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Impact of seasonal hydrological changes on the small-strain shear modulus of undisturbed and remolded highly expansive soils 认领 引用
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作者 Chuanyong Xu Lingwei Kong +3 位作者 Tianguo Li Zhenhua Zhou Junbiao Yan Zhaowei Shang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第5期3868-3881,共14页
In the natural environment,the soil structure can be weakened by temperature fluctuations and climatic changes.Nevertheless,the dynamic behavior of expansive soils,especially those with high swelling and pronounced fi... In the natural environment,the soil structure can be weakened by temperature fluctuations and climatic changes.Nevertheless,the dynamic behavior of expansive soils,especially those with high swelling and pronounced fissure properties,subjected to wetting-drying-freeze-thaw(WDFT)cycles has been rarely investigated.Undisturbed and remolded samples,made of Xinjiang’s highly expansive soils,were evaluated in this study through comprehensive resonant column tests conducted at several confining pressures and WDFT cycles.A typical hyperbolic model demonstrated the decay law of shear modulus with strain.An estimated model of the maximum shear modulus,incorporating the two factors,was developed,and it was found to be in good agreement with the measurement results.The results reveal that strain,WDFT cycle,and confining pressure have qualitatively uniform effects on the shear modulus of natural soils containing fissures and recompacted samples.However,the maximum shear modulus of the undisturbed samples is lower by 0.83–13.24 MPa due to the presence of initial fissures,except for the confining pressure of 400 kPa.Also,their responses to confining pressure are more significant,with the shear modulus increased by up to 20%–124%relative to that at 25 kPa.Furthermore,the relative difference in the shear modulus(up to about 60%)between the two samples tested under low confining pressure conditions deserves special attentions.The quantitative differences in shear modulus and cumulative damage effect of the tested samples are attributed to the initial fabric and microstructural evolution,as observed by Scanning Electron Microscope(SEM).This research enriches the theoretical framework for analyzing the ability of soils to resist shear deformation under small strain,which is instructive for disaster prevention and mitigation in expansive soil regions,considering the effects of climate change. 展开更多
关键词 Highly expansive soil Shear modulus Wetting-drying-freeze-thaw cycles Fissure evolution Resonant column
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High-precision calculations of highly excited and autoionizing states of the nickel atom 认领 引用
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作者 Sheng-Bo Niu Jun-Yao Zhang +1 位作者 Rui Jin Yi-Zhi Qu 《Chinese Physics B》 SCIE EI CAS CSCD 2026年第6期469-477,共9页
High-precision atomic data,including highly excited energy levels and their lifetimes,as well as autoionizing states,are essential for astrophysics,materials science,and energy research applications.Despite the increa... High-precision atomic data,including highly excited energy levels and their lifetimes,as well as autoionizing states,are essential for astrophysics,materials science,and energy research applications.Despite the increasing demand for highprecision databases,the availability of data concerning complex transition-metal atoms remains limited.In this work,we present a systematic high-precision theoretical study of highly excited and autoionizing states of the nickel atom for Jπ=4-symmetry,considering the indispensable correlation effects between bound and continuum configurations.Calculations for discrete highly excited states and autoionizing states are conducted under the same theoretical scheme,which employs the relativistic multichannel theory(RMCT),to obtain an eigenchannel scattering matrix that varies smoothly over a wide energy region.The scattering matrix is then used with the multichannel quantum defect theory(MQDT)to semi-analytically obtain highly excited states and autoionizing states.Excellent agreement is achieved between the theoretical results and existing experimental discrete levels with a maximum of 0.02%deviation.An abnormal lifetime variation of the autoionizing states along the same series is observed.The resonance energy,lifetime,and assignment of autoionizing states are systematically presented for the first time,with the objective of contributing to the fields of astrophysics,materials science,and energy research.The datasets presented in this paper,including the energy levels and lifetimes of autoionizing states,are openly available at http://gffzzd3cc09b8251d45dfsc5xpn9wbqxqf65xo.ffgz.tsg.suse.edu.cn/10.57760/sciencedb.j00113.00279. 展开更多
关键词 multichannel quantum defect theory highly excited states autoionizing states high precision
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Migration of Brown-headed Gulls on the Qinghai-Tibet Plateau:Potential transmission routes for highly pathogenic H5Nx virus 认领 引用
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作者 Mengdan Fei Yi Li +10 位作者 Shunmeng Qu Xinru Lv Chuanxiu Li Xuyang Zhao Yang Xiu Qing An Guofeng Zhang Xiang Li Siyuan Yang Linhong Xie Hongliang Chai 《Avian Research》 SCIE CAS CSCD 2026年第3期714-722,共9页
The Qinghai-Tibet Plateau serves as a critical hub along the Central Asian Flyway(CAF)and a recognized hotspot for the emergence of highly pathogenic avian influenza(HPAI)viruses.Despite recurrent outbreaks,the migrat... The Qinghai-Tibet Plateau serves as a critical hub along the Central Asian Flyway(CAF)and a recognized hotspot for the emergence of highly pathogenic avian influenza(HPAI)viruses.Despite recurrent outbreaks,the migratory dynamics of key reservoir species,such as the Brown-headed Gull(Chroicocephalus brunnicephalus)and their potential contributions to viral dissemination remain poorly understood.Here,we integrated highresolution GPS telemetry with Bayesian discrete phylogeographic analyses to investigate the potential association between migration and HPAI H5Nx dissemination.Based on tracking data from 11 individuals,we identified 5 major life-history stages and 12 important stopover sites used during migration,including 6 in autumn and 6 in spring,and characterized their spatiotemporal distribution patterns.Phylogenetic reconstruction showed that three independent introductions of HPAI H5Nx viruses occurred on the Qinghai-Tibet Plateau between 2021 and 2024,all involving strains associated with Brown-headed Gulls and classified into the 2021-H5N8Ⅰ,2021-H5N8Ⅱ,and 2022-H5N1 clusters.These viral clusters were distributed primarily along the CAF and the East Asian–Australasian Flyway(EAAF),with diffusion patterns broadly consistent with the spatiotemporal dynamics of migratory birds.Notably,the spread of the 2022-H5N1 cluster along the CAF was highly concordant with the migratory route and phenology of Brown-headed Gulls,while host transition analysis suggested that gulls may serve as bridging hosts in interspecies transmission.Together,these findings suggest that Brown-headed Gulls may contribute to the cross-regional dissemination and interspecies transmission of HPAI H5Nx viruses,and highlight the value of combining tracking data with viral genomics for cross-border surveillance. 展开更多
关键词 Annual cycle Gulls Highly pathogenic avian influenza Migratory birds Satellite tracking Viral transmission
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Study of the effect of nanoemulsion on the EOR in low-permeability,highly waxy oil reservoirs based on NMR displacement experiments 认领 引用
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作者 Rui-Jie Fei Ming-Hui Li +5 位作者 Shuai Yuan Chen Cao Fu-Jian Zhou Er-Dong Yao Hao Bai Diu-Wei Ding 《Petroleum Science》 SCIE EI CAS CSCD 2026年第2期897-912,共16页
Wax precipitation damage caused by cold water injection or temperature reduction is very commonly seen in the development of waxy crude oil reservoirs.Various methods for eliminating wax precipitation damage have been... Wax precipitation damage caused by cold water injection or temperature reduction is very commonly seen in the development of waxy crude oil reservoirs.Various methods for eliminating wax precipitation damage have been studied by many scholars,such as injecting hot water,artificial fracture,and using chemical dewaxing agents.However,the effects of nanoemulsion on wax crystals and enhanced oil recovery(EOR)have not yet been systematically studied.This study used core displacement system based on nuclear magnetic resonance(NMR)to investigate the effect of nanoemulsion on the EOR in low-permeability,waxy oil reservoirs.Some influencing factors such as injection water temperatures,core permeability,fractured/unfractured core,and nanoemulsion concentration conditions have been investigated.Meanwhile,the wax crystal morphology and quantity have been studied before and after using nanoemulsion using a polarizing microscope.The main conclusions are as follows:(1)After injecting 60℃hot water,the recovery can be increased from 19.36%to 32.82%,which can alleviate wax deposition damage to a certain extent.(2)Enhancing core permeability or using fractured cores can increase the flow capacity of displacement fluid within the core and enhance waxy crude oil recovery.The EOR after improving core permeability is 10.22%,while the EOR of the fractured core is 26.24%.(3)Nanoemulsions can dissolve wax crystals in waxy crude oil and inhibit their formation to achieve EOR.The crude oil recovery at nanoemulsion concentrations of 0.1,0.5,and 1.0 wt%were 34.84%,38.24%,and 42.85%,respectively.(4)The use of nanoemulsion can reduce the number,area ratio,and fractal dimension of wax crystals,thereby mitigating wax deposition damage.Using a 1 wt%of nanoemulsion,the area ratio of wax crystals decreased from 47.25%to 16.67%,and the number of wax crystals decreased from 1309 to 496. 展开更多
关键词 EOR of highly waxy oil reservoir Wax deposition damage Nanoemulsion NMR
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Active learning for global optimization of highly non-stationary geotechnical engineering systems using Bayesian compressive sensing 认领 引用
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作者 Peiping Li Yin-Fu Jin +1 位作者 Lei Wang Xiangsheng Chen 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第7期5324-5341,共18页
Global optimization constitutes a crucial challenge in design optimization in geotechnical engineering,which aims to maximize the performance objective function of a geotechnical engineering system,thereby achieving t... Global optimization constitutes a crucial challenge in design optimization in geotechnical engineering,which aims to maximize the performance objective function of a geotechnical engineering system,thereby achieving the optimal output.For complex geotechnical engineering systems with computationally time-consuming models and highly non-stationary responses,the direct application of stochastic optimization algorithms usually requires numerous evaluations of the original model,resulting in significantcomputational expense.To tackle this challenge,this study develops an innovative and efficientglobal optimization(EGO)method using Bayesian compressive sensing(BCS)and active learning for highly non-stationary geotechnical engineering problems,referred to as BCS-based EGO.In BCS-based EGO,BCS is utilized to train a response surface from a training sample set,enabling the efficientexecution of the stochastic optimization algorithm and providing response predictions along with the associated uncertainty at each search point.The response surface results are combined with an active learning sampling criterion to adaptively identify additional optimal sampling points,updating the response surface and training sample set to enhance the accuracy of response prediction and global optimization,until the stopping criterion of active learning is satisfied.The proposed method is capable of handling highly non-stationary data because BCS is data-driven and non-parametric.Moreover,it efficientlyaddresses the challenge of underestimating the factor of safety and failure probability in limit equilibrium method-based slope stability and reliability analysis using the potential slip surface method.Investigations utilizing three highly non-stationary benchmark examples and two highly nonstationary engineering examples indicate that BCS-based EGO performs well with sparse sampling points. 展开更多
关键词 Efficientglobal optimization(EGO) Highly non-stationary data Bayesian compressive sensing(BCS) Active learning Slope reliability analysis
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Entropy-Controlled Exsolution of Highly Dispersed Nickel-Based Active Metals From Spinel Oxide via Optimizing Metal-Support Interaction for Dry Reforming of Methane 认领 引用 被引量:1
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作者 Yuxuan Meng Yuefan Tuo +8 位作者 Yao Xue Xiaofeng Yan Zhengkun Luo Qianrui Yang Stanislav Chernyshikhin Yilong Yan Meng Lin Yufei Zhao Xianguang Meng 《Carbon Energy》 SCIE EI CAS CSCD 2026年第2期132-143,共12页
Sintering and coking are critical barriers to achieving high performance in dry reforming of methane(DRM)catalysts.A finely dispersed and thermostable Ni-based catalyst is the key to address these issues.By leveraging... Sintering and coking are critical barriers to achieving high performance in dry reforming of methane(DRM)catalysts.A finely dispersed and thermostable Ni-based catalyst is the key to address these issues.By leveraging the intrinsic superiorities of high-entropy oxides in high-temperature stability and low atomic diffusivity,in this study,a highly dispersed Ni-based catalyst is synthesized via an entropycontrolled exsolution of active components.By increasing the number of transition-metal elements in spinel oxides,the active metalsupport interaction(MSI)can be continuously strengthened,which controls the exsolution and thermal stability of Ni-based active metal in harsh reaction conditions of DRM.An optimized medium-entropy spinel(Mg0.4Ni0.2Co0.2Zn0.2)Al2O4with the exsolution of finely dispersed Ni–Co nanoparticles displayed superior activity and stability in thermal DRM at 800°C and photothermal DRM.This entropy-controlled MSI and exsolution principle provides a significant strategy for designing robust catalysts resistant to sintering and coking for high-temperature reactions like DRM in thermal and photothermal systems. 展开更多
关键词 dry reforming of methane exsolution high‐entropy N icatalyst spinel
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SW-DWNS:A Single-Wave Autonomous Navigation System in Partially Observable,Highly Dynamic Warehouses 认领 引用
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作者 Xianhui Fan Zongwei Li +1 位作者 Yuxuan Zhai Zhenyu Li 《Computers, Materials & Continua》 SCIE EI 2026年第9期1758-1773,共16页
Single-wave order picking in dynamic warehouses is a sequential multi-goal navigation problem.A robot must visit an ordered set of shelves and then a delivery station while avoiding moving obstacles under partial obse... Single-wave order picking in dynamic warehouses is a sequential multi-goal navigation problem.A robot must visit an ordered set of shelves and then a delivery station while avoiding moving obstacles under partial observability.Existing approaches either entangle long-horizon task logic with low-level obstacle avoidance or rely on static-environment assumptions that limit responsiveness in dynamic settings.This paper proposes the Single-Wave Dynamic Warehouse Navigation System(SW-DWNS),a lightweight scheduling framework that extends a pretrained ColorDynamic point-to-point local planner to ordered warehouse picking without retraining.The scheduler maintains a shelf queue,exposes only the active subgoal to the local policy,and advances the queue through an arrival-gated state machine with a geometrically derived pickup threshold.We evaluate SW-DWNS in a controlled dynamic warehouse simulation benchmark with three layouts,pickup horizons K∈{1,…,5},stochastic obstacle motion,sensor noise,and obstacle-size randomization.Across the full layout-horizon grid,SW-DWNS achieves 87.3%average success,compared with 26.8%for A*search combined with the Dynamic Window Approach(A*+DWA)and 1.3%for ColorDynamic only.The gain is not obtained by sacrificing safety:the average collision rate is reduced from 69.0%for A*+DWA to 7.5%for SW-DWNS.Factor-wise ablation shows uneven robustness across disturbances:sensing noise and obstacle-size randomization have limited impact(main effects of+1 and+4.5 percentage points),whereas disabling obstacle motion costs 33 percentage points and shifts failures from collision to timeout.A pickup-threshold sweep further shows that reported success rates become inflated outside the admissible geometric bandε∈[14,31]cm.These results show that a decoupled scheduling layer can make a pretrained dynamic local planner effective for sequential warehouse picking,while also revealing the conditions under which that extension remains valid. 展开更多
关键词 Warehouse robot single-wave order picking navigation under partial observability highly dynamic environment autonomous navigation system
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Olanzapine-based vs neurokinin-1 receptor antagonist antiemetic regimens in highly emetogenic chemotherapy:Systematic review and meta-analysis of efficacy and safety 认领 引用
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作者 Advaitha Mv Nikhilesh Anand +7 位作者 Uttam Udayan Jacqueline Mendoza Alissa Lopez Bharathi S Gadad Biacin Babu Ayoola Awosika Brahmaiahchari Rangachari Sabyasachi Maity 《World Journal of Clinical Cases》 2026年第12期27-40,共14页
studies were included in the systematic review with 11 meeting the criteria for meta-analysis.Primary outcomes were complete response(no vomiting,no rescue medication)and nausea control during acute(0-24 hours),delaye... studies were included in the systematic review with 11 meeting the criteria for meta-analysis.Primary outcomes were complete response(no vomiting,no rescue medication)and nausea control during acute(0-24 hours),delayed(25-120 hours),and overall(0-120 hours)phases.Data were pooled using random-effects models.Risk of bias was assessed with Cochrane risks of bias 2.0 and risk of bias in nonrandomized studies of interventions version I tools.RESULTS Olanzapine-based regimens showed higher nausea control,with no-nausea rates of 89%vs 76%(P95%).CONCLUSION Olanzapine-based regimens are at least as effective as neurokinin-1 antagonist therapy for chemotherapy-induced nausea and vomiting in HEC,particularly for delayed nausea.Low-dose(5 mg)olanzapine provides effective,well-tolerated,oral,and cost-efficient prophylaxis,supporting its use as a first-line antiemetic. 展开更多
关键词 Carboplatin Cisplatin Highly emetogenic chemotherapy Neurokinin-1 antagonist Olanzapine
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Plasma metabolites-based drug design:Discovery of novel and highly selective phosphodiesterase 5 inhibitors 认领 引用
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作者 Deyan Wu Qingjiang Ma +9 位作者 Yanquan Chen Guofeng Yang Fengcai Zhang Meiyan Jiang Xue Wang Xingfu Liu Qian Zhou Yi-You Huang Zhe Li Hai-Bin Luo 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第5期402-407,共6页
In drug discovery,it is extremely important to identify highly potent leads with desirable drug-like profiles.Almost all the marketed phosphodiesterase 5(PDE5)inhibitors such as sildenafil,vardenafil,and tadalafil hav... In drug discovery,it is extremely important to identify highly potent leads with desirable drug-like profiles.Almost all the marketed phosphodiesterase 5(PDE5)inhibitors such as sildenafil,vardenafil,and tadalafil have poor selectivity over PDE6 or PDE11 and leading to several side effects.Herein,a metabolites-based scaffold hopping strategy was performed to discover selective PDE5 inhibitors with remarkable metabolic stability.The Eu(OTf)3-catalyzed Mannich-type reaction followed by L-selectride catalyzed reduction was used to prepare chiral 2,3,3a,4,5,6-hexahydro-1H-benzo[b]pyrido[2,3,4-de][1,6]naphthyridines as novel PDE5 inhibitors with high enantioselectivity(>99%ee and>30:1 dr).Lead L9exhibited a half maximal inhibitory concentration(IC50)of 1.03 nmol/L with higher selectivity(>898-fold)over PDE6 or PDE11 than sildenafil and tadalafil,implying the potential relief from side effects.Especially,the co-crystal binding pattern of L9 with PDE5 is revealed to be different from that of sildenafil,which possibly explain the former’s high selectivity.And oral administration of L9·HCl(5.0 mg/kg)exhibited better therapeutic effects than pirfenidone(150 mg/kg)in a bleomycin-induced idiopathic pulmonary fibrosis(IPF)rat model,highlighting the potential of L9·HCl for the treatment of IPF. 展开更多
关键词 Drug discovery Scaffold hopping High selectivity Phosphodiesterase 5 inhibitors Idiopathic pulmonary fibrosis
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Association between choroidal thickness and primary open angle glaucoma in highly myopic eyes 认领 引用
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作者 Pei-Yao Jin Min Tang +6 位作者 Min-Wen Zhou Ying Fan Yu-Ye Ling Jian-Feng Zhu Hai-Dong Zou Jiang-Nan He Wen-Wen Xue 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第6期1088-1095,共8页
AIM:To investigate the relationship between choroidal thickness(CT)and primary open angle glaucoma(POAG)in highly myopic eyes across different categories of myopic atrophic maculopathy(MAM).METHODS:This observational ... AIM:To investigate the relationship between choroidal thickness(CT)and primary open angle glaucoma(POAG)in highly myopic eyes across different categories of myopic atrophic maculopathy(MAM).METHODS:This observational analytical case–control study enrolled highly myopic patients.All participants underwent comprehensive ophthalmic examinations.CT was measured in peripapillary and macular regions using optical coherence tomography(OCT).Each eye was classified for POAG status and MAM category.Stepwise logistic regression was performed to identify factors independently associated with POAG.RESULTS:Among 248 highly myopic subjects,37(18 males,mean age 68.25±7.16y)had POAG(25 bilateral,12 unilateral)and 211(97 males,mean age 67.09±7.63y)were non-glaucomatous.Age and sex did not differ significantly between groups(both P>0.05).Seventy-eight patients had unilateral high myopia and 170 bilateral,yielding 418 highly myopic eyes,of which 58(13.88%)had POAG.POAG prevalence across MAM categories(no lesion to complete macular atrophy)was 7.14%,16.28%,14.07%,17.86%,and 17.14%,respectively(P=0.44).In the diffuse chorioretinal atrophy subgroup,POAG eyes showed significantly thicker CT in central,inner nasal,outer superior,inner superior,and inner inferior macular regions,and thinner central corneal thickness(all P<0.05).Stepwise logistic regression showed that only parafoveal inferior CT was independently associated with POAG in this subgroup(OR=1.017;95%CI:1.005–1.028;P<0.01).No significant CT–POAG association was found in other MAM categories.CONCLUSION:Increased macular CT is independently associated with POAG in highly myopic eyes with diffuse chorioretinal atrophy.This implies distinct pathogenic mechanisms underlying POAG development across different MAM categories in high myopia. 展开更多
关键词 glaucoma primary open angle glaucoma choroidal thickness high myopia myopic atrophic maculopathy
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Highly durable Volmer-Heyrovsky hydrogen evolution reaction in alkaline media 认领 引用
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作者 Yuandong Yan Qian Zheng +2 位作者 Yuxiang Yan Shicheng Yan Zhigang Zou 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第2期177-185,I0006,共9页
Reducing high overpotentials in the alkaline water reduction reaction is critical for renewable hydrogen storage.Here,we report a dual-site catalytic center comprising oxygen-bridging Fe-OH and Ni-O(FeOHO-NiO)with ... Reducing high overpotentials in the alkaline water reduction reaction is critical for renewable hydrogen storage.Here,we report a dual-site catalytic center comprising oxygen-bridging Fe-OH and Ni-O(FeOHO-NiO)with Pt-like activity,where frustrated Fe-OH Lewis acid and Ni-O Lewis base generate a strong electrostatic field to promote water dissociation(Volmer step:H2O+e-→Had*+OH-).The resulting Had*adsorbs on Ni-O,forming Ni-OHad,while Fe-OH and Ni-OHad synergistically drive the Heyrovsky step(Had*+H2O+e-*H2+OH-)to produce H2.This process achieves ultralow overpotential(52 mV@10 mA cm-2)and exceptional stability(>1000 h@300 mA cm-2),offering a design strategy for low-cost and high-performance hydrogen evolution reaction catalysts. 展开更多
关键词 FeOH–O–NiO Volmer-Heyrovsky reaction H2O activation Electrocatalytic hydrogen High durability
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JPA Highly Cited Papers and Hot Papers in 2025 认领 引用
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《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2026年第3期I0001-I0003,共3页
A review on the screening methods for the discovery of natural antimicrobial peptides Bin Yang,Hongyan Yang,Jianlong Liang,Jiarou Chen,Chunhua Wang,Yuanyuan Wang,Jincai Wang,Wenhui Luo,Tao Deng,Jialiang Guo J.Pharm.An... A review on the screening methods for the discovery of natural antimicrobial peptides Bin Yang,Hongyan Yang,Jianlong Liang,Jiarou Chen,Chunhua Wang,Yuanyuan Wang,Jincai Wang,Wenhui Luo,Tao Deng,Jialiang Guo J.Pharm.Anal.202515(1)101046 http://gffzzd3cc09b8251d45dfsc5xpn9wbqxqf65xo.ffgz.tsg.suse.edu.cn/10.1016/j.jpha.2024.101046.Coupling of an Au@AgPt nanozyme array with an micrococcal nuclease-specific responsiveness strategy for colorimetric/SERS sensing of Staphylococcus aureus in patients with sepsis. 展开更多
关键词 JPA hot papers au agpt nanozyme array screening methods highly cited papers antimicrobial peptides natural antimicrobial peptides staphylococcus aureus
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Characterization of novel highly pathogenic avian influenza A(H5N6)clade 2.3.4.4b virus in wild birds,East China,2024 认领 引用 被引量:1
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作者 Renjie Sun Xiaoxiao Feng +9 位作者 Jing Huang Fangyu Zheng Ronghui Xie Chuanliang Zhang Hongli Zhang Yin Xue Aijun Liu Xiaobing Huang Lin Yuan Lingyan Zhao 《Virologica Sinica》 SCIE CAS CSCD 2025年第2期284-287,共4页
Dear Editor,The highly pathogenic avian influenza viruses(HPAIVs)are important epizootic and zoonotic pathogens that cause significant economic losses to the poultry industry and pose a serious risk to veterinary and ... Dear Editor,The highly pathogenic avian influenza viruses(HPAIVs)are important epizootic and zoonotic pathogens that cause significant economic losses to the poultry industry and pose a serious risk to veterinary and public health.Wild birds have been recognized as the primary reservoirs for influenza A virus,and some species show little sign of clinical disease or even can be asymptomatic during long distance carriers of the virus(Lycett et al.,2019).Since it was first discovered in 1959,the H5Nx HPAIVs have spread globally and cause outbreaks in wild birds,poultry and sporadic human and other mammalian infections(Lycett et al.,2019).Due to the reassortant events of diverse strains facilitated by migratory waterfowl,the clade 2.3.4.4 of H5Nx viruses acquiring neuraminidase(NA)gene from other low pathogenicity avian influenza viruses(LPAIVs)emerged in 2014 and gradually became the dominant sub-clade(Lee et al.,2017). 展开更多
关键词 wild birds highly pathogenic avian influenza East China epizootic highly pathogenic avian influenza viruses hpaivs avian influenza H N zoonotic h nx hpaivs
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Synergistic SnSe2@Ti3C2Tx MXene Heterostructured Separator for Highly Efficient Polysulfide Adsorption,Catalytic Redox Acceleration,and Enhanced Electrochemical Stability in Advanced Lithium-Sulfur Batteries 认领 引用 被引量:1
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作者 Amirhossein Mirtaleb Matija Scekic Ruigang Wang 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2026年第2期264-280,共17页
Lithium-sulfur(Li-S)batteries hold tremendous promise for next-generation energy storage due to their high theoretical energy density and low cost.However,commercialization is hindered by severe polysulfide shuttling,... Lithium-sulfur(Li-S)batteries hold tremendous promise for next-generation energy storage due to their high theoretical energy density and low cost.However,commercialization is hindered by severe polysulfide shuttling,sluggish redox kinetics,and rapid capacity decay under practical loading conditions.Herein,we report a rationally engineered SnSe2@Ti3C2Tx MXene heterostructure as a multifunctional separator coating that synergistically combines strong Lewis acidic adsorption sites with catalytic interfaces and a highly conductive,polar-terminated MXene matrix.The SnSe2 nanosheets provide abundant catalytic centers to accelerate the redox conversion of soluble Li2Sx species,while Ti3C2Tx ensures rapid electron transport and robust chemical immobilization of polysulfide intermediates.This interfacial synergy effectively suppresses the shuttle effect,lowers electrochemical polarization,and promotes rapid charge transfer.Electrochemical evaluations reveal an initial discharge capacity of 1626 mAh g-1at 0.2 C with nearly 100%Coulombic efficiency.Under high sulfur loading(5 mg cm-2)and lean-electrolyte conditions(E/S=6μL mg-1),cells with the SnSe2@MXene-coated separator deliver 751 mAh g-1after 120 cycles,retaining 70.9%of their initial capacity.Remarkably,long-term cycling at 1 C exceeds 1000 cycles with 44.4%capacity retention and minimal structural degradation.This work demonstrates a scalable,effective separator-engineering strategy,establishing SnSe2@MXene as a promising platform for practical,high-energy-density Li-S batteries. 展开更多
关键词 cycling stability high sulfur loading lithium–sulfur batteries polysulfide shuttle effect SnSe2@MXene heterostructure
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Mesh‑Architected Structurally Flexible Pb(Zr0.52Ti0.48)O3 Framework Enables Highly Sensitive and Stretchable Piezoelectric Sensors 认领 引用
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作者 Li Zeng Chenhui Jiang +4 位作者 Yuan Li Hao Yin Qichao Li Hezhou Liu Yiping Guo 《Nano-Micro Letters》 SCIE EI CAS CSCD 2026年第8期893-908,共16页
The booming demand for flexible electronics requires piezoelectric sensors that can simultaneously deliver high sensitivity and exceptional stretchability,which has become a significant challenge beyond the capabiliti... The booming demand for flexible electronics requires piezoelectric sensors that can simultaneously deliver high sensitivity and exceptional stretchability,which has become a significant challenge beyond the capabilities of conventional devices.Inspired by the hexagonal mesh structure,we adopted an architecture design to fabricate a continuous,structurally flexible ceramic skeleton,thereby developing a piezoelectric sensor integrating both high sensitivity and superior stretchability.The macroscopic 3D interconnected skeleton ensures efficient stress transfer for enhanced pressure sensitivity,while the hexagonal topology with hierarchical microfibers enables deformation-driven slippage under load to ensure robust stretchability.Consequently,the composite achieves remarkable stretchability(220%strain)and excellent mechanical stability(>50 stretch-compression cycles,hysteresis~8.13%).The fully flexible piezoelectric sensor maintains stable functionality even under 100%tensile strain and exhibits high sensitivity(39.57 mV kPa−1),collectively outperforming conventional piezoelectric sensors.Based on these unique advantages,we demonstrate the sensor’s capability in fine surface roughness discrimination and real-time monitoring of human stretching movements,highlighting its great potential for applications in robotic dexterous manipulation and wearable health monitoring systems. 展开更多
关键词 Piezoelectric sensor Structurally flexible High sensitivity High stretchability Mesh architecture
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Occurrence and intake risk assessment of high production volume chemicals in highly consumed seafood species 认领 引用
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作者 Sílvia Borrull Francesc Borrull +1 位作者 Rosa M.Marcé Eva Pocurull 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第3期718-728,共11页
High production volume chemicals(HPVCs)found in the environment and fish may pose health risks through dietary intake.This study measured the levels of 30 HPVCs in the ten most consumed fish species in Spain over one ... High production volume chemicals(HPVCs)found in the environment and fish may pose health risks through dietary intake.This study measured the levels of 30 HPVCs in the ten most consumed fish species in Spain over one year.The compounds with the highest average concentrations were di-(2-ethylhexyl)phthalate(740.8 ng/g dw(dry weight)),di-(2-ethylhexyl)-adipate(675.8 ng/g dw),and galaxolidone(579.0 ng/g dw).The highest intake values were recorded in Atlantic tuna,with 51.0 ng/(kg bw·day)in the high-consumption scenario.Noncarcinogenic risks were greatest for benzosulfonamides,particularly in sardine and Atlantic tuna.Carcinogenic risk factors were highest for Atlantic mackerel and tuna but remained below European Food Safety Authority safety limits,suggesting low concern for public health.Long-term monitoring provided a more accurate estimate of dietary exposure and associated health risks. 展开更多
关键词 atlantic tunawith dietary intake noncarcinogenic risks high production volume chemicals carcinogenic risks health risks high production volume chemicals hpvcs found seafood
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Highly sensitive,ultra-low detection limit 3-D DNA nanostructure biosensor based on functionalized reflective optical fiber probe 认领 引用
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作者 Yufang Chen Wenbo Zhao +5 位作者 Jinxing Xiong Jiashu Zhang Kai Zhang Jiale Xie Menghan Liu Hongdan Wan 《Chinese Physics B》 SCIE EI CAS CSCD 2026年第5期454-463,共10页
A highly sensitive,ultra-low detection limit 3-D DNA nanostructure biosensor based on functionalized reflective optical fiber probe(ROFP)is proposed and demonstrated.Our approach achieves a mass limit of detection of~... A highly sensitive,ultra-low detection limit 3-D DNA nanostructure biosensor based on functionalized reflective optical fiber probe(ROFP)is proposed and demonstrated.Our approach achieves a mass limit of detection of~10 aM based on the ROFP.A particular single-nucleotide mismatch sequence is also identified.The sensitivity of the proposed DNA biosensor is 1.51 nm/lgaM,about three-fold higher than using single-strand DNA probes(0.47 nm/lgaM)and with high specificity.The proposed ROFP has high compactness(with a length of~3 mm)which is convenient for sample detection with small volume and complex gradients in small spaces with high sensitivity. 展开更多
关键词 DNA biosensor ultra-low detection limit high sensitivity reflective optical fiber probe secondary interference 3-D DNA nanostructure
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Breaking Concentration Quenching for Excellent Highly Efficient and Stable Narrowband Luminescence by Structural Ordering and Defect Regulation 认领 引用
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作者 Yuhan Zhou Ruijie Ji +1 位作者 Zhezhe Su Yuhua Wang 《Rare Metals》 SCIE EI CAS CSCD 2026年第2期657-668,共12页
Enhancing the performance of phosphor materials for wide-color-gamut and high-brightness phosphor-converted light-emitting diodes (pc-LEDs) represents a critical materials challenge.Improving quantum efficiency (QE) u... Enhancing the performance of phosphor materials for wide-color-gamut and high-brightness phosphor-converted light-emitting diodes (pc-LEDs) represents a critical materials challenge.Improving quantum efficiency (QE) under concentration quenching constraints and maintaining thermal stability remain primary objectives.Here,we propose a nitrogen-aluminosilicate host,La1-xSi9Al19N32(L1-xASN):x Eu2+(0.1≤x≤1.0),with a highly condensed network.Through cationic ordering and optimized local crystal field configurations under ultrahigh activator doping (x=1.0),we achieved enhanced structural rigidity that effectively suppresses nonradiative energy transfer.This strategy resulted in external quantum efficiency (EQE) increases of 332% for the x=1.0 sample relative to the x=0.5 sample,the optimal doping concentration.The high structural rigidity and artificially created nitrogen vacancy defect compensate for emission loss during the thermal generation process,improving thermal stability at x=1.0 by 278% compared to x=0.5.The designed phosphor enables pc-LEDs with a wide color gamut(106.6%NTSC) and ultrahigh brightness (8.56×106cd m-2).This study advances the understanding of the relationship between luminescent properties and microstructure,demonstrating the effectiveness of structural ordering and defect engineering in enhancing the performance of LED phosphors. 展开更多
关键词 cationic ordering defect engineering high pressure luminescence LED structural rigidity
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Dense solid electrolyte interphase and Zn(002)plane texture enabling high depth-of-discharge anode for highly reversible zinc ion batteries 认领 引用
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作者 Haojie Ji Yuhang Liang +9 位作者 Tao Yang Hongbo Wu Ouwei Sheng Tianyu Shen Chang Dong Tan Du Li Yin Jian Zhang Rongkun Zheng Xuefeng Zhang 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2026年第1期56-64,共9页
Aqueous zinc-ion batteries(AZIBs)hold promising prospects for large-scale energy storage systems,yet their commercialization is hindered by dendritic growth and water-induced side reactions associated with zinc anodes... Aqueous zinc-ion batteries(AZIBs)hold promising prospects for large-scale energy storage systems,yet their commercialization is hindered by dendritic growth and water-induced side reactions associated with zinc anodes,especially at high depths of discharge(DOD).Herein,a multifunctional zincophilic additive is developed to promote the planar Zn deposition and construct a stable solid electrolyte interphase(SEI).Disodium malate(DMA)possesses pH-buffering capability that maintains electrolyte pH stability during prolonged cycling,effectively mitigating side reactions.Furthermore,the concentration of DMA significantly influences crystal deposition.An appropriate amount of DMA molecules selectively adsorbs onto the zinc foil,facilitating uniform zinc ion deposition on the(002)crystal plane.In addition,disodium maleate molecules reconfigure the electric double layer(EDL)to reduce free water interaction and promote the in-situ formation of the dense SEI,consisting of inorganic zinc salt and amorphous organic component,on the Zn metal surface.Notably,the dense organic-inorganic hybrid SEI layer persists with remarkable structural integrity even after long cycling.These features enable a highly reversible dendritefree Zn plating/stripping process and suppress side reactions.As a result,Zn||Zn cells with DMA additives demonstrate extended cycling stability,enduring up to 5000 h at 8.6%DOD.Moreover,DMA-modified Zn anodes achieve an exceptional cycle lifespan of 750 h under 81.9%DOD with a high coulombic efficiency of 99.81%in asymmetric cells.In full-cell configurations,Zn||I2 cells stably cycle for over 12,000 cycles,retaining 89.77%of their capacity.This electrolyte regulation strategy offers a compelling pathway for the development of aqueous zinc ion batteries. 展开更多
关键词 Aqueous zinc ion batteries Zn anode Solid electrolyte interphase High depth-of discharge Plane texture
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Visual and anatomic outcomes of epiretinal membrane surgery in highly myopic eyes with varying axial lengths 认领 引用
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作者 Xiao-Han Yang Xiao Feng +3 位作者 Bi-Ying Qi Xi-Jin Wu Qin-Lang Jia Wu Liu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第6期1117-1123,共7页
AIM:To observe the clinical features and the surgical outcomes of the high myopic(HM)patients with epiretinal membranes(ERM).METHODS:This was a retrospective study enrolled HM patients diagnosed with ERM who underwent... AIM:To observe the clinical features and the surgical outcomes of the high myopic(HM)patients with epiretinal membranes(ERM).METHODS:This was a retrospective study enrolled HM patients diagnosed with ERM who underwent vitrectomy between May 2012 and November 2021.Three groups were divided according to axial length(AXL):26–<28 mm(n=43),28–<30 mm(n=22),and≥30 mm(n=11).Baseline characteristics and postoperative visual and anatomical outcomes were analyzed.RESULTS:Totally 76 consecutive eyes of 73 HM patients(27 males),with a mean age of 60.5±9.2y(range:38–84y)were enrolled.The initial best-corrected visual acuity(BCVA)of the three groups was not significantly different(P=0.498).Longer AXL was associated with a higher incidence of both inner and outer macular retinoschisis(MRS),ellipsoid zone(EZ)disruption,and foveal retinal detachment(all P<0.05).Only the eyes in the 26–<28 mm group showed a significant improvement in postoperative BCVA.BCVA was improved in 77.6%of the eyes.Among the eyes with BCVA not improved,58.8%belonged to the group 26–<28 mm.The postoperative macular hole was seen in 1(1.32%)eye.Multivariate linear regression analysis indicated that initial BCVA(P<0.001)and epiretinal proliferation(P=0.010)influenced the final BCVA.CONCLUSION:AXL is not significantly associated with visual recovery.Early operative intervention might have better visual and anatomical outcomes in HM-ERM patients. 展开更多
关键词 high myopia epiretinal membrane axial length pars plana vitrectomy visual acuity
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