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Morus alba leaf extract modulates melanogenesis in enzymatic,cellular,and zebrafish models 认领 引用
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作者 Mirissa Hewage Dumindu Kavinda Su-Yeon Lee +4 位作者 Yung Hyun Choi Seo Min Jeong Chang Soo Lee Hyung Won Ryu Gi-Young Kim 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2026年第6期243-255,I0004-I0021,共13页
Objective:To investigate the modulatory effects of a Morus alba leaf extract(FBCC-EP1619)on melanogenesis using enzymatic,cellular,and zebrafish models.Methods:Phytochemical profiling was conducted using UPLC-QTOF-MS/... Objective:To investigate the modulatory effects of a Morus alba leaf extract(FBCC-EP1619)on melanogenesis using enzymatic,cellular,and zebrafish models.Methods:Phytochemical profiling was conducted using UPLC-QTOF-MS/MS in negative ion mode.Mushroom tyrosinase inhibition was assessed in vitro.Cytotoxicity and melanin content were measured in B16F10 melanoma cells under basal andα-melanocyte-stimulating hormone(α-MSH)-stimulated conditions.An in vivo pigmentation model was established usingα-MSH-treated zebrafish larvae,and pigmentation was quantified.Expression of melanogenesis-related genes(mitfa and tyr)was analyzed by RT-qPCR.Results:FBCC-EP1619 contained diverse phenolic and lipid-derived metabolites.The extract significantly inhibited mushroom tyrosinase activity in a concentration-dependent manner.In B16F10 cells,it did not induce cytotoxicity but increased melanin production.In contrast,inα-MSH-stimulated zebrafish larvae,FBCC-EP1619 attenuated hyperpigmentation and significantly downregulated mitfa and tyr expression,indicating system-and stimulus-dependent regulation.Conclusions:FBCC-EP1619 differentially modulates melanogenesis depending on the biological system,enhancing basal melanin production in vitro while suppressingα-MSH-induced pigmentation in vivo.These findings provide pharmacological support for the ethnopharmacological relevance of Morus alba leaves and warrant further investigation into the underlying molecular mechanisms. 展开更多
关键词 Morus alba Melanogenesis Tyrosinase Hyperpigmentation α-MSH Zebrafish model
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Exploring the therapeutic potential of Morus alba Linne extract in targeting localized adiposity 认领 引用
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作者 CHOI You Yeon JIN Seong chul +4 位作者 KIM Mi Hye BAEK Hee Kyung KIM Dong Hyun OH Sung Hyuk YANG Woong Mo 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2025年第5期970-978,共9页
OBJECTIVE:To determine direct targeting of localized adiposity through Morus alba Linne bark injection based on pharmacology network analysis.METHODS:Male C57BL/6J mice were fed a high-fat diet(HFD)to induce obesity.A... OBJECTIVE:To determine direct targeting of localized adiposity through Morus alba Linne bark injection based on pharmacology network analysis.METHODS:Male C57BL/6J mice were fed a high-fat diet(HFD)to induce obesity.After 6 weeks on HFD,the water extract of Morus alba L.bark(MAB,2 mg/mL)was locally injected into one inguinal fat pad,while saline was injected into the other side,3 times/week for 6 weeks(n=6/group).The water extract of MAB was freeze-dried and then diluted in saline before use.RESULTS:HFD-fed mice treated with local MAB topical injection showed reduced adipocyte weight and size in inguinal fat pads by dual-energy X-ray absorptiometry.No toxicity changes seen in liver,spleen,kidney tissue,or alanine aminotransferase/aspartate aminotransferase levels in serum by MAB injection.Protein levels of phosphorylated insulin receptor substrate-1 and glucose transporter type 4,and mRNA expression of adiponectin,were increased in inguinal adipose tissue injected with MAB locally.Locally MAB injection led to a decrease in glucose-6-phosphatase and phosphoenolpyruvate carboxykinase,linked to gluconeogenesis,while forkhead box protein O1,which regulates these factors,was increased.Moreover,there was an increase in adenosine 5‘-monophosphate-activated protein kinase,related to lipogenesis,as well as elevated levels of hormone-sensitive lipase and fatty acid synthase,both associated with lipolysis.These results support the'insulin signaling pathway'and'regulation of lipolysis in adipocytes'identified in the Kyoto Encyclopedia of Genes and Genomes pathway through network analysis.CONCLUSION:This study suggests that MAB topical injection exhibits localized fat reduction by inhibiting insulin resistance,gluconeogenesis and lipogenesis mediator,while activating lipolysis enzymes within targeted adipose site. 展开更多
关键词 Morus Alba Linne Bark localized fat adiposity obesity network pharmacology
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Functional characterization of key enzymes involved in the biosynthesis of distinctive flavonoids and stilbenoids in Morus notabilis 认领 引用 被引量:1
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作者 Meng-Wen Hu Jie Fu +10 位作者 Ying Lu Xin-Yan Liu Jiao-Zhen Zhang Jiang-Nan Li Dan-Dan Xu Ya-Tong Li Pei-Xi Hao Ming-Xin Cui Lin-Lin Zhi Hong-Xiang Lou Ai-Xia Cheng 《Horticulture Research》 SCIE CSCD 2025年第10期40-54,共15页
The mulberry(Morus notabilis)is a medicinal and edible plant and contains diverse flavonoids and stilbenoids with significant medicinal benefits.The biosynthesis of these compounds has only been partially elucidated.I... The mulberry(Morus notabilis)is a medicinal and edible plant and contains diverse flavonoids and stilbenoids with significant medicinal benefits.The biosynthesis of these compounds has only been partially elucidated.In the present investigation,we identified and characterized two 4-coumarate:coenzyme A ligases(Mn4CL1 and Mn4CL2),two polyketide synthases(MnCHS and MnSTS),three chalcone reductases(MnCHR1-3),and two 2-oxoglutarate-dependent dioxygenases(MnFLS and MnF3H)involved in flavonoids and stilbenoid biosynthesis.MnCHS converts p-coumaroyl-CoA into naringenin and facilitates the novel conversion of 2,4-dihydroxycinnamoyl-CoA to steppogenin,which features hydroxyl groups at the 4'and 6'positions on the B ring.MnSTS could convert p-coumaroyl-CoA and 2,4-dihydroxycinnamoyl-CoA into resveratrol and oxyresveratrol,respectively.Furthermore,MnCHR1 was first identified in mulberry and collaborated with MnCHS to produce isoliquiritigenin and 2,4,2',4'-tetrahydroxychalcone.A co-expression system of Mn4CL1,MnCHS,and MnCHR1 enabled the fermentation production of steppogenin and 2,4,2',4'-tetrahydroxychalcone in engineered Escherichia coli.The in vitro enzymatic assays confirmed that MnFLS showed both FLS and F3H activities,whereas transgenic experiments revealed its predominant FLS function in viuo;MnF3H was confirmed as a bona fide F3H.These findings provide new insights into the flavonoids and stilbenoids biosynthesis pathway in mulberry and suggest a potential parallel pathway for 4',6'-dihydroxylated flavonoids biosynthesis. 展开更多
关键词 polyketide synthases stilbenoids chalcone reductases mnchr chalcone reductases oxoglutarate dependent dioxygenases polyketide synthases mnchs flavonoids Morus notabilis
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Chromosome restructuring and number change during the evolution of Morus notabilis and Morus alba 认领 引用 被引量:9
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作者 Yahui Xuan Bi Ma +3 位作者 Dong Li Yu Tian Qiwei Zeng Ningjia He 《Horticulture Research》 SCIE CSCD 2022年第1期589-602,共14页
Mulberry(Morus spp.)is an economically important plant as the main food plant used for rearing domesticated silkworm and it has multiple uses in traditional Chinese medicine.Two basic chromosome numbers(Morus notabili... Mulberry(Morus spp.)is an economically important plant as the main food plant used for rearing domesticated silkworm and it has multiple uses in traditional Chinese medicine.Two basic chromosome numbers(Morus notabilis,n=7,and Morus alba,n=14)have been reported in the genus Morus,but the evolutionary history and relationship between them remain unclear.In the present study,a 335-Mb high-quality chromosome-scale genome was assembled for the wild mulberry species M.notabilis.Comparative genomic analyses indicated high chromosomal synteny between the 14 chromosomes of cultivated M.alba and the six chromosomes of wild M.notabilis.These results were successfully verified by fluorescence in situ hybridization.Chromosomal fission/fusion events played crucial roles in the chromosome restructuring process between M.notabilis and M.alba.The activity of the centromere was another key factor that ensured the stable inheritance of chromosomes.Our results also revealed that long terminal repeat retrotransposons were a major driver of the genome divergence and evolution of the mulberry genomes after they diverged from each other.This study provides important insights and a solid foundation for studying the evolution of mulberry,allowing the accelerated genetic improvement of cultivated mulberry species. 展开更多
关键词 chromosome restructuring food plant comparative genomics chromosome number change Morus alba genomic analyses rearing domesticated silkworm Morus notabilis
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Phytochemistry,pharmacology,and clinical trials of Morus alba 认领 引用 被引量:67
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作者 Eric Wei-Chiang CHAN Phui-Yan LYE Siu-Kuin WONG 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2016年第1期17-30,共14页
The present review is aimed at providing a comprehensive summary on the botany,utility,phytochemistry,pharmacology,and clinical trials of Morus alba(mulberry or sang shu).The mulberry foliage has remained the primary ... The present review is aimed at providing a comprehensive summary on the botany,utility,phytochemistry,pharmacology,and clinical trials of Morus alba(mulberry or sang shu).The mulberry foliage has remained the primary food for silkworms for centuries.Its leaves have also been used as animal feed for livestock and its fruits have been made into a variety of food products.With flavonoids as major constituents,mulberry leaves possess various biological activities,including antioxidant,antimicrobial,skin-whitening,cytotoxic,anti-diabetic,glucosidase inhibition,anti-hyperlipidemic,anti-atherosclerotic,anti-obesity,cardioprotective,and cognitive enhancement activities.Rich in anthocyanins and alkaloids,mulberry fruits have pharmacological properties,such as antioxidant,anti-diabetic,anti-atherosclerotic,anti-obesity,and hepatoprotective activities.The root bark of mulberry,containing flavonoids,alkaloids and stilbenoids,has antimicrobial,skin-whitening,cytotoxic,anti-inflammatory,and anti-hyperlipidemic properties.Other pharmacological properties of M.alba include anti-platelet,anxiolytic,anti-asthmatic,anthelmintic,antidepressant,cardioprotective,and immunomodulatory activities.Clinical trials on the efficiency of M.alba extracts in reducing blood glucose and cholesterol levels and enhancing cognitive ability have been conducted.The phytochemistry and pharmacology of the different parts of the mulberry tree confer its traditional and current uses as fodder,food,cosmetics,and medicine.Overall,M.alba is a multi-functional plant with promising medicinal properties. 展开更多
关键词 Mulberry Multi-purpose Medicinal properties Morus alba
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Two new prenylflavonoids from Morus nigra L. 认领 引用 被引量:10
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作者 Lei Wang Ting Gong Ruo Yun Chen 《Chinese Chemical Letters》 SCIE CAS 2009年第12期1469-1471,共3页
Two new prenylflavonoids,momigrol E(1)and mornigrol F(2)were isolated from Morus nigra L.Their structures were elucidated on the basis of spectroscopic methods,especially 2D-NMR techniques.
关键词 Morus nigra Moraceae Mornigrols E and F Prenylflavonoid
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基于混合整数线性规划的MORUS初始化阶段的差分分析 认领 引用 被引量:5
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作者 刘帅 关杰 +1 位作者 胡斌 马宿东 《电子与信息学报》 EI CAS CSCD 北大核心 2023年第7期2537-2545,共9页
认证加密算法MORUS是凯撒(CAESAR)竞赛的优胜算法,抗差分分析性能是衡量认证加密算法安全性的重要指标之一。该文研究了MORUS算法初始化阶段的差分性质,首先给出了一个差分推导规则,可以快速获得一条概率较大的差分链。在此基础上利用... 认证加密算法MORUS是凯撒(CAESAR)竞赛的优胜算法,抗差分分析性能是衡量认证加密算法安全性的重要指标之一。该文研究了MORUS算法初始化阶段的差分性质,首先给出了一个差分推导规则,可以快速获得一条概率较大的差分链。在此基础上利用混合整数线性规划(MILP)自动搜索技术求解更优的差分链。为了提高搜索速度,结合MORUS初始化阶段的结构特点给出了分而治之策略。根据ΔIV的重量、取值将MILP模型划分为多个子模型并证明了部分子模型的等价性,大大缩减了模型的求解时间,得到了MORUS初始化阶段1~6步状态更新的最优差分链。最后给出了简化版MORUS的差分-区分攻击,该文的结果较之前的工作有较大的提升。 展开更多
关键词 认证加密算法 MORUS 混合整数线性规划自动搜索 差分分析
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MORUS算法初始化过程的混乱与扩散性质研究 认领 引用 被引量:9
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作者 张沛 关杰 +1 位作者 李俊志 施泰荣 《密码学报》 CSCD 2015年第6期536-548,共13页
MORUS算法是已进入CAESAR竞赛第二轮评选的一个基于流密码的认证加密算法,研究算法的混乱与扩散性质对于评估其安全性来说十分必要.本文首次从完全性和差分扩散性两个角度对MORUS算法初始化过程的混乱与扩散性质进行了研究.我们首先研究... MORUS算法是已进入CAESAR竞赛第二轮评选的一个基于流密码的认证加密算法,研究算法的混乱与扩散性质对于评估其安全性来说十分必要.本文首次从完全性和差分扩散性两个角度对MORUS算法初始化过程的混乱与扩散性质进行了研究.我们首先研究了MORUS-640-128的完全性,得到算法输出密钥流和内部状态达到完全性的步数下界分别为4步和6步.利用此性质,我们对3步简化版MORUS-640-128进行了差分-区分攻击和密钥分割攻击.其中,差分-区分攻击仅需2个选择IV就能以0.999985的区分优势完成攻击;密钥分割攻击需要110个选择IV,能以99.8%的成功率恢复全部128比特初始密钥,计算复杂度为O(2106.8).结合完全性算法,本文提出了改进的差分自动推演算法,并对4步简化版MORUS-640-128进行了差分-区分攻击,攻击所需的数据量和区分优势分别为2105和0.999665.上述攻击均是首次针对MORUS算法的安全性分析结果,对其初始化过程的设计有一定的参考意义. 展开更多
关键词 CAESAR竞赛 MORUS算法 混乱 扩散 完全性 差分分析
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A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L. 认领 引用 被引量:2
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作者 Wei Fu Yong Fang Lei +2 位作者 Ya Ling Cai Dao Nian Zhou Jin Lan Ruan 《Chinese Chemical Letters》 SCIE CAS 2010年第7期821-823,共3页
A new alkylene dihydrofuran glycoside(1)was isolated from the root bark ofMorus alba L.,along with moracin M-3′-O-β-D-glucopyranoside(2),and moracin M-6,3′-di-O-β-D-glucopyranoside(3).Compound 1 was identified as ... A new alkylene dihydrofuran glycoside(1)was isolated from the root bark ofMorus alba L.,along with moracin M-3′-O-β-D-glucopyranoside(2),and moracin M-6,3′-di-O-β-D-glucopyranoside(3).Compound 1 was identified as 2-methylene-3-methoxy-2,5-dihydrofuran-4-O-β-D-glucopyranoside on the basis of chemical and spectroscopic data including 1D and 2D NMR spectral analysis.In addition,the antioxidant activity of 1 was evaluated using the 1,1-diphenyl-2-picrylhydrazyl(DPPH)and 2,2′-azinobis-3-ethylbenzothiazoline-6-sulphonic acid(ABTS)assay.The IC50values were 2.49 and 0.45 mg/mL,respectively. 展开更多
关键词 Morus alba L. Dihydrofuran glycoside Spectral analysis Antioxidation activity
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A new prenylated arylbenzofuran derivative from Morus alba L. 认领 引用 被引量:3
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作者 Tian, Hai Ying He, Xi +5 位作者 Zeng, Guang Yao Tan, Jian Bin Shuang, Fu Liu, Guo Ru Tan, Gui Shan Zhou, Ying Jun 《Chinese Chemical Letters》 SCIE CAS 2010年第3期329-331,共3页
2-[3,5-Di-O-β-D-glucosyl-4-(3-methylbut-2-enyl)phenyl]benzofuran-6-ol,a new prenylated arylbenzofuran derivative was isolated from Morus alba L.Its structure was elucidated by various spectroscopic methods including ... 2-[3,5-Di-O-β-D-glucosyl-4-(3-methylbut-2-enyl)phenyl]benzofuran-6-ol,a new prenylated arylbenzofuran derivative was isolated from Morus alba L.Its structure was elucidated by various spectroscopic methods including MS,~1H NMR,13C NMR,DEPT,~1H-~1HCOSY,HMQC and HMBC. 展开更多
关键词 Morus alba L. Prenylated arylbenzofuran 2-[3 5-Di-O-β-D-glu-4-(3-methylbut-2-enyl)phenyl]benzofuran-6-ol
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故障模型下MORUS算法的差分扩散性质研究 认领 引用 被引量:2
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作者 施泰荣 关杰 +1 位作者 李俊志 王森鹏 《软件学报》 EI CSCD 北大核心 2018年第9期2861-2873,共13页
MORUS算法是由H.Wu等人设计的一类认证加密算法,目前已顺利进入CAESAR竞赛第3轮竞选.研究MORUS算法故障模型下的差分扩散性质.采用面向比特的随机故障模型,结合差分分析技术与中间相遇思想,改进了针对MORUS算法的差分链搜索算法.运用该... MORUS算法是由H.Wu等人设计的一类认证加密算法,目前已顺利进入CAESAR竞赛第3轮竞选.研究MORUS算法故障模型下的差分扩散性质.采用面向比特的随机故障模型,结合差分分析技术与中间相遇思想,改进了针对MORUS算法的差分链搜索算法.运用该算法找到了5步概率为2-85的差分链,从而实现了对初始化过程5步的简化版MORUS-640-128算法的差分-区分攻击,攻击所需的数据量和区分优势分别为289和0.99965.最后,利用差分故障分析方法对认证过程3步的简化版MORUS-640-128算法进行了伪造攻击. 展开更多
关键词 CAESAR竞赛 MORUS算法 差分故障分析 中间相遇
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Composition of Essential Oils of Morus alba Leaves and Chamaecyparis pisifera Outer Heartwood 认领 引用 被引量:2
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作者 刘志明 王海英 +2 位作者 王芳 潘晓星 田补 《Agricultural Science & Technology》 CAS 2010年第8期7-9,共3页
[Objective] The aim was to explore the composition of essential oils of Morus alba leaves and Chamaecyparis pisifera outer heartwood. [Method] The essential oils of M. alba leaves and C. pisifera outer heartwood were ... [Objective] The aim was to explore the composition of essential oils of Morus alba leaves and Chamaecyparis pisifera outer heartwood. [Method] The essential oils of M. alba leaves and C. pisifera outer heartwood were analyzed by gas chromatography-mass spectrometry,respectively. [Result] Alcohols [phytol (59.47%,extracted 3 h for M. alba leaves),α-cadinol (38.77%,extracted 6 h for C. pisifera outer heartwood)] were their first principal volatile components. Phytol was usually used as pharmaceutical raw material and α-cadinol was a kind of active organic compound with antibacterial function. [Conclusion] The essential oils of M. alba leaves and C. pisifera outer heartwood with hydrodistillation have medicinal value. 展开更多
关键词 Morus alba Chamaecyparis pisifera Essential oil Gas chromatography-mass spectrometry
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Selection and characterisation of lactic acid bacteria isolated from different origins for ensiling Robinia pseudoacacia and Morus alba L.leaves 认领 引用 被引量:2
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作者 NI Kui-kui YANG Hui-xiao +2 位作者 HUA Wei WANG Yan-ping PANG Hui-li 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2016年第10期2353-2362,共10页
The objective of this study was to isolate lactic acid bacteria(LAB) strains from different origins and to select the best strains for ensiling Robinia pseudoacacia(RB) and Morus alba L.(MB)leaves. The LAB strai... The objective of this study was to isolate lactic acid bacteria(LAB) strains from different origins and to select the best strains for ensiling Robinia pseudoacacia(RB) and Morus alba L.(MB)leaves. The LAB strains were inoculated into the extracted liquid obtained from RB and MB leaves to evaluate the fermentation products. 11 LAB strains were selected for further experiments based on the highest products of lactic or acetic acid, including 1 strain of Weissella confusa, 2 of Lactobacillus reuteri and 8 of Lactobacillus plantarum.The API 50 CH fermentation experiment indicated that all of the selected 11 LAB strains utilised most of the carbohydrates. All the strains grew at temperatures between 10 and 45℃ and at a p H of 3.5 to 4.5; however, L. reuteri F7 and F8 tolerated a p H as low as 3.0. All 11 LAB strains showed antibacterial activity against Listeria monocytogens, Escherichia coil, Salmonella sp. and Acetobacter pasteurianus; however, after excluding the effect of organic acids, only F7 and F8 still exhibited antibacterial activity. The present study indicated that the selected 11 LAB strains could be used to prepare silages of RB and MB leaves, especially L. reuteri F7 and F8. 展开更多
关键词 lactic acid bacteria Morus alba L Robinia pseudoacacia silage
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Analysis of Active Components of Hexane Extractives of Morus alba Leaves 认领 引用 被引量:2
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作者 刘志明 王海英 张爽 《Agricultural Science & Technology》 CAS 2011年第1期23-25,共3页
[Objective]The aim was to explore the active compound of Morus alba leaves with the analysis of active components of hexane extractives of M.alba leaves.[Method]Antibacterial assays of hexane extractives of M.alba lea... [Objective]The aim was to explore the active compound of Morus alba leaves with the analysis of active components of hexane extractives of M.alba leaves.[Method]Antibacterial assays of hexane extractives of M.alba leaves were done and the volatile components of hexane extractives of M.alba leaves with the strongest antibacterial activity were analyzed by gas chromatography-mass spectrometry(GC-MS).[Result]The results of inhibitory effect of hexane extractives of M.alba leaves on Staphylococcus aureus and Escherichia coli showed that hexane extractives of M.alba leaves collected in June,July and August had antibacterial activity against S.aureus and had no antibacterial effect against E.coli.Furthermore,hexane extractives of M.alba leaves collected in June had the strongest antibacterial activity against S.aureus(inhibition diameter 10.95 mm).The hexane extractives of M.alba leaves collected in June was analyzed by GC-MS,the main volatile components were tetradecane(16.76%),dodecane(13.20%),diisobutyl phthalate(10.26%),decane(9.10%),hexadecane(8.71%),linolenyl alcohol(7.25%),octadecane(5.88%),eicosane(3.26%),dibutyl phthalate(2.59%).[Conclusion]Linolenyl alcohol was the potential antibacterial compound. 展开更多
关键词 Morus alba Hexane extractives Active components Linolenyl alcohol Gas chromatography-mass spectrometry
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A New Diels-Alder Type Adduct and a New Flavone from the Stem and Root Bark of Morus mongolica 认领 引用 被引量:4
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作者 Jie KANG Ruo Yun CHEN De Quan YU 《Chinese Chemical Letters》 SCIE CAS 2005年第11期1474-1476,共3页
A new Diels-Alder type adduct mongolicin G (1) and a new flavone 5'-(1", 1"-dimethylallyl)-5,7,2',4'-tetrahydroxyflavone (2) were isolated from the stem and root bark of Morus mongolica. Their structures we... A new Diels-Alder type adduct mongolicin G (1) and a new flavone 5'-(1", 1"-dimethylallyl)-5,7,2',4'-tetrahydroxyflavone (2) were isolated from the stem and root bark of Morus mongolica. Their structures were determined by spectroscopic analysis and chiroptical methods. 展开更多
关键词 Morus mongolica Diels-Alder type adduct mongolicin G flavone 5'-(1",1"-dimethylallyl)-5,7,2',4'-tetrahydroxyflavone.
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滇桑Morus yunnanensts Koidz的特征、分布与系统位置 认领 引用 被引量:3
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作者 刘凯旋 陈仁芳 +2 位作者 刘玲 柯皓天 吕银 《四川蚕业》 2015年第3期43-44,共2页
滇桑Morus yunnanensis主要分布于云南德钦、福贡、思茅、景东、贡山、新平哀牢山、屏边大围山,四川康定、攀枝花、盐源、丹巴、康定、稻城,贵州罗甸、兴仁,西藏察隅等狭窄区域,海拔1420~3800m,对高山湿度有特别要求。根据地理分布,滇... 滇桑Morus yunnanensis主要分布于云南德钦、福贡、思茅、景东、贡山、新平哀牢山、屏边大围山,四川康定、攀枝花、盐源、丹巴、康定、稻城,贵州罗甸、兴仁,西藏察隅等狭窄区域,海拔1420~3800m,对高山湿度有特别要求。根据地理分布,滇桑应是较进化类型。支持Koidz.滇桑以种级单位分出。滇桑的系统位置还需进一步研究。 展开更多
关键词 滇桑Morus yunnanensis 特征 分布 系统位置
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MORUS算法的抗碰撞性分析 认领 引用
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作者 关杰 施泰荣 +1 位作者 李俊志 张沛 《电子与信息学报》 EI CAS CSCD 北大核心 2017年第7期1704-1710,共7页
MORUS算法是CAESAR竞赛第3轮的候选认证加密算法之一,该文评估了MORUS-640-128算法对碰撞攻击的安全性。由碰撞关系确定一系列非线性方程,采用分块分析的方法,从非线性方程中找到消息字差分间的信息泄漏规律,首次给出了算法在两步后发... MORUS算法是CAESAR竞赛第3轮的候选认证加密算法之一,该文评估了MORUS-640-128算法对碰撞攻击的安全性。由碰撞关系确定一系列非线性方程,采用分块分析的方法,从非线性方程中找到消息字差分间的信息泄漏规律,首次给出了算法在两步后发生碰撞的必要条件集,确定了输入差分的字分布情况。在此基础上,将碰撞的必要条件转化成伪布尔函数最优化问题,利用混合整数规划模型进行求解。实验结果显示算法发生碰撞时,输入差的汉明重量至少为28,其碰撞概率小于1402-,得到了比文献[7]更紧致的概率上界(原为1302-)。结果表明MORUS-640-128算法具备良好的抗碰撞攻击能力。 展开更多
关键词 CAESAR竞赛 MORUS算法 碰撞攻击 差分重量下界
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A new benzofuranolignan and a new flavonol derivative from the stem of Morus australis 认领 引用
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作者 Qing Jian Zhang Di Zao Li +1 位作者 Ruo Yun Chen De Quan Yu 《Chinese Chemical Letters》 SCIE CAS 2008年第2期196-198,共3页
A new benzofuranolignan austrafuran A(1)and a new flavonol derivative 5,7,2′,4′-tetrahydroxy-3-methoxyflavone(2)were isolated from the stem of Morus australis.Their structures were determined on the basis of spectro... A new benzofuranolignan austrafuran A(1)and a new flavonol derivative 5,7,2′,4′-tetrahydroxy-3-methoxyflavone(2)were isolated from the stem of Morus australis.Their structures were determined on the basis of spectroscopic evidences. 展开更多
关键词 Morus australis Austrafuran A Flavonol Stilbenoid
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MORUS-1280-128算法的区分分析 认领 引用
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作者 郑秀林 宋海燕 付伊鹏 《计算机科学》 CSCD 北大核心 2018年第4期152-156,共5页
MORUS算法是被提交到CAESAR竞赛中的一种认证加密算法,已经进入第三轮安全评估。对算法进行区分分析对于其安全性评估具有很重要的意义。以MORUS-1280-128为例,在nonce重用的情况下,对算法进行区分分析能够区分出密文的绝大部分比特,并... MORUS算法是被提交到CAESAR竞赛中的一种认证加密算法,已经进入第三轮安全评估。对算法进行区分分析对于其安全性评估具有很重要的意义。以MORUS-1280-128为例,在nonce重用的情况下,对算法进行区分分析能够区分出密文的绝大部分比特,并通过寻找内部状态碰撞对算法进行标签伪造攻击。该研究结果对MORUS算法的安全性分析有很重要的意义。 展开更多
关键词 认证加密 MORUS算法 区分分析 伪造攻击
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对简化版MORUS算法的改进动态立方攻击 认领 引用
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作者 李俊志 关杰 《软件学报》 EI CSCD 北大核心 2020年第6期1829-1838,共10页
MORUS算法是Wu等人设计的认证加密算法,现已进入CAESAR竞赛的第三轮.动态立方攻击是Dinur等人2011年提出的针对迭代型序列密码的分析方法.提出了一种改进的动态立方攻击方法,优化了动态立方攻击的立方集合的选取规则,提出了优先猜测关... MORUS算法是Wu等人设计的认证加密算法,现已进入CAESAR竞赛的第三轮.动态立方攻击是Dinur等人2011年提出的针对迭代型序列密码的分析方法.提出了一种改进的动态立方攻击方法,优化了动态立方攻击的立方集合的选取规则,提出了优先猜测关键值并恢复相应的关键秘密信息的方法,据此给出了成功率更高的秘密信息恢复方法.利用该方法分析了初始化5步的简化版MORUS算法,最终以O(295.05)的复杂度恢复所有128比特密钥,攻击的成功率大于92%. 展开更多
关键词 MORUS 动态立方攻击 认证加密 流密码 CAESAR
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