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Carbon nanomaterials:Revolutionizing biomedical applications with promising potential 认领 引用 被引量：1
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作者 Nandhini Jayaprakash Karthikeyan Elumalai +2 位作者 Sheela Manickam Gokulakannan Bakthavatchalam Pavithra Tamilselvan 《Nano Materials Science》 EI CAS CSCD 2026年第4期801-816,共16页
Carbon-based nanomaterials(CBNs)such as fullerene,nanodiamonds,carbon nanotubes(CNTs),graphene,and carbon dots possess remarkable characteristics that render new horizons for biomedical advancements.This review examin... Carbon-based nanomaterials(CBNs)such as fullerene,nanodiamonds,carbon nanotubes(CNTs),graphene,and carbon dots possess remarkable characteristics that render new horizons for biomedical advancements.This review examines the distinctive characteristics and preparation methods highlighting their impact on the materials'functionality.Various biomedical applications of CBNs have been reported,including drug delivery,wound healing,biosensing,bio-imaging,tissue engineering,and anti-cancer.The current clinical status,biocompatibility,and toxicity of CBNs are discussed,highlighting challenges and future perspectives in regulatory and scalability aspects.This comprehensive overview aims to advance understanding and foster further research in this promising field.Through an exegesis of the various features and facets of CBNs,this review hopes to give a comprehensive perspective on the transformative possibilities of CBNs in biomedical innovations and forecast further study and innovation in this emerging field. 展开更多
关键词 Carbon nanomaterials Biomedical Fullerene Carbon nanotube Carbon dots And graphene
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Recent Advances in Hafnium Oxide Nanomaterials:From Controlled Synthesis,Structure,and Surface Engineering to Biomedical Applications 认领 引用
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作者 Mothana Hussein Tarawneh Mohammed Ali Dheyab +6 位作者 Azhar Abdul Rahman Mutaz Mohammad Alsardi Azlan Abdul Aziz Saleh T.Alanezi Wesam Abdullah Sara Abdulwahab Mehran Ghasemlou 《Rare Metals》 SCIE EI CAS CSCD 2026年第4期170-212,共43页
Hafnium oxide(HfO2)nanoparticles(NPs),derived from a rare-metal element,have gained increasing attention as a versatile class of functional nanostructures with unique optical,dielectric,and surface properties that ... Hafnium oxide(HfO2)nanoparticles(NPs),derived from a rare-metal element,have gained increasing attention as a versatile class of functional nanostructures with unique optical,dielectric,and surface properties that enable diverse biomedical applications.As a representative rare-metal oxide,HfO2 NPs with well-defined architectures offer advantageous features such as a high atomic number,chemical inertness,tunable morphology,biocompatibility,and exceptional stability for integration with other functional materials.Significant advances have been achieved in controlling crystalline phases,improving scalability,and tailoring optoelectronic and surface characteristics.However,their exploration in biomedical fields remains limited and fragmented.This review discusses the key principles of controlled synthesis,interfacial functionalization,and toxicity evaluation of HfO2 NPs.Emphasis is placed on their emerging biomedical applications,including bioimaging,radiosensitization,drug delivery,and multimodal theranostic integration.Attention is also given to hybrid systems combining HfO2 NPs with polymers,metal oxides,metal-organic frameworks,and two-dimensional nanomaterials,where interfacial synergies underpin enhanced therapeutic efficacy,diagnostic contrast,and safety.Finally,this review concludes with challenges,opportunities,and future directions,proposing strategies to establish reproducible,scalable,and high-performance rare-metal oxide platforms for nextgeneration biomedical and functional technologies.It aims to provide a comprehensive roadmap linking the synthesis,properties,and applications of HfO2 nanomaterials,positioning them as a model rare-metal oxide system to bridge the gap between nanomaterial design and clinical translation in nanomedicine. 展开更多
关键词 bioimaging biomedical applications hafnium oxide nanomaterials hybrid nanomaterials surface functionalization theranostics
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How do nanomaterials influence the spread of antibiotic resistance genes in aquatic environments? 认领 引用 被引量：1
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作者 Yun Bai Shengnan Li Shih-Hsin Ho 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第1期186-197,共12页
Antibiotic resistance genes(ARGs) are recognized as a primary threat to the sustainability of environment and human health in the 21st century.Nanomaterials(NMs) have attracted substantial attention due to their un... Antibiotic resistance genes(ARGs) are recognized as a primary threat to the sustainability of environment and human health in the 21st century.Nanomaterials(NMs) have attracted substantial attention due to their unique dimensions and structures.Unfortunately,emerging evidence suggests that NMs may facilitate the transmission of ARGs.It is crucial to elucidate how NMs affect the evolution and dissemination of ARGs.The current review comprehensively examines the role of NMs in the widespread transmission of ARGs in aquatic environments and the underlying mechanisms involved in the process.It aims to clarify the effects and mechanisms of NMs on the horizontal gene transfer processes that are associated with ARGs,including the enhancement of cell membrane permeability,the formation of nanopores on membranes,promotion of mutagenesis,and the generation of reactive oxygen species(ROSs).Furthermore,the trade-off between the removal of ARGs and horizontal transfer has been elucidated.The review aspires to guide future research directions,advance knowledge on the implications of NMs in the field of ARGs' transmission,and provide a theoretical foundation for the development of safer and more effective applications of NMs. 展开更多
关键词 Antibiotic resistance genes Antibiotic resistance bacteria Nanomaterials Horizontal gene transfer Aquatic environments
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A review on innovations in antimicrobial nanotechnology:Integrating silver nanoparticles and carbon nanomaterials 认领 引用
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作者 Khalil Ullah Hui Yan +3 位作者 Yuanyuan Shao Hui Zhang Haiping Zhang Jesse Zhu 《Particuology》 SCIE EI CAS CSCD 2026年第7期164-185,共22页
The development of advanced antibacterial agents has been significantly accelerated by nanotechnology.Particular attention is directed at Silver Nanoparticles(AgNPs)and carbon nanomaterials(CNMs)that have great potent... The development of advanced antibacterial agents has been significantly accelerated by nanotechnology.Particular attention is directed at Silver Nanoparticles(AgNPs)and carbon nanomaterials(CNMs)that have great potential.AgNPs are valued for their broad-spectrum antimicrobial activity,high biocompatibility,and ease of synthesis.In parallel,CNMs,including graphene,carbon nanotubes and carbon dots are favorable for their exceptional mechanical strength,high specific surface area,and a unique physical mechanism for disrupting microbial membranes.More recently,synergistic integration of AgNPs and CNMs into hybrid materials has emerged as a cutting-edge strategy that encourages synergies in antibacterial activity.This study presents a design-oriented,mechanism-driven analysis of CNMs@AgNPs systems by systematically linking carbon nanomaterial type,composite architecture,antibacterial mechanisms,and application relevance.These nanocomposites exhibit enhanced stability,controlled release of silver ions,and superior antibacterial effects,even to those against drug-resistant pathogens.The research is systematically examining the recent advances in CNMs@AgNPs hybrids,with a special focus on their synthesis strategies,structure characterization,antibacterial activity and mechanism,and their prospective applications in medicinal,environmental,and industrial sectors.The review paper further addresses the critical challenges and environmental impact surrounding the use of antimicrobial nanoparticles to guide the future research and development of safe,effective antimicrobial nanoparticles. 展开更多
关键词 Nanotechnology Hybrid nanocomposites Antibacterial activity Silver Carbon nanomaterials
Recent advances in nanomaterial-based optical biosensors and their biomedical and biopharmaceutical applications 认领 引用
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作者 Mengjia Xu Lutfun Nahar +5 位作者 Kenneth J.Ritchie Chenxu Wang Li Cheng Zimiao Wu Satyajit D.Sarker Mingquan Guo 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2026年第1期54-75,共22页
Optical biosensors are gaining popularity owing to their portability,miniaturization,no requirement for additional attachments,and rapid responsiveness.These features render them suitable for various applications incl... Optical biosensors are gaining popularity owing to their portability,miniaturization,no requirement for additional attachments,and rapid responsiveness.These features render them suitable for various applications including at-home diagnostics,pharmacology,and continuous molecular monitoring.The integration of functionalized low-dimensional nanomaterials(zero-dimensional(0D),1D,2D,and 3D)has redirected focus towards the design,fabrication,and optimization of optical biosensors.This review summarizes the fundamental mechanisms underlying optical biosensing.The key mechanisms include localized surface plasmon resonance(LSPR),photoluminescence(PL),surface enhancement Raman scattering(SERS),nanozyme-based colorimetric strategies,chemiluminescence,bioluminescence,and electrochemiluminescence.The advantages of various low-dimensional nanomaterials for different types of optical biosensors are presented.This comparison emphasizes their potential superiority in targeted biosensing applications.Therefore,promoting optical biosensing techniques and recent developments in advanced biosensing strategies for biomedical research and biopharmaceutical applications are necessary to establish their future directions. 展开更多
关键词 Optical biosensors Low-dimensional nanomaterials Fundamental mechanisms for biosensing At-home diagnostics Continuous molecular monitoring Biopharmaceutical applications
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Facet modulation promotes synergy between TiO2 nanomaterials and dissolved organic matter in photocatalytic generation of reactive oxygen species 认领 引用
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作者 Qianwu Wang Fangru He +4 位作者 Yaqi Liu Jingxiang Low Chuanjia Jiang Tong Zhang Wei Chen 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第7期253-260,共8页
The efficiency of reactive oxygen species(ROS)generation is the most critical factor controlling the performance of photocatalytic water treatment.Dissolved organic matter(DOM),a ubiquitous and photoedox-active consti... The efficiency of reactive oxygen species(ROS)generation is the most critical factor controlling the performance of photocatalytic water treatment.Dissolved organic matter(DOM),a ubiquitous and photoedox-active constituent in natural and waste waters,may significantly interfere with the rate and pathways of ROS generation.Here,we show that modulating exposed facets of nano-catalysts to regulate the interactions between DOM and nanomaterials can boost ROS production.Specifically,electron paramagnetic resonance spectroscopy and probe test demonstrate that the production rate of superoxide radical anion(O2•-)in a system containing{001}-faceted TiO2nanocrystals and humic/fulvic acid far exceeds those in the systems containing TiO2or DOM alone.In comparison,the synergy between{101}-faceted nano-TiO2and humic/fulvic acid is much less prominent.Enhanced production of singlet oxygen(1O2)is also observed for{001}-faceted nano-TiO2in the presence of DOM,whereas 1O2production by{101}-faceted TiO2is subdued by DOM.Moreover,the{001}-faceted material is much more robust against the inhibition effect of DOM on hydroxyl radical(•OH)production.Thermogravimetric analysis reveals distinct DOM adsorption capacities between the materials.By spectroscopic and electrochemical analyses,we further elucidate the structure-activity relationship between exposed facets and rate-limiting factors in ROS generation.Exposed facets regulate the specific mode of interaction between TiO2 and DOM,which subsequently determines the charge carrier separation,adsorption of O2,as well as quenching of photogenerated holes and ROS.The findings provide deeper insights for improving the efficacy of photocatalytic water treatment through facet engineering of semiconductors. 展开更多
关键词 Facet modulation Reactive oxygen species Photocatalytic water treatment Nanomaterials Dissolved organic matter
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Nanomaterial strategies for mitigating protein misfolding and neuroinflammation in neurodegenerative diseases 认领 引用
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作者 Yu-He Wang Xiao-Ling Lang Xiu-Li Qing 《Zoological Research》 SCIE CSCD 2026年第1期155-187,共33页
Neurodegenerative disorders such as Alzheimer's disease are characterized by pathological protein misfolding,persistent neuroinflammation,and progressive synaptic deterioration.Nanoscale therapeutic platforms offe... Neurodegenerative disorders such as Alzheimer's disease are characterized by pathological protein misfolding,persistent neuroinflammation,and progressive synaptic deterioration.Nanoscale therapeutic platforms offer a versatile strategy for simultaneously suppressing pathogenic protein aggregation and modulating glial hyperactivation,thereby addressing the multifactorial nature of neurodegenerative pathology.Engineered Au NPs,carbon-based nanodots,and related constructs with negatively charged surfaces exhibit high affinity for amyloidogenic peptides,thereby limiting amyloid-β or tau fibrillization,while photothermal strategies using graphene or gold nanorods induce localized thermal disruption of preformed aggregates,enhancing their disassembly.In parallel,functionalized nanocarriers facilitate braintargeted delivery of anti-inflammatory agents by leveraging receptor-mediated transcytosis or biomimetic cell membrane-camouflaging strategies,attenuating proinflammatory cytokines and promoting autophagic clearance.In vitro and in vivo models demonstrate integrated therapeutic benefits,including attenuation of plaque deposition,preservation of neuronal integrity,and recovery of cognitive performance.Despite remaining challenges in large-scale synthesis and long-term safety,evolving nanotechnologies offer a flexible and integrated platform capable of disrupting the pathogenic cycle linking protein misfolding,neuroinflammation,and disease progression. 展开更多
关键词 Nanomaterial Protein misfolding Neuroinflammation Alzheimer’s disease
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Bioactive Nanomaterials for Cancer Immunotherapy 认领 引用
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作者 Zhan-Zhan Zhang Kai-Jia Liu +1 位作者 Qiu-Shi Li Yang Liu 《Chinese Journal of Polymer Science》 SCIE EI CAS CSCD 2026年第7期1984-2001,共18页
Cancer immunotherapy has revolutionized oncology by harnessing the immune system to recognize and eliminate malignant cells,yet its clinical efficacy is often limited by tumor immune evasion,low immunogenicity,and an ... Cancer immunotherapy has revolutionized oncology by harnessing the immune system to recognize and eliminate malignant cells,yet its clinical efficacy is often limited by tumor immune evasion,low immunogenicity,and an immunosuppressive tumor microenvironment(TME).Recent advances in nanotechnology offer opportunities to overcome these barriers by precisely modulating both tumor and immune landscapes.In this review,we summarize three representative strategies developed by our group:(i)surface-adaptive nanomaterials(SANs),which respond dynamically to physiological and tumor-specific cues to enable prolonged systemic circulation,efficient barrier translocation,and controlled intratumoral activation;(ii)antigen-engineering nanoplatforms,designed to enhance tumor immunogenicity via delivering exogenous antigens to antigen-presenting cells(APCs),inducing tumor cells to re-express or re-generate,or anchoring immunogenic epitopes onto tumor surfaces,thereby promoting T cell activation and converting“cold”tumors into“hot”ones;and(iii)TME-modulating nanomaterials,which alleviate immune suppression via targeted delivery of inhibitors,neutralization or degradation of suppressive cytokines,and gene-level reprogramming of tumors to restore effector immunity.Together,these approaches provide a multifaceted framework for reinvigorating antitumor immune responses and offer mechanistic insights and design principles for the next generation of bioactive polymeric nanomaterials with potential translational application in cancer immunotherapy. 展开更多
关键词 Bioactive nanomaterials Cancer immunotherapy Low immunogenicity Immunosuppressive tumor microenvironment(TME) Physiological barriers
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Nanomaterial-Mediated Modulation of Plant Functional Traits and Rhizosphere Processes:Mechanistic Insights into Plant Stress Physiology 认领 引用
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作者 Abdul Ghafoor Muhammad Munir +3 位作者 Khalid Turk Muhammad Tahir Umair Riaz Adnan Mustafa 《Phyton-International Journal of Experimental Botany》 SCIE 2026年第5期34-79,共46页
Agricultural systems increasingly face interacting abiotic and biotic stresses driven by climate change and soil degradation.Plant performance under such conditions is determined by coordinated networks of functional ... Agricultural systems increasingly face interacting abiotic and biotic stresses driven by climate change and soil degradation.Plant performance under such conditions is determined by coordinated networks of functional traits governing resource acquisition,allocation,and defense.These traits also structure plant-associated microbiomes,whose activities influence nutrient cycling,stress buffering,and disease suppression.This review synthesizes current evidence that agricultural nanomaterials enhance crop stress resilience primarily by reprogramming plant functional trait networks and,through them,modulating microbiome dynamics.We analyze how nanomaterial physicochemical properties including size,surface chemistry,dissolution behavior,and redox activity determine their bioavailability and interaction with plant tissues.These interactions influence key trait categories such as root architecture,hydraulic regulation,nutrient acquisition efficiency,photosynthetic performance,and antioxidant capacity.Trait-level modulation underpins improved tolerance to drought,salinity,temperature extremes,heavy metal toxicity,and pathogen pressure.Furthermore,nanomaterial-induced shifts in plant traits reshape rhizosphere and endophytic niches,reinforcing beneficial microbial functions including nutrient mobilization,hormone regulation,pathogen suppression,and soil structural stabilization.This review proposes a trait-centric framework in which nanomaterials act as regulators of plant functional organization rather than simple growth stimulants.Future research should prioritize trait-based screening,microbiome functional monitoring,and predictive nano–ecological modeling to enable safer and more effective nanotechnology deployment for sustainable crop production. 展开更多
关键词 Nanomaterials plant functional traits plant–microbiome interactions stress resilience rhizosphere microbiome
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Nanomaterials:An innovative integrative paradigm for hepatocellular carcinoma adjuvant treatment 认领 引用
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作者 Qingqing Yang Wen Zhang +3 位作者 Keqin Ji Zhuo Wang Jie Gao Jin Ding 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS CSCD 2026年第3期4-34,共31页
This review systematically examines the application of nanomaterials in adjuvant therapy for hepatocellular carcinoma(HCC)following surgical resection,with the aim of synergistically inhibiting tumor recurrence and dr... This review systematically examines the application of nanomaterials in adjuvant therapy for hepatocellular carcinoma(HCC)following surgical resection,with the aim of synergistically inhibiting tumor recurrence and driving functional liver regeneration via a 3R paradigm(removing residual tumor cells;remodeling the immune microenvironment;and repairing liver function).This article begins by analyzing the clinical challenges associated with treating HCC on the basis of global epidemiological data and the molecular characteristics of residual micrometastases after surgery.The concept of“precision space-time intervention"is then introduced,and the design strategies and clinical development of nanomaterials are explored,including targeting,biomimetic,sustained release and degradable designs.Furthermore,this review focuses on the postresection imbalance between tumor recurrence and tissue regeneration in the HCC microenvironment,elucidating the multiscale regulatory mechanisms of liver repair,such as cell differentiation,angiogenesis regulation,maintenance of the cellular redox balance,metabolic reprogramming,and modulation of the inflammatory microenvironment.The temporal dynamics of these mechanisms are emphasized,and the pivotal role of nanomaterials in this context is clarified.The key findings of this review indicate that a multimodal platform with nanomaterials as functional units can integrate diagnosis,hemostasis,antitumor activity and regeneration promotion,thereby overcoming the limitations of monotherapy,which cannot effectively cover the entire process of liver repair.This review breaks through the static intervention model of traditional adjuvant therapy,providing theoretical evidence for the development of multimodal sequential therapeutic nanoplatforms and outlining a clinical translation pathway from the validation ofmolecular mechanisms to GMP-standard production. 展开更多
关键词 Nanomaterials Hepatocellular carcinoma Postoperative adjuvant therapy Liver regeneration Multimodal nanoplatforms
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Transformative role of Pr3+in ferrite nanomaterials:A review on magnetic tuning and structural optimization for advanced technologies 认领 引用
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作者 Sonia Chalia Manish Naagar +2 位作者 Fayu Wan Preeti Thakur Atul Thakur 《Journal of Rare Earths》 SCIE EI CAS CSCD 2026年第4期969-987,I0001,共19页
Ferrite nanomaterials have garnered significant interest due to their exceptional magnetic,electrical,and thermal properties,making them indispensable in high-frequency electronics,data storage,biomedical applications... Ferrite nanomaterials have garnered significant interest due to their exceptional magnetic,electrical,and thermal properties,making them indispensable in high-frequency electronics,data storage,biomedical applications,and electromagnetic shielding.This review provides a comprehensive analysis of the transformative role of praseodymium(Pr3+)as a dopant in ferrite nanomaterials,emphasizing its impact on structural modifications,magnetic behavior,and technological advancements.The incorporation of Pr3+ions induces lattice distortions,alters cation distribution,and enhances magnetocrystalline anisotropy,resulting in tunable coercivity,saturation magnetization,and Curie temperature.Systematic investigations reveal that Pr3+doping improves structural stability by suppressing oxygen vacancies and minimizing secondary phase formation while simultaneously influencing grain size,morphology,and phase purity.The tailored magnetic properties achieved through Pr3+substitution enhance performance in applications such as high-density magnetic storage,targeted drug delivery,magnetic hyperthermia,and microwave absorption.Furthermore,this review highlights promising research directions,including dopant concentration optimization,advancements in synthesis techniques,and the development of multifunctional Pr3+-doped ferrite nanocomposites.By bridging the gap between experimental findings and theoretical insights,this work lays a foundation for the continued exploration of rare-earth-modified ferrite nanomaterials,paving the way for next-generation functional materials with superior performance and broad application potential. 展开更多
关键词 Nanomaterials Rare earth element Praseodymium doping Coercivity Saturation magnetization Magnetic anisotropy
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Innovations in nanomaterials for remediation of heavy metal-polluted soil:Advances,mechanistic insights,and future prospects 认领 引用
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作者 Mingmin Wang Xuehao Zheng +6 位作者 Belay Tafa Oba Yebin Lin Chenbo Shen Xiong Huang Fengxia Yang Qiang Xiao Yongzhen Ding 《Nano Materials Science》 EI CAS CSCD 2026年第1期11-35,共25页
Soil contaminated with heavy metals is a global health hazard.Nanomaterials,with their unique physical and chemical properties,hold significant potential for the remediation of soil polluted with heavy metals.They eff... Soil contaminated with heavy metals is a global health hazard.Nanomaterials,with their unique physical and chemical properties,hold significant potential for the remediation of soil polluted with heavy metals.They effectively reduce the mobility and bioavailability of heavy metals through various mechanisms such as adsorption,precipitation,and oxidation-reduction.This paper provides an in-depth exploration of the cuttingedge applications of various nanomaterials,including nanometallic,nano non-metallic materials,nanoclay and mineral materials,and nano modified biochar materials,in the remediation of heavy metal-contaminated soils.It specifically focuses on the key factors influencing the remediation efficacy of these nanomaterials,as well as the underlying remediation mechanisms and methods for performance optimization.The aims of this paper are to provide guidance for the further application of nanomaterials in the field of soil heavy metal remediation,and to offer insights that could promote the effective control of soil heavy metal pollution. 展开更多
关键词 Nanomaterials Heavy metals Soil pollution Soil remediation Immobilization/passivation
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Metal-Doped Carbon-Based Nanomaterials:Photothermal Mechanism Innovation and Precision Therapy Advancement in Antibacterial and Antitumor Applications 认领 引用
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作者 Pengxiang Liu Juan Du +3 位作者 Guoqiang Ma Zheng Li Aibing Chen Senlin Hou 《Rare Metals》 SCIE EI CAS CSCD 2026年第5期28-47,共20页
Metal-doped carbon-based nanomaterials(M-CNM)play a strategically significant role in next-generation precision antibacterial and antitumor therapies,as they integrate synergistic photothermal ablation,catalytic react... Metal-doped carbon-based nanomaterials(M-CNM)play a strategically significant role in next-generation precision antibacterial and antitumor therapies,as they integrate synergistic photothermal ablation,catalytic reactive oxygen species(ROS)generation,and multimodal imaging capabilities.However,their clinical translation is hindered by unclear in vivo metabolic pathways,uncontrollable metal-ion leakage,suboptimal photothermal conversion efficiency in deep tissues,and the lack of dopant-specific efficacy-toxicity guidelines.This review elaborates the in vivo metabolic pathways and photothermal conversion mechanisms of carbon-based nanomaterials(CNM)with intrinsic photothermal properties in detail.It systematically analyzes how doping different metallic elements regulates their photothermal performance,delves into their antibacterial and antitumor efficacy,and discusses their potential applications and existing limitations in relevant therapeutic fields.This work provides unique insights into the design and construction of M-CNM in diverse biological applications,offering theoretical support for advancing their development and clinical translation in precision antibacterial and antitumor treatments,while also emphasizing the direction of future optimization to address key challenges for clinical application. 展开更多
关键词 carbon-based nanomaterials clinical translation metal-doped photothermal conversion synergistic antibacterial synergistic antitumor
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Harnessing chirality:A new dawn in inorganic nanomaterial synthesis and biomedical applications 认领 引用
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作者 Yue Pan Jing Ren +5 位作者 Yifan Sun Luying Lu Jia Gao Liping Chen Shancheng Yan Zhiyang Li 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第4期51-70,共20页
Chirality,a fundamental property of biological systems,is widely present at the molecular,cellular,and tissue levels.Current studies have shown that chiral inorganic nanomaterials,have good chiral optical activity as ... Chirality,a fundamental property of biological systems,is widely present at the molecular,cellular,and tissue levels.Current studies have shown that chiral inorganic nanomaterials,have good chiral optical activity as well as high enantioselectivity.When interacting with biological systems,the enantioselective behavior of chiral inorganic nanomaterials towards biomolecules can distinguish between different isomers of biomarkers,which,combined with the excellent optical activity of chiral inorganic nanomaterials,allows for the rapid and sensitive detection of biomarkers.Moreover,chiral inorganic nanomaterials exhibit stronger internalization and retention capabilities in cells,and by specifically targeting specific biomarkers can regulate cellular activity and catalyze related reactions,thereby achieving synergistic treatment of various diseases.In addition,chiral inorganic nanomaterials also have good biocompatibility and do not cause cell damage in living organisms.Moreover,chiral inorganic nanomaterials have programmable surfaces that can be tailored to suit specific biological functions.Due to the important role of chiral inorganic nanomaterials in the biomedical field,this paper summarizes and discusses the synthesis and biomedical applications of chiral inorganic nanomaterials.It further looks forward to its future development prospects to provide a reference for promoting relevant research on chiral inorganic nanomaterials in biomedical fields. 展开更多
关键词 Chiral inorganic nanomaterials Enantioselectivity Chiral optical properties Biomarker detection Disease therapy
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Frequency-comb-enabled ultrasensitive second-harmonic spectroscopy of surface-plasmon-enhanced ZnO nanomaterials 认领 引用
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作者 SIYI WANG CHENGLIN GU +10 位作者 DAPING LUO SIYING HE MENGLIN ZHANG XINYUE LI XINGYU LIU CHENYU LIU JIAYU WANG ZHIWEI ZHU ZEJIANG DENG BOTAO WU WENXUE LI 《Photonics Research》 SCIE EI CAS CSCD 2026年第6期2409-2417,共9页
Second-harmonic spectroscopy is a powerful tool for imaging,sensing,and in situ monitoring,with a broad range of applications in the characterization and analysis of nanomaterials.However,its sensitivity is limited by... Second-harmonic spectroscopy is a powerful tool for imaging,sensing,and in situ monitoring,with a broad range of applications in the characterization and analysis of nanomaterials.However,its sensitivity is limited by the inherently low nonlinear conversion efficiency of nanomaterials.This study demonstrates a dual-comb secondharmonic generation(SHG)platform that achieves unprecedented sensitivity through the integration of femtosecond dual-comb spectroscopy with plasmonic array-enhanced SHG from ZnO nanocrystal films.The system enables single-spectrum acquisition within 2.16μs.When combined with microscopy,the platform performs SHG distribution imaging across 16×81 spatial points within 2.8 ms of sampling time,resolving polarization-dependent features at 1.0μm spatial resolution.This high-speed,ultrasensitive spectroscopic approach enhances the detection of nanoscale optoelectronic properties. 展开更多
关键词 situ monitoringwith frequency comb ultrasensitive zno nanocrys characterization analysis ZNO nanomaterials nonlinear conversion efficiency second harmonic spectroscopy
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MSA-ConvNeXt:Predicting Magnetism of Doped Two-Dimensional Nanomaterials via Multi-Scale Convolution and Attention Mechanisms 认领 引用
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作者 Yuxuan Feng Lili Liang +1 位作者 Guanglu Sun Yanrui Wei 《Computers, Materials & Continua》 SCIE EI 2026年第9期354-368,共15页
In doped two-dimensional nanomaterials,magnetism is one of the important physical properties.By introducing foreign doping atoms or molecules,the electronic structure of the material can be effectively regulated,leadi... In doped two-dimensional nanomaterials,magnetism is one of the important physical properties.By introducing foreign doping atoms or molecules,the electronic structure of the material can be effectively regulated,leading to changes in magnetic behavior.Currently,magnetic property prediction has achieved considerable results with the help of traditional CNNs,but there are still obvious limitations:(1)The feature extraction of dopant sites is constrained by fixed receptive fields,making it difficult to characterize local structural perturbations in the vicinity of dopant atoms and their spatial influence propagating to surrounding regions;(2)CNNs lack the capability to model long-range dependencies between non-neighboring atoms and their chemical bonds,thereby weakening the representation of long-range interactions within the material.In this study,we propose Multi-Scale and Attention ConvNeXt(MSA-ConvNeXt)based on multi-scale convolution and attention mechanisms,which consists of the following two core modules:(1)The Multi-scale Convolution Attention Block(MCAB),which models local structural perturbations around dopant atoms and their spatial effects via parallelmulti-scale convolutions.It uses a serial channel and spatial attention mechanism to adaptively recalibrate multi-scale features,highlighting the response of doping related regions and enhancing the ability to express dopant-site information;(2)The Visual Geometry Group–Swin Transformer(VGG-Swin)architecture extracts structural features of dopant sites using VGG convolutions to prevent the attenuation of structural information during global relationship modeling.Subsequently,the Swin Transformer is introduced,which uses the self-attention mechanism to dynamically weight and globally associate features at different spatial locations,in order to depict the long-range correlations between non-neighboring atoms and their chemical bonds with the dopant-site.Experiments conducted on a doped two-dimensional nanomaterial dataset constructed from the CMR database demonstrate that the proposed model outperforms existing methods in terms of accuracy and F1-score.Specifically,MSA-ConvNeXt achieves an accuracy of 91.66%,representing an improvement of 1.65%over the next best model.In addition,all experimental results are averaged over multiple independent runs(with five different random seeds),demonstrating the stability and reliability of themodel’s performance.Ablation studies further validate the effectiveness of each module design. 展开更多
关键词 Doped two-dimensional nanomaterials magnetic property prediction multi-scale convolution attention mechanism ConvNeXt
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Prussian blue and its analogues nanomaterials:A focused view on physicochemical properties and precise synthesis 认领 引用 被引量：1
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作者 Yicheng Tan Duo Chen +3 位作者 Volodymyr Kotsiubynskyi Guangshe Li Laifa Shen Wei Han 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2025年第8期393-406,共14页
Prussian blue/Prussian blue analogues(PB/PBAs)are widely used in electrochemistry and materials science fields,such as electrochemical energy storage,catalysis,water purification,and electromagnetic wave absorption,ow... Prussian blue/Prussian blue analogues(PB/PBAs)are widely used in electrochemistry and materials science fields,such as electrochemical energy storage,catalysis,water purification,and electromagnetic wave absorption,owing to their 3D open-framework structure,tunable composition,and large specific surface area.However,the co-precipitation method,which is most suitable for large-scale production of PB/PBAs,often leads to the formation of numerous crystal defects and severe lattice distortion,which significantly affects the structural stability of PB/PBAs.To obtain high-crystallinity PB/PBAs with targeted properties,precise synthesis considering various detailed conditions is especially needed.Herein,this review comprehensively summarizes the fundamental structure composition,key factors in synthesis,and applications in the electrochemistry of PB/PBAs.Unlike previous reports,this review elucidates the relationship between the physicochemical properties of PB/PBAs and their structural composition,with a particular focus on revealing the mechanisms and significance of specific preparation methods during the synthesis process,including reactant concentration,chelating agent,aging,atmosphere,temperature,and drying conditions,for achieving the precise fabrication of PB/PBAs nanomaterials.As PB/PBAs gradually become materials for multidimensional applications,we urge greater attention to the unique properties of PB/PBAs that are sustained by high crystallinity and stable crystal structures.This will effectively ensure the maximization of their advantages in practical applications. 展开更多
关键词 Prussian blue Prussian blue analogue Inorganic synthesis Electrochemical energy storage Nanomaterial
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The amorphization strategies of two-dimensional transition metal oxide/(oxy)hydroxide nanomaterials for enhanced electrocatalytic water splitting 认领 引用 被引量：2
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作者 Si-Bin Duan Yu-Qing Wang +3 位作者 Rui Cao Yi-Fei Sun Wen Zhang Rong-Ming Wang 《Rare Metals》 SCIE EI CAS CSCD 2025年第2期822-840,共19页
Amorphous two-dimensional transition metal oxide/(oxy)hydroxide(2D TMO/TMHO)nanomaterials(NMs)have the properties of both 2D and amorphous materials,displaying outstanding physicochemical qualities.Therefore,they demo... Amorphous two-dimensional transition metal oxide/(oxy)hydroxide(2D TMO/TMHO)nanomaterials(NMs)have the properties of both 2D and amorphous materials,displaying outstanding physicochemical qualities.Therefore,they demonstrate considerable promise for use in electrocatalytic water splitting applications.Here,the primary amorphization strategies for achieving the 2D TMO/TMHO NMs are comprehensively reviewed,including low-temperature reaction,rapid reaction,exchange/doping effect,ligand modulation,and interfacial energy confinement.By integrating these strategies with various physicochemical synthesis methods,it is feasible to control the amorphization of TMO/TMHO NMs while maintaining the distinctive benefits of their 2D structures.Furthermore,it delves into the structural advantages of amorphous 2D TMO/TMHO NMs in electrocatalytic water splitting,particularly emphasizing recent advancements in enhancing their electrocatalytic performance through interface engineering.The challenges and potential future directions for the precise synthesis and practical application of amorphous 2D TMO/TMHO NMs are also provided.This review aims to establish a theoretical foundation and offer experimental instructions for developing effective and enduring electrocatalysts for water splitting. 展开更多
关键词 Amorphous nanomaterials 2D materials Transition metal oxide/(oxy)hydroxide Electrocatalytic water splitting
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Thiolated nanomaterials for bone tissue engineering:synthesis,mechanisms,and applications 认领 引用 被引量：1
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作者 Yi-Ning Gong Bin Zhu +4 位作者 Ya-Zhong Bu Bao-Ji Du Shi-Chang Liu Lei Luo Liang Yan 《Rare Metals》 SCIE EI CAS CSCD 2025年第7期4346-4375,共30页
Owing to their unique biological effects and physicochemical properties,nanomaterials have garnered substantial attention in the field of bone tissue engineering(BTE),targeting the repair and restoration of impaired b... Owing to their unique biological effects and physicochemical properties,nanomaterials have garnered substantial attention in the field of bone tissue engineering(BTE),targeting the repair and restoration of impaired bone tissue.In recent years,strategies for the design and optimization of nanomaterials through thiolation modification have been widely applied in BTE.This review concisely summarizes the categories of nanomaterials commonly used in BTE and focuses on various strategies for the modification of nanomaterials via thiolation.A multifaceted analysis of the mechanisms by which thiolated nanomaterials enhance nanomaterial-cell interactions,promote drug loading and release,and modulate osteogenic differentiation is presented.Furthermore,this review introduces biomedical applications of thiolated nanomaterials in BTE,including as scaffold components for bone regeneration,coatings for bone implants,and drug delivery systems.Finally,the future perspectives and challenges in the development of this field are discussed.Thiolation modification strategies provide a platform for developing new ideas and methods for designing nanomaterials for BTE and are expected to accelerate the development and clinical translation of novel bone repair materials. 展开更多
关键词 Bone tissue engineering Nanomaterials Thiolation Bone regeneration Biomedical applications
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Surface element design of nanomaterials considering surface curvature dependence 认领 引用 被引量：1
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作者 Yongchao Zhang Lian Wang +2 位作者 Fangxin Wang Bin Li Xiaofan Gou 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2025年第1期42-53,共12页
Nanomaterials have garnered recognition for their notable surface effects and demonstration of superior mechanical properties.Previous studies on the surface effects of nanomaterials,employing the finite element metho... Nanomaterials have garnered recognition for their notable surface effects and demonstration of superior mechanical properties.Previous studies on the surface effects of nanomaterials,employing the finite element method,often relied on simplified twodimensional models due to theoretical complexities.Consequently,these simplified models inadequately represent the mechanical properties of nanomaterials and fail to capture the substantial impact of surface effects,particularly the curvature dependence of nanosurfaces.This study applies the principle of minimum energy and leverages the Steigmann-Ogden surface theory of nanomaterials to formulate a novel finite element surface element that comprehensively accounts for surface effects.We conducted an analysis of the stress distribution and deformation characteristics of four typical 2D and 3D nanomaterial models.The accuracy of the developed surface element and finite element calculation method was verified through comparison with established references.The resulting finite element model provides a robust and compelling scientific approach for accurately predicting the mechanical performance of nanomaterials. 展开更多
关键词 Nanomaterials Surface effect Surface element curvature dependence Finite element method
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