstone formations.In this study,a cement-sandstone composite(CSC)was prepared,an... Effective isolation between the cement sheath and the sandstone is crucial for the development and production of oil and gas wells in sandstone formations.In this study,a cement-sandstone composite(CSC)was prepared,and based onμ-CT three-dimensional reconstruction imaging and finite element analysis(FEA)techniques,the stress distribution and potential failure mechanism at the cement-sandstone bonding interface under axial loading were analyzed.The key findings are as follows:(1)stress concentrations are highly likely to form at the gap between the cement and sandstone interface and around interfacial voids,with Von Mises stress reaching critical levels of 18.0-20.0 MPa at these locations,significantly exceeding the stress magnitudes in well-bonded regions;(2)the phenomenon of local stress concentration driven by interfacial defects can be identified as the main basis for predicting damage location in interfacial debonding and continuous shear under axial load;(3)ensuring tight cementation at the cement-sandstone interface and minimizing interfacial voids are paramount for preventing stress-induced failure;(4)the critical Von Mises stress value of 20 MPa at the interface defect can be used as a benchmark for material selection and designed to ensure long-term integrity in oil and gas well applications subjected to similar axial loads.These findings contribute to a more accurate understanding of the failure mechanism of the cement-sandstone interface and to the precise design of material properties,thereby ensuring the long-term integrity of oil and gas well applications subjected to similar axial loads. 展开更多
关键词 Cement-sandstone combination μ-CT Stress distribution simulation Damage location prediction
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Combination of anlotinib and albumin-bound paclitaxel in 2ndline and above treatment of advanced gastric cancer:A retrospective study 认领 引用 被引量：1
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作者 Wen-Ming Liu Yi-Rui Liu +2 位作者 Yi Peng Jing Tang Xiao-Bing Li 《World Journal of Clinical Oncology》 2025年第4期119-129,共11页
BACKGROUND Chemotherapy combined with anti-angiogenic therapy has become an important strategy for the treatment of advanced gastric cancer(AGC);however,the regimen needs optimization.AIM To evaluate the efficacy of a... BACKGROUND Chemotherapy combined with anti-angiogenic therapy has become an important strategy for the treatment of advanced gastric cancer(AGC);however,the regimen needs optimization.AIM To evaluate the efficacy of albumin-bound paclitaxel(nab-ptx)combined with the small molecule vascular endothelial growth factor inhibitor anlotinib in secondline and beyond treatment of AGC.METHODS We collected data from AGC patients at our hospital who experienced disease progression after first-line chemotherapy and received anlotinib combined with nab-ptx.The primary endpoints included overall survival(OS)and progressionfree survival(PFS),while the secondary endpoints were objective response rate(ORR),disease control rate(DCR),and adverse events(AEs).RESULTS Preliminary results indicated that anlotinib combined with nab-ptx can provide significant efficacy in second-line or above treatment for AGC(median PFS=6.0 months,median OS=12.0 months),with an ORR of 42%and a DCR of 78%.Further analysis revealed that patients who experienced hypertension,proteinuria,and hand-foot syndrome during treatment had better efficacy compared to those who did not experience these AEs.Mechanistic studies suggest that this regimen likely exerts synergistic anti-tumor effects by activating the immune response through the reduction of regulatory T-cell proportions.Common adverse reactions included bone marrow suppression,peripheral neuropathy,hypertension,proteinuria,and hand-foot syndrome,which were manageable and resolved with appropriate interventions,indicating the promising application of this regimen in second-line or above treatment for AGC.CONCLUSION The combination of anlotinib and nab-ptx shows promising efficacy with fewer toxicities in AGC treatment.The regimen holds promise as a second-line treatment of AGC;however,its specific clinical value requires further research. 展开更多
关键词 Advanced gastric cancer Drug combination Albumin-bound paclitaxel Anlotinib Cohort study
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