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Syzygium cumini(L.)Skeels:A review of its phytochemical constituents and traditional uses 认领 引用 被引量：10
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作者 Muniappan Ayyanar Pandurangan Subash-Babu 《Asian Pacific Journal of Tropical Biomedicine》 CAS 2012年第3期240-246,共7页
Syzygium cumini(S.cumini)(L.) Skeels(jambolan) is one of the widely used medicinal plants in the treatment of various diseases in particular diabetes.The present review has been primed to describe the existing data on... Syzygium cumini(S.cumini)(L.) Skeels(jambolan) is one of the widely used medicinal plants in the treatment of various diseases in particular diabetes.The present review has been primed to describe the existing data on the information on botany,phytochemical constituents,traditional uses and pharmacological actions of 5.cumini(L.) Skeels(jambolan).Electronic database search was conducted with the search terms of Eugenia jambolana,S.cumini,jambolan,common plum and java plum.The plant has been viewed as an antidiabetic plant since it became commercially available several decades ago.During last four decades,numerous folk medicine and scientific reports on the antidiabetic effects of this plant have been cited in the literature.The plant is rich in compounds containing anthocyanins,glucoside,ellagic acid,isoquercetin,kaemferol and myrecetin.The seeds are claimed to contain alkaloid,jambosine,and glycoside jambolin or antimellin,which halts the diastalic conversion of starch into sugar.The vast number of literatures found in the database revealed that the extracts of different parts of jambolan showed significant pharmacological actions.We suggest that there is a need for further investigation to isolate active principles which confer the pharmacological action.Hence identification of such active compounds is useful for producing safer drugs in the treatment of various ailments including diabetes. 展开更多
关键词 Syzygium cumini Medicinal uses Myrtaceae Phytochemistry Traditional uses Jambolan Common plum Java plum Eugenia jambolana
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Effects of the Syzygium aromaticum L. extract on antioxidation and inhibition of matrix metalloproteinase in human dermal fibroblast 认领 引用 被引量：1
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作者 Da Eun Kim Yeon Sil Hwang +3 位作者 Bo Yoon Chang Dae Sung Kim Hyoung Kwon Cho Sung Yeon Kim 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2019年第2期53-59,共7页
Objective: To investigate cosmetic potential of Syzygium aromaticum L.(S. aromaticum L.) and to determine its antioxidant and anti-wrinkling effects. Methods: Using highperformance liquid chromatography, eugenol compo... Objective: To investigate cosmetic potential of Syzygium aromaticum L.(S. aromaticum L.) and to determine its antioxidant and anti-wrinkling effects. Methods: Using highperformance liquid chromatography, eugenol component was quantitated. The antioxidant activity of S. aromaticum L. was analyzed by 2,2-diphenyl-1-picrylhydrazyl radical scavenging and superoxide dismutase like activities. To determine cell viability, elastase and matrix metalloproteinase-1(MMP-1) activity, human dermal fibroblasts(HS68) were treated with S. aromaticum L. The inhibitory effect of S. aromaticum L. on tumor necrosis factor alpha induced MMPs expression in HS68 was analyzed by realtime-PCR. Results: The eugenol content was confirmed in S. aromaticum L. S. aromaticum L. was observed to have high 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity and superoxide dismutase like activity. S. aromaticum L. had no cytotoxicity against the HS68 and dose-dependently increased elastase inhibition. Moreover, S. aromaticum L. significantly decreased MMP-1 content and inhibited gene levels of MMP-1, MMP-2, MMP-3 and MMP-9. Conclusions: The findings suggest that S. aromaticum L. has great potential as a cosmeceutical ingredient with antioxidant and antiwrinkling effects. 展开更多
关键词 Syzygium aromaticum L Antioxidant Anti-aging Elastase Matrix metalloproteinase-1
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Inhibition of Escherichia coli nitroreductase by the constituents in Syzygium aromaticum 认领 引用 被引量：1
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作者 CHEN Lu CHEN Xi +5 位作者 BAI Yue ZHAO Zi-Nan CAO Yun-Feng LIU Li-Kun JIANG Tao HOU Jie 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2022年第7期506-517,共12页
Gut bacterial nitroreductases play an important role in reduction of various nitroaromatic compounds to the corresponding N-nitroso compounds,hydroxylamines or aromatic amines,most of which are carcinogenic and mutage... Gut bacterial nitroreductases play an important role in reduction of various nitroaromatic compounds to the corresponding N-nitroso compounds,hydroxylamines or aromatic amines,most of which are carcinogenic and mutagenic agents.Inhibition of gut nitroreductases has been recognized as an attractive approach for reducing mutagen metabolites in the colon,so as to prevent colon diseases.In this study,the inhibitory effects of 55 herbal medicines against Escherichia coli(E.coli)nitroreductase(EcNfsA)were examined.Compared with other herbal extracts,Syzygium aromaticum extract showed superior inhibitory potency toward EcNf-sA mediated nitrofurazone reduction.Then,the inhibitory effects of 22 major constituents in Syzygium aromaticum against EcNfsA were evaluted.Compared with other tested natural compounds,ellagic acid,corilagin,betulinic acid,oleanic acid,ursolic acid,urolith-in M5 and isorhamnetin were found with strong to moderate inhibitory effect against EcNfsA,with IC50 values ranging from 0.67 to 28.98 mol·L−1.Furthermore,the inhibition kinetic analysis and docking simulation demonstrated that ellagic acid and betulinic acid potently inhibited EcNfsA(Ki<2μmol·L−1)in a competitively inhibitory manner,which created strong interactions with the catalytic triad of EcNfsA.In summary,our findings provide new scientific basis for explaining the anti-mutagenic activity of Syzygium aromaticum,where some newly identified EcNfsA inhibitors can be used for developing novel agents to reduce the toxicity induced by bacteri-al nitroreductase. 展开更多
关键词 Gut bacterial nitroreductase EcNfsA inhibitor Syzygium aromaticum Anti-mutagenic activity
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Diploid wax apple(Syzygium samarangense)genome identified NAC genes regulating fruit development 认领 引用
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作者 Junyu Zhang Zhidong Li +6 位作者 Yufan Liang Shuang He Guilian Guo Shuting Yang Fei Chen Yinhua Chen Wenquan Wang 《Horticulture Research》 SCIE CSCD 2024年第3期376-378,共3页
Dear Editor,Syzygium samarangense,the wax apple,is a tropical plant species belonging to the eudicot Myrtaceae family.Common names include the wax apple,Java apple,rose apple,and wax jambu.Its native habitat is south ... Dear Editor,Syzygium samarangense,the wax apple,is a tropical plant species belonging to the eudicot Myrtaceae family.Common names include the wax apple,Java apple,rose apple,and wax jambu.Its native habitat is south Asia and Southeast Asia,and it was introduced to Chinese Taiwan in the 17th century and is now widely cultivated in the tropics. 展开更多
关键词 diploid eudicot myrtaceae fruit development Syzygium samarangense NAC genes wax appleis wax jambuits genome
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Larvicidal efficacies and chemical composition of essential oils of Pinus sylvestris and Syzygium aromaticum against mosquitoes 认领 引用 被引量：5
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作者 Kehinde Adenike Fayemiwo Monsuru Adebayo Adeleke +2 位作者 Ovie Princewill Okoro Shola Hezekiah Awojide Ilias Olufemi Awoniyi 《Asian Pacific Journal of Tropical Biomedicine》 CAS 2014年第1期30-34,共5页
Objective:To assess the chemical composition and mosquito larvicidal potentials of essential oils of locally sourced Pinus sylvestris(P.sylvestris)and Syzygium aromatkum(S.aromaticum)against Aedes aegypti(A.aegypti)an... Objective:To assess the chemical composition and mosquito larvicidal potentials of essential oils of locally sourced Pinus sylvestris(P.sylvestris)and Syzygium aromatkum(S.aromaticum)against Aedes aegypti(A.aegypti)and Culex quinquefasciatus(C.quinquefasciatus).Method:The chemical composition of the essential oils of both plants was determined using GCMS while the larvicidal bioassay was carried out using different concentrations of the oils against the larvae of A.aegypti and C.quinquefasciatus in accordance with the standard protocol.Results:The results as determined by GC-MS showed that oil of S.aromaticum has eugenol(80.5%)as its principal constituent while P.sylvestris has 3-Cyclohexene-1-methanol,.alpha.,.alpha.4-trimethyl(27.1%)as its dominant constituent.Both oils achieved over 85%larval mortality within24 h.The larvae of A.aegypti were more susceptible to the oils[LC50(S.aromaticum)=92.56 mg/L,LC50(P.sylvestris)=100.39 mg/L]than C.quinquefasciatus[LC50(S.aromaticum)=124.42 mg/L;LC50(P.sylvestris)=128.00 mg/L].S.aromaticum oil was more toxic to the mosquito larvae than oil of P.sylvatris but the difference in lethal concentrations was insignificant(P>0.05).Condusioii:The results justify the larvicidal potentials of both essential oils and the need to incorporate them in vector management and control. 展开更多
关键词 Essential oils Chemical analysis Larvicides Mosquitoes Pinus sylvestris Syzygium aromaticum
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A comparative study of conventional and supercritical fluid extraction methods for the recovery of secondary metabolites from Syzygium campanulatum Korth 认领 引用 被引量：4
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作者 Abdul Hakeem MEMON Mohammad Shahrul Ridzuan HAMIL +5 位作者 Madeeha LAGHARI Fahim RITHWAN Salman ZHARI Mohammed Ali Ahmed SAEED Zhari ISMAIL Amin Malik Shah Abdul MAJID 《Journal of Zhejiang University-SCIENCE B》 SCIE CAS CSCD 2016年第9期683-691,共9页
Syzygium campanulatum Korth is a plant, which is a rich source of secondary metabolites （especially flavanones, chalcone, and triterpenoids）. In our present study, three conventional solvent extraction （CSE） techn... Syzygium campanulatum Korth is a plant, which is a rich source of secondary metabolites （especially flavanones, chalcone, and triterpenoids）. In our present study, three conventional solvent extraction （CSE） techniques and supercritical fluid extraction （SFE） techniques were performed to achieve a maximum recovery of two flavanones, chalcone, and two triterpenoids from S. campanulatum leaves. Furthermore, a Box-Behnken design was constructed for the SFE technique using pressure, temperature, and particle size as independent variables, and yields of crude extract, individual and total secondary metabolites as the dependent variables. In the CSE procedure, twenty extracts were produced using ten different solvents and three techniques （maceration, soxhletion, and reflux）. An enriched extract of five secondary metabolites was collected using n-hexane：methanol （1：1） soxhletion. Using food-grade ethanol as a modifier, the SFE methods produced a higher recovery （25.5%-84.9%） of selected secondary metabo- lites as compared to the CSE techniques （0.92%-66.00%）. 展开更多
关键词 Syzygium campanulatum Supercritical fluid extraction Conventional solvent extractions Flavanones Chalcone Triterpenoids
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Cardio- and hepato-protective potential of methanolic extract of Syzygium cumini(L.) Skeels seeds:A diabetic rat model study 认领 引用 被引量：3
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作者 Sumaiya Nahid Kishor Mazumder +3 位作者 Zillur Rahman Saiful Islam Md. Humayun Rashid Philip Grey Kerr 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2017年第2期126-133,共8页
Objective: To evaluate the effect of methanolic extract of Syzygium cumini(L.) Skeels(S. cumini) seeds on the major organs in an animal model of diabetes through biochemical and histopathological studies.Methods: The ... Objective: To evaluate the effect of methanolic extract of Syzygium cumini(L.) Skeels(S. cumini) seeds on the major organs in an animal model of diabetes through biochemical and histopathological studies.Methods: The methanolic extracts of S. cumini seeds(100 and 200 mg/kg body weight) were administered to alloxan-induced diabetic rats daily, with fasting blood glucose levels being measured by glucometry at one-day interval for a duration of two weeks. Biochemical assays to evaluate changes in the functions of the heart, liver,pancreas and kidney were carried out. Histopathological changes in the diabetic rat organs(pancreas, liver, heart, kidney and spleen) were also observed after the 14 days of treatment with the extracts.Results: Oral administration of methanolic extracts of S. cumini seeds(100 and 200 mg/kg body weight), with gliclazide as a positive control(25 mg/kg), showed beneficial effects including lowering blood glucose levels(P < 0.001), improved heart and liver functions, and hyperlipidemia due to diabetes. At 200 mg/kg, the extracts reversed cardiac and liver damage caused by alloxan.Conclusions: In addition to the anti-hyperglycemic activity of methanolic extracts of S. cumini seeds, the extracts demonstrates potential to minimize cardiac and hepatic complications. 展开更多
关键词 Syzygium cumini seeds Diabetes Cardioprotection Hepatoprotection
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Acaricidal activity of different extracts from Syzygium cumini L.Skeels(Pomposia) against Tetranychus urticae Koch 认领 引用 被引量：5
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作者 Abd El-Moneim MR Afify Hossam S El-Beltagi +1 位作者 Sayed A Fayed Emad A Shalaby 《Asian Pacific Journal of Tropical Biomedicine》 CAS 2011年第5期359-364,共6页
Objective:To investigate the acaricidal activity of different extracts from Syzygium cumini(S.cumini)(Pomposia)againsst Tetranyckus urticae Koch(71 urticae)and the biochemical changes in antioxidants enzymes.Methods:S... Objective:To investigate the acaricidal activity of different extracts from Syzygium cumini(S.cumini)(Pomposia)againsst Tetranyckus urticae Koch(71 urticae)and the biochemical changes in antioxidants enzymes.Methods:Six extracts of S.cumini(Pomposia)at concentrations of 75,150 and 300μg/mL were used to control T.urticae(Koch).Results:The ethanol extract showed the most efficient acaricidal activity agent against T.urticae(98.5%)followed by hexane extract(94.0%),ether and ethyl acetate extract(90.0%).The LC50values of the promising extract-were 85.0,101.0,102.0 and 98.0μ/mL,respectively.The activities of enzymes including ascorbate peroxidase(APX),peroxidase(POD),superoxide dismutase(SOD)and catalase(CAT)in susceptible mites were increased.The activities of all antioxidant enzymes reach the maximum value in mites at LC50with ethanol and ethyl acetate extracts,respectively.Conclusions:The extract of S.cumini has acaricidal acivity against T.urticae,and the ethanol extract is the most efficient. 展开更多
关键词 Tetranychus urticae Syzygium cumini Successive extracts Antioxidant enzymes
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Morphological characterization, antioxidant capacity and diversity of Syzygium cumini trees from Sri Lanka 认领 引用 被引量：1
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作者 Prasajith Kapila Dissanayake Wekumbure Gedara Chandima Wekumbura +1 位作者 Alge Watage Wijeratne Douglas Siril Abeywickrama Wijesundara 《Horticultural Plant Journal》 SCIE CAS CSCD 2022年第1期53-67,共15页
Syzygium cumini(L.)Skeels(Madan)is widely distributed in South Asian countries,including Sri Lanka,where it was naturally found.There were only few studies reported on S.cumini for its values and other benefits in Sri... Syzygium cumini(L.)Skeels(Madan)is widely distributed in South Asian countries,including Sri Lanka,where it was naturally found.There were only few studies reported on S.cumini for its values and other benefits in Sri Lanka.This study focuses on morphological characterization and the diversity of S.cumini trees in seven locations of Sri Lanka.Data were collected on different morphological traits.Leaf,flower and fruit morphology showed significant differences among locations.Further,trees from Batticaloa region showed different morphology,which would potentially open a different avenue for further study to trace different cultivars across the country.Results of the diversity index and multivariate analyses indicated high diversity in morphology and antioxidant capacity of trees.The variables such as leaf area,inter-nodal length,petiole length,anther length,filament length,fruit size and pericarp thickness could be suitable candidates to investigate the morphological variation of S.cumini any further.Antioxidant capacity studies also showed significant differences among locations and trees.Fruit hue angle was positively correlated to antioxidant capacities.Finding of this study concluded that the wide distribution of S.cumini trees throughout Sri Lanka in different geographical locations showed high diversity in leaf,flower and fruit morphology together with antioxidant capacity. 展开更多
关键词 Syzygium cumini Morphological diversity Antioxidant capacity Sri Lanka
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赤霉素和氨基酸对三叶赤楠(Syzygium grijsii)枝叶生长影响研究 认领 引用 被引量：4
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作者 刘玮 谢冰 +1 位作者 倪国平 邓光华 《植物研究》 CAS CSCD 北大核心 2011年第2期218-226,共9页
采用正交设计,研究了不同浓度氨基酸和赤霉素混合喷施对三叶赤楠枝条、叶片生长的影响。结果表明:三叶赤楠的生长曲线呈现双峰状,春秋季各有一生长高峰。氨基酸和赤霉素两者间交互作用显著,对三叶赤楠枝条和叶片生长均有一定的促进作用... 采用正交设计,研究了不同浓度氨基酸和赤霉素混合喷施对三叶赤楠枝条、叶片生长的影响。结果表明:三叶赤楠的生长曲线呈现双峰状,春秋季各有一生长高峰。氨基酸和赤霉素两者间交互作用显著,对三叶赤楠枝条和叶片生长均有一定的促进作用。但氨基酸对于三叶赤楠生长的促进作用有限,在观察到的生长差异中,绝大部分是由赤霉素浓度差异造成的。对于枝条及叶片生长来说,100 mg.L-1的赤霉素浓度比较合适。新梢长、新梢分枝数及叶面积受混合喷施影响较大,不同处理间差异显著或极显著,而成熟枝条及叶片厚度受其影响较小,差异不显著。经主成分分析发现新梢月平均生长量和分枝数可作为快速评价混合喷施效果的描述指标;而叶片厚度和叶面积,即第二主成分可作为潜在评价氨基酸和赤霉素混合喷施长期效果的描述指标。在生产中可以以新梢长度、生长量和分枝数作为评价氨基酸与赤霉素喷施效果的快速指标。 展开更多
关键词 三叶赤楠 氨基酸 赤霉素 枝叶生长
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Ameliorative Effects of Syzygium aromaticumEssential Oil on Fertility in Male Rats Exposed to Manganese 认领 引用 被引量：3
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作者 Farouk Boudou Abdelkrim Berroukche +3 位作者 Malika Bendahmane-Salmi Badreddine Abdelkrim Kandouci Djallel Edinne Houari adli Nasreddine Tou 《Advances in Sexual Medicine》 2013年第4期85-91,共7页
Introduction: Several substances were likely to cause the decline in male fertility which could go up to the complete sterility. The aim of this study was to assess the effects of Syzygium aromaticum essential oil on ... Introduction: Several substances were likely to cause the decline in male fertility which could go up to the complete sterility. The aim of this study was to assess the effects of Syzygium aromaticum essential oil on fertility in male rats exposed to manganese. Materials and Methods: Twenty four male rats, 6 months old, were divided into 2 groups;12 rats in one group received, by oral route, a water containing manganese chloride tetrahydrate (MnCl2·4H2O) is at the dose of 4.79 mg·ml-1 for 12 weeks. The group of control male rats received a distilled water in the same conditions. After a period of experimentation, each group was divided into two subgroups of 6 rats which received daily, by intraperitoneal way, a 0.1 mg/kg body weight, of Syzygium aromaticum essential oil. Results: After a chronic exposure, microscopic examination of the testes showed degeneration of the seminiferous tubules and the gremlin cell. Seminal parameters indicated a decrease in the sperm levels (21.3 × 106 cells/ml) and a rise of morphological abnormalities (66.1%). However, intraperitoneal administration of essential oil extracted from the flower buds of Syzygium aromaticum, during 3 weeks, to the rats previously intoxicated with Mn, showed a significant rising of sperm concentration (61.2 × 106 cells/ml) and a reduction of morphological abnormalities (10.8%). These changes were associated with a significant regeneration of seminiferous tubules and interstitial cells. Conclusion: This study revealed an ameliorative effect of essential oil Syzygium aromaticum in testicular tissue and the sperm quality. 展开更多
关键词 Fertility Sterility Manganese Essential Oil Syzygium aromaticum
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GC-MS Analysis of Clove Essential Oil (Syzygium aromaticum L.) as Effective Source of Biomolecules for Traditional Tomato Puree Quality Improvement 认领 引用 被引量：1
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作者 Oscar C. A. Akotowanou Euloge Sènan Adjou +7 位作者 Kowiou Aboudou Adéyèmi Berane Olubi Phillipe Sessou Franck Michels Akadiri Yessoufou Marie-Laure Fauconnier Lamine Baba-Moussa Dominique C. K. Sohounhloué 《Advances in Molecular Imaging》 CAS 2024年第4期39-49,共11页
The high-water content of tomato predisposes it to spoilage by microorganisms and led producers to carry out traditional processing of tomatoes in the form of pasteurized tomato puree. However, rapid acidification of ... The high-water content of tomato predisposes it to spoilage by microorganisms and led producers to carry out traditional processing of tomatoes in the form of pasteurized tomato puree. However, rapid acidification of these traditional tomato purees is often observed. Then, the aim of this study was to evaluate the efficacy of the essential oil extracted from Clove (Syzygium aromaticum L.) in the improvement of traditional tomato puree producing technology. Essential oil of Clove (Syzygium aromaticum L.) was extracted by hydrodistillation and its chemical composition was determined by GC and GC/MS. Different types of traditional tomato puree were produced by the modification of the traditional processing technology and the addition of the essential oil introduction step, followed by manual stirring during the process. Based on previous studies, two different essential oil concentrations (5.0 and 7.5 μL∙g−1) were investigated. Physicochemical, microbiological and nutritional analyzes were performed in order to evaluate the quality of the traditional tomato puree produced. Results obtained revealed that the essential oil of Syzygium aromaticum investigated has a chemical composition characterized by the presence of eugenol (59.11%) and eugenol acetate (33.73%). Good stabilization of the physicochemical, microbiological and nutritional parameters in traditional tomato puree samples preserved with essential oil of Syzygium aromaticum were observed when compared to control. The essential oil of Clove, with his biological property, offers a novel approach to the management of traditional tomato puree during storage. 展开更多
关键词 Essential Oil Syzygium aromaticum Tomato Puree Process Quality Benin
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Chemical constituents of Hainan Syzygium myrsinifolium(Hance)Merr.et Perry based on ultra-high performance liquid chromatography-time-of-flight tandem mass spectrometry 认领 引用 被引量：1
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作者 Chaohai Pang Yuan Xu +4 位作者 Xionghui Ma Yuwei Wu Shuhuai Li Pingping Li Zhenshan Zhang 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2022年第7期507-516,共10页
Syzygium myrsinifolium(Hance)Merr.et Perry is a unique plant resource on Hainan Island,and there are few reports on its chemical constituents.In the present study,we identified the major chemical constituents in the l... Syzygium myrsinifolium(Hance)Merr.et Perry is a unique plant resource on Hainan Island,and there are few reports on its chemical constituents.In the present study,we identified the major chemical constituents in the leaves of Syzygium myrsinifolium(Hance)Merr.et Perry using ultra-high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry(UPLC-Q-TOF-MS/MS).The chemical constituents in Syzygium myrsinifolium(Hance)Merr.et Perry were identified rapidly based on the accurate relative molecular mass and combined with literature data and reference substances.A total of 20 compounds,including organic acids,phenolic acids,and flavonoids,were identified.Among these 20 compounds,four organic acids,eight phenolic acids,seven flavonoids,and one coumarin were reported from the leaves of Syzygium myrsinifolium(Hance)Merr.et Perry for the first time.The established method was rapid and accurate,and some chemical constituents in the leaves of Syzygium myrsinifolium(Hance)Merr.et Perry have been identified.This research provided an experimental reference for the study of the constituents and utilization of Syzygium myrsinifolium(Hance)Merr.et Perry. 展开更多
关键词 Syzygium myrsinifolium(Hance)Merr.et Perry UPLC-Q-TOF-MS/MS Identification
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The Effect of Mixture of Alpinia Galanga, Eurycoma Longifolia Jack and Syzygium Aromaticum Crude Extract on the Growth of Saccharomyces Cerevisiae and Escherichia Coli 认领 引用 被引量：1
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作者 Nur Jasrina Jaafar Kaswandi Md. Ambia +1 位作者 Hing Hiang Lian Rahim Md. Noah 《Journal of Life Sciences》 2014年第5期399-403,共5页
Alpinia galanga, Eurycoma longifolia Jack and Syzygium aromaticum have been widely used in traditional medicine for decades. Antimicrobial activities for individual crude extract were well established. Crude methanoli... Alpinia galanga, Eurycoma longifolia Jack and Syzygium aromaticum have been widely used in traditional medicine for decades. Antimicrobial activities for individual crude extract were well established. Crude methanolic extracts of Alpinia galanga, Eurycoma longifolia Jack and Syzygium aromaticum and the combination for all extracts were tested using well diffusion techniques against Saccharomyces cerevisiae （ATCC 9763） and Escherichia coli （ATCC 25922）. The mixed extracts were prepared based on the concentration ratio of 50 μg/μL which are 1：1, 1：1：1 and 1：2：2. Single Syzygium aromaticum extract showed higher inhibition zone on Saccharomyces cerevisiae compared to Escherichia coli. There is reduction in diameter of inhibition zone for single extract and mixture extracts either in combination of two or three extracts tested on Saccharomyces cerevisiae and Escherichia coli growth but they are not significant. In conclusion, Syzygium aromaticum showed highest activity against Saccharomyces cerevisiae and Escherichia coli. Reduction in diameter of inhibition zone indicated that Alpinia galanga and Eurycoma longifolia Jack extracts had antagonistic effect with Syzygium aromaticum. 展开更多
关键词 Antifungal antibacterial extract Alpinia galanga Eurycoma longifolia Syzygium aromaticum Saccharomyces cerevisiae and Esherichia coli.
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Anti-Diabetic Activity of an Extract of Syzygium Jambolanum - A Review 认领 引用
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作者 Kirubanandan Shanmugam 《Journal of Clinical and Nursing Research》 2024年第3期220-231,共12页
Syzygium jambolanum is a promising natural treatment for diabetes.The potential benefits of S jambolanum for diabetes include lowering blood sugar levels,increasing insulin sensitivity,protecting pancreatic beta cells... Syzygium jambolanum is a promising natural treatment for diabetes.The potential benefits of S jambolanum for diabetes include lowering blood sugar levels,increasing insulin sensitivity,protecting pancreatic beta cells,and slowing the absorption of glucose into the bloodstream.The anti-diabetic activity of the crude extract of S jambolanum was evaluated in L6 myotubes and the lipid deposition in tissue was measured using Nile red Staining.Nile red staining confirmed that a considerable quantity of lipids had been deposited in the tissue treated with a crude extract of S jambolanum,comparable to the quantity of lipids deposited with a standard drug known as Rosiglitazone.This study analyzed the anti-diabetic activity of a crude extract of S jambolanum to understand its potential as a feedstock for extracting bioactive constituents to screen for bioactive molecules in the treatment of diabetes. 展开更多
关键词 Syzygium jambolanum L6 myoblasts Column chromatography Nile red staining
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Biological Activity of Syzygium aromaticumand Ravensara aromaticaEssential Oils from Madagascar and Their Possible Use against Postharvest Mango Anthracnose 认领 引用
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作者 Soloniony Navalonamanitra Andrianjafinandrasana Marc Chillet +3 位作者 Isabelle Ratsimiala Ramonta Jean-Michel Leong Pock Tsy Jerôme Minier Pascal Danthu 《American Journal of Plant Sciences》 CAS 2020年第11期1682-1697,共16页
The fungitoxicity of five Malagasy essential oils (Eos) against Colletotrichum asianum was assessed in terms of conidial germination and mycelial growth. Their effect on defense-related compounds content, physicochemi... The fungitoxicity of five Malagasy essential oils (Eos) against Colletotrichum asianum was assessed in terms of conidial germination and mycelial growth. Their effect on defense-related compounds content, physicochemical properties and anthracnose lesions in mango fruits was also determined. Four of the tested Eos were from Ravensara aromatica leaves, and the last Eo was extracted from clove leaves. Their chemical compositions were then determined through GC-MS analysis and the active compound of the most fungitoxic Eo was determined by testing the toxicity of its major component to C. asianums spore germination, mycelial growth and its ability to inhibit anthracnose development on mango fruits. The R. aromatica Eos tested were fungistatic to C. asianum, whereas clove Eo was fungitoxic and the 4 chemotypes of R. aromatica Eo exhibited variable inhibiting capabilities: 1) all tested doses of all Eos (112.5 and 225 μL/L of air) were effective against C. asianum mycelial growth (10% - 100% inhibition) but doses of 225 μL/L were more inhibitory than those of 112.5 μL/L, 2) Conidial germination was more resistant to Eos toxicity since only 225 μL/L of methyl eugenol chemotype of R. aromatica Eo, all tested doses of the sabinene chemotype of R. aromatica Eo and clove Eo were found inhibitory toward conidial germination of C. asianum. 30 μL/L of sprayed clove Eoweretested on inoculated mangoes and were found to be effective against anthracnose development without affecting the resorcinol content in mango peel and the physicochemical properties of mango pulp. Tests on the major components of clove Eo showed fungitoxic activities against mycelial growth and conidial germination of C. asianum similar to those of clove Eo. 展开更多
关键词 Biological Activity Syzygium aromaticum Ravensara aromatic Fungitoxicity Anthracnose Essential Oils
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Safety Assessment and Potential Anti-Inflammatory Effect of Ethanolic Extract of Syzygium aromaticumin Albino Rats 认领 引用
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作者 Twadu A. Saeed Osman A. Osman +1 位作者 Ahmed E. Amin Samia M. A. El Badwi 《Advances in Bioscience and Biotechnology》 CAS 2017年第11期411-420,共10页
The present study was undertaken to investigate the effect of the ethanolic extract of Syzygium aromaticum to albino rats. Forty eight Albino rats were employed to test the safety and the anti-inflammatory effect of t... The present study was undertaken to investigate the effect of the ethanolic extract of Syzygium aromaticum to albino rats. Forty eight Albino rats were employed to test the safety and the anti-inflammatory effect of the extract. Safety of the extract was examined on experimental animal’s model at three dose levels of the extract orally in daily doses for three weeks. Effects of S. aromaticum on rats revealed no significant effect on biochemical or haematological parameters. The anti-inflammatory effect of the extract was tested in four equal groups;groups 1 and 2 were treated with 250 and 500 mg/kg of the extract, respectively, group 3 was treated with indomethacine and group 4 was the untreated control. Carrageenan was used as an acute form inducer of inflammation. Indomethacine, the non-steroidal anti-inflammatory drugs (NSAIDs), was used as a reference compound. Oedema size was monitored at the 1st, 2nd, 4th, 6th and after 24 hours. The ethanolic extract of S. aromaticum showed significant (P 0.001) decreased in the oedema size at efficacy rates of 79.41%, 82.39% and 63.92% for the dose, 500 mg/kg body weight at the 2nd, 4th and 6th hour respectively higher than that produced by indomethacine. 展开更多
关键词 Syzygium aromaticum Ethanolic Extract Safety Anti-Inflammatory Rats
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Potential of Syzygium aromaticum(Clove) Leaf Extract on Immune Proliferation Response in Balb/c Mice Infected with Salmonella typhimurium 认领 引用
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作者 Syahran Wael Theopilus Wilhelmus Watuguly +8 位作者 Ine Arini Alwi Smit Nur Matdoan Dwi Retna Prihati Ana Bina Sari Didik Wahyudi Tri Rini Nuringtyas Nastiti Wijayanti Pudji Astuti 《Case Reports in Clinical Medicine》 2018年第12期613-627,共15页
Background and Objective: Syzygium aromaticum is an immunomodulator with the main active compound eugenol which can stimulate the function of lymphocyte proliferation and macrophage production. Lymphocytes play an imp... Background and Objective: Syzygium aromaticum is an immunomodulator with the main active compound eugenol which can stimulate the function of lymphocyte proliferation and macrophage production. Lymphocytes play an important role for body protection against infection. This study aims to analyze the effect of S. aromaticum extract to increase proliferation of lymphocytes, lymphoblasts and macrophage production in Balb/c mice infected with Salmonella typhimurium. Methodology: Mice strain Balb/c were divided into 4 groups: treatment group infected with S. typhimurium and control group (without treatment) to tested the activity of peritoneal macrophages. The treatment group was administrated by S. aromaticum leaf extract (15 mg, 75 mg, 150 mg/kgbw) for 12 days. Results: S. aromaticum leaf extract increased the proliferation activity (p Conclusion: Administration of S. aromaticum leaf extract increased the proliferation activity of lymphocytes, lymphoblasts and ROI secretion of macrophagesin Balb/c mice infected with S. typhimurium. 展开更多
关键词 Syzygium aromaticum Lymphocytes Lymphoblast Macrophage Salmonella typhimurium
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Syzygium aromaticum L.(Clove):A Comprehensive Review of Its Ethnopharmacological Uses and Pharmacological Activities 认领 引用
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作者 Tae-Young Gil Sung-Jin Kim Hyo-Jin An 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2026年第2期165-173,共9页
Herbal remedies play important roles in promoting health and treating various ailments.(1) Recently,medicinal plants have been increasingly used for various applications due to their historical use,accessibility,an... Herbal remedies play important roles in promoting health and treating various ailments.(1) Recently,medicinal plants have been increasingly used for various applications due to their historical use,accessibility,and perceived safety.(2) Herbal medicines'accessibility and versatility have led to their growing application as medications and functional dietary supplements. 展开更多
关键词 clove promoting health pharmacological activities syzygium aromaticum l ethnopharmacological uses functional dietary supplements herbal medicinesaccessibility treating various ailments
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Miocene Syzygium Gaertn.(Myrtaceae)from India and its ancestral lineages from Gondwanaland 认领 引用
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作者 Sadanand Harshita Bhatia +2 位作者 Purushottam Adhikari Rashmi Srivastava Gaurav Srivastava 《Journal of Palaeogeography》 SCIE CSCD 2026年第2期274-286,共13页
Syzygium is the largest woody angiosperm genus,widely distributed across tropical and subtropical regions in the Old World.Despite its ecological prominence,its fossil record remains underexplored,leading to ongoing d... Syzygium is the largest woody angiosperm genus,widely distributed across tropical and subtropical regions in the Old World.Despite its ecological prominence,its fossil record remains underexplored,leading to ongoing debates about its origin and biogeographic history.This study reports eleven newly discovered Syzygium fossil leaves from the Early Miocene Kasauli Formation of Himachal Pradesh,India.Based on morphological and cluster analysis of 156 plant species across 21 extant angiosperm families,utilizing 22 leaf morphological characters with 79 different character states,we identified the fossil as a new species,Syzygium paleosalicifolium sp.nov.Additionally,we reinvestigated previously reported Syzygium fossils from the Paleogene and Neogene sediments of India to refine evolutionary timeline of the genus.Our findings confirmed the presence of Syzygium in India since at least the early Eocene,challenging hypotheses of an exclusively Australian or Southeast Asian origin.The Indian fossil record supports an East Gondwanan lineage,predating the proposed Miocene origin and diversification of the genus.Furthermore,our results suggest that Syzygium may have diversified earlier than the~51.2 Ma crown age estimated by molecular phylogenetic studies. 展开更多
关键词 Leaf flora Pre-Siwalik Biogeography Cluster analysis South Asia Syzygium fossil
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