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Development and Factorial Structure of the Green Crescent Life Skills Scale for Turkish Adolescents 认领 引用
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作者 Ayşe Esraİşmen Gazioğlu Halime Yıldırım Hoş Şener Büyüköztürk 《International Journal of Mental Health Promotion》 2025年第5期683-700,共18页
Background The effectiveness of life skills-based prevention programs to prevent substance addiction has been underexplored in Türkiye,likely in part due to the lack of validated measurement tools developed speci... Background The effectiveness of life skills-based prevention programs to prevent substance addiction has been underexplored in Türkiye,likely in part due to the lack of validated measurement tools developed specifically for that purpose.Therefore,the aim of this study is to develop a tool to measure life skills for middle school students.The present study aims to test the factorial structure,reliability,convergent and discriminant validity,and measurement invariance across gender and age groups of the Green Crescent Life Skills(GCLS)Scale.Methods The study was conducted in Istanbul with two different sample groups.The first sample consisted of 566 and the second sample consisted of 885 middle school students.In the study,exploratory factor analysis(EFA)was applied to the first sample,and confirmatory factor analysis(CFA)was applied to the second sample to test the factorial structure of the scale.Convergent and discriminant validity were examined to provide evidence for construct-based validity.The reliability of the scale was assessed with Cronbach’sα,composite reliability,McDonald’sω,and test-retest.Results The EFA results showed that the scale consisted of four factors(self-awareness,coping with negative emotions,thinking skills,and peer relations).CFA results also confirmed this structure.The results revealed a significant positive correlation(r=0.52,p<0.01)between life skills and avoidance self-efficacy scores,as well as a significant negative correlation(r=−0.53,p<0.01)between life skills and attitude toward drug use scores.Additionally,it was found that measurement invariances based on gender and age groups were provided.It was determined that all sub-dimensions had sufficient reliability levels.Conclusion The findings of this validation study show that the GCLS Scale,which assesses four skills in a self-reported format,is a valid and reliable scale with considerable potential utility in monitoring life skills in Turkish adolescent populations. 展开更多
关键词 Green crescent life skills scale life skills drug prevention scale development
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Quantitative analysis on the dynamic characteristics of megadunes around the Crescent Moon Spring, China 认领 引用 被引量：7
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作者 YingJun PANG JianJun QU +2 位作者 KeCun ZHANG ZhiShan AN QingHe NIU 《Journal of Arid Land》 SCIE CSCD 2014年第3期255-263,共9页
The Crescent Moon Spring is a precious natural heritage. However, the dynamic characteristics of megadunes around the Crescent Moon Spring are not well known. This paper quantitatively studied the character- istics an... The Crescent Moon Spring is a precious natural heritage. However, the dynamic characteristics of megadunes around the Crescent Moon Spring are not well known. This paper quantitatively studied the character- istics and changes of megadunes around the Crescent Moon Spring by interpreting aerial photographs taken in 1985 and 2004 and analysing the dune crestlines and the wind data collected from 2011 to 2012. Results revealed that pyramid dunes were formed by a complex wind regime. The Crescent Moon Spring was not buried by shifting sands because of the stable wind regime and relative stability of pyramid dunes. The crestlines of the dunes around the spring moved northward between 1985 and 2004. The south-facing slip faces were also exposed to wind ero- sion, whereas the other faces were under deposition, thus indicating that the southerly wind was relatively en- hanced. Limiting the scale of tall windbreaks and architectures in the Dunhuang oasis at the north of the spring was necessary to maintain the dynamic equilibrium of the wind regime and sand transport. 展开更多
关键词 Dunhuang city Crescent Moon Spring pyramid dunes dynamic characteristics erosion and deposition
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Bacterial diversity in the sediment of Crescent Moon Spring,Kumtag Desert,Northwest China 认领 引用 被引量：2
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作者 ZHANG Wei ZHANG Gaosen +5 位作者 WU Xiukun LIU Guangxiu DONG Zhibao QU Jianjun WANG Yun CHEN Tuo 《Journal of Arid Land》 SCIE CSCD 2017年第2期278-286,共9页
Desert lake, a unique oasis in desert ecosystems, harbours different bacterial communities. Thus, it is considered as a hub of bacterial diversity. In this study, bacterial diversity in the sediment of Crescent Moon S... Desert lake, a unique oasis in desert ecosystems, harbours different bacterial communities. Thus, it is considered as a hub of bacterial diversity. In this study, bacterial diversity in the sediment of Crescent Moon Spring, Kumtag Desert, Northwest China was analyzed using high-throughput amplicon pyrosequencing analysis. The sequences of the most abundant OUTs （Operational Taxonomic Units） in the sediment of Crescent Moon Spring were compared with the sequences of those most abundant OUTs of various origins from NCBI GenBank database to detect the origins of bacteria in the sediment of Crescent Moon Spring. Also, bacterial compositions between sediment of Crescent Moon Spring and other desert and lake ecosystems （including desert lakes） worldwide were compared using cluster analysis to determine the possible factors affecting bacterial compositions. In total, 11,855 sequences were obtained and 30 phyla were identified. At the phylum level, the dominant phylum was Proteobacteria with α-Proteobacteria being the first dominant class and the second dominant phylum was Planctomycetes. Our finding that α-Proteobacteria being the first dominant class of Proteobacteria and Planctomycetes being the second dominant phyla are somewhat contradictory with reports from other desert lake sediments. This difference could be resulted from water hydration and conductivity, as well as oligotrophic conditions of Crescent Moon Spring. At the genus level, Rhodobacter, Caldilinea, Planctomyces, and Porphyrobacterwere the dominant genera in the sediment of Crescent Moon Spring. Comparisons on sequences of the most abundant OUTs （including OTU3615, OTU6535, and OTU6646） between sediment of Crescent Moon Spring and various origins from NCBI GenBank database indicate that the origins of bacteria in the sediment of Crescent Moon Spring are likely from the underground water. Furthermore, cluster analysis on comparisons of bacteria compositions between sediment of Crescent Moon Spring and other desert and lake ecosystems （including desert lakes） worldwide shows that at regional scales, bacterial compositions may be mainly affected by geographical patterns, precipitation amounts, and pH values. Collectively, our results provide new knowledge on the bacterial diversity in desert lake ecosystems. 展开更多
关键词 bacterial diversity pyrosequencing analysis desert lake desert and lake ecosystems Crescent Moon Spring
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Morphological variation of star dune and implications for dune management: a case study at the Crescent Moon Spring scenic spot of Dunhuang, China 认领 引用 被引量：2
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作者 ZHANG Weimin TAN Lihai +3 位作者 AN Zhishan ZHANG Kecun GAO Yang NIU Qinghe 《Journal of Arid Land》 SCIE CSCD 2019年第3期357-370,共14页
Aerial photographs and 3-D laser scans of a 90-m high star dune at the Crescent Moon Spring scenic spot in Dunhuang,China,are used to investigate the changes in dune morphology on timescales from months to decades.The... Aerial photographs and 3-D laser scans of a 90-m high star dune at the Crescent Moon Spring scenic spot in Dunhuang,China,are used to investigate the changes in dune morphology on timescales from months to decades.The result revealed that relative-equilibrium airflow strength in three wind directions of northeast,west and south was an important condition for the stability of star dunes with limited migration.Transverse and longitudinal airflows exerted a crucial impact on variation processes of star dune morphology.Controlled by transverse airflows,the easterly winds,the east side was dominated by wind erosion;and strong deposition occurred on the south-south-east arm with a maximum deposition rate of 0.44 m/a in the 46-a monitoring period,causing the east side becoming steep and high.Controlled by longitudinal airflows,the westerly winds,the west-north-west side was mainly eroded and the north arm migrated from west to east with a rate of 0.30 m/a,causing the dune slope becoming gentle and elongate.The local air circulation(southerly winds)exerted a significant impact on the development process of the star dune.Due to the influence of human activities,the south side present surface processes from a concave profile to a convex profile in 46 a,which is a potential threat to the Crescent Moon Spring.The results indicate that rehabilitating the airflow field at most is a crucial strategy to the protection of Crescent Moon Spring from burial.Opening up the passage of easterly,westerly and southerly winds through intermediately cutting the protection forest,demolishing the enclosed wall and changing the pavilion into a porous pattern have been suggested to protect the Crescent Moon Spring from burial. 展开更多
关键词 star dune morphology variation erosion and deposition time scale Crescent Moon Spring
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Progress on research and mitigation of wind-blown sand risk in Dunhuang Singing Sand Mountain and Crescent Spring Scenic area,China 认领 引用 被引量：1
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作者 BenLi Liu KeCun Zhang +6 位作者 JianJun Qu HaiJiang Li QingHe Niu ZhiShan An YingJun Pang LiHai Tan GenSheng Yang 《Research in Cold and Arid Regions》 CSCD 2023年第3期113-121,共9页
The Singing Sand Mountain and Crescent Spring Scenic Spot in Dunhuang,Northwest China is a world-renowned desert attraction that is also an integral component of the Dunhuang UNESCO Global Geopark.This scenic area und... The Singing Sand Mountain and Crescent Spring Scenic Spot in Dunhuang,Northwest China is a world-renowned desert attraction that is also an integral component of the Dunhuang UNESCO Global Geopark.This scenic area underwent a 30-year transformation,i.e.,from a severe sand risk with spring water threatened by sand burial due to dune deformation,to restoration of the original sand flow field and mitigation of the sand burial problem.The current paper summarizes the research on the intensive monitoring of the dynamic change of star dunes near the spring,observation of wind and sand flow movement,and then restoring the harmonic vibration of the sand particles(singing sand)that were previously silenced.The existing and prospective impacts of anthropogenic and natural forces on the deformation of the sand dunes are investigated by integrated methods,guiding the implementation of mitigating measures with significant ameliorative effects.Contrast to common sand control practices that aim to reduce wind speed and stop blown sands,our research highlights the importance of maintaining the natural wind flow field in stabilizing surrounding dunes.These mitigation measures consist of removing excessive vegetation and newly constructed buildings to recover the original wind flow field and sand transport activity.Such research and mitigation efforts ensure the scientific protection and restoration of the special desert landform,and contribute to the mutual enhancement of the conservation and exploitation of this desert scenic spot and similar sites. 展开更多
关键词 Singing Sand Mountain Crescent Spring Wind-blown sand problem Wind flow field Star dune
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Evolution of crescent-shaped sand dune under the influence of injected sand flux:scaling law and wind tunnel experiment 认领 引用
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作者 ZHANG Yang WANG Yuan +1 位作者 ZHOU Xiaosi YANG Bin 《Journal of Arid Land》 SCIE CSCD 2017年第2期270-277,共8页
This paper studies the evolution of crescent-shaped dune under the influence of injected flux. A scaling law and a wind tunnel experiment are carried out for comparison. The experiment incorporates a novel image proce... This paper studies the evolution of crescent-shaped dune under the influence of injected flux. A scaling law and a wind tunnel experiment are carried out for comparison. The experiment incorporates a novel image processing algorithm to recover the evolutionary process. The theoretical and experimental results agree well in the middle stage of dune evolution, but deviate from each other in the initial and final stages, suggesting that the crescent-shaped dune evolution is intrinsically scale-variant and that the crescent shape breaks down under unsaturated condition. 展开更多
关键词 crescent-shaped sand dune scale-invariant model wind tunnel experiment image processing
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Grain size distribution at four developmental stages of crescent dunes in the hinterland of the Taklimakan Desert,China 认领 引用 被引量：5
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作者 JIA Wenru ZHANG Chunlai +3 位作者 LI Shengyu WANG Haifeng MA Xuexi WANG Ningbo 《Journal of Arid Land》 SCIE CSCD 2016年第5期722-733,共12页
Although scientists have performed many studies on crescent （barchan） dunes in the Taklimakan Desert,few studies reported the changes in grain size at different development stages of crescent dunes.In order to evalu... Although scientists have performed many studies on crescent （barchan） dunes in the Taklimakan Desert,few studies reported the changes in grain size at different development stages of crescent dunes.In order to evaluate the changing trends of surface sediment grain size with dune development,we investigated the grain size characteristics at four developmental stages （oval sand pile,shield dune,incipient crescent dune and mature crescent dune） of crescent dunes by measuring the morphology of sand dune and observing the near-surface wind regime.The dunes have developed in a wide inter-dune corridor between high compound longitudinal ridges in China＇s Taklimakan Desert.The surface sediments at four developmental stages of the crescent dunes were primarily composed of fine sands,followed by very fine and medium sands.Mean grain sizes ranged from 2.8 to 3.1 φ,with a unimodal distribution.The sands were moderately well-sorted,their distribution varied from platykurtic to very platykurtic,and symmetrical or skewed towards the fine particles.From oval sand piles through shield and incipient crescent dunes to mature crescent dunes,incipient grain size gradually increased,particles became finer,sorting became better,kurtosis and skewness increased.Grain sizes on the surface layer became coarser upwards from the toe of the windward slope and then became finer towards the bottom of the leeward slope.We found that the coarsest particles at different positions at the four developmental stages were different.The coarsest particles were distributed at the top of the oval sand piles and shield dunes,versus at the middle of the windward slope of the incipient and mature crescent dunes.Correlations between the mean grain size and other grain size parameters showed that as mean grain size became finer,sorting became better and kurtosis became wider,but skewness changed only slightly.In addition,grain size variation in the surface sediments correlated with the movement speed of the dunes in the study area.In the open ground among tall-complex longitudinal ridges in the hinterland of the Taklimakan Desert where aeolian environment is characterized by comparatively strong wind and unsaturated sand flow,faster dune movement corresponded to coarser grain size. 展开更多
关键词 crescent dune developmental stage grain size Taklimakan Desert
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Experimental study on modulational instability and evolution of crescent waves 认领 引用 被引量：1
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作者 Ya-long ZHOU Zhi-li ZOU Kai YAN 《Water Science and Engineering》 EI CAS 2012年第4期419-427,共9页
A series of experiments on the instability of steeP water wave trains in water with finite water depths and infinite water depths in a wide wave basin were performed. It was found that under the coupled development of... A series of experiments on the instability of steeP water wave trains in water with finite water depths and infinite water depths in a wide wave basin were performed. It was found that under the coupled development of modulational instability and class-Ⅱ instability, the initial two-dimensional steep wave trains evolved into three＇dimensional crescent waves, followed by the occurrence of disordered water surfaces, and that the wave energy transferred to sidebands in the amplitude spectrum of the water surface elevation. The results also show that water depth has a significant effect on the growth of modulational instability and the evolutiin of crescent waves. The larger the water depth, the more quickly the modulational instability suppresses class-II instability. 展开更多
关键词 modulational instability class-H instability crescent wave amplitude spectrum wave energy transfer
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Antineutrophil cytoplasmic antibodies crescentic allograft glomerulonephritis after sofosbuvir therapy 认领 引用 被引量：2
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作者 Shilpa Gadde Belinda Lee +1 位作者 Laura Kidd Rubin Zhang 《World Journal of Nephrology》 2016年第6期547-550,共4页
Antineutrophil cytoplasmic antibodies(ANCA) are well known to be associated with several types of vasculitis, including pauci-immune crescentic glomerulonephritis, a form of rapid progressive glomerular nephritis(RPGN... Antineutrophil cytoplasmic antibodies(ANCA) are well known to be associated with several types of vasculitis, including pauci-immune crescentic glomerulonephritis, a form of rapid progressive glomerular nephritis(RPGN). ANCA vasculitis has also been reported after administration of propylthiouracil, hydralazine, cocaine(adulterated with levimasole), allopurinol, penicillamine and few other drugs. All previously reported cases of drug-associated ANCA glomerulonephritis were in native kidneys. Sofosbuvir is a new and effective drug for hepatitis C virus infection. Here, we report a case of ANCA vasculitis and RPGN following sofosbuvir administration in a kidney transplant recipient. It also represents the first case of drug-associated ANCA vasculitis in a transplanted kidney. Further drug monitoring is necessary to elucidate the degree of association and possible causal effect of sofosbuvir and perinuclear ANCA vasculitis. 展开更多
关键词 Crescentic glomerulonephritis Vasculitis Antineutrophil cytoplasmic antibody Sofosbuvir Kidney transplant
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Accuracy of crescent sign on ocular ultrasound in diagnosing papilledema 认领 引用 被引量：1
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作者 Ananth Bhosale Virna M Shah Parag K Shah 《World Journal of Methodology》 2017年第3期108-111,共4页
AIM To study the usefulness of orbital ultrasonography in the diagnosis of papilledema.METHODS Fifty patients who were referred to the neurophthalmology clinic and clinically suspected to have papilledema were selecte... AIM To study the usefulness of orbital ultrasonography in the diagnosis of papilledema.METHODS Fifty patients who were referred to the neurophthalmology clinic and clinically suspected to have papilledema were selected. Thorough, clinical examination with slitlamp biomicroscopy and visual acuity assessment was done. These patients underwent ultrasonography to demonstrate the crescent sign. The patients were further evaluated with the neurologist and magnetic resonance imaging(MRI) thus confirming the diagnosis of papilledema. The results of our ultrasonographic evaluation were correlated with final diagnosis after thorough clinical evaluation, imaging and the neurologist's opinion.RESULTS Out of 50 patients diagnosed having papilledema on MRI, 46(92%) showed crescent sign on B scan ultrasonography. Headache was most common presenting complaint in 47(94%) and idiopathic intracranial hypertension was most common underlying cause of papilledema in 30(60%) cases.CONCLUSION"Crescent sign" seen on ultrasonography is a sensitive tool for diagnosis of papilledema. It is cost effective, less cumbersome and effective tool to differentiatebetween papilledema and pseudo papilledema before subjecting the patients to costly investigations like MRI. A positive crescent sign should always be followed by MRI to find out the cause of papilledema. 展开更多
关键词 Papilledema Orbital ultrasound Doughnut sign Crescent sign B scan
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A Restrained Iran:Consolidating the Shiite Crescent 认领 引用
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作者 Qin Tian 《Contemporary International Relations》 2017年第5期20-28,共9页
The Arab Spring is supposed to be the Arab world’s great changes and turmoil,but Iran has repeatedly become the focus in the following changes.Whether it is in the Syrian civil war,or strikes against ISIS,or the Qata... The Arab Spring is supposed to be the Arab world’s great changes and turmoil,but Iran has repeatedly become the focus in the following changes.Whether it is in the Syrian civil war,or strikes against ISIS,or the Qatar crisis,Iran repeatedly appeared.There are different attitudes towards Iran’s behavior.The Trump administration holds the opinion that Iran is 展开更多
关键词 A Restrained Iran:Consolidating the Shiite Crescent
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应用Crescent双腔导管的改良静脉-动脉体外膜肺氧合联合介入手术治疗高危型肺栓塞患者1例 认领 引用
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作者 张科 莫松 +2 位作者 韦金豆 陈兆菁 苏奕明 《中华危重病急救医学》 CAS CSCD 北大核心 2026年第5期481-485,共5页
高危型肺栓塞起病急骤,进展迅猛,病死率高,建立高效的多学科协作救治体系至关重要。本文报道1例因跌倒致多发伤、下肢深静脉血栓形成后突发高危型肺栓塞患者的救治过程。患者男性,61岁,因"跌倒致全身多发伤5 d,气促8 h"于2024... 高危型肺栓塞起病急骤,进展迅猛,病死率高,建立高效的多学科协作救治体系至关重要。本文报道1例因跌倒致多发伤、下肢深静脉血栓形成后突发高危型肺栓塞患者的救治过程。患者男性,61岁,因"跌倒致全身多发伤5 d,气促8 h"于2024年8月入住广西医科大学第四附属医院。患者5 d前因跌倒致全身多发伤在河池市第一人民医院住院治疗,其间因下肢深静脉血栓形成置入下腔静脉滤器,滤器置入术后次日出现呼吸困难,经呼吸机辅助通气、血管活性药物支持后仍存在顽固性低氧血症〔脉搏血氧饱和度(SpO2)80%~85%〕和血流动力学不稳定(休克指数>1),急查胸部增强CT提示右肺动脉主干栓塞。经外院联系,广西医科大学第四附属医院肺栓塞救治团队(PERT)立即启动跨区域驰援,到外院后应用Crescent双腔导管紧急建立改良静脉-动脉体外膜肺氧合(V-A ECMO)以稳定循环,继而在ECMO支持下安全转运回广西医科大学第四附属医院,并急诊行介入手术吸除肺动脉血栓,术后血流动力学和血氧改善,术后第1天成功撤除ECMO(ECMO总运行时间约28 h),撤机后面罩吸氧下动脉血氧饱和度(SaO2)达97.8%,休克指数降至0.83。患者于术后第5天可下床活动,无胸闷气促,术后3、6、12个月电话随访恢复良好。本例患者的成功救治,验证了"跨区域PERT协作-改良V-A ECMO支持-介入手术"一体化模式在救治存在转运风险的高危型肺栓塞患者中的有效性与可行性。该模式能够快速、安全地建立高级生命支持,为后续介入手术创造了条件,是处理此类复杂高危型肺栓塞病例的一种有效策略,但其整体流程的优化和普适性仍需更大样本的临床研究进一步实践和验证。 展开更多
关键词 Crescent双腔导管 肺栓塞 改良静脉-动脉体外膜肺氧合 AngioJet 肺栓塞救治团队
Crescent jugular dual-lumen catheter for adult veno-venous extracorporeal membrane oxygenation in China:Multicenter initial experience 认领 引用
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作者 Han Zhang Gang Liu +12 位作者 Xiaojun Liu Yang Yan Xiaozu Liao Junmeng Zheng Songqiao Liu Zhen Guo Jian Rong Fangqiang Song Chunyao Wang Zan Chen Chengbin Zhou Man Huang Bingyang Ji 《Chinese Medical Journal Pulmonary and Critical Care Medicine》 2025年第2期141-143,共3页
To the Editor Veno-venous extracorporeal membrane oxygenation(V-V ECMO)is a life support technique used for patients with life-threatening respiratory failure.It effectively addresses arterial hypoxemia without overst... To the Editor Veno-venous extracorporeal membrane oxygenation(V-V ECMO)is a life support technique used for patients with life-threatening respiratory failure.It effectively addresses arterial hypoxemia without overstretching the injured lungs.Traditional adult V-V ECMO typically requires two-site,single-lumen cannulas inserted into the femoral and jugular/subclavian veins or both femoral veins.However,this approach can increase the risk of local complications(such as infection and bleeding)and limit patient mobility. 展开更多
关键词 life support technique local complications arterial hypoxemia veno venous extracorporeal membrane oxygenation adult patient mobility crescent jugular dual lumen catheter
基于Kriging模型与遗传算法的月牙肋钢岔管结构优化设计 认领 引用 被引量：2
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作者 蒋莉 马增辉 +1 位作者 许新勇 刘宪亮 《华北水利水电大学学报（自然科学版）》 北大核心 2026年第3期123-132,共10页
【目的】月牙肋钢岔管是目前抽水蓄能电站最常用的岔管形式,本研究旨在实现兼顾其结构安全性和经济性的高效优化设计。【方法】针对岔管结构设计时的结构非线性和设计参数响应值之间复杂的隐式关系,采用三维参数化建模和拉丁超立方采样... 【目的】月牙肋钢岔管是目前抽水蓄能电站最常用的岔管形式,本研究旨在实现兼顾其结构安全性和经济性的高效优化设计。【方法】针对岔管结构设计时的结构非线性和设计参数响应值之间复杂的隐式关系,采用三维参数化建模和拉丁超立方采样进行试验设计,利用Kriging模型建立包括管壁厚度、肋板厚度和肋板中央截面宽度在内的岔管关键设计参数和关键点Mises应力的非线性映射关系,通过遗传算法实现岔管体型参数的最佳寻优方案。【结果】优化后的岔管体积与原设计相比由20.901m3变为15.780m3,减小24.5%;岔管各部位应力分布均匀,均低于规范允许的抗力限值,钢材强度得以充分发挥,且相邻椎管段壁厚差值满足焊接要求。【结论】采用该方法能够在确保结构安全的前提下有效降低钢材用量,提高月牙肋钢岔管优化设计效率和精度,并可为类似岔管的优化设计提供参考。 展开更多
关键词 月牙肋钢岔管 Kriging模型 结构优化 遗传算法
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Clinical spectrum of diffuse crescentic glomerulonephritis in Chinese patients 认领 引用 被引量：10
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作者 唐政 吴燕 +6 位作者 王庆文 曾彩虹 姚小丹 胡伟新 陈惠萍 刘志红 黎磊石 《Chinese Medical Journal》 SCIE CAS 2003年第11期1737-1740,共4页
Objective To investigate retrospectively the incidence, distribution of primary disease and clinicopathologic characteristics of diffuse crescentic glomerulonephritis (DCGN) in Chinese patients.Methods One hundred and... Objective To investigate retrospectively the incidence, distribution of primary disease and clinicopathologic characteristics of diffuse crescentic glomerulonephritis (DCGN) in Chinese patients.Methods One hundred and seventy-two consecutive patients diagnosed as having DCGN out of 9828 cases of non-transplanting renal biopsies over sixteen years, were studied. DCGN is categorized into three types according to immunopathologic characteristics. The incidence of this disease, its primary diseases, clinical characteristics and serum antineutrophil cytoplasmic antibodies (ANCAs) were analyzed.Results The distribution of patients among the three classifications was 8. 7% type Ⅰ , 68. 6% type Ⅱ and 22. 7% type Ⅲ. Clinically, the majority of patients (69.8%) presented rapidly progressive glomerulonephritis (RPGN), but 30. 2% manifested a chronic nephritic syndrome or chronic renal failure. In terms of related conditions, 93% were anemic, 61. 6% had hypertension, 50. 6% oliguria, 45.3% nephrotic syndrome, 43% uremic syndrome and 39.5% displayed gross hematuria. Those patients who were positive in serum for ANCAs had predominantly type Ⅲ DCGN. Two cases with anti-GBM-antibody crescentic glomerulonephritis and three with lupus nephritis were also positive for ANCAs in serum.Conclusion DCGN is not rare in Chinese patients. A majority of patients in our study presented with RPGN, but 30. 2% manifested a chronic renal failure. Lupus patients with DCGN that were positive for ANCAs had more severe vasculitic lesions. 展开更多
关键词 diffuse · crescentic glomerulonephritis ·antineutropM cytoplasmic antibodies
Infective Endocarditis-induced Crescentic Glomerulonephritis Dramatically Improved after Removal of Vegetations and Valve Replacement 认领 引用 被引量：4
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作者 Min Yang Guo-Qin Wang +1 位作者 Yi-Pu Chen Hong Cheng 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第3期404-406,共3页
Infective endocarditis(IE)is associated with poor prognosis and higher mortality.IE-induced glomerulonephritis,especially crescentic glomerulonephritis(IE-CGN)with renal dysfunction,is an independent risk factor for m... Infective endocarditis(IE)is associated with poor prognosis and higher mortality.IE-induced glomerulonephritis,especially crescentic glomerulonephritis(IE-CGN)with renal dysfunction,is an independent risk factor for mortality For the treatment of IE-CGN,many therapeutic strategies including antibiotics alone,antibiotics combined with corticosteroid,immunosuppressive agents,plasmapheresis,or cardiac surgery have been applied and obtained various results.C21 Here,we reported a case of CGN with progressive renal failure secondary to IE in which the renal function was dramatically improved by the treatment of surgical valve replacement and antibiotics. 展开更多
关键词 Infective Endocarditis Crescentic Glomerulonephritis Heart Valve Replacement Surgery
The clinical and pathological characteristics of Chinese patients with pauci-immune crescent glomerulonephritis 认领 引用 被引量：10
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作者 唐政 姚小丹 +4 位作者 胡伟新 曾彩虹 陈惠萍 刘志红 黎磊石 《Chinese Medical Journal》 SCIE CAS 2001年第4期38-42,105,共5页
目的　对寡免疫复合物型新月体肾炎进行临床病理分析。方法　采用病理检查包括 :光镜检查、免疫病理分析、血清学检查、肾功能检查以及统计学分析。结果　 6 4 0 0例非移植肾活检中发现 2 4例寡免疫复合物型新月体肾炎 (PICGN)患者 ,占... 目的　对寡免疫复合物型新月体肾炎进行临床病理分析。方法　采用病理检查包括 :光镜检查、免疫病理分析、血清学检查、肾功能检查以及统计学分析。结果　 6 4 0 0例非移植肾活检中发现 2 4例寡免疫复合物型新月体肾炎 (PICGN)患者 ,占肾活检总数的 0 37% ,占新月体肾炎总数的 2 3 9% ,其中女性 16例 ,男性 8例 ,平均年龄 33岁。血管炎中微型多动脉炎 (33 3% )和结节性多动脉炎 (8 3% )为常见继发病因。抗中性粒细胞胞浆抗体 (ANCA)阳性率为 52 2 %。临床上多表现为急进性肾功能减退 (75 0 % ) ,发作性肉眼血尿发生率高 (58 3% ) ,高血压发生率为 4 5 8% ,肾病综合症发生率为 4 1 7% ,2 5%患者出现少尿无尿症状。除贫血外 ,肾外表现较少。病理上血管襻坏死 (6 2 5% )、单核及中性粒细胞浸润(6 6 7% )及小血管炎等为常见的急性病变 ;然而 ,小球硬化 (4 5 8% )、小管萎缩 (83 3% )、间质纤维化 (75 0 % )等慢性化病变也较严重。 2 2例患者行免疫抑制治疗 ,16例随访 8— 92个月 ,有 4例肾功能在正常范围 (<12 4 μmol/L) ,8例行非透析保守治疗 ,仅 4例进入终末期肾功能衰竭需进行维持性血透析治疗。结论　免疫抑制冲击治疗是治疗PICGN的有效方法。 展开更多
关键词 pauci-immune crescent glomerulonephritis·clinico-pathology·anti-neutrophil cytoplasmic antibody
Significance of anti neutrophil cytoplasmic antibodies in patients with pauci immune crescentic glomerulonephritis 认领 引用 被引量：3
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作者 唐政 周虹 +4 位作者 张少陵 姚小丹 胡伟新 刘志红 黎磊石 《Chinese Medical Journal》 SCIE EI CAS 1999年第12期87-90,共4页
Objective To evaluate the significance of serum anti neutrophil cytoplasmic antibodies (ANCAs) and the effects of immune suppressive treatments on its activity in patients with pauci immune crescentic glomerulonephrit... Objective To evaluate the significance of serum anti neutrophil cytoplasmic antibodies (ANCAs) and the effects of immune suppressive treatments on its activity in patients with pauci immune crescentic glomerulonephritis (PICGN) Methods Serum ANCAs and myeloperoxidase (MPO) ANCA were detected by indirect immunofluorescence and enzyme linked immuno^sorbent assay (ELISA) methods respectively, and the renal tissues infiltrating cells including CD4 +, CD8 +, CD68 + and PCNA + cells were determined by four layer peroxidase antiperoxidase (PAP) method The clinical manifestations, pathologic features and immune pathologic changes in patients with positive ANCAs were compared with that in patients with negative ANCAs The effects of immune suppressive therapy on clinic and pathologic changes as well as ANCAs activity were also investigated in ANCAs positive and ANCAs negative patients Results Both of clinic active manifestations such as the degree of hematuria, rapidly progressive renal failure and pathologic active features including segmental capillary necrosis and vasculitis were much common in patients with positive ANCAs as compared with that in patients with negative ANCAs The number of infiltrating cells in renal tissue, especially CD4 + cells, was markedly higher in ANCAs positive patients than that in ANCAs negative patients The effects of immune suppressive therapy were also much better in patients with positive ANCAs than that in patients with negative ANCAs Conclusion Serum ANCAs is not only a marker for diagnosis of systemic vasculitis, but also a sensitive predictor for evaluation of diseases' activity and treatment in patients with PICGN The good effect of immune suppressive treatments on patients with PICGN is partially associated with the degree of ANCAs activity 展开更多
关键词 anti neutrophil cytoplasmic antibodies pauci immune crescentic glomerulonephritis
The distribution and significance of renal infiltrating cells in patients with diffuse crescentic glomerulonephritis 认领 引用 被引量：4
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作者 唐政 吴燕 +5 位作者 胡伟新 姚小丹 周红 陈惠萍 刘志红 黎磊石 《Chinese Medical Journal》 SCIE CAS 2001年第12期35-37,103-104,共3页
Objective To study the significance and distribution of renal infiltrating cells, including monocytes (CD68+ cells), proliferative cell nuclear antigen positive cells (PCNA+ cells), CD4+ and CD8+ cells in diffuse cres... Objective To study the significance and distribution of renal infiltrating cells, including monocytes (CD68+ cells), proliferative cell nuclear antigen positive cells (PCNA+ cells), CD4+ and CD8+ cells in diffuse crescent glomerulonephritis (DCGN). Methods Fifty-six patients with DCGN were studied, including 10 cases of anti-glomerular basement membrane (GBM)-type Ⅰ DCGN, 26 immune complex-type Ⅱ DCGN, and 20 cases of pauci-immune-type Ⅲ DCGN. Glomerular and interstitial infiltrates of CD68+ and PCNA+ cells, and interstitial infiltrates of CD4+ and CD8+ cells were detected by using four-layer PAP methods. Results There was a significant increase of renal infiltrating CD68+, PCNA+, CD4+ and CD8+ cells in patients with DCGN compared with that in normal controls. In patients with type Ⅰ DCGN, there was a higher number of renal infiltrating CD68+ and PCNA+ cells than that in patients with type Ⅱ and Ⅲ DCGN. A glomerular infiltrates of CD68+ and PCNA+ cells correlated with the interstitial infiltrates of CD4+ cells in type Ⅰ or Ⅲ DCGN patients. In lupus DCGN patients, the numbers of renal infiltrating CD68+ and PCNA+ cells were similar to vasculitis or type Ⅲ DCGN patients.Conclusion These findings demonstrate that the renal infiltrates of CD68+ and PCNA+ cells play an important role in patients with DCGN, that the infiltrates of CD4+ cells correlate with the infiltrates of CD68+ and PCNA+ cells may be an active marker of DCGN, and that cell-mediated immunity may contribute to crescent formation in lupus DCGN patients. 展开更多
关键词 CD68 + cells · PCNA + cells · CD8 + cells · crescentic glomerulonephritis
月牙泉水位恢复补水方案实践与思考 认领 引用
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作者 惠磊 李世珠 +1 位作者 杨文宏 李平平 《节水灌溉》 北大核心 2026年第4期75-78,共4页
月牙泉是敦煌生态“健康状况”的晴雨表,加强月牙泉科学保护和综合治理,是改善敦煌地区生态环境,推进敦煌文化保护与传承的重要举措。基于地下水下降成因与对策分析,结合渗水试验研究,提出以“河道渗水场+地下水限采”为核心的补水方案... 月牙泉是敦煌生态“健康状况”的晴雨表,加强月牙泉科学保护和综合治理,是改善敦煌地区生态环境,推进敦煌文化保护与传承的重要举措。基于地下水下降成因与对策分析,结合渗水试验研究,提出以“河道渗水场+地下水限采”为核心的补水方案。通过构建区域补渗水系统,逐步恢复月牙泉的自然形态与生态功能,为干旱地区名泉保护提供可借鉴的技术范式。 展开更多
关键词 月牙泉 水位恢复 渗水回灌 生态修复
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