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Comparison of posterior scleral reinforcement surgery and repeated low-level red-light therapy in controlling high and super high myopia in Chinese children 认领 引用
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作者 Si-Yu Ma Ming-Yuan Yang +2 位作者 Ai-Cun Fu Jia Meng Xiu-Juan Li 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第7期1357-1365,共9页
●AIM:To compare the efficacy of posterior scleral reinforcement(PSR)surgery versus repeated low-level red light therapy(RLRL)treatment in controlling high and super high myopia(HM and SHM)of Chinese children.●METHOD... ●AIM:To compare the efficacy of posterior scleral reinforcement(PSR)surgery versus repeated low-level red light therapy(RLRL)treatment in controlling high and super high myopia(HM and SHM)of Chinese children.●METHODS:This retrospective case analysis enrolled Chinese children with HM(-6.00 to-10.00 D;76 children,120 eyes)or SHM(0.05).In the PSR group,BCVA improved significantly at 1 and 2y in both myopia groups(all P0.05).In the RLRL group,BCVA was significantly improved at 1 and 2y,while AL shortened and SE decreased obviously from 3mo to 2y after treatment(all P<0.05);The SHM group showed greater BCVA improvement and AL reduction than the HM group at 1 and 2y,whereas SE improvement was similar between the two groups.In the control group,BCVA declined significantly,accompanied by continuous increases in AL and SE at the 2-year follow-up(all P<0.05).●CONCLUSION:PSR and RLRL effectively improve BCVA in children with HM and SHM.PSR slows AL and SE progression,whereas RLRL reduces AL and SE,with better BCVA and AL outcomes in SHM at 1 and 2y.Both interventions are safe without severe adverse events within 2y.As a non-surgical approach,RLRL has promising clinical value. 展开更多
关键词 posterior scleral reinforcement surgery repeated low-level red-light therapy high myopia super high myopia axial length spherical equivalent
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Efficient activation of peroxymonosulfate for catalytic degradation of organic pollutants by simultaneously using low-level cobalt ions and calcium carbonate micro-particles 认领 引用 被引量：1
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作者 Yu Zhou Xiaobo Wang +2 位作者 Nan Wang Shuangshuang Huang Lihua Zhu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2025年第5期113-124,共12页
An efficient catalytic system was developed to remove various organic pollutants by simultaneously using low-level cobalt ions,calcium carbonate micro-particles and peroxymonosulfate(PMS).A simple base-induced precipi... An efficient catalytic system was developed to remove various organic pollutants by simultaneously using low-level cobalt ions,calcium carbonate micro-particles and peroxymonosulfate(PMS).A simple base-induced precipitation was used to successfully loaded Co-centered reactive sites onto the surface of CaCO3microparticles.Under optimal conditions at 25°C,10 mg/L methylene blue(MB)could be completely degraded within 10 min with 480μg/L Co2+,0.4 g/L CaCO3microparticles(or 0.4 g/L Co@CaCO3)and 0.1 g/L PMS.The MB degradation followed the pseudo first order kinetics with a rate constant of 0.583 min−1,being 8.3,11.5 and 53.0 times that by using Co-OH(0.07 min−1),Co2+(0.044 min−1)and CaCO3(0.011 min−1)as the catalyst,respectively.It was confirmed that there was a synergistic effect in the catalytic activity between Co species and the CaCO3particles but the major contributor was the highly dispersed Co species.When Co2+-containing simulated electroplating wastewater was used as the Co2+source,not only the added MB was also completely degraded within 5 min in this catalytic system,but also the coexisting heavy metal ions were substantially removed.The presently developed method was applied to simultaneously treat organic wastewater and heavy metals wastewater.The present method was also successfully used to efficiently degrade other organic pollutants including bisphenol A,sulfamethoxazole,rhodamine B,tetrabromobisphenol A,ofloxacin and benzoic acid.A catalytic mechanism was proposed for the PMS activation by Co@CaCO3.The surface of CaCO3particles favors the adsorption of Co2+.More importantly,the surface of CaCO3particles provides plentiful surface-OH and-CO32+,and these surface groups complex with Co2+to producemore catalytically active species such as surface[CoOH]−,resulting in rapid Co2+/Co3+cycling and electron transfer.These interactions cause the observed synergistic effect between Co species and CaCO3particles in PMS activation.Due to good cycle stability,strong anti-interference ability and wide universality,the new method will have broad application prospects. 展开更多
关键词 CaCO3 Low-level cobalt Peroxymonosulfate Oxidative degradation
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Acid gas combustion in the inverse diffusion flame for increasing flame temperature under low-level oxygen enrichment conditions 认领 引用
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作者 Xun Tao Yifan Zhang +7 位作者 Fan Zhou Songling Guo Yunfei Gao Lu Ding Xuezhi Duan Zhenghua Dai Guangsuo Yu Fuchen Wang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2025年第12期75-84,共10页
Normal diffusion flame(NDF)of acid gas with a H2S concentration below 50.0%(vol)generally exhibits a low flame temperature in a low-level oxygen enrichment atmosphere under Claus conditions,resulting in flame insta... Normal diffusion flame(NDF)of acid gas with a H2S concentration below 50.0%(vol)generally exhibits a low flame temperature in a low-level oxygen enrichment atmosphere under Claus conditions,resulting in flame instability.This research proposed that inverse diffusion flame(IDF)was applied to acid gas combustion for enhancing flame temperature.IDF of acid gas was compared with fuel gas cocombustion(FGC),split flow of acid gas(SFAG)and high-level oxygen enrichment combustion(OEC).Additionally,the effect of CO2addition on the IDF of H2S was investigated.The results indicated that a stable flame could be observed in the IDF of acid gas,its peak flame temperature was about 801.0 K,which was higher than that in the OEC,FGC and SFAG with a value of about 591.0,684.0 and 734.0 K,respectively.IDF of acid gas was contributed to the formation of sulfur and H2,and mainly involved the oxidation zone and the chemical decomposition and oxidation zone in sequence.In the IDF,CO2exhibited a better oxidation performance,and the peak flame temperature was decreased by about 21.0 K with an increase in CO2addition from 50.8%to 59.5%(vol),whereas significantly enhanced the oxidation reaction rate of H2S,and the peak volume fraction of SO2was increased from 5.812%to 7.075%.The application of IDF to acid gas combustion achieved the objective for improving flame temperature in low-level oxygen enrichment atmosphere under Claus conditions,providing a new perspective in the sulfur recovery and hydrogen production from acid gas. 展开更多
关键词 Acid gas Carbon dioxide Inverse diffusion flame Low-level oxygen enrichment Oxidation Hydrogen
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Radiosonde Measurements and Polar WRF Simulations of Low-Level Wind Jets in the Amundsen Sea Embayment,West Antarctica 认领 引用
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作者 Sai Prabala Swetha CHITTELLA Andrew ORR Pranab DEB 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2025年第10期2142-2152,共11页
We show that low-level jets(LLJs)occurred in 11 out of 22 radiosonde profiles in late austral summer over the coastal region of the Amundsen Sea Embayment,with ten of the LLJs directed offshore.The LLJs had core speed... We show that low-level jets(LLJs)occurred in 11 out of 22 radiosonde profiles in late austral summer over the coastal region of the Amundsen Sea Embayment,with ten of the LLJs directed offshore.The LLJs had core speeds from 9 to 32 m s-1,jet core heights from 80 to 800 m,and were associated with strong,low-level temperature inversions.Seven of the observed offshore LLJs were reasonably simulated by the polar-optimized Weather Research and Forecasting(Polar WRF)model,with output from the model subsequently used to elucidate their generation mechanisms.This study shows that one of the offshore LLJs simulated by the Polar WRF was caused by katabatic winds,while the remaining six were caused by the enhancement of katabatic winds by synoptic forcing in response to a low-pressure system over the Bellingshausen Sea,i.e.,the offshore wind component associated with this system plays a crucial role in the enhancement of the katabatic LLJ.Examination of the Polar WRF output further shows that the LLJs extended over large areas of the Amundsen Sea Embayment,resulting in substantially enhanced near-surface wind speeds over both the Thwaites and Pine Island ice shelves,as well as the open ocean over the continental shelf.The wind-driven forcing associated with the LLJs could perhaps have important impacts on the redistribution of snow over the ice shelves significantly,as well as to affecting sea-ice and ocean circulation variability,including the transport of relatively warm water over the continental shelf to the ice shelf cavities and extension basal melting. 展开更多
关键词 low-level jets temperature inversion katabatic winds synoptic forcing Amundsen Sea Embayment Pine Island Glacier Thwaites Glacier
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Role of the Nocturnal Low-level Jet in the Formation of the Morning Precipitation Peak over the Dabie Mountains 认领 引用 被引量：23
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作者 Peiling FU Kefeng ZHU +2 位作者 Kun ZHAO Bowen ZHOU Ming XUE 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2019年第1期15-28,共14页
The diurnal variation of precipitation over the Dabie Mountains(DBM) in eastern China during the 2013 mei-yu season is investigated with forecasts of a regional convection-permitting model. Simulated precipitation is ... The diurnal variation of precipitation over the Dabie Mountains(DBM) in eastern China during the 2013 mei-yu season is investigated with forecasts of a regional convection-permitting model. Simulated precipitation is verified against surface rain-gauge observations. The observed morning precipitation peak on the windward(relative to the prevailing synoptic-scale wind) side of the DBM is reproduced with good spatial and temporal accuracy. The interaction between the DBM and a nocturnal boundary layer low-level jet(BLJ) due to the inertial oscillation mechanism is shown to be responsible for this precipitation peak. The BLJ is aligned with the lower-level southwesterly synoptic-scale flow that carries abundant moisture.The BLJ core is established at around 0200 LST upwind of the mountains. It moves towards the DBM and reaches maximum intensity at about 70 km ahead of the mountains. When the BLJ impinges upon the windward side of the DBM in the early morning, mechanical lifting of moist air leads to condensation and subsequent precipitation. 展开更多
关键词 nocturnal boundary layer low-level jet diurnal variation precipitation Dabie Mountains meiyu season
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New therapeutic options for persistent low-level viremia in patients with chronic hepatitis B virus infection:Increase of entecavir dosage 认领 引用 被引量：33
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作者 Guo-Qing Yin Jun Li +2 位作者 Bei Zhong Yong-Fong Yang Mao-Rong Wang 《World Journal of Gastroenterology》 SCIE CAS 2021年第8期666-676,共11页
Chronic hepatitis B virus(HBV)infection(CHB)is a public health concern worldwide.Current therapies utilizing nucleos(t)ide analogs(NA)have not resulted in a complete cure for CHB.Furthermore,patients on long-term NA t... Chronic hepatitis B virus(HBV)infection(CHB)is a public health concern worldwide.Current therapies utilizing nucleos(t)ide analogs(NA)have not resulted in a complete cure for CHB.Furthermore,patients on long-term NA treatment often develop low-level viremia(LLV).Persistent LLV,in addition to causing the progression of liver disease or hepatocellular carcinoma,may shed light on the current plight of NA therapy.Here,we review the literature on LLV,NA treatment,and various doses of entecavir to find a strategy for improving the efficacy of this antiviral agent.For LLV patients,three therapeutic options are available,switching to another antiviral monotherapy,interferon-αswitching therapy,and continuing monotherapy.In real-world clinical practice,entecavir overdose has been used in antiviral therapy for CHB patients with NA refractory and persistent LLV,which encouraged us to conduct further in-depth literature survey on dosage and duration related entecavir studies.The studies of pharmacodynamics and pharmacokinetics show that entecavir has the maximal selected index for safety,and has great potential in inhibiting HBV replication,in all of the NAs.In the particular section of the drug approval package published by the United States Food and Drug Administration,entecavir doses 2.5-20 mg/d do not increase adverse events,and entecavir doses higher than 1.0 mg/d might improve the antiviral efficacy.The literature survey led us to two suggestions:(1)Increasing entecavir dose to 1.0 mg/d for the treatment of NA naïve patients with HBV DNA>2×106 IU/mL is feasible and would provide better prognosis;and(2)Further research is needed to assess the long-term toxic effects of higher entecavir doses(2.5 and 5.0 mg/d),which may prove beneficial in treating patients with prior NA treatment,partial virological response,or LLV state. 展开更多
关键词 Chronic hepatitis B virus infection Low-level viremia Therapeutic options Entecavir Dose Efficacy
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The Impact of Low-Level Cloud over the Eastern Subtropical Pacific on the "Double ITCZ" in LASG FGCM-0 认领 引用 被引量：11
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作者 戴福山 宇如聪 +2 位作者 张学洪 俞永强 李江龙 《Advances in Atmospheric Sciences》 SCIE CAS 2003年第3期461-474,共14页
Like many other coupled models, the Flexible coupled General Circulation Model (FGCM-0) suffers from the spurious “Double ITCZ”. In order to understand the “Double ITCZ” in FGCM-0, this study first examines the lo... Like many other coupled models, the Flexible coupled General Circulation Model (FGCM-0) suffers from the spurious “Double ITCZ”. In order to understand the “Double ITCZ” in FGCM-0, this study first examines the low-level cloud cover and the bulk stability of the low troposphere over the eastern subtropical Pacific simulated by the National Center for Atmospheric Research (NCAR) Community Climate Model version 3 (CCM3), which is the atmosphere component model of FGCM-0. It is found that the bulk stability of the low troposphere simulated by CCM3 is very consistent with the one derived from the National Center for Environmental Prediction (NCEP) reanalysis, but the simulated low-level cloud cover is much less than that derived from the International Satellite Cloud Climatology Project (ISCCP) D2 data. Based on the regression equations between the low-level cloud cover from the ISCCP data and the bulk stability of the low troposphere derived from the NCEP reanalysis, the parameterization scheme of low-level cloud in CCM3 is modified and used in sensitivity experiments to examine the impact of low-level cloud over the eastern subtropical Pacific on the spurious “Double ITCZ” in FGCM-0. Results show that the modified scheme causes the simulated low-level cloud cover to be improved locally over the cold oceans. Increasing the low-level cloud cover off Peru not only significantly alleviates the SST warm biases in the southeastern tropical Pacific, but also causes the equatorial cold tongue to be strengthened and to extend further west. Increasing the low-level cloud fraction off California effectively reduces the SST warm biases in ITCZ north of the equator. In order to examine the feedback between the SST and low-level cloud cover off Peru, one additional sensitivity experiment is performed in which the SST over the cold ocean off Peru is restored. It shows that decreasing the SST results in similar impacts over the wide regions from the southeastern tropical Pacific northwestwards to the western/central equatorial Pacific as increasing the low-level cloud cover does. 展开更多
关键词 coupled model double ITCZ low-level cloud
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Nocturnal Low-levelWinds and Their Impacts on Particulate Matter over the Beijing Area 认领 引用 被引量：5
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作者 Yong CHEN Junling AN +5 位作者 Yele SUN Xiquan WANG Yu QU Jingwei ZHANG Zifa WANG Jing DUAN 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2018年第12期1455-1468,共14页
Three-month wind profiles, 260 m PM_1 concentrations [i.e., particulate matter(PM) with an aerodynamic diameter ≤1μm], and carrier-to-noise ratio data at two Beijing sites 55 km apart(urban and suburban) were collec... Three-month wind profiles, 260 m PM_1 concentrations [i.e., particulate matter(PM) with an aerodynamic diameter ≤1μm], and carrier-to-noise ratio data at two Beijing sites 55 km apart(urban and suburban) were collected to analyze the characteristics of low-level nocturnal wind and PM in autumn and winter. Three mountain-plain wind events with wind shear were selected for analysis. The measurements indicated that the maximum wind speeds of the northerly weak low-level jet(LLJ) below 320 m at the suburban site were weaker than those at the urban site, and the LLJ heights and depths at the suburban site were lower than those at the urban site. The nocturnal 140 m mean vertical velocities and the variations in vertical velocity at the urban site were larger than those at the suburban site. A nocturnal breeze with a weak LLJ of ～3 m s-1 noticeably offset nocturnal PM transport due to southerly flow and convergence within the northern urban area of Beijing. Characteristics of the nocturnal LLJ, such as start-up time, structure, intensity, and duration, were important factors in determining the decrease in the nocturnal horizontal range and site-based low-level variations in PM. 展开更多
关键词 weak low-level jet wind direction shear wind lidar low-level PM1
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Meta-analysis of the effect of low-level occupational benzene exposure on human peripheral blood leukocyte counts in China 认领 引用 被引量：6
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作者 Hao Zhang Hong Li +6 位作者 Zhijian Peng Juan Cao Jiemeng Bao Lei Li Xuezhong Wang Yuanyuan Ji Zhuojiong Chen 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2022年第4期204-210,共7页
To investigate the effect of low-level occupational benzene exposure on human peripheral blood leukocyte counts of the workers,domestic and foreign published research data on the change of human peripheral blood leuko... To investigate the effect of low-level occupational benzene exposure on human peripheral blood leukocyte counts of the workers,domestic and foreign published research data on the change of human peripheral blood leukocyte counts under low-level occupational benzene exposure from January 1990 to December 2020 were collected and analyzed.According to the literature inclusion and exclusion criteria,18 independent studies from 12 publications were selected for meta-analysis to explore the effect of low-level occupational benzene exposure on human peripheral blood leukocyte counts.The results showed that the peripheral blood leukocyte counts abnormal rates of low-level occupational benzene exposure group were higher than those of the control group,and the difference was statistically significant.Low-level occupational benzene exposure could result in a relatively higher abnormal rate of peripheral blood leukocyte counts in the exposed population,indicating that low-level occupational benzene exposure at workplaces specified by the current benzene occupational exposure limit in China would affect the peripheral blood leukocyte counts of the workers,thus benzene with concentrations under the limit in the ambient air of workplace could be still harmful to the health of the exposed workers.The results of this study could provide a scientific basis for future revision of the benzene occupational exposure limit in China,and could also be a reference for the formulation of environmental standard concerning benzene in China in the future. 展开更多
关键词 Benzene at workplaces Low-level occupational exposure Peripheral blood Leukocyte Meta-analysis
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A novel method for gamma spectrum analysis of low-level and intermediate-level radioactive waste 认领 引用 被引量：8
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作者 Hui Yang Xin-Yu Zhang +4 位作者 Wei-Guo Gu Bing Dong Xue-Zhi Jiang Wen-Tao Zhou De-Zhong Wang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第6期199-213,共15页
The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral ... The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral analysis method is proposed in this study.In this method,overlapping peaks are located using a continuous wavelet transform.An improved quadratic convolution method is proposed to calculate the widths of the peaks and establish a fourth-order filter model to estimate the Compton edge baseline with the overlapping peaks.Combined with the adaptive sensitive nonlinear iterative peak,this method can effectively subtracts the background.Finally,a function describing the peak shape as a filter is used to deconvolve the energy spectrum to achieve accurate qualitative and quantitative analyses of the nuclide without the aid of a nuclide library.Gamma spectrum acquisition experiments for standard point sources of Cs-137 and Eu-152,a segmented gamma scanning experiment for a 200 L standard drum,and a Monte Carlo simulation experiment for triple overlapping peaks using the closest energy of three typical LILW nuclides(Sb-125,Sb-124,and Cs-134)are conducted.The results of the experiments indicate that(1)the novel method and gamma vision(GV)with an accurate nuclide library have the same spectral analysis capability,and the peak area calculation error is less than 4%;(2)compared with the GV,the analysis results of the novel method are more stable;(3)the novel method can be applied to the activity measurement of LILW,and the error of the activity reconstruction at the equivalent radius is 2.4%;and(4)The proposed novel method can quantitatively analyze all nuclides in LILW without a nuclide library.This novel method can improve the accuracy and precision of LILW measurements,provide key technical support for the reasonable disposal of LILW,and ensure the safety of humans and the environment. 展开更多
关键词 HPGe detector Low-level and intermediate-level radioactive waste Gamma spectrum analysis method Deconvolution method Continuous wavelet transform
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The Roles of Low-level Jets in “21·7” Henan Extremely Persistent Heavy Rainfall Event 认领 引用 被引量：36
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作者 Yuhan LUO Yu DU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2023年第3期350-373,共24页
An extremely heavy rainfall event lasting from 17 to 22 July 2021 occurred in Henan Province of China, with accumulated precipitation of more than 1000 mm over a 6-day period that exceeded its mean annual precipitatio... An extremely heavy rainfall event lasting from 17 to 22 July 2021 occurred in Henan Province of China, with accumulated precipitation of more than 1000 mm over a 6-day period that exceeded its mean annual precipitation. The present study examines the roles of persistent low-level jets(LLJs) in maintaining the precipitation using surface station observations and reanalysis datasets. The LLJs triggered strong ascending motions and carried moisture mainly from the outflow of Typhoon In-fa(2021). The varying directions of the LLJs well corresponded to the meridional shifts of the rainfall. The precipitation rate reached a maximum during 20-21 July as the LLJs strengthened and expanded vertically into double LLJs, including synoptic-weather-system-related LLJs(SLLJs) at 850–700 hPa and boundary-layer jets(BLJs)at ~950 hPa. The coupling of the SLLJ and BLJ provided strong mid-and low-level convergence on 20 July, whereas the SLLJ produced mid-level divergence at its entrance that coupled with low-level convergence at the terminus of the BLJ on21 July. The formation mechanisms of the two types of LLJs are further examined. The SLLJs and the low-pressure vortex(or inverted trough) varied synchronously as a whole and were affected by the southwestward movement of the WPSH in the rainiest period. The persistent large total pressure gradient force at low levels also maintained the strength of low-level geostrophic winds, thus sustaining the BLJs on the synoptic scale. The results based on a Du-Rotunno 1D model show that the Blackadar and Holton mechanisms jointly governed the BLJ dynamics on the diurnal scale. 展开更多
关键词 extremely persistent heavy rainfall low-level jet dynamic and thermodynamic effect diurnal cycle
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Impacts of an Improved Low-Level Cloud Scheme on the Eastern Pacific ITCZ-Cold Tongue Complex 认领 引用 被引量：4
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作者 戴福山 宇如聪 +2 位作者 张学洪 俞永强 李江龙 《Advances in Atmospheric Sciences》 SCIE CAS 2005年第4期559-574,共16页
A statistically-based low-level cloud parameterization scheme is introduced, modified, and applied in the Flexible coupled General Circulation Model (FGCM-O). It is found that the low-level cloud scheme makes improved... A statistically-based low-level cloud parameterization scheme is introduced, modified, and applied in the Flexible coupled General Circulation Model (FGCM-O). It is found that the low-level cloud scheme makes improved simulations of low-level cloud fractions and net surface shortwave radiation fluxes in the subtropical eastern oceans off western coasts in the model. Accompanying the improvement in the net surface shortwave radiation fluxes, the simulated distribution of SSTs is more reasonably asymmetrical about the equator in the tropical eastern Pacific, which suppresses, to some extent, the development of the double ITCZ in the model. Warm SST biases in the ITCZ north of the equator are more realistically reduced, too. But the equatorial cold tongue is strengthened and extends further westward, which reduces the precipitation rate in the western equatorial Pacific but increases it in the ITCZ north of the equator in the far eastern Pacific. It is demonstrated that the low-level cloud-radiation feedback would enhance the cooperative feedback between the equatorial cold tongue and the ITCZ. Based on surface layer heat budget analyses, it is demonstrated that the reduction of SSTs is attributed to both the thermodynamic cooling process modified by the increase of cloud fractions and the oceanic dynamical cooling processes associated with the strengthened surface wind in the eastern equatorial Pacific, but it is mainly attributed to oceanic dynamical cooling processes associated with the strengthening of surface wind in the central and western equatorial Pacific. 展开更多
关键词 parameterization low-level cloud double ITCZ equatorial cold tongue coupled model
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The Screening of Genes Sensitive to Long-Term, Low-Level Microwave Exposure and Bioinformatic Analysis of Potential Correlations to Learning and Memory 认领 引用 被引量：2
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作者 ZHAO Ya Li LI Ying Xian +6 位作者 MA Hong Bo LI Dong LI Hai Liang JIANG Rui KAN Guang Han YANG Zhen Zhong HUANG Zeng Xin 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2015年第8期558-570,共13页
Objective To gain a better understanding of gene expression changes in the brain following microwave exposure in mice. This study hopes to reveal mechanisms contributing to microwave-induced learning and memory dysfun... Objective To gain a better understanding of gene expression changes in the brain following microwave exposure in mice. This study hopes to reveal mechanisms contributing to microwave-induced learning and memory dysfunction. Methods Mice were exposed to whole body 2100 MHz microwaves with specific absorption rates (SARs) of 0.45 W/kg, 1.8 W/kg, and 3.6 W/kg for 1 hour daily for 8 weeks. Differentially expressing genes in the brains were screened using high-density oligonucleotide arrays, with genes showing more significant differences further confirmed by RT-PCR. Results The gene chip results demonstrated that 41 genes (0.45 W/kg group), 29 genes (1.8 W/kg group), and 219 genes (3.6 W/kg group) were differentially expressed. GO analysis revealed that these differentially expressed genes were primarily involved in metabolic processes, cellular metabolic processes, regulation of biological processes, macromolecular metabolic processes, biosynthetic processes, cellular protein metabolic processes, transport, developmental processes, cellular component organization, etc. KEGG pathway analysis showed that these genes are mainly involved in pathways related to ribosome, Alzheimer's disease, Parkinson's disease, long-term potentiation, Huntington's disease, and Neurotrophin signaling. Construction of a protein interaction network identified several important regulatory genes including synbindin (sbdn), Crystallin (CryaB), PPP1CA, Ywhaq, Psap, Psmb1, Pcbp2, etc., which play important roles in the processes of learning and memory. Conclusion Long-term, low-level microwave exposure may inhibit learning and memory by affecting protein and energy metabolic processes and signaling pathways relating to neurological functions or diseases. 展开更多
关键词 Long-term Low-level Microwave Gene chip Learning and memory
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Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats 认领 引用 被引量：2
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作者 Priscilla Hakime Scalize Luiz Gustavo de Sousa +8 位作者 Lígia Maria Napolitano Goncalves Dimitrius Leonardo Pitol Marcelo Palinkas Antonio Augusto Coppi Mariah Acioli Righeti Vitória Ricardo Karina Fittipaldi Bombonato-Prado Simone Cecílio Hallak Regalo Selma Siessere 《Animal Models and Experimental Medicine》 CAS CSCD 2019年第1期51-57,共7页
Background : Osteoporosis can make bone repair difficult. Low-level laser therapy( LLLT) has been shown to be a promising tool for bone neoformation. This study aimed to analyze the effect of LLLT on calvaria bone def... Background : Osteoporosis can make bone repair difficult. Low-level laser therapy( LLLT) has been shown to be a promising tool for bone neoformation. This study aimed to analyze the effect of LLLT on calvaria bone defects of ovariectomized rats using stereology. Methods : Fifty-four Wistar rats were subjected to bilateral ovariectomy, and bone defects were created in calvaria after 150 days. The animals were divided into nine groups(n = ?6 per group), and 24 hours after the bone defects were created they received three, six or 12 sessions of LLLT at 0, 20 or 30 J/cm 2, using a 780-nm low-intensity GaAlAs laser. One-way ANOVA followed by Tukey ' s post hoc test was used for data processing. A difference of P < 0.05 was considered statistically significant. The parameters evaluated were osteocyte density( Nvost), total osteocyte number( Nto ost), trabecular surface density( Sv_t), and trabecular surface area( Sa_t). Results : Data obtained showed that Nto ost, Sv t, and Sa t in group G2 rats were significantly different from G1(0 J/cm^2)( P < 0.05). Compared to group G4, G5 presented higher values for the parameters Sv t and Sa t, and G6 presented significantly higher values for almost all the analyzed parameters( Nv ost, Ntoost, Sv_t, and Sa t)( P < 0.05). Compared to group G7, G8 showed a higher value only for the parameter Sa t, and G9 showed significantly higher values for parameters Nv ost, Nto ost, Sv_t, and Sa_t. Conclusion : We conclude that LLLT stimulated bone neoformation and contributed to an increase in the total number of osteocytes, especially with a laser energy density of 30 J/cm^2 given for six and 12 sessions. 展开更多
关键词 bone low-level laser therapy osteocytes osteoporosis
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Integration of Low-level Waste Heat Recovery and Liquefied Nature Gas Cold Energy Utilization 认领 引用 被引量：16
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作者 白菲菲 张早校 《Chinese Journal of Chemical Engineering》 SCIE EI CAS 2008年第1期95-99,共5页
Two novel thermal cycles based on Brayton cycle and Rankine cycle are proposed, respectively, which integrate the recovery of low-level waste heat and Liquefied Nature Gas （LNG） cold energy utilization for power gen... Two novel thermal cycles based on Brayton cycle and Rankine cycle are proposed, respectively, which integrate the recovery of low-level waste heat and Liquefied Nature Gas （LNG） cold energy utilization for power generation. Cascade utilization of energy is realized in the two thermal cycles, where low-level waste heat,low-temperature exergy and pressure exergy of LNG are utilized efficiently through the system synthesis. The simulations are carried out using the commercial Aspen Plus 10.2, and the results are analyzed. Compared with the conventional Brayton cycle and Rankine cycle, the two novel cycles bring 60.94% and 60% in exergy efficiency, respectively and 53.08% and 52.31% in thermal efficiency, respectively. 展开更多
关键词 recovery of low-level waste heat LNG cold energy utilization power generation cascade utilization
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Long-Term Exposure to Low-Level Ambient Air Pollution and Mortality among 0.3 Million Chinese Older Adults 认领 引用 被引量：2
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作者 Likun Liu Xueli Yuan +10 位作者 Wenqing Ni Jing Wei Tingting Liu Ruijun Xu Yingxin Li Zihua Zhong Yi Zheng Sihan Liang Rui Wang Jian Xu Yuewei Liu 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第12期1362-1372,共11页
Objective Evidence that long-term exposure to ambient air pollution increases mortality among older adults,particularly those residing in low-level air pollution locations,remains scarce.This study investigated the po... Objective Evidence that long-term exposure to ambient air pollution increases mortality among older adults,particularly those residing in low-level air pollution locations,remains scarce.This study investigated the potential links between long-term low-level air pollution exposure and mortality among Chinese older adults.Methods A population-based study with 317,464 individuals aged≥65 years was conducted in Shenzhen,China during 2018 and 2020.Logistic regression models were used to analyze the associations between long-term exposure to air pollution and all-cause mortality,as the primary outcome,as well as non-accidental,cancer and cardiovascular mortality.Results Significant associations of PM1,PM2.5,PM10,SO2,CO,and O3 exposures with a higher risk of all-cause mortality were found.Adjusted odds ratio(OR)for each 1μg/m3 increment was 1.49[95%confidence interval(CI):1.46,1.53]for PM1,1.30(1.27,1.32)for PM2.5,1.05(1.04,1.06)for PM10,5.84(5.39,6.32)for SO2,1.04(1.04,1.05)for CO,and 1.02(1.00,1.03)for O3,respectively.Long-term PM1,PM2.5,PM10,SO2,and CO exposures also elevated the risks of non-accidental,cancer and cardiovascular mortality.Conclusion Long-term low-level air pollution exposure was associated with an increased mortality risk among Chinese older adults. 展开更多
关键词 Ambient air pollution Mortality Older adults Population-based study Low-level concentrations
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Axial length shortening in myopic children with Stickler syndrome after repeated low-level red-light therapy 认领 引用 被引量：2
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作者 Xiang-Hua Tang Meng-Ting Yu +2 位作者 Yin Hu Ming-Guang He Xiao Yang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第10期1712-1717,共6页
AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Thr... AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Three STL children,aged 3,7,and 11y,received RLRL therapy throughout the follow-up period of 17,3,and 6mo,respectively after exclusion of fundus anomalies.Data on best-corrected visual acuity(BCVA),intraocular pressure,cycloplegic subjective refraction,ocular biometrics,scanning laser ophthalmoscope,optical coherence tomography,genetic testing,systemic disease history,and family history were recorded.RESULTS:At the initiation of the RLRL therapy,the spherical equivalent(SE)of 6 eyes from 3 patients ranged from-3.75 to-20.38 D,axial length(AL)were from 23.88 to 30.68 mm,and BCVA were from 0.4 to 1.0(decimal notation).Myopia progression of all six eyes slowed down after RLRL therapy.AL in five out of the six eyes shortened-0.07 to-0.63 mm.No side effects were observed.CONCLUSION:Three cases of STL whose progression of myopic shift and AL elongation are successfully reduced and even reversed after RLRL therapy. 展开更多
关键词 Stickler syndrome axial length shortening myopia repeated low-level red-light therapy
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Characteristics and Formation Mechanisms of Low-Level Jets in Northeastern China 认领 引用 被引量：1
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作者 Hailong SHU Fan ZHANG +4 位作者 Yu DU Yue WANG Huichuang GUO Zhen SONG Qinghong ZHANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第12期2432-2445,共14页
This study examines low-level jets(LLJs)across Northeastern China during both warm(June-September)and cold seasons(December-March)from 1957 to 2021,using fifth generation of the European Centre for Medium-Range Weathe... This study examines low-level jets(LLJs)across Northeastern China during both warm(June-September)and cold seasons(December-March)from 1957 to 2021,using fifth generation of the European Centre for Medium-Range Weather Forecasts reanalysis data with 25-km resolution.LLJs manifest in two prominent regions,one along the leeward flank of the Da Hinggan Ling Mountains in the cold season and another at the center of Northeastern China in the warm season.The intricate interplay between ambient circulation and terrain shapes LLJ distribution,altitudes,wind directions,diurnal cycles,and seasonal diversities.During the warm season,prevailing southwesterly LLJs are found at 925 hPa,while the cold season features stronger and more frequent northwesterly LLJs at 875 hPa.Analysis of the diurnal patterns reveals distinctive behaviors of LLJs in the cold and warm seasons.During the warm season,the single peak in LLJ occurrence emerges around midnight;conversely,in the cold season,LLJs are most frequent shortly before midnight,with an additional sub-peak in the morning.A momentum budget analysis establishes mechanisms underlying these two distinct diurnal variations.In both seasons,the diurnal variation of LLJs is predominately driven by an inertial oscillation and mountain-valley circulations.However,the sub-peak observed in the cold-season morning arises from the thermodynamic and dynamic interaction between the low-level atmosphere and complex terrain. 展开更多
关键词 low-level jet seasonal disparities diurnal variation inertial oscillation terrain-flow interaction
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Analysis of the Characteristics of the Low-level Jets in the Middle Reaches of the Yangtze River during the Mei-yu Season 认领 引用 被引量：1
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作者 Chunguang CUI Wen ZHOU +5 位作者 Hao YANG Xiaokang WANG Yi DENG Xiaofang WANG Guirong XU Jingyu WANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2023年第4期711-724,共14页
Here,we analyze the characteristics and the formation mechanisms of low-level jets(LLJs)in the middle reaches of the Yangtze River during the 2010 mei-yu season using Wuhan station radiosonde data and the fifth genera... Here,we analyze the characteristics and the formation mechanisms of low-level jets(LLJs)in the middle reaches of the Yangtze River during the 2010 mei-yu season using Wuhan station radiosonde data and the fifth generation of the European Centre for Medium-Range Weather Forecasts(ERA5)reanalysis dataset.Our results show that the vertical structure of LLJs is characterized by a predominance of boundary layer jets(BLJs)concentrated at heights of 900-1200 m.The BLJs occur most frequently at 2300 LST(LST=UTC+8 hours)but are strongest at 0200 LST,with composite wind velocities>14 m s-1.Synoptic-system-related LLJs(SLLJs)occur most frequently at 0800 LST but are strongest at 1100LST,with composite wind velocities>12 m s-1.Both BLJs and SLLJs are characterized by a southwesterly wind direction,although the wind direction of SLLJs is more westerly,and northeasterly SLLJs occur more frequently than northeasterly BLJs.When Wuhan is south of the mei-yu front,the westward extension of the northwest Pacific subtropical high intensifies,and the low-pressure system in the eastern Tibetan Plateau strengthens,favoring the formation of LLJs,which are closely related to precipitation.The wind speeds on rainstorm days are greater than those on LLJ days.Our analysis of four typical heavy precipitation events shows the presence of LLJs at the center of the precipitation and on its southern side before the onset of heavy precipitation.BLJs were shown to develop earlier than SLLJs. 展开更多
关键词 mei-yu front boundary layer jets synoptic low-level jets heavy rainfall middle reaches of the Yangtze River
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STATISTICAL ANALYSIS OF LOW-LEVEL JET STREAMS IN NANJING AREA BASED ON WIND PROFILER DATA 认领 引用 被引量：1
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作者 陈楠 胡明宝 +1 位作者 张柽柽 徐芬 《Journal of Tropical Meteorology》 SCIE 2016年第3期426-432,共7页
In order to understand the activity characteristics of low-level jets in the Nanjing area,statistical analysis and comparative study are carried out on their monthly and diurnal variations,characteristics of their cor... In order to understand the activity characteristics of low-level jets in the Nanjing area,statistical analysis and comparative study are carried out on their monthly and diurnal variations,characteristics of their cores and accompanying weather conditions using wind profile data in 2005-2008 collected by two wind profilers.The results show that low-level jets have significant monthly and diurnal variations.They occur more frequently in spring and summer than in autumn and winter and are more active in early morning and at night,with the maximum wind speed usually occurring at midnight.The central part of the low-level jet occurs mainly at the height of less than 1400 meters,and the enhancement of central speed is beneficial to the appearance of precipitation.Meanwhile,when the low-level jet appears in summer,it helps cause heavy rain.The statistical results of the boundary wind profiler are well consistent with those of the tropospheric wind profiler.Two kinds of wind profilers also have the capability of continuously detecting the development of low-level jets. 展开更多
关键词 tropospheric wind profiler boundary wind profiler horizontal wind profile low-level jet statistics
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