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Lymph Node Mapping with Carbon Nanoparticles and the Risk Factors of Lymph Node Metastasis in Gastric Cancer 认领 引用 被引量：11
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作者 Hui WANG Man-man CHEN +3 位作者 Guang-sheng ZHU Mao-guang MA Han-song DU Yue-ping LONG 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 2016年第6期865-870,共6页
The study aimed to examine the applicability of carbon nanoparticles as a tracer for lymph node mapping and the related factors of lymph node and No.8p subgroup metastasis in patients with gastric cancer.Clinical data... The study aimed to examine the applicability of carbon nanoparticles as a tracer for lymph node mapping and the related factors of lymph node and No.8p subgroup metastasis in patients with gastric cancer.Clinical data of 50 patients with gastric cancer,who had not received treatment preoperatively and underwent gastrectomy in Department of Gastrointestinal Surgery,Wuhan Union Hospital,between October 2014 and August 2015,were retrospectively analyzed.These patients were found to have no distant metastasis preoperatively.Thirty-five out of 50 patients were subjected to lymphatic mapping technique using carbon nanoparticles as the tracer,and the rest 15 cases did not experience the lymphatic mapping and served as controls.The sensitivity,specificity,false positive rate and false negative rate were calculated according to the number of lymph nodes,and the staining and metastasis condition of lymph nodes.The diagnostic value of carbon nanoparticles on metastatic lymph nodes was evaluated.The relationship between the metastasis of lymph nodes or subgroup No.8p lymph nodes and clinicopathologic features was analyzed by χ^2-test or Fisher＇s exact test.All patients underwent D2 surgery（lymph node dissection including all the group 1 and group 2 nodes） plus the dissection of the subgroup No.8p lymph nodes.It was found that the average number of harvested lymph nodes in lymphatic mapping technique group（45.7±14.5） was greater than that in control group（39.2±11.7）,but the difference was not significantly different（P=0.138〉0.05）.The success rate,the accuracy,sensitivity,specificity and false negative rate was 97%,57%,28%,62% and 72% respectively.The metastasis of lymph nodes was correlated to the depth of cancer invasion（T stage）（P=0.004〈0.05）,and the metastasis of No.8p lymph nodes was correlated to the extent of lymph node involvement（N stage）（P=0.007〈0.05）.Six cases had lymph node metastasis in subgroup No.8p,and their TNM stages and clinical stages were as follows：T1N2M0 ⅡA,T3N3M0 ⅢB,T4 a N3M0 ⅢC,T4 a N3M0 ⅢC,T4 a N3M0 ⅢC,and T4 b N3M0 ⅢC.In conclusion,our study indicated that carbon nanoparticles failed to show good selectivity for metastatic lymph nodes;the result of lymphatic mapping does not achieve a satisfactory performance;the incidence of lymph node metastasis may increase,accompanying with the increase of the depth of cancer invasion;No.8p lymph node metastasis tends to occur for gastric carcinoma patients with the extent of lymph node metastasis over N2 stage. 展开更多
关键词 stomach neoplasms lymph node metastasis carbon nanoparticles lymph node mapping No.8p lymph nodes
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What's wrong with sentinel node mapping in colon cancer? 认领 引用 被引量：2
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作者 Ronan A Cahill 《World Journal of Gastroenterology》 SCIE CAS 2007年第47期6291-6294,共4页
Despite near-universal embrace of the concept and clinical relevance of lymphatic mapping for sentinel node identification and analysis for cancers of the breast and integument,the same technique has struggled to a fi... Despite near-universal embrace of the concept and clinical relevance of lymphatic mapping for sentinel node identification and analysis for cancers of the breast and integument,the same technique has struggled to a find a role in gastrointestinal cancers in general and,perhaps,in colon cancer in particular. Despite many studies demonstrating its feasibility in malignancies of the large bowel,concern is continually aroused by the variable and often unacceptably low sensitivity rates. Additionally,many confess uncertainty as to what benefit it could ever confer to patients even if it were proven sufficiently accurate given that standard surgical resection incorporates mesenteric resection anyway. However,the huge impact sentinel node mapping has had on clinical practice in certain cancers means that each of these aspects merit careful reconsideration,from very first principles. 展开更多
关键词 Sentinel node Lymphatic mapping Colon cancer
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Lymph node mapping in rabbit liver cancer with nanocarbon and methylene blue injecta 认领 引用 被引量：3
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作者 Zhong Li 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2013年第5期400-403,共4页
Objective:To discuss the value of lymph node mapping in rabbit liver cancer with nanocarbon and methylene blue injecta.Methods:Rabbit liver cancer model was established by transplanting VX2 cells with laparotomy in ce... Objective:To discuss the value of lymph node mapping in rabbit liver cancer with nanocarbon and methylene blue injecta.Methods:Rabbit liver cancer model was established by transplanting VX2 cells with laparotomy in celiac planting method.Twenty Japan white rabbits were divided into two groups randomly.Each group had 10 rabbits.Lymph node mapping in (wo groups rabbit liver cancer were observed.Two groups rabbit liver cancer and local lymph nodes were removed.The number and location of local lymph nodes were recorded,and then the samples were obtained from both groups.Results:The lymph nodes dyed time was(100.50±29.92) s in nanocarbon group,and(11.20+4.18) s in methylene blue group with statistical significance between two groups(P=0.000).In the comparison of lymph node fading time,nanocarbon group was(2.22±0.74) h,methylene blue group was(1.63+0.54) h,nanocarbon group was longer than the methylene blue group,but without statistical significance(P=0.058).The accuracy was 87.5% (35/40) in methylene blue group,while,the nanocarbon group was 87.2%(34/39),with statistical significance(P=1.000).Conclusions:Experimental results show that application of nanocarbon injection and methylene blue injection during resection of liver cancer and local lymph nodes in rabbit liver cancer model has obvious tracer function in liver cancer and lymphatic drainage. It can reduce the complexity and risk of the operation,and avoid the blindness in the process of traditional lymph node dissection surgery.Besides,they can effectively reduce the number of residual lymph nodes after operation.It can achieve the lymph node dissection more thoroughly, promptly,easily and safely. 展开更多
关键词 Nanocarbon injecta Methylene blue injecta Lymph mapping Lymph node dissection Liver cancer model
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LYMPHATIC MAPPING AND SENTINEL LYMPH NODE BIOPSY IN THE PATIENTS WITH BREAST CANCER 认领 引用
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作者 刘国津 范志民 +4 位作者 唐强 杨明 付彤 张宏 宋冬 《Chinese Journal of Cancer Research》 CAS 2000年第4期293-295,共3页
Objective: To identify the feasibility of the lymphatic mapping and sentinel node biopsy (SNB) in patients with breast cancer and to examine whether the characteristics of the sentinel lymph node (SLN) accurately pred... Objective: To identify the feasibility of the lymphatic mapping and sentinel node biopsy (SNB) in patients with breast cancer and to examine whether the characteristics of the sentinel lymph node (SLN) accurately predict the status of axillary node. Methods: 33 patients with breast cancer intraoperatively and postoperatively underwent a lymphatic mapping and the SNB using Patent Blue. Results: The SLNs were found in 30 of 33 patients (90.9%), the SLN accurately predicted the status of the axillary in 29 (96.7%). In one case the SLN was negative, but other axillary nodes were tumor positive. Conclusion: This study confirmed that the procedure of lymphatic mapping and SNB in the patients with breast cancer is feasibility, and that the histological characteristics of the SLN accurately predict the status of the axillary node. We believe that this technique might replace axillary lymph node dissection for breast cancer patients with negative axillae in the future. 展开更多
关键词 Breast cancer Lymphatic mapping Sentinel node biopsy
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Current Role and Benefits of Sentinel Lymph Node Mapping in Endometrial Cancer 认领 引用 被引量：1
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作者 Shrestha Sugandha Yang Shen +1 位作者 Bajracharya Prayes Silwal Bal Mukunda 《Open Journal of Obstetrics and Gynecology》 2020年第4期478-492,共15页
Endometrial cancer (EC) is one of the three major malignant tumors of the female reproductive system in developed countries. In recent years, the incidence of EC ranks first in gynecological malignancy and the mainsta... Endometrial cancer (EC) is one of the three major malignant tumors of the female reproductive system in developed countries. In recent years, the incidence of EC ranks first in gynecological malignancy and the mainstay of treatment is Surgery. Although EC has a high prevalence, its several features associated with management are still unclear. Endometrial cancer lymph node status is the most important predictor of survival and also guides postoperative treatment planning but?in gynecologic oncology, lymphadenectomy, as a part of initial surgical management remains controversial. The current introduction of sentinel lymph node mapping in EC patients represents a midway between the execution and omission of node dissection. Sentinel lymph node (SLN) mapping has emerged as an alternative staging strategy hence, the role of SLN mapping is currently being evaluated prospectively in several centers. The objective of this review is to provide an update of the emerging role of sentinel node mapping in EC. In this review, we discussed how several different techniques, type of tracers utilized and injection sites has been described and used for lymphatic mapping in EC impacting on sentinel lymph node detection rates. In addition, we also discussed another evolving field in EC staging i.e.?interpretation of pathologic ultra staging of SLN, which can identify low volume metastasis for which the clinical significance and ideal management remain uncertain. Future perspective regarding EC management is also discussed in this review. 展开更多
关键词 Endometrial Cancer Sentinel Lymph Node Mapping Laparoscopy Robotic Surgery Ultrastaging
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Sentinel lymph node mapping for malignant melanoma of the external auditory canal 认领 引用
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作者 Joel Franco Lauren A Hansen +2 位作者 Richard T Miyamoto Mark Tann Michael G Moore 《World Journal of Surgical Procedures》 2015年第1期173-176,共4页
We describe a novel technique for sentinel lymph node mapping and biopsy of a primary cutaneous malignant melanoma in the medial portion of the external auditory canal. The approach is illustrated through a case repor... We describe a novel technique for sentinel lymph node mapping and biopsy of a primary cutaneous malignant melanoma in the medial portion of the external auditory canal. The approach is illustrated through a case report and technical description of a procedure performed under general anesthesia on a 19-year-old female patient. Due to the hidden and sensitive location of the primary tumor in the medial external auditory canal, the lymphoscintigraphy injection had to be performed by the surgeon immediately prior to the resection of her c T2 a N0M0 lesion. Final pathology revealed clear margins at the primary site resection and 2 intraparotid sentinel lymph nodes with microscopic foci of metastatic malignant melanoma, which led to further surgical management. A completion left parotidectomy and neck dissection yielded no additional metastatic disease in the fifty-five nodes that were evaluated. Using this technique, sentinel lymph node mapping and biopsy accurately predicted the highest risk lymph nodes for the primary lesion of the medial portion of the external auditory canal. 展开更多
关键词 Malignant melanoma External auditory canal Head and neck Sentinel lymph node biopsy Sentinel lymph node mapping
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Biologically Inspired Node Generation Algorithm for Path Planning of Hyper-redundant Manipulators Using Probabilistic Roadmap 认领 引用 被引量：2
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作者 Eric Lanteigne Amor Jnifene 《International Journal of Automation and computing》 CSCD 2014年第2期153-161,共9页
This article describes a biologically inspired node generator for the path planning of serially connected hyper-redundant manipulators using probabilistic roadmap planners. The generator searches the configuration spa... This article describes a biologically inspired node generator for the path planning of serially connected hyper-redundant manipulators using probabilistic roadmap planners. The generator searches the configuration space surrounding existing nodes in the roadmap and uses a combination of random and deterministic search methods that emulate the behaviour of octopus limbs. The strategy consists of randomly mutating the states of the links near the end-effector, and mutating the states of the links near the base of the robot toward the states of the goal configuration. When combined with the small tree probabilistic roadmap planner, the method was successfully used to solve the narrow passage motion planning problem of a 17 degree-of-freedom manipulator. 展开更多
关键词 Path planning hyper-redundant manipulators probabilistic road map(PRM) quasi-deterministic node generation bi-directional search algorithm.
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探讨定量DCE联合T1 mapping鉴别乳腺癌淋巴结转移的效能 认领 引用
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作者 陈琳 《黑龙江医药》 CAS 2023年第3期561-564,共4页
目的:探讨定量磁共振动态增强(DCE-MRI)联合纵向弛豫时间定量成像(T1 mapping)鉴别乳腺癌淋巴结转移的效能。方法:回顾性分析2021年12月—2022年9月在我院经病理证实为乳腺癌且行DCE-MRI及T1 mapping检查的70例患者的临床资料,评估定量... 目的:探讨定量磁共振动态增强(DCE-MRI)联合纵向弛豫时间定量成像(T1 mapping)鉴别乳腺癌淋巴结转移的效能。方法:回顾性分析2021年12月—2022年9月在我院经病理证实为乳腺癌且行DCE-MRI及T1 mapping检查的70例患者的临床资料,评估定量DCE联合T1 mapping参数鉴别乳腺癌淋巴结转移的价值。结果:单因素及多因素logistic分析结果显示EER、Tpeak、ADC、T1post、△T1%是评估乳腺癌淋巴结转移的独立参数(P0.70,且联合评估效能更好。结论:DCE-MRI联合T1 mapping检查的EER、Tpeak、ADC、T1post、△T1%参数具有较高的乳腺癌淋巴结转移评估效能,且上述参数联合评估的效能最佳。 展开更多
关键词 乳腺癌 淋巴结转移 DCE-MRI T1 mapping 诊断价值
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A Cross-Layer Optimization Framework for Energy Efficiency in Wireless Sensor Networks 认领 引用
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作者 Karuna Babber Rajneesh Randhawa 《Wireless Sensor Network》 2017年第6期189-203,共15页
We consider the extension of network lifetime of battery driven wireless sensor networks by splitting the sensing area into uniform clusters and implementing heterogeneous modulation schemes at different members of th... We consider the extension of network lifetime of battery driven wireless sensor networks by splitting the sensing area into uniform clusters and implementing heterogeneous modulation schemes at different members of the clusters. A cross-layer optimization has been proposed to reduce total energy expenditure of the network;at network layer, routing is done through uniform clusters;at MAC layer, each sensor node of the cluster is assigned fixed or variable time slots and at physical layer different member of the clusters is assigned different modulation techniques. MATLAB simulation proved substantial network lifetime gains. 展开更多
关键词 Clustering Cluster Heads Border Nodes Base Station Cross-Layer Design Physical Layer MAC Routing Layer Packet Size Modulation Quality of Services (QoS) Wireless Sensor Networks
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红麻始花节位QTL定位及候选基因分析 认领 引用
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作者 李辉 陈安国 +1 位作者 唐慧娟 栾明宝 《华北农学报》 CSCD 北大核心 2026年第3期75-81,共7页
为了探明红麻始花节位的遗传规律,以始花节位差异显著的红麻自交系K215和K89为亲本,构建了含有148个单株的F2群体。利用RAD-seq测序的方法进行bin标记基因分型,构建了红麻高密度遗传连锁图谱。该图谱含有3 418个bin标记且不均匀地分布... 为了探明红麻始花节位的遗传规律,以始花节位差异显著的红麻自交系K215和K89为亲本,构建了含有148个单株的F2群体。利用RAD-seq测序的方法进行bin标记基因分型,构建了红麻高密度遗传连锁图谱。该图谱含有3 418个bin标记且不均匀地分布在18条染色体上,图谱总遗传距离为864.61 c M,标记间平均遗传距离为0.25 cM。结合始花节位的表型数据和遗传图谱,利用区间作图法,检测到1个与始花节位密切相关的QTL位点FFN6。该位点位于第6号染色体,LOD值为8.66,表型贡献率为13.77%,加性效应值为-19.97。结果表明,该等位基因位点来自父本K215,对始花节位具有负调控作用。根据QTL定位区间内基因注释信息,初步筛选获得7个候选基因。qRT-PCR结果表明,短日照条件下Hc-bHLH6和Hc-MYB6基因的表达量显著增加,促进红麻植株开花,这2个候选基因可能与红麻植株始花节位密切相关。 展开更多
关键词 红麻 QTL 始花节位 遗传连锁图谱
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基于虚拟力鲸鱼算法的船舶无线传感器网络覆盖优化方法 认领 引用
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作者 尹震宇 李硕 +3 位作者 张飞青 徐光远 马雷乐 李东吉 《小型微型计算机系统》 CSCD 北大核心 2026年第3期737-742,共6页
在船舶制造环境中,无线信号容易受金属墙壁屏蔽和多路径效应影响,导致船舱内的无线传感器网络覆盖率下降,影响节点对环境信息的有效感知.为优化传感器节点部署以最大化网络覆盖率,本论文针对船舶制造环境中的无线传感器网络信号覆盖问题... 在船舶制造环境中,无线信号容易受金属墙壁屏蔽和多路径效应影响,导致船舱内的无线传感器网络覆盖率下降,影响节点对环境信息的有效感知.为优化传感器节点部署以最大化网络覆盖率,本论文针对船舶制造环境中的无线传感器网络信号覆盖问题,提出一种基于虚拟力鲸鱼融合算法的优化方法.首先,建立了考虑金属墙壁障碍的物节点感知模型,以适应船舱环境的复杂性.其次,在鲸鱼群智能优化算法基础上,融合了虚拟力算法,并引入无限折叠迭代混沌映射(Iterative Map with Infinite Collapses,ICMIC)以提高种群多样性,增强算法的全局搜索能力和局部寻优能力,从而有效解决覆盖优化问题.仿真实验结果表明,本文所提算法在船舱复杂环境下能够显著提高最优覆盖率,且算法收敛速度优于对比算法.本文为解决复杂船舶环境中的无线传感器网络覆盖问题提供了一种创新性方法,为相关领域的研究和应用提供了参考. 展开更多
关键词 无线传感器网络 覆盖优化 混沌映射 节点部署
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多策略协同的改进小龙虾优化算法及其工程应用 认领 引用
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作者 张晓丽 杨璨 +2 位作者 宋晶 朱贵富 聂佳磊 《小型微型计算机系统》 CSCD 北大核心 2026年第5期1156-1165,共10页
本文提出了一种多策略协同的改进小龙虾优化算法(ICOA),以解决原始COA算法多样性不足、收敛速度慢、易陷入局部最优等问题.首先,采用Logistic-Tent混沌映射替代随机初始化,提升初始解质量;其次,在迭代初期引入镜像反射学习机制,利用对... 本文提出了一种多策略协同的改进小龙虾优化算法(ICOA),以解决原始COA算法多样性不足、收敛速度慢、易陷入局部最优等问题.首先,采用Logistic-Tent混沌映射替代随机初始化,提升初始解质量;其次,在迭代初期引入镜像反射学习机制,利用对称性扩展解空间以加速收敛;此外,在避暑阶段融合透镜成像的自适应反向学习以增强算法跳出局部最优的能力;最后,结合遗传算法的垂直交叉操作,提高种群多样性以强化全局搜索能力.在实验部分,基于CEC2014测试函数,分别开展对比实验和消融实验验证算法性能的提升.研究证实,所提多策略协同机制有效克服了原始COA的缺陷,在收敛速度、精度和鲁棒性方面均有显著提升. 展开更多
关键词 小龙虾优化算法 混沌映射 镜像反射学习 自适应反向学习 随机节点交配的垂直交叉操作
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考虑节点功率和平均链路带宽的无线虚拟网络智能映射算法 认领 引用
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作者 张震 胡贵恒 盖昊宇 《兰州文理学院学报（自然科学版）》 2026年第1期50-55,共6页
针对无线虚拟网络智能映射常因资源分配不合理和映射效率低下,导致虚拟网络请求难以高效、合规地映射到物理网络的问题,提出一种考虑节点功率和平均链路带宽的无线虚拟网络智能映射算法.首先,计算物理网络和虚拟网络的节点功率资源和链... 针对无线虚拟网络智能映射常因资源分配不合理和映射效率低下,导致虚拟网络请求难以高效、合规地映射到物理网络的问题,提出一种考虑节点功率和平均链路带宽的无线虚拟网络智能映射算法.首先,计算物理网络和虚拟网络的节点功率资源和链路带宽资源,并设定其对应的约束条件;其次,按照可用资源将映射节点从高到低排列,同时找出虚拟网络的独立链路集;然后,在条件约束下,排除无效迭代计算过程,直接找出与虚拟节点对应的物理节点、与虚拟链路对应的物理链路,从而高效地完成无线虚拟网络的智能映射.实验结果表明,所提方法在物理网络平均收益和虚拟网络平均接受率方面表现良好,同时在虚拟网络消耗和链路映射平均跳数方面也有显著的优化效果. 展开更多
关键词 平均链路带宽 独立链路集 无线虚拟网络映射 权值系数 节点功率
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基于增强图卷积神经网络的机房环境运行状态识别方法 认领 引用
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作者 刘胜强 宋才华 《电子设计工程》 2026年第17期169-173,共5页
针对机房设备数量多、电磁干扰强、设备互联拓扑复杂带来的运行状态识别难点,该文提出一种基于增强图卷积神经网络的机房环境运行状态识别方法。该方法搭建机房环境拓扑图,采用量化采样抑制电磁干扰,借助Hermite变换提取节点时频特征,... 针对机房设备数量多、电磁干扰强、设备互联拓扑复杂带来的运行状态识别难点,该文提出一种基于增强图卷积神经网络的机房环境运行状态识别方法。该方法搭建机房环境拓扑图,采用量化采样抑制电磁干扰,借助Hermite变换提取节点时频特征,构造邻接矩阵完成图结构建模,将图数据输入增强图卷积网络实现节点特征聚合与运行状态概率求解,结合搭建的实验环境对该方法进行了验证实验。仿真测试结果表明,该文方法输出的机房运行状态概率曲线与真实工况曲线完全吻合,识别精度显著优于对比算法。 展开更多
关键词 机房环境图 增强图卷积神经网络 节点特征 运行状态识别 邻接矩阵
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NOTES:The question for minimal resection and sentinel node in early gastric cancer 认领 引用 被引量：5
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作者 Mitsuhiro Asakuma Ronan A Cahill +2 位作者 Sang-Woong Lee Eiji Nomura Nobuhiko Tanigawa 《World Journal of Gastrointestinal Surgery》 2010年第6期203-206,共4页
Surgical therapy for gastric cancer involves both removal of the cancer lesion and complete lymph node dissection.Natural orifice transluminal endoscopic surgery(NOTES) is considered to represent the next revolution i... Surgical therapy for gastric cancer involves both removal of the cancer lesion and complete lymph node dissection.Natural orifice transluminal endoscopic surgery(NOTES) is considered to represent the next revolution in surgery.Many surgeons and endoscopists believe that NOTES may be a superior alternative for early gastric cancer treatment.Sentinel node(SN) navigation surgery for gastric cancer:Single institution results of SN mapping for early gastric cancer are increasingly being considered acceptable.Furthermore,a major large-scale clinical trial of SN mapping for gastric cancer has recently been completed by The Japan Society of SN Navigation Surgery study group.They reported false negative rate of 7.0 while the sensitivity of metastasis detection based on SN status was 93.Combination of SN biopsy and NOTES:This concept was first described by Cahill et al who proved the feasibility of lymphatic mapping and SN biopsy by NOTES.Lymphatic channel filling was immediately observable via the intraperitoneal optics.Partial resection of the stomach by hybrid NOTES:Several centers have already reported gastrectomy assisted by NOTES using the transvaginal route.However,the main problem of full-thickness resection of gastric wall remains endoscopic gastric closure.Establishing an endoscopic suturing method would be an important step toward expanding potential indications.NOTES is met with both enthusiasm and skepticism but will gain its own place as human creativity eventually provides solutions to its technical limitations.In the near future,NOTES can evolve the capacity to complement the existing armamentarium for gastric cancer surgery. 展开更多
关键词 Early gastric cancer Lymphatic mapping Endoscopic submucosal dissection Sentinel node biopsy Natural orifice transluminal endoscopic surgery
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双能CT定量新指标对于胰腺癌淋巴结转移的诊断能力评估 认领 引用
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作者 何成青 谢飞扬 +6 位作者 陈新月 高鑫 成思航 常晓燕 丛福泽 钱滢先 薛华丹 《放射学实践》 CAS CSCD 北大核心 2026年第6期639-647,共9页
目的:探讨双能CT(DECT)定量参数标准化碘浓度(NIC)、淋巴结报告与数据系统(Node-RADS)以及影像组学在术前预测胰腺导管腺癌(PDAC)淋巴结转移(LNM)的价值。方法:回顾性纳入97例接受术前DECT检查的PDAC患者。通过将影像与术后病理淋巴结... 目的:探讨双能CT(DECT)定量参数标准化碘浓度(NIC)、淋巴结报告与数据系统(Node-RADS)以及影像组学在术前预测胰腺导管腺癌(PDAC)淋巴结转移(LNM)的价值。方法:回顾性纳入97例接受术前DECT检查的PDAC患者。通过将影像与术后病理淋巴结分区对齐,评估NIC、Node-RADS及影像组学特征对LNM的预测效能。采用多因素Logistic回归构建NIC与Node-RADS的影像联合模型。基于支持向量机(SVM)构建纯影像组学模型,并与临床预测因子(pN+比例)融合,建立临床-影像组学联合模型。所有影像组学相关模型均在独立测试集中进行验证。结果:较低的NIC值与较高的Node-RADS评分是LNM的独立预测因素(P<0.05)。NIC与Node-RADS的影像联合模型曲线下面积(AUC)为0.668。基于虚拟单能图像(VMI)的临床-影像组学联合模型在测试集中达到了近乎完美的判别性能,AUC为0.976,诊断准确度为95.6%(95%CI:0.85~0.99),敏感度为95.0%(95%CI:0.75~0.99),特异度为96.0%(95%CI:0.80~0.99)。决策曲线分析进一步证实,临床-影像组学联合模型在临床相关阈值范围(0.1~0.6)内能提供持续的正向净获益,显示出明确的临床实用性。结论:DECT定量参数、Node-RADS评分与影像组学特征均是预测PDAC淋巴结转移的有效工具。临床-影像组学联合模型表现出卓越的诊断性能,有望为胰腺癌的术前精准分期提供强有力的影像学生物标志物。 展开更多
关键词 胰腺癌 双能CT 碘图 标准化碘浓度 影像组学 淋巴结报告与数据系统 淋巴结转移
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基于MDS-MAP和非线性滤波的WSN定位算法 认领 引用 被引量：16
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作者 陈岁生 卢建刚 楼晓春 《浙江大学学报（工学版）》 EI CAS CSCD 北大核心 2012年第5期866-872,共7页
为提高传感器网络节点的定位精度,对MDS-MAP结合非线性滤波方法的多种传感器网络定位算法进行研究.根据传感器节点间距离与节点定位坐标之间存在的非线性关系,在MDS-MAP定位算法的基础上,引入扩展卡尔曼滤波(EKF)求精算法和不敏卡尔曼滤... 为提高传感器网络节点的定位精度,对MDS-MAP结合非线性滤波方法的多种传感器网络定位算法进行研究.根据传感器节点间距离与节点定位坐标之间存在的非线性关系,在MDS-MAP定位算法的基础上,引入扩展卡尔曼滤波(EKF)求精算法和不敏卡尔曼滤波(UKF)求精算法,对MDS-MAP求得的节点坐标进行求精.对MDS-MAP定位算法、MDS-MAP和EKF相结合的定位算法(MDS-EKF)、MDS-MAP和UKF相结合的定位算法(MDS-UKF)的定位精度进行比较.实验结果表明:EKF和UKF等非线性滤波方法的应用可以提高定位精度,在相同条件下MDS-UKF定位算法的定位精度更高并且其生成的网络拓扑图最接近于实际网络拓扑图. 展开更多
关键词 节点自定位 MDS-MAP 扩展卡尔曼滤波 不敏卡尔曼滤波
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基于混沌映射改进蝙蝠优化的DV-Hop定位算法 认领 引用
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作者 董玉 张治中 冯姣 《计算机与数字工程》 2026年第3期589-594,606,共6页
针对DV-Hop算法定位精度低的问题,提出基于混沌映射改进蝙蝠优化的DV-Hop定位算法(ICEMBADV-Hop)。该算法主要在求解平均跳距和估计节点位置两方面进行优化。首先,依据最小均方误差准则重新求解平均跳距并设置修正因子以减小测距误差;其... 针对DV-Hop算法定位精度低的问题,提出基于混沌映射改进蝙蝠优化的DV-Hop定位算法(ICEMBADV-Hop)。该算法主要在求解平均跳距和估计节点位置两方面进行优化。首先,依据最小均方误差准则重新求解平均跳距并设置修正因子以减小测距误差;其次,利用logistic混沌映射改变种群分布,增加种群多样性,采取两种全新的位置更新策略,增强全局搜索能力,制定局部搜索策略,并设置参数因子控制搜索的范围,提升搜寻的精度。最后,采用混沌映射改进蝙蝠算法(CEMBA)求解未知节点的坐标。仿真结果表明,设置相同的参数,不论在各向同性网络还是各向异性网络中,相比DV-Hop算法、MDV-Hop算法、BADV-Hop算法、PSODV-Hop算法,提出的ICEMBADV-Hop算法均具有最小的定位误差,定位性能优越。 展开更多
关键词 无线传感器网络 节点定位 蝙蝠算法 DV-Hop算法 混沌映射
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亚甲蓝与纳米碳在乳腺癌患者腋窝逆向淋巴示踪中的应用效果 认领 引用
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作者 张毅 安仲军 +1 位作者 王博 宋利 《临床误诊误治》 CAS 2026年第5期61-66,共6页
目的比较亚甲蓝与纳米碳在乳腺癌患者腋窝逆向淋巴示踪(ARM)中的应用效果。方法选取2021年2月至2024年7月收治的80例行ARM及腋窝淋巴结清扫术的女性乳腺癌患者,采用随机信封法分为亚甲蓝组和纳米碳组各40例,亚甲蓝组以亚甲蓝为示踪剂,... 目的比较亚甲蓝与纳米碳在乳腺癌患者腋窝逆向淋巴示踪(ARM)中的应用效果。方法选取2021年2月至2024年7月收治的80例行ARM及腋窝淋巴结清扫术的女性乳腺癌患者,采用随机信封法分为亚甲蓝组和纳米碳组各40例,亚甲蓝组以亚甲蓝为示踪剂,纳米碳组以纳米碳为示踪剂。比较两组腋窝淋巴结染色情况、淋巴结检出情况、淋巴结转移诊断结果(腋窝淋巴结转移率以及ARM检查的敏感度、假阴性率、准确率)、手术指征及并发症发生情况。结果纳米碳组染色成功率为97.50%(39/40),高于亚甲蓝组的80.00%(32/40,P0.05)。纳米碳组微小淋巴结检出数多于亚甲蓝组(P0.05)。纳米碳组术中寻找腋窝淋巴结所用时间、染色时间短于亚甲蓝组,而褪色时间长于亚甲蓝组(P0.05)。两组并发症总发生率比较无统计学差异(P>0.05)。结论亚甲蓝与纳米碳作为ARM示踪剂,二者在乳腺癌患者淋巴结转移诊断中的应用价值相近。而相较于亚甲蓝,纳米碳的淋巴结染色成功率及微小淋巴结检出率更高,其术中腋窝淋巴结寻找时间及染色时间更短,褪色时间更长,但成本相对更高,临床可根据患者意愿及病情选取合适的示踪剂。 展开更多
关键词 乳腺癌 亚甲蓝 纳米碳 腋窝淋巴结 逆向淋巴示踪 淋巴结转移 诊断 并发症
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基于四节点单侧映射逆壳单元的薄壁结构位移场识别 认领 引用
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作者 黄铭欣 王风翔 +1 位作者 赵振宇 孙良晖 《船舶工程》 CSCD 北大核心 2026年第2期119-128,共10页
[目的]为解决海工薄壁结构(如海上风机塔筒)在复杂动态载荷下强度评估的需求,以及克服传统逆有限元法(iFEM)依赖结构内外壁同步应变监测的工程限制等问题,[方法]提出一种新型四节点单侧映射逆有限元方法(iFEM_S)。该方法构建于壳单元的... [目的]为解决海工薄壁结构(如海上风机塔筒)在复杂动态载荷下强度评估的需求,以及克服传统逆有限元法(iFEM)依赖结构内外壁同步应变监测的工程限制等问题,[方法]提出一种新型四节点单侧映射逆有限元方法(iFEM_S)。该方法构建于壳单元的单侧泛函分析模型基础之上,仅需获取结构内壁的应变信息,即可实现节点位移场的精确求解。[结果]数值仿真验证表明,相较于传统iFEM,iFEM_S方法显著减少了50%的传感器配置数量,同时提升了位移场重建的精度。为增强该数学模型的鲁棒性,系统分析了9种不同测点布局方案对iFEM_S位移场重构精度及抗干扰性能的影响。[结论]对比结果确定,在单个四节点逆壳单元的左下角布置测点为最优方案。当监测信号的信噪比(SNR)达到20 dB时,采用此优化方案,位移场最大重构误差可控制在1%以内。 展开更多
关键词 薄壁结构 位移场重构 逆有限元法 单面映射 四节点逆壳单元
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