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Flow Cytometric Analysis of DNA Content in Parotid Tumor and Its Contiguous Acini 认领 引用 被引量：1
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作者 朱声荣 王秀丽 +3 位作者 邵乐南 陈卫民 陈新明 吴慧华 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 2000年第1期86-88,共3页
Summary: To investigate the relationship between proliferative capacity of salivary gland cells in contiguous acini of parotid tumors and recurrent neoplasma, DNA contents of 30 fresh specimens of parotid were studied... Summary: To investigate the relationship between proliferative capacity of salivary gland cells in contiguous acini of parotid tumors and recurrent neoplasma, DNA contents of 30 fresh specimens of parotid were studied by using cytometry in tumors, normal and shallow or deep lobe acini of the masses. The results showed that the DI was 1. 369, S % 16. 95, PI 26. 18 in malignant tumors; DI was 1. 171, S % 12. 41, PI 15. 54 in recurrent pleomorphic adenoma; DI was 1. 141, S % 12. 74, PI 13. 07 in pleornorphic adenoma, DI was 0. 999, S % 5. 10, PI 8. 00 in normal acini. Analysis of variance showed there was a significant difference (P0. 05). It was concluded that the levels of DI and S % of parotid tumor and its contiguous acini are related to degree of malignancy or recurrent condition of the tumors, suggesting contiguous acini of parotid tumors had the strong capacity of proliferation, which might play an important role in recurrent or malignant change of the parotid tumors. 展开更多
关键词 parotid tumors contiguous acini flow cytometry DNA
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A Coherent Pattern Mining Algorithm Based on All Contiguous Column Bicluster 认领 引用 被引量：1
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作者 Xiaohui Hu Qiuhua Kuang +3 位作者 Qianhua Cai Yun Xue Weixing Zhou and Li Ying 《Journal of Artificial Intelligence and Technology》 2022年第3期80-92,共13页
Microarray contains a large matrix of information and has been widely used by biologists and bio data scientist for monitoring combinations of genes in different organisms.The coherent patterns in all continuous colum... Microarray contains a large matrix of information and has been widely used by biologists and bio data scientist for monitoring combinations of genes in different organisms.The coherent patterns in all continuous columns are mined in gene microarray data matrices.It is investigated,in this study,the coherent patterns in all continuous columns in gene microarray data matrix by developing the time series similarity measure for the coherent patterns in all continuous columns,as well as the evaluation function for verifying the proposed algorithm and the corresponding biclusters.The continuous time changes are taken into account in the coherent patterns in all continuous columns,and co-expression patterns in time series are searched.In order to use all the common information between sequences,a similarity measure for the coherent patterns in continuous columns is defined in this paper.To validate the efficiency of the similarity measure to mine biological information at continuous time points,an evaluation function is defined to measure biclusters,and an effective algorithm is proposed to mine the biclusters.Simulation experiments are conducted to verify the biological significance of the biclusters,which include synthetic datasets and real gene microarray datasets.The performance of the algorithm is analyzed,and the results show that the algorithm is highly efficient. 展开更多
关键词 contiguous column coherent biclusters gene data similarity measure time series
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ENVIRONMENTAL FEATURES AND WATERENVIRONMENTAL PROBLEMS IN THE CONTIGUOUSREGION OF JIANGSU,SHANGDONG,HENANAND ANHUI PROVINCES 认领 引用
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作者 季子修 于秀波 张琛 《Chinese Geographical Science》 SCIE 1999年第1期63-69,共7页
Owing to intensive human activities and the floods of the Huaihe River in historic peiod, the contiguous region of Jiangsu, Shandong, Henan and Anhui provinces is suffering from a variety of environmental problems and... Owing to intensive human activities and the floods of the Huaihe River in historic peiod, the contiguous region of Jiangsu, Shandong, Henan and Anhui provinces is suffering from a variety of environmental problems and naturaldisasters, of which water pollution and drought-flood disasters are most observable. Considering the special location andenvironmental status of the contiguous region, advices are proposed in the paper: perfecting trans-regional managementssystem of water environment incorporating basin management agencies in local government activities; strengthening cooperation of two agencies: water conservancy agency and environment protection agency; enhancing integrated control ofwater pollution and flood-drought disasters; taking the interests of the whole river into acount and paying attention to bothstorage and drainage; broadening sources of water supply and inceasing water delivery; controlling pollutant discharge,developing water saving production system. 展开更多
关键词 environmental problems drought and flood disasters water pollution contiguous region of Jiangsu Shandong Henan and Anhui provinces
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Measurement of self-development capacity in the contiguous destitute mountainous areas, China 认领 引用
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作者 XUE Yao-zu HUANG Lei 《Journal of Mountain Science》 SCIE CSCD 2021年第6期1646-1661,共16页
Affected by the mountainous location and ecological vulnerability, the incidence of poverty in contiguous destitute mountainous areas is higher than that in other regions of China. Regional selfdevelopment capacity is... Affected by the mountainous location and ecological vulnerability, the incidence of poverty in contiguous destitute mountainous areas is higher than that in other regions of China. Regional selfdevelopment capacity is an internal driving force for poverty reduction in contiguous destitute mountainous areas. This study selects 17 indicators from the four dimensions: industrial capacity, market capacity, spatial capacity and soft power to measure the overall self-development capacity of 658 counties in 14 different mountain areas in China. The results show that self-development capacity is at a low level and the development of the different regions is unbalanced. The self-development capacity is low in the southwest and high in the east and "low in the middle, high around" in each study region. It has achieved a certain degree of improvement in 2011, 2013 and 2015. From the perspective of the four dimensions, industrial capacity is the constraint on the promotion of self-development capacity. Based on this, we should develop green industries in line with local realities and achieve industrial poverty eradication, but the expansion of space capacity should take into account the resources and environmental carrying capacity in these areas and should not be blindly expanded. Local leaders should be made to improve the local education level and public service level, improve social infrastructure, develop reserve strength for the future, and enhance future development potential. 展开更多
关键词 Regional self-development capacity Contiguous Destitute Mountainous Areas Industrial capacity Market capacity Soft power
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Entry roof truss-bolt system test under the gob of contiguous seams 认领 引用
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作者 连传杰 徐卫亚 王亚杰 《Journal of Coal Science & Engineering(China)》 2007年第1期13-17,共5页
Roof bolt support system has been widely applied in the No.7, 9 seam in Caozhuang coal mine. However, it has not been able to be applied in the No.10-2 seam since the small interburden （2 m） between No.9 and No.10-2... Roof bolt support system has been widely applied in the No.7, 9 seam in Caozhuang coal mine. However, it has not been able to be applied in the No.10-2 seam since the small interburden （2 m） between No.9 and No.10-2 seam. The No.9 and No.10-2 seams are contiguous seams. The No.9 seam has been mined out and the No.10-2 seam will be mined under the gob of the No.9 seam. The roof strata of the No.10-2 seam may have been weakened and fractured due to the shear failure caused by the No.9 seam mining activities. The steel beam sets spaced at 0.8 m have been used to support the entry of the No.10-2 seam. In order to speed up the advance rate and cut entry development cost, a test area, using roof bolt in conjunction with truss-system, was successfully conducted. This paper presents the support system design, application of designed system, and the test results. Test results provide a cheaper, quicker, and safer way to support entry for the No.10-2 seam. 展开更多
关键词 truss-bolt system gob finite element method（FEM） contiguous seams installed load of bolt
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Catalytic diastereoselective construction of multiple contiguous quaternary carbon stereocenters via [2+2] cycloaddition and mechanistic insight 认领 引用 被引量：1
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作者 Xi Wang Fujie Liu Tao Xu 《Chinese Chemical Letters》 SCIE CAS CSCD 2023年第3期288-292,共5页
Multiple contiguous quaternary carbon stereocenters(CQS) are highly challenging, yet important structural motifs in organic synthesis. Here, we describe a visible light induced catalytic [2 + 2] cycloaddition approach... Multiple contiguous quaternary carbon stereocenters(CQS) are highly challenging, yet important structural motifs in organic synthesis. Here, we describe a visible light induced catalytic [2 + 2] cycloaddition approach that constructed up to four CQS in a pentacyclic fused ring system diastereoselectively, from the readily accessible dienamides with pendent heteroaryls. Variously substituted dienamides have been cyclized with heteroaryls to provide a range of novel CQS-containing scaffolds(26 examples, up to 96%yield and >20:1 dr ratio). Mechanistic studies revealed that it may proceed through an uncommon β-C radical initiated 7-endo cyclization from the biradical intermediate. 展开更多
关键词 Contiguous quaternary carbon stereocenters [2+2]Cycloaddition Fused ring system
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Micro Calcification Detection in Mammogram Images Using Contiguous Convolutional Neural Network Algorithm 认领 引用
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作者 P.Gomathi C.Muniraj P.S.Periasamy 《Computer Systems Science & Engineering》 SCIE EI 2023年第5期1887-1899,共13页
The mortality rate decreases as the early detection of Breast Cancer(BC)methods are emerging very fast,and when the starting stage of BC is detected,it is curable.The early detection of the disease depends on the imag... The mortality rate decreases as the early detection of Breast Cancer(BC)methods are emerging very fast,and when the starting stage of BC is detected,it is curable.The early detection of the disease depends on the image processing techniques,and it is used to identify the disease easily and accurately,especially the micro calcifications are visible on mammography when they are 0.1 mm or bigger,and cancer cells are about 0.03 mm,which is crucial for identifying in the BC area.To achieve this micro calcification in the BC images,it is necessary to focus on the four main steps presented in this work.There are three significant stages of the process assigned to find the BC using a thermal image;the image processing procedures are described below.In the first stage of the process,the Gaussian filter technique is implemented to magnify the screening image.During the second stage,BC detection is separated from the pre-processed image.The Proposed Versatile K-means clustering(VKC)algorithm with segmentation is used to identify the BC detection form of the screening image.The centroids are then recalculated using proposed VKC,which takes the mean of all data points allocated to that centroid’s cluster,lowering the overall intracluster variance in comparison to the prior phase.The“means”in K-means refers to the process of averaging the data and determining a new centroid.This process eliminates unnecessary areas of interest.First,the mammogram screening image information is taken from the patient and begins with the Contiguous Convolutional Neural Network(CCNN)method.The proposed CCNN is used to classify the Micro calcification in the BC spot using the feature values is the fourth stage of the process.The assess the presence of high-definition digital infrared thermography technology and knowledge base and suggests that future diagnostic and treatment services in breast cancer imaging will be developed.The use of sophisticated CCNN techniques in thermography is being developed to attain a greater level of consistency.The implemented(CCNN)technique’s performance is examined with different classification parameters like Recall,Precision,F-measure and accuracy.Finally,the Breast Cancer stages will be classified based on the true positive and true negative values. 展开更多
关键词 Contiguous Convolutional Neural Network(CCNN) Gaussian filter Versatile K-Means Clustering(VKC)algorithm mammogram cancer detection
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Novel Contiguous Cross Propagation Neural Network Built CAD for Lung Cancer 认领 引用
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作者 A.Alice Blessie P.Ramesh 《Computer Systems Science & Engineering》 SCIE EI 2023年第2期1467-1484,共18页
The present progress of visual-based detection of the diseased area of a malady plays an essential part in the medicalfield.In that case,the image proces-sing is performed to improve the image data,wherein it inhibits ... The present progress of visual-based detection of the diseased area of a malady plays an essential part in the medicalfield.In that case,the image proces-sing is performed to improve the image data,wherein it inhibits unintended dis-tortion of image features or it enhances further processing in various applications andfields.This helps to show better results especially for diagnosing diseases.Of late the early prediction of cancer is necessary to prevent disease-causing pro-blems.This work is proposed to identify lung cancer using lung computed tomo-graphy(CT)scan images.It helps to identify cancer cells’affected areas.In the present work,the original input image from Lung Image Database Consortium(LIDC)typically suffers from noise problems.To overcome this,the Gaborfilter used for image processing is highly enhanced.In the next stage,the Spherical Iterative Refinement Clustering(SIRC)algorithm identifies cancer-suspected areas on the CT scan image.This approach can help radiologists and medical experts recognize cancer diseases and syndromes so that serious progress can be avoided in the early stages.These new methods help to remove unwanted por-tions of the CT image and better utilization the image.The subspace extraction of features approach is beneficial for evaluating lung cancer.This paper introduces a novel approach called Contiguous Cross Propagation Neural Network that tends to locate regions afflicted by lung cancer using CT scan pictures(CCPNN).By using the feature values from the fourth step of the procedure,the proposed CCPNN tends to categorize the lesion in the lung nodular site.The efficiency of the suggested CCPNN approach is evaluated using classification metrics such as recall(%),precision(%),F-measure(percent),and accuracy(%).Finally,the incorrect classification ratios are determined to compare the trained networks’effectiveness,through these parameters of CCPNN,it obtains the outstanding per-formance of 98.06%and it has provided the lowest false ratio of 1.8%. 展开更多
关键词 Contiguous cross propagation neural network(CCPNN) Gaborfilter
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A JUNCTURE FOR PROMOTING EAST-WEST ECONOMIC PROSPERITY IN CHINA-SUGGESTIONS ON ECONOMIC DEVELOPMENT IN CONTIGUOUS AREA OF JIN-SHAN-MONG 认领 引用
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作者 Yang LianglinPeople’s Ropublic of China 《Journal of Geographical Sciences》 1995年第3期77-80,共4页
The short artide higuights that both location and economic deveopmat of the area is of spedal siwificance in position and funedon.Suggesons covering five aspects are thus raised on econondc deveopmat of the area.
关键词 Jin-Shan-Meng contiguous area economic development,suggestions
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Organocatalytic Asymmetric Oxa-[3+3]-annulation for Chiral Tricyclic Chromans with Contiguous Stereocenters 认领 引用
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作者 Meng-Yuan Wu Xu-Yi Huang +1 位作者 Beiling Gao Guang-Jian Mei 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2026年第1期47-54,共8页
A bifunctional squaramide-catalyzed asymmetric synthesis of chiral tricyclic chromans featuring three contiguous stereocenters has been successfully developed.This innovative strategy relies on the synergistic activat... A bifunctional squaramide-catalyzed asymmetric synthesis of chiral tricyclic chromans featuring three contiguous stereocenters has been successfully developed.This innovative strategy relies on the synergistic activation of 3-aminophenol derivatives and 4-benzylidenepyrrolidine-2,3-diones by the chiral catalyst,enabling an efficient asymmetric oxa-[3+3]-annulation reaction.The protocol exhibits a broad substrate scope with 34 diverse examples,delivering moderate-to-good yields ranging from 64%to 81%,excellent enantioselectivity(up to 99%ee),and tunable diastereoselectivity(dr up to 15:1).Notably,halogen substitution plays a pivotal role in dramatically enhancing stereocontrol,further optimizing the diastereoselectivity of the target products.To validate its practical utility,gram-scale synthesis was successfully conducted without compromising yield or stereoselectivity,and subsequent derivatization reactions confirmed the versatility of the obtained chiral tricyclic chromans.This metal-free,mild reaction system not only enriches the synthetic toolbox for constructing complex chroman architectures,but also provides a versatile platform for the asymmetric synthesis of bioactive molecules containing the chiral tricyclic chroman skeleton,highlighting the significance of enantioselectivity and diastereoselectivity in accessing functionalized heterocyclic compounds. 展开更多
关键词 Chiral tricyclic chromans Squaramide catalysis Asymmetric synthesis Oxa-[3+3]-annulation Contiguous stereocenters Organocatalytic 3-Aminophenol 2,3-dioxopyrrolidine Bioactive molecules
PROBLEMS AND COUNTERMEASURES FOR RESOURCES DEVELOPMENT AND ENVIRONMENTAL RENOVATION IN THE CONTIGUOUS AREA OF SHANXI,SHAANXI AND INNER MONGOLIA 认领 引用 被引量：1
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作者 Guo Shaoli Commission for Integrated Survey of Natural Resources under Chinese Academy of Sciences and National Planning Committee, Beijing 《干旱区资源与环境》 1993年第Z1期415-418,共4页
The studied area consists of 16 counties belonging to 3 provinces or autonomous re-gion, which are Hequ, Baode, Pianguan and Xinxian counties of Shanxi Province; Yulin,Shenmu, Fugu, Hengshan, Jingbian and Dingbian cou... The studied area consists of 16 counties belonging to 3 provinces or autonomous re-gion, which are Hequ, Baode, Pianguan and Xinxian counties of Shanxi Province; Yulin,Shenmu, Fugu, Hengshan, Jingbian and Dingbian counties of Shaanxi Province;Dongsheng, Tuoketuo, Qingshuihe counties and Yijinhuoluo, Dalate, Zhungeer banners 展开更多
关键词 The Contiguous Area of Shanxi Shaanxi and Inner Mongolia Resources Development Environ mental Renovation
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China’s poorest counties are transitioning towards low-carbon poverty alleviation 认领 引用
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作者 Jinhai Li Feifei Lin +1 位作者 Peng Cheng Xuesong Kong 《Geography and Sustainability》 CSCD 2026年第3期38-50,共13页
Low-carbon development in poverty-stricken areas is crucial for the Sustainable Development Goals.However,the relationship between poverty alleviation and carbon emissions in impoverished regions remains unclear.This ... Low-carbon development in poverty-stricken areas is crucial for the Sustainable Development Goals.However,the relationship between poverty alleviation and carbon emissions in impoverished regions remains unclear.This study calculated land-use carbon emissions of 505 counties in China’s contiguous poor areas,which suffer from extreme poverty and are the most difficult to lift out of poverty,established evaluation frameworks for carbon emissions efficiency and multidimensional poverty alleviation,and employed an improved coupling coordination model to assess the relationship.Results showed that all counties achieved remarkable multidimensional poverty alleviation from 2000 to 2020 while the speed varied among regions.After initial deterioration,emissions efficiency exhibited significant improvements during 2010-2020.This reversal was mainly driven by reduced carbon intensity and carbon emissions per unit of construction land.Analysis revealed 505 counties’transformation from an uncoordinated“low development-low carbon”state toward a sustainable“high development-low carbon”state.These findings evidence that poverty alleviation development and low-carbon target can be compatible,offering valuable insights for sustainable development in global underdeveloped regions. 展开更多
关键词 Multidimensional poverty alleviation Contiguous poor areas Coupling coordination Low-carbon development Sustainable development Carbon emissions
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Gene deletion analysis of a Chinese boy with Xp21 contiguous gene deletion syndrome 认领 引用 被引量：1
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作者 麻宏伟 姜俊 +3 位作者 王岳平 王志超 陈丽英 松尾雅文 《Chinese Medical Journal》 SCIE CAS 2004年第5期789-791,共3页
关键词 Xp21 contiguous gene deletion syndrome deletion extent ·PCR
Discovery and enantioselective total synthesis of antitumor agent asperfilasin A via a regio- and diastereoselective Nazarov cyclization 认领 引用
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作者 Fengqing Wang Changxing Qi +8 位作者 Chunmei Chen Qin Li Qingyi Tong Weiguang Sun Zhengxi Hu Minyan Wang Hucheng Zhu Lianghu Gu Yonghui Zhang 《Chinese Chemical Letters》 SCIE CAS CSCD 2025年第6期397-403,共7页
Asperfilasin A(1),featuring a unique 5/5 cyclopenta[c]pyrrol-one bicyclic core,represents a newly discovered skeletal cytochalasan isolated from Aspergillus flavipes.The enantioselective total synthesis was efficientl... Asperfilasin A(1),featuring a unique 5/5 cyclopenta[c]pyrrol-one bicyclic core,represents a newly discovered skeletal cytochalasan isolated from Aspergillus flavipes.The enantioselective total synthesis was efficiently accomplished from the key intermediate(S)-6 with three contiguous stereocenters in 5 steps and the synthetic 1 induced G2/M-phase cell cycle arrest of HT29 cells and apoptosis of HL60 and NB4 cells by activation of caspase-3 and degradation of PARP.(S)-6,bearing three contiguous chiral centers,was efficiently constructed by a novel Nazarov cyclization reaction containing basic nitrogen,which was less developed,primarily due to the incompatibility of basic nitrogen under acidic reaction conditions.This reaction allows a wide range of pentadienone substrates containing basic nitrogen to undergo Nazarov cyclization in a single regioselective and diastereoselective manner and is capable of generating three stereocenters simultaneously.Furthermore,the mechanism of the Nazarov cyclization and the origin of the regio-and diastereoselectivity were elucidated by DFT calculations and deuteration experiments,providing valuable insights into the reaction and serving as a guide for future applications involving substrates containing basic nitrogen. 展开更多
关键词 Cytochalasan Antitumor activity Nazarov cyclization Basic nitrogen Contiguous stereocenters DFT calculations
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Telomere-to-telomere and gap-free genome assembly of a susceptible grapevine species(Thompson Seedless)to facilitate grape functional genomics 认领 引用 被引量：5
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作者 Xianhang Wang Mingxing Tu +10 位作者 Ya Wang Yali Zhang Wuchen Yin Jinghao Fang Min Gao Zhi Li Wei Zhan Yulin Fang Junyang Song Zhumei Xi Xiping Wang 《Horticulture Research》 SCIE CSCD 2024年第1期272-286,共15页
Grapes are globally recognized as economically significant fruit trees.Among grape varieties,Thompson Seedless holds paramount influence for fresh consumption and for extensive applications in winemaking,drying,and ju... Grapes are globally recognized as economically significant fruit trees.Among grape varieties,Thompson Seedless holds paramount influence for fresh consumption and for extensive applications in winemaking,drying,and juicing.This variety is one of the most efficient genotypes for grape genetic modification.However,the lack of a high-quality genome has impeded effective breeding efforts.Here,we present the high-quality reference genome of Thompson Seedless with all 19 chromosomes represented as 19 contiguous sequences(N50=27.1 Mb)with zero gaps and prediction of all telomeres and centromeres.Compared with the previous assembly(TSv1 version),the new assembly incorporates an additional 31.5 Mb of high-quality sequenced data with annotation of a total of 30397 protein-coding genes.We also performed a meticulous analysis to identify nucleotide-binding leucine-rich repeat genes(NLRs)in Thompson Seedless and two wild grape varieties renowned for their disease resistance.Our analysis revealed a significant reduction in the number of two types of NLRs,TIR-NB-LRR(TNL)and CC-NB-LRR(CNL),in Thompson Seedless,which may have led to its sensitivity to many fungal diseases,such as powdery mildew,and an increase in the number of a third type,RPW8(resistance to powderymildew8)-NB-LRR(RNL).Subsequently,transcriptome analysis showed significant enrichment of NLRs during powderymildew infection,emphasizing the pivotal role of these elements in grapevine’s defense against powdery mildew.The successful assembly of a high-quality Thompson Seedless reference genome significantly contributes to grape genomics research,providing insight into the importance of seedlessness,disease resistance,and color traits,and these data can be used to facilitate grape molecular breeding efforts. 展开更多
关键词 nucleotide binding leucine rich repeat genes functional genomics telomere telomere gap free genome assembly contiguous seq thompson seedless grapevine high quality reference genome
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Analyzing multidimensional measures of poverty and their influences in China's Qinba Mountains 认领 引用 被引量：3
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作者 Wenxian Jiao 《Chinese Journal of Population,Resources and Environment》 2020年第3期214-221,共8页
We use the Alkire–Foster poverty measure and decomposition method to study multidimensional poverty in the Qinling–Daba contiguous poor area of China's Henan Province.We examine absolute,relative,and multidimens... We use the Alkire–Foster poverty measure and decomposition method to study multidimensional poverty in the Qinling–Daba contiguous poor area of China's Henan Province.We examine absolute,relative,and multidimensional poverty focusing on heads of household and family characteristics as constituents of escaping each.We find that the multidimensional poverty index declines to a low level as values of k increase.Combining first-order random dominance with second-order stochastic dominance quickly determines rankings in the multidimensional poverty index.Increasing non-agricultural income emerges as the most important influence on escaping rural poverty,whereas households with elderly and children are at greatest risk for falling into poverty. 展开更多
关键词 Contiguous poor areas Absolute poverty Relative poverty Multidimensional poverty Stochastic dominance curve
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Rigorous Running Time Analysis of a Simple Immune-Based Multi-Objective Optimizer for Bi-Objective Pseudo-Boolean Functions 认领 引用
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作者 ZHOU Shiyuan PENG Xue +1 位作者 WANG Yinglin XIA Xiaoyun 《Journal of Shanghai Jiaotong university(Science)》 EI 2018年第6期827-833,共7页
A simple immune-based multi-objective optimizer(IBMO) is proposed, and a rigorous running time analysis of IBMO on three proposed bi-objective pseudo-Boolean functions(Bi-Trap, Bi-Plateau and Bi-Jump) is presented. Th... A simple immune-based multi-objective optimizer(IBMO) is proposed, and a rigorous running time analysis of IBMO on three proposed bi-objective pseudo-Boolean functions(Bi-Trap, Bi-Plateau and Bi-Jump) is presented. The running time of a global simple evolutionary multi-objective optimizer(GSEMO) using standard bit mutation operator with IBMO using somatic contiguous hypermutation(CHM) operator is compared with these three functions. The results show that the immune-based hypermutation can significantly beat standard bit mutation on some well-known multi-objective pseudo-Boolean functions. The proofs allow us to understand the relationship between the characteristics of the problems and the features of the algorithms more deeply. These analysis results also give us a good inspiration to analyze and design a bio-inspired search heuristics. 展开更多
关键词 evolutionary algorithm running time analysis somatic contiguous hypermutation
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Optimized CUDA Implementation to Improve the Performance of Bundle Adjustment Algorithm on GPUs 认领 引用 被引量：1
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作者 Pranay R. Kommera Suresh S. Muknahallipatna John E. McInroy 《Journal of Software Engineering and Applications》 2024年第4期172-201,共30页
The 3D reconstruction pipeline uses the Bundle Adjustment algorithm to refine the camera and point parameters. The Bundle Adjustment algorithm is a compute-intensive algorithm, and many researchers have improved its p... The 3D reconstruction pipeline uses the Bundle Adjustment algorithm to refine the camera and point parameters. The Bundle Adjustment algorithm is a compute-intensive algorithm, and many researchers have improved its performance by implementing the algorithm on GPUs. In the previous research work, “Improving Accuracy and Computational Burden of Bundle Adjustment Algorithm using GPUs,” the authors demonstrated first the Bundle Adjustment algorithmic performance improvement by reducing the mean square error using an additional radial distorting parameter and explicitly computed analytical derivatives and reducing the computational burden of the Bundle Adjustment algorithm using GPUs. The naïve implementation of the CUDA code, a speedup of 10× for the largest dataset of 13,678 cameras, 4,455,747 points, and 28,975,571 projections was achieved. In this paper, we present the optimization of the Bundle Adjustment algorithm CUDA code on GPUs to achieve higher speedup. We propose a new data memory layout for the parameters in the Bundle Adjustment algorithm, resulting in contiguous memory access. We demonstrate that it improves the memory throughput on the GPUs, thereby improving the overall performance. We also demonstrate an increase in the computational throughput of the algorithm by optimizing the CUDA kernels to utilize the GPU resources effectively. A comparative performance study of explicitly computing an algorithm parameter versus using the Jacobians instead is presented. In the previous work, the Bundle Adjustment algorithm failed to converge for certain datasets due to several block matrices of the cameras in the augmented normal equation, resulting in rank-deficient matrices. In this work, we identify the cameras that cause rank-deficient matrices and preprocess the datasets to ensure the convergence of the BA algorithm. Our optimized CUDA implementation achieves convergence of the Bundle Adjustment algorithm in around 22 seconds for the largest dataset compared to 654 seconds for the sequential implementation, resulting in a speedup of 30×. Our optimized CUDA implementation presented in this paper has achieved a 3× speedup for the largest dataset compared to the previous naïve CUDA implementation. 展开更多
关键词 Scene Reconstruction Bundle Adjustment Levenberg-Marquardt Non-Linear Least Squares Memory Throughput Computational Throughput Contiguous Memory Access CUDA Optimization
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EFFECT OF Mo AND Mo_2C ON THE MICROSTRUCTURE AND PROPERTIES OF THE CERMETS BASED ON Ti(C,N) 认领 引用 被引量：14
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作者 S.Q. Zhou W. Zhao +1 位作者 W.H. Xiong Y.N. Zhou 《Acta Metallurgica Sinica(English Letters)》 EI CAS 2008年第3期211-219,共9页
Effect of Mo and Mo2 C on the microstructure and properties of Ti（C,N）-based cermets was investigated in this article. The results have indicated that the weight percentage of Mo from 5 to 10 can reduce Ti（C,N） gr... Effect of Mo and Mo2 C on the microstructure and properties of Ti（C,N）-based cermets was investigated in this article. The results have indicated that the weight percentage of Mo from 5 to 10 can reduce Ti（C,N） grain diameter and thickness of the rim, and Ti（C,N） grain can be wetted by Ni-Cu-Mo liquid so as to get small contiguity of Ti（C,N） grain. In that way, the transverse rupture strength of Ti（C,N）-based cermets has reached 1800-1900 MPa; the fracture toughness has been due to 16-18 MPa.m1/2. But 15 wt pct Mo was not more effective on Ti（C,N）-based cermets, because the thickness of the rim becomes larger. In the circumstance of Mo2 C, 5 wt pct Mo2 C was good for microstructure and properties of Ti（C,N）-based cermets, but 11 wt pct Mo2C has resulted in larger contiguity of Ti（C,N） grain and big Ti（C,N） grain diameter so as to reduce transverse rupture strength and fracture toughness. So that, the effect of Mo on Ti（C,N）-based cermets is better than Mo2C. 展开更多
关键词 Cermet Transverse rupture strength （TRS） Contiguity Fracture toughness
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A telomere-to-telomere reference genome of ficus(Ficus hispida)provides new insights into sex determination 认领 引用 被引量：5
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作者 Zhenyang Liao Tianwen Zhang +7 位作者 Wenlong Lei Yibin Wang Jiaxin Yu Yinghao Wang Kun Chai Gang Wang Huahao Zhang Xingtan Zhang 《Horticulture Research》 SCIE CSCD 2024年第1期234-242,共9页
A high-quality reference genome is indispensable for resolving biologically essential traits.Ficus hispida is a dioecious plant.A complete Ficus reference genome will be crucial for understanding their sex evolution a... A high-quality reference genome is indispensable for resolving biologically essential traits.Ficus hispida is a dioecious plant.A complete Ficus reference genome will be crucial for understanding their sex evolution and important biological characteristics,such as aerial roots,mutualistic symbiosis with ficus-wasps,and fruiting from old stems.Here,we generated a telomere-to-telomere(T2T)genome for F.hispida using PacBio HiFi and Oxford Nanopore Ultra-long sequencing technologies.The genome contiguity and completeness has shown improvement compared with the previously released genome,with the annotation of six centromeres and 28 telomeres.We have refined our previously reported 2-Mb male-specific region into a 7.2-Mb genomic region containing 51 newly predicted genes and candidate sex-determination genes AG2 and AG3.Many of these genes showed extremely low expression,likely attributed to hypermethylation in the gene body and promoter regions.Gene regulatory networks(GRNs)revealed that AG2 and AG3 are related to the regulation of stamen development in male f lowers,while the AG1 gene is responsible for regulating female f lowers’defense responses and secondary metabolite processes.Comparative analysis of GRNs showed that the NAC,WRKY,and MYB transcription factor families dominate the female GRN,whereas the MADS and MYB transcription factor families are prevalent in the male GRN. 展开更多
关键词 genome contiguity resolving biologically essential traitsficus hispida sex evolution pacbio hifi fruiting old telomere telomere reference genome aerial rootsmutualistic symbiosis
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