The transitional zone between the Sub-Himalaya and the Lesser Himalaya is delineated by the Main Boundary Thrust(MBT)to the north and the Himalayan Frontal Thrust(HFT)to the south.The MBT acts as a major topographic b...The transitional zone between the Sub-Himalaya and the Lesser Himalaya is delineated by the Main Boundary Thrust(MBT)to the north and the Himalayan Frontal Thrust(HFT)to the south.The MBT acts as a major topographic barrier that exerts significant control over longitudinal river valleys and sediment dispersal patterns.This region exhibits pronounced fluvial responses shaped by the interplay of tectonic activity and climatic processes.The present study addresses the need for detailed micro-scale morphometric analysis in this zone to better understand ongoing landscape deformation and neotectonic signatures.A multidisciplinary approach integrating geospatial morphometric techniques with field-based evidence has been employed to investigate terrain evolution.Quantitative morphometric assessments were conducted for 16 sub-basins within an active segment of the MBT,bounded by the Jakhan River to the east and the Giri River to the west.Dimensional changes driven by tectonic uplift and accelerated erosion/incision were evaluated using the hypsometric integral(HI),with most values falling below 0.50,indicating that the drainage basins are in an equilibrium stage.Basin shape(Bs)values range from 0.88 to 6.79,supporting the occurrence of accelerated erosional processes.The stream length gradient index(SL)exhibits values between 86 and 816,suggesting rapid uplift and incision.Similarly,computed values of the Chi(χ)coefficient(479-3706)and the steepness index(Ksn;63-214)reflect differential erosion and strong tectonic control on drainage network evolution.The spatial distribution of tectonic deformation was statistically evaluated using a correlation matrix based on the Relative Index of Active Tectonics(RIAT).The results reveal that approximately 50.33%and 16.25%of the study area fall into high and moderate activity zones,respectively,which is corroborated by historical earthquake records and geomorphic evidence.Neotectonic signatures are preserved in the landscape as river terraces,displaced or tilted strata,V-shaped valleys,river offsets,knickpoints,hanging valleys,and channel migration along the strike of the MBT.These findings underscore the significant role of neotectonics in landform evolution and offer valuable insights for geohazard assessment and mitigation strategies in the rapidly developing foothill regions of the Himalaya.展开更多
This study quantifies and interprets the hydro-morphometric characteristics of the Dayi River Basin to evaluate process-based controls on runoff generation,erosion susceptibility,and groundwater recharge in an ungauge...This study quantifies and interprets the hydro-morphometric characteristics of the Dayi River Basin to evaluate process-based controls on runoff generation,erosion susceptibility,and groundwater recharge in an ungauged tropical crystalline river system in Ghana.Using a 30m resolution ASTER Digital Elevation Model(ASTER DEM),hydro-morphometric parameters encompassing linear,areal,and relief characteristics were derived.The results revealed an elongated basin with a dendritic drainage pattern,as indicated by a low elongation ratio(0.46),form factor(0.17),and circularity ratio(0.26).The basin further exhibited low drainage density(0.79 km km−2),coarse drainage texture(0.32),long length of overland flow(0.63 km),and high infiltration potential,collectively reflecting a structurally controlled hydro-geomorphic river system with enhanced groundwater recharge.These characteristics regulate runoff distribution,erosion,and groundwater recharge within a dual-aquifer system,enhancing the basin′s hydrogeomorphic resilience.The basin-scale hydrological storage coefficient(1.6)indicates a high storage potential,resulting in attenuated runoff peaks,reduced flow erosivity,and enhanced groundwater recharge through subsurface percolation.Such a storage-dominated hydrological response indicates that a substantial proportion of rainfall is partitioned into infiltration and subsurface storage,resulting in enhanced groundwater recharge,sustained baseflow contributions,and reduced flash-flood potential in ungauged tropical crystalline river basins.Watersheds such as Tsatsadu,Tafi,Tsibu,and Tsidje exhibit higher infiltration and reduced erosion,indicating suitability for inland valley rice cultivation,whereas Ahava,Aflabo,Hava,and Koloe show elevated runoff,shorter overland flow,and increased flood and erosion risk.Targeted interventions,including check dams,terraces,afforestation,and sustainable cropping systems,are recommended to mitigate hydrological hazards.By linking DEM-derived morphometric indices with dual aquifer characteristics,this study provides a transferable framework for watershed assessment and sustainable water management in datascarce tropical dual aquifer basins,with applicability to Sub-Saharan Africa,South Asia,and other tropical regions.The findings contribute to global efforts toward sustainable water management and climate resilience(SDGs 6 and 13),with implications for agricultural water security(SDG 2)in data-scarce tropical basins.展开更多
Natural resource management is essential to sustain human well-being and the environment.Water and soil are two of the most important natural resources that require careful management.The western part of India faces m...Natural resource management is essential to sustain human well-being and the environment.Water and soil are two of the most important natural resources that require careful management.The western part of India faces multiple challenges,including climatic variability,soil degradation,water scarcity,deforestation,etc.The basin’s sub-watersheds are delineated and prioritised using the Soil and Water Assessment Tool(SWAT)and Sub Watershed Prioritization Tool(SWPT),respectively,using morphometric and topo-hydrological characteristics,and the sub-watersheds are further ranked using Weighted Sum Analysis(WSA).The findings indicate that SWS19,SWS18,SWS1,SWS17,SWS16,and SWS15,which are drained by the rivers Chambal,Kali Sindh,Mashi,Parbati,Parwan,and Beradi,are highly vulnerable sub-watersheds.By integrating remote sensing,GIS techniques,and quantitative morphometric analysis,parameters such as drainage density,stream frequency,bifurcation ratio,and slope gradient were evaluated.The analysis revealed critical sub-watersheds characterized by steep slopes,high drainage density,and poor vegetation cover,indicating their susceptibility to erosion and runoff.The findings underscore the necessity for targeted soil conservation measures,such as contour bunding,afforestation,and water retention structures.This study highlights the utility of geospatial tools for sustainable watershed management and provides a replicable framework for prioritizing sub-watersheds in similar regions.展开更多
Soil erosion in the Hare watershed led to significant land degradation,water pollution,and reduced agricultural productivity.Despite its effects,very few researchers have used combined morphometric and RUSLE model tec...Soil erosion in the Hare watershed led to significant land degradation,water pollution,and reduced agricultural productivity.Despite its effects,very few researchers have used combined morphometric and RUSLE model techniques to quantify soil erosion and thereby prioritize impacted areas.This work used an automated GIS-based tool(SWPT)to prioritize crucial areas based on topohydrological and morphometric factors and predict soil loss in sub-watersheds using the RUSLE model.Land use/cover data were obtained from Landsat imagery,while slope and morphometric information were extracted from digital elevation data with a resolution of 12.5 m.Soil erodibility was determined using Ethiopian soil maps,and rainfall erosivity was computed using meteorological data.An average annual soil loss of 49 t ha-1 yr-1 was observed in the Hare watershed.Sub-watershed 11 was found to be the most affected,with an average annual soil loss of 85.12 t ha-1 yr-1and a compound parameter value(CPV)of 0.059.Subwatershed 17 has the least amount of soil loss,with 3.67t ha-1 yr-1 and a CPV of 1.32.The study emphasizes the usefulness of integrating RUSLE and morphometric analysis for soil and water conservation planning,suggesting a variety of modeling tools in data-sparse locations to quantify and prioritize erosion-prone areas.展开更多
The Uludağ Range of northwest Türkiye forms a key tectonic boundary between the North Anatolian Fault Zone and the Western Anatolia Extensional Region, where active deformation is expressed across a network of st...The Uludağ Range of northwest Türkiye forms a key tectonic boundary between the North Anatolian Fault Zone and the Western Anatolia Extensional Region, where active deformation is expressed across a network of strike-slip and normal faults. To investigate how fault segmentation and kinematics control landscape evolution in this complex orogen, we integrate high-resolution morphometric analysis with paleoseismological data. We extracted key morphometric indices-including Δ-relief, Δ-elevation, Δ-gradient, Δχ, hypsometric integral, channel concavity(m), normalized channel steepness(ksn), and knickpoint distribution-from 10-meter DEMs using open-source geomorphic toolkits. Our results demonstrate pronounced spatial variability in geomorphic signatures and tectonic activity across four divide segments(DS). DS01, associated with the right-lateral Ulubat Fault, exhibits exceptional morphometric stability and minimal disequilibrium, in line with long earthquake recurrence intervals and low Holocene slip rates. In contrast, DS02 and DS03-bounded by the Bursa and Soğukpınar faults-display χ-based divide migration and subtle landscape adjustment. DS04, influenced by the İnegöl and Oylat faults, is characterized by elevated channel steepness, dense knickpoint clustering, and southward divide migration, collectively indicating ongoing uplift and transient drainage adjustment. The strong correspondence between morphometric disequilibrium and documented earthquake recurrence patterns highlights the critical value of integrating geomorphic and paleoseismological datasets. Our findings demonstrate that only through the convergence and cross-validation of multiple independent metrics can the segmented imprint of active deformation be reliably detected-particularly where landscape response is temporally offset from fault activity. The methodological framework developed here provides a robust template for quantifying active structures and their geomorphic consequences and can be widely applied to other tectonically complex mountain belts for seismic hazard assessment and landscape evolution studies.展开更多
An inventory of Rhynchophorus species was carried out to determine their diversity, biogeographical variability and morphometrics. A shotgun trapping method was used at nine sites in three districts over a four-month ...An inventory of Rhynchophorus species was carried out to determine their diversity, biogeographical variability and morphometrics. A shotgun trapping method was used at nine sites in three districts over a four-month period, identifying three species: R. quadrangulus, R. phoenicis, R. ferrugineus and a probable variant of R. phoenicis. Of these species, R. phoenicis stands out as the most widespread palm weevil, while the probable variant of R. phoenicis is considered the rarest subspecies in the Maniema region. The color of the head and elytra is a criterion for distinguishing the different species of Rhynchophorus spp. Morphological criteria indicate that the probable subspecies of R. phoenicis is the largest palm weevil in the Maniema region and even globally. It is followed by R. quadrangulus and, by far, by R. phoenicis. The smallest palm weevil in Maniema is R. ferrugineus. Moreover, these criteria reveal that, for all three species identified, the female is generally larger than the male. This study has the merit of extending the distribution of R. ferrugineus from the Maghreb to the central East of the DRC, and highlighting a subspecies of R. phoenicis. Recognition of the sexes on the basis of the shape of the tip of the abdomen (oval in the male and flat in the female) is an additional contribution.展开更多
To compare the application of traditional morphometric methods(TMMs)and geometric morphometric methods(GMMs)in the study of intraspecific leaf morphological characters of Quercus dentata,fifteen linear measurement ind...To compare the application of traditional morphometric methods(TMMs)and geometric morphometric methods(GMMs)in the study of intraspecific leaf morphological characters of Quercus dentata,fifteen linear measurement indices and thirteen landmarks of leaves were used to study leaf morphology of three provenances(H1,H2,and H3).In TMMs,principal component analysis(PCA)showed that leaf size–related indices played an important role in population classification.Partial least square(PLS)analysis showed that the main morphological characters affecting leaf size were the average depth of the lobes and the length–width ratios.However,the important indices to distinguish the provenances were circularity,leaf width,and length–width ratio.The results of discriminant analysis(DA)showed that 74.0%of H1,68.0%of H2,and 74.0%of H3 were correctly classified.Cluster analysis showed that the Mahalanobis distances between H1 and H2,H1 and H3,and H2 and H3 were 4.3761,11.4629,and 10.2067,respectively.In GMMs,PCA based on symmetrical components showed that the difference in leaf morphology was mainly due to the changing trend of the leaf apex and base,petiole length,and degree of leaf cracking.PLS analysis showed that there was a significant covariation between the leaf symmetrical components and size:as the leaf enlarged,the widest part gradually moved up,and the shape changed from nearly oval to lanceolate.DA results showed that 86.0%and 78.0%of H1 and H2,70.0%and 80.0%of H1 and H3,and 82.0%and 76.0%of H2 and H3 were correctly classified.Canonical variate analysis results showed that the Mahalanobis distances between H1 and H2,H1 and H3,and H2 and H3 were 1.7238,1.5380,and 1.6329,respectively.Both GMMs and TMMs showed significant differences in morphology among the three Q.dentata provenances,but GMMs had higher classification accuracy and could provide more information about leaf shape,whereas TMMs could provide more information about leaf size.Based on our results,GMMs are promising in the study of leaf morphological variation within Q.dentata provenances.展开更多
Commercial farming of anuran species that are declining in the wild raises a need to discriminate wild from farmed frogs.We hypothesized wild frogs might have extended hindlimbs due to greater frequency or intensity o...Commercial farming of anuran species that are declining in the wild raises a need to discriminate wild from farmed frogs.We hypothesized wild frogs might have extended hindlimbs due to greater frequency or intensity of jumping relative to farmed frogs,highlighting a morphometric approach to discrimination of wild from farmed frogs using hindlimb length.In the present study,Dybowski's frog(Rana dybowskii) was used to test this hypothesis.We measured body mass(Mb) and hindlimb length(Lh) of 2-year old farmed frogs and wild frogs aged 2 to 5 years.Dybowski's frog demonstrated significant dimorphism in Mb and Lh.Mb was significantly greater among farmed 2-year old frogs in both sexes(p=0.000),while only among females was Lh significantly greater for wild frogs(p=0.000).Lh/Mb was used as an index for origin discrimination to eliminate the influence of Mb due to variation of husbandry conditions among farms.Mean Lh/Mb for farmed frogs was significantly lower than for wild frogs(p=0.000) in the 2-year old age class.Discrimination correctly classified 84.4% of farmed and 96.3% of wild male frogs.Among females,92.9% of farmed frogs and 90.1% wild frogs were correctly classified.The overall correctness of classification was 92.1% and 90.8% for males and females,respectively.However,Lh/Mb revealed variation with age,resulting in reduced discriminative power for frogs ≥3 years old.We introduced a coefficient Ce to adjust the Lh/Mb of frogs ≥3 years to the level equivalent to 2-year frogs.The adjustment achieved 89.5% for overall correctness of origin for wild males and 92.4% for wild females ≥3 years old.These results show that Lh/Mb is an effective index to discriminate wild from farmed Dybowski's frog.Since the physical demands of jumping are common among anurans,this index is also potentially applicable to other anuran species.展开更多
Selection of high-performance lines with respect to traits of interest is a key step in plant breeding.Genomic prediction allows to determine the genomic estimated breeding values of unseen lines for trait of interest...Selection of high-performance lines with respect to traits of interest is a key step in plant breeding.Genomic prediction allows to determine the genomic estimated breeding values of unseen lines for trait of interest using genetic markers,e.g.single-nucleotide polymorphisms(SNPs),and machine learning approaches,which can therefore shorten breeding cycles,referring to genomic selection(GS).Here,we applied GS approaches in two populations of Solanaceous crops,i.e.tomato and pepper,to predict morphometric and colorimetric traits.The traitswere measured by using scoring-based conventional descriptors(CDs)aswell as by Tomato Analyzer(TA)tool using the longitudinally and latitudinally cut fruit images.The GS performancewas assessed in cross-validations of classificationbased and regression-based machine learning models for CD and TA traits,respectively.The results showed the usage of TA traits and tag SNPs provide a powerful combination to predict morphology and color-related traits of Solanaceous fruits.The highest predictability of 0.89 was achieved for fruit width in pepper,with an average predictability of 0.69 over all traits.The multi-trait GS models are of slightly better predictability than single-trait models for some colorimetric traits in pepper.While model validation performs poorly on wild tomato accessions,the usage as many as one accession per wild species in the training set can increase the transferability of models to unseen populations for some traits(e.g.fruit shape for which predictability in unseen scenario increased from zero to 0.6).Overall,GS approaches can assist the selection of high-performance Solanaceous fruits in crop breeding.展开更多
Sperm head morphology is crucial for male factor infertility diagnosis and assessment of male reproductive potential.Severalcriteria are available to analyze sperm head morphology,but they are limited by poor methodol...Sperm head morphology is crucial for male factor infertility diagnosis and assessment of male reproductive potential.Severalcriteria are available to analyze sperm head morphology,but they are limited by poor methodology comparability and populationapplicability.This study aimed to explore comprehensive and new normal morphometric reference values for spermatozoa heads infertile Asian males.An automated sperm morphology analysis system captured 23152 stained spermatozoa from confirmed fertilemales.Of these samples,1856 sperm head images were annotated by three experienced laboratory technicians as“normal”.Weemployed 14 novel morphometric features to describe sperm head size(head length,head width,length/width ratio,and girth),shape(ellipse intersection over union,girth intersection over union,short-axis symmetry,and long-axis symmetry),area(head,acrosome,postacrosomal areas,and acrosome area ratio),and degrees of acrosome and nuclear uniformity.This straight-forwardmethod for the morphometric analysis of sperm by accurate visual measurements is clinically applicable.The measured parameterspresent valuable information to establish morphometric reference intervals for normal sperm heads in fertile Asian males.Thepresented detailed measurement data will be valuable for interlaboratory comparisons and technician training.In vitro fertilizationand andrology laboratory technicians can use these parameters to perform objective morphology evaluation when assessing malefertilization potential.展开更多
T his study compared and evaluated the efficiency of two otolith shape descriptors(i.e., the elliptic Fourier transform(EFT) and discrete wavelet transform(DWT)) and morphometrics for stock discrimination. To accompli...T his study compared and evaluated the efficiency of two otolith shape descriptors(i.e., the elliptic Fourier transform(EFT) and discrete wavelet transform(DWT)) and morphometrics for stock discrimination. To accomplish this, sample fish from three stocks of yellow croaker L arimichthys polyactis along the Chinese coast(LDB stock from the Liaodong Bay of the Bohai Sea, JZB stock from the Jiaozhou Bay of the Yellow Sea and CJE stock from the Changjiang River estuary of the East China Sea) were used for otolith morphology analyses. The results showed that morphometrics produced an overall classification success rate of 70.8% in contrast with success rates of 80.0% or 82.0% obtained using EFT or DWT, respectively. This suggests that the two shape descriptors comparably discriminated among the stocks and performed more efficiently than morphometrics. During data adjustment and acquisition, some size variables were excluded from the subsequent discriminant analysis for stock discrimination because they were statistically "inef fective," which could reduce the efficiency of morphometrics and lead to relatively low overall classification success. Both EFT and DWT retain the contour coefficients and thus provide a detailed description of otolith shape, which could improve discriminatory efficiency compared with morphometrics.展开更多
Geometric morphometrics (GM) is an important method of shape analysis and increasingly used in a wide range of scientific disciplines. Presently, a single character comparison system of geometric morphometric data i...Geometric morphometrics (GM) is an important method of shape analysis and increasingly used in a wide range of scientific disciplines. Presently, a single character comparison system of geometric morphometric data is used in almost all empirical studies, and this approach is sufficient for many scientific problems. However, the estimation of overall similarity among taxa or objects based on multiple characters is crucial in a variety of contexts (e.g. (semi-)automated identification, phenetic relationships, tracing of character evolution, phylogenetic reconstruction). Here we propose a new web-based tool for merging several geometric morphometrics data files from multiple characters into a single data file. Using this approach information from multiple characters can be compared in combination and an overall similarity estimate can be obtained in a convenient and geometrically rigorous manner. To illustrate our method, we provide an example analysis of 25 dung beetle species with seven Procrustes superimposed landmark data files representing the morphological variation of body features: the epipharynx, right mandible, pronotum, elytra, hindwing, and the metendosternite in dorsal and lateral view. All seven files were merged into a single one containing information on 649 landmark locations. The possible applications of such merged data files in different fields of science are discussed.展开更多
This study presented a quantitative comparison of cockpit and doline karst by examining the numbers and characteristics of typical types of landform entities that are developed in Guilin(Guangxi, China), La Alianza...This study presented a quantitative comparison of cockpit and doline karst by examining the numbers and characteristics of typical types of landform entities that are developed in Guilin(Guangxi, China), La Alianza(PR, USA), Avalton(KY, USA), and Oolitic(IN, USA). Five types of landform entities were defined: isolated hill(IH), clustered hills(CHs), isolated sinkhole(IS), clustered sinkholes(CSs), and clustered hills with sinkholes(CHSs). An algorithm was developed to automatically identify these types of landform entities by examining the contour lines on topographic maps of two cockpit karst areas(Guilin and La Alianza) and two doline karst areas(Oolitic and Avalton). Within each specific study area, the CHSs is the least developed type yet with a larger size and higher relief. The IH and IS entities are smaller in size, lower in relief, and outnumber their clustered counterparts. The total numbers of these types of entities are quite different in cockpit and doline karst areas. Doline karst is characterized by more negative(IS and CSs) than positive(IH and IHs) landforms and vice versa for cockpit karst. For example, the Guilin study area has 1192 positive landform entities in total, which occupy 9.81% of the total study area. It has only 622 negative landform entities occupying only 3.91% of the total study area. By contrast, the doline karst in Oolitic has 130 negative while only 10 positive landform entities. The positive and negative landforms in Oolitic occupy 12.68% and 2.61% of the total study area, respectively. Furthermore, average relief and slope of the landform entities are much higher and steeper in the cockpit karst than the doline karst areas. For instance, the average slope of CHs in Alvaton is 3.90 degrees while it is 19.78 degrees in La Alianza. The average relief of CSs is 4.07 m and 34.29 m in Oolitic and Guilin respectively. Such a difference within a specific area or between the cockpit and doline karst may reveal different controls on the development of karst landscape.展开更多
The morphological characteristics of the hind wing venation of tetrigids were analyzed on the basis of morphometric measurement, with 20 species and 18 different variables selected for this study. Results show that th...The morphological characteristics of the hind wing venation of tetrigids were analyzed on the basis of morphometric measurement, with 20 species and 18 different variables selected for this study. Results show that three principal components have a higher load at the length between the starting point of the costal vein and the tip of the fourth anal vein, between the tip of the costal vein and the tip of the third anal vein, and between the tip of the costal vein and the tip of the eleventh anal vein. There exists a contrast between wing length and width.展开更多
BACKGROUND The development of precision medicine is essential for personalized treatment and improved clinical outcome,whereas biomarkers are critical for the success of precision therapies.AIM To investigate whether ...BACKGROUND The development of precision medicine is essential for personalized treatment and improved clinical outcome,whereas biomarkers are critical for the success of precision therapies.AIM To investigate whether iCEMIGE(integration of CEll-morphometrics,MIcro-biome,and GEne biomarker signatures)improves risk stratification of breast cancer(BC)patients.METHODS We used our recently developed machine learning technique to identify cellular morphometric biomarkers(CMBs)from the whole histological slide images in The Cancer Genome Atlas(TCGA)breast cancer(TCGA-BRCA)cohort.Multivariate Cox regression was used to assess whether cell-morphometrics prognosis score(CMPS)and our previously reported 12-gene expression prognosis score(GEPS)and 15-microbe abundance prognosis score(MAPS)were independent prognostic factors.iCEMIGE was built upon the sparse representation learning technique.The iCEMIGE scoring model performance was measured by the area under the receiver operating characteristic curve compared to CMPS,GEPS,or MAPS alone.Nomogram models were created to predict overall survival(OS)and progress-free survival(PFS)rates at 5-and 10-year in the TCGA-BRCA cohort.RESULTS We identified 39 CMBs that were used to create a CMPS system in BCs.CMPS,GEPS,and MAPS were found to be significantly independently associated with OS.We then established an iCEMIGE scoring system for risk stratification of BC patients.The iGEMIGE score has a significant prognostic value for OS and PFS independent of clinical factors(age,stage,and estrogen and progesterone receptor status)and PAM50-based molecular subtype.Importantly,the iCEMIGE score significantly increased the power to predict OS and PFS compared to CMPS,GEPS,or MAPS alone.CONCLUSION Our study demonstrates a novel and generic artificial intelligence framework for multimodal data integration toward improving prognosis risk stratification of BC patients,which can be extended to other types of cancer.展开更多
Although there were many ancient Chinese mathematicians contributed a lot on geometry, Geometric morphometrics (GM) in modern concept was not firstly proposed by Chinese. The super capability of geometric morphometr...Although there were many ancient Chinese mathematicians contributed a lot on geometry, Geometric morphometrics (GM) in modern concept was not firstly proposed by Chinese. The super capability of geometric morphometries in scientific computing and problem solving has gained a lot of attentions in the world. Until early of 21 centuries, geometric morphometries was introduced into China. Since then, GM was rapidly applied in many research fields. However, it is a pity that GM is still not well-known in China as many works are published out of China. Thus, the special issue "Geometric morphometrics: Current shape and future directions" is organized. The present issue presents a series of contributions in this scientific field. In future, there will be many considerable new developing fields on GM needed to pay more attentions, for instances, 3D geometric morphometrics, 4D analysis, visualization of amber, new machine developing, new software developing, automatic identification system, etc. Once these technical bottle-necks on 3D data collecting and merging geometric morphometric data from multiple characters could be solved, the automatic identification system and other fields based on Big Data would come true.展开更多
The Upper Ordovician Xiazhen Formation in the Jiangshan-Changshan-Yushan (JCY) triangle area on the Zhejiang-Jiangxi provincial border, South China, is composed of a mixed carbonate-siliciclastic sequence representi...The Upper Ordovician Xiazhen Formation in the Jiangshan-Changshan-Yushan (JCY) triangle area on the Zhejiang-Jiangxi provincial border, South China, is composed of a mixed carbonate-siliciclastic sequence representing various shallow-water platform environments. Highly diversified and abundant heliolitid coral faunas are recognized in the formation and occur over time and space in certain stratigraphic horizons and various lithofacies. Heliolites has been studied using multivariate morphometric analysis applied to differentiate species and evaluate intraspecific and interspecific variations. Ten morphological characters quantified by examination and measurement from transverse and longitudinal thin sections and statistically tested allowed selection of effective characters to discriminate species. Results of frequency histograms, correlation analysis and principle component analysis indicated that certain characters would be suitable for cluster analysis, which were performed on principle component score matrices obtained from the raw data set coordinated with coralla by all those characters. Five major clusters at a relative distance of five on the resulting dendrogram of Heliolites are regarded as morphospecies thus making valid taxa: Heliolites tashanensis Lin and Chow, 1977; Heliolites caracolica (Lin and Chow, 1977); Heliolites columella (Lin and Chow, 1977); Heliolites waicunensis Lin and Chow, 1977; and H. sinensis irregularis Lin and Chow, 1977. The discrimination of these morphospecies by the cluster analysis is verified by discriminant analyses and descriptive statistics.展开更多
The DNA content and morphometric features of hepatocellular carcinoma (HCC) and liver cell dysplasia (LCD), including nuclear area, nuclear perimeter, nuclear maximum diameter and nuclear circle diameter, were quantit...The DNA content and morphometric features of hepatocellular carcinoma (HCC) and liver cell dysplasia (LCD), including nuclear area, nuclear perimeter, nuclear maximum diameter and nuclear circle diameter, were quantitatively determined by means of image analysis technology. The results showed that in comparison with normal hepatocytes, LCD had a markedly increased DNA content and nuclear morphometric parameters, but the values were lower than those for HCC. LCD showed a slight increase in nuclear atypia represented by the nuclear irregular index, which was also less than HCC. The findings indicate that LCD may be a precaneerous lesion of HCC, to the cells in an abnormal proliferative state.展开更多
The dynamics of changes in body shape of fast-growing and slow-growing strains of turbot Scophthalmus maximus,and of the differences in body shape between the two strains,were evaluated from 3 to 27 months of age.The ...The dynamics of changes in body shape of fast-growing and slow-growing strains of turbot Scophthalmus maximus,and of the differences in body shape between the two strains,were evaluated from 3 to 27 months of age.The ratios of total length/body length,body width/body length and total length/body width were used as morphometric indices.The two strains exhibited different temporal trends in total length/body length but similar trends in body width/body length and total length/body width.Generally,body width/body length of the two strains increased with time and total length/body width decreased.Thus,the bodies of both fast-growing and slow-growing strains of turbot changed from a narrow to a more rounded shape.However,the ratio total length/body length was generally lower,body width/body length was mostly higher and total length/body width was consistently lower in the fast-growing strain than in the slowgrowing strain.Correlation analysis of the three shape ratios with body weight showed that total length/body length and total length/body width were unsuitable,and that width/body length was suitable,for use as a phenotypic marker for selective breeding of turbot for growth in weight.展开更多
Objective: To study the relationship between the ser- um levels of hyaluronic acid (HA), procollagen type Ⅲ (PCⅢ), collagen type Ⅳ (CIV) and the histologi- cal degree of hepatic fibrosis evaluated by image analysis...Objective: To study the relationship between the ser- um levels of hyaluronic acid (HA), procollagen type Ⅲ (PCⅢ), collagen type Ⅳ (CIV) and the histologi- cal degree of hepatic fibrosis evaluated by image analysis, and the clinical significance of serum HA, PC Ⅲ, C Ⅳ in the diagnosis of hepatic fibrosis in pa- tients with chronic viral hepatitis. Methods: The concentrations of serum HA, PC Ⅲ, C Ⅳ in 151 patients with chronic viral hepatitis were measured by radioimmunoassay. Liver biopsies were performed in all the patients. Histological sections of 4 μm thickness were stained with Masson's trichrome for fibrosis assessment. Morphometric quantitative measurements for hepatic fibrosis assessment in the 4 μm sections were performed using a fully automated image analysis system. Serum levels of HA, PC Ⅲ, and C Ⅳ were analyzed at different stages of liver pa- thology and compared with the morphometric quanti- tative measurements of hepatic fibrosis. Results: The serum levels of HA, PC Ⅲ, C Ⅳ all ele- vated gradually with the progression of the disease, and all reached the highest in patients with liver cir- rhosis. There was a significant difference in the levels of these 3 components between liver cirrhosis group and the other groups (P<0.05). They all increased steadily with the histological stages of hepatic fibrosis, and reached the highest levels in stage Ⅳ. The serum levels of HA, PC Ⅲ, C Ⅳ were all positive- ly correlated with the histological stages of liver sec- tions and the morphometric measurement (P< 0.001). The coefficients with stages were 0.694, 0.493, 0.552 (P<0.001), respectively and with sur- face density of total collagen on liver biopsy sections by image analysis were 0. 715, 0. 595, 0. 573 (P< 0.001), respectively. Conclusion: The serum levels of HA, PC Ⅲ, C Ⅳ were in consistent with the degree of hepatic fibrosis, and the determination of these marks is valuable for detecting hepatic fibrosis.展开更多
基金Department of Petroleum Engineering and Earth Sciences,UPES,for supporting this researchR&D,UPES,for providing a PhD scholarship and contingency to support geological fieldworkDST-ANRF Grant no CRG/2023/000555 for partial financial support for this research.
摘要The transitional zone between the Sub-Himalaya and the Lesser Himalaya is delineated by the Main Boundary Thrust(MBT)to the north and the Himalayan Frontal Thrust(HFT)to the south.The MBT acts as a major topographic barrier that exerts significant control over longitudinal river valleys and sediment dispersal patterns.This region exhibits pronounced fluvial responses shaped by the interplay of tectonic activity and climatic processes.The present study addresses the need for detailed micro-scale morphometric analysis in this zone to better understand ongoing landscape deformation and neotectonic signatures.A multidisciplinary approach integrating geospatial morphometric techniques with field-based evidence has been employed to investigate terrain evolution.Quantitative morphometric assessments were conducted for 16 sub-basins within an active segment of the MBT,bounded by the Jakhan River to the east and the Giri River to the west.Dimensional changes driven by tectonic uplift and accelerated erosion/incision were evaluated using the hypsometric integral(HI),with most values falling below 0.50,indicating that the drainage basins are in an equilibrium stage.Basin shape(Bs)values range from 0.88 to 6.79,supporting the occurrence of accelerated erosional processes.The stream length gradient index(SL)exhibits values between 86 and 816,suggesting rapid uplift and incision.Similarly,computed values of the Chi(χ)coefficient(479-3706)and the steepness index(Ksn;63-214)reflect differential erosion and strong tectonic control on drainage network evolution.The spatial distribution of tectonic deformation was statistically evaluated using a correlation matrix based on the Relative Index of Active Tectonics(RIAT).The results reveal that approximately 50.33%and 16.25%of the study area fall into high and moderate activity zones,respectively,which is corroborated by historical earthquake records and geomorphic evidence.Neotectonic signatures are preserved in the landscape as river terraces,displaced or tilted strata,V-shaped valleys,river offsets,knickpoints,hanging valleys,and channel migration along the strike of the MBT.These findings underscore the significant role of neotectonics in landform evolution and offer valuable insights for geohazard assessment and mitigation strategies in the rapidly developing foothill regions of the Himalaya.
摘要This study quantifies and interprets the hydro-morphometric characteristics of the Dayi River Basin to evaluate process-based controls on runoff generation,erosion susceptibility,and groundwater recharge in an ungauged tropical crystalline river system in Ghana.Using a 30m resolution ASTER Digital Elevation Model(ASTER DEM),hydro-morphometric parameters encompassing linear,areal,and relief characteristics were derived.The results revealed an elongated basin with a dendritic drainage pattern,as indicated by a low elongation ratio(0.46),form factor(0.17),and circularity ratio(0.26).The basin further exhibited low drainage density(0.79 km km−2),coarse drainage texture(0.32),long length of overland flow(0.63 km),and high infiltration potential,collectively reflecting a structurally controlled hydro-geomorphic river system with enhanced groundwater recharge.These characteristics regulate runoff distribution,erosion,and groundwater recharge within a dual-aquifer system,enhancing the basin′s hydrogeomorphic resilience.The basin-scale hydrological storage coefficient(1.6)indicates a high storage potential,resulting in attenuated runoff peaks,reduced flow erosivity,and enhanced groundwater recharge through subsurface percolation.Such a storage-dominated hydrological response indicates that a substantial proportion of rainfall is partitioned into infiltration and subsurface storage,resulting in enhanced groundwater recharge,sustained baseflow contributions,and reduced flash-flood potential in ungauged tropical crystalline river basins.Watersheds such as Tsatsadu,Tafi,Tsibu,and Tsidje exhibit higher infiltration and reduced erosion,indicating suitability for inland valley rice cultivation,whereas Ahava,Aflabo,Hava,and Koloe show elevated runoff,shorter overland flow,and increased flood and erosion risk.Targeted interventions,including check dams,terraces,afforestation,and sustainable cropping systems,are recommended to mitigate hydrological hazards.By linking DEM-derived morphometric indices with dual aquifer characteristics,this study provides a transferable framework for watershed assessment and sustainable water management in datascarce tropical dual aquifer basins,with applicability to Sub-Saharan Africa,South Asia,and other tropical regions.The findings contribute to global efforts toward sustainable water management and climate resilience(SDGs 6 and 13),with implications for agricultural water security(SDG 2)in data-scarce tropical basins.
摘要Natural resource management is essential to sustain human well-being and the environment.Water and soil are two of the most important natural resources that require careful management.The western part of India faces multiple challenges,including climatic variability,soil degradation,water scarcity,deforestation,etc.The basin’s sub-watersheds are delineated and prioritised using the Soil and Water Assessment Tool(SWAT)and Sub Watershed Prioritization Tool(SWPT),respectively,using morphometric and topo-hydrological characteristics,and the sub-watersheds are further ranked using Weighted Sum Analysis(WSA).The findings indicate that SWS19,SWS18,SWS1,SWS17,SWS16,and SWS15,which are drained by the rivers Chambal,Kali Sindh,Mashi,Parbati,Parwan,and Beradi,are highly vulnerable sub-watersheds.By integrating remote sensing,GIS techniques,and quantitative morphometric analysis,parameters such as drainage density,stream frequency,bifurcation ratio,and slope gradient were evaluated.The analysis revealed critical sub-watersheds characterized by steep slopes,high drainage density,and poor vegetation cover,indicating their susceptibility to erosion and runoff.The findings underscore the necessity for targeted soil conservation measures,such as contour bunding,afforestation,and water retention structures.This study highlights the utility of geospatial tools for sustainable watershed management and provides a replicable framework for prioritizing sub-watersheds in similar regions.
摘要Soil erosion in the Hare watershed led to significant land degradation,water pollution,and reduced agricultural productivity.Despite its effects,very few researchers have used combined morphometric and RUSLE model techniques to quantify soil erosion and thereby prioritize impacted areas.This work used an automated GIS-based tool(SWPT)to prioritize crucial areas based on topohydrological and morphometric factors and predict soil loss in sub-watersheds using the RUSLE model.Land use/cover data were obtained from Landsat imagery,while slope and morphometric information were extracted from digital elevation data with a resolution of 12.5 m.Soil erodibility was determined using Ethiopian soil maps,and rainfall erosivity was computed using meteorological data.An average annual soil loss of 49 t ha-1 yr-1 was observed in the Hare watershed.Sub-watershed 11 was found to be the most affected,with an average annual soil loss of 85.12 t ha-1 yr-1and a compound parameter value(CPV)of 0.059.Subwatershed 17 has the least amount of soil loss,with 3.67t ha-1 yr-1 and a CPV of 1.32.The study emphasizes the usefulness of integrating RUSLE and morphometric analysis for soil and water conservation planning,suggesting a variety of modeling tools in data-sparse locations to quantify and prioritize erosion-prone areas.
基金supported by the Disaster and Emergency Management Authority of Türkiye(AFAD)under the project code UDAP-G-18-01。
摘要The Uludağ Range of northwest Türkiye forms a key tectonic boundary between the North Anatolian Fault Zone and the Western Anatolia Extensional Region, where active deformation is expressed across a network of strike-slip and normal faults. To investigate how fault segmentation and kinematics control landscape evolution in this complex orogen, we integrate high-resolution morphometric analysis with paleoseismological data. We extracted key morphometric indices-including Δ-relief, Δ-elevation, Δ-gradient, Δχ, hypsometric integral, channel concavity(m), normalized channel steepness(ksn), and knickpoint distribution-from 10-meter DEMs using open-source geomorphic toolkits. Our results demonstrate pronounced spatial variability in geomorphic signatures and tectonic activity across four divide segments(DS). DS01, associated with the right-lateral Ulubat Fault, exhibits exceptional morphometric stability and minimal disequilibrium, in line with long earthquake recurrence intervals and low Holocene slip rates. In contrast, DS02 and DS03-bounded by the Bursa and Soğukpınar faults-display χ-based divide migration and subtle landscape adjustment. DS04, influenced by the İnegöl and Oylat faults, is characterized by elevated channel steepness, dense knickpoint clustering, and southward divide migration, collectively indicating ongoing uplift and transient drainage adjustment. The strong correspondence between morphometric disequilibrium and documented earthquake recurrence patterns highlights the critical value of integrating geomorphic and paleoseismological datasets. Our findings demonstrate that only through the convergence and cross-validation of multiple independent metrics can the segmented imprint of active deformation be reliably detected-particularly where landscape response is temporally offset from fault activity. The methodological framework developed here provides a robust template for quantifying active structures and their geomorphic consequences and can be widely applied to other tectonically complex mountain belts for seismic hazard assessment and landscape evolution studies.
摘要An inventory of Rhynchophorus species was carried out to determine their diversity, biogeographical variability and morphometrics. A shotgun trapping method was used at nine sites in three districts over a four-month period, identifying three species: R. quadrangulus, R. phoenicis, R. ferrugineus and a probable variant of R. phoenicis. Of these species, R. phoenicis stands out as the most widespread palm weevil, while the probable variant of R. phoenicis is considered the rarest subspecies in the Maniema region. The color of the head and elytra is a criterion for distinguishing the different species of Rhynchophorus spp. Morphological criteria indicate that the probable subspecies of R. phoenicis is the largest palm weevil in the Maniema region and even globally. It is followed by R. quadrangulus and, by far, by R. phoenicis. The smallest palm weevil in Maniema is R. ferrugineus. Moreover, these criteria reveal that, for all three species identified, the female is generally larger than the male. This study has the merit of extending the distribution of R. ferrugineus from the Maghreb to the central East of the DRC, and highlighting a subspecies of R. phoenicis. Recognition of the sexes on the basis of the shape of the tip of the abdomen (oval in the male and flat in the female) is an additional contribution.
基金supported by the National Key R&D Program of China during the 14th Five-year Plan Period(2021YFD2200302)the nonprofit industry research subject of the National Forestry and Grassland Administration in China(Grant Number 201504408)。
摘要To compare the application of traditional morphometric methods(TMMs)and geometric morphometric methods(GMMs)in the study of intraspecific leaf morphological characters of Quercus dentata,fifteen linear measurement indices and thirteen landmarks of leaves were used to study leaf morphology of three provenances(H1,H2,and H3).In TMMs,principal component analysis(PCA)showed that leaf size–related indices played an important role in population classification.Partial least square(PLS)analysis showed that the main morphological characters affecting leaf size were the average depth of the lobes and the length–width ratios.However,the important indices to distinguish the provenances were circularity,leaf width,and length–width ratio.The results of discriminant analysis(DA)showed that 74.0%of H1,68.0%of H2,and 74.0%of H3 were correctly classified.Cluster analysis showed that the Mahalanobis distances between H1 and H2,H1 and H3,and H2 and H3 were 4.3761,11.4629,and 10.2067,respectively.In GMMs,PCA based on symmetrical components showed that the difference in leaf morphology was mainly due to the changing trend of the leaf apex and base,petiole length,and degree of leaf cracking.PLS analysis showed that there was a significant covariation between the leaf symmetrical components and size:as the leaf enlarged,the widest part gradually moved up,and the shape changed from nearly oval to lanceolate.DA results showed that 86.0%and 78.0%of H1 and H2,70.0%and 80.0%of H1 and H3,and 82.0%and 76.0%of H2 and H3 were correctly classified.Canonical variate analysis results showed that the Mahalanobis distances between H1 and H2,H1 and H3,and H2 and H3 were 1.7238,1.5380,and 1.6329,respectively.Both GMMs and TMMs showed significant differences in morphology among the three Q.dentata provenances,but GMMs had higher classification accuracy and could provide more information about leaf shape,whereas TMMs could provide more information about leaf size.Based on our results,GMMs are promising in the study of leaf morphological variation within Q.dentata provenances.
基金supported by the Project of Tackling Key Problems of Science and Technology of Heilongjiang Province, China (GB06B205-3)Program of Wildlife Conservation and Breeding of State Forestry Administration of China (2008)Special Fund for Postgraduate Dissertation of Northeast Forestry University (2009)
摘要Commercial farming of anuran species that are declining in the wild raises a need to discriminate wild from farmed frogs.We hypothesized wild frogs might have extended hindlimbs due to greater frequency or intensity of jumping relative to farmed frogs,highlighting a morphometric approach to discrimination of wild from farmed frogs using hindlimb length.In the present study,Dybowski's frog(Rana dybowskii) was used to test this hypothesis.We measured body mass(Mb) and hindlimb length(Lh) of 2-year old farmed frogs and wild frogs aged 2 to 5 years.Dybowski's frog demonstrated significant dimorphism in Mb and Lh.Mb was significantly greater among farmed 2-year old frogs in both sexes(p=0.000),while only among females was Lh significantly greater for wild frogs(p=0.000).Lh/Mb was used as an index for origin discrimination to eliminate the influence of Mb due to variation of husbandry conditions among farms.Mean Lh/Mb for farmed frogs was significantly lower than for wild frogs(p=0.000) in the 2-year old age class.Discrimination correctly classified 84.4% of farmed and 96.3% of wild male frogs.Among females,92.9% of farmed frogs and 90.1% wild frogs were correctly classified.The overall correctness of classification was 92.1% and 90.8% for males and females,respectively.However,Lh/Mb revealed variation with age,resulting in reduced discriminative power for frogs ≥3 years old.We introduced a coefficient Ce to adjust the Lh/Mb of frogs ≥3 years to the level equivalent to 2-year frogs.The adjustment achieved 89.5% for overall correctness of origin for wild males and 92.4% for wild females ≥3 years old.These results show that Lh/Mb is an effective index to discriminate wild from farmed Dybowski's frog.Since the physical demands of jumping are common among anurans,this index is also potentially applicable to other anuran species.
基金supported by the European Union’s Horizon 2020 research and innovation programme,project PlantaSYST(SGA-CSA No.739582 under FPA No.664620)the BG05M2OP001-1.003-001-C01 projectfinanced by the European Regional Development Fund through the Bulgarian“Science and Education for Smart Growth”Operational Programme.
摘要Selection of high-performance lines with respect to traits of interest is a key step in plant breeding.Genomic prediction allows to determine the genomic estimated breeding values of unseen lines for trait of interest using genetic markers,e.g.single-nucleotide polymorphisms(SNPs),and machine learning approaches,which can therefore shorten breeding cycles,referring to genomic selection(GS).Here,we applied GS approaches in two populations of Solanaceous crops,i.e.tomato and pepper,to predict morphometric and colorimetric traits.The traitswere measured by using scoring-based conventional descriptors(CDs)aswell as by Tomato Analyzer(TA)tool using the longitudinally and latitudinally cut fruit images.The GS performancewas assessed in cross-validations of classificationbased and regression-based machine learning models for CD and TA traits,respectively.The results showed the usage of TA traits and tag SNPs provide a powerful combination to predict morphology and color-related traits of Solanaceous fruits.The highest predictability of 0.89 was achieved for fruit width in pepper,with an average predictability of 0.69 over all traits.The multi-trait GS models are of slightly better predictability than single-trait models for some colorimetric traits in pepper.While model validation performs poorly on wild tomato accessions,the usage as many as one accession per wild species in the training set can increase the transferability of models to unseen populations for some traits(e.g.fruit shape for which predictability in unseen scenario increased from zero to 0.6).Overall,GS approaches can assist the selection of high-performance Solanaceous fruits in crop breeding.
基金supported by the National Natural Science Foundation of China(No.81974226,No.32171264,and No.81974365)the Sichuan Science and Technology Program(No.2021YFS0026 and No.2022YFS0045).
摘要Sperm head morphology is crucial for male factor infertility diagnosis and assessment of male reproductive potential.Severalcriteria are available to analyze sperm head morphology,but they are limited by poor methodology comparability and populationapplicability.This study aimed to explore comprehensive and new normal morphometric reference values for spermatozoa heads infertile Asian males.An automated sperm morphology analysis system captured 23152 stained spermatozoa from confirmed fertilemales.Of these samples,1856 sperm head images were annotated by three experienced laboratory technicians as“normal”.Weemployed 14 novel morphometric features to describe sperm head size(head length,head width,length/width ratio,and girth),shape(ellipse intersection over union,girth intersection over union,short-axis symmetry,and long-axis symmetry),area(head,acrosome,postacrosomal areas,and acrosome area ratio),and degrees of acrosome and nuclear uniformity.This straight-forwardmethod for the morphometric analysis of sperm by accurate visual measurements is clinically applicable.The measured parameterspresent valuable information to establish morphometric reference intervals for normal sperm heads in fertile Asian males.Thepresented detailed measurement data will be valuable for interlaboratory comparisons and technician training.In vitro fertilizationand andrology laboratory technicians can use these parameters to perform objective morphology evaluation when assessing malefertilization potential.
基金Supported by the National Key Basic Research Program of China(973 Program)(No.2015CB453302)the NSFC-Shandong Joint Fund for Marine Science Research Centre(No.U1606404)the Aoshan Science and Technology Innovation Project(No.2015ASKJ02-04)
摘要T his study compared and evaluated the efficiency of two otolith shape descriptors(i.e., the elliptic Fourier transform(EFT) and discrete wavelet transform(DWT)) and morphometrics for stock discrimination. To accomplish this, sample fish from three stocks of yellow croaker L arimichthys polyactis along the Chinese coast(LDB stock from the Liaodong Bay of the Bohai Sea, JZB stock from the Jiaozhou Bay of the Yellow Sea and CJE stock from the Changjiang River estuary of the East China Sea) were used for otolith morphology analyses. The results showed that morphometrics produced an overall classification success rate of 70.8% in contrast with success rates of 80.0% or 82.0% obtained using EFT or DWT, respectively. This suggests that the two shape descriptors comparably discriminated among the stocks and performed more efficiently than morphometrics. During data adjustment and acquisition, some size variables were excluded from the subsequent discriminant analysis for stock discrimination because they were statistically "inef fective," which could reduce the efficiency of morphometrics and lead to relatively low overall classification success. Both EFT and DWT retain the contour coefficients and thus provide a detailed description of otolith shape, which could improve discriminatory efficiency compared with morphometrics.
基金supported by the National Natural Science Foundation of China(31672345,51305057,61379087)the Research Equipment Development Project of Chinese Academy of Sciences(YZ201509)a Humboldt Fellowship(M.B.) from Alexander von Humboldt Foundation
摘要Geometric morphometrics (GM) is an important method of shape analysis and increasingly used in a wide range of scientific disciplines. Presently, a single character comparison system of geometric morphometric data is used in almost all empirical studies, and this approach is sufficient for many scientific problems. However, the estimation of overall similarity among taxa or objects based on multiple characters is crucial in a variety of contexts (e.g. (semi-)automated identification, phenetic relationships, tracing of character evolution, phylogenetic reconstruction). Here we propose a new web-based tool for merging several geometric morphometrics data files from multiple characters into a single data file. Using this approach information from multiple characters can be compared in combination and an overall similarity estimate can be obtained in a convenient and geometrically rigorous manner. To illustrate our method, we provide an example analysis of 25 dung beetle species with seven Procrustes superimposed landmark data files representing the morphological variation of body features: the epipharynx, right mandible, pronotum, elytra, hindwing, and the metendosternite in dorsal and lateral view. All seven files were merged into a single one containing information on 649 landmark locations. The possible applications of such merged data files in different fields of science are discussed.
基金The State Key Laboratory of Resources and Environmental Information System,No.088RA500KA National Natural Science Foundation of China,No.41071250No.41371378
摘要This study presented a quantitative comparison of cockpit and doline karst by examining the numbers and characteristics of typical types of landform entities that are developed in Guilin(Guangxi, China), La Alianza(PR, USA), Avalton(KY, USA), and Oolitic(IN, USA). Five types of landform entities were defined: isolated hill(IH), clustered hills(CHs), isolated sinkhole(IS), clustered sinkholes(CSs), and clustered hills with sinkholes(CHSs). An algorithm was developed to automatically identify these types of landform entities by examining the contour lines on topographic maps of two cockpit karst areas(Guilin and La Alianza) and two doline karst areas(Oolitic and Avalton). Within each specific study area, the CHSs is the least developed type yet with a larger size and higher relief. The IH and IS entities are smaller in size, lower in relief, and outnumber their clustered counterparts. The total numbers of these types of entities are quite different in cockpit and doline karst areas. Doline karst is characterized by more negative(IS and CSs) than positive(IH and IHs) landforms and vice versa for cockpit karst. For example, the Guilin study area has 1192 positive landform entities in total, which occupy 9.81% of the total study area. It has only 622 negative landform entities occupying only 3.91% of the total study area. By contrast, the doline karst in Oolitic has 130 negative while only 10 positive landform entities. The positive and negative landforms in Oolitic occupy 12.68% and 2.61% of the total study area, respectively. Furthermore, average relief and slope of the landform entities are much higher and steeper in the cockpit karst than the doline karst areas. For instance, the average slope of CHs in Alvaton is 3.90 degrees while it is 19.78 degrees in La Alianza. The average relief of CSs is 4.07 m and 34.29 m in Oolitic and Guilin respectively. Such a difference within a specific area or between the cockpit and doline karst may reveal different controls on the development of karst landscape.
基金supported by the National Natural Science Foundation of China(31560604,31160433)the Guangxi Natural Science Foundation(2015GXNSFAA139071)
摘要The morphological characteristics of the hind wing venation of tetrigids were analyzed on the basis of morphometric measurement, with 20 species and 18 different variables selected for this study. Results show that three principal components have a higher load at the length between the starting point of the costal vein and the tip of the fourth anal vein, between the tip of the costal vein and the tip of the third anal vein, and between the tip of the costal vein and the tip of the eleventh anal vein. There exists a contrast between wing length and width.
基金Supported by This work was supported by the Department of Defense(DoD)BCRP,No.BC190820the National Cancer Institute(NCI)at the National Institutes of Health(NIH),No.R01CA184476+1 种基金MCIN/AEI/10.13039/501100011039,No.PID2020-118527RB-I00,and No.PDC2021-121735-I00the“European Union Next Generation EU/PRTR.”the Regional Government of Castile and León,No.CSI144P20.Lawrence Berkeley National Laboratory(LBNL)is a multi-program national laboratory operated by the University of California for the DOE under contract DE AC02-05CH11231.
摘要BACKGROUND The development of precision medicine is essential for personalized treatment and improved clinical outcome,whereas biomarkers are critical for the success of precision therapies.AIM To investigate whether iCEMIGE(integration of CEll-morphometrics,MIcro-biome,and GEne biomarker signatures)improves risk stratification of breast cancer(BC)patients.METHODS We used our recently developed machine learning technique to identify cellular morphometric biomarkers(CMBs)from the whole histological slide images in The Cancer Genome Atlas(TCGA)breast cancer(TCGA-BRCA)cohort.Multivariate Cox regression was used to assess whether cell-morphometrics prognosis score(CMPS)and our previously reported 12-gene expression prognosis score(GEPS)and 15-microbe abundance prognosis score(MAPS)were independent prognostic factors.iCEMIGE was built upon the sparse representation learning technique.The iCEMIGE scoring model performance was measured by the area under the receiver operating characteristic curve compared to CMPS,GEPS,or MAPS alone.Nomogram models were created to predict overall survival(OS)and progress-free survival(PFS)rates at 5-and 10-year in the TCGA-BRCA cohort.RESULTS We identified 39 CMBs that were used to create a CMPS system in BCs.CMPS,GEPS,and MAPS were found to be significantly independently associated with OS.We then established an iCEMIGE scoring system for risk stratification of BC patients.The iGEMIGE score has a significant prognostic value for OS and PFS independent of clinical factors(age,stage,and estrogen and progesterone receptor status)and PAM50-based molecular subtype.Importantly,the iCEMIGE score significantly increased the power to predict OS and PFS compared to CMPS,GEPS,or MAPS alone.CONCLUSION Our study demonstrates a novel and generic artificial intelligence framework for multimodal data integration toward improving prognosis risk stratification of BC patients,which can be extended to other types of cancer.
基金supported by the National Natural Science Foundation of China(31672345)Research Equipment Development Project of Chinese Academy of Sciences(YZ201509)
摘要Although there were many ancient Chinese mathematicians contributed a lot on geometry, Geometric morphometrics (GM) in modern concept was not firstly proposed by Chinese. The super capability of geometric morphometries in scientific computing and problem solving has gained a lot of attentions in the world. Until early of 21 centuries, geometric morphometries was introduced into China. Since then, GM was rapidly applied in many research fields. However, it is a pity that GM is still not well-known in China as many works are published out of China. Thus, the special issue "Geometric morphometrics: Current shape and future directions" is organized. The present issue presents a series of contributions in this scientific field. In future, there will be many considerable new developing fields on GM needed to pay more attentions, for instances, 3D geometric morphometrics, 4D analysis, visualization of amber, new machine developing, new software developing, automatic identification system, etc. Once these technical bottle-necks on 3D data collecting and merging geometric morphometric data from multiple characters could be solved, the automatic identification system and other fields based on Big Data would come true.
基金supported by grants to Prof.Dong-Jin Lee from the Korean Research Foundation
摘要The Upper Ordovician Xiazhen Formation in the Jiangshan-Changshan-Yushan (JCY) triangle area on the Zhejiang-Jiangxi provincial border, South China, is composed of a mixed carbonate-siliciclastic sequence representing various shallow-water platform environments. Highly diversified and abundant heliolitid coral faunas are recognized in the formation and occur over time and space in certain stratigraphic horizons and various lithofacies. Heliolites has been studied using multivariate morphometric analysis applied to differentiate species and evaluate intraspecific and interspecific variations. Ten morphological characters quantified by examination and measurement from transverse and longitudinal thin sections and statistically tested allowed selection of effective characters to discriminate species. Results of frequency histograms, correlation analysis and principle component analysis indicated that certain characters would be suitable for cluster analysis, which were performed on principle component score matrices obtained from the raw data set coordinated with coralla by all those characters. Five major clusters at a relative distance of five on the resulting dendrogram of Heliolites are regarded as morphospecies thus making valid taxa: Heliolites tashanensis Lin and Chow, 1977; Heliolites caracolica (Lin and Chow, 1977); Heliolites columella (Lin and Chow, 1977); Heliolites waicunensis Lin and Chow, 1977; and H. sinensis irregularis Lin and Chow, 1977. The discrimination of these morphospecies by the cluster analysis is verified by discriminant analyses and descriptive statistics.
摘要The DNA content and morphometric features of hepatocellular carcinoma (HCC) and liver cell dysplasia (LCD), including nuclear area, nuclear perimeter, nuclear maximum diameter and nuclear circle diameter, were quantitatively determined by means of image analysis technology. The results showed that in comparison with normal hepatocytes, LCD had a markedly increased DNA content and nuclear morphometric parameters, but the values were lower than those for HCC. LCD showed a slight increase in nuclear atypia represented by the nuclear irregular index, which was also less than HCC. The findings indicate that LCD may be a precaneerous lesion of HCC, to the cells in an abnormal proliferative state.
基金Supported by the Earmarked Fund for Modern Agro-Industry Technology Research System(No.CARS-50-G01)the National High Technology Research and Development Program of China(863 Program)(No.2012AA10A408-8)
摘要The dynamics of changes in body shape of fast-growing and slow-growing strains of turbot Scophthalmus maximus,and of the differences in body shape between the two strains,were evaluated from 3 to 27 months of age.The ratios of total length/body length,body width/body length and total length/body width were used as morphometric indices.The two strains exhibited different temporal trends in total length/body length but similar trends in body width/body length and total length/body width.Generally,body width/body length of the two strains increased with time and total length/body width decreased.Thus,the bodies of both fast-growing and slow-growing strains of turbot changed from a narrow to a more rounded shape.However,the ratio total length/body length was generally lower,body width/body length was mostly higher and total length/body width was consistently lower in the fast-growing strain than in the slowgrowing strain.Correlation analysis of the three shape ratios with body weight showed that total length/body length and total length/body width were unsuitable,and that width/body length was suitable,for use as a phenotypic marker for selective breeding of turbot for growth in weight.
摘要Objective: To study the relationship between the ser- um levels of hyaluronic acid (HA), procollagen type Ⅲ (PCⅢ), collagen type Ⅳ (CIV) and the histologi- cal degree of hepatic fibrosis evaluated by image analysis, and the clinical significance of serum HA, PC Ⅲ, C Ⅳ in the diagnosis of hepatic fibrosis in pa- tients with chronic viral hepatitis. Methods: The concentrations of serum HA, PC Ⅲ, C Ⅳ in 151 patients with chronic viral hepatitis were measured by radioimmunoassay. Liver biopsies were performed in all the patients. Histological sections of 4 μm thickness were stained with Masson's trichrome for fibrosis assessment. Morphometric quantitative measurements for hepatic fibrosis assessment in the 4 μm sections were performed using a fully automated image analysis system. Serum levels of HA, PC Ⅲ, and C Ⅳ were analyzed at different stages of liver pa- thology and compared with the morphometric quanti- tative measurements of hepatic fibrosis. Results: The serum levels of HA, PC Ⅲ, C Ⅳ all ele- vated gradually with the progression of the disease, and all reached the highest in patients with liver cir- rhosis. There was a significant difference in the levels of these 3 components between liver cirrhosis group and the other groups (P<0.05). They all increased steadily with the histological stages of hepatic fibrosis, and reached the highest levels in stage Ⅳ. The serum levels of HA, PC Ⅲ, C Ⅳ were all positive- ly correlated with the histological stages of liver sec- tions and the morphometric measurement (P< 0.001). The coefficients with stages were 0.694, 0.493, 0.552 (P<0.001), respectively and with sur- face density of total collagen on liver biopsy sections by image analysis were 0. 715, 0. 595, 0. 573 (P< 0.001), respectively. Conclusion: The serum levels of HA, PC Ⅲ, C Ⅳ were in consistent with the degree of hepatic fibrosis, and the determination of these marks is valuable for detecting hepatic fibrosis.