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An HRMCTS-Based Optimization Method for Efficient Multi-Objective Path Planning 认领 引用
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作者 Qianshu Yang Shuangxi Liu +1 位作者 Xianyu Wu Wei Zhao 《Computers, Materials & Continua》 SCIE EI 2026年第7期2147-2170,共24页
Path planning for unmanned systems in complex environments must simultaneously satisfy safety,kinematic feasibility,and real-time performance requirements.Monte Carlo Tree Search(MCTS)offers advantages such as model-f... Path planning for unmanned systems in complex environments must simultaneously satisfy safety,kinematic feasibility,and real-time performance requirements.Monte Carlo Tree Search(MCTS)offers advantages such as model-free operation,strong interpretability,and anytime planning capability,but it suffers from large branching factors,excessive search depths,and poor convergence under sparse reward conditions in high-dimensional state spaces.To address these challenges,this paper proposes a Heuristic Rolling Monte Carlo Tree Search(HRMCTS)framework.First,the path planning problem is formulated as a constrained Markov decision process,where the state consists of position and heading,and actions are discretized heading changes.Second,a heuristic selection strategy incorporating goal-directed guidance and obstacle safety margins is introduced to improve search directionality,while a limited-depth forward simulation with branch pruning is employed during the rollout phase.A multi-objective reward function is designed to integrate distance,goal progress,tangent-based obstacle avoidance,smoothness,and efficiency,thereby jointly optimizing path quality and computational performance.Experiments are conducted in three scenarios:static polygonal environments,dynamic circular obstacle environments,and dynamic polygonal obstacle environments.Simulation results demonstrate that the proposed method offers significant advantages in terms of planning efficiency,environmental adaptability,generalization capability,and interpretability. 展开更多
关键词 Unmanned system path planning MCTS heuristic algorithm reward shaping
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基于MCTS和卷积神经网络的五子棋策略研究 认领 引用 被引量：2
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作者 欧俊臣 沙玲 杨淞文 《软件》 2020年第4期160-164,共5页
随着AlphaGo的诞生,人机对弈和人工智能再次成为研究热点。传统的MCTS(蒙特卡洛树搜索)虽然在迭代搜索方面已有良好的成效,但由于五子棋搜索空间较大,算法极易陷入局部最优化问题,且耗时严重。我们用MCTS和卷积神经网络上设计的策略系统... 随着AlphaGo的诞生,人机对弈和人工智能再次成为研究热点。传统的MCTS(蒙特卡洛树搜索)虽然在迭代搜索方面已有良好的成效,但由于五子棋搜索空间较大,算法极易陷入局部最优化问题,且耗时严重。我们用MCTS和卷积神经网络上设计的策略系统,让其与MCTS进行训练(self-play),使五子棋的策略系统能在一定时间内对自身进行升级,然后又回来继续训练自身,这样得到的五子棋策略系统不仅比传统的MCTS更具有即时性,棋力也更强。 展开更多
关键词 五子棋 卷积神经网络 MCTS
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动态混合局面评估MCTS算法在爱恩斯坦棋中的应用 认领 引用 被引量：3
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作者 宋英健 侯荣旭 +1 位作者 孙嘉荣 史广阔 《沈阳工程学院学报（自然科学版）》 2022年第3期72-76,共5页
爱恩斯坦棋是一种双人不完全信息博弈棋类,目前多用于计算机博弈领域的研究,其较为灵活且有随机性,可使用多种搜索算法对AI进行加强。为了提高AI在搜索时的效率及增强对战时的智能程度,采取了一种基于MCTS搜索并配合动态混合局面评估函... 爱恩斯坦棋是一种双人不完全信息博弈棋类,目前多用于计算机博弈领域的研究,其较为灵活且有随机性,可使用多种搜索算法对AI进行加强。为了提高AI在搜索时的效率及增强对战时的智能程度,采取了一种基于MCTS搜索并配合动态混合局面评估函数的算法,在评估函数中使用了棋子动态估值的方法,并对残局进行了一定的优化。经过多次对弈得出,应用改进算法后的新程序在与其他传统搜索算法程序对战时,显著提高了对弈时的胜率和搜索的效率,有效验证了该算法的实用性。 展开更多
关键词 爱恩斯坦棋 计算机博弈 混合局面评估 MCTS
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A geospatial service composition approach based on MCTS with temporal-difference learning 认领 引用
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作者 Zhuang Can Guo Mingqiang Xie Zhong 《High Technology Letters》 EI CAS 2021年第1期17-25,共9页
With the complexity of the composition process and the rapid growth of candidate services,realizing optimal or near-optimal service composition is an urgent problem.Currently,the static service composition chain is ri... With the complexity of the composition process and the rapid growth of candidate services,realizing optimal or near-optimal service composition is an urgent problem.Currently,the static service composition chain is rigid and cannot be easily adapted to the dynamic Web environment.To address these challenges,the geographic information service composition(GISC) problem as a sequential decision-making task is modeled.In addition,the Markov decision process(MDP),as a universal model for the planning problem of agents,is used to describe the GISC problem.Then,to achieve self-adaptivity and optimization in a dynamic environment,a novel approach that integrates Monte Carlo tree search(MCTS) and a temporal-difference(TD) learning algorithm is proposed.The concrete services of abstract services are determined with optimal policies and adaptive capability at runtime,based on the environment and the status of component services.The simulation experiment is performed to demonstrate the effectiveness and efficiency through learning quality and performance. 展开更多
关键词 geospatial service composition reinforcement learning(RL) Markov decision process(MDP) Monte Carlo tree search(MCTS) temporal-difference(TD)learning
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快速吸收的MCTs 认领 引用
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作者 邢英站 《日用化学工业信息》 2002年第23期4-4,共1页
关键词 MCTs Stepan公司 中链甘油三酯
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面向对象MCTS1.0软件在地下环境污染中应用 认领 引用
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作者 薛强 王惠芸 梁冰 《辽宁工程技术大学学报（自然科学版）》 EI CAS 北大核心 2004年第Z1期233-235,共3页
在综合分析面向对象系统设计的思想、步骤和模型的构建基础之上,采用面向对象技术,基于 VC++和 PowerBuilder 软件平台开发了多相流多组分污染物传输过程的模型计算及仿真分析的可视化软件 MCTS1.0,该软件界面友好,使用方便,且具有灵活... 在综合分析面向对象系统设计的思想、步骤和模型的构建基础之上,采用面向对象技术,基于 VC++和 PowerBuilder 软件平台开发了多相流多组分污染物传输过程的模型计算及仿真分析的可视化软件 MCTS1.0,该软件界面友好,使用方便,且具有灵活性和可扩充性。以石油泄露污染为例,模拟了污染物在地下环境系统中的运移动态和发展趋势,为地下环境系统中石油污染的环境质量评价、污染预测与防治以及地下水资源的开发利用和科学管理提供参考依据。 展开更多
关键词 面向对象技术 MCTS1.0软件 污染物传输 软件的实现
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AquaTree:Deep Reinforcement Learning-Driven Monte Carlo Tree Search for Underwater Image Enhancement 认领 引用 被引量：1
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作者 Chao Li Jianing Wang +1 位作者 Caichang Ding Zhiwei Ye 《Computers, Materials & Continua》 SCIE EI 2026年第3期1444-1464,共21页
Underwater images frequently suffer from chromatic distortion,blurred details,and low contrast,posing significant challenges for enhancement.This paper introduces AquaTree,a novel underwater image enhancement(UIE)meth... Underwater images frequently suffer from chromatic distortion,blurred details,and low contrast,posing significant challenges for enhancement.This paper introduces AquaTree,a novel underwater image enhancement(UIE)method that reformulates the task as a Markov Decision Process(MDP)through the integration of Monte Carlo Tree Search(MCTS)and deep reinforcement learning(DRL).The framework employs an action space of 25 enhancement operators,strategically grouped for basic attribute adjustment,color component balance,correction,and deblurring.Exploration within MCTS is guided by a dual-branch convolutional network,enabling intelligent sequential operator selection.Our core contributions include:(1)a multimodal state representation combining CIELab color histograms with deep perceptual features,(2)a dual-objective reward mechanism optimizing chromatic fidelity and perceptual consistency,and(3)an alternating training strategy co-optimizing enhancement sequences and network parameters.We further propose two inference schemes:an MCTS-based approach prioritizing accuracy at higher computational cost,and an efficient network policy enabling real-time processing with minimal quality loss.Comprehensive evaluations on the UIEB Dataset and Color correction and haze removal comparisons on the U45 Dataset demonstrate AquaTree’s superiority,significantly outperforming nine state-of-the-art methods across five established underwater image quality metrics. 展开更多
关键词 Underwater image enhancement(UIE) Monte Carlo tree search(MCTS) deep reinforcement learning(DRL) Markov decision process(MDP)
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Automatic establishment of discrete fracture network from outcrop:Estimate of fracture length and density via reinforcement learning 认领 引用
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作者 Yupeng Cao Weiren Lin 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第4期2561-2572,共12页
Discrete Fracture Network(DFN)modeling is widely employed to simulate fractured rock masses for various geotechnical applications.However,challenges in statistically characterizing three-dimensional fractures arise du... Discrete Fracture Network(DFN)modeling is widely employed to simulate fractured rock masses for various geotechnical applications.However,challenges in statistically characterizing three-dimensional fractures arise due to orientation,size,truncation,and censoring biases when inferring parameters from two-dimensional rock surface observation.This study introduces a fully automated method that leverages Monte Carlo Tree Search(MCTS),a reinforcement learning-based algorithm,to optimize DFN parameters,including fracture density and length.By defininga reward function that compares the simulated rock masses with observed data,the proposed method iteratively minimizes biases and enhances accuracy.Examined on natural outcrop data of a granitic rock body,this method demonstrates significantimprovements in parameter inference,achieving robust convergence and high fidelityto observed fracture characteristics.The approach offers a practical and efficientsolution for DFN modeling in rock engineering and geological applications. 展开更多
关键词 Fracture length estimation Discrete fracture network(DFN) Monte Carlo Tree Search(MCTS) Reinforcement learning(RL)
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基于DQN调整的AlphaZero残局优化策略在苏拉卡尔塔棋中的应用 认领 引用
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作者 陈鸿翔 邓天奇 +3 位作者 王嘉杰 刘子源 刘明烁 赵国冬 《计算机工程与应用》 EI CSCD 北大核心 2026年第11期162-172,共11页
随着深度学习与强化学习的进步,AlphaZero在围棋、国际象棋及将棋博弈等领域展现出了卓越的性能。然而,庞大的算力需求成为限制AlphaZero在其他棋类游戏应用的主要瓶颈。考虑到不同棋类对AlphaZero模型中超参数的适应性差异,提出一种DQN... 随着深度学习与强化学习的进步,AlphaZero在围棋、国际象棋及将棋博弈等领域展现出了卓越的性能。然而,庞大的算力需求成为限制AlphaZero在其他棋类游戏应用的主要瓶颈。考虑到不同棋类对AlphaZero模型中超参数的适应性差异,提出一种DQN-NCD超参数优化方法。该方法使用深度Q学习动态调控AlphaZero在蒙特卡罗树搜索(MCTS)执行时的模拟节点数量,以优化单次MCTS的模拟质量,加快残局阶段的自博弈数据生成。此外,将MCTS叶子深度及其标准差整合到决策模型输入以及奖励参考中,动态调整平衡参数Cpuct及噪声参数α,优化胜利决策。实验结果表明,DQN-NCD AlphaZero的深度神经网络收敛效果优于原网络,MCTS的单次搜索深度加深了22.47%。DQN-NCD AlphaZero与原始AlphaZero在苏拉卡尔塔棋500局残局状态下,平均先手行棋净胜率为69.88%,平均后手行棋净胜率为57.29%,较原模型胜率有所提高。探讨了AlphaZero在残局游戏中的高效取胜策略的新思路。 展开更多
关键词 AlphaZero 深度Q学习 超参数动态调整 蒙特卡洛树搜索(MCTS)深度 残局优化策略
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Boosting the photodynamic therapy efficiency by modulating lactate-fueled respiration using a hollow MOF nanostructure 认领 引用
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作者 Bei Liu Weizhe Xu +5 位作者 Wenfei Xu Lirong Sun Fanling Zhang Zhaogang Sun Yucheng Cheng Hongqian Chu 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第5期491-496,共6页
Lactate(LA)is now recognized as a critical carbon source for tumor metabolism,making its transport blockade a promising anticancer therapeutic strategy.In this study,we incorporatedα-cyano-4-hydroxycinnamate(CHC)into... Lactate(LA)is now recognized as a critical carbon source for tumor metabolism,making its transport blockade a promising anticancer therapeutic strategy.In this study,we incorporatedα-cyano-4-hydroxycinnamate(CHC)into hollow-structured Cu S@PCN nanoparticles to inhibit LA influx by suppressing the expression of the monocarboxylate transporter 1(MCT1)in tumor cells.This intervention shifted tumor cell metabolism from LA-fueled oxidative phosphorylation towards anaerobic glycolysis,consequently elevating intratumoral oxygen(O2)levels.The photosensitizer-based metal-organic framework(PCN)component was then able to efficiently convert this elevated O2into abundant reactive oxygen species(ROS),thereby enhancing photodynamic therapy(PDT)efficacy.Notably,the hollow mesoporous Cu S nanoparticle core functioned dually as a high-capacity CHC carrier and a photothermal agent that enables CHC release under near-infrared(NIR)irradiation.Further surface conjugation with folic acidpolyethylene glycol(FA-PEG)imparted tumor-targeting specificity via folate receptor recognition and prolonged systemic circulation.Both in vitro and in vivo evaluations demonstrated the excellent biocompatibility and significantly improved PDT performance of the synthesized CHC-Cu S@PCN-FA(CHC-CP-FA)nanoplatform.These findings underscore the considerable potential of CHC-CP-FA for future cancer treatment applications. 展开更多
关键词 Photodynamic therapy Lactate uptake MCT1 inhibitor Metal-organic framework Photothermal therapy
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面向智能制造实训的行为流感知与自适应路径生成研究 认领 引用
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作者 刘挺 《信息与电脑》 2026年第14期245-247,共3页
教学干预滞后是高职智能制造虚拟仿真实训中尚未解决的难题,这直接拖慢了学生技能内化的进程。为打破这一僵局,文章提出应转化能够实时反映学习者认知状态的连续信号,其关键在于挖掘实训过程中孤立且未被充分利用的操作数据。基于此设想... 教学干预滞后是高职智能制造虚拟仿真实训中尚未解决的难题,这直接拖慢了学生技能内化的进程。为打破这一僵局,文章提出应转化能够实时反映学习者认知状态的连续信号,其关键在于挖掘实训过程中孤立且未被充分利用的操作数据。基于此设想,研究构建了一套以“行为流”感知为核心的自适应路径生成框架。该框架能实时捕获学生在调试、编程等环节留下的细粒度操作序列,借此动态描绘其认知与技能发展的微观轨迹。借助领域知识图谱提供的结构化约束,并引入蒙特卡洛树搜索(Monte Carlo Tree Search,MCTS)算法进行前瞻性推演,系统能够自主完成学习路径的动态规划与实时调优,形成一个从数据感知到干预执行的快速响应闭环。实验结果表明,使用该系统的学生在技能考核成绩与过程性能力成长趋势上均显著优于传统实训组的学生。此框架为实施数据驱动的精准教学干预提供了可行的技术路径,并为透视技能习得的“黑箱”提供了新视角。 展开更多
关键词 行为流感知 动态能力建模 MCTS 自适应路径规划 智能制造实训
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Wen Yang Hua Zhuo formula facilitates embryo implantation by modulating endometrial immune metabolic microenvironment via the MCT/HIF-1α/LDHA pathway 认领 引用
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作者 Xin Wen Xiao-Li Zhao +2 位作者 Zhen Dou Rong Dong Tian Xia 《Traditional Medicine Research》 2026年第5期14-26,共13页
Background:Chronic endometritis(CE)is an important pathological factor contributing to female infertility and recurrent pregnancy loss.Although antibiotics are the primary clinical treatment for CE,they do not effecti... Background:Chronic endometritis(CE)is an important pathological factor contributing to female infertility and recurrent pregnancy loss.Although antibiotics are the primary clinical treatment for CE,they do not effectively improve pregnancy outcomes.Wen Yang Hua Zhuo(WYHZ)is a clinically employed classical formula known for its effects in warming yang,tonifying the spleen and kidneys,and resolving dampness.However,its underlying mechanisms remain unclear.This study aimed to elucidate how WYHZ modulates the immunometabolic microenvironment at the maternal-fetal interface in CE by targeting the MCT/HIF-1α/LDHA pathway to promote embryo implantation.Methods:In vivo,the model of CE was established by intrauterine injection of lipopolysaccharide(LPS)(1 mg/mL)into female C57/BL mice,followed by WYHZ treatment for 3 weeks to evaluate its effects on embryo implantation.Mechanistic studies were further conducted using the MCT-1 inhibitor AZD3965 and adeno-associated virus-mediated HIF-1αknockdown.In vitro,an in vitro CE model consisting of M1 macrophages and Ishikawa,as well as an in vitro embryo implantation model mediated by JAR cells,were constructed using Transwell,and the therapeutic mechanisms of WYHZ was validated using AZD3965 and lentiviral sh HIF-1αintervention.Metabolic enzyme activity assays,protein antibody microarrays,immunofluorescence,Western blotting,Seahorse analysis,and ELISA were employed.Results:WYHZ improved the immune-inflammatory microenvironment at the maternal-fetal interface by reducing pro-inflammatory cytokines and increasing anti-inflammatory factors.In parallel,WYHZ reprogrammed endometrial metabolism by enhancing glycolysis and suppressing mitochondrial oxidative phosphorylation,thereby improving endometrial receptivity and embryo implantation.Mechanistically,WYHZ activated the MCT/HIF-1α/LDHA pathway in endometrial epithelial cells,alleviating inflammatory stress and restoring receptivity.Both AZD3965 intervention and HIF-1αknockdown impaired endometrial receptivity and implantation,effects that were reversed by WYHZ.Conclusion:WYHZ modulates the immunometabolic microenvironment of the endometrium in the context of CE by targeting the activation of the MCT/HIF-1α/LDHA pathway,which improves endometrial receptivity and promotes embryo implantation. 展开更多
关键词 chronic endometritis traditional Chinese medicine embryo implantation immunometabolic microenvironment MCT/HIF-1α/LDHA pathway
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SLC16A2基因变异致Allan-Herndon-Dudley综合征1例 认领 引用
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作者 王姣 赵培伟 陈晓红 《标记免疫分析与临床》 CAS 2026年第2期453-456,共4页
目的分析1例Allan‑Herndon‑Dudley综合征(AHDS)患儿的临床表现、基因变异特点,提高临床医生对该疾病的认识。方法回顾性分析武汉儿童医院收治的1例AHDS患儿的临床资料和基因变异特点,并复习相关文献。结果患儿,男,7月龄,因“7月竖头不稳... 目的分析1例Allan‑Herndon‑Dudley综合征(AHDS)患儿的临床表现、基因变异特点,提高临床医生对该疾病的认识。方法回顾性分析武汉儿童医院收治的1例AHDS患儿的临床资料和基因变异特点,并复习相关文献。结果患儿,男,7月龄,因“7月竖头不稳,不能自主翻身”入院,主要表现为严重神经运动发育迟缓,甲状腺素(T4)、游离甲状腺素(FT4)降低,三碘甲状腺原氨酸(T3)、游离三碘甲状腺原氨酸(FT3)升高,促甲状腺激素(TSH)正常范围,完善全外显子组测序提示患儿SLC16A2基因存在c.604G>A半合子变异,综合临床及遗传信息诊断患儿为AHDS。结论AHDS主要表现为严重的神经认知表型以及外周甲状腺毒症,临床症状缺乏特异性,目前尚无有效治疗方案,基因治疗及甲状腺激素类似物尚处于研究阶段。 展开更多
关键词 AHDS 甲状腺激素 MCT8 SLC16A2 全外显子组测序
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多航天器追逃防博弈策略的混合搜索优化方法 认领 引用 被引量：2
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作者 黄镇垒 韩宏伟 《宇航学报》 EI CAS CSCD 北大核心 2025年第8期1565-1578,共14页
随着航天活动的日益频繁和持续多样化,多航天器轨道博弈问题,尤其是考虑多重角色的博弈机动问题有待深入研究。针对多航天器追逃防问题,建立了摄动动力学模型,明确追逃双方在博弈过程中的角色定义,将复杂的博弈问题拆解为轨道拦截和追... 随着航天活动的日益频繁和持续多样化,多航天器轨道博弈问题,尤其是考虑多重角色的博弈机动问题有待深入研究。针对多航天器追逃防问题,建立了摄动动力学模型,明确追逃双方在博弈过程中的角色定义,将复杂的博弈问题拆解为轨道拦截和追逃博弈两个类型的子博弈问题,据此建立回合制的序列博弈模型。针对最优博弈机动策略计算问题,提出一种动作反应搜索-蒙特卡洛树搜索嵌套式搜索的混合优化策略,避免传统算法的回合性不足与维度爆炸问题。在此基础上,提出基于相对位置矢径的机动方向剪枝策略,根据实际场景快速得到有效机动方向,显著提升算法搜索效率。最后进行多航天器追逃防的数值仿真工作,验证了算法有效性与加速策略的计算优势,分析了博弈制胜的关键因素与多星博弈机理。 展开更多
关键词 轨道拦截 追逃博弈 计算博弈 动作反应搜索(ARS) 蒙特卡洛树搜索(MCTS)
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Multi-Consistency Training for Semi-Supervised Medical Image Segmentation 认领 引用 被引量：1
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作者 WU Changxue ZHANG Wenxi +1 位作者 HAN Jiaozhi WANG Hongyu 《Journal of Shanghai Jiaotong university(Science)》 EI 2025年第4期800-814,共15页
Medical image segmentation is a crucial task in clinical applications.However,obtaining labeled data for medical images is often challenging.This has led to the appeal of semi-supervised learning(SSL),a technique adep... Medical image segmentation is a crucial task in clinical applications.However,obtaining labeled data for medical images is often challenging.This has led to the appeal of semi-supervised learning(SSL),a technique adept at leveraging a modest amount of labeled data.Nonetheless,most prevailing SSL segmentation methods for medical images either rely on the single consistency training method or directly fine-tune SSL methods designed for natural images.In this paper,we propose an innovative semi-supervised method called multi-consistency training(MCT)for medical image segmentation.Our approach transcends the constraints of prior methodologies by considering consistency from a dual perspective:output consistency across different up-sampling methods and output consistency of the same data within the same network under various perturbations to the intermediate features.We design distinct semi-supervised loss regression methods for these two types of consistencies.To enhance the application of our MCT model,we also develop a dedicated decoder as the core of our neural network.Thorough experiments were conducted on the polyp dataset and the dental dataset,rigorously compared against other SSL methods.Experimental results demonstrate the superiority of our approach,achieving higher segmentation accuracy.Moreover,comprehensive ablation studies and insightful discussion substantiate the efficacy of our approach in navigating the intricacies of medical image segmentation. 展开更多
关键词 semi-supervised learning(SSL) multi-consistency training(MCT) medical image segmentation intermediate feature perturbation
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基于MCT组合工况的电动车续驶里程测试方法 认领 引用
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作者 郭成胜 杜闯 +2 位作者 姜智杰 雷利刚 孙龙 《小型内燃机与车辆技术》 CAS 2025年第3期50-56,共7页
美国标准SAE J1634-2017《电动汽车能耗和续航里程测试程序》规定续航超过97 km的电动车续驶里程测试采用MCT组合工况,MCT组合工况由4个UDDS试验循环及2个HFEDS试验循环和等速放电工况组成,工况运行结束后计算UDDS及HFEDS循环权重分配系... 美国标准SAE J1634-2017《电动汽车能耗和续航里程测试程序》规定续航超过97 km的电动车续驶里程测试采用MCT组合工况,MCT组合工况由4个UDDS试验循环及2个HFEDS试验循环和等速放电工况组成,工况运行结束后计算UDDS及HFEDS循环权重分配系数,通过加权能耗分别计算车辆UDDS及HFEDS试验循环续航。基于底盘测功机、环境舱及功率分析仪系统对美标基于权重系数的续驶里程计算方法进行研究,并对组合工况电能特征进行分析,从而形成完整的美标电动车续驶里程测试流程。 展开更多
关键词 电动汽车 UDDS HFEDS MCT 权重系数 底盘测功机
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SMOF与MCT/LCT脂肪乳对消化道出血患者肝功能影响对比研究 认领 引用 被引量：1
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作者 罗国标 林忠秋 +2 位作者 刘国萍 李燕珍 叶勇 《现代医药卫生》 2025年第4期836-839,845,共4页
目的观察消化道出血患者分别使用多种油脂肪乳(SMOF)和中长链脂肪乳(MCT/LCT)前后肝功能情况,对比2种脂肪乳剂对消化道出血患者肝功能的影响。方法采用简单随机抽样方法随机抽取广西医科大学第一附属医院2021年1月1日至2022年12月30日... 目的观察消化道出血患者分别使用多种油脂肪乳(SMOF)和中长链脂肪乳(MCT/LCT)前后肝功能情况,对比2种脂肪乳剂对消化道出血患者肝功能的影响。方法采用简单随机抽样方法随机抽取广西医科大学第一附属医院2021年1月1日至2022年12月30日住院期间肠外营养配方分别使用SMOF及MCT/LCT的消化道出血患者各160例,对比SMOF组及MCT/LCT组患者用药第1、5、10天后肝功能生化指标、天冬氨酸转氨酶/丙氨酸转氨酶(AST/ALT)0.05);用药第10天MCT/LCT组较SMOF组患者总胆红素(TBil)、间接胆红素(IBiL)、γ-谷氨酰转肽酶(GGT)升高更显著,且AST/ALT0.05);用药第5、10天MCT/LCT组较SMOF组Child-Pugh分级为B、C级和急性药物性肝损伤发生率及严重程度更高,差异均有统计学意义(P<0.05)。结论SMOF对比MCT/LCT可有效降低消化道出血患者早期轻、中及重度肝损伤和肠外营养相关的胆汁淤积发生率,保护患者肝功能储备,降低急性药物性肝损伤的发生率及严重程度,对消化道出血患者肝损伤进一步恶化及转归具有一定的保护作用。 展开更多
关键词 SMOF MCT/LCT 消化道出血 肝功能评估 药物性肝损伤
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TA15/TaZrNb multi-element alloy prepared via diffusion bonding:Tensile-strength model and performance of a representative volume element embedded with a sphere 认领 引用
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作者 Wei Chen Fenglei Huang +4 位作者 Chuanting Wang Ruijun Fan Pengjie Zhang Lida Che Aiguo Pi 《Defence Technology（防务技术）》 SCIE EI CAS CSCD 2025年第8期36-51,共16页
In this study, to meet the development and application requirements for high-strength and hightoughness energetic structural materials, a representative volume element of a TA15 matrix embedded with a TaZrNb sphere wa... In this study, to meet the development and application requirements for high-strength and hightoughness energetic structural materials, a representative volume element of a TA15 matrix embedded with a TaZrNb sphere was designed and fabricated via diffusion bonding. The mechanisms of the microstructural evolution of the TaZrNb/TA15 interface were investigated via SEM, EBSD, EDS, and XRD.Interface mechanical property tests and in-situ tensile tests were conducted on the sphere-containing structure, and an equivalent tensile-strength model was established for the structure. The results revealed that the TA15 titanium alloy and joint had high density and no pores or cracks. The thickness of the planar joint was approximately 50-60 μm. The average tensile and shear strengths were 767 MPa and 608 MPa, respectively. The thickness of the spherical joint was approximately 60 μm. The Zr and Nb elements in the joint diffused uniformly and formed strong bonds with Ti without forming intermetallic compounds. The interface exhibited submicron grain refinement and a concave-convex interlocking structure. The tensile fracture surface primarily exhibited intergranular fracture combined with some transgranular fracture, which constituted a quasi-brittle fracture mode. The shear fracture surface exhibited brittle fracture with regular arrangements of furrows. Internal fracture occurred along the spherical interface, as revealed by advanced in-situ X-ray microcomputed tomography. The experimental results agreed well with the theoretical predictions, indicating that the high-strength interface contributes to the overall strength and toughness of the sphere-containing structure. 展开更多
关键词 Diffusion bonding Multi-element alloy Joint microstructure In-situ mechanical test X-ray mCT Sphere-containing structure
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MCT探测器相对光谱响应度测量及漂移修正研究 认领 引用
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作者 王琪雯 赵云龙 +5 位作者 安保林 卢小丰 杨成志 王高 董伟 李仰军 《计量学报》 CSCD 北大核心 2025年第2期160-166,共7页
MCT探测器作为光电探测器的关键元件,其响应度的准确测量对于保证系统的探测精度至关重要。然而,探测器响应度会随温度变化、材料老化以及环境条件的波动产生漂移,影响测量结果的可靠性。现有研究多集中于MCT探测器的波长响应特性,但对... MCT探测器作为光电探测器的关键元件,其响应度的准确测量对于保证系统的探测精度至关重要。然而,探测器响应度会随温度变化、材料老化以及环境条件的波动产生漂移,影响测量结果的可靠性。现有研究多集中于MCT探测器的波长响应特性,但对漂移问题的研究较为薄弱。以热释电探测器为标准探测器,搭建了光电探测器相对光谱响应度测量系统,测量了MCT探测器3.5~5μm的相对光谱响应度,并与已有结果进行对比。实验通过重复切换热释电探测器和MCT探测器,测量了热释电探测器信号的重复性。研究了相对光谱响应度测量典型时间段内MCT探测器随时间的漂移特性,提出了以序列交叉测量方法和线性修正系数来修正准线性漂移影响,将MCT探测器的相对光谱响应度测量结果的相对标准偏差由0.74%降低到了0.38%;利用线性修正系数进行修正更适用于快速的MCT探测器相对光谱响应度的测量。 展开更多
关键词 光学计量 相对光谱响应度 MCT探测器 漂移特性 热释电探测器
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深度制冷红外相机微小振动测量方法研究 认领 引用
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作者 魏江沅 曲文庆 +3 位作者 王坚 马浩然 宁宇 张鸿飞 《核电子学与探测技术》 CAS 北大核心 2025年第8期1146-1154,共9页
近年来,红外天文学发展迅速,已成为天文学的重要分支,地面观测是天文观测的主要手段之一,受地球大气吸收影响,近红外波段只有J、H、K窗口适用于观测。碲镉汞光电探测器(mercury cadmium telluride,MCT)作为目前性能优越的红外探测器需要... 近年来,红外天文学发展迅速,已成为天文学的重要分支,地面观测是天文观测的主要手段之一,受地球大气吸收影响,近红外波段只有J、H、K窗口适用于观测。碲镉汞光电探测器(mercury cadmium telluride,MCT)作为目前性能优越的红外探测器需要在80K的温度下工作,需要制冷机对其进行制冷,一般采用脉管制冷机等机械制冷方式,这类制冷机的特点是会带来振动,对图像清晰度产生影响,不利于天文科学分析,因此本文对采用脉管制冷机深度制冷的K波段MCT相机振动测量开展研究,提出了一种基于核密度估计的星点成像法,并结合三轴加速度计对焦平面的微小振动进行精确测量。实验结果表明,该方法能够有效测得微小振动信息,为图像后处理中的去模糊及成像质量优化提供了可靠的数据支持。 展开更多
关键词 MCT探测器 振动测量 核密度估计法 三轴加速度计
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