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The biochemical and metabolic adaptations underpinning the health benefits of exercise 认领 引用
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作者 Robyn M.Murphy Mark A.Febbraio 《Journal of Sport and Health Science》 SCIE CAS CSCD 2026年第1期1-2,共2页
1.Introduction The field of exercise science is experiencing a renaissance,with recent research illuminating the molecular,cellular,and systemic effects of physical activity.This is largely due to the now unequivocal ... 1.Introduction The field of exercise science is experiencing a renaissance,with recent research illuminating the molecular,cellular,and systemic effects of physical activity.This is largely due to the now unequivocal evidence that a lack of physical activity,not only has direct effects on the prevalence of non-contagious diseases(NCDs)but has profound additive effects of other risk factors for NCD such as obesity and hypertension.1 The articles in this special topic of Journal of Sport and Health Science(JSHS)are dedicated to research on Exercise biochemistry&metabolism. 展开更多
关键词 obesity metabolic adaptations exercise health benefits exercise science biochemical adaptations physical activity non contagious diseases
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Speciation,endangerment and adaptation in limestone rocky environment of Urophysa(Ranunculaceae) 认领 引用 被引量：2
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作者 Deng-Feng Xie Yi-Yang Zhang +6 位作者 Jing Cai Rui-Yu Cheng Yuan Wang Jin-Bo Tan Yan Yu Xing-Jin He Song-Dong Zhou 《Plant Diversity》 SCIE CAS CSCD 2026年第2期231-245,共15页
Urophysa(Ranunculaceae)are plants endemic to the limestone regions of southern China,representing an attractive model for studying species differentiation,endangerment,and adaptive evolution in karst environments.Here... Urophysa(Ranunculaceae)are plants endemic to the limestone regions of southern China,representing an attractive model for studying species differentiation,endangerment,and adaptive evolution in karst environments.Here,we assembled a chromosome-level genome of U.rockii,and re-sequenced 97 individuals of two Urophysa species.The final genome size was 303.21 Mb with a heterozygosity level of approximately 0.26%.Demographic analyses revealed that U.rockii diverged from U.henryi around 5.95million years ago,dramatic orogenies and climatic shifts in the Hengduan Mountain(HDM)during the Late Miocene to Pleistocene enhanced population divergence and accelerated allopatric speciation.Extremely low genetic diversity was detected in U.rockii,particularly in the populations CXS and PZ(8.7×10-5 and 9.6×10-5).Long-term bottleneck effects,limited gene flow,habitat specialization and severe inbreeding collectively contributed to its endangerment status.Genomic scan(top 5%FSTandπratio)of Urophysa species identified 257 selected genes linked to karst adaptation.Complementary physiological experiments and transcriptome analyses further detected multiple candidate genes under positive selection and expansion(e.g.,TPC1,PTR/POT,and CAX3).Maintaining cell wall integrity,regulating ion absorption and excretion,and sequestering excess ions into organelles(e.g.,vacuole and mitochondrion)are key survival strategies for Urophysa species in harsh limestone rocky environments.Our findings elucidate the evolutionary patterns and mechanisms underlying species adaptation to karst ecosystems,and identify key drivers of endangerment within such ecologically specialized habitats. 展开更多
关键词 Urophysa Demographic history Species divergence Endangerment Karst adaptation
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GcH1 contributes to high-altitude adaptation in Tibetans by regulating blood nitric oxide 认领 引用 被引量：2
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作者 Yongbo Guo Wangshan Zheng +6 位作者 Tian Yue Baimakangzhuo Xuebin Qi Kai Liu Liya Li Yaoxi He Bing Su 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2026年第1期97-109,共13页
Nitric oxide(NO)is a key vasodilator that regulates vascular pressure and blood flow.Tibetans have developed a"blunted"mechanism for regulating NO levels at high altitude,with GTP cyclohydrolase 1(GCH1)ident... Nitric oxide(NO)is a key vasodilator that regulates vascular pressure and blood flow.Tibetans have developed a"blunted"mechanism for regulating NO levels at high altitude,with GTP cyclohydrolase 1(GCH1)identified as a key candidate gene.Here,we present comprehensive genetic and functional analyses of GCH1,which exhibits strong Darwinian positive selection in Tibetans.We show that Tibetan-enriched GCH1 variants down-regulate its expression in the blood of Tibetans.Based on this observation,we generate the heterozygous Gch1 knockout(Gch1+/-)mouse model to simulate its downregulation in Tibetans.We find that under prolonged hypoxia,the Gch1+/-mice have relatively higher blood NO and blood oxygen saturation levels compared with the wild-type(WT)controls,providing better oxygen supplies to the cardiovascular and pulmonary systems.Markedly,hypoxia-induced cardiac hypertrophy and pulmonary remodeling are significantly attenuated in the Gch1^(+/-)mice compared with the WT controls,likely due to the adaptive changes in molecular regulations related to metabolism,inflammation,circadian rhythm,extracellular matrix,and oxidative stress.This study sheds light on the role of GCH1 in regulating blood NO,contributing to the physiological adaptation of the cardiovascular and pulmonary systems in Tibetans at high altitude. 展开更多
关键词 GCH1 Nitric oxide Tibetans High altitude Hypoxia Adaptation
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Metabolic adaptations of Qingke:A review of stress resilience and nutritional functions 认领 引用 被引量：2
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作者 Congping Xu Yulin Wang +19 位作者 Naoxue Fei Yuzhen Basang Haizhen Yang Jiabu Dunzhu Hongjun Yuan Mu Wang Sang Zha Wa Da Taba Xiongnu Puci Basang Chunbao Yang Qijun Xu Zexiu Wei Yawen Gan Yawei Tang Alisdair R.Fernie Zhaoyan Chen Jie Luo Ganggang Guo Xingquan Zeng 《The Crop Journal》 SCIE CSCD 2026年第1期61-73,共13页
Qingke,a staple crop grown on the high-altitude Tibetan Plateau,has evolved a metabolomic profile providing both environmental stress resilience and human nutrition.We review the hypothesis that the metabolites that c... Qingke,a staple crop grown on the high-altitude Tibetan Plateau,has evolved a metabolomic profile providing both environmental stress resilience and human nutrition.We review the hypothesis that the metabolites that confer cold and UV resistance on the crop also facilitate human adaptation to high-altitude stresses.Specifically,β-glucans regulate blood glucose primarily via short-chain fatty acids(SCFAs)produced through gut microbiota fermentation,which directly mediate glucose homeostasis.Phenolamides accumulate via the phenylpropanoid pathway,with chalcone isomerase(CHI)serving as a key enzyme in flavonoid biosynthesis and enhancing UV-B resistance.Under low temperatures,β-glucans improve frost tolerance by modulating osmotic balance and inhibiting ice-nucleating proteins,while lipids maintain membrane fluidity to sustain cellular function during cold stress.Importantly,we explore the hypothesis that these same metabolites,upon consumption,may facilitate human adaptation to high-altitude stresses.This hypothesis is supported by preliminary epidemiological associations between Qingke consumption and favorable health outcomes in high-altitude populations,as well as established bioactivities of the implicated metabolites in vitro and in animal models.However,direct causal evidence in humans and a comprehensive understanding of the underlying molecular mechanisms remain key knowledge gaps that warrant future investigation.Qingke as a unique resource at the interface of agricultural resilience and human nutrition.Understanding its metabolic blueprint will inform the development of functional foods and climate-resilient crops. 展开更多
关键词 Qingke Metabolomics Multi-omics integration Plateau adaptation
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Chromosome-level genome assembly and population genomics analysis of Camellia rubituberculata provide insights into adaptation to karst habitats 认领 引用 被引量：2
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作者 Chao Yan Ming-tai An +4 位作者 Ming Tang Xin-xiang Bai Xu Xiao Zhao-hui Ran Zhi Li 《Plant Diversity》 SCIE CAS CSCD 2026年第2期246-261,共16页
Karst flora confined to isolated‘habitat islands'evolve specialized adaptations and unique traits,serving as ideal models for investigating adaptive evolution and species diversification mechanisms.Camellia rubit... Karst flora confined to isolated‘habitat islands'evolve specialized adaptations and unique traits,serving as ideal models for investigating adaptive evolution and species diversification mechanisms.Camellia rubituberculata,endemic to the karst habitats of Guizhou,China,can serve as a model for adaptive evolution and diversity in karst-endemic woody species.However,the lack of a chromosome-level genome for this species has limited in-depth studies on its adaptations to karst and posed a barrier to its genetic improvement.In this study,a chromosome-level genome assembly of C.rubituberculata was generated,with 15 pseudo-chromosomes and a genome size of 2.50 Gb(scaffold N50=168.34 Mb,55,302 protein-coding genes).Comparative genomics revealed two whole-genome duplications(WGDs),namely,an ancient γ-event(~120 Mya)and a subsequent genus-wide event(~86 Mya),after which gene families linked to karst adaptation(e.g.,photosynthesis)were significantly expanded.Selective sweep analysis showed that selected genes were associated with phytohormone transmission and metabolism.Genes functionally annotated as involved in stress responses—including SAUR,BSK,NCL,CDPK,and NDPK—participate in calcium homeostasis and ion transport pathways under karstspecific stresses.MYB transcription factors,which are crucial in plant responses to stresses,including drought,may be key for adaptation to the high salinity and drought stress in karst environments.The divergent selection in wild and cultivated groups highlight key adaptations in plant hormone transduction and calcium transport.By elucidating karst adaptation in C.rubituberculata,this work establishes essential genomic resources for advancing genetic evolution research and molecular breeding across Camellia species. 展开更多
关键词 Camellia rubituberculata Endemic species Genome assembly Karst adaptation Population genetics
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Genomic insights into alpine plant adaptation 认领 引用 被引量：1
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作者 Xu Zhang Tao Deng +1 位作者 Hengchang Wang Hang Sun 《Plant Diversity》 SCIE CAS CSCD 2026年第3期439-450,共12页
Alpine plants persist in some of the harshest terrestrial environments,where low temperatures,high ultraviolet radiation,and short growing seasons impose strong selective pressures.Recent advances in genome sequencing... Alpine plants persist in some of the harshest terrestrial environments,where low temperatures,high ultraviolet radiation,and short growing seasons impose strong selective pressures.Recent advances in genome sequencing and comparative genomics are unraveling the multifaceted mechanisms that enable their adaptation and diversification under these conditions.In this review,we synthesize current progress on how genetic variation at different levels,including single nucleotide polymorphisms(SNPs),structural variants,whole-genome duplication,gene family evolution,and transposable elements,contribute to high-elevation adaptations in alpine plants.SNP-based studies have provided critical insights into adaptive differentiation along environmental gradients as well as molecular convergence underlying high-elevation adaptation,while analyses of structural variations and transposable elements reveal their potential roles in shaping phenotypic diversity and environmental responsiveness.Despite these advances,major challenges remain in linking genomic variation to functional adaptation,reflecting limitations in sampling,comparative frameworks,and functional validation.This review emphasizes the promise of integrative multiomics,pangenome reconstruction,and functional assays to bridge these gaps,and highlights how genomic insights can guide the conservation of alpine biodiversity under accelerating climate change. 展开更多
关键词 Alpine adaptation Multi-omics Structural variants Transposable elements Whole-genome duplication
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Evaluating farmers' strategies and socioeconomic drivers for adaptation to climate uncertainty: A case study in the Himalayan region of West Bengal,India 认领 引用
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作者 Sourakanti SARKAR Aishi MUKHERJEE +6 位作者 Auindrila BISWAS Subrata GORAIN Bimal BERA Anmol GIRI Malini ROY CHOUDHURY Suman DUTTA Sumanta DAS 《Regional Sustainability》 CAS CSCD 2026年第2期116-137,共22页
Climate change poses a profound threat to mountain agro-ecosystems,particularly in the Himalayan region of West Bengal,India,by disrupting precipitation patterns,increasing temperature variability,and intensifying ext... Climate change poses a profound threat to mountain agro-ecosystems,particularly in the Himalayan region of West Bengal,India,by disrupting precipitation patterns,increasing temperature variability,and intensifying extreme weather events.Despite growing evidence of climate change impacts,there remains a critical research gap in understanding how socioeconomic factors drive farmers' adaptation strategies to climate change in this vulnerable region.This study examines how farmers in the Himalayan region of West Bengal,India,perceived and responded to the growing impacts of climate change on mountain agro-ecosystems.Drawing on cross-sectional data from 370 farm households selected through multistage sampling,the research employs a combination of analytical tools,including the severity index(SI) to assess farmers' perceptions to climate change,the adaptation index(AI) to evaluate adaptive responses,the Garrett's ranking technique to prioritize constraints,and the ordered logistic regression to identify key socioeconomic drivers of adaptation.Findings reveal a high level of climate awareness among farmers,particularly regarding the increase in weather extremes(SI=74.87%),increase in temperature(SI=72.31%),and irregular rainfall patterns and highly erratic rainfall(SI=62.52%).The most commonly adopted strategies include adopting intercropping and mixed cropping systems(AI=0.613),adoption of the integrated farming system model(AI=0.600),and shift towards non-farm employment(AI=0.608),while the adoption of climate-resilient crop varieties and improved irrigation remains limited.Regression analysis highlights that education(regression coefficient=0.38),average landholding size(regression coefficient=1.21),and access to daily weather forecast information(regression coefficient=1.92) significantly promote adaptive behaviour,whereas age(regression coefficient= –0.09) and gender(regression coefficient= –0.76) are negatively associated.Institutional constraints,particularly unavailability of institutional credit,emerge as primary barriers.The study underscores the urgent need for region-specific,inclusive policy frameworks that enhance climate advisory services,support technology dissemination,and empower marginalized groups in the Himalayan region of West Bengal.By fostering informed,equitable,and resilient agricultural systems,these strategies can significantly strengthen the adaptive capacity of mountain farming communities and contribute to sustainable development under a changing climate. 展开更多
关键词 Adaptation index Severity index Climate change Adaptation strategies Garrett's ranking Himalayan region
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Adaptation needs and adaptation options vary among different stakeholders in high-latitude protected areas: A case study of the Qiangtang Protected Area in China 认领 引用
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作者 Jianguo Wu Mengdi Fu 《Chinese Journal of Population,Resources and Environment》 CSCD 2026年第1期110-128,共19页
It is essential to understand how adaptation needs and options differ among stakeholders in protected areas(PAs)to effectively implement climate change(CC)adaptation strategies.Using the Qiangtang PA in Xizang as a ca... It is essential to understand how adaptation needs and options differ among stakeholders in protected areas(PAs)to effectively implement climate change(CC)adaptation strategies.Using the Qiangtang PA in Xizang as a case study,this research examines CC adaptation needs and options from the perspectives of stakeholders across multiple administrative levels,including provincial,prefectural,county authorities,73 protection stations,and 13364 pastoralists residing within the PA.The findings show that stakeholders at the provincial level,as well as those from the Ali and Naqu prefectures and six counties,place greater emphasis on institutional and resource-related needs than on other categories(attention score:7.0-9.3 vs.5.0-7.0).In contrast,stakeholders from the 73 protection stations prioritize technological and capacity-building needs more strongly than other types(attention score:8.0-9.0 vs.4.0-8.0).The 13364 pastoralists assign the highest importance to social needs relative to other categories(attention score:9.0-9.5 vs.3.0-8.0).Most of the eight existing protection measures were found to indirectly support broader climate adaptation efforts.In particular,protective actions addressing fire,pests,and weather-related disasters can be classified as autonomous adaptation,while other measures generate outcomes that enhance adaptation capacity under specific conditions.Adaptation options,grouped into three main types and 13 subcategories,differ across stakeholder groups,although substantial overlap exists between these options and current protective actions,including ecosystem based adaptation strategies,adaptation-related practices,autonomous adaptation measures,and emergency interventions.Overall,these findings highlight the critical role of all stakeholders-especially staff from the 73 protection stations and the 13364 pastoralists-in the effective implementation of adaptation actions within the PA. 展开更多
关键词 Climate change Biodiversity conservation Protected area Adaptation needs Adaptation options
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Local adaptation sustains genetic differentiation between two varieties of Chinese walnut(Juglans cathayensis)despite extensive hybridization in subtropical China 认领 引用
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作者 Wan Hu Caixia Han +11 位作者 Li Li Chunhua Zang Runzi Li Hong Nie Jianbo Nie Yong Shi Chen Feng Jie Zhang Yixuan Kou Zhiyong Zhang Dengmei Fan Danqi Li 《Plant Diversity》 SCIE CAS CSCD 2026年第4期734-746,共13页
Understanding how natural selection sustains genetic differentiation despite ongoing hybridization remains a central question in evolutionary biology.Here,we integrated range-wide whole-genome resequencing data and ec... Understanding how natural selection sustains genetic differentiation despite ongoing hybridization remains a central question in evolutionary biology.Here,we integrated range-wide whole-genome resequencing data and ecological niche modeling to elucidate the evolutionary history,local adaptation,and hybridization patterns of Juglans cathayensis,a walnut species widely distributed across subtropical China.Our analyses revealed that Chinese walnut comprised two genetic clusters corresponding to its two recognized varieties,which were further subdivided into three lineages:the East lineage,consisting exclusively of J.cathayensis var.formosana individuals;and the West and Admixed lineages,comprising genetically pure and admixed individuals of J.cathayensis var.cathayensis,respectively.The admixed populations formed a hybrid zone in the ecotone between the East and West lineages.Divergence between the East and West lineages dates to the Middle Pliocene,with persistent bidirectional gene flowuntil the mid-Pleistocene,likely driven by long-term local adaptation to niche differences between eastern and western China.Genomic regions of differentiation may result from divergent selection under gene flowand divergent sorting of ancient polymorphisms.Moreover,we identifiedpositively selected genes and environment-associated loci involved in ecological adaptation,underscoring their role in promoting intraspecificdifferentiation.Bayesian genomic cline analysis detected limited introgression of adaptive loci in the hybrid zone,suggesting that natural selection sustains divergence in genomic regions associated with local adaptation,while neutral loci are homogenized through hybridization.Together,these findingsprovide novel insights into the evolutionary mechanisms shaping plant diversity in subtropical China,a region recognized as an evolutionary cradle. 展开更多
关键词 Local adaptation Genetic differentiation Hybrid zone Juglans cathayensis Subtropical China
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Understory functional trait adaptation to climate change is primarily mediated by soil conditions under long-term afforestation on the Loess Plateau 认领 引用
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作者 Huifeng Wu Zhao Jin +5 位作者 Jing Zhang Guofan Cao Mingkui Hao Yibo Liu Jun Pan Ji Liu 《Forest Ecosystems》 SCIE CAS CSCD 2026年第3期539-548,共10页
Soil and climate conditions drive plant trait variation in natural ecosystems.However,afforestation induces rapid and significant shifts in these environmental drivers.Yet the extent to which such abrupt shifts alter ... Soil and climate conditions drive plant trait variation in natural ecosystems.However,afforestation induces rapid and significant shifts in these environmental drivers.Yet the extent to which such abrupt shifts alter functional traits remains poorly understood.Here,we conducted a paired sub-watershed study in China's Loess Plateau,where over 70 years of afforestation and natural recovery have occurred.Functional traits of 59 her-baceous species were assessed.Combined with high-frequency microclimate monitoring and grid-based soil sampling,we used random forest and partial least squares path modeling(PLS-PM)to evaluate how afforestation-driven soil and microclimate influence trait variation.Afforestation significantly altered community-level functional traits of herbaceous plants,including morphological traits(plant height,specific leaf area(SLA)),chemical traits(leaf carbon to nitrogen ratio(C:N)),and tissue density traits(leaf and root dry matter content(LDMC and RDMC)).In contrast,individual-level responses were generally weak,with only the C:N ratio showing significant change.Compared with microclimate alterations,integrated changes in soil condi-tions,particularly soil water content(PLS-PM loading=0.828),emerged as the dominant drivers of community-level trait variation.In addition,microclimate effects were minor and often opposed soil-mediated responses.Overall,afforestation gradually reshapes the functional composition of herbaceous communities through species turnover and subtle intraspecific shifts,driven by persistent changes in habitat structure.Under ongoing climate change,the influence of afforestation on understory plant traits is predominantly mediated by soil processes.These findings suggest that climate-induced impacts on herbaceous communities may likewise be buffered through soil-driven pathways. 展开更多
关键词 Afforestation Understory adaptation Soil water Functional traits Loess plateau
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Form and load transfer aspects of foundation systems:Case-based implementation and adaptation for buildings 认领 引用
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作者 Abolfazl Eslami Amirhossein Ebrahimipour +2 位作者 Meysam Imani Reza Imam Pinqiang Mo 《Deep Underground Science and Engineering》 EI CAS CSCD 2026年第1期176-192,共17页
Conventionally,foundations have been classified as shallow or deep in routine civil engineering practice.However,due to recent developments,two other approaches,semi-deep and ground modification foundations,are now av... Conventionally,foundations have been classified as shallow or deep in routine civil engineering practice.However,due to recent developments,two other approaches,semi-deep and ground modification foundations,are now available,complicating foundation categorization.Accordingly,a new concept for foundation categorization is introduced in this paper based on insights into the theory of structure analysis.Based on the form aspect,foundation systems can be categorized as one-dimensional(linear),two-dimensional(planar),and threedimensional(volumetric).Based on the load transfer aspect,foundations can also be categorized as vector-acting(piles),section or surface-acting(rafts and shells),and block-acting(piled rafts).As a step toward implementing this new categorization scheme,a database of 22 cases has been compiled,symbolizing novel introduced foundation systems.This compilation involves structures such as offshore jackets,high-rise buildings,towers and storages,and diverse geomaterials.Among them,a few have been selected for detailed evaluation,emphasizing influential factors in foundation selection,comprising superstructure,subsoil condition,foundation system,circumferential conditions,and supplementary considerations,that is,constructional and sustainability-based issues.Lessons learned from experience and these knowledge-based cases have described for foundation selection and implementation.Geotechnical and practical aspects with critical components have been realized as major performance assessment and comparison factors.Foundation systems have been compared and ranked using the improved analytic hierarchy process approach.Finally,four categories of buildings,from low-rise to towers and four prevailing levels of soil strength,from soft to very hard,have been considered to propose a perspective for building substructure implementation,adapted via relevant cases.Overall,the introduced categorization is recognized as an efficient algorithm for the experimentation of appropriate foundations for specific structures and subsoil conditions. 展开更多
关键词 case-based adaptation form foundation system load transfer underground substructure
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Molecular divergence of TRPA1 in cetaceans supports lineage-specific adaptation to aquatic life 认领 引用
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作者 Tian-Zhen Wu Xian-Ting Huang +3 位作者 Yu-Qing Deng Luo-Ying Deme Shi-Xia Xu Guang Yang 《Zoological Research》 SCIE CSCD 2026年第1期117-127,共11页
Gene loss represents a powerful driver of adaptive evolution.Cetaceans,which underwent a profound transition from terrestrial to fully aquatic life,provide an excellent model for investigating this process.Comparative... Gene loss represents a powerful driver of adaptive evolution.Cetaceans,which underwent a profound transition from terrestrial to fully aquatic life,provide an excellent model for investigating this process.Comparative genomic analysis of the cold-sensitive ion channel transient receptor potential ankyrin 1(TRPA1)revealed lineage-specific patterns of degeneration across cetaceans.In toothed whales,the ancestral lineage exhibited extensive exon loss within the TRPA1 locus,whereas baleen whales showed signatures consistent with markedly reduced or absent TRPA1 expression.These molecular alterations were inferred to disrupt or abolish TRPA1 protein function across cetaceans.Integration of these findings with established experimental evidence from human and murine TRPA1 studies supported several adaptive hypotheses for TRPA1 gene loss,including tolerance to abrupt thermal fluctuations,attenuation of nociceptive responses in aquatic environments,specialization of integumentary sensory systems,and the emergence of echolocation-associated sensory trade-offs in toothed whales.Collectively,these findings expand the gene loss repertoire of cetaceans and provide novel insights into the molecular underpinnings of secondary aquatic adaptation in mammals. 展开更多
关键词 Cetacean Gene loss TRPA1 Molecular evolution Evolutionary adaptation
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Chromosome-level genome and population genomics reveal demographic history,incomplete divergence and coastal adaptation of Rhododendron simsii var.putuoense in East China 认领 引用
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作者 Hong Zhu Haojie Gao Hepeng Li 《Plant Diversity》 SCIE CAS CSCD 2026年第3期635-639,共5页
Geographical isolation plays a crucial role in species divergence and adaptive evolution(Worsham et al.,2017;Loretán et al.,2020).This phenomenon is especially pronounced in land-sea interactive habitats,where ge... Geographical isolation plays a crucial role in species divergence and adaptive evolution(Worsham et al.,2017;Loretán et al.,2020).This phenomenon is especially pronounced in land-sea interactive habitats,where geological shifts and climatic variations have significantly influenced genetic structures and distribution patterns by repeatedly modifying habitat connectivity(Jiang et al.,2021).Land-bridge islands,which extend from continental shelves and experience alternating phases of connection and isolation due to glacially driven sea-level fluctuations,function as natural laboratories for investigating species divergence,gene flow,and ecological adaptation(Jin et al.,2016;Cros et al.,2020).The Zhoushan Archipelago,China's largest archipelago,located on the northern margin of the subtropical zone,has undergone similar geological dynamics(repeated geological linkages and separations from the mainland),forming a distinct"island-continent disjunct distribution"pattern.This characteristic makes it an ideal system to study plant responses to geographical isolation in East Asia(Zhang et al.,2025). 展开更多
关键词 Rhododendron simsii var.putuoense de novo assembly Comparative genomics Population genomics Demographic history Coastal adaptation
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Emergence of a novel H4N6 avian influenza virus with mammalian adaptation isolated from migratory birds in Zhejiang Province,China,2024 认领 引用
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作者 Yongchun Yang Han Liu +3 位作者 Yaling Li Lin Liu Tiantian Chen Jiahao Zhang 《Virologica Sinica》 SCIE CAS CSCD 2026年第2期466-469,共4页
Dear Editor,Avian influenza viruses(AIVs)continue to evolve at the interface of wild and domestic birds,posing ongoing threats to animal and public health(Bi et al.,2020;Uyeki et al.,2022).Wild migratory birds serve a... Dear Editor,Avian influenza viruses(AIVs)continue to evolve at the interface of wild and domestic birds,posing ongoing threats to animal and public health(Bi et al.,2020;Uyeki et al.,2022).Wild migratory birds serve as natural reservoirs and facilitate viral gene exchange through long-distance migration,whereas dense poultry farming in East Asia creates opportunities for reassortment and spillover(Li P.et al.,2022;Verhagen et al.,2015).Historically,H4-subtype AIVs have been considered low-pathogenic,yet recent detections in poultry and swine suggest an expanding host range and genetic plasticity(Li et al.,2024;Song et al.,2024;Parsons et al.,2023). 展开更多
关键词 H N Zhejiang province mammalian adaptation influenza viruses aivs continue avian influenza viruses poultry farming China migratory birds
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Gearbox Fault Diagnosis under Varying Operating Conditions through Semi-Supervised Masked Contrastive Learning and Domain Adaptation 认领 引用
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作者 Zhixiang Huang Jun Li 《Computer Modeling in Engineering & Sciences》 SCIE EI 2026年第2期448-470,共23页
To address the issue of scarce labeled samples and operational condition variations that degrade the accuracy of fault diagnosis models in variable-condition gearbox fault diagnosis,this paper proposes a semi-supervis... To address the issue of scarce labeled samples and operational condition variations that degrade the accuracy of fault diagnosis models in variable-condition gearbox fault diagnosis,this paper proposes a semi-supervised masked contrastive learning and domain adaptation(SSMCL-DA)method for gearbox fault diagnosis under variable conditions.Initially,during the unsupervised pre-training phase,a dual signal augmentation strategy is devised,which simultaneously applies random masking in the time domain and random scaling in the frequency domain to unlabeled samples,thereby constructing more challenging positive sample pairs to guide the encoder in learning intrinsic features robust to condition variations.Subsequently,a ConvNeXt-Transformer hybrid architecture is employed,integrating the superior local detail modeling capacity of ConvNeXt with the robust global perception capability of Transformer to enhance feature extraction in complex scenarios.Thereafter,a contrastive learning model is constructed with the optimization objective of maximizing feature similarity across different masked instances of the same sample,enabling the extraction of consistent features from multiple masked perspectives and reducing reliance on labeled data.In the final supervised fine-tuning phase,a multi-scale attention mechanism is incorporated for feature rectification,and a domain adaptation module combining Local Maximum Mean Discrepancy(LMMD)with adversarial learning is proposed.This module embodies a dual mechanism:LMMD facilitates fine-grained class-conditional alignment,compelling features of identical fault classes to converge across varying conditions,while the domain discriminator utilizes adversarial training to guide the feature extractor toward learning domain-invariant features.Working in concert,they markedly diminish feature distribution discrepancies induced by changes in load,rotational speed,and other factors,thereby boosting the model’s adaptability to cross-condition scenarios.Experimental evaluations on the WT planetary gearbox dataset and the Case Western Reserve University(CWRU)bearing dataset demonstrate that the SSMCL-DA model effectively identifies multiple fault classes in gearboxes,with diagnostic performance substantially surpassing that of conventional methods.Under cross-condition scenarios,the model attains fault diagnosis accuracies of 99.21%for the WT planetary gearbox and 99.86%for the bearings,respectively.Furthermore,the model exhibits stable generalization capability in cross-device settings. 展开更多
关键词 Gearbox variable working conditions fault diagnosis semi-supervised masked contrastive learning domain adaptation
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Integrative role of CTPS cytoophidia in polyploid tissue growth and nutrient adaptation 认领 引用 被引量：1
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作者 Jiayi Hong Jiamin Li +4 位作者 Yuanbing Zhang Jing Wang Chengui Li Ji-Long Liu Jingnan Liu 《Insect Science》 SCIE CAS CSCD 2026年第4期1465-1480,共16页
Tissue growth and development are fundamental to organismal survival,requiring precise coordination of metabolic processes,nutrient availability,and signaling pathways.Cytidine triphosphate synthase(CTPS)is a rate-lim... Tissue growth and development are fundamental to organismal survival,requiring precise coordination of metabolic processes,nutrient availability,and signaling pathways.Cytidine triphosphate synthase(CTPS)is a rate-limiting enzyme in nucleotide biosynthesis and assembles filamentous cytoophidia,conserved across species.Despite increasing interest in cytoophidia,how CTPS filaments integrate metabolic and signaling cues to drive cell size and tissue growth remains incompletely understood.Using RNA interference and clustered regularly interspaces short palindromic repeats(CRISPR)/CRISPR-associate nuclease 9 gene editing,we generated CTPS-knockdown and pointmutated mutants to investigate the role of cytoophidia in cell growth.Specifically,we introduced the H355A mutation,which disrupts CTPS filament formation without affecting its enzymatic activity.Our findings revealed that CTPS depletion or filament disruption significantly impairs growth in polyploid organs,such as the fat body and salivary glands,underscoring the pivotal role of CTPS cytoophidia in cell growth regulation.Mutants lacking cytoophidia exhibited reduced DNA replication activity and smaller cell sizes compared to wild-type controls.Mechanistically,we found that nutrient-sensing pathways,particularly insulin-PI3K-Akt signaling pathway,regulate CTPS expression and cytoophidia formation in response to nutrient availability.Activation of the sterol regulatory elementbinding protein partially rescued the growth defects caused by CTPS depletion.These findings provide new insights into the molecular mechanisms of the regulation of CTPS filaments,highlighting their role as critical mediators of tissue growth by integrating environmental demands,metabolism,and signaling pathways to regulate cell size and nutrient adaptation. 展开更多
关键词 CTPS cell size cytoophidia DNA replication activity nutrient adaptation tissue growth
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Adaptation of microbial gene polymorphisms of the partial nitritation-anammox process for maintaining denitrification performance and robustness under salinity stress 认领 引用 被引量：1
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作者 Risen Yang Yanxiao Wei +7 位作者 Jianhong Jiang Xinying Kong Sha Wu Qingchang Tang Yangkai Liu Le Luo E.A.E.Ali Hong Chen 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第2期39-50,共12页
To explore the adaptive mechanisms of the partial nitritation-anammox(PNA)process under high salinity stress during kitchen wastewater treatment,focusing on their physiological and molecular responses through metageno... To explore the adaptive mechanisms of the partial nitritation-anammox(PNA)process under high salinity stress during kitchen wastewater treatment,focusing on their physiological and molecular responses through metagenomic analysis.An airlift inner-circulation partition bioreactor(AIPBR)was developed,featuring an inner cylinder and a flow guide tube to create distinct oxygen gradients,facilitating the study of microbial adaptation under varying salt conditions.The AIPBR was operated with synthetic wastewater containing ammonium concentrations of 1800±100 mg/L and salinity gradients ranging from 1 to 10 g/L,followed by a fixed salinity period at 6 g/L,with ammonium concentrations approximately 850 mg/L.High-throughput metagenomic analysis revealed shifts in functional genes and metabolic pathways in response to salinity stress.Anammox bacteria adapted by enriching genes involved in the synthesis of osmoprotective compounds and activating energy-producing pathways like the tricarboxylic acid cycle(TCA).These adaptations,along with modifications in membrane composition,were essential for sustaining system stability under elevated salinity.Under prolonged high salinity stress,anaerobic ammonium oxidizing(AnAOB)exhibited improved salt tolerance,maintaining a total nitrogen removal efficiency above 85%and stabilizing after an adaptation phase.The metagenomic data revealed a marked enrichment of genes associated with ion transport,stress response mechanisms,and DNA repair pathways.Changes in microbial community composition favored salt-tolerant species,supporting system stability.These findings highlight the applicability of the developed bioreactor for scaling up the PNA process to handle high-salinity wastewater,providing a promising avenue for sustainable nitrogen removal in challenging environments. 展开更多
关键词 Anammox bacteria Salinity stress Metagenomics Nitrogen removal Microbial adaptation
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Mesolimbic Dopaminergic Encoding of Decision Value:Linking Phenotype-Specific Signals to Strategic Adaptation 认领 引用 被引量：1
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作者 Zhengyi Xu Dadao An +2 位作者 Jingjia Liang Lingyan Zheng Zhong Chen 《Neuroscience Bulletin》 SCIE CAS CSCD 2026年第4期937-940,共4页
Numerous neuropsychiatric disorders are characterized by significant impairments in decision-making function.These include impulsive decision-making in attention-deficit hyperactivity disorder(ADHD)[1],excessive risk-... Numerous neuropsychiatric disorders are characterized by significant impairments in decision-making function.These include impulsive decision-making in attention-deficit hyperactivity disorder(ADHD)[1],excessive risk-taking during manic episodes in bipolar disorder,and the distorted prioritization observed in substance use disorders.Decisionmaking involves reflecting on the outcomes of past actions and weighing the potential consequences of future actions.In this complex balancing process,mesolimbic dopamine influences reward value assessment,the strength of motivation,and the initiation of action[2]. 展开更多
关键词 phenotype specific signals bipolar disorderand strategic adaptation decision making reflecting outcomes past actions mesolimbic dopaminergic encoding distorted prioritization balancing processmesolimbic dopamine
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Climate Adaptation Pathways for Cities in Albania 认领 引用
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作者 Meivis Struga Oltion Marko +1 位作者 Megi Caushaj Mikael Lako 《Journal of Environmental Science and Engineering(B)》 2026年第2期55-58,共4页
The paper aims to provide insight on the level of risk and hazards that municipality of Shkoder is exposed of.Shkodra is one of the municipalities in Albania most exposed to natural hazards with floods,landslides,and ... The paper aims to provide insight on the level of risk and hazards that municipality of Shkoder is exposed of.Shkodra is one of the municipalities in Albania most exposed to natural hazards with floods,landslides,and wildfires emerging as critical risks.The municipality’s geographic position,surrounded by rivers,lakes and mountainous terrain,makes it particularly vulnerable to climate-related shocks.Seasonal floods have historically disrupted communities and infrastructure,while slope instability in mountainous areas creates frequent landslide risks.In addition,hotter and drier summers have contributed to an increasing incidence of wildfires,threatening forests,agricultural land and settlements.Vulnerable groups in urban Shkodër will face overheating risks,while upland villages may experience water shortages and loss of pasture productivity.Shkodër’s ecosystems face significant threats,especially wetlands around Lake Shkodër and Velipojë,which are vital habitats for migratory birds and fish.Rising temperatures,fluctuating water levels,and invasive species will continue to undermine biodiversity,with knock-on effects for tourism and fisheries that depend on healthy natural systems.Landslides and soil erosion in mountain areas such as Theth,Shalëand Dukagjin are expected to increase due to heavy precipitation events. 展开更多
关键词 Climate change adaptation risk and hazards climate adaptations pathways and options
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Body-environment Temperature Relationships in Desert-dwelling Amphibians and Reptiles:Implications for Ecological Adaptation Strategy 认领 引用
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作者 Meiqing LIU Hanqi LI +9 位作者 Ruoyao NI Bo CAI Run YU Cheng SHEN Runliang ZHAI Liming CHANG Cheng LI Bin WANG Jianping JIANG Wei ZHU 《Asian Herpetological Research》 SCIE CAS CSCD 2026年第2期134-146,共13页
Body surface temperature(Tb)is a key determinant of physiological performance,behavior,and fitness in ectotherms,and its dynamic variation provides critical insights into thermal adaptation.However,field-based data on... Body surface temperature(Tb)is a key determinant of physiological performance,behavior,and fitness in ectotherms,and its dynamic variation provides critical insights into thermal adaptation.However,field-based data on Tb and its relationship with microhabitat temperature(Te)remain scarce for amphibians and reptiles inhabiting extreme arid desert ecosystems in China.While considerable related research has been conducted in desert regions of Africa,the United States,and Australia,the unique climatic and ecological characteristics of Chinese deserts highlight the urgent need for regional thermal ecology data to fill this knowledge gap.Using infrared thermal imaging,a non-invasive approach to temperature measurement,we quantified Tb(Tb-h,head surface temperature;Tb-d,dorsal surface temperature)and Te in two amphibian and four reptile species from the Tarim River Basin to investigate their thermoregulatory strategies under extreme desert conditions.Our results revealed substantial interspecific variation in Tb.Reptiles generally exhibited higher Tb than amphibians,with the highest species-level mean exceeding 40°C.Within species,significant differences between Tb-h and Tb-d were detected in both amphibians and reptiles,indicating heterogeneous thermal demands among body regions;however,the patterns of these differences were species specific.With respect to TbTe relationships,most species showed strong positive correlations between Tb and Te,with the notable exception of Bufotes pewzowi.This species exhibited basking behavior and appeared capable of exploiting thermal gradients to maintain distinct thermal patterns during daytime compared with nighttime.Collectively,these findings highlight the diversity of Tb patterns among desert ectotherms and underscore the importance of integrating behavioral,physiological,and environmental data to better understand their ecological adaptations and vulnerability to climate change.Our study further demonstrates the utility of infrared thermal imaging as a real-time,non-invasive tool for assessing ectotherm thermal ecology in the field. 展开更多
关键词 adaptation basking ectotherm thermal imaging thermoregulation
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