期刊文献+
共找到167篇文章
< 1 2 9 >
每页显示 20 50 100
Chaos and complexity in a cardiac pacemaker model with incommensurate fractional-order dynamics:Empirical validation and cardiovascular implications 认领 引用
1
作者 Haneche Nabil Hamaizia Tayeb 《Chinese Physics B》 SCIE EI CAS CSCD 2026年第7期852-863,共12页
The dynamics of heart rhythms plays a pivotal role in physiological health,where chaotic behavior is often associated with pathological cardiac states.In this work,we investigate a fractional-order model of cardiac pa... The dynamics of heart rhythms plays a pivotal role in physiological health,where chaotic behavior is often associated with pathological cardiac states.In this work,we investigate a fractional-order model of cardiac pacemaker dynamics using incommensurate derivatives to capture the complex memory effects and non-local interactions inherent in biological systems.We demonstrate that slight variations in the fractional orders induce rich dynamics,including chaos and coexisting attractors,signifying transitions between normal and dysfunctional rhythms.Crucially,our model exhibits wider chaotic regions than classical integer-order counterparts when the incommensurate derivatives are perturbed.Furthermore,we reveal pronounced multistability,where distinct chaotic attractors coexist under identical parameters,reflecting the system's capacity for abrupt transitions between physiological and pathological states.These findings advance the mechanistic understanding of rhythm disorders and highlight the critical role of fractional calculus in modeling cardiac dynamics. 展开更多
关键词 cardiac pacemaker model incommensurate fractional-order rhythm dynamics chaos bistability
暂未订购 下载PDF
Evaluating the Impact of Different Electrocardiogram Methods on Detecting Pacemaker Dysfunction and Cardiac Function Changes in Pacemaker Patients 认领 引用
2
作者 Yan Li Chun Zhou +1 位作者 Ying Li Binlin Chen 《Journal of Clinical and Nursing Research》 2025年第8期7-13,共7页
Objective:To investigate the effect of 12-lead electrocardiogram and 24-hour dynamic electrocardiogram in detecting pacemaker dysfunction and changes in cardiac function indexes in patients with pacemaker implantation... Objective:To investigate the effect of 12-lead electrocardiogram and 24-hour dynamic electrocardiogram in detecting pacemaker dysfunction and changes in cardiac function indexes in patients with pacemaker implantation.Methods:A total of 136 patients with pacemaker implantation in the First Clinical Medical College of Three Gorges University,Institute of Cardiovascular Disease of Three Gorges University and Yicang Central People’s Hospital from January 2023 to December 2024 were selected as the research objects.All patients received 12-lead electrocardiogram and 24-hour holter 3–14 days after implantation.Results:The overall detection rate of various types of pacemaker dysfunction by Holter was significantly higher than that by conventional ECG(27.21%vs.5.15%,χ2=24.402,P<0.001).The overall arrhythmia detection rate of Holter was significantly higher than that of conventional electrocardiogram(57.35%vs.10.29%,χ2=67.277,P<0.001).The time domain indexes of heart rate variability obtained by 24-hour continuous monitoring of Holter were significantly improved compared with those of conventional electrocardiogram(P<0.05).Conclusions:Compared with 12-lead electrocardiogram,24-hour holter monitoring can more accurately detect pacemaker dysfunction and arrhythmia in patients with pacemaker implantation,and provide more comprehensive data of heart rate variability,which is helpful for clinicians to better evaluate the cardiac function of patients and adjust treatment plans. 展开更多
关键词 Pacemaker implantation Electrocardiogram Abnormal pacemaker function Cardiac arrhythmia Heart rate variability
暂未订购 下载PDF
Anti-SSA/Ro antibody-positive autoimmune myocarditis combined with complete atrioventricular block requiring implantation with a permanent pacemaker:A case report 认领 引用
3
作者 Peng-Bo Xiao Xi-Rui Yang 《World Journal of Clinical Cases》 2025年第22期79-85,共7页
BACKGROUND Autoimmune myocarditis(AM)associated with autoimmune diseases can cause complete atrioventricular block(CAVB),but the related autoantigens and the underlying mechanisms are unclear.Anti-SSA/Ro antibodies ma... BACKGROUND Autoimmune myocarditis(AM)associated with autoimmune diseases can cause complete atrioventricular block(CAVB),but the related autoantigens and the underlying mechanisms are unclear.Anti-SSA/Ro antibodies may play an important role in this process,but cases of AM with positive anti-SSA/Ro antibodies are rare.In addition,arrhythmias,such as atrioventricular block,are very common in patients with autoimmune diseases,but severe atrioventricular block requiring permanent pacemaker implantation is extremely rare.CASE SUMMARY The patient in this case had AM with anti-SSA/Ro antibody positivity,which was associated with connective tissue disease,and the patient subsequently developed CAVB.After intensive immunosuppressive therapy,the antibody test results became negative,and pulmonary hypertension significantly improved.However,the outcome of permanent pacemaker implantation did not change.CONCLUSION In clinical practice,the awareness of adult AM associated with autoimmune diseases combined with CAVB should be strengthened in clinicians,and anti-SSA/Ro antibodies may play a role in this process.Therefore,improving the detection of antibodies and early intervention,such as active immunosuppression therapy,may be very important for improving disease prognosis.For patients who do not respond to immunosuppressive therapy,implantation of a permanent pacemaker may become an essential treatment option. 展开更多
关键词 Autoimmune myocarditis Anti-SSA/Ro antibodies Connective tissue disease Permanent pacemaker Immunosuppressant Case report
暂未订购 下载PDF
Successful leadless pacemaker implantation in a patient with dextroversion of the heart:A case report 认领 引用
4
作者 Na Li Hai-Xiong Wang +1 位作者 Yue-Hui Sun Yan Shu 《World Journal of Clinical Cases》 SCIE 2023年第33期8089-8093,共5页
BACKGROUND Dextroversion is defined as the presence of dextrocardia with situs solitus,dextroloop ventricles,and normally related great arteries.Dextrocardia can pose technical challenges when interventional treatment... BACKGROUND Dextroversion is defined as the presence of dextrocardia with situs solitus,dextroloop ventricles,and normally related great arteries.Dextrocardia can pose technical challenges when interventional treatments are required.However,the challenges posed by dextroversion can be amplified due to the disruption of typical anatomical relationships,the unpredictable positioning and boundaries of cardiac structures resulting from the shift,and the pathological processes influencing rotation.CASE SUMMARY A 73-year-old woman with cardiac dextroversion suffered from a recurrence of atrial fibrillation after her radiofrequency catheter ablation and Despite the cessation of antiarrhythmic medications,there were episodes of sinus pauses and symptomatic bradycardia,with heart rates dropping as low as 28 beats per minute.CONCLUSION Dextroversion makes the implantation of leadless pacemakers more challenging,and appropriate adjustments in fluoroscope angles may be crucial for intracardiac operations.Additionally,when advancing delivery systems,attention should be paid to rotational direction during valve-crossing procedures;changes in the perspective of posture angle between normal cardiac position and dextroversion can serve as references. 展开更多
关键词 Leadless pacemaker Dextroversion Pacemaker implantation Case report
暂未订购 下载PDF
A Meta-analysis of Major Complications between Traditional Pacemakers and Leadless Pacemakers 认领 引用 被引量:1
5
作者 Diyu Cui Yimeng Liao +1 位作者 Jianlin Du Yunqing Chen 《Cardiovascular Innovations and Applications》 2021年第1期145-153,共9页
Objectives:We aim to compare the major complications between leadless pacemakers and traditional pacemakers.Background:Leadless pacemakers,which are increasingly used in clinical practice,have several advantages compa... Objectives:We aim to compare the major complications between leadless pacemakers and traditional pacemakers.Background:Leadless pacemakers,which are increasingly used in clinical practice,have several advantages compared with traditional pacemakers in avoiding pocket-and lead-related complications.However,the clinical effect of leadless pacemakers remains controversial.Methods:PubMed,Embase,the Cochrane Central Register of Controlled Trials(CENTRAL),the CNKI database,and the Wanfang database were searched from July 2013 to December 2019.Studies comparing leadless pacemakers and traditional pacemakers were included.The primary end point was major complications.The secondary end points were cardiac perforation/pericardial effusion,device revision or extraction,loss of device function,and death.Results:Six studies fulfi lled the inclusion criteria.Only four of the six studies reported data on major complications.Leadless pacemakers were associated with a lower incidence of major complications(risk ratio 0.33,95%confi dence interval 0.25–0.44,P<0.00001,I²=49%).We extracted data on cardiac perforation/pericardial effusion,device revision or extraction,loss of device function,and death from six studies.Our meta-analysis showed that leadless pacemakers have a higher risk of cardiac perforation or pericardial effusion(risk ratio 4.28,95%confi dence interval 1.66–11.08,P=0.003,I²=0%).No statistically signifi cant differences were found for mortality,device revision or extraction,and loss of device function.Conclusion:Compared with traditional pacemakers,leadless pacemakers have a signifi cantly decreased risk of major complications,but have a higher risk of cardiac perforation or pericardial effusion. 展开更多
关键词 Leadless pacemaker traditional pacemaker treatment effect complication meta-analysis
暂未订购 下载PDF
Analyses of risk factors and prognosis for new-onset atrial fibrillation in elderly patients after dual-chamber pacemaker implantation 认领 引用 被引量:6
6
作者 Xiao-Li CHEN Xue-Jun REN +3 位作者 Zhuo LIANG Zhi-Hong HAN Tao ZHANG Zhi LUO 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2018年第10期628-633,共6页
Objective To retrospectively identify risk factors and the prognosis for new-onset atrial fibrillation (AF)after implantation of dual-chamber pacemakers in elderly patients.Methods Consecutive patients aged >65year... Objective To retrospectively identify risk factors and the prognosis for new-onset atrial fibrillation (AF)after implantation of dual-chamber pacemakers in elderly patients.Methods Consecutive patients aged >65years who underwent their first implantation of a dual-chamber permanent pacemaker in Beijing Anzhen Hospital from October 2013to May 2016were enrolled.Their complete program- ming and follow-up data were recorded.Follow-up end points included new-onset AF and major adverse cardiovascular and cerebrovascular events.Restdts Altogether,322patients were enrolled,with new-onset AF observed in 79(24.5%)during their follow-up.Multivariable analysis identified four independent predictors of new-onset AF in elderly patients after pacemaker implantation:hypertension (HR =3.040, 95%CI:1.09-3.05,P =0.00),age (HR =1.966,95%CI:1.57-3.68,P =0.01);left atrial enlargement (HR =1.645,95%CI:1.05-1.25,P = 0.03);high ventricular pacing rate (HR =1.137,95%CI:1.01-1.06,P =0.01).Univariable analysis indicated that the CHA2DS2-VASc score was also a risk factor for AF (HR =1.368,95%CI:1.178-1.589,P =0.002),whereas multivariable regression analysis did not. Kaplan-Meier survival analysis showed that the risk for ischemic stroke was significantly higher in the new-onset AF group than in the non-AF group (P <0.05).Conclusion Hypertension,age,left atrial enlargement,and high ventricular pacing rate were independent predictors of new-onset AF in elderly patients after implantation of a permanent pacemaker.New-onset AF increased the risk for ischemic stroke. 展开更多
关键词 Atrial fibrillation Dual-chamber pacemaker Elderly Ischernic stroke
暂未订购 下载PDF
Dual antiplatelet therapy increases pocket hematoma complications in Chinese patients with pacemaker implantation 认领 引用 被引量:5
7
作者 Yan DAI Ke-Ping CHEN +2 位作者 Wei HUA Jing-Tao ZHANG Shu ZHANG 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2015年第4期383-387,共5页
Objective To assess the prevalence of the bleeding complications in pacemaker implanted patients receiving different antiplatelet regimens,and the influence of each regimen on hospital stays after device implantation.... Objective To assess the prevalence of the bleeding complications in pacemaker implanted patients receiving different antiplatelet regimens,and the influence of each regimen on hospital stays after device implantation.Methods We prospectively enrolled 364 patients receiving the cardiac rhythm device implantations in Fuwai Hospital from July 2012 to December 2013.Bleeding complications including pocket hematoma,hemothorax,cardiac tamponade and blood transfusion requirement were measured as endpoints.Post operation hospital stay was also included in the endpoints.Results Bleeding complications were detected in 15 patients(14 with hematoma,one with hemothorax)out of all 364 patients(4.12%).Dual antiplatelet therapy(DAT)significantly increased hematoma(19.3%)compared with aspi-fin treatment(ASA)(3.2%,P=0.001)and no antiplatelet therapy(1.9%,P〈0.001).There was no significant difference in incidence of pocket hematoma between the ASA group and the control group(P=0.45).The post procedure hospital stay was longer in DAT group(5.45±2.01 days)compared to those in the ASA group(3.65±1.37 days,P〈0.05)or control group(3.99±2.27 days,P〈0.05).Pocket hema-toma was considered an independent predictor of hospital stay prolongation(OR:5.26;95%CI:1.56-16.64;P=0.007).Conclusions Among the Chinese patients undergoing device implantation in this study,the use of dual antiplatelet agents significantly increased the risk of pocket hematoma complications and led to a longer hospital stay.Use of aspirin alone did not increase the risk. 展开更多
关键词 Complication Dual antiplatelet therapy Hematoma Pacemaker
暂未订购 下载PDF
Pacemaker therapy in very elderly patients: survival and prognostic parameters of single center experience 认领 引用 被引量:4
8
作者 Massimiliano Marini Marta Martin +6 位作者 Michela Saltori Silvia Quintarelli Filippo Zilio Fabrizio Guarracini Alessio Coser Sergio Valsecchi Roberto Bonmassari 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2019年第12期880-884,共5页
Background Permanent pacing is the therapy of choice for treating severe and/or symptomatic bradyarrhythmias. The number of very elderly patients receiving pacemakers is increasing and little is known about survival i... Background Permanent pacing is the therapy of choice for treating severe and/or symptomatic bradyarrhythmias. The number of very elderly patients receiving pacemakers is increasing and little is known about survival in this specific subgroup. This study is aimed at assessing the actual survival of patients requiring pacing therapy at age > 85 years and investigating variables associated with death. Methods Between 2010 and 2017, 572 patients aged ≥ 85 years underwent pacemaker implantation for conventional bradycardia indications in Department of Cardiology, S. Chiara Hospital, Italy. Results Thirty percent of patients were ≥ 90-year-old and comorbidities were frequent. Fifty-seven percent of patients required pacing for prognostic reasons(acquired atrioventricular block), and the remaining for relief of bradycardia symptoms. A dual-chamber pacemaker was implanted in 34% of patients. The 5-year survival was 45%(standard error: 3%), and the 8-year survival was 26%(standard error: 4%). The risk of death was similar in patients who received pacemaker for symptom relief and for prognostic reasons in the overall population(HR = 1.19, 95% CI: 0.93–1.52, P = 0.156), as well as in the ≥ 90-year-old group(HR = 1.39, 95% CI: 0.92–2.11, P = 0.102). At multivariate analysis, following variables were associated with death: higher age, lower ejection fraction, dementia/dysautonomia and diagnosis of cancer. The pacing indication and the implantation of a single chamber pacemaker were not associated with worse prognosis. Conclusions This study showed a good life expectancy in patients aged ≥ 85 years who received a pacemaker. Strong risk factors for all-cause death were non-cardiac. Pacemaker therapy seems a clinically effective therapeutic option to improve survival and to control bradyarrhythmia-related symptoms in very elderly patients. 展开更多
关键词 Mortality Pacemaker The elderly
暂未订购 下载PDF
Hwangryunhaedok-tang induces the depolarization of pacemaker potentials through 5-HT3 and 5-HT4 receptors in cultured murine small intestine interstitial cells of Cajal 认领 引用 被引量:4
9
作者 Hyun Jung Kim Guem San Lee +1 位作者 Hyungwoo Kim Byung Joo Kim 《World Journal of Gastroenterology》 SCIE CAS 2017年第29期5313-5323,共11页
AIM To investigate the effects of a water extract of Hwangryunhaedok-tang(HHTE) on the pacemaker potentials of mouse interstitial cells of Cajal(ICCs).METHODS We dissociated ICCs from small intestines and cultured. IC... AIM To investigate the effects of a water extract of Hwangryunhaedok-tang(HHTE) on the pacemaker potentials of mouse interstitial cells of Cajal(ICCs).METHODS We dissociated ICCs from small intestines and cultured. ICCs were immunologically identified using an antic-kit antibody. We used the whole-cell patch-clamp configuration to record the pacemaker potentials generated by cultured ICCs under the current clamp mode(I = 0). All experiments were performed at 30 ℃-32 ℃RESULTS HHTE dose-dependently depolarized ICC pacemaker potentials. Pretreatment with a 5-HT_3 receptor anta-gonist(Y25130) or a 5-HT_4 receptor antagonist(RS39604) blocked HHTE-induced pacemaker potential depolarizations, whereas pretreatment with a 5-HT7 receptor antagonist(SB269970) did not. Intracellular GDPβS inhibited HHTE-induced pacemaker potential depolarization and pretreatment with a Ca2+-free solution or thapsigargin abolished the pacemaker potentials. In the presence of a Ca2+-free solution or thapsigargin, HHTE did not depolarize ICC pacemaker potentials. In addition, HHTE-induced pacemaker potential depolarization was unaffected by a PKC inhibitor(calphostin C) or a Rho kinase inhibitor(Y27632). Of the four ingredients of HHT, Coptidis Rhizoma and Gardeniae Fructus more effectively inhibited pacemaker potential depolarization.CONCLUSION These results suggest that HHTE dose-dependently depolarizes ICC pacemaker potentials through 5-HT_3 and 5-HT_4 receptors via external and internal Ca2+ regulation and via G protein-, PKC-and Rho kinase-independent pathways. 展开更多
关键词 Hwangryunhaedok-tang Interstitial cells of Cajal Pacemaker potentials Gastrointestinal tract Motility
暂未订购 下载PDF
Use of Rats Mesenchymal Stem Cells Modified with mHCN2 Gene to Create Biologic Pacemakers 认领 引用 被引量:3
10
作者 马金 张存泰 +2 位作者 黄深 王国强 全小庆 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 2010年第4期447-452,共6页
The possibility of rats mesenchymal stem cells (MSCs) modified with murine hyperpolarization-activated cyclic nucleotide-gated 2 (mHCN2) gene as biological pacemakers in vitro was studied. The cultured MSCs were trans... The possibility of rats mesenchymal stem cells (MSCs) modified with murine hyperpolarization-activated cyclic nucleotide-gated 2 (mHCN2) gene as biological pacemakers in vitro was studied. The cultured MSCs were transfected with pIRES2-EGFP plasmid carrying enhanced green fluorescent protein (EGFP) gene and mHCN2 gene. The identification using restriction enzyme and sequencing indicated that the mHCN2 gene was inserted to the pIRES2-EGFP. Green fluorescence could be seen in MSCs after transfection for 24–48 h. The expression of mHCN2 mRNA and protein in the transfected cells was detected by RT-PCR and Western blot, and the quantity of mHCN2 mRNA and protein expression in transfected MSCs was 5.31 times and 7.55 times higher than that of the non-transfected MSCs respectively (P<0.05, P<0.05). IHCN2 was recorded by whole-cell patch clamp method. The effect of Cs+, a specific blocker of pacemaker current, was measured after perfusion by patch clamp. The results of inward current indicated that there was no inward current recording in non-transfected MSCs and a large voltage-dependent inward and Cs+-sensitive current activated on hyperpolarizations presented in the transfected MSCs. IHCN2 was fully activated around–140 mV with an activation threshold of –60 mV. The midpoint (V50) was –95.1±0.9 mV (n=9). The study demonstrates that mHCN2 mRNA and protein can be expressed and the currents of HCN2 channels can be detected in genetically modified MSCs. The gene-modified MSCs present a novel method for pacemaker genes into the heart or other electrical syncytia. 展开更多
关键词 stem cells gene therapy hyperpolarization-activated cyclic nucleotide-gated pacemaker current
暂未订购 下载PDF
Bow-and-arrow sign on point-of-care ultrasound for diagnosis of pacemaker lead-induced heart perforation:A case report and literature review 认领 引用
11
作者 Ni Chen Guang-Xian Miao +6 位作者 Liang-Qin Peng Yun-Hang Li Juan Gu Ying He Tao Chen Xiao-Yun Fu Zhou-Xiong Xing 《World Journal of Clinical Cases》 SCIE 2023年第7期1615-1625,共11页
BACKGROUND Pacemaker lead-induced heart perforation is a rare but life-threatening complication of pacemaker implantation,and timely diagnosis remains a challenge for clinicians.Here,we report a case of pacemaker lead... BACKGROUND Pacemaker lead-induced heart perforation is a rare but life-threatening complication of pacemaker implantation,and timely diagnosis remains a challenge for clinicians.Here,we report a case of pacemaker lead-induced cardiac perforation rapidly diagnosed by a“bow-and-arrow”sign on point-of-care ultrasound(POCUS).CASE SUMMARY A 74-year-old Chinese woman who had undergone permanent pacemaker implantation 26 d before suddenly developed severe dyspnea,chest pain,and hypotension.The patient had received emergency laparotomy for an incarcerated groin hernia and was transferred to the intensive care unit 6 d before.Computed tomography was not available due to unstable hemodynamic status,so POCUS was performed at the bedside and revealed severe pericardial effusion and cardiac tamponade.Subsequent pericardiocentesis yielded a large volume of bloody pericardial fluid.Further POCUS by an ultrasonographist revealed a unique“bow-and-arrow”sign indicating right ventricular(RV)apex perforation by the pacemaker lead,which facilitated the rapid diagnosis of lead perforation.Given the persistent drainage of pericardial bleeding,urgent off-pump open chest surgery was performed to repair the perforation.However,the patient died of shock and multiple organ dysfunction syndrome within 24 h post-surgery.In addition,we also performed a literature review on the sonographic features of RV apex perforation by lead.CONCLUSION POCUS enables the early diagnosis of pacemaker lead perforation at the bedside.A step-wise ultrasonographic approach and the“bow-and-arrow”sign on POCUS are helpful for rapid diagnosis of lead perforation. 展开更多
关键词 Point-of-care ultrasound Heart perforation Pacemaker lead Cardiac pacemaker Review Case report
暂未订购 下载PDF
Interference between pacemakers/implantable cardioverter defibrillators and video capsule endoscopy 认领 引用 被引量:1
12
作者 Dirk Bandorski Johannes Gehron Reinhard Hltgen 《World Journal of Gastrointestinal Endoscopy》 2013年第4期201-202,共2页
Our Letter to the Editor, related to the article "Small bowel capsule endoscopy in patients with cardiac pacemakers and implantable cardioverter defibrillators: Outcome analysis using telemetry" by Cuschieri... Our Letter to the Editor, related to the article "Small bowel capsule endoscopy in patients with cardiac pacemakers and implantable cardioverter defibrillators: Outcome analysis using telemetry" by Cuschieri et al , comments on some small errors, that slipped into the authors discussions. The given informations concerning the pacemakerand implantable cardioverter defibrillators modes were inaccurate and differ between the text and the table. Moreover, as 8 of 20 patient's pacemakers were programmed to VOO or DOO ("interference mode") and one patient was not monitored by telemetry during capsule endoscopy, 9 of 20 patients (45%) lack the informations of possible interference between capsule endoscopy their implanted device. Another objection refers to the interpretation of an electrocardiogram (figure 1, trace B) presented: in contrast to the author's opinion the marked spike should be interpreted as an artefact and not as "undersensing of a fibrillatory wave". Finally, three comments to cited reviews were not complete respectively not quoted correctly. 展开更多
关键词 Capsule endoscopy Small bowel capsule endoscopy Interference Cardiac pacemaker Implantable cardioverter defibrillator Telemetry
暂未订购 下载PDF
Contralateral pneumothorax in the subacute phase after pacemaker implantation:lead retention and follow-up 认领 引用
13
作者 Xiao-Dong CHEN Xu XU +2 位作者 Jia-Wen JI Hai-Lei LIU Jian-Ping SHEN 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2018年第12期744-746,共3页
An 89-year-old woman[body mass index(BMI)=20.27 kg/m^2)]with hypertension underwent implantation of a dual-chamber pacemaker because of dizziness and syncope due to sick sinus syndrome.Pacemaker implantation via the l... An 89-year-old woman[body mass index(BMI)=20.27 kg/m^2)]with hypertension underwent implantation of a dual-chamber pacemaker because of dizziness and syncope due to sick sinus syndrome.Pacemaker implantation via the left subclavian approach was performed on June 3,2017.A right ventricular active lead(TendrilTM STS 2088TC,St Jude Medical,Penang,Malaysia)and an atrial active lead(OptisenseTM 1999,St Jude Medical,Penang,Malaysia)were placed in the right ventricular apex and anterior wall of the right atrium,respectively. 展开更多
关键词 Atrial lead perforation Contralateral pneumothorax Pacemaker implantation
暂未订购 下载PDF
Pacemaker mimicking a tunnel digger 认领 引用
14
作者 Matthaios V.Didagelos Dimitrios Afendoulis +1 位作者 Petros Voutas Athanasios N.Kartalis 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2020年第8期528-529,共2页
An 81-year-old woman was admitted to our cardiology clinic with episodes of atypical chest pain.She had a personal history of hypertension and had undergone implantation of a VVIR pacemaker(in a subcutaneous pocket at... An 81-year-old woman was admitted to our cardiology clinic with episodes of atypical chest pain.She had a personal history of hypertension and had undergone implantation of a VVIR pacemaker(in a subcutaneous pocket at the right upper side of her thorax)fifteen years before at another institution,because of atrioventricular conduction disturbances(Figure 1DI). 展开更多
关键词 Arrhythmias Complications Erosion Infection Pacemaker
暂未订购 下载PDF
Wireless Power Supply Based on MNG-MNZ Metamaterial for Cardiac Pacemakers 认领 引用
15
作者 Weihua Chen Jingtao Jia +2 位作者 Xiaoheng Yan Yuhang Song Jiayi Li 《CES Transactions on Electrical Machines and Systems》 EI CSCD 2024年第1期103-112,共10页
To solve the low power transfer efficiency and magnetic field leakage problems of cardiac pacemaker wireless powering,we proposed a wireless power supply system suitable for implanted cardiac pacemaker based on mu-neg... To solve the low power transfer efficiency and magnetic field leakage problems of cardiac pacemaker wireless powering,we proposed a wireless power supply system suitable for implanted cardiac pacemaker based on mu-negative(MNG)and mu-nearzero(MNZ)metamaterials.First,a hybrid metamaterial consisted of central MNG unit for magnetic field concentration and surrounding MNZ units for magnetic leakage shielding was established by theoretical calculation.Afterwards,the magnetic field distribution of wireless power supply system with MNG-MNZ metamaterial slab was acquired via finite element simulation and verified to be better than the distribution with conventional MNG slab deployed.Finally,an experimental platform of wireless power supply system was established with which power transfer experiment and system temperature rise experiment were conducted.Simulation and experimental results showed that the power transfer efficiency was improved from 44.44%,19.42%,8.63%and 6.19%to 55.77%,62.39%,20.81%and 14.52%at 9.6 mm,20 mm,30 mm and 50 mm,respectively.The maximum SAR acquired by SAR simulation under human body environment was-7.14 dbm and maximum reduction of the magnetic field strength around the receiving coil was 2.82 A/m.The maximum temperature rise during 30min charging test was 3.85℃,and the safety requirements of human bodies were met. 展开更多
关键词 Cardiac pacemaker MNG metamaterial MNZ metamaterial Wireless power supply system
暂未订购 下载PDF
In vivo cardiac pacemaker function of differentiated human mesenchymal stem cells from adipose tissue transplanted into porcine hearts 认领 引用
16
作者 Fabrice F Darche Rasmus Rivinius +8 位作者 Ann-Kathrin Rahm Eva Köllensperger Uwe Leimer Günter Germann Miriam Reiss Michael Koenen Hugo A Katus Dierk Thomas Patrick A Schweizer 《World Journal of Stem Cells》 SCIE 2020年第10期1133-1151,共19页
BACKGROUND Mesenchymal stem cells(MSC)modified by gene transfer to express cardiac pacemaker channels such as HCN2 or HCN4 were shown to elicit pacemaker function after intracardiac transplantation in experimental ani... BACKGROUND Mesenchymal stem cells(MSC)modified by gene transfer to express cardiac pacemaker channels such as HCN2 or HCN4 were shown to elicit pacemaker function after intracardiac transplantation in experimental animal models.Human MSC derived from adipose tissue(haMSC)differentiate into cells with pacemaker properties in vitro,but little is known about their behavior after intracardiac transplantation.AIM To investigate whether haMSC elicit biological pacemaker function in vivo after transplantation into pig hearts.METHODS haMSC under native conditions(nhaMSC)or after pre-conditioning by medium differentiation(dhaMSC)(n=6 pigs each,5×106 cells/animal)were injected into the porcine left ventricular free wall.Animals receiving PBS injection served as controls(n=6).Four weeks later,total atrioventricular(AV)-block was induced by radiofrequency catheter ablation,and electronic pacemaker devices were implanted for backup stimulation and heart rate monitoring.Ventricular rate and rhythm of pigs were evaluated during a follow-up of 15 d post ablation by 12-lead-ECG with heart rate assessment,24-h continuous rate monitoring recorded by electronic pacemaker,assessment of escape recovery time,and pharmacological challenge to address catecholaminergic rate response.Finally,hearts were analyzed by histological and immunohistochemical investigations.RESULTS In vivo transplantation of dhaMSC into the left ventricular free wall of pigs elicited spontaneous and regular rhythms that were pace-mapped to ventricular injection sites(mean heart rate 72.2±3.6 bpm;n=6)after experimental total AV block.Ventricular rhythms were stably detected over a 15-d period and were sensitive to catecholaminergic stimulation(mean maximum heart rate 131.0±6.2 bpm;n=6;P<0.001).Pigs,which received nhaMSC or PBS presented significantly lower ventricular rates(mean heart rates 47.2±2.5 bpm and 37.4±3.2 bpm,respectively;n=6 each;P<0.001)and exhibited little sensitivity towards catecholaminergic stimulation(mean maximum heart rates 76.4±3.1 bpm and 60.5±3.1 bpm,respectively;n=6 each;P<0.05).Histological and immunohistochemical evaluation of hearts treated with dhaMSC revealed local clusters of transplanted cells at the injection sites that lacked macrophage or lymphocyte infiltrations or tumor formation.Intense fluorescence signals at these sites indicated membrane expression of HCN4 and other pacemaker-specific proteins involved in cardiac automaticity and impulse propagation.CONCLUSION dhaMSC transplanted into pig left ventricles sustainably induced rate-responsive ventricular pacemaker activity after in vivo engraftment for four weeks.The data suggest that pre-conditioned MSC may further differentiate along a pacemakerrelated lineage after myocardial integration and may establish superior pacemaker properties in vivo. 展开更多
关键词 Biological cardiac pacemaker Mesenchymal stem cells Differentiation Animal model Cell transplantation Stem cell therapy
暂未订购 下载PDF
Perioperative coagulation activation after permanent pacemaker placement 认领 引用
17
作者 Roman Kalinin Igor Suchkov +2 位作者 Vladislav Povarov Nina Mzhavanadze Olga Zhurina 《World Journal of Cardiology》 2023年第4期174-183,共10页
BACKGROUND Bradyarrhythmias are typically treated with permanent pacemakers(PM). The elimination of bradyarrhythmia by PM implantation improves the patient’s quality of life and prognosis, but it can also result in a... BACKGROUND Bradyarrhythmias are typically treated with permanent pacemakers(PM). The elimination of bradyarrhythmia by PM implantation improves the patient’s quality of life and prognosis, but it can also result in a number of sequalae. It is still unclear how PM implantation affects the hemostasis system’s parameters and how such parameters relate to different consequences after PM placement.AIM To assess the blood coagulation factor activity in PM patients throughout the perioperative period.METHODS Patients treated in the Department of Surgical Therapy of Cardiac Arrhythmias and Pacing at the Ryazan State "Regional Clinical Cardiology Dispensary" from April 2020 to December 2021 were included in the study. Before surgery, 7 and 30 d after PM placement, peripheral venous blood samples were withdrawn to measure the level of blood coagulation factor Ⅰ(FⅠ) and the activity of blood coagulation factors Ⅱ(FⅡ), Ⅴ(FⅤ), Ⅶ(FⅦ), Ⅷ(FⅧ), ⅸ(Fⅸ), ⅹ(Fⅹ), Ⅺ(FⅪ), Ⅻ(FⅫ). We used an automatic coagulometer Sysmex CA 660(Sysmex Europe, Germany) and reagents from Siemens(Siemens Healthcare Diagnostics Products GmbH, Germany).RESULTS The study included 146 patients. The activity of factors FⅤ [147.7(102.1-247.55)% vs 103.85(60-161.6)% vs 81.8(67.15-130.65)%, P = 0.002], FⅧ [80.4(60.15-106.25)% vs 70.3(48.5-89.1)% vs 63.7(41.6-88.25)%, P = 0.039], Fⅸ [86.2(70.75-102.95)% vs 75.4(59.2-88.3)% vs 73.9(56.45-93.05)%, P = 0.014], Fⅹ [188.9(99.3-308.18)% vs 158.9(83.3-230)% vs 127.2(95.25-209.35)%, P = 0.022], FⅪ [82.6(63.9-103.6)% vs 69.75(53.8-97.6)% vs 67.3(54.25-98.05)%, P = 0.002], FⅫ [87.6(67.15-102.3)% vs 78.9(63.4-97.05)% vs 81.2(62.15-97.4)%, P < 0.001] decreased at 7 and 30 d after surgery;FⅡ activity [157.9(109.7-245.25)% vs 130(86.8-192.5)% vs 144.8(103.31-185.6)%, P = 0.021] decreased at 7 d and increased at 30 d postoperatively. There were no statistically significant changes in the FVII activity within 30 d after PM placement [182.2(85.1-344.8)% vs 157.2(99.1-259)% vs 108.9(74.9-219.8)%, P = 0.128]. Subgroup analysis revealed similar changes only in patients on anticoagulant therapy. FⅫ activity decreased in patients on antiplatelet therapy [82(65.8-101.9)% vs 79.9(63.3-97.1)% vs 89.7(75.7-102.5)%, P = 0.01] 7 d after surgery, returning to baseline values at 30 d postoperatively.CONCLUSION PM placement and anticoagulant therapy were associated with decreased activity of clotting factors FⅤ, FⅧ, Fⅸ, Fⅹ, FⅪ, FⅫ in the postoperative period. FⅧ activity did not decrease within 30 d after PM placement, which may indicate endothelial injury caused by lead placement. 展开更多
关键词 Hemostasis Blood coagulation Cardiac pacemaker Anticoagulants Postoperative complications
暂未订购 下载PDF
Successful transcatheter arterial embolization treatment for chest wall haematoma following permanent pacemaker implantation: A case report 认领 引用
18
作者 Jing Zheng Xiao-Ming Tu Zhen-Yan Gao 《World Journal of Clinical Cases》 SCIE 2022年第32期11877-11881,共5页
BACKGROUND Haematoma is one of the main complications associated with pacemaker implantation.Pseudoaneurysm is a rare condition that is not easy to identify and is often overlooked.CASE SUMMARY A female patient diagno... BACKGROUND Haematoma is one of the main complications associated with pacemaker implantation.Pseudoaneurysm is a rare condition that is not easy to identify and is often overlooked.CASE SUMMARY A female patient diagnosed with high-grade atrioventricular block underwent permanent pacemaker implantation.During the operation,puncturing a small branch of the right subclavian artery developed into a pseudoaneurysm and resulted in further haematoma formation.Conventional treatment of compression haemostasis and haemostatic drugs was not effective.A series of timely transcatheter arterial embolizations avoided serious complications.CONCLUSION More possible conditions should be taken into consideration as haematoma is discovered,and timely treatment might prevent severe adverse events. 展开更多
关键词 Permanent pacemaker implantation Haematoma Pseudoaneurysm Transcatheter arterial embolization Case report
暂未订购 下载PDF
Pacemaker electrode rupture causes recurrent syncope:A case report 认领 引用
19
作者 Xiao-Yong Zhu Xin-Hu Tang Wen-Yin Huang 《World Journal of Clinical Cases》 SCIE 2022年第33期12352-12357,共6页
BACKGROUND Currently,the implantation of permanent cardiac pacemakers entails mostly subclavian vein puncture,which is relatively simpler and easier to master.However,due to individual differences,some patients carry ... BACKGROUND Currently,the implantation of permanent cardiac pacemakers entails mostly subclavian vein puncture,which is relatively simpler and easier to master.However,due to individual differences,some patients carry a narrow space between the clavicle and the first rib.If the range of activity of the upper limb is increased,the friction between the electrode wire and the bone gap leads to the breakage of the electrode wire,which is manifested by poor pacemaker perception and pacing.CASE SUMMARY A 68-year-old woman underwent permanent pacemaker implantation in our hospital because of third-degree atrioventricular block 6 years ago.At that time,the patient was recommended to have a dual-chamber permanent pacemaker implantation,and finally chose a single-chamber permanent pacemaker because she could not afford the cost.The patient has repeatedly lost consciousness for no obvious reason in the past 3 d,and went to our hospital for treatment.The chest X-ray showed that the pacemaker electrode was broken.After the patient was given a pacemaker electrode replacement,the patient did not continue to lose consciousness.CONCLUSION Because the electrodes implanted in the subclavian approach are close to the clavicle and the first rib,the pacemaker electrodes may wear out.If the patient loses consciousness again after the pacemaker is implanted,we should consider whether there is a pacemaker.The possibility of electrode breakage,and timely help the patient to replace the new pacemaker electrodes. 展开更多
关键词 Syncope Pacemaker Lead fracture Subclavian crush Case report
暂未订购 下载PDF
Risk of permanent pacemaker implantation following transcatheter aortic valve replacement:Which factors are most relevant? 认领 引用
20
作者 Akash Batta Juniali Hatwal 《World Journal of Cardiology》 2024年第2期49-53,共5页
Transcatheter aortic valve replacement(TAVR)has emerged as a formidable treatment option for severe symptomatic aortic stenosis ahead of surgical aortic valve replacement.The encouraging results from large randomized ... Transcatheter aortic valve replacement(TAVR)has emerged as a formidable treatment option for severe symptomatic aortic stenosis ahead of surgical aortic valve replacement.The encouraging results from large randomized controlled trials has resulted in an exponential rise in the use of TAVR even in the low-risk patients.However,this is not without challenges.Need for permanent pacemaker(PPM)post-TAVR remains the most frequent and clinically relevant challenge.Naturally,identifying risk factors which predispose an individual to develop high grade conduction block post-TAVR is important.Various demographic factors,electrocardiographic features,anatomic factors and procedural characteristics have all been linked to the development of advanced conduction block and need for PPM following TAVR.Amongst these electrophysiological variables,most notably a prolonged QRS>120 ms regardless of the type of conduction block seems to be one of the strongest predictors on logistic regression models.The index study by Nwaedozie et al highlights that patients requiring PPM post-TAVR had higher odds of having a baseline QRS>120 ms and were more likely to be having diabetes mellitus that those who did not require PPM. 展开更多
关键词 Transcatheter aortic valve replacement Permanent pacemaker Diabetes mellitus QRS duration Electrophysiological variables
暂未订购 下载PDF
上一页 1 2 9 下一页 到第
在线咨询 使用帮助 返回顶部 意见反馈