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Effect of“Tongdu Yupi Tiaoshen”electroacupuncture on behavioral performance and hippocampal structure and function in chronic fatigue syndrome rats 认领 引用
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作者 QU Yuanyuan FENG Chuwen +5 位作者 SUN Weibo SHAO Yuying LU Jing GUO Shuhao LI Binbin YANG Tiansong 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2026年第3期605-616,共12页
OBJECTIVE:To investigate the effects of electroacupuncture intervention on behavioral performance,hippocampal structure,and function in chronic fatigue syndrome(CFS)rats and to explore the underlying mechanisms.METHOD... OBJECTIVE:To investigate the effects of electroacupuncture intervention on behavioral performance,hippocampal structure,and function in chronic fatigue syndrome(CFS)rats and to explore the underlying mechanisms.METHODS:Specific pathogen free-grade male SpragueDawley rats were randomly allocated into a control group(Con group,n=12)and a modeling group.The latter underwent a 21-d CFS induction via an improved chronic multi-factor compound stress stimulation protocol.Successfully modeled CFS rats were then randomly assigned to a model group(Mod group,n=12)and an electroacupuncture group(EA group,n=12).During the 14-d treatment period,both the Mod and EA groups continued to receive chronic stress stimuli.Rats in the EA group received electroacupuncture at Shenting(GV24)through to Baihui(GV20),with additional stimulation on Dazhui(GV14).Each session lasted 15 min,administered twice daily with a 6-h interval between morning and afternoon treatments.After modeling and treatment,the general semi-quantitative score(GSQS)was used to evaluate the rats'general health,while the Morris water maze test(MWMT),open field test(OFT),and exhaustive treadmill test(ETT)were applied to assess their learning/memory,emotional state,and fatigue levels,respectively(n=12 per group).After the treatment phase,cerebral glucose metabolism was assessed by 1fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG PET/CT)imaging(n=3 per group),while hippocampal cornu ammonis 1(CA1)morphology was examined using hematoxylin-eosin(HE)and Nissl staining(n=3 per group).RESULTS:Behavioral assessments demonstrated that electroacupuncture intervention significantly improved rat performance as measured by GSQS,MWMT,OFT,and Exhaustive Treadmill Test.Both HE and Nissl staining results confirmed that,compared with the blank control group,the model group exhibited abnormal cellular morphology,disorganized arrangement,and reduced Nissl bodies in the hippocampal CA1 region.These pathological alterations were ameliorated in the electroacupuncture group relative to the model group.18F-FDG PET/CT imaging revealed that following treatment,the mean and maximum standardized uptake values(SUV)in the anterior-dorsal and posterior hippocampus were significantly decreased in the Mod group compared to the Con group.In contrast,electroacupuncture treatment significantly increased both SUV-mean and SUV-max in these hippocampal subregions in the EA group relative to the Mod group(all P<0.05).CONCLUSION:Electroacupuncture intervention alleviated cognitive impairment,hippocampal pathological structural changes,and glucose metabolism dysfunction in a rat model of chronic fatigue syndrome induced by an improved chronic multi-factor compound stress stimulation method. 展开更多
关键词 electroacupuncture chronic fatigue syndrome cognitive dysfunction hippocampal structures hippocampal functions
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Landscape and habitat effects on functional and phylogenetic diversity and structure of bird communities in fragmented habitats within an urban landscape,Southwest China 认领 引用
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作者 Yu Liu Yan Wang +6 位作者 Jie Xie Yun Zhu Su Wu Shirui Yu Lingchen Liao Kai Zhang Yu Xu 《Avian Research》 SCIE CAS CSCD 2026年第2期239-248,共10页
Understanding how landscape and habitat characteristics shape species diversity and community structure in fragmented habitats offers insights into the impact of fragmentation on biodiversity.However,relying solely on... Understanding how landscape and habitat characteristics shape species diversity and community structure in fragmented habitats offers insights into the impact of fragmentation on biodiversity.However,relying solely on taxonomic metrics is insufficient to reveal their effects;incorporating functional and phylogenetic dimensions,while accounting for the complex(direct and indirect)relationships between landscape and habitat characteristics,is essential for elucidating the mechanisms of community assembly.By investigating birds in 30 remnant woodlot patches(0.3–290.4 ha)within an urban landscape,Southwest China,during the breeding seasons from 2017 to 2023,we examined the influence of landscape characteristics(i.e.,patch area,isolation,and shape index)and habitat characteristics(including habitat composition and woody plant richness)on their functional and phylogenetic diversity and structure.We recorded 80 bird species,with species richness per patch varying from 14 to 58.Both functional and phylogenetic diversity increased with patch area and woody plant richness but decreased with isolation,which was measured as the percentage of built-up area within a 500 m buffer surrounding patches.Bird communities in most patches showed a trend toward functional and phylogenetic clustering.Functional clustering intensified with increasing isolation but weakened with higher woody plant richness,while phylogenetic clustering weakened as the proportion of croplands increased.The results suggest that landscape and habitat characteristics jointly explain the fragmentation effects on functional and phylogenetic diversity and structure of bird communities,with environmental filtering and niche differentiation-based competition likely acting as context-dependent underlying mechanisms.These findings highlight the importance of protecting and restoring large habitat patches with greater plant richness,expanding green spaces,allotment gardens,or corridors,and minimizing the density of built-up areas across the landscape to maintain functionally or phylogenetically diverse communities in urban environments. 展开更多
关键词 Breeding birds Community structure Environmental filtering Functional diversity Habitat fragmentation Interspecific competition Phylogenetic diversity
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A full information expression model for track irregularity based on stochastic harmonic functions in vehicle-turnout structure stochastic vibration analysis 认领 引用 被引量：1
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作者 Xueyang Tang Xiaopei Cai +1 位作者 Jingmang Xu Fei Yang 《Railway Engineering Science》 EI 2026年第2期349-369,共21页
Turnout irregularity significantly affects the stochastic vibration behavior of vehicle-turnout structures.This study proposes a fitting formula for the turnout irregularity spectrum and develops a turnout irregularit... Turnout irregularity significantly affects the stochastic vibration behavior of vehicle-turnout structures.This study proposes a fitting formula for the turnout irregularity spectrum and develops a turnout irregularity full information expression model(TIFIEM)using a stochastic harmonic function.The model is applied to vehicle-turnout structure stochastic vibration and reliability analysis.Findings suggest that the Hamming window method,with a window length of 4096 points,is optimal for estimating the turnout irregularity spectrum.It is recommended to fit the power spectral density(PSD)using a 5th-order polynomial for better accuracy.The TIFIEM effectively addresses randomness in amplitude,frequency,and phase.An analysis of 250 irregularity samples is sufficient for the desired accuracy.Additionally,the PSD amplitude at various frequency points follows a Chi-square distribution with 2°of freedom.Regions 3-7 m from the tip of the switch rail on the straight switch rail and 53-54 m on the point rail are most susceptible to wear.When the vehicle passes through the turnout at 300 km/h,the reliability of vehicle-turnout structures at the crossing panel decreases to 95.8%. 展开更多
关键词 High-speed railway Vehicle-turnout coupling dynamics Turnout irregularity spectrum Stochastic harmonic function Probability density evolution method
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Network Structure-function Decoupling Underlying the Cognitive Impairment in Ischemic Leukoaraiosis 认领 引用
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作者 Mengxue Wang Wenjuan Huang +5 位作者 Yixin Zhu Tong Lu Zhengsheng Zhang Chunming Xie Zan Wang Qingguo Ren 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2026年第6期717-722,共6页
Cerebral small vessel disease(CSVD)encompasses a spectrum of pathological processes that affect the small arteries,capillaries,and venules of the brain.The neuroimaging features include white matter hyperintensities(W... Cerebral small vessel disease(CSVD)encompasses a spectrum of pathological processes that affect the small arteries,capillaries,and venules of the brain.The neuroimaging features include white matter hyperintensities(WMH),lacunar infarcts,cerebral microbleeds,and enlarged perivascular spaces. 展开更多
关键词 cognitive impairment network structure function decoupling white matter hyperintensities wmh lacunar infarctscerebral microbleedsand pathological processes neuroimaging features cerebral small vessel disease csvd encompasses enlarged perivascular spaces cerebral small vessel disease
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Structure and functional genes associated with carbon,nitrogen,phosphorus,and sulfur cycling processes in periphyton:A comparison between natural and artificial rivers 认领 引用
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作者 Yulu Tian Jiezhang Mo +2 位作者 Jiaxin Liu Chenghao Li Jiahua Guo 《River》 EI CSCD 2026年第2期177-191,共15页
Periphyton in aquatic ecosystems plays vital roles in the elemental cycle process and is vulnerable to anthropogenic interference.However,few studies have explored the elemental cycles of carbon(C),nitrogen(N),phospho... Periphyton in aquatic ecosystems plays vital roles in the elemental cycle process and is vulnerable to anthropogenic interference.However,few studies have explored the elemental cycles of carbon(C),nitrogen(N),phosphorus(P),and sulfur(S)in the natural and artificial rivers using functional genes and microbial interactions in periphyton.In this study,the DNA metabarcoding and the quantitative microbial element cycling smart chip were employed to investigate the differences in the microbial-mediated CNPS cycling processes between the Feng and Zao Rivers,representing natural and artificial rivers,respectively.Compared with the more C-fixation(7.55×104±2.12×104copiesg)and nitrification(4.75×103±2.95×103copiesg)gene abundance in the artificial river,the C-degradation(2.98×104±1.31×104copiesg),denitrification(3.62×104±7.25×103copiesg),and S-reduction(6.66×103±4.26×103copiesg)gene abundance were more in the natural river.In the natural river,the low levels of TN(5.37±0.40 mg/L),DO(3.27±0.32 mg/L),NH4+(0.05±0.05 mg/L),and NO3−(4.36±0.88 mg/L)could support C-degradation,denitrification,and S-reduction.Conversely,higher NO3−levels(8.47±2.13 mg/L)promoted nitrification in the artificial river.Moreover,more bacterial genera were involved in the CNPS cycling in the artificial river,whereas the bacterial-algal relationship was more complex in the natural river.This study could provide insights into the biodiversity and ecological functions of periphyton in different river types. 展开更多
关键词 CNPS cycle ecological function periphyton river type species interactions
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Piezoelectric scaffold for tissue engineering:material,structure,fabrication and function 认领 引用
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作者 Jiye Jia Junwei Shen +3 位作者 Feng Yang Jing Zhang Cijun Shuai Pei Feng 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2026年第2期451-490,共40页
The scaffold for tissue engineering not only requires good biocompatibility,mechanical properties,and appropriate structure,but also should actively participate in biophysical and biochemical processes to accelerate t... The scaffold for tissue engineering not only requires good biocompatibility,mechanical properties,and appropriate structure,but also should actively participate in biophysical and biochemical processes to accelerate tissue repair.A piezoelectric scaffold can generate electrical activity when deformed,which constructs an electrochemical microenvironment for inducing cell signaling pathways and facilitating tissue regeneration,attracting extensive attention in tissue engineering.Herein,piezoelectric materials used in tissue engineering,including piezoelectric ceramics,synthetic piezoelectric polymers,and natural biological piezoelectric materials are systematically summarized,and their advantages and limitations are analyzed.As for the piezoelectric scaffold,the piezoelectric properties mainly stem from the asymmetric crystal structure of materials and the directional arrangement of internal dipoles,which is highly dependent on the fabrication and post-treatment strategies.Therefore,the fabrication techniques of piezoelectric scaffold are detailly introduced,covering both traditional fabrication techniques and additive manufacturing techniques.Besides,rational structural design of the piezoelectric scaffold can alter strain transmission pathways and charge distribution,or add new operational modes to regulate piezoelectric properties.Thereby,the piezoelectric metamaterials,microanostructures,porous structures,heterogeneous structures,and biomimetic structures are comprehensively summarized.Additionally,the functions of piezoelectric scaffold for tissue engineering application in terms of bone regeneration,neural regeneration,antibacterial activity,and intelligent sensing are reviewed.Finally,the challenges and future research directions of the piezoelectric scaffold are discussed. 展开更多
关键词 piezoelectric scaffold fabrication techniques structural design piezoelectric properties tissue engineering
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Mineralized DNA tetrahedron-structured hydrogels:a dual-functional Scaffold for immunomodulation and bone regeneration 认领 引用
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作者 Lan Yao Jiafei Sun +9 位作者 Zhiqiang Liu Jiale Liang Yun Wang Ye Chen Ruiqing Wang Tao He Yichen Yang Yao He Yunfeng Lin Taoran Tian 《Bone Research》 SCIE CAS CSCD 2026年第3期846-860,共15页
Clinical limitations of autografts and allografts have driven advances in bone tissue engineering.Emerging biomaterials offer tunable mechanical and bio-regenerative properties for bone reconstruction.DNA hydrogels ha... Clinical limitations of autografts and allografts have driven advances in bone tissue engineering.Emerging biomaterials offer tunable mechanical and bio-regenerative properties for bone reconstruction.DNA hydrogels have attracted increasing attention due to their extracellular matrix–like architecture and excellent cargo-loading capacity.However,their rapid degradation and limited immunomodulatory activity have hindered their long-term efficacy in bone regeneration.To address these limitations,a mineralized tetrahedral framework nucleic acids(tFNAs)hydrogel(Cap-gel)was engineered to integrate early immunoregulation with sustained osteogenic activity.The stable and programmable spatial structure of tFNAs not only promotes macrophage polarization toward the M2 phenotype by presenting immunomodulatory ligands but also serves as a nucleation template for calcium phosphate crystallization,leading to the formation of nano-mineralized structures with controlled morphology.In vitro,Cap-gel promoted osteogenic differentiation via both immune-dependent and independent pathways,while in vivo,it modulated early immune responses and accelerated bone regeneration in a calvarial defect model.In summary,this study introduces a novel tFNA-based mineralized DNA hydrogel system that integrates immunomodulation and osteogenesis,providing a promising strategy for enhanced bone repair in tissue engineering applications. 展开更多
关键词 mineralized dna hydrogels extracellular matrix architecture mineralized t tetrahedron structured hydrogels immunomodulation immunomodulatory activity bone regeneration bone reconstructiondna hydrogels
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Single-Round Aptamer Discovery Empowered by Machine Learning:Revealing Structure–Function Principles of Target Binding 认领 引用 被引量：1
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作者 Jingjing Yu Hengyi Lin +5 位作者 Zhenhao Long Mingxin Zhang Xiaoqiu Wu Tao Bing Xiaohong Fang Weihong Tan 《CCS Chemistry》 CSCD 2026年第5期2309-2323,共15页
High-throughput sequencing has revolutionized aptamer discovery;however,the process is still limited by the lack of effective methods to extract structural insights from diverse sequences,crucial for aptamer truncatio... High-throughput sequencing has revolutionized aptamer discovery;however,the process is still limited by the lack of effective methods to extract structural insights from diverse sequences,crucial for aptamer truncation,optimization,and molecular design.Herein,we present a machine learning–based framework that decodes aptamer secondary structures directly from single-round selection data,enabling detailed structural insights without the requirement of iterative enrichment.By employing an unsupervised autoencoder clustering(UAE-Clustering)algorithm,our method identified conserved structural motifs in aptamers targeting a model CD8,a key immune regulatory protein.The resulting optimized aptamer exhibited an order-of-magnitude enhancement in binding affinity.We further validated the generalizability of this approach using fibroblast activation protein(FAP),revealing common sequence–structural binding patterns and successfully generating additional optimized aptamers.This approach enabled the rational truncation and optimization of high-affinity aptamers without relying on conventional multi-round selection protocols or experimental structural determination methods such as nuclear magnetic resonance(NMR)spectroscopy or X-ray crystallography.By predicting functional secondary structures directly from primary sequences,our strategy streamlined aptamer engineering and bypassed the need for traditional structure–function analyses.Overall,this strategy not only markedly accelerates aptamer discovery and optimization,but also provides new paradigms for mechanistic investigations of aptamer–target interactions. 展开更多
关键词 aptamer machine learning secondary structures optimization molecular design
Additive Manufacturing of Functionally Graded Lattice Structures for Personalized Below-Knee Prosthetic Dampers 认领 引用
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作者 Guy O'Keefe Naser A.Alsaleh +3 位作者 Mahmoud A.El-Sayed A.Jiménez Sabbah Ataya Khamis Essa 《Chinese Journal of Polymer Science》 SCIE EI CAS CSCD 2026年第1期173-188,I0014,共16页
Functionally graded cellular structures(FGCSs)have a multitude of applications to a wide range of industries.Utilising the ever-progressing technology of additive manufacturing(AM),FGCSs can be applied to control mate... Functionally graded cellular structures(FGCSs)have a multitude of applications to a wide range of industries.Utilising the ever-progressing technology of additive manufacturing(AM),FGCSs can be applied to control material grading and achieve the desired mechanical properties.The current study explores the design and optimisation of FGCSs for AM,with a focus on improving the compression and impact performance of below knee(BK)prosthetic limbs made of thermoplastic polyurethane(TPU).A multiscale research methodology integrating topology optimization(TO),finite element analysis(FEA),and design of experiments(Do E)was adopted to optimise lattice structures in terms of stiffness and lightweight properties.Two-unit cell designs were considered in the study:Schwarz P gyroid and body-centered cubic(BCC).Response surface methodology(RSM)was implemented to analyse the effect of minimum and maximum cell wall thickness,cell size,and unit cell type on the mechanical performance of TPU FGCS structures.The results indicated that a Schwarz P FGCS structure with cell size,minimum and maximum cell wall thickness of 6,0.9 and 2.8 mm,respectively,could be optimal for a compromise between performance and weight.In this optimized case,stiffness and volume fraction values of 684 N/mm and 0.64 were obtained,respectively.The study also presents a proof-of-concept design for a BK prosthetic damper,highlighting the potential of FGCSs to enhance patient comfort,reduce manufacturing costs,and enable personalised designs through 3D scanning and AM.The obtained results could be a step forward towards the incorporation of AM technologies in prosthetics,offering a pathway to lightweight,cost-effective,and functionally tailored solutions. 展开更多
关键词 Additive manufacturing Functionally graded cellular structures Topology optimization Prosthetics
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Stabilization of the double sandwich structure of mercury(ii)porphyrins:Hg⋯Hg⋯Hg interactions and structure–function correlation 认领 引用
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作者 Anindya Sarkar Dolly Chandel +6 位作者 Mirza Nasib Begg Anjani Kumar Pandey Nityananda Dutta Chandrani Pal Mohammad Usman Anindya Datta Sankar Prasad Rath 《Inorganic Chemistry Frontiers》 SCIE EI CAS CSCD 2026年第1期163-174,共12页
A series of stable trinuclear“double sandwich”complexes of mercury(Ⅱ)porphyrins with linear Hg3 cores has been stabilized successfully utilizing both flexible and rigid porphyrin dimer frameworks.The gross structur... A series of stable trinuclear“double sandwich”complexes of mercury(Ⅱ)porphyrins with linear Hg3 cores has been stabilized successfully utilizing both flexible and rigid porphyrin dimer frameworks.The gross structural patterns are similar:two terminal Hg(Ⅱ)centers are above and below the porphyrin rings,whereas the middle Hg(Ⅱ)center is sandwiched between the two rings.The mercury–nitrogen distances are quite different in the complexes.Mercurophilic interactions play a crucial role in stabilizing this unique structure,with a linear Hg⋯Hg⋯Hg unit overcoming the inherent instability arising from two coplanar aromatic(porphyrin)rings placed exactly on top of each other with eclipsed conformations,a hallmark of the double sandwich complexes reported here.Interestingly,the strongest mercurophilic interactions(with Hg⋯Hg distances of 3.1251(11)Åand 3.1333(16)Å)are observed with the highly flexible ethane-bridged porphyrin dimer.Extensive DFT calculations demonstrate that the mercurophilic interaction is evident when relativistic and dispersion effects are included and the distances are also in excellent agreement with the X-ray structures of the complexes.NBO and QTAIM analyses revealed distinct bond paths and bond critical points(BCPs)that are commonly recognized as key indicators of mercurophilic interactions.The absorption(with an MMLCT band at∼350 nm)and photoluminescence properties of the complexes display direct correlation with the strength of the Hg⋯Hg interactions.Fluorescence decays at the blue end(related to the mercurophilic interactions)of the emission spectra are faster than those at the red end(associated with ligand emission)for all the complexes at both 298 K and 77 K. 展开更多
关键词 mercurophilic interactions porphyrin ringswhereas mercury II porphyrins structure function correlation double sandwich structure flexible rigid porphyrin dimer frameworksthe mercury nitrogen distances DFT calculations
Structure insight into FtsZ function maintaining under acid stress of Streptococcus mutans 认领 引用
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作者 Yuxing Chen Yongliang Li +9 位作者 Jiahao Niu Liuchang Yang Yaqi Chi Xue Cai Fengjiao Xin Jie Zhang Xianyang Fang Yiqin Gao Manas Mondal Xiaoyan Wang 《International Journal of Oral Science》 SCIE CAS CSCD 2026年第1期90-102,共13页
Understanding the acid resistance mechanism of S.mutans is crucial for preventing dental caries.FtsZ is the core protein for cell division in bacteria that can polymerize into Z-rings and drive cytokinesis.Our previou... Understanding the acid resistance mechanism of S.mutans is crucial for preventing dental caries.FtsZ is the core protein for cell division in bacteria that can polymerize into Z-rings and drive cytokinesis.Our previous study revealed that the FtsZ in S.mutans(SmFtsZ) has higher self-assembly and GTPase activity under acidic stress,which may be responsible for acid resistance and ca riogenesis of S.mutans.However,the functional structure mechanism of SmFtsZ under low pH conditions is still unclear.Here,we further reported the crystal structure of S.mutans FtsZ,revealing a unique lateral interface.Through protein polymerization and GTPase activity assay,we experimentally demonstrated that the mutation of Arg68 on this lateral interface significantly reduced the functional activity of FtsZ in an acidic environment.The phenotype assay and rat caries model further showed that the mutation of Arg68 effectively inhibited the acid resistance of S.mutans and the occurrence and progress of dental caries in vivo.By employing a molecular dynamics simulation analysis,we conclude that the mutation of Arg68 disrupts the conformation change necessary for SmFtsZ polymerization under acidic conditions.Our study proposes a novel mechanism to maintain FtsZ function in bacteria and could be a potential target for antimicrobial drugs to inhibit the growth of S.mutans in acidic environments. 展开更多
关键词 ca riogenesis FtsZ acid resistance dental cariesftsz acidic stress cell division functional structure mechanism low ph conditions
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Short-term silicone oil tamponade on retinal structure and function in rhegmatogenous retinal detachment:a randomized controlled trial 认领 引用
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作者 Zi-Ye Chen Yu-Qing Wu +7 位作者 Bao-Yi Liu Yuan Ma Zhuang-Ling Lin Run-Ping Duan Lan Jiang Chinling Tsai Zhuo-Jun Xu Tao Li 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2026年第1期83-89,共7页
AIM:To investigate the effects of shortening the duration of silicone oil tamponade on retinal structure and function in patients undergoing silicone oil removal(SOR)after surgery for primary rhegmatogenous retinal de... AIM:To investigate the effects of shortening the duration of silicone oil tamponade on retinal structure and function in patients undergoing silicone oil removal(SOR)after surgery for primary rhegmatogenous retinal detachment(RRD).METHODS:A total of 58 eligible patients were enrolled and randomly assigned to two groups based on tamponade duration:the short-term group(30-45d)and the conventional group(≥90d).Comprehensive evaluations were performed before and after SOR,including slitlamp examination,best-corrected visual acuity(BCVA)measurement,intraocular pressure(IOP)testing,optical coherence tomography(OCT),optical coherence tomography angiography(OCTA),microperimetry,electroretinography(ERG),and visual evoked potential(VEP)assessment.RESULTS:A total of 33 patients(23 males and 10 females;33 eyes)were enrolled in the short-term SO tamponade group with mean age of 52.45±9.35y,and 25 patients(15 males and 10 females;25 eyes)were enrolled in the conventional SO tamponade group with mean age of 50.80±12.06y.Compared with the conventional group,the short-term silicone oil tamponade group had a significantly lower incidence of silicone oil emulsification and cataract progression,with no significant difference in retinal reattachment success rate.Structurally,short-term tamponade was associated with increased thickness of the retinal ganglion cell layer(RGCL)in the nasal and superior macular regions and improved recovery of superficial retinal vascular density in these areas.Functionally,the shortterm group showed better BCVA and retinal sensitivity both before and 1mo after SOR;additionally,the P100 amplitude in VEP tests was significantly increased in this group.CONCLUSION:Shortening the duration of silicone oil tamponade effectively reduces damage to retinal structure and function without compromising the success rate of retinal reattachment in patients with primary RRD. 展开更多
关键词 silicone oil tamponade rhegmatogenous retinal detachment silicone oil removal retinal structure retinal function prognosis
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An efficient algorithm for generating perfect special quasirandom structures with many-body correlation functions and its application to the Kronig-Penney model 认领 引用
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作者 Tian-Ze Li Chang-Chun He Xiao-Bao Yang 《Chinese Physics B》 SCIE EI CAS CSCD 2026年第7期268-278,共11页
The special quasirandom structure(SQS)method provides an ideal representation of disordered structures.However,it is still a challenge to generate structures that perfectly satisfy the constraints of correlation funct... The special quasirandom structure(SQS)method provides an ideal representation of disordered structures.However,it is still a challenge to generate structures that perfectly satisfy the constraints of correlation functions,especially for manybody interactions.Taking one-dimensional systems as an example,we develop an efficient SQS construction algorithm for multi-component materials based on De Bruijn sequences,which can be extended to systems with higher dimensions and more components.The SQSs constructed by our algorithm are shown to universally satisfy all the constraints of 1∼nbody interactions,and the numbers of consecutive identical-atom subsequences follow a unified counting rule.Based on the Kronig-Penney model,we have systematically investigated the impact of structural disorder on electronic properties.As the cell size increases,there are the same trends in the electronic structures obtained from SQSs and fully random structures,while SQSs display markedly faster convergence and significantly reduced fluctuations.We demonstrate that SQS provides a reliable and efficient finite-size representation for electronic-structure calculations of disordered systems. 展开更多
关键词 disordered structure special quasirandom structure De Bruijn sequence Kronig–Penney model
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Plasma-engineered interfacial built-in electric fields in wood-templated heterostructures for synergistic bifunctional electrocatalysis 认领 引用
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作者 Chang Liu Guijuan Wei +3 位作者 Zaixing Zheng Xixia Zhao Xin Zhao Honglei Chen 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2026年第5期123-133,I0004,共11页
Realizing the multi-species adsorption in electrocatalysis requires precise control of interfacial electronic structures at heterojunctions,yet this remains a fundamental challenge under industrial operational conditi... Realizing the multi-species adsorption in electrocatalysis requires precise control of interfacial electronic structures at heterojunctions,yet this remains a fundamental challenge under industrial operational conditions.Here,we develop a gradient plasma nano-engineering strategy to construct Ru-Ni@Ni2P heterostructures within hierarchically porous P-doped carbonized wood(PCW)monoliths.This approach simultaneously achieves plasma-induced phase transformation/phosphidation and the creation of a continuous built-in electric field(BIEF)at the heterointerface.Ultraviolet photoelectron spectroscopy and Kelvin probe force microscopy confirm that a work function difference of 0.15 eV drives spontaneous electron transfer from Ru-Ni to Ni2P,generating a robust BIEF with a 42.3 mV potential gradient.This BIEF induces a synergistic optimization of the adsorption energetics for multiple reactive species(H and HMF).Specifically,the catalyst achieves an ultralow hydrogen evolution overpotential(96 mV at 100 mA cm-2)with near-idealΔGH*(0.04 eV),and concurrently drives efficient HMF oxidation at 1.35 V(100 m A cm-2),230 m V below the oxygen evolution potential,via an optimized reaction pathway(HMF→HMFCA→FFCA→FDCA).The native wood microstructure and plasma-sculpted nanoarrays ensure efficient mass transport and BIEF-enhanced bubble repulsion,yielding exceptional durability.This work establishes a general paradigm based on interfacial electric field programming within sustainable scaffolds and offers a transformative platform for energy-efficient electrochemical refining and hydrogen production. 展开更多
关键词 Built-in electric field Interface engineering Work function regulation 5-Hydroxymethylfurfural Hydrogen evolution
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Multifunctional CNT/cellulose-BN/PVA Composites Integrating Dual-continuous Network Structure with Gradient Conductivity for Electromagnetic Interference Shielding and Joule Heating 认领 引用
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作者 Xiao-Rui Wang Ting-Ting Liu +2 位作者 Cheng-Hua Cui Xin Xu Liang-Qing Zhang 《Chinese Journal of Polymer Science》 SCIE EI CAS CSCD 2026年第3期803-812,I0015,共10页
In this study,an architecture featuring a gradient conductive network structure and three-dimensional dual-continuous network structure is constructed in a carbon nanotubes/cellulose-boron nitride/poly(vinyl alcohol)(... In this study,an architecture featuring a gradient conductive network structure and three-dimensional dual-continuous network structure is constructed in a carbon nanotubes/cellulose-boron nitride/poly(vinyl alcohol)(CNT/cellulose-BN/PVA)composite.Using cellulose aerogel as a template,CNT were incorporated into the cellulose template by vertically impregnating the CNT suspension.Following the impregnation of BN/PVA and high-pressure compression,three-dimensional dual-continuous network structure was successfully constructed in the CNT/cellulose-BN/PVA composite.The comprehensive performance of the composite,including electromagnetic interference(EMI)shielding and Joule heating performance,was investigated.The results indicate that the total EMI shielding effectiveness(SE)for the CNT/cellulose-BN/PVA composite reveals similar values for electromagnetic waves incident from different directions,but totally different shielding mechanisms.For the CNT/cellulose-BN/PVA composite with three impregnation cycles of CNT,the EMI SE values exceeded 39 dB for electromagnetic waves incident from both the high-and low-CNT-content sides.93%of the microwaves were reflected when electromagnetic waves were incident from the high-CNT-content side,while the reflection coefficient decreased to 0.44 for the transverse direction.In addition,the construction of the dual-continuous network structure enabled the composite to exhibit both excellent electrical conductivity and good thermal conductivity simultaneously,endowing the material with good Joule heating performance.CNT/cellulose-BN/PVA composite films have significant potential for application as EMI shielding materials in extremely cold weather. 展开更多
关键词 Cellulose Dual-continuous network structure Gradient conductivity Electromagnetic interference shielding Joule heating
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Periodic multilayer functionally graded structure of Ni-NbMoTa high-entropy alloy composition materials via laser cladding deposition 认领 引用
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作者 Hang Zhang Xiaoyu Sun +6 位作者 Yaoyao He Yizhen Zhao Zihao Chen Xin Guo Qingyu Li Shaokun Ji Dichen Li 《Additive Manufacturing Frontiers》 CAS CSCD 2026年第1期193-199,共7页
As the demand for high-performance components in aerospace and other advanced industries continues to increase,the demand for composite structures that combine functionality,structural integrity,and superior performan... As the demand for high-performance components in aerospace and other advanced industries continues to increase,the demand for composite structures that combine functionality,structural integrity,and superior performance increases.In this study,laser cladding deposition(LCD) was employed to fabricate a gradient structure based on a Ni-NbMoTa refractory high-entropy alloy(HEA),resulting in the development of a novel functionally graded material(FGM).An interlayer printing strategy was implemented to deposit Ni and NbMoTa alloys via distinct processing routes,enabling the construction of a three-dimensional gradient architecture.The resulting Ni-NbMoTa HEA FGMs exhibited no macroscopic or microscopic cracks within the gradient transition zone.The crystal structure consisted of a dual-phase solid solution comprising body-centered cubic(BCC) and face-centered cubic(FCC) phases.The average grain size and dendrite arm spacing in the transition zone were approximately 20 and 3 μm,respectively.The microhardness of the Ni-NbMoTa FGMs reached 584.5 ±39.3 HV,showing a clear correlation between hardness and Ni content.Compared with monolithic NbMoTa fabricated using LCD,the Ni-NbMoTa FGMs demonstrated significantly improved room-temperature mechanical properties,with compressive yield strength,ultimate compressive strength,and compressive strain reaching 1096 MPa,1445.4 MPa,and 18.2 %,respectively.These findings indicate that the addition of Ni effectively enhances the additive manufacturability of the Ni-NbMoTa gradient refractory HEA by promoting grain refinement and improving both strength and ductility. 展开更多
关键词 Laser cladding deposition High-entropy alloy Interlayer printing Gradient structure
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A data-driven integrated optimization method of macroscopic topology and microscopic configuration for the graded functional cellular structures 认领 引用
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作者 Yu Guo Yijie Lu +2 位作者 Zhengwei Zhang Yanguo Zhou Hui Liu 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第2期473-495,共23页
In the topology optimization of the multiscale structure,how to ensure the connectivity between adjacent microstructures,how to control the design space of microstructures,and how to reduce the amount of calculation a... In the topology optimization of the multiscale structure,how to ensure the connectivity between adjacent microstructures,how to control the design space of microstructures,and how to reduce the amount of calculation and improve calculation efficiency are three basic challenging issues currently faced.To this end,this paper proposes a data-driven approach to achieve the integrated optimization of macroscopic topology and microscopic configuration of the graded functional cellular structures.At the macro level,a topological description function is introduced to realize the topological control of the macrostructure.At the micro level,several cutting functions are used to realize the control of the configuration and size of the microstructure.The integrated optimization design of macro and micro cellular structures can be realized.Based on the computational homogenization method and numerical integration technology,an optimization problem independent offline microstructure database is established at the microscopic scale,where the relationship between the equivalent elastic parameters,relative pseudo-density,and design variables of the microstructure is stored.Based on this offline database,the entire topology optimization process is completed only on a macro scale,which greatly reduces the amount of calculation and improves calculation efficiency.In addition,implicit geometric modeling of full-scale cellular structures can be achieved using the reconstruction technique introduced in this work,which ensures smooth connection between adjacent microstructures.Finally,numerical examples are used to verify the effectiveness of the algorithm and the superiority of gradient cellular structures compared with single-scale structures. 展开更多
关键词 Graded cellular structure Integrated optimization Data-driven Computational homogenization M-VCUT Level set method
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Design of dual-network structure based on coordination bonds and hydrogen bonds for high-performance multifunctional flexible gel absorbers 认领 引用
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作者 Xinyue Xie Zijing Li +3 位作者 Shusheng Wang Geng Chen Limin Zhang Hongjing Wu 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2026年第2期693-703,共11页
The emergence of precision electronic devices and wearable electronic products urgently requires high-performance multifunctional electromagnetic wave(EMW)absorbers to meet the applicability and versatility in various... The emergence of precision electronic devices and wearable electronic products urgently requires high-performance multifunctional electromagnetic wave(EMW)absorbers to meet the applicability and versatility in various applications.Herein,a dual-network(DN)gel was successfully prepared using acrylamide and sodium lignosulphonate as the basic units by simple chemical cross-linking and physical cross-linking methods.Specifically,the hydrogel forms two types of cross-linking networks through metal coordination and hydrogen bonding.Benefiting from the combined effects of dipole polarization and conductivity loss,the gel achieves an effective absorption bandwidth(EAB)of 6.74 GHz at a thickness of only 1.89 mm,demonstrating excellent EMW absorption performance.In addition,this unique structural configuration endows the EMW absorber with multifunctional features,such as remarkable tensile strength,good environmental compatibility,ultraviolet(UV)resistance,and excellent adhesion.Integrating multiple functional features into the EMW gels displays a broad application prospect in a variety of application scenarios.This research reveals the significance of DN structure design in the electromagnetic wave absorption(EWA)performance of gel-based materials,providing a substantial foundation for the multifunctional design of gel-based absorbers. 展开更多
关键词 electromagnetic wave absorbers dual-network structure polarization loss hydrogen bonds coordination bonds multifunc-tional characteristics
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A review on microstructure,mechanical and functional properties of ultrafine-grained magnesium alloys processed by high-pressure torsion 认领 引用
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作者 Ruirui Yin Junbin Hou +7 位作者 Ding Li Wanting Sun Xiaoguang Qiao Xinxiong Xiao Xiongwei Liang Da Zeng Ruslan Z.Valiev Mingyi Zheng 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2026年第4期13-51,共39页
Magnesium(Mg)alloys are the lightest metallic structural materials,holding significant potential for automotive,aerospace,electronic,and biomedical applications.However,their broader adoption is impeded by inherent dr... Magnesium(Mg)alloys are the lightest metallic structural materials,holding significant potential for automotive,aerospace,electronic,and biomedical applications.However,their broader adoption is impeded by inherent drawbacks,including low strength,limited ductility,and poor corrosion resistance.High-pressure torsion(HPT)has proven effective in generating ultrafine-grained(UFG)Mg alloys,resulting in substantial property enhancements.This review critically assesses the microstructure evolution of HPT-processed Mg alloys covering not only grain refinement but also solute segregation,texture evolution,dissolution and precipitation of second phases,allotropic transformation,crystalto-amorphous transition and nanocrystallization.In particular,it elucidates the impact of these microstructures’evolutions on mechanical properties,including yield strength,hardness and superplasticity.Additionally,the review discusses the improvements in the addresses the functional augmentation of HPT-processed Mg alloys,specifically corrosion behavior,hydrogen storage capabilities,and biomedical performance. 展开更多
关键词 Magnesium(Mg)alloys High-pressure torsion(HPT) Microstructure evolution Mechanical properties Functional properties
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TRPV1:from structure to function—a multidimensional target for therapeutic advances 认领 引用
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作者 Yi LIU Fuqin DUAN +3 位作者 Runpeng LIN Subinuer SHABUERJIANG Fan YANG Aerziguli AIERKEN 《Journal of Zhejiang University-SCIENCE B》 SCIE CAS CSCD 2026年第1期1-22,共22页
Transient receptor potential vanilloid subtype 1(TRPV1),a polymodally activated,calcium-permeable non-selective cation channel,is broadly present in all parts of the body,with notable expression in the nociceptive neu... Transient receptor potential vanilloid subtype 1(TRPV1),a polymodally activated,calcium-permeable non-selective cation channel,is broadly present in all parts of the body,with notable expression in the nociceptive neurons.Both physiological and pathological functions rely heavily on this ion channel,mediating responses to a variety of stimuli and contributing to the maintenance of bodily homeostasis.Its unique ability to respond to temperature changes,chemical ligands,and voltage fluctuations positions TRPV1 as a key target in understanding and modulating normal bodily functions,in addition to diagnosing and treating diseases.This review synthesizes current knowledge on the structure,gating mechanisms,and physiological and pathological roles of TRPV1,highlighting its potential as a therapeutic target across multiple disease states.By providing a comprehensive overview of the multifaceted functions of TRPV1,this review aims to inform and inspire future research,finally contributing to the advancement of new therapeutic techniques focusing on TRPV1 to enhance human health. 展开更多
关键词 Transient receptor potential vanilloid subtype 1(TRPV1) Structure Gating mechanism Therapeutic target
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