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Assessment of Hunters and Other Rate of Illegal Activities in Afi-Mbe-Okwango Division, Cross River State, Nigeria 认领 引用
1
作者 Sodienye Augustine Abere Funmilayo Lewiska Lateef Gbolagade Akeem Lameed 《Natural Resources》 2016年第5期287-294,共8页
Bushmeat hunting is one of the greatest pressure to wildlife alongside habitat fragmentation, deforestation, land use change and climate change. Despite the interventions from government and Non Governmental Organizat... Bushmeat hunting is one of the greatest pressure to wildlife alongside habitat fragmentation, deforestation, land use change and climate change. Despite the interventions from government and Non Governmental Organization to reduce or divert the attention of rural people from the wild by providing alternative livelihood, the level of hunting either remains the same or kept on increasing. However, there is need to categorize and understand the types of hunters in different locality for better design and management of whatever alternative to be provided. The study assessed hunters’ types and their income made from hunting in Afi, Mbe and the Okwango Division of the National park and the rate of poaching activities. The snowball sampling was adopted for gathering data. A descriptive and inferential statistical tool was used to analyze the data collected. The respondents were interviewed with a view to obtaining information on the regularity of their hunting activities, the income made per month and reasons why they hunt and also their views on best alternative. Results revealed that majority of the respondent fall within the age of less than or equal to 40 years with primary and secondary school qualification in which are married with 3 - 12 children. Consequent to this fact hunting activities is effective and prevailing. It further revealed that despite numerous conservation efforts in these areas, poaching activities still prevail owing to the fact that the income made from poaching is much better than the alternative provided for hunters. Furthermore, the assessment also revealed that there are different types of hunters and this makes their income varies greatly. Thus, there are fulltime or core hunters (36.9%), occasional hunters (58.3%), Holiday hunters (2.9%) and social hunters (1.9%). It is therefore paramount to have a better view and understanding of the target group (Poachers) for better alternative and implementation. 展开更多
关键词 Hunters Income Poaching Afi-Mbe-Okwango Division
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Spell Chanting Hunters in Jiarong 认领 引用
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作者 GARBODA 《China's Tibet》 EI 2000年第1期40-40,共1页
关键词 Spell Chanting Hunters in Jiarong
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Hunters Try to Capture Their Past 认领 引用
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《The Journal of Human Rights》 2012年第1期14-16,共3页
Mo Guizhen was 5 when she saw a real bed for the first time. She refused to ,sleep on it, accustomed asshe was to deer furs laid on the ground of hunters＇ huts in the depths of the Greater Hinggan Mountains in north-... Mo Guizhen was 5 when she saw a real bed for the first time. She refused to ,sleep on it, accustomed asshe was to deer furs laid on the ground of hunters＇ huts in the depths of the Greater Hinggan Mountains in north- eastern China. 展开更多
关键词 Hunters Try to Capture Their Past
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Primitive Mammoth Hunters and the Earliest Breed of Dog 认领 引用
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作者 Petr N. Kolosov 《Natural Resources》 2014年第3期99-105,共7页
Primitive man have managed to survive in the rigorous climatic conditions of the arctic regions in northeast Asia owing to the hunting for mammoth, bison, wooly rhinoceros and other Pleistocene mammals with the assist... Primitive man have managed to survive in the rigorous climatic conditions of the arctic regions in northeast Asia owing to the hunting for mammoth, bison, wooly rhinoceros and other Pleistocene mammals with the assistance of the laika, a domesticated wolf. This is how the colonization of the Arctic began. The domestic dog appeared in this region about 25 - 30 thousand years ago as a result of the severe climatic conditions in which both hunting tribes and the ancestors of the domestic dog had to live. A wolf is a predator, an able hunter. Therefore, most likely wolves were originally trained to hunt with humans—the leaders of the hunting pack. Thus, in northeast Asia, there was a direct relationship between man’s colonization of the Arctic, the appearance of the hunting dog, and a decrease in the number of mammoth, bison, and other large animals in the region, as a result of hunting when whole herds were killed. 展开更多
关键词 Asia Arctic Paleolithic Mammoth Primitive Hunter Wolf Domestication Dog
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虎鲸与海豚联手捕食 认领 引用
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作者 宋鹭 《疯狂英语（新悦读）》 2026年第3期47-49,78,共3页
主题群:动物行为研究篇幅:312词建议用时:6分钟.1 For the first time,researchers have documented killer whales and Pacific white-sided dolphins cooperating to hunt salmon off the coast of British Columbia.This never-befor... 主题群:动物行为研究篇幅:312词建议用时:6分钟.1 For the first time,researchers have documented killer whales and Pacific white-sided dolphins cooperating to hunt salmon off the coast of British Columbia.This never-before-seen behavior,recorded on video,challenges previous understandings of interactions between these marine hunters and suggests a strategic and mutually beneficial partnership. 展开更多
关键词 marine hunters killer whales Cooperation Pacific White sided Dolphins Strategic Partnership Salmon Mutual Benefit
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全新疗法带来希望 认领 引用
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作者 李成 《疯狂英语（新悦读）》 2026年第4期65-66,79,80,共2页
In Manchester,England,a three-year-old boy from the US has become the first person in the world to successfully receive a special treatment for a rare health condition called Hunter Syndrome.Hunter Syndrome is caused ... In Manchester,England,a three-year-old boy from the US has become the first person in the world to successfully receive a special treatment for a rare health condition called Hunter Syndrome.Hunter Syndrome is caused by a gene in the body that doesn't work correctly(genes contain the instructions on how a person will develop and grow).This prevents the body from being able to keep some of its cells healthy,causing delays in development in young children.This condition can become very serious. 展开更多
关键词 hunter syndromehunter syndrome genetic disorder development delay new therapy gene function hunter syndrome cell health
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Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago 认领 引用
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作者 Ruairidh Macleod 《四川生理科学杂志》 2026年第7期1571-1571,共1页
Plague is among the most devastating diseases in human history1.However,early strains of the plague-causing bacterium Yersinia pestis lacked virulence factors that are required for the bubonic form until around 3,800 ... Plague is among the most devastating diseases in human history1.However,early strains of the plague-causing bacterium Yersinia pestis lacked virulence factors that are required for the bubonic form until around 3,800 years ago2,3.Consequently,the morbidity and mortality of early plague strains remain unclear.Here we describe early plague strains that are associated with two phases of outbreaks among mid-Holocene hunter-gatherers near Lake Baikal in southeast Siberia,beginning from about 5,500 years ago.These outbreaks occur across four hunter-gatherer cemeteries,with a 39%detection rate for plague infection.By reconstructing kinship pedigrees,we show that small familial groups were affected,consistent with human-to-human spread of disease,and that the first outbreak occurred within a single generation.The infections appear to have resulted in acute mortality,especially among children(aged 8 to 11 years).We further note functional differences,including in the ypm superantigen locus,which is also present in present day Yersinia pseudotuberculosis.The new strains diverge ancestrally to known Y.pestis and constrain the timing of its emergence,indicating that this happened before approximately 5,700 years ago.These findings show that plague outbreaks happened earlier than previously thought and were indeed lethal.We contend that the occurrence of outbreaks among mid-Holocene hunter-gatherer communities well outside the sphere of Late Neolithic Europe challenges the notion that higher population densities and lifestyle changes during the Neolithic agricultural transition were prerequisites for plague epidemics. 展开更多
关键词 yersinia pestis Lake Baikal outbreaks plague virulence factors bubonic form hunter gatherers mid Holocene
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Montana Duck Hunters 认领 引用
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作者 王雷 《中学生数学（高中版）》 2007年第11期
Ten Montana hunters are in a duck blind when 10 ducks fly over.All 10 hunters pick a duck at random to shoot at,and all 10 hunters fire at the same time.How many ducks could be expected to escape,on average。
关键词 Montana Duck Hunters
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FOSSIL HUNTERS 认领 引用
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作者 TANG YUANKAI 《Beijing Review》 2006年第41期20-23,共4页
关键词 FOSSIL HUNTERS
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Hepatitis E virus in professionally exposed: A reason for concern? 认领 引用 被引量：2
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作者 Anna Mrzljak Ivan Balen +2 位作者 Ljubo Barbic Maja Ilic Tatjana Vilibic-Cavlek 《World Journal of Hepatology》 2021年第7期723-730,共8页
The zoonotic risk of hepatitis E virus(HEV)is well established.The HEV seroprevalence rates vary according to geographical region,assays used,and study cohorts.HEV infection is still underdiagnosed,implying the need t... The zoonotic risk of hepatitis E virus(HEV)is well established.The HEV seroprevalence rates vary according to geographical region,assays used,and study cohorts.HEV infection is still underdiagnosed,implying the need to evaluate the disease's burden in the general population and specific risk groups,such as professionally exposed.Close contact with various animal reservoirs such as pigs,rabbits,sheep,dogs,wild boars,and deer has been associated with higher anti-HEV seroprevalence as a part of occupational exposure.While exact transmission routes remain to be determined,some general preventive measures such as proper hand hygiene,the usage of personal protective equipment,and the thermal processing of food before consumption should be followed.A“One-Health”multisectoral approach should be implemented to achieve optimal health and well-being outcomes,recognizing the interconnections between humans,animals,plants,and their shared environment,in which a vaccine against the zoonotic genotypes 3 and 4 and swine vaccination should be considered as a possible public health measure.This opinion review comprehensively addresses the HEV burden of professional exposure for butchers,slaughterhouse workers,veterinarians,farmers,hunters,and forestry workers delineates the current limits of protective work measures,and tackles future directions. 展开更多
关键词 Hepatitis E virus Zoonotic infection Occupational disease Veterinarians Farmers Butchers Slaughterhouse workers Forestry workers Hunters
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荣耀MagicBook Pro 162025 HUNTER评测:轻薄本与游戏本的“全能进化” 认领 引用
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《计算机应用文摘》 2025年第24期259-261,共3页
在游戏本市场,“性能”与“便携”似乎是矛盾的。传统游戏本为了追逐极致性能,往往不得不妥协于厚重的机身,而轻薄本则在图形性能上难以满足3A大作的需求。然而,2025年随着英特尔全新一代酷睿Ultra 200H系列处理器的到来,以及NVIDIA GeF... 在游戏本市场,“性能”与“便携”似乎是矛盾的。传统游戏本为了追逐极致性能,往往不得不妥协于厚重的机身,而轻薄本则在图形性能上难以满足3A大作的需求。然而,2025年随着英特尔全新一代酷睿Ultra 200H系列处理器的到来,以及NVIDIA GeForce RTX 50系列笔记本电脑GPU的更新,荣耀推出了全新的MagicBook Pro 162025 HUNTER游戏本。 展开更多
关键词 游戏本 MagicBook Pro 162025 HUNTER
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3种颜色体系在食品应用中的研究进展 认领 引用 被引量：31
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作者 雷用东 邓小蓉 +2 位作者 罗瑞峰 魏向利 罗小玲 《食品科学》 EI CAS CSCD 北大核心 2016年第1期241-246,共6页
外观颜色是食品的一个重要属性,影响着人们对食品质量的感知。用于描述食品颜色且适于测量颜色差异的Hunter Lab体系、国际照明委员会(Commission International de IEclairage,CIE)LAB体系和CIELCH体系,已被广泛应用于食品工厂的颜色... 外观颜色是食品的一个重要属性,影响着人们对食品质量的感知。用于描述食品颜色且适于测量颜色差异的Hunter Lab体系、国际照明委员会(Commission International de IEclairage,CIE)LAB体系和CIELCH体系,已被广泛应用于食品工厂的颜色测量中。本文综述了国内外Hunter Lab、CIELAB和CIELCH体系应用于食品颜色研究中的现状,对3种颜色体系的特性、3种体系在各类食品颜色研究中的最新进展进行了阐述,并对未来3种颜色体系应用的发展方向进行展望,以期为食品颜色研究应用提供参考。 展开更多
关键词 颜色体系 CIELAB Hunter Lab CIELCH 食品
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金属钛生产工艺研究进展 认领 引用 被引量：34
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作者 王志 袁章福 郭占成 《过程工程学报》 EI CAS 北大核心 2004年第1期90-96,共7页
介绍了制备金属钛的传统方法:Kroll法、Hunter法及熔盐电解法的工艺原理和概况,同时介绍了在这些方法的基础上正在开发和改进的钛制备方法,包括导电体介入还原法、连续生产钛粉的Armstrong法和直接电化学还原TiO2的FFC剑桥工艺,分析了... 介绍了制备金属钛的传统方法:Kroll法、Hunter法及熔盐电解法的工艺原理和概况,同时介绍了在这些方法的基础上正在开发和改进的钛制备方法,包括导电体介入还原法、连续生产钛粉的Armstrong法和直接电化学还原TiO2的FFC剑桥工艺,分析了各种方法的机理及特点. 由此指出降低钛生产成本的新工艺发展方向是转变现有间歇的海绵钛生产工艺为连续的金属钛粉及其合金的生产工艺. 展开更多
关键词 炼钛 提取冶金 生产工艺 Kroll法 Hunter法 熔盐电解
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扫描仪在棉纤维颜色检测的适用性 认领 引用 被引量：7
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作者 衡冲 沈华 +1 位作者 陈丽君 王府梅 《东华大学学报（自然科学版）》 CAS 北大核心 2020年第1期29-34,共6页
根据颜色光学理论,建立了现有棉纤维颜色分级指标(反射率R d和黄色深度+b)的换算方程。使用扫描仪获取12种棉纤维的颜色信息,分析了扫描仪明度对测色的影响,对比了扫描仪与HVI(high volume instrument)系统测试的R d、+b值。结果表明,... 根据颜色光学理论,建立了现有棉纤维颜色分级指标(反射率R d和黄色深度+b)的换算方程。使用扫描仪获取12种棉纤维的颜色信息,分析了扫描仪明度对测色的影响,对比了扫描仪与HVI(high volume instrument)系统测试的R d、+b值。结果表明,两者测得的R d值具有高度一致性,+b值也存在较高的线性正相关性。在棉纤维颜色分级的Hunter色空间中,多种棉纤维的颜色分级指标a值(红绿色)存在明显差异,表明该颜色分级指标不容忽略。因此,可通过数码测色技术测试R d、a和+b指标以对棉纤维的颜色进行科学、准确、低成本的测试评价。 展开更多
关键词 棉纤维 颜色分级 Hunter色空间 扫描仪 HVI系统
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Genetic Analysis of 17 Children with Hunter Syndrome:Identification and Functional Characterization of Four Novel Mutations in the Iduronate-2-Sulfatase Gene 认领 引用 被引量：2
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作者 Dimitry A.Chistiakov Lyudmila M.Kuzenkova +8 位作者 Kirill V.Savost’anov Anait K.Gevorkyan Alexander A.Pushkov Alexey G.Nikitin Nato D.Vashakmadze Natalia V.Zhurkova Tatiana V.Podkletnova Leila S.Namazova-Baranova Alexander A.Baranove 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2014年第4期197-203,共7页
Mucopolysaccharidosis type II （MPS II） is a rare X-linked disorder caused by alterations in the iduronate-2-sulfatase （IDS） gene. In this study, IDS activity in peripheral mononuclear blood monocytes （PMBCs） was... Mucopolysaccharidosis type II （MPS II） is a rare X-linked disorder caused by alterations in the iduronate-2-sulfatase （IDS） gene. In this study, IDS activity in peripheral mononuclear blood monocytes （PMBCs） was measured with a fluorimetric enzyme assay. Urinary glycosaminoglycans （GAGs） were quantified using a colorimetric assay. All IDS exons and intronic flanks were bidirectionally sequenced. A total of 15 mutations （all exonic region） were found in 17 MPS II patients. In this cohort of MPS II patients, all alterations in the IDS gene were caused by point nucleotide substitutions or small deletions. Mutations p.Arg88His and p.Arg172＊ occurred twice. All mu- tations were inherited except for p.Gly489Alafs＊7, a germline mutation. We found four new mutations （p.Ser142Phe, p.Arg233Gly, p.Glu430＊, and p.Ile360Tyrfs＊31）. In Epstein-Barr virus （EBV）-immortalized PMBCs derived from the MPS II patients, no IDS protein was detected in case of the p.Ser142Phe and p.Ile360Tyrfs＊31 mutants. For p.Arg233Gly and p.Glu430＊, we observed a residual expression of IDS. The p.Arg233Gly and p.Glu430＊ mutants had a residuary enzymatic activity that was lowered by 14.3 and 76-fold, respectively, compared with healthy controls. This observation may help explain the mild disease phenotype in MPS II patients who had these two mutations whereas the p.Ser142Phe and p.Ile360Tyrfs＊31 mutations caused the severe disease manifestation. 展开更多
关键词 Hunter syndrome Mucopolysaccharidosis type II Iduronate-2-sulfatase Mutations Glycosaminoglycans
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Molecular survey of tick-borne pathogens in Ixodid ticks collected from hunted wild animals in Tuscany, Italy 认领 引用
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作者 Valentina Virginia Ebani Fabrizio Bertelloni +2 位作者 Barbara Turchi Dario Filogari Domenico Cerri 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2015年第9期702-705,共4页
Objective: To determine the prevalence of zoonotic tick-borne bacteria in feeding ticks removed from hunted wild animals. Methods: PCR was executed on DNA extracted from 77 tick pools to detect Anaplasma phagocytophil... Objective: To determine the prevalence of zoonotic tick-borne bacteria in feeding ticks removed from hunted wild animals. Methods: PCR was executed on DNA extracted from 77 tick pools to detect Anaplasma phagocytophilum, Bartonella spp., Borrelia burgdorferi sensu lato, Coxiella burnetii and Rickettsia spp. Results: A total of 432 ticks were collected: 30(6.94%) Haemaphysalis punctata, 72(16.7%) Dermacentor marginatus and 330(76.38%) Ixodes ricinus. For each animal one or two pools of 3 ticks of the same species was constituted. Seventy-seven tick pools were examined by PCR: 58(75.32%) resulted infected and among them 14(18.18%) showed co-infections. In particular, 29(37.66%) pools were positive for Bartonella spp., 23(29.87%) for Anaplasma phagocytophilum, 16(20.78%) for Rickettsia spp., and 5(6.49%) for Borrelia burgdorferi s.l. All samples were negative for Coxiella burnetii. Conclusions: The results demonstrate the presence of several zoonotic tick-borne pathogens in the studied area, and underline the risk of exposure to infections for hunters not only during the outdoor activity, but also when they manipulate hunted animals infested by infected ticks. 展开更多
关键词 Ixodid ticks Tick-borne bacteria Wild animals PCR Hunters
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A new mutation (1062 del 16) of iduronate-2-sulfatase gene from a Chinese patient with Hunter syndrome 认领 引用 被引量：4
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作者 GUO Yi-bin PAN Jing-xin MENG Ya-xian 《Journal of Zhejiang University-SCIENCE B》 EI CAS 2007年第8期566-569,共4页
Objective: To identify the mutations of iduronate-2-sulfatase (IDS) gene, to reveal its mutation features, and to establish a basis for genetic counseling and prenatal gene diagnosis of Hunter syndrome. Methods: Urine... Objective: To identify the mutations of iduronate-2-sulfatase (IDS) gene, to reveal its mutation features, and to establish a basis for genetic counseling and prenatal gene diagnosis of Hunter syndrome. Methods: Urine glycosaminoglycans (GAGs) assay, PCR and DNA sequencing were performed to detect mutation of IDS gene of the patient and his parents. Results: The result showed that the patient was: DS(++), HS(++), KS(-), CS(-), and that both of his parents were negative. A frame-shift deletion mutation (1062 del 16) was identified in exon 7 of the patient's IDS gene. His parents' genotypes were normal. Conclusion:The patient's mutation was not inherited by his parents but a novel one. The mutation probably altered the primary structure and tertiary structure of IDS enzyme protein remarkably and lowered the activity of IDS enzyme greatly. Therefore it is supposed to be the direct cause of the disorder. 展开更多
关键词 Hunter syndrome Mucopolysaccharidosis typeⅡ （MPSⅡ） Glycosaminoglycan （GAG） Iduronate-2-sulfatase （IDS） Mutation Gene diagnosis DNA sequencing
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Insights into hepatitis E virus epidemiology in Croatia 认领 引用
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作者 Pavle Jelicic Thomas Ferenc +12 位作者 Anna Mrzljak Lorena Jemersic Natasa Janev-Holcer Milan Milosevic Maja Bogdanic Ljubo Barbic Branko Kolaric Vladimir Stevanovic Mateja Vujica Zeljka Jurekovic Jadranka Pavicic Saric Maja Vilibic Tatjana Vilibic-Cavlek 《World Journal of Gastroenterology》 SCIE CAS 2022年第37期5494-5505,共12页
BACKGROUND Hepatitis E virus(HEV)is an emerging virus of global health concern.The seroprevalence rates differ greatly according to geographic region and population group.AIM To analyze the seroprevalence of HEV in ex... BACKGROUND Hepatitis E virus(HEV)is an emerging virus of global health concern.The seroprevalence rates differ greatly according to geographic region and population group.AIM To analyze the seroprevalence of HEV in exposed(animal-related professions)and nonexposed populations,as well as solid organ and hematopoietic stem cell transplant patients.METHODS Forestry workers(n=93),hunters(n=74),and veterinarians(n=151)represented the exposed population.The general population(n=126)and pregnant women(n=118)constituted the control group.Transplant patients included liver transplant recipients(LTRs)(n=83),kidney transplant recipients(KTRs)(n=43),and hematopoietic stem cell transplant recipients(HSCRs)(n=39).HEV immunoglobulin G antibodies were detected using the enzyme-linked immunosorbent assay and confirmed by the immunoblot test.RESULTS The HEV seroprevalence significantly differed between groups:Veterinarians 15.2%,hunters 14.9%,forestry workers 6.5%,general population 7.1%,and pregnant women 1.7%.In transplant patients,the seropositivity was highest in LTRs(19.3%),while in KTRs and HSCRs,the seroprevalence was similar to the general population(6.9%and 5.1%,respectively).A significant increase in seropositivity with age was observed from 2.9%in individuals less than 30 years to 23.5%in those older than 60 years.Sociodemographic characteristics(sex,educational level,area of residence,and number of household members),eating habits(game meat,offal,and pork products consumption),and environmental and housing conditions(drinking water supply,type of water drainage/sewer,waste disposal,domestic animals)were not associated with HEV seropositivity.However,individuals who reported a pet ownership were more often seropositive compared to those who did not have pet animals(12.5%vs 7.0%).CONCLUSION The results of this study showed that individuals in professional contact with animals and LTRs are at higher risk for HEV infection.In addition,age is a significant risk factor for HEV seropositivity. 展开更多
关键词 Hepatitis E virus Seroprevalence Veterinarians Hunters Forestry workers Transplant patients Croatia
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基于人工培养的浮萍快速无性繁殖营养条件研究 认领 引用 被引量：1
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作者 高晓钰 曹特 +2 位作者 倪乐意 张霄林 丑庆川 《水生生物学报》 CAS CSCD 北大核心 2022年第7期1097-1104,共8页
为探究并优化浮萍人工培养技术,研究以广布种紫萍(Spirodela polyrrhiza)和青萍(Lemna minor)为主要研究对象,探索两种浮萍植物在不同营养水平的Hoagland和Hunter培养液中的鲜重、叶状体数的生长变化状况。结果表明:(1)紫萍和青萍鲜重在... 为探究并优化浮萍人工培养技术,研究以广布种紫萍(Spirodela polyrrhiza)和青萍(Lemna minor)为主要研究对象,探索两种浮萍植物在不同营养水平的Hoagland和Hunter培养液中的鲜重、叶状体数的生长变化状况。结果表明:(1)紫萍和青萍鲜重在Hoagland培养液的不同营养水平下先增加后减少,而在Hunter营养液中呈持续增长趋势;两种浮萍的鲜重最大相对增长率(RGR)分别为0.11和0.18,鲜重受浮萍品种和培养基类型及其不同营养水平影响显著(P<0.05),以青萍在Hunter原液培养基下的无性繁殖产生的生物量最高。(2)紫萍和青萍叶状体数在Hoagland培养液的不同营养水平下先增加后减少,而同鲜重一样在Hunter营养液中呈不断增长趋势;两种浮萍的叶状体最大相对增长率分别为0.14和0.19,叶状体生长的RGR变化同样受浮萍品种和培养基类型及营养水平影响显著(P<0.05),以青萍在Hunter原液的营养环境下收获的叶状体数最高。(3)两种浮萍在Hoagland和Hunter营养液的不同营养水平下鲜重/叶状体比呈下降趋势,表明两种浮萍在适应不同营养时优先繁殖子代叶状体,以扩大种的适合度。研究认为Hunter原液可作为广布种青萍的最优培养条件,可实现短时间内收获较大浮萍鲜生物量和叶状体数,为进一步资源化利用提供原材料。 展开更多
关键词 Hoagland Hunter 鲜重 叶状体 相对增长率 繁殖策略 浮萍
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中国广东Hunter综合征患者的T1140C新突变 认领 引用 被引量：6
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作者 郭奕斌 杜传书 《遗传》 CAS 北大核心 2006年第5期521-524,共4页
应用尿黏多糖含量检测、干血滤纸片直接扩增、PCR产物直接测序法对患者及其父母等的IDS基因的突变热点exons 9,3,8进行突变检测。发现患儿IDS基因的exon 8发生一新的错义突变,突变部位在第339位密码子(CTA)内,即cDNA第1 140 bp的T突变... 应用尿黏多糖含量检测、干血滤纸片直接扩增、PCR产物直接测序法对患者及其父母等的IDS基因的突变热点exons 9,3,8进行突变检测。发现患儿IDS基因的exon 8发生一新的错义突变,突变部位在第339位密码子(CTA)内,即cDNA第1 140 bp的T突变为C,导致原339位的“亮氨酸CTA”突变为“脯氨酸CCA”。该患儿为这一突变的半合子,而其母为这一突变的杂合子。该错义突变改变了IDS酶的一级结构和三级空间结构,从而可能引起IDS酶活性大大降低,这可能是该Hunter综合征患者的真正致病原因。 展开更多
关键词 Hunter综合征 黏多糖贮积症Ⅱ型 艾杜糖-2-硫酸酯酶 基因突变 聚合酶链反应 DNA序列分析
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