Constructing self-protected metastable intermolecular composites(MICs) enables the regulation of microstructures towards boosting controllable detonation performance,and also prevents information leakage,which is mean...Constructing self-protected metastable intermolecular composites(MICs) enables the regulation of microstructures towards boosting controllable detonation performance,and also prevents information leakage,which is meaningful but challenging.Herein,a convenient and efficient method of combining highly-controlled electrophoretic assembly,surface modification and microwave heat treatment was employed to design promising heattriggered wettability switchable high-energy smart C-doped Al/Cr2O3MIC,and surface modification mechanism was proposed,respectively.The anti-wetting ability of the product was demonstrated by a series of tests of water contact angle,impact resistance,immersion,selfcleaning,etc.The key information recording/encryption procedures were realized by constructing a hydrophilic/hydrophobic interface and adjusting the wettability of the product.In addition,the output heat of asobtained smart MIC can reach ~1.5 kJ·g-1,and its attenuation rate was only ~30% even after underwater aging,further verifying its potential practicality.Thus,our design provides a promising strategy for engineering smart MIC with diversified functional structures for blasting applications and beyond.展开更多
We present a conceptual configuration of a high-temperature superconducting(HTS)magnet made from REBCO(Re=Rare Earth,B=Barium,C=Copper,O=Oxide)annular plates,called a Bitter-like HTS magnet,which can operate in pe...We present a conceptual configuration of a high-temperature superconducting(HTS)magnet made from REBCO(Re=Rare Earth,B=Barium,C=Copper,O=Oxide)annular plates,called a Bitter-like HTS magnet,which can operate in persistent current mode without joint resistance and can be excited by a flux pump and without current leads and a persistent power supply.An REBCO annular magnet which can generate 1.5 T corresponding to the operating current density 80%of critical current density of the magnet at an operating temperature of65 K is conceptually designed.Then the thermal stability of the magnet is numerically simulated by Comsol software.Whein a piece of RBCO annular plate quenches,the maximum released energy is its stored energy because each REBCO annular plate in the Bitter-like magnet is in parallel.To calculate the stored energy in the REBCO annular plate,the inductance of every annular plate,including self-inductance and mutual inductance,is calculated.Compared with the minimum quench energy(MQE)and stored energy in one REBCO annular plate,the stored energy in one REBCO annular plate is always smaller than the MQE,and the REBCO annular plate will not be damaged even though the stored energy in the REBCO annular plate is fully released,which indicates that this 1.5 T Bitter-like magnet has the property of self-protection.展开更多
This paper mainly studies the optimal investment problem of defined contribution(DC)pension under the self-protection and minimum security.First,we apply Ito?theorem to obtain the differential equation of the real sto...This paper mainly studies the optimal investment problem of defined contribution(DC)pension under the self-protection and minimum security.First,we apply Ito?theorem to obtain the differential equation of the real stock price after discounting inflation.Then,under the constraint of external guarantee of DC pension terminal wealth,self-protection is introduced to study the maximization of the expected utility of terminal wealth at retirement time and any time before retirement.The explicit solution of the optimal investment strategy of DC pension at retirement time and any time before retirement should be derived by martingale method.Finally,the influence of selfprotection on the optimal investment strategy of DC pension is numerically analyzed.展开更多
Static secure techniques, such as firewall, hierarchy filtering, distributed disposing,layer management, autonomy agent, secure communication, were introduced in distributed intrusion detection. The self-protection ag...Static secure techniques, such as firewall, hierarchy filtering, distributed disposing,layer management, autonomy agent, secure communication, were introduced in distributed intrusion detection. The self-protection agents were designed, which have the distributed architecture,cooperate with the agents in intrusion detection in a loose-coupled manner, protect the security of intrusion detection system, and respond to the intrusion actively. A prototype self-protection agent was implemented by using the packet filter in operation system kernel. The results show that all the hosts with the part of network-based intrusion detection system and the whole intrusion detection system are invisible from the outside and network scanning, and cannot apperceive the existence of network-based intrusion detection system. The communication between every part is secure. In the low layer, the packet streams are controlled to avoid the buffer leaks exist ing in some system service process and back-door programs, so as to prevent users from misusing and vicious attack like Trojan Horse effectively.展开更多
Objective: to analyze the self-defense strategies of laboratory staff in AIDS testing. Methods: we used a random sample of 40 staff members from the CDC's laboratory and a homemade questionnaire on CDC's self-...Objective: to analyze the self-defense strategies of laboratory staff in AIDS testing. Methods: we used a random sample of 40 staff members from the CDC's laboratory and a homemade questionnaire on CDC's self-defense strategy for HIV testing to survey health care workers, analyze health care workers' self-defense behaviors and propose targeted and effective measures. Results: twenty-three of the 40 test workers were infected with HIV, bringing the total number to 85. The main ways of exposure were amputation wound exposure, acupuncture, intact skin exposure, skin injury exposure, and eye mucosa exposure, some on the hand and face. According to self-defense knowledge survey, the correct rate of AIDS pathogenesis, transmission route, occupational exposure concept and way is high, but the correct rate of post-exposure treatment, window period concept, significance and prevention is low. Conclusion: due to the lack of self-defense knowledge in AIDS testing, CDC has strengthened self-defense knowledge training for medical staff to avoid occupational exposure and reduce the risk of occupational exposure.展开更多
Objective: To understand the situation of nursing students was stabbed by sharp instrument,in order to provide a scientific basis to take protective measures.Method:By using a self-designed questionnaire.The 100 nur...Objective: To understand the situation of nursing students was stabbed by sharp instrument,in order to provide a scientific basis to take protective measures.Method:By using a self-designed questionnaire.The 100 nursing students were randomly selected from a hospital for retrospective investigation.There are 98 valid data.Results: The data shows that sharp instrument injury is more common in nursing students. Nursing students' protection consciousness is low, and protective ability is poor.Conclusion: Nursing students awareness of self- protection to sharp instrument injury is not enough,in order to avoid the risk of infection of nursing students occupation.When they entered the clinics, practice of systematic pre occupation safety education is very necessary;and the school and the hospital should actively implement the management standardized operation regulations;and put up student occupation injury management regulations;to improve the safety performance of nursing equipment.展开更多
In the era of artificial intelligence,the efficient perception and processing of massive volumes of visual information place high demands on machine vision systems.Inspired by the remarkable adaptive capabilities of h...In the era of artificial intelligence,the efficient perception and processing of massive volumes of visual information place high demands on machine vision systems.Inspired by the remarkable adaptive capabilities of human vision in dynamic environments,various optoelectronic materials and biomimetic intelligent vision devices have emerged.However,most existing bio-inspired vision devices rely on external gate voltages or complex circuits to achieve dynamic modulation of visual sensitivity.It is attractive but challenging to realize all-optically controlled adaptive visual perception within an individual device.Based on the switching between positive and negative photoconductivity effects,this work presents a biomimetic sensor for all-optically controlled artificial visual adaptation and self-protection within a one-dimensional ZnO/MAPbBr3 heterojunction.Through ultraviolet light modulation of oxygen vacancy states,the competition between intrinsic photoconduction and trapmediated carrier capture is regulated,enabling dynamic control of the visible-light photoconductive behavior within an individual device.The flexibly tunable photoresponse successfully mimics the scotopic adaptation process involving photopigment regeneration under weak illumination,the photopic adaptation process involving photopigment bleaching in bright environments,and an eyelid-like self-protection behavior in response to intense light exposure.This work demonstrates the integration of multi-level adaptive and protective visual functions within an individual device,offering a promising strategy for the development of next-generation intelligent biomimetic sensors for machine vision system.展开更多
Erythrocyte membrane(EM)-camouflaged chemotherapeutic delivery nanovehicles hold promise for solid tumor therapy because of their excellent biostability and biocompatibility. However, it is accompanied with insufficie...Erythrocyte membrane(EM)-camouflaged chemotherapeutic delivery nanovehicles hold promise for solid tumor therapy because of their excellent biostability and biocompatibility. However, it is accompanied with insufficient targeting effect and deficient pharmacokinetic behavior due to the lack of a regulated biointerface to navigate and overcome biological transportation obstacles in solid tumor therapy.Herein, an anti-epidermal growth factor receptor(EGFR) aptamer(EApt) modified and EM-cloaked chemotherapeutic nanomissile delivery system was constructed. The anchored-EApt acting as a specific EGFR suppressor promotes to inhibit the overexpression of EGFR and initiate the cell apoptosis. Importantly, the resulting PLGA-DOX@EM-EApt orchestrated the bioactivity of each component and provided synergistic cell apoptosis and antitumor effects by precisely suppressing EGFR expression levels and delivering DOX. The in vitro and in vivo experimental results confirmed that the immune escape and active targeting behaviors of PLGA-DOX@EM-EApt could significantly promote its drug retention and tumor inhibition abilities. Our findings propose a novel strategy using the biointerface functionalization technique, demonstrating a promising therapeutic platform via a biomimetic drug delivery system for precise solid tumor recognition and synergistic therapy.展开更多
Objectives:Rural areas are the weakest place for epidemic prevention and control,yet few studies have specifically conducted surveys in rural areas.The purpose of this study is to assess rural residents’knowledge of ...Objectives:Rural areas are the weakest place for epidemic prevention and control,yet few studies have specifically conducted surveys in rural areas.The purpose of this study is to assess rural residents’knowledge of the COVID-19 and its prevention in China.Methods:A cross-sectional survey study containing 1,426 samples was conducted in Fuqing,China to assess rural residents’knowledge of the COVID-19 and its prevention.Logistic regression was used to identify potential differences in participants’knowledge of COVID-19 and its prevention and control in different population subgroups.Results:The mean and median of residents’knowledge of COVID-19 was 5.53 and 6 points,respectively.The mean and median of residents’knowledge related to self-protection against COVID-19 was 10.34 and 11 points,respectively.Older adults(AOR45e59=2.26,95%CI 1.20 to 4.27;AOR60-69=3.13,95%CI 1.63 to 5.98;AOR70=4.68,95%CI 2.35 to 9.33)were more deficient in knowledge of COVID-19.Those who were better educated and with a higher average annual household income were less likely to be deficient in the knowledge of COVID-19 and knowledge of self-protection against COVID-19.Moreover,those who were single,divorced,or widowed(AOR=1.67,95%CI 1.13 to 2.46)were more deficient in the knowledge of self-protection against COVID-19.Conclusions:Our study suggests that when facing a pandemic like COVID-19,the key is to inform the public to understand simple and effective self-protection measures.Therefore,we call on the govern-ments to give priority to publicity and education on self-prevention measures for the targeted pop-ulations and regions.This is most evident among the vulnerable groups like those who were unmarried,elderly,and those with low education or low income.Similar suggestions may be of use in other countries as well.展开更多
The impact of risk correlation on firm's investments in information system security is studied by using quantification models combining the ideas of the risk management theory and the game theory. The equilibrium lev...The impact of risk correlation on firm's investments in information system security is studied by using quantification models combining the ideas of the risk management theory and the game theory. The equilibrium levels of self-protection and insurance coverage under the non- cooperative condition are compared with socially optimal solutions, and the associated coordination mechanisms are proposed. The results show that self-protection investment increases in response to an increase in potential loss when the interdependent risk is small; the interdependent risk of security investments often induce firms to underinvest in security relative to the socially efficient level by ignoring marginal external costs or benefits conferred on others. A subsidy on self-protection investment from the government can help coordinate a firm's risk management decision and, thereby, improve individual security level and overall social welfare.展开更多
Objective: to explore the application effect of Orem self-care model in elderly diabetes care. Methods: from November 2019 to October 2021, 70 elderly patients with diabetes in our hospital were randomly divided into ...Objective: to explore the application effect of Orem self-care model in elderly diabetes care. Methods: from November 2019 to October 2021, 70 elderly patients with diabetes in our hospital were randomly divided into 35 patients in each group. The control group received routine nursing, and the observation group received Orem self-nursing mode intervention on the basis of routine nursing. Results: the blood glucose level of the observation group was lower than that of the control group (P<0.05). The self-protection ability and self-management level of observation group were higher than control group (P<0.05). The quality of life in the observation group was higher than that in the control group (P<0.05). The incidence of diabetes-related complications in observation group was lower than that in control group (P<0.05). Conclusion: the application of Orem self-care model in the nursing of elderly diabetes patients can improve patients' self-care ability, self-management ability and living standard, and reduce the incidence of related complications.展开更多
In order to solve the problem that the traditional space jamming countermeasure cannot deal with the mainlobe self-protecting jammings,a polarization-space joint mainlobe jamming countermeasure technique based on divi...In order to solve the problem that the traditional space jamming countermeasure cannot deal with the mainlobe self-protecting jammings,a polarization-space joint mainlobe jamming countermeasure technique based on divided dimensions is proposed.Specifically,the digital beam of each row and column is firstly formed by using dual polarization digital receiving in multi-channel.Then,the polarization-space joint cancellation in both azimuth and elevation dimensions is carried out based on the polarization-space joint difference between the target echo and the jamming,as well as the divided dimension feature of the row and column beams.Finally,the sum and difference beams of the full array in the elevation or azimuth dimension are formed by the beams after jamming cancelling,and the monopulse angle measurement is further employed to obtain target angles.The effectiveness of the proposed technique is verified by simulations,indicating that the self-protecting jamming and multiple mainlobe following jammings can be both cancelled simultaneously with the angle measurement unchanged.展开更多
Many developing countries need ecologically clean power sources (PS). The nuclear power plants are such sources. However, a great number of the developing countries do not possess developed large capacity power system...Many developing countries need ecologically clean power sources (PS). The nuclear power plants are such sources. However, a great number of the developing countries do not possess developed large capacity power systems. Moreover, currently in the developing countries, there are no highly skilled personnel to provide construction and reliable and safe operation of the nuclear plants, which are complex and potentially hazardous systems. In some countries, the level of terroristic threat is extremely high. For that reason, there are specific requirements to the nuclear PSs intended for use in the developing countries. In the presented report, the specific requirements which must be met by the NPT proposed for use in developing countries are formulated, basic statements of the SVBR-100 concept are presented, design and principal scheme of the reactor fa-ility are described, major characteristics of SVBR-100 are summarized.展开更多
Fast reactors used lead-bismuth eutectic (LBE) and lead as coolants possess very high level of inherent self-protection and passive safety against severe accident. So, population radiophobia can be overcome. That type...Fast reactors used lead-bismuth eutectic (LBE) and lead as coolants possess very high level of inherent self-protection and passive safety against severe accident. So, population radiophobia can be overcome. That type of reactors can be simultaneously more safely and more cheaply. As all other coolants, LBE and lead coolant (LC) possess the certain virtues and shortcomings. The presented report includes the comparative analysis of characteristic properties of those coolants, their impact on reactor safety, reliability and operating characteristics. The conclusion is made about promising usage of FRs with these coolants in future NP after the experience in operating of the prototypes of such reactors has been obtained.展开更多
The article reviews the stable logic analysis model of complex systems or steady multilateral systems with two non-compatibility relations. Energy concept in Physics is introduced to the multilateral systems and used ...The article reviews the stable logic analysis model of complex systems or steady multilateral systems with two non-compatibility relations. Energy concept in Physics is introduced to the multilateral systems and used to deal with the multilateral system diseases. By using mathematical reasoning, it is demonstrated that the treatment principle: “Virtual disease is to fill his mother but real disease is to rush down his son” and “Strong inhibition of the same time, support the weak” which due to the “Yin Yang Wu Xing” Theory in Traditional Chinese Medicine (TCM).展开更多
By using mathematical reasoning, this paper demonstrates the mathematical intervening principle: “Virtual disease is to fill his mother but real disease is to rush down his son” (虚则补其母, 实则泄其子) and “Strong...By using mathematical reasoning, this paper demonstrates the mathematical intervening principle: “Virtual disease is to fill his mother but real disease is to rush down his son” (虚则补其母, 实则泄其子) and “Strong inhibition of the same time, support the weak” (抑强扶弱) based on “Yin Yang Wu Xing” Theory in image mathematics of Traditional Chinese Mathematics (TCMath). We defined generalized relations and generalized reasoning, introduced the concept of steady multilateral systems with two non-compatibility relations, and discussed its energy properties. Later based on the intervention principle in image mathematics of TCMath and treated the research object of the image mathematics as a steady multilateral system, it has been proved that the mathematical intervening principle is true. The kernel of this paper is the existence and reasoning of the non-compatibility relations in steady multilateral systems, and it accords with the oriental thinking model.展开更多
The conflict between safety and economics requirements is peculiar to the present nuclear power (NP). The main point of the conflict is that for traditional type reactors the increase of requirements to safety of nucl...The conflict between safety and economics requirements is peculiar to the present nuclear power (NP). The main point of the conflict is that for traditional type reactors the increase of requirements to safety of nuclear power plants (NPP) worsens their economical characteristics. This is caused by large potential energy accumulated in reactor coolant. In the presented paper the opportunity and expediency of changeover to reactors with heavy liquid-metal coolants (HLMC) in future NP is grounded. First of all, this refers to lead-bismuth coolant (LBC) mastered in the process of operating nuclear submarines (NS) reactors. The reactor facilities (RFs) of that type cannot cause destruction of defense barriers and make possible deterministic elimination of severe accidents with catastrophic radioactivity release. So it will make possible to eliminate the highlighted conflict and reasons for existence of population’s radiophobia. Lead-bismuth fast reactor SVBR-100 with electric power of 100 MWe is the reactor facility of that type. The effect of accumulated in coolant potential energy on safety and economics is considered. Main specific features of SVBR-100 technology providing a high level of inherent self-protection and passive safety are presented.展开更多
The degree and characteristics of physical degradation of macro-DNA molecules by common laboratory manipulations are reported. With linearized lambda-phage viral DNA as the model DNA, fragmentation of macro-DNA by var...The degree and characteristics of physical degradation of macro-DNA molecules by common laboratory manipulations are reported. With linearized lambda-phage viral DNA as the model DNA, fragmentation of macro-DNA by various indispensable laboratory manipulations were investigated using a high sensitivity flow cytometric setup. Investigated manipulations included pipetting, vortexing, rocking, freeze-thawing, ultrasonication and ultrafiltration. “Exhaustive counting” of the intact lambda DNA molecules following such manipulations enabled a quantitative assessment of the resulting fragmentation, which also revealed the type of degradation reflected in the fragmentation patterns. The use of high sensitivity flow cytometry was especially suited to investigate the degradation of dilute DNA solutions that may not be suitable for analysis using traditional methods. Notable findings of this study included: the boarderline-size of DNA chains in terms of susceptibility to shear stresses by such manipulations;discernable instability of nicked DNAs;shattering-fragmentation of DNAs by freeze-thawing or ultrasonication;effectiveness of some protection media;marked “self-protection effect” of concentrated DNA solutions. These findings support and refine our traditional knowledge on how to maintain the physical integrity of macro-DNA molecules against inevitable laboratory manipulations.展开更多
Objective: to explore the application effect of continuous nursing system in the nursing of discharged patients in intravenous infusion port. Methods: from February 2019 to January 2021, 82 patients with implantable i...Objective: to explore the application effect of continuous nursing system in the nursing of discharged patients in intravenous infusion port. Methods: from February 2019 to January 2021, 82 patients with implantable intravenous infusion port were treated in our hospital. According to the parity of admission number, 41 odd cases entered the control group for routine discharge follow-up nursing;An even number of 41 patients entered the experimental group and adopted the continuous nursing system. The maintenance compliance, self-care ability and quality of life of infusion port were compared. Results: the excellent and good rate of maintenance compliance of infusion port in the experimental group was higher than that in the control group (97.56% vs 82.93%);After the intervention, the scores of ESCA and QOL in the experimental group were significantly higher than those in the control group. The test results showed that there was significant difference (P < 0.05). Conclusion: the continuous nursing system for discharged patients in intravenous infusion port can not only improve the maintenance compliance of infusion port, but also improve their self-care ability and quality of life, so it is worth popularizing.展开更多
Objective: to explore the effect of all-round nursing on psychological state and self-care ability of patients with myocardial infarction. Methods: 90 patients with myocardial infarction who were hospitalized in Taizh...Objective: to explore the effect of all-round nursing on psychological state and self-care ability of patients with myocardial infarction. Methods: 90 patients with myocardial infarction who were hospitalized in Taizhou People's Hospital from January 2018 to December 2020 were selected and randomly selected according to numbers. The patients were divided into two groups. Conventional care was given to the control group, while all-round care was given to the observation group. The change of mentality and self-care ability of the patients in the two groups were compared. Results: through nursing, compared with the control group, the SAS and SDS scores of the observation group were significantly improved, and the scores of self-care ability were all increased (P < 0.05). Conclusion: all-round nursing for patients with myocardial infarction can play a significant role in maintaining more stable psychological mood and improving self-care ability of patients, which is worthy of promotion and use.展开更多
基金financially supported by the National Natural Science Foundation of China (Nos.21805014,82102635,52373087,52003300 and 22109120)Chongqing Municipal Education Commission (Nos.CXQT20026 and KJQN202201408)。
摘要Constructing self-protected metastable intermolecular composites(MICs) enables the regulation of microstructures towards boosting controllable detonation performance,and also prevents information leakage,which is meaningful but challenging.Herein,a convenient and efficient method of combining highly-controlled electrophoretic assembly,surface modification and microwave heat treatment was employed to design promising heattriggered wettability switchable high-energy smart C-doped Al/Cr2O3MIC,and surface modification mechanism was proposed,respectively.The anti-wetting ability of the product was demonstrated by a series of tests of water contact angle,impact resistance,immersion,selfcleaning,etc.The key information recording/encryption procedures were realized by constructing a hydrophilic/hydrophobic interface and adjusting the wettability of the product.In addition,the output heat of asobtained smart MIC can reach ~1.5 kJ·g-1,and its attenuation rate was only ~30% even after underwater aging,further verifying its potential practicality.Thus,our design provides a promising strategy for engineering smart MIC with diversified functional structures for blasting applications and beyond.
基金Supported by the Fundamental Research Funds for the Central Universities under Grant No 2018MS004
摘要We present a conceptual configuration of a high-temperature superconducting(HTS)magnet made from REBCO(Re=Rare Earth,B=Barium,C=Copper,O=Oxide)annular plates,called a Bitter-like HTS magnet,which can operate in persistent current mode without joint resistance and can be excited by a flux pump and without current leads and a persistent power supply.An REBCO annular magnet which can generate 1.5 T corresponding to the operating current density 80%of critical current density of the magnet at an operating temperature of65 K is conceptually designed.Then the thermal stability of the magnet is numerically simulated by Comsol software.Whein a piece of RBCO annular plate quenches,the maximum released energy is its stored energy because each REBCO annular plate in the Bitter-like magnet is in parallel.To calculate the stored energy in the REBCO annular plate,the inductance of every annular plate,including self-inductance and mutual inductance,is calculated.Compared with the minimum quench energy(MQE)and stored energy in one REBCO annular plate,the stored energy in one REBCO annular plate is always smaller than the MQE,and the REBCO annular plate will not be damaged even though the stored energy in the REBCO annular plate is fully released,which indicates that this 1.5 T Bitter-like magnet has the property of self-protection.
基金Supported by the National Social Science Foundation of China(20BTJ048)Anhui University Humanities and Social Science Research Major Project(SK2021ZD0043)。
摘要This paper mainly studies the optimal investment problem of defined contribution(DC)pension under the self-protection and minimum security.First,we apply Ito?theorem to obtain the differential equation of the real stock price after discounting inflation.Then,under the constraint of external guarantee of DC pension terminal wealth,self-protection is introduced to study the maximization of the expected utility of terminal wealth at retirement time and any time before retirement.The explicit solution of the optimal investment strategy of DC pension at retirement time and any time before retirement should be derived by martingale method.Finally,the influence of selfprotection on the optimal investment strategy of DC pension is numerically analyzed.
摘要Static secure techniques, such as firewall, hierarchy filtering, distributed disposing,layer management, autonomy agent, secure communication, were introduced in distributed intrusion detection. The self-protection agents were designed, which have the distributed architecture,cooperate with the agents in intrusion detection in a loose-coupled manner, protect the security of intrusion detection system, and respond to the intrusion actively. A prototype self-protection agent was implemented by using the packet filter in operation system kernel. The results show that all the hosts with the part of network-based intrusion detection system and the whole intrusion detection system are invisible from the outside and network scanning, and cannot apperceive the existence of network-based intrusion detection system. The communication between every part is secure. In the low layer, the packet streams are controlled to avoid the buffer leaks exist ing in some system service process and back-door programs, so as to prevent users from misusing and vicious attack like Trojan Horse effectively.
摘要Objective: to analyze the self-defense strategies of laboratory staff in AIDS testing. Methods: we used a random sample of 40 staff members from the CDC's laboratory and a homemade questionnaire on CDC's self-defense strategy for HIV testing to survey health care workers, analyze health care workers' self-defense behaviors and propose targeted and effective measures. Results: twenty-three of the 40 test workers were infected with HIV, bringing the total number to 85. The main ways of exposure were amputation wound exposure, acupuncture, intact skin exposure, skin injury exposure, and eye mucosa exposure, some on the hand and face. According to self-defense knowledge survey, the correct rate of AIDS pathogenesis, transmission route, occupational exposure concept and way is high, but the correct rate of post-exposure treatment, window period concept, significance and prevention is low. Conclusion: due to the lack of self-defense knowledge in AIDS testing, CDC has strengthened self-defense knowledge training for medical staff to avoid occupational exposure and reduce the risk of occupational exposure.
摘要Objective: To understand the situation of nursing students was stabbed by sharp instrument,in order to provide a scientific basis to take protective measures.Method:By using a self-designed questionnaire.The 100 nursing students were randomly selected from a hospital for retrospective investigation.There are 98 valid data.Results: The data shows that sharp instrument injury is more common in nursing students. Nursing students' protection consciousness is low, and protective ability is poor.Conclusion: Nursing students awareness of self- protection to sharp instrument injury is not enough,in order to avoid the risk of infection of nursing students occupation.When they entered the clinics, practice of systematic pre occupation safety education is very necessary;and the school and the hospital should actively implement the management standardized operation regulations;and put up student occupation injury management regulations;to improve the safety performance of nursing equipment.
基金supported by the National Natural Science Foundation of China(62375049,62404040,and 62335003)the Excellent Postdoctoral Program of Jiangsu Province(2023ZB077)。
摘要In the era of artificial intelligence,the efficient perception and processing of massive volumes of visual information place high demands on machine vision systems.Inspired by the remarkable adaptive capabilities of human vision in dynamic environments,various optoelectronic materials and biomimetic intelligent vision devices have emerged.However,most existing bio-inspired vision devices rely on external gate voltages or complex circuits to achieve dynamic modulation of visual sensitivity.It is attractive but challenging to realize all-optically controlled adaptive visual perception within an individual device.Based on the switching between positive and negative photoconductivity effects,this work presents a biomimetic sensor for all-optically controlled artificial visual adaptation and self-protection within a one-dimensional ZnO/MAPbBr3 heterojunction.Through ultraviolet light modulation of oxygen vacancy states,the competition between intrinsic photoconduction and trapmediated carrier capture is regulated,enabling dynamic control of the visible-light photoconductive behavior within an individual device.The flexibly tunable photoresponse successfully mimics the scotopic adaptation process involving photopigment regeneration under weak illumination,the photopic adaptation process involving photopigment bleaching in bright environments,and an eyelid-like self-protection behavior in response to intense light exposure.This work demonstrates the integration of multi-level adaptive and protective visual functions within an individual device,offering a promising strategy for the development of next-generation intelligent biomimetic sensors for machine vision system.
基金supported by the National Natural Science Foundation of China (Nos. 82073807 and 81973277)the WorldClass Universities (Disciplines)the Characteristic Development Guidance Funds for the Central Universities,China (No. PY3A012)。
摘要Erythrocyte membrane(EM)-camouflaged chemotherapeutic delivery nanovehicles hold promise for solid tumor therapy because of their excellent biostability and biocompatibility. However, it is accompanied with insufficient targeting effect and deficient pharmacokinetic behavior due to the lack of a regulated biointerface to navigate and overcome biological transportation obstacles in solid tumor therapy.Herein, an anti-epidermal growth factor receptor(EGFR) aptamer(EApt) modified and EM-cloaked chemotherapeutic nanomissile delivery system was constructed. The anchored-EApt acting as a specific EGFR suppressor promotes to inhibit the overexpression of EGFR and initiate the cell apoptosis. Importantly, the resulting PLGA-DOX@EM-EApt orchestrated the bioactivity of each component and provided synergistic cell apoptosis and antitumor effects by precisely suppressing EGFR expression levels and delivering DOX. The in vitro and in vivo experimental results confirmed that the immune escape and active targeting behaviors of PLGA-DOX@EM-EApt could significantly promote its drug retention and tumor inhibition abilities. Our findings propose a novel strategy using the biointerface functionalization technique, demonstrating a promising therapeutic platform via a biomimetic drug delivery system for precise solid tumor recognition and synergistic therapy.
基金supported by funding from Fujian Medical University(Grant No.XRCZX 2020020Grant No.XRZCX 2017035,Grant No.XRZCX 2020034).
摘要Objectives:Rural areas are the weakest place for epidemic prevention and control,yet few studies have specifically conducted surveys in rural areas.The purpose of this study is to assess rural residents’knowledge of the COVID-19 and its prevention in China.Methods:A cross-sectional survey study containing 1,426 samples was conducted in Fuqing,China to assess rural residents’knowledge of the COVID-19 and its prevention.Logistic regression was used to identify potential differences in participants’knowledge of COVID-19 and its prevention and control in different population subgroups.Results:The mean and median of residents’knowledge of COVID-19 was 5.53 and 6 points,respectively.The mean and median of residents’knowledge related to self-protection against COVID-19 was 10.34 and 11 points,respectively.Older adults(AOR45e59=2.26,95%CI 1.20 to 4.27;AOR60-69=3.13,95%CI 1.63 to 5.98;AOR70=4.68,95%CI 2.35 to 9.33)were more deficient in knowledge of COVID-19.Those who were better educated and with a higher average annual household income were less likely to be deficient in the knowledge of COVID-19 and knowledge of self-protection against COVID-19.Moreover,those who were single,divorced,or widowed(AOR=1.67,95%CI 1.13 to 2.46)were more deficient in the knowledge of self-protection against COVID-19.Conclusions:Our study suggests that when facing a pandemic like COVID-19,the key is to inform the public to understand simple and effective self-protection measures.Therefore,we call on the govern-ments to give priority to publicity and education on self-prevention measures for the targeted pop-ulations and regions.This is most evident among the vulnerable groups like those who were unmarried,elderly,and those with low education or low income.Similar suggestions may be of use in other countries as well.
基金The National Natural Science Foundation of China(No.71071033)
摘要The impact of risk correlation on firm's investments in information system security is studied by using quantification models combining the ideas of the risk management theory and the game theory. The equilibrium levels of self-protection and insurance coverage under the non- cooperative condition are compared with socially optimal solutions, and the associated coordination mechanisms are proposed. The results show that self-protection investment increases in response to an increase in potential loss when the interdependent risk is small; the interdependent risk of security investments often induce firms to underinvest in security relative to the socially efficient level by ignoring marginal external costs or benefits conferred on others. A subsidy on self-protection investment from the government can help coordinate a firm's risk management decision and, thereby, improve individual security level and overall social welfare.
摘要Objective: to explore the application effect of Orem self-care model in elderly diabetes care. Methods: from November 2019 to October 2021, 70 elderly patients with diabetes in our hospital were randomly divided into 35 patients in each group. The control group received routine nursing, and the observation group received Orem self-nursing mode intervention on the basis of routine nursing. Results: the blood glucose level of the observation group was lower than that of the control group (P<0.05). The self-protection ability and self-management level of observation group were higher than control group (P<0.05). The quality of life in the observation group was higher than that in the control group (P<0.05). The incidence of diabetes-related complications in observation group was lower than that in control group (P<0.05). Conclusion: the application of Orem self-care model in the nursing of elderly diabetes patients can improve patients' self-care ability, self-management ability and living standard, and reduce the incidence of related complications.
摘要In order to solve the problem that the traditional space jamming countermeasure cannot deal with the mainlobe self-protecting jammings,a polarization-space joint mainlobe jamming countermeasure technique based on divided dimensions is proposed.Specifically,the digital beam of each row and column is firstly formed by using dual polarization digital receiving in multi-channel.Then,the polarization-space joint cancellation in both azimuth and elevation dimensions is carried out based on the polarization-space joint difference between the target echo and the jamming,as well as the divided dimension feature of the row and column beams.Finally,the sum and difference beams of the full array in the elevation or azimuth dimension are formed by the beams after jamming cancelling,and the monopulse angle measurement is further employed to obtain target angles.The effectiveness of the proposed technique is verified by simulations,indicating that the self-protecting jamming and multiple mainlobe following jammings can be both cancelled simultaneously with the angle measurement unchanged.
摘要Many developing countries need ecologically clean power sources (PS). The nuclear power plants are such sources. However, a great number of the developing countries do not possess developed large capacity power systems. Moreover, currently in the developing countries, there are no highly skilled personnel to provide construction and reliable and safe operation of the nuclear plants, which are complex and potentially hazardous systems. In some countries, the level of terroristic threat is extremely high. For that reason, there are specific requirements to the nuclear PSs intended for use in the developing countries. In the presented report, the specific requirements which must be met by the NPT proposed for use in developing countries are formulated, basic statements of the SVBR-100 concept are presented, design and principal scheme of the reactor fa-ility are described, major characteristics of SVBR-100 are summarized.
摘要Fast reactors used lead-bismuth eutectic (LBE) and lead as coolants possess very high level of inherent self-protection and passive safety against severe accident. So, population radiophobia can be overcome. That type of reactors can be simultaneously more safely and more cheaply. As all other coolants, LBE and lead coolant (LC) possess the certain virtues and shortcomings. The presented report includes the comparative analysis of characteristic properties of those coolants, their impact on reactor safety, reliability and operating characteristics. The conclusion is made about promising usage of FRs with these coolants in future NP after the experience in operating of the prototypes of such reactors has been obtained.
摘要The article reviews the stable logic analysis model of complex systems or steady multilateral systems with two non-compatibility relations. Energy concept in Physics is introduced to the multilateral systems and used to deal with the multilateral system diseases. By using mathematical reasoning, it is demonstrated that the treatment principle: “Virtual disease is to fill his mother but real disease is to rush down his son” and “Strong inhibition of the same time, support the weak” which due to the “Yin Yang Wu Xing” Theory in Traditional Chinese Medicine (TCM).
摘要By using mathematical reasoning, this paper demonstrates the mathematical intervening principle: “Virtual disease is to fill his mother but real disease is to rush down his son” (虚则补其母, 实则泄其子) and “Strong inhibition of the same time, support the weak” (抑强扶弱) based on “Yin Yang Wu Xing” Theory in image mathematics of Traditional Chinese Mathematics (TCMath). We defined generalized relations and generalized reasoning, introduced the concept of steady multilateral systems with two non-compatibility relations, and discussed its energy properties. Later based on the intervention principle in image mathematics of TCMath and treated the research object of the image mathematics as a steady multilateral system, it has been proved that the mathematical intervening principle is true. The kernel of this paper is the existence and reasoning of the non-compatibility relations in steady multilateral systems, and it accords with the oriental thinking model.
摘要The conflict between safety and economics requirements is peculiar to the present nuclear power (NP). The main point of the conflict is that for traditional type reactors the increase of requirements to safety of nuclear power plants (NPP) worsens their economical characteristics. This is caused by large potential energy accumulated in reactor coolant. In the presented paper the opportunity and expediency of changeover to reactors with heavy liquid-metal coolants (HLMC) in future NP is grounded. First of all, this refers to lead-bismuth coolant (LBC) mastered in the process of operating nuclear submarines (NS) reactors. The reactor facilities (RFs) of that type cannot cause destruction of defense barriers and make possible deterministic elimination of severe accidents with catastrophic radioactivity release. So it will make possible to eliminate the highlighted conflict and reasons for existence of population’s radiophobia. Lead-bismuth fast reactor SVBR-100 with electric power of 100 MWe is the reactor facility of that type. The effect of accumulated in coolant potential energy on safety and economics is considered. Main specific features of SVBR-100 technology providing a high level of inherent self-protection and passive safety are presented.
摘要The degree and characteristics of physical degradation of macro-DNA molecules by common laboratory manipulations are reported. With linearized lambda-phage viral DNA as the model DNA, fragmentation of macro-DNA by various indispensable laboratory manipulations were investigated using a high sensitivity flow cytometric setup. Investigated manipulations included pipetting, vortexing, rocking, freeze-thawing, ultrasonication and ultrafiltration. “Exhaustive counting” of the intact lambda DNA molecules following such manipulations enabled a quantitative assessment of the resulting fragmentation, which also revealed the type of degradation reflected in the fragmentation patterns. The use of high sensitivity flow cytometry was especially suited to investigate the degradation of dilute DNA solutions that may not be suitable for analysis using traditional methods. Notable findings of this study included: the boarderline-size of DNA chains in terms of susceptibility to shear stresses by such manipulations;discernable instability of nicked DNAs;shattering-fragmentation of DNAs by freeze-thawing or ultrasonication;effectiveness of some protection media;marked “self-protection effect” of concentrated DNA solutions. These findings support and refine our traditional knowledge on how to maintain the physical integrity of macro-DNA molecules against inevitable laboratory manipulations.
摘要Objective: to explore the application effect of continuous nursing system in the nursing of discharged patients in intravenous infusion port. Methods: from February 2019 to January 2021, 82 patients with implantable intravenous infusion port were treated in our hospital. According to the parity of admission number, 41 odd cases entered the control group for routine discharge follow-up nursing;An even number of 41 patients entered the experimental group and adopted the continuous nursing system. The maintenance compliance, self-care ability and quality of life of infusion port were compared. Results: the excellent and good rate of maintenance compliance of infusion port in the experimental group was higher than that in the control group (97.56% vs 82.93%);After the intervention, the scores of ESCA and QOL in the experimental group were significantly higher than those in the control group. The test results showed that there was significant difference (P < 0.05). Conclusion: the continuous nursing system for discharged patients in intravenous infusion port can not only improve the maintenance compliance of infusion port, but also improve their self-care ability and quality of life, so it is worth popularizing.
摘要Objective: to explore the effect of all-round nursing on psychological state and self-care ability of patients with myocardial infarction. Methods: 90 patients with myocardial infarction who were hospitalized in Taizhou People's Hospital from January 2018 to December 2020 were selected and randomly selected according to numbers. The patients were divided into two groups. Conventional care was given to the control group, while all-round care was given to the observation group. The change of mentality and self-care ability of the patients in the two groups were compared. Results: through nursing, compared with the control group, the SAS and SDS scores of the observation group were significantly improved, and the scores of self-care ability were all increased (P < 0.05). Conclusion: all-round nursing for patients with myocardial infarction can play a significant role in maintaining more stable psychological mood and improving self-care ability of patients, which is worthy of promotion and use.